• 11076 Citations
  • 59 Scopus h-Index
1976 …2020

Research output per year

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Research Output

2020

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis

Peeraphatdit, T. B., Kamath, P. S., Karpyak, V. M., Davis, B., Desai, V., Liangpunsakul, S., Sanyal, A., Chalasani, N., Shah, V. H. & Simonetto, D. A., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 477-485.e5

Research output: Contribution to journalArticle

2 Scopus citations

Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives

Arab, J. P., Arrese, M. & Shah, V. H., Apr 1 2020, In : Hepatology Research. 50, 4, p. 407-418 12 p.

Research output: Contribution to journalReview article

Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12

Arab, J. P., Cabrera, D., Sehrawat, T. S., Jalan-Sakrikar, N., Verma, V. K., Simonetto, D., Cao, S., Yaqoob, U., Leon, J., Freire, M., Vargas, J. I., De Assuncao, T. M., Kwon, J. H., Guo, Y., Kostallari, E., Cai, Q., Kisseleva, T., Oh, Y., Arrese, M., Huebert, R. C. & 1 others, Shah, V. H., Jan 1 2020, (Accepted/In press) In : Journal of hepatology.

Research output: Contribution to journalArticle

Open Access

Increasing Burden of Acute-On-Chronic Liver Failure among Alcohol-Associated Liver Disease in the Young Population in the United States

Singal, A. K., Arora, S., Wong, R. J., Satapathy, S. K., Shah, V. H., Kuo, Y. F. & Kamath, P. S., Jan 1 2020, In : American Journal of Gastroenterology. 115, 1, p. 88-95 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Meeting Report: The Dallas Consensus Conference on Liver Transplantation for Alcohol Associated Hepatitis

Asrani, S. K., Trotter, J., Lake, J., Ahmed, A., Bonagura, A., Cameron, A., DiMartini, A., Gonzalez, S., Im, G., Martin, P., Mathurin, P., Mellinger, J., Rice, J. P., Shah, V. H., Terrault, N., Wall, A., Winder, S. & Klintmalm, G., Jan 1 2020, In : Liver Transplantation. 26, 1, p. 127-140 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis

Mindikoglu, A. L., Coarfa, C., Opekun, A. R., Shah, V. H., Arab, J. P., Lazaridis, K. N., Putluri, N., Ambati, C. R., Robertson, M. J., Devaraj, S., Jalal, P. K., Rana, A., Goss, J. A., Dowling, T. C., Weir, M. R., Seliger, S. L., Raufman, J. P., Bernard, D. W. & Vierling, J. M., Jan 1 2020, In : Future Science OA. 6, 2

Research output: Contribution to journalArticle

Open Access

Neutrophil Extracellular Traps and Liver Disease

Hilscher, M. B. & Shah, V. H., May 1 2020, In : Seminars in liver disease. 40, 2, p. 171-179 9 p.

Research output: Contribution to journalArticle

Outpatient management of alcohol-related liver disease

Simonetto, D. A., Shah, V. H. & Kamath, P. S., May 2020, In : The Lancet Gastroenterology and Hepatology. 5, 5, p. 485-493 9 p.

Research output: Contribution to journalReview article

Persistent Hyperactivation of Endothelial Cells in Patients with Alcoholic Hepatitis

Xia, Y., Yang, J., Sanyal, A. J., Shah, V. H., Chalasani, N. P., Yu, Q., Zheng, X. & Li, W., May 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 5, p. 1075-1087 13 p.

Research output: Contribution to journalArticle

Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis

Atkinson, S. R., Hamesch, K., Spivak, I., Guldiken, N., Cabezas, J., Argemi, J., Theurl, I., Zoller, H., Cao, S., Mathurin, P., Shah, V. H., Trautwein, C., Bataller, R., Thursz, M. R. & Strnad, P., Mar 1 2020, In : The American Journal of Gastroenterology. 115, 3, p. 398-405 8 p.

Research output: Contribution to journalArticle

Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs

Shaheen, M. F., Joo, D. J., Ross, J. J., Anderson, B. D., Chen, H. S., Huebert, R. C., Li, Y., Amiot, B., Young, A., Zlochiver, V., Nelson, E., Mounajjed, T., Dietz, A. B., Michalak, G., Steiner, B. G., Davidow, D. S., Paradise, C. R., van Wijnen, A. J., Shah, V. H., Liu, M. & 1 others, Nyberg, S. L., Apr 1 2020, In : Nature Biomedical Engineering. 4, 4, p. 437-445 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The knowns and unknowns of treatment for alcoholic hepatitis

Sehrawat, T. S., Liu, M. & Shah, V. H., May 2020, In : The Lancet Gastroenterology and Hepatology. 5, 5, p. 494-506 13 p.

Research output: Contribution to journalReview article

1 Scopus citations

The Role of Three-Dimensional Magnetic Resonance Elastography in the Diagnosis of Nonalcoholic Steatohepatitis in Obese Patients Undergoing Bariatric Surgery

Allen, A. M., Shah, V. H., Therneau, T. M., Venkatesh, S. K., Mounajjed, T., Larson, J. J., Mara, K. C., Schulte, P. J., Kellogg, T. A., Kendrick, M. L., McKenzie, T. J., Greiner, S. M., Li, J., Glaser, K. J., Wells, M. L., Chen, J., Ehman, R. L. & Yin, M., Feb 1 2020, In : Hepatology. 71, 2, p. 510-521 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study

Thursz, M., Kamath, P. S., Mathurin, P., Szabo, G. & Shah, V., Mar 1 2019, In : Journal of Hepatology. 70, 3, p. 521-530 10 p.

Research output: Contribution to journalReview article

12 Scopus citations

Alcohol-related liver disease: Clinical practice guidelines by the Latin American Association for the Study of the Liver (ALEH)

Arab, J. P., Roblero, J. P., Altamirano, J., Bessone, F., Chaves Araujo, R., Higuera-De la Tijera, F., Restrepo, J. C., Torre, A., Urzua, A., Simonetto, D., Abraldes, J. G., Méndez-Sánchez, N., Contreras, F., Lucey, M. R., Shah, V., Cortez-Pinto, H. & Bataller, R., May 1 2019, In : Annals of hepatology. 18, 3, p. 518-535 18 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study

Szabo, G., Kamath, P. S., Shah, V., Thursz, M. & Mathurin, P., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

10 Scopus citations

Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs (Nature Biomedical Engineering, (2019), 10.1038/s41551-019-0460-x)

Shaheen, M. F., Joo, D. J., Ross, J. J., Anderson, B. D., Chen, H. S., Huebert, R. C., Li, Y., Amiot, B., Young, A., Zlochiver, V., Nelson, E., Mounajjed, T., Dietz, A. B., Michalak, G., Steiner, B. G., Davidow, D. S., Paradise, C. R., van Wijnen, A. J., Shah, V. H., Liu, M. & 1 others, Nyberg, S. L., Jan 1 2019, (Accepted/In press) In : Nature Biomedical Engineering.

Research output: Contribution to journalComment/debate

Open Access
13 Scopus citations

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Argemi, J., Latasa, M. U., Atkinson, S. R., Blokhin, I. O., Massey, V., Gue, J. P., Cabezas, J., Lozano, J. J., Van Booven, D., Bell, A., Cao, S., Vernetti, L. A., Arab, J. P., Ventura-Cots, M., Edmunds, L. R., Fondevilla, C., Stärkel, P., Dubuquoy, L., Louvet, A., Odena, G. & 20 others, Gomez, J. L., Aragon, T., Altamirano, J., Caballeria, J., Jurczak, M. J., Taylor, D. L., Berasain, C., Wahlestedt, C., Monga, S. P., Morgan, M. Y., Sancho-Bru, P., Mathurin, P., Furuya, S., Lackner, C., Rusyn, I., Shah, V. H., Thursz, M. R., Mann, J., Avila, M. A. & Bataller, R., Dec 1 2019, In : Nature communications. 10, 1, 3126.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis

Martin-Mateos, R., De Assuncao, T. M., Arab, J. P., Jalan-Sakrikar, N., Yaqoob, U., Greuter, T., Verma, V. K., Mathison, A. J., Cao, S., Lomberk, G., Mathurin, P., Urrutia, R., Huebert, R. C. & Shah, V. H., 2019, In : CMGH. 7, 1, p. 197-209 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Extracellular vesicles, the liquid biopsy of the future

Eguchi, A., Kostallari, E., Feldstein, A. E. & Shah, V., Jan 1 2019, In : Journal of hepatology.

Research output: Contribution to journalComment/debate

3 Scopus citations
Open Access

Incidence and Risk Factors Associated with 30-Day Readmission for Alcoholic Hepatitis

Garg, S. K., Sarvepalli, S., Singh, D., Obaitan, I., Peeraphatdit, T., Jophlin, L., Asrani, S. K., Shah, V. H. & Leise, M. D., Nov 1 2019, In : Journal of clinical gastroenterology. 53, 10, p. 759-764 6 p.

Research output: Contribution to journalArticle

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D., Yaqoob, U., Cao, S., Revzin, A., Beyder, A., Wang, R. A., Kamath, P. S., Kubes, P. & Shah, V., Jul 1 2019, In : Gastroenterology. 157, 1, p. 193-209.e9

Research output: Contribution to journalArticle

14 Scopus citations

Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells

Wang, L., Feng, Y., Xie, X., Wu, H., Su, X. N., Qi, J., Xin, W., Gao, L., Zhang, Y., Shah, V. H. & Zhu, Q., May 2019, In : EBioMedicine. 43, p. 525-536 12 p.

Research output: Contribution to journalArticle

Open Access

New Prospects for Medical Management of Acute Alcoholic Hepatitis

Liu, M. & Shah, V., May 1 2019, In : Clinical Liver Disease. 13, 5, p. 131-135 5 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

p300 Acetyltransferase Is a Cytoplasm-to-Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor β–Stimulated Hepatic Stellate Cells

Wang, Y., Tu, K., Liu, D., Guo, L., Chen, Y., Li, Q., Maiers, J. L., Liu, Z., Shah, V. H., Dou, C., Tschumperlin, D., Voneschen, L., Yang, R. & Kang, N., Oct 1 2019, In : Hepatology. 70, 4, p. 1409-1423 15 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Pericytes in the liver

Kostallari, E. & Shah, V. H., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 153-167 15 p. (Advances in Experimental Medicine and Biology; vol. 1122).

Research output: Chapter in Book/Report/Conference proceedingChapter

Prevalence and Predictors of Third-Generation Cephalosporin Resistance in the Empirical Treatment of Spontaneous Bacterial Peritonitis

Sunjaya, D. B., Lennon, R. J., Shah, V., Kamath, P. S. & Simonetto, D., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

Abraldes, J. G., Trebicka, J., Chalasani, N., D’Amico, G., Rockey, D. C., Shah, V. H., Bosch, J. & Garcia-Tsao, G., Mar 2019, In : Hepatology. 69, 3, p. 1287-1299 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis

Jalan-Sakrikar, N., De Assuncao, T. M., Shi, G., Aseem, S. O., Chi, C., Shah, V. & Huebert, R. C., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations

Response to Forrest et al

Singal, A. K., Bataller, R., Ahn, J., Kamath, P. S. & Shah, V., Jan 1 2019, In : The American journal of gastroenterology. 114, 1, 1 p.

Research output: Contribution to journalArticle

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

Haak, A. J., Kostallari, E., Sicard, D., Ligresti, G., Choi, K. M., Caporarello, N., Jones, D. L., Tan, Q., Meridew, J., Espinosa, A. M. D., Aravamudhan, A., Maiers, J. L., Britt, R. D., Roden, A. C., Pabelick, C. M., Prakash, Y. S., Nouraie, S. M., Li, X., Zhang, Y., Kass, D. J. & 5 others, Lagares, D., Tager, A. M., Varelas, X., Shah, V. H. & Tschumperlin, D. J., Oct 30 2019, In : Science translational medicine. 11, 516, eaau6296.

Research output: Contribution to journalArticle

6 Scopus citations

Transforming growth factor (TGF) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation

Liu, Z., Li, C., Kang, N., Malhi, H., Shah, V. H. & Maiers, J. L., Mar 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3137-3151 15 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

ACG clinical guideline: Alcoholic liver disease

Singal, A. K., Bataller, R., Ahn, J., Kamath, P. S. & Shah, V., Feb 1 2018, In : American Journal of Gastroenterology. 113, 2, p. 175-194 20 p.

Research output: Contribution to journalReview article

113 Scopus citations

Alcohol-related liver disease: Time for action

Bataller, R., Arteel, G. E., Moreno, C. & Shah, V., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

4 Scopus citations

A Validated Score Predicts Acute Kidney Injury and Survival in Patients With Alcoholic Hepatitis

Sujan, R., Cruz-Lemini, M., Altamirano, J., Simonetto, D., Maiwall, R., Axley, P., Richardson, T., Desai, V., Cabezas, J., Vargas, V., Kamath, P. S., Shah, V., Sarin, S. K., Bataller, R. & Singal, A. K., Dec 1 2018, In : Liver Transplantation. 24, 12, p. 1655-1664 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Current trials and novel therapeutic targets for alcoholic hepatitis

Singal, A. K. & Shah, V., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

8 Scopus citations

Endothelial JAK2V617Fdoes not enhance liver lesions in mice with Budd-Chiari syndrome

Poisson, J., Hilscher, M. B., Tanguy, M., Hammoutene, A., Boulanger, C. M., Villeval, J. L., Simonetto, D., Valla, D., Shah, V. & Rautou, P. E., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations

Exploring new treatment paradigms for alcoholic hepatitis by extrapolating from NASH and cholestasis

Peeraphatdit, T. B., Simonetto, D. A. & Shah, V. H., Aug 2018, In : Journal of hepatology. 69, 2, p. 275-277 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Grand Rounds: Alcoholic Hepatitis

Singal, A. K., Louvet, A., Shah, V. H. & Kamath, P. S., Aug 2018, In : Journal of hepatology. 69, 2, p. 534-543 10 p.

Research output: Contribution to journalReview article

9 Scopus citations

Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Kostallari, E., Hirsova, P., Prasnicka, A., Verma, V. K., Yaqoob, U., Wongjarupong, N., Roberts, L. R. & Shah, V., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

14 Scopus citations

Hepatic stellate cells retain retinoid-laden lipid droplets after cellular transdifferentiation into activated myofibroblasts

Jophlin, L. L., Koutalos, Y., Chen, C., Shah, V. & Rockey, D. C., Nov 1 2018, In : American journal of physiology. Gastrointestinal and liver physiology. 315, 5, p. G713-G721

Research output: Contribution to journalArticle

7 Scopus citations

Isolated hepatic non-obstructive sinusoidal dilatation, 20-year single center experience

Sunjaya, D. B., Ramos, G. P., Neto, M. B. B., Lennon, R., Mounajjed, T., Shah, V., Kamath, P. S. & Simonetto, D., May 27 2018, In : World Journal of Hepatology. 10, 5, p. 417-424 8 p.

Research output: Contribution to journalArticle

Mechanosensing and fibrosis

Tschumperlin, D. J., Ligresti, G., Hilscher, M. B. & Shah, V., Jan 2 2018, In : Journal of Clinical Investigation. 128, 1, p. 74-84 11 p.

Research output: Contribution to journalReview article

45 Scopus citations

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Dou, C., Liu, Z., Tu, K., Zhang, H., Chen, C., Yaqoob, U., Wang, Y., Wen, J., Van Deursen, J., Sicard, D., Tschumperlin, D. J., Zou, H., Huang, W. C., Urrutia, R., Shah, V. & Kang, N., Jun 1 2018, In : Gastroenterology. 154, 8, p. 2209-2221.e14

Research output: Contribution to journalArticle

30 Scopus citations

PNPLA3 association with alcoholic liver disease in a cohort of heavy drinkers

Kolla, B. P., Schneekloth, T. D., Biernacka, J. M., Shah, V., Lazaridis, K. N., Geske, J. & Karpyak, V. M., Jan 1 2018, In : Alcohol and Alcoholism. 53, 4, p. 357-360 4 p.

Research output: Contribution to journalArticle

3 Scopus citations