• 6620 Citations
  • 40 Scopus h-Index
19972020

Research output per year

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Research Output

2015

Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation

Papadakis, K., Krempski, J., Svingen, P., Xiong, Y., Sarmento, O. F., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 11, p. G900-G909

Research output: Contribution to journalArticle

9 Scopus citations

Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes

Papadakis, K. A., Krempski, J., Reiter, J., Svingen, P., Xiong, Y., Sarmento, O. F., Huseby, A., Johnson, A. J., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Jan 1 2015, In : American Journal of Physiology - Cell Physiology. 308, 5, p. C362-C371

Research output: Contribution to journalArticle

10 Scopus citations

Mesenchymal stem cell therapy for inflammatory bowel disease: A systematic review and meta-analysis

Dave, M., Mehta, K., Luther, J., Baruah, A., Dietz, A. B. & Faubion, W. A., Jul 25 2015, In : Inflammatory bowel diseases. 21, 11, p. 2696-2707 12 p.

Research output: Contribution to journalReview article

39 Scopus citations

Phenotypic characterization of mice carrying homozygous deletion of KLF11, a gene in which mutations cause human neonatal and MODY VII diabetes

Mathison, A., Escande, C., Calvo, E., Seo, S., White, T., Salmonson, A., Faubion, W. A., Buttar, N. S., Iovanna, J., Lomberk, G., Chini, E. N. & Urrutia, R., Oct 1 2015, In : Endocrinology. 156, 10, p. 3581-3595 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Stem cells for murine interstitial cells of Cajal suppress cellular immunity and colitis via prostaglandin E<inf>2</inf> secretion

Dave, M., Hayashi, Y., Gajdos, G. B., Smyrk, T. C., Svingen, P. A., Kvasha, S. M., Lorincz, A., Dong, H. M., Faubion, W. A. & Ordog, T., May 1 2015, In : Gastroenterology. 148, 5, p. 978-990 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
2014

Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer

Li, H., Chan, L., Bartuzi, P., Melton, S. D., Weber, A., Ben-Shlomo, S., Varol, C., Raetz, M., Mao, X., Starokadomskyy, P., Van Sommeren, S., Mokadem, M., Schneider, H., Weisberg, R., Westra, H. J., Esko, T., Metspalu, A., Kumar, V., Faubion, W. A., Yarovinsky, F. & 9 others, Hofker, M., Wijmenga, C., Kracht, M., Franke, L., Aguirre, V., Weersma, R. K., Gluck, N., Van De Sluis, B. & Burstein, E., Jul 2014, In : Gastroenterology. 147, 1, p. 184-195.e3

Research output: Contribution to journalArticle

15 Scopus citations

Differential coupling of KLF10 to sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene

Xiong, Y., Svingen, P. A., Sarmento, O. O., Smyrk, T. C., Dave, M., Khanna, S., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Sep 15 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 6, p. R608-R620

Research output: Contribution to journalArticle

16 Scopus citations

Erratum: EMerging BiomARKers in inflammatory bowel disease (EMBARK) study identifies fecal calprotectin, serum MMP9, and serum IL-22 as a novel combination of biomarkers for crohn's disease activity: Role of cross-sectional imaging (American Journal of Gastroenterology (2013) 108 (1891-1900) DOI: 10.1038/ajg.2013.354)

Faubion, W. A., Fletcher, J. G., O'Byrne, S., Feagan, B. G., De Villiers, W. J. S., Salzberg, B., Plevy, S., Proctor, D. D., Valentine, J. F., Higgins, P. D., Harris, J. M., Diehl, L., Wright, L., Wei Tew, G., Luca, D., Basu, K. & Keir, M. E., May 2014, In : American Journal of Gastroenterology. 109, 5, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease

Okou, D. T., Mondal, K., Faubion, W. A., Kobrynski, L. J., Denson, L. A., Mulle, J. G., Ramachandran, D., Xiong, Y., Svingen, P., Patel, V., Bose, P., Waters, J. P., Prahalad, S., Cutler, D. J., Zwick, M. E. & Kugathasan, S., May 2014, In : Journal of pediatric gastroenterology and nutrition. 58, 5, p. 561-568 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Immunology of Inflammatory Bowel Disease and Molecular Targets for Biologics

Dave, M., Papadakis, K. A. & Faubion, W. A., Sep 2014, In : Gastroenterology Clinics of North America. 43, 3, p. 405-424 20 p.

Research output: Contribution to journalReview article

30 Scopus citations

Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression

Mills, L. D., Zhang, L., Marler, R., Svingen, P., Fernandez-Barrena, M. G., Dave, M., Bamlet, W., McWilliams, R. R., Petersen, G. M., Faubion, W. & Fernandez-Zapico, M. E., Jun 6 2014, In : Journal of Biological Chemistry. 289, 23, p. 16516-16525 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Liver enzyme elevations within 3 months of diagnosis of inflammatory bowel disease and likelihood of liver disease

Goyal, A., Hyams, J. S., Lerer, T., Leleiko, N. S., Otley, A. R., Griffiths, A. M., Rosh, J. R., Cabrera, J. M., Oliva-Hemker, M. M., Mack, D. R., Rick, J. N., Pfefferkorn, M. D., Carvalho, R., Grossman, A. B., Hitch, M. C., Sudel, B., Kappelman, M. D., Saeed, S. A., Faubion, W. A., Schaefer, M. E. & 2 others, Markowitz, J. F. & Keljo, D. J., Sep 2014, In : Journal of pediatric gastroenterology and nutrition. 59, 3, p. 321-323 3 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

A case of esophageal pseudomembranes

Hart, P. A., Owens, V. L. & Faubion, W. A., Aug 2013, In : Gastroenterology. 145, 2, p. 290+489-490

Research output: Contribution to journalComment/debate

Cytomegalovirus infection of the ileoanal pouch: Clinical characteristics and outcomes

McCurdy, J. D., Loftus, E. V., Tremaine, W. J., Smyrk, T. C., Bruining, D. H., Pardi, D. S., Raffals, L. E., Kisiel, J. B., Coelho-Prabhu, N., Kane, S. V., Faubion, W. A. & Papadakis, K. A., Oct 1 2013, In : Inflammatory bowel diseases. 19, 11, p. 2394-2399 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Duodenal intraepithelial lymphocytosis with normal villous architecture in pediatric patients: Mayo clinic experience, 2000-2009

Shmidt, E., Smyrk, T. C., Faubion, W. A. & Oxentenko, A. S., Jan 1 2013, In : Journal of pediatric gastroenterology and nutrition. 56, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Emerging biomarkers in inflammatory bowel disease (embark) study identifies fecal calprotectin, serum mmp9, and serum il-22 as a novel combination of biomarkers for crohn's disease activity: Role of cross-sectional imaging

Faubion, W. A., Fletcher, J. G., O'Byrne, S., Feagan, B. G., De Villiers, W. J., Salzberg, B., Plevy, S., Proctor, D. D., Valentine, J. F., Higgins, P. D., Harris, J. M., Diehl, L., Wright, L., Tew, G. W., Luca, D., Basu, K. & Keir, M. E., Dec 2013, In : American Journal of Gastroenterology. 108, 12, p. 1891-1900 10 p.

Research output: Contribution to journalArticle

64 Scopus citations

Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

Grzenda, A., Lomberk, G., Svingen, P., Mathison, A., Calvo, E., Iovanna, J., Xiong, Y., Faubion, W. & Urrutia, R., Mar 4 2013, In : Epigenetics and Chromatin. 6, 1, 3.

Research output: Contribution to journalArticle

20 Scopus citations

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele

Kauder, S. E., Santell, L., Mai, E., Wright, L. Y., Luis, E., N'Diaye, E. N., Lutman, J., Ratti, N., Sa, S. M., Maun, H. R., Stefanich, E., Gonzalez, L. C., Graham, R. R., Diehl, L., Faubion, W. A., Keir, M. E., Young, J., Chaudhuri, A., Lazarus, R. A. & Egen, J. G., Dec 23 2013, In : PloS one. 8, 12, e83958.

Research output: Contribution to journalArticle

10 Scopus citations

Gut immunity and inflammatory bowel disease

Faubion, W. A., Jan 1 2013, Pediatric Inflammatory Bowel Disease, Second Edition. Springer New York, p. 13-23 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Incidence, clinical characteristics, and natural history of pediatric IBD in Wisconsin: A population-based epidemiological study

Adamiak, T., Walkiewicz-Jedrzejczak, D., Fish, D., Brown, C., Tung, J., Khan, K., Faubion, W., Park, R., Heikenen, J., Yaffee, M., Rivera-Bennett, M. T., Wiedkamp, M., Stephens, M., Noel, R., Nugent, M., Nebel, J., Simpson, P., Kappelman, M. D. & Kugathasan, S., May 1 2013, In : Inflammatory bowel diseases. 19, 6, p. 1218-1223 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Letters to the editors

Kane, S. V., Neis, B., Becker, B. D., Bruining, D., Faubion, W. A., Kisiel, J., Loftus, E. V., Pardi, D., Raffals, L., Schroeder, K. & Tremaine, W. J., Dec 1 2013, In : Alimentary Pharmacology and Therapeutics. 38, 11-12, 1 p.

Research output: Contribution to journalLetter

Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis

Zeisler, B., Lerer, T., Markowitz, J., MacK, D., Griffiths, A., Bousvaros, A., Keljo, D., Rosh, J., Evans, J., Kappelman, M., Otley, A., Kay, M., Grossman, A., Saeed, S., Carvalho, R., Oliva-Hemker, M., Faubion, W., Sudel, B., Pfefferkorn, M., Ashai-Khan, F. & 2 others, Leleiko, N. & Hyams, J., Jan 1 2013, In : Journal of pediatric gastroenterology and nutrition. 56, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Outcomes of patients with microscopic colitis treated with corticosteroids: A population-based study

Gentile, N. M., Abdalla, A. A., Khanna, S., Smyrk, T. C., Tremaine, W. J., Faubion, W. A., Kammer, P. P., Sandborn, W. J., Loftus, E. V. & Pardi, D. S., Feb 1 2013, In : American Journal of Gastroenterology. 108, 2, p. 256-259 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Regulatory T cell kinetics in the peripheral blood of patients with Crohn's disease

Rahman, M. K., Offord, C. P., Khanna, S., Ford, G. C., Perrson, X. M. T., Svingen, P. A., Xiong, Y., Bajzer, Z. & Faubion, W. A., Feb 1 2013, In : Human Immunology. 74, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Risk factors for lymphoma in patients with inflammatory bowel disease: A case-control study

Afif, W., Sandborn, W. J., Faubion, W. A., Rahman, M., Harmsen, S. W., Zinsmeister, A. R. & Loftus, E. V., Jun 1 2013, In : Inflammatory bowel diseases. 19, 7, p. 1384-1389 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

Mathison, A., Grzenda, A., Lomberk, G., Velez, G., Buttar, N., Tietz, P., Hendrickson, H., Liebl, A., Xiong, Y. Y., Gores, G., Fernandez-Zapico, M., LaRusso, N. F., Faubion, W., Shah, V. H. & Urrutia, R., Sep 16 2013, In : PloS one. 8, 9, e75311.

Research output: Contribution to journalArticle

18 Scopus citations

The epidemiology of clostridium difficile infection in children: A population-based study

Khanna, S., Baddour, L. M., Huskins, W. C., Kammer, P. P., Faubion, W. A., Zinsmeister, A. R., Harmsen, W. S. & Pardi, D. S., May 15 2013, In : Clinical Infectious Diseases. 56, 10, p. 1401-1406 6 p.

Research output: Contribution to journalArticle

129 Scopus citations

Validation of the Ulcerative Colitis Colonoscopic Index of Severity and Its Correlation With Disease Activity Measures

Samuel, S., Bruining, D. H., Loftus, E. V., Thia, K. T., Schroeder, K. W., Tremaine, W. J., Faubion, W. A., Kane, S. V., Pardi, D. S., de Groen, P. C., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Jan 2013, In : Clinical Gastroenterology and Hepatology. 11, 1, p. 49-54.e1

Research output: Contribution to journalArticle

67 Scopus citations
2012

Benefit of computed tomography enterography in Crohn's disease: Effects on patient management and physician level of confidence

Bruining, D. H., Siddiki, H. A., Fletcher, J. G., Sandborn, W. J., Fidler, J. L., Huprich, J. E., Mandrekar, J. N., Harmsen, W. S., Evans, P. E., Faubion, W. A., Hanson, K. A., Ingle, S. B., Pardi, D. S., Schroeder, K. W., Tremaine, W. J. & Loftus, E. V., Feb 1 2012, In : Inflammatory bowel diseases. 18, 2, p. 219-225 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Biomarkers of therapeutic response in the IL-23 pathway in inflammatory bowel disease

Cayatte, C., Joyce-Shaikh, B., Vega, F., Boniface, K., Grein, J., Murphy, E., Blumenschein, W. M., Chen, S., Malinao, M. C., Basham, B., Pierce, R. H., Bowman, E. P., McKenzie, B. S., Elson, C. O., Faubion, W. A., Malefyt, R. D. W., Kastelein, R. A., Cua, D., McClanahan, T. K. & Beaumont, M., Jun 11 2012, In : Clinical and translational gastroenterology. 3, e10.

Research output: Contribution to journalArticle

38 Scopus citations

Concomitant therapy with methotrexate and anti-TNF-α in pediatric patients with refractory crohn's colitis: A case series

Absah, I. & Faubion, W. A., Aug 1 2012, In : Inflammatory bowel diseases. 18, 8, p. 1488-1492 5 p.

Research output: Contribution to journalReview article

14 Scopus citations

Health supervision in the management of children and adolescents with IBD: NASPGHAN recommendations

Rufo, P. A., Denson, L. A., Sylvester, F. A., Szigethy, E., Sathya, P., Lu, Y., Wahbeh, G. T., Sena, L. M. & Faubion, W. A., Jul 1 2012, In : Journal of pediatric gastroenterology and nutrition. 55, 1, p. 93-108 16 p.

Research output: Contribution to journalArticle

56 Scopus citations

MR enterography in pediatric inflammatory bowel disease: Retrospective assessment of patient tolerance, image quality, and initial performance estimates

Absah, I., Bruining, D. H., Matsumoto, J. M., Weisbrod, A. J., Fletcher, J. G., Fidler, J. L. & Faubion, W. A., Sep 1 2012, In : American Journal of Roentgenology. 199, 3, p. W367-W375

Research output: Contribution to journalArticle

40 Scopus citations

Natalizumab for moderate to severe Crohn's disease in clinical practice: The Mayo Clinic Rochester experience

Kane, S. V., Horst, S., Sandborn, W. J., Becker, B., Neis, B., Moscandrew, M., Hanson, K. A., Tremaine, W. J., Bruining, D. H., Faubion, W. A., Pardi, D. S., Harmsen, W. S., Zinsmeister, A. R. & Loftus, E. V., Dec 1 2012, In : Inflammatory bowel diseases. 18, 12, p. 2203-2208 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Pediatric chronic ulcerative colitis: Does infliximab increase post-ileal pouch anal anastomosis complications?

Kennedy, R., Potter, D. D., Moir, C., Zarroug, A. E., Faubion, W. & Tung, J., Jan 1 2012, In : Journal of pediatric surgery. 47, 1, p. 199-203 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner

Xiong, Y., Khannas, S., Grzenda, A. L., Sarmento, O. F., Svingen, P. A., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Oct 5 2012, In : Journal of Biological Chemistry. 287, 41, p. 34372-34385 14 p.

Research output: Contribution to journalArticle

36 Scopus citations

Safety and efficacy of adalimumab for moderate to severe crohn's disease in children

Hyams, J. S., Griffiths, A., Markowitz, J., Baldassano, R. N., Faubion, W. A., Colletti, R. B., Dubinsky, M., Kierkus, J., Rosh, J., Wang, Y., Huang, B., Bittle, B., Marshall, M. & Lazar, A., Aug 2012, In : Gastroenterology. 143, 2, p. 365-374.e2

Research output: Contribution to journalArticle

140 Scopus citations

Signaling lymphocyte activation molecule regulates development of colitis in mice

Van Driel, B., Liao, G., Romero, X., O'Keeffe, M. S., Wang, G., Faubion, W. A., Berger, S. B., Magelky, E. M., Manocha, M., Azcutia, V., Grisham, M., Luscinskas, F. W., Mizoguchi, E., De Waal Malefyt, R., Reinecker, H. C., Bhan, A. K., Wang, N. & Terhorst, C., Dec 2012, In : Gastroenterology. 143, 6, p. 1544-1554.e7

Research output: Contribution to journalArticle

11 Scopus citations

Single-incision laparoscopic colon and rectal surgery for pediatric inflammatory bowel disease and polyposis syndromes

Potter, D. D., Tung, J., Faubion, W. A. & Moir, C., Mar 1 2012, In : Journal of Laparoendoscopic and Advanced Surgical Techniques. 22, 2, p. 203-207 5 p.

Research output: Contribution to journalReview article

14 Scopus citations
2011

Measurement of disease activity in ulcerative colitis: Interobserver agreement and predictors of severity

Thia, K. T., Loftus, E. V., Pardi, D. S., Kane, S. V., Faubion, W. A., Tremaine, W. J., Schroeder, K. W., Harmsen, S. W., Zinsmeister, A. R. & Sandborn, W. J., Jun 1 2011, In : Inflammatory bowel diseases. 17, 6, p. 1257-1264 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Short CDAI: Development and validation of a shortened and simplified Crohn's disease activity index

Thia, K., Faubion, W. A., Loftus, E. V., Persson, T., Persson, A. & Sandborn, W. J., Jan 2011, In : Inflammatory bowel diseases. 17, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Single molecule measurements of tumor necrosis factor α and interleukin-6 in the plasma of patients with Crohn's disease

Song, L., Hanlon, D. W., Chang, L., Provuncher, G. K., Kan, C. W., Campbell, T. G., Fournier, D. R., Ferrell, E. P., Rivnak, A. J., Pink, B. A., Minnehan, K. A., Patel, P. P., Wilson, D. H., Till, M. A., Faubion, W. A. & Duffy, D. C., Sep 30 2011, In : Journal of Immunological Methods. 372, 1-2, p. 177-186 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
2010

Adalimumab for Crohns disease in clinical practice at Mayo clinic: The first 118 patients

Swoger, J. M., Loftus, E. V., Tremaine, W. J., Faubion, W. A., Pardi, D. S., Kane, S. V., Hanson, K. A., Harmsen, W. S., Zinsmeister, A. R. & Sandborn, W. J., Nov 1 2010, In : Inflammatory bowel diseases. 16, 11, p. 1912-1921 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease

Afif, W., Loftus, E. V., Faubion, W. A., Kane, S. V., Bruining, D. H., Hanson, K. A. & Sandborn, W. J., May 1 2010, In : American Journal of Gastroenterology. 105, 5, p. 1133-1139 7 p.

Research output: Contribution to journalArticle

384 Scopus citations

Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver

Jagavelu, K., Routray, C., Shergill, U., O'Hara, S. P., Faubion, W. & Shah, V. H., Aug 1 2010, In : Hepatology. 52, 2, p. 590-601 12 p.

Research output: Contribution to journalArticle

82 Scopus citations

Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion

Cao, T., Wenzel, S. E., Faubion, W. A., Harriman, G. & Li, L., Sep 1 2010, In : Clinical Immunology. 136, 3, p. 329-337 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Recurrence and impact of postoperative prophylaxis in laparoscopically treated primary ileocolic crohn disease

Malireddy, K., Larson, D. W., Sandborn, W. J., Loftus, E. V., Faubion, W. A., Pardi, D. S., Qin, R., Gullerud, R. E., Cima, R. R., Wolff, B. & Dozois, E. J., Jan 1 2010, In : Archives of Surgery. 145, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

Berger, S. B., Romero, X., Ma, C., Wang, G., Faubion, W. A., Liao, G., Compeer, E., Keszei, M., Rameh, L., Wang, N., Boes, M., Regueiro, J. R., Reinecker, H. C. & Terhorst, C., Oct 1 2010, In : Nature immunology. 11, 10, p. 920-927 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival

Rahman, M. K., Midtling, E. H., Svingen, P. A., Xiong, Y., Bell, M. P., Tung, J., Smyrk, T., Egan, L. J. & Faubion, W. A., Jun 15 2010, In : Journal of Immunology. 184, 12, p. 7247-7256 10 p.

Research output: Contribution to journalArticle

44 Scopus citations