• 6558 Citations
  • 38 Scopus h-Index
19972021

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Article
2013

Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

Grzenda, A., Lomberk, G., Svingen, P., Mathison, A., Calvo, E., Iovanna, J., Xiong, Y., Faubion, W. & Urrutia, R., Mar 4 2013, In : Epigenetics and Chromatin. 6, 1, 3.

Research output: Contribution to journalArticle

20 Scopus citations

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele

Kauder, S. E., Santell, L., Mai, E., Wright, L. Y., Luis, E., N'Diaye, E. N., Lutman, J., Ratti, N., Sa, S. M., Maun, H. R., Stefanich, E., Gonzalez, L. C., Graham, R. R., Diehl, L., Faubion, W. A., Keir, M. E., Young, J., Chaudhuri, A., Lazarus, R. A. & Egen, J. G., Dec 23 2013, In : PloS one. 8, 12, e83958.

Research output: Contribution to journalArticle

10 Scopus citations

Incidence, clinical characteristics, and natural history of pediatric IBD in Wisconsin: A population-based epidemiological study

Adamiak, T., Walkiewicz-Jedrzejczak, D., Fish, D., Brown, C., Tung, J., Khan, K., Faubion, W., Park, R., Heikenen, J., Yaffee, M., Rivera-Bennett, M. T., Wiedkamp, M., Stephens, M., Noel, R., Nugent, M., Nebel, J., Simpson, P., Kappelman, M. D. & Kugathasan, S., May 1 2013, In : Inflammatory bowel diseases. 19, 6, p. 1218-1223 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis

Zeisler, B., Lerer, T., Markowitz, J., MacK, D., Griffiths, A., Bousvaros, A., Keljo, D., Rosh, J., Evans, J., Kappelman, M., Otley, A., Kay, M., Grossman, A., Saeed, S., Carvalho, R., Oliva-Hemker, M., Faubion, W., Sudel, B., Pfefferkorn, M., Ashai-Khan, F. & 2 others, Leleiko, N. & Hyams, J., Jan 1 2013, In : Journal of pediatric gastroenterology and nutrition. 56, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Outcomes of patients with microscopic colitis treated with corticosteroids: A population-based study

Gentile, N. M., Abdalla, A. A., Khanna, S., Smyrk, T. C., Tremaine, W. J., Faubion, W. A., Kammer, P. P., Sandborn, W. J., Loftus, E. V. & Pardi, D. S., Feb 1 2013, In : American Journal of Gastroenterology. 108, 2, p. 256-259 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Regulatory T cell kinetics in the peripheral blood of patients with Crohn's disease

Rahman, M. K., Offord, C. P., Khanna, S., Ford, G. C., Perrson, X. M. T., Svingen, P. A., Xiong, Y., Bajzer, Z. & Faubion, W. A., Feb 1 2013, In : Human Immunology. 74, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Risk factors for lymphoma in patients with inflammatory bowel disease: A case-control study

Afif, W., Sandborn, W. J., Faubion, W. A., Rahman, M., Harmsen, S. W., Zinsmeister, A. R. & Loftus, E. V., Jun 1 2013, In : Inflammatory bowel diseases. 19, 7, p. 1384-1389 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

Mathison, A., Grzenda, A., Lomberk, G., Velez, G., Buttar, N., Tietz, P., Hendrickson, H., Liebl, A., Xiong, Y. Y., Gores, G., Fernandez-Zapico, M., LaRusso, N. F., Faubion, W., Shah, V. H. & Urrutia, R., Sep 16 2013, In : PloS one. 8, 9, e75311.

Research output: Contribution to journalArticle

18 Scopus citations

The epidemiology of clostridium difficile infection in children: A population-based study

Khanna, S., Baddour, L. M., Huskins, W. C., Kammer, P. P., Faubion, W. A., Zinsmeister, A. R., Harmsen, W. S. & Pardi, D. S., May 15 2013, In : Clinical Infectious Diseases. 56, 10, p. 1401-1406 6 p.

Research output: Contribution to journalArticle

128 Scopus citations

Validation of the Ulcerative Colitis Colonoscopic Index of Severity and Its Correlation With Disease Activity Measures

Samuel, S., Bruining, D. H., Loftus, E. V., Thia, K. T., Schroeder, K. W., Tremaine, W. J., Faubion, W. A., Kane, S. V., Pardi, D. S., de Groen, P. C., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Jan 2013, In : Clinical Gastroenterology and Hepatology. 11, 1, p. 49-54.e1

Research output: Contribution to journalArticle

66 Scopus citations
2012

Benefit of computed tomography enterography in Crohn's disease: Effects on patient management and physician level of confidence

Bruining, D. H., Siddiki, H. A., Fletcher, J. G., Sandborn, W. J., Fidler, J. L., Huprich, J. E., Mandrekar, J. N., Harmsen, W. S., Evans, P. E., Faubion, W. A., Hanson, K. A., Ingle, S. B., Pardi, D. S., Schroeder, K. W., Tremaine, W. J. & Loftus, E. V., Feb 1 2012, In : Inflammatory bowel diseases. 18, 2, p. 219-225 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Biomarkers of therapeutic response in the IL-23 pathway in inflammatory bowel disease

Cayatte, C., Joyce-Shaikh, B., Vega, F., Boniface, K., Grein, J., Murphy, E., Blumenschein, W. M., Chen, S., Malinao, M. C., Basham, B., Pierce, R. H., Bowman, E. P., McKenzie, B. S., Elson, C. O., Faubion, W. A., Malefyt, R. D. W., Kastelein, R. A., Cua, D., McClanahan, T. K. & Beaumont, M., Jun 11 2012, In : Clinical and translational gastroenterology. 3, e10.

Research output: Contribution to journalArticle

38 Scopus citations

Health supervision in the management of children and adolescents with IBD: NASPGHAN recommendations

Rufo, P. A., Denson, L. A., Sylvester, F. A., Szigethy, E., Sathya, P., Lu, Y., Wahbeh, G. T., Sena, L. M. & Faubion, W. A., Jul 1 2012, In : Journal of pediatric gastroenterology and nutrition. 55, 1, p. 93-108 16 p.

Research output: Contribution to journalArticle

56 Scopus citations

MR enterography in pediatric inflammatory bowel disease: Retrospective assessment of patient tolerance, image quality, and initial performance estimates

Absah, I., Bruining, D. H., Matsumoto, J. M., Weisbrod, A. J., Fletcher, J. G., Fidler, J. L. & Faubion, W. A., Sep 1 2012, In : American Journal of Roentgenology. 199, 3, p. W367-W375

Research output: Contribution to journalArticle

38 Scopus citations

Natalizumab for moderate to severe Crohn's disease in clinical practice: The Mayo Clinic Rochester experience

Kane, S. V., Horst, S., Sandborn, W. J., Becker, B., Neis, B., Moscandrew, M., Hanson, K. A., Tremaine, W. J., Bruining, D. H., Faubion, W. A., Pardi, D. S., Harmsen, W. S., Zinsmeister, A. R. & Loftus, E. V., Dec 1 2012, In : Inflammatory bowel diseases. 18, 12, p. 2203-2208 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Pediatric chronic ulcerative colitis: Does infliximab increase post-ileal pouch anal anastomosis complications?

Kennedy, R., Potter, D. D., Moir, C., Zarroug, A. E., Faubion, W. & Tung, J., Jan 1 2012, In : Journal of pediatric surgery. 47, 1, p. 199-203 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner

Xiong, Y., Khannas, S., Grzenda, A. L., Sarmento, O. F., Svingen, P. A., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Oct 5 2012, In : Journal of Biological Chemistry. 287, 41, p. 34372-34385 14 p.

Research output: Contribution to journalArticle

36 Scopus citations

Safety and efficacy of adalimumab for moderate to severe crohn's disease in children

Hyams, J. S., Griffiths, A., Markowitz, J., Baldassano, R. N., Faubion, W. A., Colletti, R. B., Dubinsky, M., Kierkus, J., Rosh, J., Wang, Y., Huang, B., Bittle, B., Marshall, M. & Lazar, A., Aug 2012, In : Gastroenterology. 143, 2, p. 365-374.e2

Research output: Contribution to journalArticle

139 Scopus citations

Signaling lymphocyte activation molecule regulates development of colitis in mice

Van Driel, B., Liao, G., Romero, X., O'Keeffe, M. S., Wang, G., Faubion, W. A., Berger, S. B., Magelky, E. M., Manocha, M., Azcutia, V., Grisham, M., Luscinskas, F. W., Mizoguchi, E., De Waal Malefyt, R., Reinecker, H. C., Bhan, A. K., Wang, N. & Terhorst, C., Dec 2012, In : Gastroenterology. 143, 6, p. 1544-1554.e7

Research output: Contribution to journalArticle

11 Scopus citations
2011

Measurement of disease activity in ulcerative colitis: Interobserver agreement and predictors of severity

Thia, K. T., Loftus, E. V., Pardi, D. S., Kane, S. V., Faubion, W. A., Tremaine, W. J., Schroeder, K. W., Harmsen, S. W., Zinsmeister, A. R. & Sandborn, W. J., Jun 1 2011, In : Inflammatory bowel diseases. 17, 6, p. 1257-1264 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Short CDAI: Development and validation of a shortened and simplified Crohn's disease activity index

Thia, K., Faubion, W. A., Loftus, E. V., Persson, T., Persson, A. & Sandborn, W. J., Jan 2011, In : Inflammatory bowel diseases. 17, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Single molecule measurements of tumor necrosis factor α and interleukin-6 in the plasma of patients with Crohn's disease

Song, L., Hanlon, D. W., Chang, L., Provuncher, G. K., Kan, C. W., Campbell, T. G., Fournier, D. R., Ferrell, E. P., Rivnak, A. J., Pink, B. A., Minnehan, K. A., Patel, P. P., Wilson, D. H., Till, M. A., Faubion, W. A. & Duffy, D. C., Sep 30 2011, In : Journal of Immunological Methods. 372, 1-2, p. 177-186 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2010

Adalimumab for Crohns disease in clinical practice at Mayo clinic: The first 118 patients

Swoger, J. M., Loftus, E. V., Tremaine, W. J., Faubion, W. A., Pardi, D. S., Kane, S. V., Hanson, K. A., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Nov 1 2010, In : Inflammatory bowel diseases. 16, 11, p. 1912-1921 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease

Afif, W., Loftus, E. V., Faubion, W. A., Kane, S. V., Bruining, D. H., Hanson, K. A. & Sandborn, W. J., May 1 2010, In : American Journal of Gastroenterology. 105, 5, p. 1133-1139 7 p.

Research output: Contribution to journalArticle

381 Scopus citations

Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver

Jagavelu, K., Routray, C., Shergill, U., O'Hara, S. P., Faubion, W. & Shah, V. H., Aug 1 2010, In : Hepatology. 52, 2, p. 590-601 12 p.

Research output: Contribution to journalArticle

82 Scopus citations

Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion

Cao, T., Wenzel, S. E., Faubion, W. A., Harriman, G. & Li, L., Sep 1 2010, In : Clinical Immunology. 136, 3, p. 329-337 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Recurrence and impact of postoperative prophylaxis in laparoscopically treated primary ileocolic crohn disease

Malireddy, K., Larson, D. W., Sandborn, W. J., Loftus, E. V., Faubion, W. A., Pardi, D. S., Qin, R., Gullerud, R. E., Cima, R. R., Wolff, B. & Dozois, E. J., Jan 1 2010, In : Archives of Surgery. 145, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

Berger, S. B., Romero, X., Ma, C., Wang, G., Faubion, W. A., Liao, G., Compeer, E., Keszei, M., Rameh, L., Wang, N., Boes, M., Regueiro, J. R., Reinecker, H. C. & Terhorst, C., Oct 1 2010, In : Nature immunology. 11, 10, p. 920-927 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival

Rahman, M. K., Midtling, E. H., Svingen, P. A., Xiong, Y., Bell, M. P., Tung, J., Smyrk, T., Egan, L. J. & Faubion, W. A., Jun 15 2010, In : Journal of Immunology. 184, 12, p. 7247-7256 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
2009

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

Kleinschek, M. A., Boniface, K., Sadekova, S., Grein, J., Murphy, E. E., Turner, S. P., Raskin, L., Desai, B., Faubion, W. A., De Malefyt, R. W., Pierce, R. H., McClanahan, T. & Kastelein, R. A., Mar 16 2009, In : Journal of Experimental Medicine. 206, 3, p. 525-534 10 p.

Research output: Contribution to journalArticle

319 Scopus citations

Open-label study of adalimumab in patients with ulcerative colitis including those with prior loss of response or intolerance to infliximab

Afif, W., Leighton, J. A., Hanauer, S. B., Loftus, E. V., Faubion, W. A., Pardi, D. S., Tremaine, W. J., Kane, S. V., Bruining, D. H., Cohen, R. D., Rubin, D. T., Hanson, K. A. & Sandborn, W. J., Nov 26 2009, In : Inflammatory bowel diseases. 15, 9, p. 1302-1307 6 p.

Research output: Contribution to journalArticle

116 Scopus citations
2008

IX. Report of pediatric workgroup

Sylvester, F. A., Bousvaros, A., Dubinsky, M., Faubion, W., Guthery, S., Hyams, J., Kugathasan, S., Polk, D. B. & Szigethy, E., May 1 2008, In : Inflammatory bowel diseases. 14, 5, p. 705-706 2 p.

Research output: Contribution to journalArticle

Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial

Solem, C. A., Loftus, E. V., Fletcher, J. G., Baron, T. H., Gostout, C. J., Petersen, B. T., Tremaine, W. J., Egan, L. J., Faubion, W. A., Schroeder, K. W., Pardi, D. S., Hanson, K. A., Jewell, D. A., Barlow, J. M., Fidler, J. L., Huprich, J. E., Johnson, C. D., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Aug 1 2008, In : Gastrointestinal endoscopy. 68, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

269 Scopus citations

X. Challenges update workgroups

Stenson, W. F., Snapper, S. B., Duerr, R. H., Cho, J. H., Kugathasan, S., Rioux, J. D., Sartor, R. B., Autenreith, I. B., Darfeuille-Michaud, A., Fox, J., Tannock, G. W., Versalovic, J., Young, V. B., Elson, C. O., Mayer, L. F., Weaver, C. T., Lencer, W. I., Colgan, S. P., Parkos, C. A., Silverberg, M. S. & 24 others, Targan, S. R., Rubin, D. T., Loftus, E. V., Vasiliauskas, E. A., Sands, B. E., Higgins, P., D'Haens, G., Feagan, B. G., Hanauer, S. B., Sandborn, W. J., Steinhart, H., Fazio, V., Galandiuk, S., Koltun, W. A., Strong, S. A., Sylvester, F. A., Bousvaros, A., Dubinsky, M., Faubion, W. A., Griffiths, A. M., Guthery, S. L., Hyams, J. S., Polk, D. B. & Szigethy, E., May 1 2008, In : Inflammatory bowel diseases. 14, 5, p. 706-708 3 p.

Research output: Contribution to journalArticle

2007

FOXP3 regulates TLR10 expression in human T regulatory cells

Bell, M. P., Svingen, P. A., Rahman, M. K., Xiong, Y. & Faubion, W. A., Aug 1 2007, In : Journal of Immunology. 179, 3, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: Dependence on TCR:Peptide-MHC interaction, ICAM-1, IL-12, and IFN-γ

Radhakrishnan, S., Wiehagen, K. R., Pulko, V., Van Keulen, V. P., Faubion, W. A., Knutson, K. L. & Pease, L. R., Mar 15 2007, In : Journal of Immunology. 178, 6, p. 3583-3592 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2006

A population-based study of the frequency of corticosteroid resistance and dependence in pediatric patients with Crohn's disease and ulcerative colitis

Tung, J., Loftus, E. V., Freese, D. K., El-Youssef, M., Zinsmeister, A. R., Melton, L. J., Harmsen, W. S., Sandborn, W. J. & Faubion, W. A., Dec 1 2006, In : Inflammatory bowel diseases. 12, 12, p. 1093-1100 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Budesonide in the treatment of inflammatory bowel disease: The first year of experience in clinical practice

Chopra, A., Pardi, D. S., Loftus, E. V., Tremaine, W. J., Egan, L. J., Faubion, W. A., Hanson, K. A., Johnson, T. A. & Sandborn, W. J., Jan 1 2006, In : Inflammatory bowel diseases. 12, 1, p. 29-32 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

CD48 Controls T-Cell and Antigen-Presenting Cell Functions in Experimental Colitis

Abadía-Molina, A. C., Ji, H., Faubion, W. A., Julien, A., Latchman, Y., Yagita, H., Sharpe, A., Bhan, A. K. & Terhorst, C., Feb 2006, In : Gastroenterology. 130, 2, p. 424-434 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice

Graham, D. B., Bell, M. P., McCausland, M. M., Huntoon, C. J., Van Deursen, J., Faubion, W. A., Crotty, S. & McKean, D. J., Jan 1 2006, In : Journal of Immunology. 176, 1, p. 291-300 10 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations
2005

Cutting edge: The SLAM family receptor Ly108 controls T cell and neutrophil functions

Howie, D., Laroux, F. S., Morra, M., Satoskar, A. R., Rosas, L. E., Faubion, W. A., Julien, A., Rietdijk, S., Coyle, A. J., Fraser, C. & Terhorst, C., May 15 2005, In : Journal of Immunology. 174, 10, p. 5931-5935 5 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations

Endoscopic factors in the diagnosis of colorectal dysplasia in chronic inflammatory bowel disease

Toruner, M., Harewood, G. C., Loftus, E. V., Sandborn, W. J., Tremaine, W. J., Faubion, W. A., Schroeder, K. W. & Egan, L. J., May 1 2005, In : Inflammatory bowel diseases. 11, 5, p. 428-434 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

In vivo generation of oligoclonal colitic CD4+ T-cell lines expressing a distinct T-cell receptor Vβ

Abadía-Molina, A. C., Mizoguchi, A., Faubion, W. A., De Jong, Y. P., Rietdijk, S. T., Comiskey, M., Clarke, K., Bhan, A. K. & Terhorst, C., May 2005, In : Gastroenterology. 128, 5, p. 1268-1277 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Workshop report: Prevention of postoperative recurrence in Crohn's disease

Markowitz, J., Markowitz, J. E., Bousvaros, A., Crandall, W., Faubion, W., Kirschner, B. S., Perrault, J., Rosh, J. & Winter, H., Aug 1 2005, In : Journal of pediatric gastroenterology and nutrition. 41, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2004

Colitis is associated with thymic destruction attenuating CD4 +25+ regulatory T cells in the periphery

Faubion, W. A., De Jong, Y. P., Molina, A. A., Hongbin, J. I., Clarke, K., Wang, B., Mizoguchi, E., Simpson, S. J., Bhan, A. K. & Terhorst, C., Jun 2004, In : Gastroenterology. 126, 7, p. 1759-1770 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Cutting Edge: The Natural Ligand for Glucocorticoid-Induced TNF Receptor-Related Protein Abrogates Regulatory T Cell Suppression

Ji, H. B., Liao, G., Faubion, W. A., Abadía-Molina, A. C., Cozzo, C., Laroux, F. S., Caton, A. & Terhorst, C., May 15 2004, In : Journal of Immunology. 172, 10, p. 5823-5827 5 p.

Research output: Contribution to journalArticle

Open Access
169 Scopus citations

The Cell Surface Receptor SLAM Controls T Cell and Macrophage Functions

Wang, N., Satoskar, A., Faubion, W., Howie, D., Okamoto, S., Feske, S., Gullo, C., Clarke, K., Sosa, M. R., Sharpe, A. H. & Terhorst, C., May 3 2004, In : Journal of Experimental Medicine. 199, 9, p. 1255-1264 10 p.

Research output: Contribution to journalArticle

139 Scopus citations
2001

Development of chronic colitis is dependent on the cytokine MIF

De Jong, Y. P., Abadia-Molina, A. C., Satoskar, A. R., Clarke, K., Rietdijk, S. T., Faubion, W. A., Mizoguchi, E., Metz, C. N., Sahli, M. A., Ten Hove, T., Keates, A. C., Lubetsky, J. B., Farrell, R. J., Michetti, P., Van Deventer, S. J., Lolis, E., David, J. R., Bhan, A. K. & Terhorst, C., Nov 28 2001, In : Nature immunology. 2, 11, p. 1061-1066 6 p.

Research output: Contribution to journalArticle

261 Scopus citations

Pediatric "PSC-IBD": A descriptive report of associated inflammatory bowel disease among pediatric patients with PSC

Faubion, W. A., Loftus, E. V., Sandborn, W. J., Freese, D. K. & Perrault, J., Oct 20 2001, In : Journal of pediatric gastroenterology and nutrition. 33, 3, p. 296-300 5 p.

Research output: Contribution to journalArticle

85 Scopus citations

The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study

Faubion, W. A., Loftus, E. V., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Jan 1 2001, In : Gastroenterology. 121, 2, p. 255-260 6 p.

Research output: Contribution to journalArticle

927 Scopus citations