William Alvis Faubion, MD

Research Output

Research Output per year

1997 2021

• 7013 Citations
• 42 Scopus h-Index
• 113 Article
• 21 Review article
• 4 Comment/debate
• 3 Chapter
• 5 More
  • 2 Letter
  • 2 Short survey
  • 1 Editorial

Research Output per year

Research Output per year

Search results

• 2020

  Deregulation of long intergenic non-coding RNAs in CD4⁺ T cells of lamina propria in Crohn's disease through transcriptome profiling

  Braga-Neto, M. B., Gaballa, J. M., Bamidele, A. O., Sarmento, O. F., Svingen, P., Gonzalez, M., Ramos, G. P., Sagstetter, M. R., Aseem, S. O., Sun, Z. & Faubion, W. A., Jan 1 2020, In: Journal of Crohn's and Colitis. 14, 1, p. 96-109 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Long Noncoding RNA
  • Gene Expression Profiling
  • Crohn Disease
  • Mucous Membrane
  • T-Lymphocytes
  4 Scopus citations

• Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary

  Turner, D., Griffiths, A. M., Wilson, D., Mould, D. R., Baldassano, R. N., Russell, R. K., Dubinsky, M., Heyman, M. B., De Ridder, L., Hyams, J., Martin De Carpi, J., Conklin, L., Faubion, W. A., Koletzko, S., Bousvaros, A. & Ruemmele, F. M., Jan 1 2020, In: Gut. 69, 1, p. 32-41 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Inflammatory Bowel Diseases
  • Clinical Trials
  • Pediatrics
  • Drug Approval
  • Child
  6 Scopus citations

• Long-term SARS-CoV-2 RNA shedding and its temporal association to IgG seropositivity

  Agarwal, V., Venkatakrishnan, A. J., Puranik, A., Kirkup, C., Lopez-Marquez, A., Challener, D. W., Theel, E. S., O’Horo, J. C., Binnicker, M. J., Kremers, W. K., Faubion, W. A., Badley, A. D., Williams, A. W., Gores, G. J., Halamka, J. D., Morice, W. G. & Soundararajan, V., Dec 2020, In: Cell Death Discovery. 6, 1, 138.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus
  • Immunoglobulin G
  • RNA
  • Viral RNA
  • Virus Shedding
  1 Scopus citations

• Long-term SARS-CoV-2 RNA shedding and its temporal association to IgG seropositivity

  Agarwal, V., Venkatakrishnan, A. J., Puranik, A., Kirkup, C., Lopez-Marquez, A., Challener, D. W., O’Horo, J. C., Binnicker, M. J., Kremers, W. K., Faubion, W. A., Badley, A. D., Williams, A. W., Gores, G. J., Halamka, J. D., Morice, W. G. & Soundararajan, V., Jul 7 2020, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • SARS Virus
  • Immunoglobulin G
  • RNA
  • Viral RNA
  • Virus Shedding

• Plasma IL-6 levels following corticosteroid therapy as an indicator of ICU length of stay in critically ill COVID-19 patients

  Awasthi, S., Wagner, T., Venkatakrishnan, A. J., Puranik, A., Hurchik, M., Agarwal, V., Conrad, I., Kirkup, C., Arunachalam, R., O'Horo, J., Kremers, W., Kashyap, R., Morice, W., Halamka, J., Williams, A. W., Faubion, W. A., Badley, A. D., Gores, G. J. & Soundararajan, V., Jul 3 2020, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • Critical Illness
  • Intensive Care Units
  • Adrenal Cortex Hormones
  • Interleukin-6
  • Length of Stay

• Unique Phenotypic Characteristics and Clinical Course in Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience

  Wang, M. H., Mousa, O. Y., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Apr 11 2020, In: Inflammatory bowel diseases. 26, 5, p. 774-779 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Sclerosing Cholangitis
  • Ulcerative Colitis
  • Odds Ratio
  • Logistic Models
  • Phenotype
• 2019

  A Comprehensive Approach to Pouch Disorders

  Quinn, K. P., Lightner, A., Faubion, W. A. & Raffals, L. E. H., Feb 21 2019, In: Inflammatory bowel diseases. 25, 3, p. 460-471 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Restorative Proctocolectomy
  • Ulcerative Colitis
  • Pouchitis
  • Adenomatous Polyposis Coli
  • Colitis
  6 Scopus citations

• An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study

  Muñiz Pedrogo, D. A., Chen, J., Hillmann, B., Jeraldo, P., Al-Ghalith, G., Taneja, V., Davis, J. M., Knights, D., Nelson, H., Faubion, W. A., Raffals, L. & Kashyap, P. C., Apr 11 2019, In: Inflammatory bowel diseases. 25, 5, p. 902-913 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Clostridiaceae
  • Inflammatory Bowel Diseases
  • Arthritis
  • Rheumatoid Arthritis
  • Cross-Sectional Studies
  12 Scopus citations

• Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn's patients

  Lightner, A., McKenna, N. P., Alsughayer, A., Loftus, Jr, E. V., Raffals, L. E. H., Faubion, W. A. & Moir, C., Jan 1 2019, In: Journal of pediatric surgery.

  Research output: Contribution to journal › Article › peer-review

  • Biological Therapy
  • Pediatric Crohn's disease
  • Pediatrics
  • Morbidity
  • Postoperative Complications
  3 Scopus citations

• Disruption of FOXP3–EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation

  Bamidele, A. O., Svingen, P. A., Sagstetter, M. R., Sarmento, O. F., Gonzalez, M., Braga Neto, M. B., Kugathasan, S., Lomberk, G., Urrutia, R. A. & Faubion, W. A., 2019, In: CMGH. 7, 1, p. 55-71 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Forkhead Transcription Factors
  • Enhancer of Zeste Homolog 2 Protein
  • Crohn Disease
  • Inflammation
  • Interleukin-6
  6 Scopus citations

• Early Results of a Phase I Trial Using an Adipose-Derived Mesenchymal Stem Cell-Coated Fistula Plug for the Treatment of Transsphincteric Cryptoglandular Fistulas

  Dozois, E., Lightner, A., Mathis, K. L., Chua, H. K., Kelley, S. R., Fletcher, J. G., Dietz, A. B., Friton, J. J., Butler, G. W. & Faubion, W. A., May 1 2019, In: Diseases of the colon and rectum. 62, 5, p. 615-622 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesenchymal Stem Cells
  • Fistula
  • Therapeutics
  • Seroma
  • Clinical Trials, Phase I
  9 Scopus citations

• Loss of rnf40 decreases nf-κb activity in colorectal cancer cells and reduces colitis burden in mice

  Kosinsky, R. L., Chua, R. L., Qui, M., Saul, D., Mehlich, D., Ströbel, P., Schildhaus, H. U., Wegwitz, F., Faubion, W. A. & Johnsen, S. A., Mar 26 2019, In: Journal of Crohn's and Colitis. 13, 3, p. 362-373 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Colitis
  • Colorectal Neoplasms
  • Inflammation
  • In Vitro Techniques
  • Colon
  14 Scopus citations

• MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis

  Abe, J. I., Ko, K. A., Kotla, S., Wang, Y., Paez-Mayorga, J., Shin, I. J., Imanishi, M., Vu, H. T., Tao, Y., Leiva-Juarez, M. M., Thomas, T. N., Medina, J. L., Won, J. H., Fujii, Y., Giancursio, C. J., McBeath, E., Shin, J. H., Guzman, L., Abe, R. J., Taunton, J. & 6 others, Mochizuki, N., Faubion, W., Cooke, J. P., Fujiwara, K., Evans, S. E. & Le, N. T., Apr 4 2019, In: JCI Insight. 4, 7, e125570.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endoplasmic Reticulum Stress
  • Atherosclerosis
  • Endothelial Cells
  • 90-kDa Ribosomal Protein S6 Kinases
  • Activating Transcription Factor 6
  6 Scopus citations

• Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

  Wang, M. H., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In: Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

  Research output: Contribution to journal › Article › peer-review

  • Inflammatory Bowel Diseases
  • Tumor Necrosis Factor-alpha
  • Genetic Loci
  • Sex Factors
  • Odds Ratio
  2 Scopus citations

• Update on the Natural Course of Fistulizing Perianal Crohn's Disease in a Population-Based Cohort

  Park, S. H., Aniwan, S., Scott Harmsen, W., Tremaine, W. J., Lightner, A. L., Faubion, W. A. & Loftus, E. V., 2019, In: Inflammatory bowel diseases. 25, 6, p. 1054-1060 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rectovaginal Fistula
  • Crohn Disease
  • Proctectomy
  • Population
  • Incidence
  13 Scopus citations
• 2018

  AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

  Ichikawa, R., Lamb, C. A., Eastham-Anderson, J., Scherl, A., Raffals, L., Faubion, W. A., Bennett, M. R., Long, A. K., Mansfield, J. C., Kirby, J. A. & Keir, M. E., Nov 9 2018, In: Journal of Crohn's & colitis. 12, 10, p. 1191-1199 9 p.

  Research output: Contribution to journal › Article › peer-review

  • alpha E integrins
  • Ileum
  • rhuMAb Beta7
  • Colon
  • Inflammation
  8 Scopus citations

• Clinical benefit of capsule endoscopy in Crohn's disease: Impact on patient management and prevalence of proximal small bowel involvement

  Hansel, S. L., McCurdy, J. D., Barlow, J. M., Fidler, J., Fletcher, J. G., Becker, B., Prabhu, N. C., Faubion, W. A., Hanson, K. A., Kane, S. V., Kisiel, J. B., Loftus, E. V., Papadakis, K. A., Pardi, D. S., Raffals, L. E., Schoenoff, S., Tremaine, W. J. & Bruining, D. H., Jun 8 2018, In: Inflammatory bowel diseases. 24, 7, p. 1582-1588 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Capsule Endoscopy
  • Crohn Disease
  • Magnetic Resonance Spectroscopy
  • Pathologic Constriction
  • Tomography
  12 Scopus citations

• Efficacy of adalimumab for treatment of perianal fistula in children with moderately to severely active Crohn's disease: Results from imagine 1 and imagine 2

  Ruemmele, F. M., Rosh, J., Faubion, W. A., Dubinsky, M. C., Turner, D., Lazar, A., Eichner, S., Maa, J. F., Alperovich, G., Robinson, A. M. & Hyams, J. S., 2018, In: Journal of Crohn's and Colitis. 12, 10, p. 1249-1254 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Adalimumab
  • Crohn Disease
  • Fistula
  • Child
  • Safety
  10 Scopus citations

• Epigenetics of gastrointestinal diseases: notes from a workshop

  Marks, D. L., Olson, R. L., Urrutia, R., Billadeau, D. D., Roy, N., Calin, G. A., Fabbri, M., Koutsioumpa, M., Iliopoulos, D., Ordog, T., Huebert, R., Sarmento, O., Bamidele, A. O., Faubion, W., Lomberk, G. L., Siveke, J., Ahuja, N., Iovanna, J., Hlady, R. A., Robertson, K. & 3 others, Kisiel, J., Pin, C. L. & Fernandez-Zapico, M. E., Apr 3 2018, In: Epigenetics. 13, 4, p. 449-457 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal Diseases
  • Epigenomics
  • Education
  • DNA Methylation
  • Biomarkers

• In-patient outcomes of Hematopoietic Stem Cell Transplantation in Patients with Immune Mediated Inflammatory Diseases: A Nationwide Study

  Mehta, K., Jaiswal, P., Briggs, F., Faubion, W. A., Tabibian, J. H., Cominelli, F. & Dave, M., Dec 1 2018, In: Scientific Reports. 8, 1, 6825.

  Research output: Contribution to journal › Article › peer-review

  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells
  • Transplants
  • Cell Transplantation
  • Ulcerative Colitis
  2 Scopus citations

• Outcomes of endoscopic therapy for luminal strictures in Crohn's disease

  Shivashankar, R., Varayil, J. E., Harmsen, W. S., Faubion, W. A., Song, L. M. W. K., Bruining, D. H., Schroeder, K. W., Kisiel, J., Loftus, E. V. & Prabhu, N. C., Jun 8 2018, In: Inflammatory bowel diseases. 24, 7, p. 1575-1581 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Crohn Disease
  • Dilatation
  • Pathologic Constriction
  • Therapeutics
  • Endoscopes
  8 Scopus citations
• 2017

  Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results from the MAL-ED Study

  Kosek, M. N., Lee, G. O., Guerrant, R. L., Haque, R., Kang, G., Ahmed, T., Bessong, P., Ali, A., Mduma, E., Peñataro Yori, P., Faubion, W. A., Lima, A. A. M., Paredes Olortegui, M., Mason, C., Babji, S., Singh, R., Qureshi, S., Kosek, P. S., Samie, A., Pascal, J. & 7 others, Shrestha, S., McCormick, B. J. J., Seidman, J. C., Lang, D. R., Zaidi, A., Caulfield, L. E. & Gottlieb, M., Jul 1 2017, In: Journal of pediatric gastroenterology and nutrition. 65, 1, p. 31-39 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lactulose
  • Mannitol
  • Permeability
  • Sex Characteristics
  • Brazil
  23 Scopus citations

• Autologous Mesenchymal Stem Cells, Applied in a Bioabsorbable Matrix, for Treatment of Perianal Fistulas in Patients With Crohn's Disease

  Dietz, A. B., Dozois, E. J., Fletcher, J. G., Butler, G. W., Radel, D., Lightner, A. L., Dave, M., Friton, J., Nair, A., Camilleri, E. T., Dudakovic, A., van Wijnen, A. J. & Faubion, W. A., Jul 2017, In: Gastroenterology. 153, 1, p. 59-62.e2

  Research output: Contribution to journal › Article › peer-review

  • Crohn Disease
  • Mesenchymal Stem Cells
  • Fistula
  • Therapeutics
  • Morbidity
  67 Scopus citations

• Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study

  Westera, L., Van Viegen, T., Jeyarajah, J., Azad, A., Bilsborough, J., Van Den Brink, G. R., Cremer, J., Danese, S., D'Haens, G., Eckmann, L., Faubion, W., Filice, M., Korf, H., McGovern, D., Panes, J., Salas, A., Sandborn, W. J., Silverberg, M. S., Smith, M. I., Vermeire, S. & 8 others, Vetrano, S., Shackelton, L. M., Stitt, L., Jairath, V., Levesque, B. G., Spencer, D. M., Feagan, B. G. & Casteele, N. V., Nov 2 2017, In: Clinical and translational gastroenterology. 8, 11, e126.

  Research output: Contribution to journal › Article › peer-review

  • Multicenter Studies
  • Flow Cytometry
  • Prospective Studies
  • Ionomycin
  • phorbol-12-myristate
  7 Scopus citations

• Colectomy in refractory Crohn's colitis improves nutrition and reduces steroid use

  Fahy, A. S., Potter, D. D., Ravi, A., Reissis, Y., Faubion, W. A. & Tung, J., 2017, (Accepted/In press) In: Journal of Pediatric Surgery.

  Research output: Contribution to journal › Article › peer-review

  • Ileostomy
  • Colectomy
  • Colitis
  • Steroids
  • Pediatrics
  3 Scopus citations

• Comparison of Methods for Analyzing Human Adipose Tissue Macrophage Content

  Morgan-Bathke, M., Harteneck, D., Jaeger, P., Sondergaard, E., Karwoski, R., Espinosa De Ycaza, A., Carranza-Leon, B. G., Faubion, W. A., Oliveira, A. M. & Jensen, M. D., Dec 2017, In: Obesity. 25, 12, p. 2100-2107 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Adipose Tissue
  • Macrophages
  • Immunohistochemistry
  • Flow Cytometry
  • Real-Time Polymerase Chain Reaction
  7 Scopus citations

• Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC

  Colombel, J. F., Keir, M. E., Scherl, A., Zhao, R., de Hertogh, G., Faubion, W. A. & Lu, T. T., Dec 1 2017, In: Gut. 66, 12

  Research output: Contribution to journal › Article › peer-review

  • Patient Reported Outcome Measures
  • Hemorrhage
  • Histology
  • Leukocyte L1 Antigen Complex
  • Endoscopy
  55 Scopus citations

• Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease

  Walters, T. D., Faubion, W. A., Griffiths, A. M., Baldassano, R. N., Escher, J., Ruemmele, F. M., Hyams, J. S., Lazar, A., Eichner, S., Huang, B., Li, Y. & Thakkar, R. B., Jun 1 2017, In: Inflammatory bowel diseases. 23, 6, p. 967-975 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adalimumab
  • Crohn Disease
  • Growth
  • Child
  • Pediatric Crohn's disease
  8 Scopus citations

• Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia

  Amadi, B., Besa, E., Zyambo, K., Kaonga, P., Louis-Auguste, J., Chandwe, K., Tarr, P. I., Denno, D. M., Nataro, J. P., Faubion, W., Sailer, A., Yeruva, S., Brantner, T., Murray, J., Prendergast, A. J., Turner, J. R. & Kelly, P., Aug 2017, In: EBioMedicine. 22, p. 191-199 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Claudin-4
  • Mucous Membrane
  • Gliadin
  • Zambia
  • Biopsy
  19 Scopus citations

• Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease

  Hyams, J. S., Dubinsky, M. C., Baldassano, R. N., Colletti, R. B., Cucchiara, S., Escher, J., Faubion, W., Fell, J., Gold, B. D., Griffiths, A., Koletzko, S., Kugathasan, S., Markowitz, J., Ruemmele, F. M., Veereman, G., Winter, H., Masel, N., Shin, C. R., Tang, K. L. & Thayu, M., Jun 2017, In: Gastroenterology. 152, 8, p. 1901-1914.e3

  Research output: Contribution to journal › Article › peer-review

  • Hemophagocytic Lymphohistiocytosis
  • Infliximab
  • Inflammatory Bowel Diseases
  • Pediatrics
  • Neoplasms
  105 Scopus citations

• Long-Term Efficacy and Safety of Adalimumab in Pediatric Patients with Crohn's Disease

  Faubion, W. A., Dubinsky, M., Ruemmele, F. M., Escher, J., Rosh, J., Hyams, J. S., Eichner, S., Li, Y., Reilly, N., Thakkar, R. B., Robinson, A. M. & Lazar, A., Mar 1 2017, In: Inflammatory bowel diseases. 23, 3, p. 453-460 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Adalimumab
  • Crohn Disease
  • Pediatrics
  • Safety
  • Pediatric Crohn's disease
  23 Scopus citations

• Measurement of gut permeability using fluorescent tracer agent technology

  Dorshow, R. B., Hall-Moore, C., Shaikh, N., Talcott, M. R., Faubion, W. A., Rogers, T. E., Shieh, J. J., Debreczeny, M. P., Johnson, J. R., Dyer, R. B., Singh, R. J. & Tarr, P. I., Dec 1 2017, In: Scientific reports. 7, 1, 10888.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescent Dyes
  • Sugars
  • Permeability
  • Technology
  • Indomethacin
  8 Scopus citations

• Targeting Specific Immunologic Pathways in Crohn's Disease

  Ramos, G. P., Faubion, W. A. & Papadakis, K., 2017, (Accepted/In press) In: Gastroenterology Clinics of North America.

  Research output: Contribution to journal › Article › peer-review

  • Crohn Disease
  • Integrins
  • Cytokines
  • Leukocytes
  • Interleukin-23
  4 Scopus citations

• The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)

  Sarmento, O. F., Svingen, P. A., Xiong, Y., Sun, Z., Bamidele, A. O., Mathison, A. J., Smyrk, T. C., Nair, A. A., Gonzalez, M. M., Sagstetter, M. R., Baheti, S., McGovern, D. P. B., Friton, J. J., Papadakis, K. A., Gautam, G., Xavier, R. J., Urrutia, R. A. & Faubion, W. A., Jan 13 2017, In: Journal of Biological Chemistry. 292, 2, p. 706-722 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Enhancer of Zeste Homolog 2 Protein
  • Histone Methyltransferases
  • Inflammatory Bowel Diseases
  • T-cells
  • Regulatory T-Lymphocytes
  26 Scopus citations
• 2016

  Closure of a recurrent bronchopleural fistula using a matrix seeded with patient-derived mesenchymal stem cells

  Aho, J. M., Dietz, A. B., Radel, D. J., Butler, G. W., Thomas, M., Nelson, T. J., Carlsen, B. T., Cassivi, S. D., Resch, Z. T., Faubion, W. A. & Wigle, D. A., Oct 1 2016, In: Stem Cells Translational Medicine. 5, 10, p. 1375-1379 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesenchymal Stem Cells
  • Fistula
  • Abdominal Fat
  • Osteocytes
  • Pneumonectomy
  14 Scopus citations

• Efficacy and safety of escalation of adalimumab therapy to weekly dosing in pediatric patients with Crohn's disease

  Dubinsky, M. C., Rosh, J., Faubion, W. A., Kierkus, J., Ruemmele, F., Hyams, J. S., Eichner, S., Li, Y., Huang, B., Mostafa, N. M., Lazar, A. & Thakkar, R. B., Mar 9 2016, In: Inflammatory bowel diseases. 22, 4, p. 886-893 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Adalimumab
  • Crohn Disease
  • Pediatrics
  • Safety
  • Therapeutics
  20 Scopus citations

• Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ

  Velez, G., Lin, M., Christensen, T., Faubion, W. A., Lomberk, G. & Urrutia, R., Jan 1 2016, In: Journal of Molecular Modeling. 22, 1, p. 1-17 17 p., 12.

  Research output: Contribution to journal › Article › peer-review

  • Proteins
  • proteins
  • chromatin
  • Molecular dynamics
  • therapy
  10 Scopus citations

• Improving the detection of environmental enteric dysfunction: A lactulose, rhamnose assay of intestinal permeability in children aged under 5 years exposed to poor sanitation and hygiene

  Faubion, W. A., Camilleri, M., Murray, J. A., Kelly, P., Amadi, B., Kosek, M. N., Enders, F., Larson, J., Grover, M., Boe, G., Dyer, R. & Singh, R., 2016, In: BMJ Global Health. 1, 1, e000066.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rhamnose
  • Lactulose
  • Sanitation
  • Hygiene
  • Zambia
  22 Scopus citations
• 2015

  A Novel Role for Kruppel-like Factor 14 (KLF14) in T-Regulatory Cell Differentiation

  Sarmento, O. F., Svingen, P. A., Xiong, Y., Xavier, R. J., McGovern, D., Smyrk, T. C., Papadakis, K. A., Urrutia, R. A. & Faubion, W. A., Mar 1 2015, In: CMGH. 1, 2, p. 188-202.e4

  Research output: Contribution to journal › Article › peer-review

  • Kruppel-Like Transcription Factors
  • Forkhead Transcription Factors
  • Cell Differentiation
  • Demethylation
  • Chromatin Immunoprecipitation
  15 Scopus citations

• Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort

  Oliva-Hemker, M., Hutfless, S., Al Kazzi, E. S., Lerer, T., Mack, D., Leleiko, N., Griffiths, A., Cabrera, J., Otley, A., Rick, J., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Carvalho, R., Keljo, D., Pfefferkorn, M., Faubion, W., Kappelman, M. & 4 others, Sudel, B., Schaefer, M. E., Markowitz, J. & Hyams, J. S., Sep 1 2015, In: Journal of Pediatrics. 167, 3, p. 527-532.e3

  Research output: Contribution to journal › Article › peer-review

  • Inflammatory Bowel Diseases
  • Crohn Disease
  • Child
  • Ulcerative Colitis
  • Phenotype
  48 Scopus citations

• Concomitant Use of Immunomodulators Affects the Durability of Infliximab Therapy in Children With Crohn's Disease

  Grossi, V., Lerer, T., Griffiths, A., LeLeiko, N., Cabrera, J., Otley, A., Rick, J., Mack, D., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Boyle, B., Oliva-Hemker, M., Keljo, D., Pfefferkorn, M., Faubion, W., Kappelman, M. D., Sudel, B. & 2 others, Markowitz, J. & Hyams, J. S., Oct 1 2015, In: Clinical Gastroenterology and Hepatology. 13, 10, p. 1748-1756 9 p., 54359.

  Research output: Contribution to journal › Article › peer-review

  • Infliximab
  • Immunologic Factors
  • Crohn Disease
  • Child
  • Therapeutics
  49 Scopus citations

• Idiopathic inflammatory demyelinating disease of the central nervous system in patients with inflammatory bowel disease: Retrospective analysis of 9095 patients

  De Felice, K. M., Novotna, M., Enders, F. T., Faubion, W. A., Tremaine, W. J., Kantarci, O. H. & Raffals, L. E., Jan 1 2015, In: Alimentary Pharmacology and Therapeutics. 41, 1, p. 99-107 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Demyelinating Diseases
  • Inflammatory Bowel Diseases
  • Central Nervous System
  • Ulcerative Colitis
  • Crohn Disease
  8 Scopus citations

• Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation

  Papadakis, K. A., Krempski, J., Svingen, P., Xiong, Y., Sarmento, O. F., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., 2015, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 11, p. G900-G909

  Research output: Contribution to journal › Article › peer-review

  • Colitis
  • Macrophages
  • Anti-Inflammatory Agents
  • Phenotype
  • Macrophage Activation
  11 Scopus citations

• Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8⁺ T lymphocytes

  Papadakis, K. A., Krempski, J., Reiter, J., Svingen, P., Xiong, Y., Sarmento, O. F., Huseby, A., Johnson, A. J., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., 2015, In: American Journal of Physiology - Cell Physiology. 308, 5, p. C362-C371

  Research output: Contribution to journal › Article › peer-review

  • Growth Factor Receptors
  • Transforming Growth Factors
  • T-Lymphocytes
  • T-box transcription factor TBX21
  • Spleen
  15 Scopus citations

• Phenotypic characterization of mice carrying homozygous deletion of KLF11, a gene in which mutations cause human neonatal and MODY VII diabetes

  Mathison, A., Escande, C., Calvo, E., Seo, S., White, T., Salmonson, A., Faubion, W. A., Buttar, N., Iovanna, J., Lomberk, G., Chini, E. N. & Urrutia, R., Oct 1 2015, In: Endocrinology. 156, 10, p. 3581-3595 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Type 2 Diabetes Mellitus
  • Mutation
  • Insulin Resistance
  • Genes
  • Mason-Type Diabetes
  4 Scopus citations

• Stem cells for murine interstitial cells of Cajal suppress cellular immunity and colitis via prostaglandin E₂ secretion

  Dave, M., Hayashi, Y., Gajdos, G. B., Smyrk, T. C., Svingen, P. A., Kvasha, S. M., Lorincz, A., Dong, H., Faubion, W. A. & Ordog, T., May 1 2015, In: Gastroenterology. 148, 5, p. 978-990 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Interstitial Cells of Cajal
  • Colitis
  • Dinoprostone
  • Cellular Immunity
  • Stem Cells
  19 Scopus citations
• 2014

  Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer

  Li, H., Chan, L., Bartuzi, P., Melton, S. D., Weber, A., Ben-Shlomo, S., Varol, C., Raetz, M., Mao, X., Starokadomskyy, P., Van Sommeren, S., Mokadem, M., Schneider, H., Weisberg, R., Westra, H. J., Esko, T., Metspalu, A., Kumar, V., Faubion, W. A., Yarovinsky, F. & 9 others, Hofker, M., Wijmenga, C., Kracht, M., Franke, L., Aguirre, V., Weersma, R. K., Gluck, N., Van De Sluis, B. & Burstein, E., Jul 2014, In: Gastroenterology. 147, 1, p. 184-195.e3

  Research output: Contribution to journal › Article › peer-review

  • Colitis
  • Copper
  • Inflammatory Bowel Diseases
  • Inflammation
  • Knockout Mice
  17 Scopus citations

• Differential coupling of KLF10 to sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene

  Xiong, Y., Svingen, P. A., Sarmento, O. O., Smyrk, T. C., Dave, M., Khanna, S., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Sep 15 2014, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 6, p. R608-R620

  Research output: Contribution to journal › Article › peer-review

  • p300-CBP-associated factor
  • Kruppel-Like Transcription Factors
  • Factor X
  • Transcription Factors
  • Genes
  17 Scopus citations

• Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease

  Okou, D. T., Mondal, K., Faubion, W. A., Kobrynski, L. J., Denson, L. A., Mulle, J. G., Ramachandran, D., Xiong, Y., Svingen, P., Patel, V., Bose, P., Waters, J. P., Prahalad, S., Cutler, D. J., Zwick, M. E. & Kugathasan, S., May 2014, In: Journal of pediatric gastroenterology and nutrition. 58, 5, p. 561-568 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Exome
  • Inflammatory Bowel Diseases
  • Whole Exome Sequencing
  • Mutation
  • Forkhead Transcription Factors
  34 Scopus citations

• Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression

  Mills, L. D., Zhang, L., Marler, R., Svingen, P., Fernandez-Barrena, M. G., Dave, M., Bamlet, W., McWilliams, R. R., Petersen, G. M., Faubion, W. & Fernandez-Zapico, M. E., Jun 6 2014, In: Journal of Biological Chemistry. 289, 23, p. 16516-16525 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Tumors
  • Pancreatic Neoplasms
  • Transcription Factors
  • Ligands
  • Knockout Mice
  14 Scopus citations