Yiyi Yan, MD, PhD

  • 238 Citations
  • 6 Scopus h-Index
20132019
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Research Output 2013 2019

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Article
2019
2 Citations (Scopus)

Case series of dabrafenib-trametinib-induced pyrexia successfully treated with colchicine

Vera, J., Paludo, J., Kottschade, L., Brandt, J., Yan, Y., Block, M. S., Mc Williams, R. R., Dronca, R. S., Loprinzi, C. L., Grothey, A. F. & Markovic, S. N., Jan 1 2019, In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Colchicine
Fever
Mitogen-Activated Protein Kinases
Familial Mediterranean Fever
Therapeutics
1 Citation (Scopus)

Understanding heterogeneous tumor microenvironment in metastatic melanoma

Yan, Y., Leontovich, A. A., Gerdes, M. J., Desai, K., Dong, J., Sood, A., Santamaria-Pang, A., Mansfield, A., Chadwick, C., Zhang, R., Nevala, W. K., Flotte, T. J., Ginty, F. & Markovic, S. N., Jun 1 2019, In : PloS one. 14, 6, e0216485.

Research output: Contribution to journalArticle

Open Access
Tumor Microenvironment
melanoma
Tumors
Melanoma
neoplasms
2018
13 Citations (Scopus)

CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yan, Y., Cao, S., Liu, X., Harrington, S. M., Bindeman, W. E., Adjei, A. A., Jang, J. S., Jen, J., Li, Y., Chanana, P., Mansfield, A. S., Park, S. S., Markovic, S. N., Dronca, R. S. & Dong, H., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
T-Lymphocytes
Drug Therapy
Aptitude
Neoplasms
Therapeutics
5 Citations (Scopus)

Neoadjuvant systemic therapy for regionally advanced melanoma

Jakub, J. W., Racz, J. M., Hieken, T. J., Gonzalez, A. B., Kottschade, L. A., Markovic, S. N., Yan, Y. & Block, M. S., May 1 2018, In : Journal of Surgical Oncology. 117, 6, p. 1164-1169 6 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Melanoma
Disease-Free Survival
3 Citations (Scopus)

Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy

Wu, X., Li, Y., Liu, X., Chen, C., Harrington, S. M., Cao, S., Xie, T., Orzechowski, A., Pham, T., Mansfield, A., Yan, Y., Kwon, E. D., Wang, L. M., Ling, K. & Dong, H. M., Dec 1 2018, In : Heliyon. 4, 12, e01039.

Research output: Contribution to journalArticle

Drug Therapy
Neoplasms
p38 Mitogen-Activated Protein Kinases
Clustered Regularly Interspaced Short Palindromic Repeats
B7 Antigens
2017
6 Citations (Scopus)

Lymphocyte-to-monocyte ratio is associated with survival in pembrolizumab-treated metastatic melanoma patients

Failing, J. J., Yan, Y., Porrata, L. F. & Markovic, S. N., Jan 1 2017, In : Melanoma Research. 27, 6, p. 596-600 5 p.

Research output: Contribution to journalArticle

Monocytes
Melanoma
Disease-Free Survival
Lymphocytes
Survival
2016
13 Citations (Scopus)

CpG-induced antitumor immunity requires IL-12 in expansion of effector cells and down-regulation of PD-1

Yin, P., Liu, X., Mansfield, A., Harrington, S. M., Li, Y., Yan, Y. & Dong, H. M., 2016, In : Oncotarget. 7, 43, p. 70223-70231 9 p.

Research output: Contribution to journalArticle

Interleukin-12
Immunity
Down-Regulation
T-Lymphocytes
Toll-Like Receptor 9
2015
6 Citations (Scopus)

Emergence of a STAT3 mutated NK clone in LGL leukemia

Yan, Y., Olson, T. L., Nyland, S. B., Feith, D. J. & Loughran, T. P., Jan 1 2015, In : Leukemia Research Reports. 4, 1, p. 4-7 4 p.

Research output: Contribution to journalArticle

Large Granular Lymphocytic Leukemia
Clone Cells
Mutation
T-Lymphocytes
Immunologic Monitoring
12 Citations (Scopus)

Molecular profiling in the treatment of colorectal cancer: Focus on regorafenib

Yan, Y. & Grothey, A. F., Oct 15 2015, In : OncoTargets and Therapy. 8, p. 2949-2957 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Therapeutics
Biological Therapy
Genetic Markers
Vascular Endothelial Growth Factor A
2013
146 Citations (Scopus)

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Rajala, H. L. M., Eldfors, S., Kuusanmäki, H., Van Adrichem, A. J., Olson, T., Lagström, S., Andersson, E. I., Jerez, A., Clemente, M. J., Yan, Y., Zhang, D., Awwad, A., Ellonen, P., Kallioniemi, O., Wennerberg, K., Porkka, K., Maciejewski, J. P., Loughran, T. P., Heckman, C. & Mustjoki, S., May 30 2013, In : Blood. 121, 22, p. 4541-4550 10 p.

Research output: Contribution to journalArticle

Large Granular Lymphocytic Leukemia
STAT3 Transcription Factor
Genes
Mutation
Phosphorylation