• 5148 Citations
  • 38 Scopus h-Index
19972019
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Research Output 1997 2019

  • 5148 Citations
  • 38 Scopus h-Index
  • 135 Article
  • 5 Letter
  • 2 Comment/debate
  • 1 Chapter
2019

Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Wang, Y., Wenzl, K., Manske, M. K., Asmann, Y., Sarangi, V., Greipp, P. T., Krull, J. E., Hartert, K., He, R., Feldman, A. L., Maurer, M. J., Slager, S. L., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Link, B. K., Ansell, S. M., Cerhan, J. R. & Novak, A. J., Sep 1 2019, In : Blood cancer journal. 9, 9, 73.

Research output: Contribution to journalArticle

Open Access
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Immunotherapy
Lymphoma
Hodgkin Disease
5 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., Van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R. V., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation

Host genetic variation in tumor necrosis factor and nuclear factor-κB pathways and overall survival in mantle cell lymphoma: A discovery and replication study

Wang, Y., Habermann, T. M., Wang, S. S., Maurer, M. J., Sarangi, V., Link, B. K., Feldman, A. L., Inwards, D. J., Witzig, T. E., Cozen, W., Rothman, N., Asmann, Y., Slager, S. L. & Cerhan, J. R., Jan 1 2019, In : American journal of hematology.

Research output: Contribution to journalLetter

Open Access
Mantle-Cell Lymphoma
Tumor Necrosis Factor-alpha

Managing genomic variant calling workflows with Swift/T

Ahmed, A. E., Heldenbrand, J., Asmann, Y., Fadlelmola, F. M., Katz, D. S., Kendig, K., Kendzior, M. C., Li, T., Ren, Y., Rodriguez, E., Weber, M. R., Wozniak, J. M., Zermeno, J. & Mainzer, L. S., Jan 1 2019, In : PloS one. 14, 7, e0211608.

Research output: Contribution to journalArticle

Open Access
Workflow
genomics
bioinformatics
management systems
Bioinformatics

MYC dysregulation in the progression of multiple myeloma

MMRF CoMMpass Network, Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalLetter

Multiple Myeloma
1 Citation (Scopus)

NucMap: a database of genome-wide nucleosome positioning map across species

Zhao, Y., Wang, J., Liang, F., Liu, Y., Wang, Q., Zhang, H., Jiang, M., Zhang, Z., Zhao, W., Bao, Y., Zhang, Z., Wu, J., Asmann, Y., Li, R. & Xiao, J., Jan 8 2019, In : Nucleic Acids Research. 47, D1, p. D163-D169

Research output: Contribution to journalArticle

Nucleosomes
Genome
Databases
Chromatin
Biological Phenomena
1 Citation (Scopus)

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Ebbert, M. T. W., Jensen, T. D., Jansen-West, K., Sens, J. P., Reddy, J. S., Ridge, P. G., Kauwe, J. S. K., Belzil, V., Pregent, L., Carrasquillo, M. M., Keene, D., Larson, E., Crane, P., Asmann, Y., Taner, N., Younkin, S. G., Ross, O. A., Rademakers, R. V., Petrucelli, L. & Fryer, J. D., May 20 2019, In : Genome biology. 20, 1, 97.

Research output: Contribution to journalArticle

Open Access
gene
Technology
Alzheimer disease
Genes
Alzheimer Disease
2018
3 Citations (Scopus)

A susceptibility locus for classical Hodgkin lymphoma at 8q24 near MYC/PVT1 predicts patient outcome in two independent cohorts

Ghesquières, H., Larrabee, B. R., Casasnovas, O., Maurer, M. J., McKay, J. D., Ansell, S. M., Montgomery, D., Asmann, Y., Farrell, K., Verney, A., Slager, S. L., Allmer, C., Perrot, A., Delarue, R., Habermann, T. M., Dupuis, J., Link, B. K., Canioni, D., Dogan, A., Cozen, W. & 3 others, Jarrett, R. F., Cerhan, J. R. & Salles, G., Jan 1 2018, In : British Journal of Haematology. 180, 2, p. 286-290 5 p.

Research output: Contribution to journalLetter

Leupeptins
Long Noncoding RNA
Chromosomes, Human, Pair 8
myc Genes
Genetic Loci

Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2+ breast cancer samples

Vasmatzis, G., Wang, X., Smadbeck, J., Murphy, S. J., Geiersbach, K. B., Johnson, S. H., Gaitatzes, A. G., Asmann, Y., Kosari, F., Borad, M. J., Serie, D. J., McLaughlin, S. A., Kachergus, J. M., Necela, B. M. & Thompson, E. A., Jul 13 2018, In : BMC Cancer. 18, 1, 738.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 8
Breast Neoplasms
Chromosomes, Human, Pair 17
Transcriptome
Genome
7 Citations (Scopus)
Paraproteinemias
Multiple Myeloma
Precision Medicine
Genetic Predisposition to Disease
Cytogenetics
3 Citations (Scopus)

Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

Allen, M., Wang, X., Serie, D. J., Strickland, S. L., Burgess, J. D., Koga, S., Younkin, C. S., Nguyen, T. T., Malphrus, K. G., Lincoln, S. J., Alamprese, M., Zhu, K., Chang, R., Carrasquillo, M. M., Kouri, N., Murray, M. E., Reddy, J. S., Funk, C., Price, N. D., Golde, T. E. & 5 others, Younkin, S. G., Asmann, Y., Crook, J., Dickson, D. W. & Taner, N., Jan 1 2018, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Gene Expression
Brain
Pathology
Coiled Bodies
6 Citations (Scopus)

Human Pegivirus infection and lymphoma risk and prognosis: A North American study

Fama, A., Xiang, J., Link, B. K., Allmer, C., Klinzman, D., Feldman, A. L., Nowakowski, G. S., Liebow, M., Larson, M. C., Maurer, M. J., Ansell, S. M., Novak, A. J., Asmann, Y., Slager, S. L., Call, T. G., Habermann, T. M., Cerhan, J. R. & Stapleton, J. T., Jan 1 2018, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

Lymphoma
Infection
Viremia
B-Cell Chronic Lymphocytic Leukemia
Confidence Intervals

Identification of missing variants by combining multiple analytic pipelines

Ren, Y., Reddy, J. S., Pottier, C., Sarangi, V., Tian, S., Sinnwell, J. P., McDonnell, S. K., Biernacka, J. M., Carrasquillo, M. M., Ross, O. A., Taner, N., Rademakers, R. V., Hudson, M., Mainzer, L. S. & Asmann, Y., Apr 16 2018, In : BMC Bioinformatics. 19, 1, 139.

Research output: Contribution to journalArticle

Sample Size
Pipelines
Gene Frequency
Alzheimer Disease
Sequencing
1 Citation (Scopus)

Loss of TNFAIP3 enhances MYD88L265P-driven signaling in non-Hodgkin lymphoma

Wenzl, K., Manske, M. K., Sarangi, V., Asmann, Y., Greipp, P. T., Schoon, H. R., Braggio, E. D., Maurer, M. J., Feldman, A. L., Witzig, T. E., Slager, S. L., Ansell, S. M., Cerhan, J. R. & Novak, A. J., Oct 1 2018, In : Blood Cancer Journal. 8, 10, 97.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Lymphoma, Large B-Cell, Diffuse
Non-Hodgkin's Lymphoma
Mutation
Up-Regulation
2 Citations (Scopus)

PCNT point mutations and familial intracranial aneurysms

Lorenzo-Betancor, O., Blackburn, P. R., Edwards, E., Vázquez-do-Campo, R., Klee, E. W., Labbé, C., Hodges, K., Glover, P., Sigafoos, A. N., Soto, A. I., Walton, R. L., Doxsey, S., Bober, M. B., Jennings, S., Clark, K. J., Asmann, Y., Miller, D., Freeman, W. D., Meschia, J. F. & Ross, O. A., Dec 4 2018, In : Neurology. 91, 23, p. e2170-e2181

Research output: Contribution to journalArticle

Intracranial Aneurysm
Subarachnoid Hemorrhage
Point Mutation
Intracranial Hemorrhages
Exome
5 Citations (Scopus)

Targetable fusions of the FRK tyrosine kinase in ALKnegative anaplastic large cell lymphoma

Hu, G., Dasari, S., Asmann, Y., Greipp, P. T., Knudson, R. A., Benson, H. K., Li, Y., Eckloff, B. W., Jen, J., Link, B. K., Jiang, L., Sidhu, J. S., Wellik, L. E., Witzig, T. E., Bennani, N., Cerhan, J. R., Luchtel, R. & Feldman, A. L., Feb 1 2018, In : Leukemia. 32, 2, p. 565-569 5 p.

Research output: Contribution to journalLetter

Anaplastic Large-Cell Lymphoma
Protein-Tyrosine Kinases
1 Citation (Scopus)

TMEM106B haplotypes have distinct gene expression patterns in aged brain

Ren, Y., Van Blitterswijk, M., Allen, M., Carrasquillo, M. M., Reddy, J. S., Wang, X., Beach, T. G., Dickson, D. W., Taner, N., Asmann, Y. & Rademakers, R. V., Jul 3 2018, In : Molecular Neurodegeneration. 13, 1, 35.

Research output: Contribution to journalArticle

Haplotypes
Temporal Lobe
Gene Expression
Cerebellum
Brain
2017
4 Citations (Scopus)

Abnormal expression of homeobox genes and transthyretin in C9ORF72 expansion carriers

Finch, N. A., Wang, X., Baker, M. C., Heckman, M. G., Gendron, T. D., Bieniek, K. F., Wuu, J., Dejesus-Hernandez, M., Brown, P. H., Chew, J., Jansen-West, K. R., Daughrity, L. M., Nicholson, A. M., Murray, M. E., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Petrucelli, L., Boeve, B. F. & 8 others, Graff Radford, N. R., Asmann, Y., Dickson, D. W., Benatar, M., Bowser, R., Boylan, K. B., Rademakers, R. V. & Van Blitterswijk, M., Jan 1 2017, In : Neurology: Genetics. 3, 4

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Prealbumin
Homeobox Genes
Open Reading Frames
Up-Regulation
4 Citations (Scopus)

African American exome sequencing identifies potential risk variants at Alzheimer disease loci

N'songo, A., Carrasquillo, M. M., Wang, X., Burgess, J. D., Nguyen, T., Asmann, Y., Serie, D. J., Younkin, S. G., Allen, M., Pedraza, O. D., Duara, R., Custo, M. T. G., Graff Radford, N. R. & Taner, N., Jan 1 2017, In : Neurology: Genetics. 3, 2, e141.

Research output: Contribution to journalArticle

Exome
African Americans
Alzheimer Disease
Genome-Wide Association Study
Endophenotypes
25 Citations (Scopus)

BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma

Parasramka, M., Yan, I. K., Wang, X., Nguyen, P., Matsuda, A., Maji, S., Foye, C., Asmann, Y. & Patel, T. C., Jan 25 2017, In : Molecular Cancer. 16, 1, 22.

Research output: Contribution to journalArticle

gemcitabine
Long Noncoding RNA
Cholangiocarcinoma
Proteins
Neoplasms
7 Citations (Scopus)

Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling

Kourtidis, A., Necela, B., Lin, W. H., Lu, R., Feathers, R. W., Asmann, Y., Thompson, E. A. & Anastasiadis, P. Z., Oct 1 2017, In : Journal of Cell Biology. 216, 10, p. 3073-3085 13 p.

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
Adherens Junctions
Cadherins
Epithelial Cells
Messenger RNA
1 Citation (Scopus)

Comprehensive genomic profiling of a rare thyroid follicular dendritic cell sarcoma

Davila, J. I., Starr, J. S., Attia, S., Wang, C., Knudson, R. A., Necela, B. M., Sarangi, V., Sun, Z. D., Ren, Y., Casler, J. D., Menke, D. M., Oliver, G. R., Joseph, R. W., Copland, J. A. III., Parker, A., Kocher, J-P., Thompson, E. A., Smallridge, R. C. & Asmann, Y., Sep 15 2017, In : Rare Tumors. 9, 2, p. 50-53 4 p., 6834.

Research output: Contribution to journalArticle

Follicular Dendritic Cell Sarcoma
Missense Mutation
Mutation
Gene Fusion
Neoplasms
1 Citation (Scopus)

Comprehensive Screening for Disease Risk Variants in Early-Onset Alzheimer's Disease Genes in African Americans Identifies Novel PSEN Variants

N'Songo, A., Carrasquillo, M. M., Wang, X., Nguyen, T., Asmann, Y., Younkin, S. G., Allen, M., Duara, R., Custo, M. T. G., Graff Radford, N. R. & Taner, N., 2017, In : Journal of Alzheimer's Disease. 56, 4, p. 1215-1222 8 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Genes
Exome
Population
8 Citations (Scopus)

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

Allen, M., Wang, X., Burgess, J. D., Watzlawik, J., Serie, D. J., Younkin, C. S., Nguyen, T., Malphrus, K. G., Lincoln, S., Carrasquillo, M. M., Ho, C., Chakrabarty, P., Strickland, S., Murray, M. E., Swarup, V., Geschwind, D. H., Seyfried, N. T., Dammer, E. B., Lah, J. J., Levey, A. I. & 11 others, Golde, T. E., Funk, C., Li, H., Price, N. D., Petersen, R. C., Graff Radford, N. R., Younkin, S. G., Dickson, D. W., Crook, J., Asmann, Y. & Taner, N., Jan 1 2017, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Alzheimer Disease
Brain
Temporal Lobe
Gene Regulatory Networks

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Holst, F., Hoivik, E. A., Gibson, W. J., Taylor-Weiner, A., Schumacher, S. E., Asmann, Y., Grossmann, P., Trovik, J., Necela, B. M., Thompson, E. A., Meyerson, M., Beroukhim, R., Salvesen, H. B. & Cherniack, A. D., Jun 30 2017, In : Scientific Reports. 7, 1 p.

Research output: Contribution to journalComment/debate

Endometrial Neoplasms
Growth Hormone
Hormones
corrigendum
8 Citations (Scopus)

Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial

Serie, D. J., Crook, J., Necela, B. M., Dockter, T. J., Wang, X., Asmann, Y., Fairweather, D., Bruno, K. A., Colon-Otero, G., Perez, E. A., Thompson, E. A. & Norton, N., 2017, In : Pharmacogenetics and Genomics. 27, 10, p. 378-385 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Stroke Volume
Paclitaxel
Anthracyclines
25 Citations (Scopus)

High somatic mutation and neoantigen burden are correlated with decreased progression-free survival in multiple myeloma

MMRF CoMMpass Network, Sep 22 2017, In : Blood Cancer Journal. 7, 9, p. e612

Research output: Contribution to journalArticle

Multiple Myeloma
Disease-Free Survival
Mutation
Missense Mutation
Standard of Care
21 Citations (Scopus)

In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers

DeJesus-Hernandez, M., Finch, N. C. A., Wang, X., Gendron, T. D., Bieniek, K. F., Heckman, M. G., Vasilevich, A., Murray, M. E., Rousseau, L., Weesner, R., Lucido, A., Parsons, M., Chew, J., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Boeve, B. F., Graff Radford, N. R., de Boer, J. & 6 others, Asmann, Y., Petrucelli, L., Boylan, K. B., Dickson, D. W., Van Blitterswijk, M. & Rademakers, R. V., May 15 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-15 15 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Open Reading Frames
Antisense RNA
RNA
Dipeptides
19 Citations (Scopus)

Lipocalin-2 protects the brain during inflammatory conditions

Kang, S., Ren, Y., Liu, C-C., Kurti, A., Baker, K. E., Bu, G. D., Asmann, Y. & Fryer, J. D., Jan 10 2017, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Lipopolysaccharides
Central Nervous System
Brain
Cytokines
Sepsis
7 Citations (Scopus)

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes

DeRycke, M. S., Gunawardena, S., Balcom, J. R., Pickart, A. M., Waltman, L. A., French, A. J., McDonnell, S., Riska, S. M., Fogarty, Z. C., Larson, M. C., Middha, S., Eckloff, B. W., Asmann, Y., Ferber, M. J., Haile, R. W., Gallinger, S., Clendenning, M., Rosty, C., Win, A. K., Buchanan, D. D. & 6 others, Hopper, J. L., Newcomb, P. A., Le Marchand, L., Goode, E. L., Lindor, N. M. & Thibodeau, S. N., Jan 1 2017, In : Molecular Genetics and Genomic Medicine. 5, 5, p. 553-569 17 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Colorectal Neoplasms
DNA Mismatch Repair
Genes
Mutation
10 Citations (Scopus)
Waldenstrom Macroglobulinemia
Up-Regulation
Mutation
Therapeutics
Phosphatidylinositol 3-Kinases
4 Citations (Scopus)
Exome
Lymphoma, Large B-Cell, Diffuse
2016
18 Citations (Scopus)

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Carrasquillo, M. M., Allen, M., Burgess, J. D., Wang, X., Strickland, S. L., Aryal, S., Siuda, J., Kachadoorian, M. L., Medway, C., Younkin, C. S., Nair, A., Wang, C., Chanana, P., Serie, D., Nguyen, T., Lincoln, S., Malphrus, K. G., Morgan, K., Golde, T. E., Price, N. D. & 10 others, White, C. C., De Jager, P. L., Bennett, D. A., Asmann, Y., Crook, J., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Multigene Family
Alzheimer Disease
Quantitative Trait Loci
Gene Expression
Meta-Analysis
7 Citations (Scopus)

Circulating Extracellular RNA Markers of Liver Regeneration

Yan, I. K., Wang, X., Asmann, Y., Haga, H. & Patel, T. C., Jul 1 2016, In : PLoS One. 11, 7, e0155888.

Research output: Contribution to journalArticle

liver regeneration
Liver Regeneration
Liver
Hepatectomy
RNA

Erratum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth (Scientific Reports (2016) 6 (25521) DOI: 10.1038/srep25521)

Holst, F., Hoivik, E. A., Gibson, W. J., Taylor-Weiner, A., Schumacher, S. E., Asmann, Y., Grossmann, P., Trovik, J., Necela, B. M., Thompson, E. A., Meyerson, M., Beroukhim, R., Salvesen, H. B. & Cherniack, A. D., Jun 24 2016, In : Scientific Reports. 6, 27960.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Demchenko, Y., Roschke, A., Chen, W. D., Asmann, Y., Bergsagel, P. L. & Kuehl, W. M., Sep 30 2016, In : Nucleic Acids Research. 44, 17, p. 8189-8198 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Comparative Genomic Hybridization
Tumor Cell Line
Eukaryota
Oncogenes
18 Citations (Scopus)

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci

Allen, M., Burgess, J. D., Ballard, T., Serie, D., Wang, X., Younkin, C. S., Sun, Z. D., Kouri, N., Baheti, S., Wang, C., Carrasquillo, M. M., Nguyen, T., Lincoln, S., Malphrus, K., Murray, M. E., Golde, T. E., Price, N. D., Younkin, S. G., Schellenberg, G. D., Asmann, Y. & 4 others, Ordog, T., Crook, J., Dickson, D. W. & Taner, N., Apr 26 2016, (Accepted/In press) In : Acta Neuropathologica. p. 1-15 15 p.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Methylation
Gene Expression
Coiled Bodies
Single Nucleotide Polymorphism
24 Citations (Scopus)

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Machiela, M. J., Lan, Q., Slager, S. L., Vermeulen, R. C. H., Teras, L. R., Camp, N. J., Cerhan, J. R., Spinelli, J. J., Wang, S. S., Nieters, A., Vijai, J., Yeager, M., Wang, Z., Ghesquières, H., McKay, J., Conde, L., de Bakker, P. I. W., Cox, D. G., Burdett, L., Monnereau, A. & 100 others, Flowers, C. R., De Roos, A. J., Brooks-Wilson, A. R., Giles, G. G., Melbye, M., Gu, J., Jackson, R. D., Kane, E., Purdue, M. P., Vajdic, C. M., Albanes, D., Kelly, R. S., Zucca, M., Bertrand, K. A., Zeleniuch-Jacquotte, A., Lawrence, C., Hutchinson, A., Zhi, D., Habermann, T. M., Link, B. K., Novak, A. J., Dogan, A., Asmann, Y., Liebow, M., Thompson, C. A., Ansell, S. M., Witzig, T. E., Tilly, H., Haioun, C., Molina, T. J., Hjalgrim, H., Glimelius, B., Adami, H. O., Roos, G., Bracci, P. M., Riby, J., Smith, M. T., Holly, E. A., Cozen, W., Hartge, P., Morton, L. M., Severson, R. K., Tinker, L. F., North, K. E., Becker, N., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., Staines, A., Lightfoot, T., Crouch, S., Smith, A., Roman, E., Ryan Diver, W., Offit, K., Zelenetz, A., Klein, R. J., Villano, D. J., Zheng, T., Zhang, Y., Holford, T. R., Turner, J., Southey, M. C., Clavel, J., Virtamo, J., Weinstein, S., Riboli, E., Vineis, P., Kaaks, R., Boeing, H., Tjønneland, A., Angelucci, E., Di Lollo, S., Rais, M., De Vivo, I., Giovannucci, E., Kraft, P., Huang, J., Ma, B., Ye, Y., Chiu, B. C. H., Liang, L., Park, J. H., Chung, C. C., Weisenburger, D. D., Fraumeni, J. F., Salles, G., Glenn, M., Cannon-Albright, L., Curtin, K., Wu, X., Smedby, K. E., de Sanjose, S., Skibola, C. F., Berndt, S. I., Birmann, B. M., Chanock, S. J. & Rothman, N., Apr 15 2016, In : Human Molecular Genetics. 25, 8, p. 1663-1676 14 p., ddw027.

Research output: Contribution to journalArticle

Telomere
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
32 Citations (Scopus)

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Allen, M., Carrasquillo, M. M., Funk, C., Heavner, B. D., Zou, F., Younkin, C. S., Burgess, J. D., Chai, H. S., Crook, J., Eddy, J. A., Li, H., Logsdon, B., Peters, M. A., Dang, K. K., Wang, X., Serie, D., Wang, C., Nguyen, T., Lincoln, S., Malphrus, K. & 11 others, Bisceglio, G., Li, M., Golde, T. E., Mangravite, L. M., Asmann, Y., Price, N. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Oct 11 2016, In : Scientific data. 3, 160089.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Genotype
Brain
Genome
Genes
51 Citations (Scopus)

IAP antagonists induce anti-tumor immunity in multiple myeloma

Chesi, M., Mirza, N. N., Garbitt, V. M., Sharik, M. E., Dueck, A., Asmann, Y., Akhmetzyanova, I., Kosiorek, H. E., Calcinotto, A., Riggs, D. L., Keane, N., Ahmann, G. J., Morrison, K. M., Fonseca, R., Lacy, M., Dingli, D. M., Kumar, S. K., Ailawadhi, S., Dispenzieri, A., Buadi, F. & 7 others, Gertz, M., Reeder, C. B., Lin, Y., Chanan Khan, A. A., Stewart, A. K., Fooksman, D. & Bergsagel, P. L., Dec 1 2016, In : Nature Medicine. 22, 12, p. 1411-1420 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Tumors
Immunity
Apoptosis
Neoplasms
43 Citations (Scopus)

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Luchtel, R., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
RNA Sequence Analysis
T-cells
Gene Fusion
Fusion reactions
10 Citations (Scopus)

Jak1-STAT3 signals are essential effectors of the USP6/TRE17 oncogene in tumorigenesis

Quick, L., Young, R., Henrich, I. C., Wang, X., Asmann, Y., Oliveira, A. M. & Chou, M. M., Sep 15 2016, In : Cancer Research. 76, 18, p. 5337-5347 11 p.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
Oncogenes
Carcinogenesis
Fasciitis
Aneurysmal Bone Cysts
3 Citations (Scopus)

PPP6R3-USP6 amplification: Novel oncogenic mechanism in malignant nodular fasciitis

Guo, R., Wang, X., Chou, M. M., Asmann, Y., Wenger, D. E., Al-Ibraheemi, A., Molavi, D. W., Aboulafia, A., Jin, L., Fritchie, K., Oliveira, J., Jenkins, R. B., Westendorf, J. J., Dong, J. & Oliveira, A. M., Aug 1 2016, In : Genes Chromosomes and Cancer. 55, 8, p. 640-649 10 p.

Research output: Contribution to journalArticle

Fasciitis
Gene Fusion
Peptide Hydrolases
Up-Regulation
Recurrence
6 Citations (Scopus)

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Holst, F., Hoivik, E. A., Gibson, W. J., Taylor-Weiner, A., Schumacher, S. E., Asmann, Y., Grossmann, P., Trovik, J., Necela, B. M., Thompson, E. A., Meyerson, M., Beroukhim, R., Salvesen, H. B. & Cherniack, A. D., May 10 2016, In : Scientific Reports. 6, 25521.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Growth Hormone
Estrogen Receptor alpha
Hormones
Breast Neoplasms
28 Citations (Scopus)

TYROBP genetic variants in early-onset Alzheimer's disease

Pottier, C., Ravenscroft, T. A., Brown, P. H., Finch, N. C. A., Baker, M., Parsons, M., Asmann, Y., Ren, Y., Christopher, E., Levitch, D., Van Blitterswijk, M., Cruchaga, C., Campion, D., Nicolas, G., Richard, A. C., Guerreiro, R., Bras, J. T., Zuchner, S., Gonzalez, M. A., Bu, G. D. & 10 others, Younkin, S. G., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Taner, N., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., Dec 1 2016, In : Neurobiology of Aging. 48, p. 222.e9-222.e15

Research output: Contribution to journalArticle

Alzheimer Disease
Genes
Exome
Age of Onset
Mutation
2 Citations (Scopus)

Validation of Gene Expression Signatures to Identify Low-risk Clear-cell Renal Cell Carcinoma Patients at Higher Risk for Disease-related Death

Parasramka, M., Serie, D. J., Asmann, Y., Eckel-Passow, J. E., Castle, E. P., Stanton, M. L., Leibovich, B. C., Thompson, R. H., Thompson, E. A., Parker, A., Ho, T. H. & Joseph, R. W., Dec 15 2016, In : European Urology Focus. 2, 6, p. 608-615 8 p.

Research output: Contribution to journalArticle

Transcriptome
Renal Cell Carcinoma
Genes
Paraffin
Formaldehyde
2015
23 Citations (Scopus)

Common oncogene mutations and novel SND1-BRAF transcript fusion in lung adenocarcinoma from never smokers

Jang, J. S., Lee, A., Li, J., Liyanage, H., Yang, Y. D., Guo, L., Asmann, Y., Li, P. W., Erickson-Johnson, M., Sakai, Y., Sun, Z. D., Jeon, H. S., Hwang, H., Bungum, A. O., Edell, E., Simon, V. A., Kopp, K. J., Eckloff, B., Oliveira, A. M., Wieben, E. D. & 6 others, Aubry, M. C., Yi, E., Wigle, D. A., Diasio, R. B., Yang, P. & Jen, J., May 18 2015, In : Scientific Reports. 5, 9755.

Research output: Contribution to journalArticle

Oncogenes
Mutation
Exons
Lung Neoplasms
Neoplasms
8 Citations (Scopus)

Expression of polarity genes in human cancer

Lin, W. H., Asmann, Y. & Anastasiadis, P. Z., Mar 30 2015, In : Cancer Informatics. 14, p. 15-28 14 p.

Research output: Contribution to journalArticle

Gene Expression
Neoplasms
Transcriptome
Proteins
Genomics
69 Citations (Scopus)

Genome-wide analysis uncovers novel recurrent alterations in primary central nervous system lymphomas

Braggio, E. D., Van Wier, S., Ojha, J., McPhail, E., Asmann, Y., Egan, J., Da Silva, J. A., Schiff, D., Lopes, M. B., Decker, P. A., Valdez, R., Tibes, R., Eckloff, B., Witzig, T. E., Stewart, A. K., Fonseca, R. & O'Neill, B. P., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3986-3994 9 p.

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Genome
Lymphoma, Large B-Cell, Diffuse
Exome
11 Citations (Scopus)

Genome-Wide association study of event-free survival in diffuse large B-cell lymphoma treated with immunochemotherapy

Ghesquieres, H., Slager, S. L., Jardin, F., Veron, A. S., Asmann, Y., Maurer, M. J., Fest, T., Habermann, T. M., Bene, M. C., Novak, A. J., Mareschal, S., Haioun, C., Lamy, T., Ansell, S. M., Tilly, H., Witzig, T. E., Weiner, G. J., Feldman, A. L., Dogan, A., Cunningham, J. M. & 7 others, Olswold, C. L., Molina, T. J., Link, B. K., Milpied, N., Cox, D. G., Salles, G. A. & Cerhan, J. R., Nov 20 2015, In : Journal of Clinical Oncology. 33, 33, p. 3930-3937 8 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Genome-Wide Association Study
Disease-Free Survival
Single Nucleotide Polymorphism
Survival