Wolfgang Singer, MD

  • 2513 Citations
  • 28 Scopus h-Index
19992020

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Article

Abnormal vasoreaction to arousal stimuli - An early sign of diabetic sympathetic neuropathy demonstrated by laser Doppler flowmetry

Hilz, M. J., Hecht, M. J., Berghoff, M., Singer, W. & Neundoerfer, B., Jan 1 2000, In : Journal of Clinical Neurophysiology. 17, 4, p. 419-425 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Acetylcholinesterase inhibition: A novel approach in the treatment of neurogenic orthostatic hypotension

Singer, W., Opfer-Gehrking, T. L., McPhee, B. R., Hilz, M. J., Bharucha, A. E. & Low, P. A., Sep 1 2003, In : Journal of Neurology, Neurosurgery and Psychiatry. 74, 9, p. 1294-1298 5 p.

Research output: Contribution to journalArticle

128 Scopus citations

Acetylcholinesterase inhibition in patients with orthostatic intolerance

Singer, W., Opfer-Gehrking, T. L., Nickander, K. K., Hines, S. M. & Low, P. A., Oct 2006, In : Journal of Clinical Neurophysiology. 23, 5, p. 477-482 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

A critique of the second consensus criteria for multiple system atrophy

on behalf of the Movement Disorder Society Multiple System Atrophy Study Group, Jul 2019, In : Movement Disorders. 34, 7, p. 975-984 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Adrenergic and vagal baroreflex sensitivity in autonomic failure

Schrezenmaier, C., Singer, W., Swift, N. M., Sletten, D., Tanabe, J. & Low, P. A., Mar 2007, In : Archives of neurology. 64, 3, p. 381-386 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Alpha-Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body Synucleinopathies

Singer, W., Schmeichel, A. M., Shahnawaz, M., Schmelzer, J. D., Boeve, B. F., Sletten, D. M., Gehrking, T. L., Gehrking, J. A., Olson, A. D., Savica, R., Suarez, M. D., Soto, C. & Low, P. A., Sep 1 2020, In : Annals of neurology. 88, 3, p. 503-512 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

A middle-aged woman with nausea, weight loss, and orthostatic hypotension

Singer, W., Yung, I. O., Wollmann, R., Kelly, T. & Keegan, B. M., Aug 2 2011, In : Neurology. 77, 5, p. 489-495 7 p.

Research output: Contribution to journalArticle

Amyloid-like IgM deposition neuropathy: A distinct clinico-pathologic and proteomic profiled disorder

Figueroa, J. J., Bosch, E. P., Dyck, P. J. B., Singer, W., Vrana, J. A., Theis, J. D., Dogan, A. & Klein, C. J., Jun 2012, In : Journal of the Peripheral Nervous System. 17, 2, p. 182-190 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Anhidrosis in multiple system atrophy involves pre- and postganglionic sudomotor dysfunction

Coon, E. A., Fealey, R. D., Sletten, D. M., Mandrekar, J. N., Benarroch, E. E., Sandroni, P., Low, P. A. & Singer, W., Mar 1 2017, In : Movement Disorders. 32, 3, p. 397-404 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

A prospective, 1-year follow-up study of postural tachycardia syndrome

Kimpinski, K., Figueroa, J. J., Singer, W., Sletten, D. M., Iodice, V., Sandroni, P., Fischer, P. R., Opfer-Gehrking, T. L., Gehrking, J. A. & Low, P. A., Aug 2012, In : Mayo Clinic proceedings. 87, 8, p. 746-752 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

A report of the autonomic symptom profile in patients with fibromyalgia

Vincent, A., McAllister, S. J., Singer, W., Toussaint, L. L., Sletten, D. M., Whipple, M. O. & Low, P. A., Mar 2014, In : Journal of Clinical Rheumatology. 20, 2, p. 106-108 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Association study between multiple system atrophy and TREM2 p.R47H

Ogaki, K., Heckman, M. G., Koga, S., Martens, Y. A., Labbé, C., Lorenzo-Betancor, O., Walton, R. L., Soto, A. I., Vargas, E. R., Fujioka, S., Uitti, R. J., Van Gerpen, J. A., Cheshire, W. P., Younkin, S. G., Wszolek, Z. K., Low, P. A., Singer, W., Bu, G., Dickson, D. W. & Ross, O. A., Aug 1 2018, In : Neurology: Genetics. 4, 4, e257.

Research output: Contribution to journalArticle

3 Scopus citations

Autonomic dysfunction and phenoconversion in idiopathic REM sleep behavior disorder

McCarter, S. J., Gehrking, T. L., St. Louis, E. K., Suarez, M. D., Boeve, B. F., Silber, M. H., Low, P. A. & Singer, W., Jun 1 2020, In : Clinical Autonomic Research. 30, 3, p. 207-213 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Autonomic function testing: Compliance and consequences

Rasmussen, T. K., Hansen, J., Low, P. A., Sandroni, P., Singer, W., Jensen, T. S. & Terkelsen, A. J., 2017, (Accepted/In press) In : Autonomic Neuroscience: Basic and Clinical.

Research output: Contribution to journalArticle

2 Scopus citations

Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests

Iodice, V., Lipp, A., Ahlskog, J. E., Sandroni, P., Fealey, R. D., Parisi, J. E., Matsumoto, J. Y., Benarroch, E. E., Kimpinski, K., Singer, W., Gehrking, T. L., Gehrking, J. A., Sletten, D. M., Schmeichel, A. M., Bower, J. H., Gilman, S., Figueroa, J. & Low, P. A., Apr 2012, In : Journal of Neurology, Neurosurgery and Psychiatry. 83, 4, p. 453-459 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

Central hyperadrenergic state after lightning strike

Parsaik, A. K., Ahlskog, J. E., Singer, W., Gelfman, R., Sheldon, S. H., Seime, R. J., Craft, J. M., Staab, J. P., Kantor, B. & Low, P. A., Aug 2013, In : Clinical Autonomic Research. 23, 4, p. 169-173 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical features and autonomic testing predict survival in multiple system atrophy

Coon, E. A., Sletten, D. M., Suarez, M. D., Mandrekar, J. N., Ahlskog, J. E., Bower, J. H., Matsumoto, J. Y., Silber, M. H., Benarroch, E. E., Fealey, R. D., Sandroni, P., Low, P. A. & Singer, W., Dec 1 2015, In : Brain. 138, 12, p. 3623-3631 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Cold face test demonstrates parasympathetic cardiac dysfunction in familial dysautonomia

Hilz, M. J., Stemper, B., Sauer, P., Haertl, U., Singer, W. & Axelrod, F. B., Jun 1 1999, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 276, 6 45-6, p. R1833-R1839

Research output: Contribution to journalArticle

53 Scopus citations

Comparison of baroreflex sensitivity with a fall and rise in blood pressure induced by the valsalva manoeuvre

Wada, N., Singer, W., Gehrking, T. L., Sletten, D. M., Schmelzer, J. D. & Low, P. A., 2014, In : Clinical Science. 127, 5, p. 307-313 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

COMPASS 31: A refined and abbreviated composite autonomic symptom score

Sletten, D. M., Suarez, G. A., Low, P. A., Mandrekar, J. & Singer, W., Dec 2012, In : Mayo Clinic proceedings. 87, 12, p. 1196-1201 6 p.

Research output: Contribution to journalArticle

127 Scopus citations

Conjugal multiple system atrophy: Chance, shared risk factors, or evidence of transmissibility?

Coon, E. A., Rocca, W., Melson, C. S., Ahlskog, J. E., Matsumoto, J. Y., Low, P. A. & Singer, W., Oct 2019, In : Parkinsonism and Related Disorders. 67, p. 10-13 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Deconditioning in patients with orthostatic intolerance

Parsaik, A., Allison, T. G., Singer, W., Sletten, D. M., Joyner, M. J., Benarroch, E. E., Low, P. A. & Sandroni, P., Oct 2 2012, In : Neurology. 79, 14, p. 1435-1439 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

Decreased orthostatic adrenergic reactivity in non-dipping postural tachycardia syndrome

Figueroa, J. J., Bott-Kitslaar, D. M., Mercado, J. A., Basford, J. R., Sandroni, P., Shen, W. K., Sletten, D. M., Gehrking, T. L., Gehrking, J. A., Low, P. A. & Singer, W., Oct 1 2014, In : Autonomic Neuroscience: Basic and Clinical. 185, p. 107-111 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Determination of vagal baroreflex sensitivity in normal subjects

Wada, N., Singer, W., Gehrking, T. L., Sletten, D. M., Schmelzer, J. D., Kihara, M. & Low, P. A., Oct 1 2014, In : Muscle and Nerve. 50, 4, p. 535-540 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

Shahnawaz, M., Mukherjee, A., Pritzkow, S., Mendez, N., Rabadia, P., Liu, X., Hu, B., Schmeichel, A., Singer, W., Wu, G., Tsai, A. L., Shirani, H., Nilsson, K. P. R., Low, P. A. & Soto, C., Feb 13 2020, In : Nature. 578, 7794, p. 273-277 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Disturbances of gastrointestinal transit and autonomic functions in postural orthostatic tachycardia syndrome

Loavenbruck, A., Iturrino, J., Singer, W., Sletten, D. M., Low, P. A., Zinsmeister, A. R. & Bharucha, A. E., Jan 1 2015, In : Neurogastroenterology and Motility. 27, 1, p. 92-98 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Do selective serotonin reuptake inhibitors improve survival in multiple system atrophy?

Coon, E. A., Ahlskog, J. E., Silber, M. H., Fealey, R. D., Benarroch, E. E., Sandroni, P., Mandrekar, J. N., Low, P. A. & Singer, W., Mar 2018, In : Parkinsonism and Related Disorders. 48, p. 51-53 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Earlier age of onset in multiple system atrophy with smoking and heavy alcohol use

Jackson, L., Coon, E. A., Ahlskog, J. E., Bower, J. H., Sandroni, P., Benarroch, E. E., Mandrekar, J. N., Low, P. A. & Singer, W., Sep 2019, In : Parkinsonism and Related Disorders. 66, p. 212-215 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effects of patient-controlled abdominal compression on standing systolic blood pressure in adults with orthostatic hypotension

Figueroa, J. J., Singer, W., Sandroni, P., Sletten, D. M., Gehrking, T. L., Gehrking, J. A., Low, P. & Basford, J. R., Mar 1 2015, In : Archives of Physical Medicine and Rehabilitation. 96, 3, p. 505-510 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Efficacy and safety of rifampicin for multiple system atrophy: A randomised, double-blind, placebo-controlled trial

Low, P. A., Robertson, D., Gilman, S., Kaufmann, H., Singer, W., Biaggioni, I., Freeman, R., Perlman, S., Hauser, R. A., Cheshire, W., Lessig, S., Vernino, S., Mandrekar, J., Dupont, W. D., Chelimsky, T. & Galpern, W. R., Mar 2014, In : The Lancet Neurology. 13, 3, p. 268-275 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Elimination of spurious absent sweat response in QSWEAT recordings

Corfits, J., Singer, W., Sandroni, P., Fealey, R. D., Coon, E. A., Benarroch, E. E., Berini, S. E., Mauermann, M. L., Sletten, D. M., Cutsforth-Gregory, J. K., Schmelzer, J. D. & Low, P. A., Dec 2019, In : Autonomic Neuroscience: Basic and Clinical. 222, 102589.

Research output: Contribution to journalArticle

Evidence of an intrinsic sinus node abnormality in patients with postural tachycardia syndrome

Singer, W., Shen, W. K., Opfer-Gehrking, T. L., McPhee, B. R., Hilz, M. J. & Low, P. A., Mar 2002, In : Mayo Clinic proceedings. 77, 3, p. 246-252 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Ganglionic Antibody Level as a Predictor of Severity of Autonomic Failure

Cutsforth-Gregory, J. K., McKeon, A., Coon, E. A., Sletten, D. M., Suarez, M., Sandroni, P., Singer, W., Benarroch, E. E., Fealey, R. D. & Low, P. A., Oct 2018, In : Mayo Clinic proceedings. 93, 10, p. 1440-1447 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Gastric emptying in postural tachycardia syndrome: A preliminary report

Park, K. J., Singer, W., Sletten, D. M., Low, P. A. & Bharucha, A. E., Aug 2013, In : Clinical Autonomic Research. 23, 4, p. 163-167 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Gi dysfunctions in diabetic gastroenteropathy, their relationships with symptoms, and effects of a GLP-1 antagonist

Chakraborty, S., Halland, M., Burton, D., Desai, A., Neja, B., Low, P., Singer, W., Camilleri, M., Zinsmeister, A. R. & Bharucha, A. E., Jun 1 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 1967-1977 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Heart rate-dependent electrocardiogram abnormalities in patients with postural tachycardia syndrome

Singer, W., Shen, W. K., Opfer-Gehrking, T. L., McPhee, B. R., Hilz, M. J. & Low, P. A., Jan 31 2003, In : Autonomic Neuroscience: Basic and Clinical. 103, 1-2, p. 106-113 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society

on behalf of the American Autonomic Society, Jan 2020, In : Autonomic Neuroscience: Basic and Clinical. 223, 102550.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society

on behalf of the American Autonomic Society, Feb 1 2020, In : Clinical Autonomic Research. 30, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Human papillomavirus vaccine (HPV) and autonomic disorders: A position statement from the American Autonomic Society

on behalf of the American Autonomic Society, Jan 1 2019, In : Autonomic Neuroscience: Basic and Clinical. 102550.

Research output: Contribution to journalArticle

Influence of posture on the Valsalva manoeuvre

Singer, W., Opfer-Gehrking, T. L., McPhee, B. R., Hilz, M. J. & Low, P. A., Apr 30 2001, In : Clinical Science. 100, 4, p. 433-440 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy

Singer, W., Dietz, A. B., Zeller, A. D., Gehrking, T. L., Schmelzer, J. D., Schmeichel, A. M., Gehrking, J. A., Suarez, M. D., Sletten, D. M., Minota Pacheco, K. V., Coon, E. A., Sandroni, P., Benarroch, E. E., Fealey, R. D., Matsumoto, J. Y., Bower, J. H., Hassan, A., Mckeon, A., Windebank, A. J., Mandrekar, J. N. & 1 others, Low, P. A., Jul 2 2019, In : Neurology. 93, 1, p. E77-E87

Research output: Contribution to journalArticle

10 Scopus citations

Invited Article: Autonomic ganglia: Target and novel therapeutic tool

Vernino, S., Sandroni, P., Singer, W. & Low, P. A., May 2008, In : Neurology. 70, 20, p. 1926-1932 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

Lower Vitamin B12 Level at Multiple System Atrophy Diagnosis Is Associated With Shorter Survival

McCarter, S. J., Coon, E. A., Savica, R., St Louis, E. K., Bower, J. H., Benarroch, E. E., Sandroni, P., Low, P. & Singer, W., Aug 1 2020, In : Movement Disorders. 35, 8, p. 1462-1466 5 p.

Research output: Contribution to journalArticle

MAPT haplotype diversity in multiple system atrophy

Labbé, C., Heckman, M. G., Lorenzo-Betancor, O., Murray, M. E., Ogaki, K., Soto-Ortolaza, A. I., Walton, R. L., Fujioka, S., Koga, S., Uitti, R. J., van Gerpen, J. A., Petersen, R. C., Graff-Radford, N. R., Younkin, S. G., Boeve, B. F., Cheshire, W. P., Low, P. A., Sandroni, P., Coon, E. A., Singer, W. & 3 others, Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Sep 1 2016, In : Parkinsonism and Related Disorders. 30, p. 40-45 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Multicenter trial of the proficiency of smart quantitative sensation tests

Dyck, P. J., Argyros, B., Russell, J. W., Gahnstrom, L. E., Nalepa, S., Albers, J. W., Lodermeier, K. A., Zafft, A. J., Dyck, P. J. B., Klein, C. J., Litchy, W. J., Davies, J. L., Carter, R. E., Melton, L. J., Low, P. A., Overland, C. J., Andersen, H., England, J. D., Llewelyn, G., Mauermann, M. L. & 5 others, Selvarajah, D., Singer, W., Smith, G., Tesfaye, S. & Vella, A., May 2014, In : Muscle and Nerve. 49, 5, p. 645-653 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Multiple system atrophy: Prognostic indicators of survival

Figueroa, J. J., Singer, W., Parsaik, A., Benarroch, E. E., Ahlskog, J. E., Fealey, R. D., Parisi, J. E., Sandroni, P., Mandrekar, J., Iodice, V., Low, P. A. & Bower, J. H., Aug 2014, In : Movement Disorders. 29, 9, p. 1151-1157 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Multiple system atrophy and apolipoprotein E

Ogaki, K., Martens, Y. A., Heckman, M. G., Koga, S., Labbé, C., Lorenzo-Betancor, O., Wernick, A. I., Walton, R. L., Soto, A. I., Vargas, E. R., Nielsen, H. M., Fujioka, S., Kanekiyo, T., Uitti, R. J., van Gerpen, J. A., Cheshire, W. P., Wszolek, Z. K., Low, P. A., Singer, W., Dickson, D. W. & 2 others, Bu, G. & Ross, O. A., Apr 2018, In : Movement Disorders. 33, 4, p. 647-650 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Natural history of multiple system atrophy in the USA: A prospective cohort study

Low, P. A., Reich, S. G., Jankovic, J., Shults, C. W., Stern, M. B., Novak, P., Tanner, C. M., Gilman, S., Marshall, F. J., Wooten, F., Racette, B., Chelimsky, T., Singer, W., Sletten, D. M., Sandroni, P. & Mandrekar, J., Jul 1 2015, In : The Lancet Neurology. 14, 7, p. 710-719 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Natural history of pure autonomic failure: A United States prospective cohort

on behalf of the Autonomic Disorders Consortium, Feb 1 2017, In : Annals of neurology. 81, 2, p. 287-297 11 p.

Research output: Contribution to journalArticle

103 Scopus citations

Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies

Autonomic Disorders Consortium, Mar 2018, In : Annals of neurology. 83, 3, p. 522-531 10 p.

Research output: Contribution to journalArticle

38 Scopus citations