• 6485 Citations
  • 38 Scopus h-Index
19972021

Research output per year

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Research Output

2019

A Comprehensive Approach to Pouch Disorders

Quinn, K. P., Lightner, A., Faubion, W. A. & Raffals, L. E. H., Feb 21 2019, In : Inflammatory bowel diseases. 25, 3, p. 460-471 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study

Muñiz Pedrogo, D. A., Chen, J., Hillmann, B., Jeraldo, P., Al-Ghalith, G., Taneja, V., Davis, J. M., Knights, D., Nelson, H., Faubion, W. A., Raffals, L. & Kashyap, P. C., Apr 11 2019, In : Inflammatory bowel diseases. 25, 5, p. 902-913 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn's patients

Lightner, A., McKenna, N. P., Alsughayer, A., Loftus, Jr, E. V., Raffals, L. E. H., Faubion, W. A. & Moir, C., Jan 1 2019, In : Journal of pediatric surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Designing clinical trials in paediatric inflammatory bowel diseases: A PIBDnet commentary

Turner, D., Griffiths, A. M., Wilson, D., Mould, D. R., Baldassano, R. N., Russell, R. K., Dubinsky, M., Heyman, M. B., De Ridder, L., Hyams, J., Martin De Carpi, J., Conklin, L., Faubion, W. A., Koletzko, S., Bousvaros, A. & Ruemmele, F. M., Jan 1 2019, In : Gut.

Research output: Contribution to journalArticle

2 Scopus citations

Disruption of FOXP3–EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation

Bamidele, A. O., Svingen, P. A., Sagstetter, M. R., Sarmento, O. F., Gonzalez, M., Braga Neto, M. B., Kugathasan, S., Lomberk, G., Urrutia, R. A. & Faubion, W. A., Jan 1 2019, In : CMGH. 7, 1, p. 55-71 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Early Results of a Phase I Trial Using an Adipose-Derived Mesenchymal Stem Cell-Coated Fistula Plug for the Treatment of Transsphincteric Cryptoglandular Fistulas

Dozois, E., Lightner, A., Mathis, K. L., Chua, H. K., Kelley, S. R., Fletcher, J. G., Dietz, A. B., Friton, J. J., Butler, G. W. & Faubion, W. A., May 1 2019, In : Diseases of the colon and rectum. 62, 5, p. 615-622 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Loss of rnf40 decreases nf-κb activity in colorectal cancer cells and reduces colitis burden in mice

Kosinsky, R. L., Chua, R. L., Qui, M., Saul, D., Mehlich, D., Ströbel, P., Schildhaus, H. U., Wegwitz, F., Faubion, W. A. & Johnsen, S., Mar 26 2019, In : Journal of Crohn's and Colitis. 13, 3, p. 362-373 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis

Abe, J. I., Ko, K. A., Kotla, S., Wang, Y., Paez-Mayorga, J., Shin, I. J., Imanishi, M., Vu, H. T., Tao, Y., Leiva-Juarez, M. M., Thomas, T. N., Medina, J. L., Won, J. H., Fujii, Y., Giancursio, C. J., McBeath, E., Shin, J. H., Guzman, L., Abe, R. J., Taunton, J. & 6 others, Mochizuki, N., Faubion, W., Cooke, J. P., Fujiwara, K., Evans, S. E. & Le, N. T., Apr 4 2019, In : JCI Insight. 4, 7, e125570.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

Wang, M. H., Friton, J. J., Raffals, L. E. H., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In : Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

Research output: Contribution to journalArticle

1 Scopus citations

Regenerative Materials for Surgical Reconstruction: Current Spectrum of Materials and a Proposed Method for Classification

Sharma, A., Faubion, W. A. & Dietz, A. B., Oct 1 2019, In : Mayo Clinic proceedings. 94, 10, p. 2099-2116 18 p.

Research output: Contribution to journalReview article

Open Access

Update on the Natural Course of Fistulizing Perianal Crohn's Disease in a Population-Based Cohort

Park, S. H., Aniwan, S., Scott Harmsen, W., Tremaine, W. J., Lightner, A., Faubion, W. A. & Loftus, Jr, E. V., May 4 2019, In : Inflammatory bowel diseases. 25, 6, p. 1054-1060 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

Ichikawa, R., Lamb, C. A., Eastham-Anderson, J., Scherl, A., Raffals, L. E. H., Faubion, W. A., Bennett, M. R., Long, A. K., Mansfield, J. C., Kirby, J. A. & Keir, M. E., Nov 9 2018, In : Journal of Crohn's & colitis. 12, 10, p. 1191-1199 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical benefit of capsule endoscopy in Crohn's disease: Impact on patient management and prevalence of proximal small bowel involvement

Hansel, S. L., McCurdy, J. D., Barlow, J. M., Fidler, J., Fletcher, J. G., Becker, B., Prabhu, N. C., Faubion, W. A., Hanson, K. A., Kane, S. V., Kisiel, J. B., Loftus, Jr, E. V., Papadakis, K., Pardi, D. S., Raffals, L. E. H., Schoenoff, S., Tremaine, W. J. & Bruining, D. H., Jan 1 2018, In : Inflammatory Bowel Diseases. 24, 7, p. 1582-1588 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Efficacy of Adalimumab for Treatment of Perianal Fistula in Children with Moderately to Severely Active Crohn's Disease: Results from IMAgINE 1 and IMAgINE 2

Ruemmele, F. M., Rosh, J., Faubion, W. A., Dubinsky, M. C., Turner, D., Lazar, A., Eichner, S., Maa, J. F., Alperovich, G., Robinson, A. M. & Hyams, J. S., Nov 9 2018, In : Journal of Crohn's & colitis. 12, 10, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Epigenetics of gastrointestinal diseases: notes from a workshop

Marks, D. L., Olson, R. L., Urrutia, R., Billadeau, D. D., Roy, N., Calin, G. A., Fabbri, M., Koutsioumpa, M., Iliopoulos, D., Ordog, T., Huebert, R. C., Sarmento, O., Bamidele, A. O., Faubion, W. A., Lomberk, G. L., Siveke, J., Ahuja, N., Iovanna, J., Hlady, R. A., Robertson, K. D. & 3 others, Kisiel, J. B., Pin, C. L. & Fernandez-Zapico, M. E., Apr 3 2018, In : Epigenetics. 13, 4, p. 449-457 9 p.

Research output: Contribution to journalArticle

In-patient outcomes of Hematopoietic Stem Cell Transplantation in Patients with Immune Mediated Inflammatory Diseases: A Nationwide Study

Mehta, K., Jaiswal, P., Briggs, F., Faubion, W. A., Tabibian, J. H., Cominelli, F. & Dave, M., Dec 1 2018, In : Scientific Reports. 8, 1, 6825.

Research output: Contribution to journalArticle

Outcomes of endoscopic therapy for luminal strictures in Crohn's disease

Shivashankar, R., Varayil, J. E., Harmsen, W. S., Faubion, W. A., Song, L. M. W. K., Bruining, D. H., Schroeder, K. W., Kisiel, J. B., Loftus, Jr, E. V. & Prabhu, N. C., Jan 1 2018, In : Inflammatory Bowel Diseases. 24, 7, p. 1575-1581 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Outcomes of treatment for latent tuberculosis infection in patients with inflammatory bowel disease receiving biologic therapy

Ramos, G. P., Stroh, G., Al-Bawardy, B., Faubion, W. A., Papadakis, K. & Escalante, P., Oct 1 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2272-2277 6 p.

Research output: Contribution to journalReview article

3 Scopus citations

The Role of Histone Methyltransferases and Long Non-coding RNAs in the Regulation of T Cell Fate Decisions

Gaballa, J. M., Braga Neto, M. B., Ramos, G. P., Bamidele, A. O., Gonzalez, M. M., Sagstetter, M. R., Sarmento, O. F. & Faubion, W. A., Jan 1 2018, In : Frontiers in Immunology. 9, 1 p.

Research output: Contribution to journalReview article

1 Scopus citations
2017

Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results from the MAL-ED Study

Kosek, M. N., Lee, G. O., Guerrant, R. L., Haque, R., Kang, G., Ahmed, T., Bessong, P., Ali, A., Mduma, E., Peñataro Yori, P., Faubion, W. A., Lima, A. A. M., Paredes Olortegui, M., Mason, C., Babji, S., Singh, R. J., Qureshi, S., Kosek, P. S., Samie, A., Pascal, J. & 7 others, Shrestha, S., McCormick, B. J. J., Seidman, J. C., Lang, D. R., Zaidi, A., Caulfield, L. E. & Gottlieb, M., Jul 1 2017, In : Journal of Pediatric Gastroenterology and Nutrition. 65, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Autologous Mesenchymal Stem Cells, Applied in a Bioabsorbable Matrix, for Treatment of Perianal Fistulas in Patients With Crohn's Disease

Dietz, A. B., Dozois, E., Fletcher, J. G., Butler, G. W., Radel, D., Lightner, A., Dave, M., Friton, J., Nair, A., Camilleri, E. T., Dudakovic, A., van Wijnen, A. J. & Faubion, W. A., Jul 1 2017, In : Gastroenterology. 153, 1, p. 59-62.e2

Research output: Contribution to journalArticle

52 Scopus citations

Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study

Westera, L., Van Viegen, T., Jeyarajah, J., Azad, A., Bilsborough, J., Van Den Brink, G. R., Cremer, J., Danese, S., D'Haens, G., Eckmann, L., Faubion, W. A., Filice, M., Korf, H., McGovern, D., Panes, J., Salas, A., Sandborn, W. J., Silverberg, M. S., Smith, M. I., Vermeire, S. & 8 others, Vetrano, S., Shackelton, L. M., Stitt, L., Jairath, V., Levesque, B. G., Spencer, D. M., Feagan, B. G. & Casteele, N. V., Nov 2 2017, In : Clinical and Translational Gastroenterology. 8, 11, e126.

Research output: Contribution to journalArticle

5 Scopus citations

Colectomy in refractory Crohn's colitis improves nutrition and reduces steroid use

Fahy, A. S., Potter, D. D., Ravi, A., Reissis, Y., Faubion, W. A. & Tung, J., 2017, (Accepted/In press) In : Journal of Pediatric Surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Comparison of Methods for Analyzing Human Adipose Tissue Macrophage Content

Morgan-Bathke, M., Harteneck, D., Jaeger, P., Sondergaard, E., Karwoski, R., Espinosa De Ycaza, A., Carranza-Leon, B. G., Faubion, W. A., Oliveira, A. M. & Jensen, M. D., Dec 1 2017, In : Obesity. 25, 12, p. 2100-2107 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease

Walters, T. D., Faubion, W. A., Griffiths, A. M., Baldassano, R. N., Escher, J., Ruemmele, F. M., Hyams, J. S., Lazar, A., Eichner, S., Huang, B., Li, Y. & Thakkar, R. B., Jun 1 2017, In : Inflammatory Bowel Diseases. 23, 6, p. 967-975 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia

Amadi, B., Besa, E., Zyambo, K., Kaonga, P., Louis-Auguste, J., Chandwe, K., Tarr, P. I., Denno, D. M., Nataro, J. P., Faubion, W. A., Sailer, A., Yeruva, S., Brantner, T., Murray, J. A., Prendergast, A. J., Turner, J. R. & Kelly, P., Aug 1 2017, In : EBioMedicine. 22, p. 191-199 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease

Hyams, J. S., Dubinsky, M. C., Baldassano, R. N., Colletti, R. B., Cucchiara, S., Escher, J., Faubion, W. A., Fell, J., Gold, B. D., Griffiths, A., Koletzko, S., Kugathasan, S., Markowitz, J., Ruemmele, F. M., Veereman, G., Winter, H., Masel, N., Shin, C. R., Tang, K. L. & Thayu, M., Jun 1 2017, In : Gastroenterology. 152, 8, p. 1901-1914.e3

Research output: Contribution to journalArticle

81 Scopus citations

Interdisciplinary Management of Perianal Crohn's Disease

Lightner, A., Faubion, W. A. & Fletcher, J. G., Sep 1 2017, In : Gastroenterology Clinics of North America. 46, 3, p. 547-562 16 p.

Research output: Contribution to journalReview article

1 Scopus citations

Long-Term Efficacy and Safety of Adalimumab in Pediatric Patients with Crohn's Disease

Faubion, W. A., Dubinsky, M., Ruemmele, F. M., Escher, J., Rosh, J., Hyams, J. S., Eichner, S., Li, Y., Reilly, N., Thakkar, R. B., Robinson, A. M. & Lazar, A., Mar 1 2017, In : Inflammatory Bowel Diseases. 23, 3, p. 453-460 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Measurement of gut permeability using fluorescent tracer agent technology

Dorshow, R. B., Hall-Moore, C., Shaikh, N., Talcott, M. R., Faubion, W. A., Rogers, T. E., Shieh, J. J., Debreczeny, M. P., Johnson, J. R., Dyer, R. B., Singh, R. J. & Tarr, P. I., Dec 1 2017, In : Scientific Reports. 7, 1, 10888.

Research output: Contribution to journalArticle

4 Scopus citations

Mesenchymal stem cell injections for the treatment of perianal crohn's disease: What we have accomplished and what we still need to do

Lightner, A. & Faubion, W. A., Oct 1 2017, In : Journal of Crohn's and Colitis. 11, 10, p. 1267-1276 10 p.

Research output: Contribution to journalReview article

6 Scopus citations

MR Imaging of perianal Crohn disease

Sheedy, S. P., Bruining, D. H., Dozois, E., Faubion, W. A. & Fletcher, J. G., Mar 1 2017, In : Radiology. 282, 3, p. 628-645 18 p.

Research output: Contribution to journalReview article

33 Scopus citations

Response

Fletcher, J. G., Bruining, D. H., Faubion, W. A., Dozois, E. & Sheedy, S. P., Sep 1 2017, In : Radiology. 284, 3, p. 921-922 2 p.

Research output: Contribution to journalLetter

Targeting Specific Immunologic Pathways in Crohn's Disease

Ramos, G. P., Faubion, W. A. & Papadakis, K., 2017, (Accepted/In press) In : Gastroenterology Clinics of North America.

Research output: Contribution to journalArticle

4 Scopus citations

The intestinal immune system during homeostasis and inflammatory bowel disease

Hill, D. A. & Faubion, W. A., Jun 6 2017, Pediatric Inflammatory Bowel Disease: Third Edition. Springer International Publishing, p. 15-30 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction

Thompson, A. J., Hughes, M., Anastasova, S., Conklin, L. S., Thomas, T., Leggett, C., Faubion, W. A., Miller, T. J., Delaney, P., Lacombe, F., Loiseau, S., Meining, A., Richards-Kortum, R., Tearney, G. J., Kelly, P. & Yang, G. Z., Dec 1 2017, In : Nature Reviews Gastroenterology and Hepatology. 14, 12, p. 727-738 12 p.

Research output: Contribution to journalReview article

5 Scopus citations

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)

Sarmento, O. F., Svingen, P. A., Xiong, Y., Sun, Z. D., Bamidele, A. O., Mathison, A. J., Smyrk, T. C., Nair, A. A., Gonzalez, M. M., Sagstetter, M. R., Baheti, S., McGovern, D. P. B., Friton, J. J., Papadakis, K., Gautam, G., Xavier, R. J., Urrutia, R. A. & Faubion, W. A., Jan 13 2017, In : Journal of Biological Chemistry. 292, 2, p. 706-722 17 p.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Closure of a recurrent bronchopleural fistula using a matrix seeded with patient-derived mesenchymal stem cells

Aho, J. M., Dietz, A. B., Radel, D. J., Butler, G. W., Thomas, M., Nelson, T. J., Carlsen, B. T., Cassivi, S. D., Resch, Z. T., Faubion, W. A. & Wigle, D. A., Oct 1 2016, In : Stem cells translational medicine. 5, 10, p. 1375-1379 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC

Colombel, J. F., Keir, M. E., Scherl, A., Zhao, R., de Hertogh, G., Faubion, W. A. & Lu, T. T., Sep 2 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

44 Scopus citations

Efficacy and safety of escalation of adalimumab therapy to weekly dosing in pediatric patients with Crohn's disease

Dubinsky, M. C., Rosh, J., Faubion, W. A., Kierkus, J., Ruemmele, F., Hyams, J. S., Eichner, S., Li, Y., Huang, B., Mostafa, N. M., Lazar, A. & Thakkar, R. B., Mar 9 2016, In : Inflammatory Bowel Diseases. 22, 4, p. 886-893 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ

Velez, G., Lin, M., Christensen, T., Faubion, W. A., Lomberk, G. & Urrutia, R., Jan 1 2016, In : Journal of Molecular Modeling. 22, 1, p. 1-17 17 p., 12.

Research output: Contribution to journalArticle

9 Scopus citations
Open Access
17 Scopus citations
2015

A Novel Role for Kruppel-like Factor 14 (KLF14) in T-Regulatory Cell Differentiation

Sarmento, O. F., Svingen, P. A., Xiong, Y., Xavier, R. J., McGovern, D., Smyrk, T. C., Papadakis, K., Urrutia, R. A. & Faubion, W. A., Mar 1 2015, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 1, 2, p. 188-202.e4

Research output: Contribution to journalArticle

13 Scopus citations

Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort

Oliva-Hemker, M., Hutfless, S., Al Kazzi, E. S., Lerer, T., Mack, D., Leleiko, N., Griffiths, A., Cabrera, J., Otley, A., Rick, J., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Carvalho, R., Keljo, D., Pfefferkorn, M., Faubion, W. A., Kappelman, M. & 4 others, Sudel, B., Schaefer, M. E., Markowitz, J. & Hyams, J. S., Sep 1 2015, In : Journal of Pediatrics. 167, 3, p. 527-532.e3

Research output: Contribution to journalArticle

38 Scopus citations

Concomitant Use of Immunomodulators Affects the Durability of Infliximab Therapy in Children With Crohn's Disease

Grossi, V., Lerer, T., Griffiths, A., LeLeiko, N., Cabrera, J., Otley, A., Rick, J., Mack, D., Bousvaros, A., Rosh, J., Grossman, A., Saeed, S., Kay, M., Boyle, B., Oliva-Hemker, M., Keljo, D., Pfefferkorn, M., Faubion, W. A., Kappelman, M. D., Sudel, B. & 2 others, Markowitz, J. & Hyams, J. S., Oct 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 10, p. 1748-1756 9 p., 54359.

Research output: Contribution to journalArticle

41 Scopus citations
7 Scopus citations

Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation

Papadakis, K., Krempski, J., Svingen, P., Xiong, Y., Sarmento, O. F., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 11, p. G900-G909

Research output: Contribution to journalArticle

9 Scopus citations

Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes

Papadakis, K. A., Krempski, J., Reiter, J., Svingen, P., Xiong, Y., Sarmento, O. F., Huseby, A., Johnson, A. J., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., Jan 1 2015, In : American Journal of Physiology - Cell Physiology. 308, 5, p. C362-C371

Research output: Contribution to journalArticle

10 Scopus citations

Mesenchymal stem cell therapy for inflammatory bowel disease: A systematic review and meta-analysis

Dave, M., Mehta, K., Luther, J., Baruah, A., Dietz, A. B. & Faubion, W. A., Jul 25 2015, In : Inflammatory Bowel Diseases. 21, 11, p. 2696-2707 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Phenotypic characterization of mice carrying homozygous deletion of KLF11, a gene in which mutations cause human neonatal and MODY VII diabetes

Mathison, A., Escande, C., Calvo, E., Seo, S., White, T., Salmonson, A., Faubion, W. A., Buttar, N. S., Iovanna, J., Lomberk, G., Chini, E. N. & Urrutia, R., Oct 1 2015, In : Endocrinology. 156, 10, p. 3581-3595 15 p.

Research output: Contribution to journalArticle

4 Scopus citations