Y S Betty Kim, MD, PhD

  • 4414 Citations
  • 19 Scopus h-Index
20012020

Research output per year

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Research Output

  • 4414 Citations
  • 19 Scopus h-Index
  • 32 Article
  • 11 Review article
  • 2 Comment/debate
  • 2 Letter
2020

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Yang, Z., Shi, J., Xie, J., Wang, Y., Sun, J., Liu, T., Zhao, Y., Zhao, X., Wang, X., Ma, Y., Malkoc, V., Chiang, C., Deng, W., Chen, Y., Fu, Y., Kwak, K. J., Fan, Y., Kang, C., Yin, C., Rhee, J. & 9 others, Bertani, P., Otero, J., Lu, W., Yun, K., Lee, A. S., Jiang, W., Teng, L., Kim, B. Y. S. & Lee, L. J., Jan 1 2020, In : Nature Biomedical Engineering. 4, 1, p. 69-83 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Low-dose anti-angiogenic therapy sensitizes breast cancer to PD-1 blockade

Li, Q., Wang, Y., Jia, W., Deng, H., Li, G., Deng, W., Chen, J., Kim, B. Y. S., Jiang, W., Liu, Q. & Liu, J., Apr 1 2020, In : Clinical Cancer Research. 26, 7, p. 1712-1724 13 p.

Research output: Contribution to journalArticle

Nanotechnology platforms for cancer immunotherapy

Yang, Z., Ma, Y., Zhao, H., Yuan, Y. & Kim, B. Y. S., Mar 1 2020, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 12, 2, e1590.

Research output: Contribution to journalReview article

6 Scopus citations

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

von Roemeling, C. A., Wang, Y., Qie, Y., Yuan, H., Zhao, H., Liu, X., Yang, Z., Yang, M., Deng, W., Bruno, K. A., Chan, C. K., Lee, A. S., Rosenfeld, S. S., Yun, K., Johnson, A. J., Mitchell, D. A., Jiang, W. & Kim, B. Y. S., Dec 1 2020, In : Nature communications. 11, 1, 1508.

Research output: Contribution to journalArticle

Open Access
2019

Folate receptor-targeted albumin nanoparticles based on microfluidic technology to deliver cabazitaxel

Meng, F., Sun, Y., Lee, R. J., Wang, G., Zheng, X., Zhang, H., Fu, Y., Yan, G., Wang, Y., Deng, W., Parks, E., Kim, B. Y. S., Yang, Z., Jiang, W. & Teng, L., Oct 2019, In : Cancers. 11, 10, 1571.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Membrane TLR9 positive neutrophil mediated MPLA protects against fatal bacterial sepsis

Yang, Z., Wang, L., Yu, H., Wang, R., Gou, Y., Zhang, M. M., Kang, C., Liu, T., Lan, Y., Wang, X., Liu, J., Cooper, M. A., Li, X., Yue, K., Yu, Y., Wang, L., Kim, B. Y. S., Jiang, W. & Sun, W., Jan 1 2019, In : Theranostics. 9, 21, p. 6269-6283 15 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

On the issue of transparency and reproducibility in nanomedicine

Leong, H. S., Butler, K. S., Brinker, C. J., Azzawi, M., Conlan, S., Dufés, C., Owen, A., Rannard, S., Scott, C., Chen, C., Dobrovolskaia, M. A., Kozlov, S. V., Prina-Mello, A., Schmid, R., Wick, P., Caputo, F., Boisseau, P., Crist, R. M., McNeil, S. E., Fadeel, B. & 58 others, Tran, L., Hansen, S. F., Hartmann, N. B., Clausen, L. P. W., Skjolding, L. M., Baun, A., Ågerstrand, M., Gu, Z., Lamprou, D. A., Hoskins, C., Huang, L., Song, W., Cao, H., Liu, X., Jandt, K. D., Jiang, W., Kim, B. Y. S., Wheeler, K. E., Chetwynd, A. J., Lynch, I., Moghimi, S. M., Nel, A., Xia, T., Weiss, P. S., Sarmento, B., das Neves, J., Santos, H. A., Santos, L., Mitragotri, S., Little, S., Peer, D., Amiji, M. M., Alonso, M. J., Petri-Fink, A., Balog, S., Lee, A., Drasler, B., Rothen-Rutishauser, B., Wilhelm, S., Acar, H., Harrison, R. G., Mao, C., Mukherjee, P., Ramesh, R., McNally, L. R., Busatto, S., Wolfram, J., Bergese, P., Ferrari, M., Fang, R. H., Zhang, L., Zheng, J., Peng, C., Du, B., Yu, M., Charron, D. M., Zheng, G. & Pastore, C., Jul 1 2019, In : Nature Nanotechnology. 14, 7, p. 629-635 7 p.

Research output: Contribution to journalLetter

23 Scopus citations

Phagocytosis checkpoints as new targets for cancer immunotherapy

Feng, M., Jiang, W., Kim, B. Y. S., Zhang, C. C., Fu, Y. X. & Weissman, I. L., Oct 1 2019, In : Nature Reviews Cancer. 19, 10, p. 568-586 19 p.

Research output: Contribution to journalReview article

18 Scopus citations

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9)

Leong, H. S., Butler, K. S., Brinker, C. J., Azzawi, M., Conlan, S., Dufès, C., Owen, A., Rannard, S., Scott, C., Chen, C., Dobrovolskaia, M. A., Kozlov, S. V., Prina-Mello, A., Schmid, R., Wick, P., Caputo, F., Boisseau, P., Crist, R. M., McNeil, S. E., Fadeel, B. & 58 others, Tran, L., Hansen, S. F., Hartmann, N. B., Clausen, L. P. W., Skjolding, L. M., Baun, A., Ågerstrand, M., Gu, Z., Lamprou, D. A., Hoskins, C., Huang, L., Song, W., Cao, H., Liu, X., Jandt, K. D., Jiang, W., Kim, B. Y. S., Wheeler, K. E., Chetwynd, A. J., Lynch, I., Moghimi, S. M., Nel, A., Xia, T., Weiss, P. S., Sarmento, B., Neves, J. D., Santos, H. A., Santos, L., Mitragotri, S., Little, S., Peer, D., Amiji, M. M., Alonso, M. J., Petri-Fink, A., Balog, S., Lee, A., Drasler, B., Rothen-Rutishauser, B., Wilhelm, S., Acar, H., Harrison, R. G., Mao, C., Mukherjee, P., Ramesh, R., McNally, L. R., Busatto, S., Wolfram, J., Bergese, P., Ferrari, M., Fang, R. H., Zhang, L., Zheng, J., Peng, C., Du, B., Yu, M., Charron, D. M., Zheng, G. & Pastore, C., Aug 1 2019, In : Nature Nanotechnology. 14, 8, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9)

Leong, H. S., Butler, K. S., Brinker, C. J., Azzawi, M., Conlan, S., Dufès, C., Owen, A., Rannard, S., Scott, C., Chen, C., Dobrovolskaia, M. A., Kozlov, S. V., Prina-Mello, A., Schmid, R., Wick, P., Caputo, F., Boisseau, P., Crist, R. M., McNeil, S. E., Fadeel, B. & 58 others, Tran, L., Hansen, S. F., Hartmann, N. B., Clausen, L. P. W., Skjolding, L. M., Baun, A., Ågerstrand, M., Gu, Z., Lamprou, D. A., Hoskins, C., Huang, L., Song, W., Cao, H., Liu, X., Jandt, K. D., Jiang, W., Kim, B. Y. S., Wheeler, K. E., Chetwynd, A. J., Lynch, I., Moghimi, S. M., Nel, A., Xia, T., Weiss, P. S., Sarmento, B., das Neves, J., Santos, H. A., Santos, L., Mitragotri, S., Little, S., Peer, D., Amiji, M. M., Alonso, M. J., Petri-Fink, A., Balog, S., Lee, A., Drasler, B., Rothen-Rutishauser, B., Wilhelm, S., Acar, H., Harrison, R. G., Mao, C., Mukherjee, P., Ramesh, R., McNally, L. R., Busatto, S., Wolfram, J., Bergese, P., Ferrari, M., Fang, R. H., Zhang, L., Zheng, J., Peng, C., Du, B., Yu, M., Charron, D. M., Zheng, G. & Pastore, C., Sep 1 2019, In : Nature Nanotechnology. 14, 9, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery

Chen, Y., Liu, X., Yuan, H., Yang, Z., von Roemeling, C. A., Qie, Y., Zhao, H., Wang, Y., Jiang, W. & Kim, Y. S. B., Jan 1 2019, (Accepted/In press) In : Advanced Science. 1802070.

Research output: Contribution to journalArticle

18 Scopus citations

The reciprocity between radiotherapy and cancer immunotherapy

Wang, Y., Liu, Z. G., Yuan, H., Deng, W., Li, J., Huang, Y., Kim, B. Y. S., Story, M. D. & Jiang, W., Jan 1 2019, In : Clinical Cancer Research. 25, 6, p. 1709-1717 9 p.

Research output: Contribution to journalReview article

7 Scopus citations

Tumor Vasculatures: A New Target for Cancer Immunotherapy

Liu, Z., Wang, Y., Huang, Y., Kim, Y. S. B., Shan, H., Wu, D. & Jiang, W., Jan 1 2019, In : Trends in Pharmacological Sciences.

Research output: Contribution to journalReview article

6 Scopus citations

Visualization of Hepatocellular Regeneration in Mice After Partial Hepatectomy

Chen, Y., Hata, T., Rehman, F., Kang, L., Yang, L., Kim, Y. S. B. & Nguyen, J. H., Mar 1 2019, In : Journal of Surgical Research. 235, p. 494-500 7 p.

Research output: Contribution to journalArticle

2018

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

von Roemeling, C. A., Caulfield, T. R., Marlow, L., Bok, I., Wen, J., Miller, J. L., Hughes, R., Hazlehurst, L., Pinkerton, A. B., Radisky, D. C., Tun, H. W., Kim, Y. S. B., Lane, A. L. & Copland, J. A., Jan 1 2018, In : Oncotarget. 9, 1, p. 3-20 18 p.

Research output: Contribution to journalArticle

7 Scopus citations

How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation

Ioannidis, J. P. A., Kim, Y. S. B. & Trounson, A., Nov 1 2018, In : Nature Biomedical Engineering. 2, 11, p. 797-809 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Immunomodulating nanomedicine for cancer therapy

Liu, Z., Jiang, W., Nam, J., Moon, J. J. & Kim, Y. S. B., Jan 1 2018, (Accepted/In press) In : Nano Letters.

Research output: Contribution to journalArticle

22 Scopus citations

Improving immune-vascular crosstalk for cancer immunotherapy

Huang, Y., Kim, B. Y. S., Chan, C. K., Hahn, S. M., Weissman, I. L. & Jiang, W., Mar 1 2018, In : Nature Reviews Immunology. 18, 3, p. 195-203 9 p.

Research output: Contribution to journalReview article

58 Scopus citations

Increased vessel perfusion predicts the efficacy of immune checkpoint blockade

Zheng, X., Fang, Z., Liu, X., Deng, S., Zhou, P., Wang, X., Zhang, C., Yin, R., Hu, H., Chen, X., Han, Y., Zhao, Y., Lin, S. H., Qin, S., Wang, X., Kim, Y. S. B., Zhou, P., Jiang, W., Wu, Q. & Huang, Y., May 1 2018, In : Journal of Clinical Investigation. 128, 5, p. 2104-2115 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Perspectives of Nanotechnology in the Management of Gliomas

Yoon, J. W., Jiang, W., Rutka, J. T., Huang, Y. & Kim, Y. S. B., Jan 1 2018, In : Progress in neurological surgery. 32, p. 196-210 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Study of osteocyte behavior by high-resolution intravital imaging following photo-induced ischemia

Yuan, H., Jiang, W., Chen, Y. & Kim, Y. S. B., Nov 4 2018, In : Molecules. 23, 11, 2874.

Research output: Contribution to journalArticle

2017

Breaking Down the Barriers to Precision Cancer Nanomedicine

von Roemeling, C., Jiang, W., Chan, C. K., Weissman, I. L. & Kim, B. Y. S., Feb 1 2017, In : Trends in Biotechnology. 35, 2, p. 159-171 13 p.

Research output: Contribution to journalReview article

100 Scopus citations

Designing nanomedicine for immuno-oncology

Jiang, W., Von Roemeling, C. A., Chen, Y., Qie, Y., Liu, X., Chen, J. & Kim, Y. S. B., Feb 10 2017, In : Nature Biomedical Engineering. 1, 2, 0029.

Research output: Contribution to journalArticle

81 Scopus citations

Lessons from immuno-oncology: A new era for cancer nanomedicine?

Jiang, W., Yuan, H., Chan, C. K., Von Roemeling, C. A., Yan, Z., Weissman, I. L. & Kim, B. Y. S., Jun 1 2017, In : Nature Reviews Drug Discovery. 16, 6, p. 369-370 2 p.

Research output: Contribution to journalReview article

15 Scopus citations

Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy

Yuan, H., Jiang, W., von Roemeling, C. A., Qie, Y., Liu, X., Chen, Y., Wang, Y., Wharen, R. E., Yun, K., Bu, G. D., Knutson, K. L. & Kim, Y. S. B., May 1 2017, (Accepted/In press) In : Nature Nanotechnology.

Research output: Contribution to journalArticle

46 Scopus citations

S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma

Chow, K. H., Park, H. J., George, J., Yamamoto, K., Gallup, A. D., Graber, J. H., Chen, Y., Jiang, W., Steindler, D. A., Neilson, E. G., Kim, Y. S. B. & Yun, K., Oct 1 2017, In : Cancer Research. 77, 19, p. 5360-5373 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

Stereotactic radiosurgery of early melanoma brain metastases after initiation of anti-CTL-4 treatment is associated with improved intracranial control

An, Y., Jiang, W., Kim, Y. S. B., Qian, J. M., Tang, C., Fang, P., Logan, J., D'Souza, N. M., Haydu, L. E., Wang, X. A., Hess, K. R., Kluger, H., Glitza, I. C., Mahajan, A., Welsh, J. W., Lin, S. H., Yu, J. B., Davies, M. A., Hwu, P., Sulman, E. P. & 3 others, Brown, P. D., Chiang, V. L. S. & Li, J., 2017, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

15 Scopus citations
2016

Cerebral Venous Thrombosis Associated with Intracranial Hemorrhage and Timing of Anticoagulation after Hemicraniectomy

Pizzi, M. A., Alejos, D. A., Siegel, J. L., Kim, Y. S. B., Miller, D. A. & Freeman, W. D., Sep 1 2016, In : Journal of Stroke and Cerebrovascular Diseases. 25, 9, p. 2312-2316 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immune Priming of the Tumor Microenvironment by Radiation

Jiang, W., Chan, C. K., Weissman, I. L., Kim, B. Y. S. & Hahn, S. M., Nov 1 2016, In : Trends in Cancer. 2, 11, p. 638-645 8 p.

Research output: Contribution to journalReview article

39 Scopus citations

Non-contiguous meningeal metastases of olfactory neuroblastoma

Jiang, W., Liu, J., Gullane, P. J., Gentili, F., Wharen, R. E., Kim, Y. S. B. & DeMonte, F., Jan 1 2016, In : Journal of Neuro-Oncology. 126, 1, p. 201-203 3 p.

Research output: Contribution to journalLetter

7 Scopus citations

Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma

Yushi, Q., Li, Z., Von Roemeling, C. A., Doeppler, H., Marlow, L. A., Kim, Y. S. B., Radisky, D. C., Storz, P., Copland, J. A. III. & Tun, H. W., May 31 2016, In : Oncotarget. 7, 22, p. 32156-32171 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prognostic value of p16 expression in Epstein-Barr virus-positive nasopharyngeal carcinomas

Jiang, W., Chamberlain, P. D., Garden, A. S., Kim, Y. S. B., Ma, D., Lo, E. J., Bell, D., Gunn, G. B., Fuller, C. D., Rosenthal, D. I., Beadle, B. M., Frank, S. J., Morrison, W. H., El-Naggar, A. K., Glisson, B. S., Sturgis, E. M. & Phan, J., Apr 1 2016, In : Head and Neck. 38, p. E1459-E1466

Research output: Contribution to journalArticle

13 Scopus citations

Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes

Qie, Y., Yuan, H., Von Roemeling, C. A., Chen, Y., Liu, X., Shih, K. D., Knight, J. A., Tun, H. W., Wharen, R. E., Jiang, W. & Kim, Y. S. B., May 19 2016, In : Scientific Reports. 6, 26269.

Research output: Contribution to journalArticle

51 Scopus citations

The role of elective nodal irradiation for esthesioneuroblastoma patients with clinically negative neck

Jiang, W., Mohamed, A. S. R., Fuller, C. D., Kim, Y. S. B., Tang, C., Gunn, G. B., Hanna, E. Y., Frank, S. J., Su, S. Y., Diaz, E., Kupferman, M. E., Beadle, B. M., Morrison, W. H., Skinner, H., Lai, S. Y., El-Naggar, A. K., DeMonte, F., Rosenthal, D. I., Garden, A. S. & Phan, J., Jul 1 2016, In : Practical Radiation Oncology. 6, 4, p. 241-247 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

The role of postmastectomy radiotherapy in clinically nodepositive, stage II-III breast cancer patients with pathological negative nodes after neoadjuvant chemotherapy: An analysis from the NCDB

Liu, J., Mao, K., Jiang, S., Jiang, W., Chen, K., Kim, Y. S. B., Liu, Q. & Jacobs, L. K., Apr 26 2016, In : Oncotarget. 7, 17, p. 24848-24859 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2015

Elevated risks of subsequent endometrial cancer development among breast cancer survivors with different hormone receptor status: a SEER analysis

Liu, J., Jiang, W., Mao, K., An, Y., Su, F., Kim, B. Y. S., Liu, Q. & Jacobs, L. K., Jan 1 2015, In : Breast Cancer Research and Treatment. 150, 2, p. 439-445 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Remodeling Tumor Vasculature to Enhance Delivery of Intermediate-Sized Nanoparticles

Jiang, W., Huang, Y., An, Y. & Kim, Y. S. B., Sep 22 2015, In : ACS Nano. 9, 9, p. 8689-8696 8 p.

Research output: Contribution to journalArticle

79 Scopus citations
2014

Diagnostic discrepancies in malignant astrocytoma due to limited small pathological tumor sample can be overcome by IDH1 testing

Kim, B. Y. S., Jiang, W., Beiko, J., Prabhu, S. S., Demonte, F., Gilbert, M. R., Sawaya, R., Aldape, K. D., Cahill, D. P. & McCutcheon, I. E., Jun 2014, In : Journal of neuro-oncology. 118, 2, p. 405-412 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Nanosurgical resection of malignant brain tumors: Beyond the cutting edge

Rutka, J. T., Kim, B., Etame, A. & Diaz, R. J., Oct 28 2014, In : ACS Nano. 8, 10, p. 9716-9722 7 p.

Research output: Contribution to journalReview article

12 Scopus citations
2012

Pazopanib therapy for cerebellar hemangioblastomas in von Hippel-Lindau disease

Kim, B. Y. S., Jonasch, E. & McCutcheon, I. E., Jun 1 2012, In : Targeted Oncology. 7, 2, p. 145-149 5 p.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Current concepts: Nanomedicine

Kim, B. Y. S., Rutka, J. T. & Chan, W. C. W., Dec 16 2010, In : New England Journal of Medicine. 363, 25, p. 2434-2443 10 p.

Research output: Contribution to journalReview article

619 Scopus citations
2008

Assessing Near-Infrared Quantum Dots for Deep Tissue, Organ, and Animal Imaging Applications

Jiang, W., Singhal, A., Kim, B. Y. S., Zheng, J., Rutka, J. T., Wang, C. & Chan, W. C. W., Feb 1 2008, In : JALA - Journal of the Association for Laboratory Automation. 13, 1, p. 6-12 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Biodegradable quantum dot nanocomposites enable live cell labeling and imaging of cytoplasmic targets

Kim, B. Y. S., Jiang, W., Oreopoulos, J., Yip, C. M., Rutka, J. T. & Chan, W. C. W., Nov 1 2008, In : Nano Letters. 8, 11, p. 3887-3892 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Nanoparticle-mediated cellular response is size-dependent

Jiang, W., Kim, B. Y. S., Rutka, J. T. & Chan, W. C. W., Mar 2008, In : Nature Nanotechnology. 3, 3, p. 145-150 6 p.

Research output: Contribution to journalArticle

1820 Scopus citations
2007

Advances and challenges of nanotechnology-based drug delivery systems

Jiang, W., Kim, B. Y. S., Rutka, J. T. & Chan, W. C. W., Nov 1 2007, In : Expert Opinion on Drug Delivery. 4, 6, p. 621-633 13 p.

Research output: Contribution to journalReview article

77 Scopus citations
2002

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

Zhu, S., Stavrovskaya, I. G., Drozda, M., Kim, B. Y. S., Ona, V., Li, M., Sarang, S., Liu, A. S., Hartley, D. M., Wu, D. C., Guilans, S., Ferrante, R. J., Przedborski, S., Kristal, B. S. & Friedlander, R. M., May 2 2002, In : Nature. 417, 6884, p. 74-78 5 p.

Research output: Contribution to journalArticle

919 Scopus citations
2001

Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma

Abounader, R., Ranganathan, S., Kim, B. Y. S., Nichols, C. & Laterra, J., Mar 19 2001, In : Journal of neurochemistry. 76, 5, p. 1497-1508 12 p.

Research output: Contribution to journalArticle

43 Scopus citations