• 10170 Citations
  • 55 Scopus h-Index
1976 …2020
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Research Output 1989 2019

2019

Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, p. e00052

Research output: Contribution to journalArticle

Open Access
Alcohol Abstinence
Alcoholic Hepatitis
HLA Antigens
Blood Cells
Mucosal-Associated Invariant T Cells

Alcohol-related liver disease: Clinical practice guidelines by the Latin American Association for the Study of the Liver (ALEH)

Arab, J. P., Roblero, J. P., Altamirano, J., Bessone, F., Chaves Araujo, R., Higuera-De la Tijera, F., Restrepo, J. C., Torre, A., Urzua, A., Simonetto, D., Abraldes, J. G., Méndez-Sánchez, N., Contreras, F., Lucey, M. R., Shah, V., Cortez-Pinto, H. & Bataller, R., May 1 2019, In : Annals of hepatology. 18, 3, p. 518-535 18 p.

Research output: Contribution to journalReview article

Open Access
Practice Guidelines
Liver Diseases
Alcohols
Liver
Alcoholic Hepatitis
5 Citations (Scopus)

Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study

Thursz, M., Kamath, P. S., Mathurin, P., Szabo, G. & Shah, V., Mar 1 2019, In : Journal of Hepatology. 70, 3, p. 521-530 10 p.

Research output: Contribution to journalReview article

Alcoholic Liver Diseases
Alcohol Drinking
Liver Diseases
Consensus
Alcohols

Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study

Szabo, G., Kamath, P. S., Shah, V., Thursz, M. & Mathurin, P., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Liver Diseases
Consensus
Alcohols
Alcoholic Liver Diseases
Alcohol Drinking
Banti's syndrome
7 Citations (Scopus)
Primary Prevention
Hemorrhage
Ligation
isosorbide-5-mononitrate
Esophageal and Gastric Varices
5 Citations (Scopus)

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis

Martin-Mateos, R., De Assuncao, T. M., Arab, J. P., Jalan-Sakrikar, N., Yaqoob, U., Greuter, T., Verma, V. K., Mathison, A. J., Cao, S., Lomberk, G., Mathurin, P., Urrutia, R., Huebert, R. C. & Shah, V., Jan 1 2019, In : CMGH. 7, 1, p. 197-209 13 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Transforming Growth Factors
Liver Cirrhosis
Platelet-Derived Growth Factor
Carbon Tetrachloride

Extracellular vesicles, the liquid biopsy of the future

Eguchi, A., Kostallari, E., Feldstein, A. E. & Shah, V., Jan 1 2019, In : Journal of hepatology.

Research output: Contribution to journalComment/debate

Biopsy
Extracellular Vesicles
Open Access
Emotional Intelligence
Gastroenterology
hexachlorocyclohexane x-factor

Incidence and Risk Factors Associated with 30-Day Readmission for Alcoholic Hepatitis

Garg, S. K., Sarvepalli, S., Singh, D., Obaitan, I., Peeraphatdit, T., Jophlin, L., Asrani, S. K., Shah, V. & Leise, M. D., Jan 1 2019, In : Journal of clinical gastroenterology.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Incidence
Patient Readmission
Skilled Nursing Facilities
Alcoholic Liver Cirrhosis
2 Citations (Scopus)

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D., Yaqoob, U., Cao, S., Revzin, A., Beyder, A., Wang, R. A., Kamath, P. S., Kubes, P. & Shah, V., Jul 1 2019, In : Gastroenterology. 157, 1, p. 193-209.e9

Research output: Contribution to journalArticle

Portal Hypertension
Neutrophils
Endothelial Cells
Liver
RNA Sequence Analysis

Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells

Wang, L., Feng, Y., Xie, X., Wu, H., Su, X. N., Qi, J., Xin, W., Gao, L., Zhang, Y., Shah, V. & Zhu, Q., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journalArticle

Open Access
Neuropilin-1
Endothelial cells
Phosphatidylinositol 3-Kinases
Liver Cirrhosis
Liver

New Prospects for Medical Management of Acute Alcoholic Hepatitis

Liu, M. & Shah, V., May 1 2019, In : Clinical Liver Disease. 13, 5, p. 131-135 5 p.

Research output: Contribution to journalReview article

Open Access
Alcoholic Hepatitis

Pericytes in the liver

Kostallari, E. & Shah, V., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 153-167 15 p. (Advances in Experimental Medicine and Biology; vol. 1122).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hepatic Stellate Cells
Pericytes
Liver
Liver Diseases
Endothelial cells

Prevalence and Predictors of Third-Generation Cephalosporin Resistance in the Empirical Treatment of Spontaneous Bacterial Peritonitis

Sunjaya, D. B., Lennon, R. J., Shah, V., Kamath, P. S. & Simonetto, D., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Cephalosporin Resistance
Peritonitis
Cephalosporins
Microbial Drug Resistance
Drug Resistance
1 Citation (Scopus)

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

Abraldes, J. G., Trebicka, J., Chalasani, N., D’Amico, G., Rockey, D. C., Shah, V., Bosch, J. & Garcia-Tsao, G., Mar 1 2019, In : Hepatology. 69, 3, p. 1287-1299 13 p.

Research output: Contribution to journalArticle

Portal Hypertension
Portal Pressure
Fibrosis
Therapeutics
Industry

Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis

Jalan-Sakrikar, N., De Assuncao, T. M., Shi, G., Aseem, S. O., Chi, C., Shah, V. & Huebert, R. C., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

Transforming Growth Factors
Fibrosis
Fibronectins
Hepatic Stellate Cells
Ubiquitin

Response to Forrest et al

Singal, A. K., Bataller, R., Ahn, J., Kamath, P. S. & Shah, V., Jan 1 2019, In : The American journal of gastroenterology. 114, 1, 1 p.

Research output: Contribution to journalArticle

The Role of Three-Dimensional Magnetic Resonance Elastography in the Diagnosis of Nonalcoholic Steatohepatitis in Obese Patients Undergoing Bariatric Surgery

Allen, A., Shah, V., Therneau, T. M., Venkatesh, S. K., Mounajjed, T., Larson, J. J., Mara, K. C., Schulte, P., Kellogg, T. A., Kendrick, M. L., McKenzie, T. J., Greiner, S. M., Li, J., Glaser, K. J., Wells, M., Chen, J., Ehman, R. L. & Yin, M., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Bariatric Surgery
Fats
Protons
Magnetic Resonance Imaging
1 Citation (Scopus)

Transforming growth factor (TGF) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation

Liu, Z., Li, C., Kang, N., Malhi, H. M., Shah, V. & Maiers, J., Jan 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3137-3151 15 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Hepatic Stellate Cells
Transforming Growth Factors
Chemical activation
CCAAT-Enhancer-Binding Proteins
2018
59 Citations (Scopus)

ACG clinical guideline: Alcoholic liver disease

Singal, A. K., Bataller, R., Ahn, J., Kamath, P. S. & Shah, V., Feb 1 2018, In : American Journal of Gastroenterology. 113, 2, p. 175-194 20 p.

Research output: Contribution to journalReview article

Alcoholic Liver Diseases
Alcoholic Hepatitis
Guidelines
Liver Diseases
Alcoholic Liver Cirrhosis
1 Citation (Scopus)

Alcohol-related liver disease: Time for action

Bataller, R., Arteel, G. E., Moreno, C. & Shah, V., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Liver Diseases
Alcohols
3 Citations (Scopus)

A Validated Score Predicts Acute Kidney Injury and Survival in Patients With Alcoholic Hepatitis

Sujan, R., Cruz-Lemini, M., Altamirano, J., Simonetto, D., Maiwall, R., Axley, P., Richardson, T., Desai, V., Cabezas, J., Vargas, V., Kamath, P. S., Shah, V., Sarin, S. K., Bataller, R. & Singal, A. K., Dec 1 2018, In : Liver Transplantation. 24, 12, p. 1655-1664 10 p.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Acute Kidney Injury
Survival
Inpatients
Systemic Inflammatory Response Syndrome
2 Citations (Scopus)

Current trials and novel therapeutic targets for alcoholic hepatitis

Singal, A. K. & Shah, V., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Clinical Trials
Therapeutics
Liver Transplantation
Oxidative Stress
1 Citation (Scopus)

Endothelial JAK2V617Fdoes not enhance liver lesions in mice with Budd-Chiari syndrome

Poisson, J., Hilscher, M. B., Tanguy, M., Hammoutene, A., Boulanger, C. M., Villeval, J. L., Simonetto, D., Valla, D., Shah, V. & Rautou, P. E., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Budd-Chiari Syndrome
Portal Hypertension
Liver Cirrhosis
Liver
1 Citation (Scopus)

Exploring new treatment paradigms for alcoholic hepatitis by extrapolating from NASH and cholestasis

Peeraphatdit, T. B., Simonetto, D. & Shah, V., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Cholestasis
6 Citations (Scopus)

Grand Rounds: Alcoholic Hepatitis

Singal, A. K., Louvet, A., Shah, V. & Kamath, P. S., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Teaching Rounds
Alcoholic Hepatitis
Alcohols
Jaundice
Bilirubin
9 Citations (Scopus)

Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Kostallari, E., Hirsova, P., Prasnicka, A., Verma, V. K., Yaqoob, U., Wongjarupong, N., Roberts, L. R. & Shah, V., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor alpha Receptor
Hepatic Stellate Cells
Liver Cirrhosis
src Homology Domains
Phosphoric Monoester Hydrolases
2 Citations (Scopus)

Hepatic stellate cells retain retinoid-laden lipid droplets after cellular transdifferentiation into activated myofibroblasts

Jophlin, L. L., Koutalos, Y., Chen, C., Shah, V. & Rockey, D. C., Nov 1 2018, In : American journal of physiology. Gastrointestinal and liver physiology. 315, 5, p. G713-G721

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Myofibroblasts
Retinoids
Esters
Cell Transdifferentiation

Isolated hepatic non-obstructive sinusoidal dilatation, 20-year single center experience

Sunjaya, D. B., Ramos, G. P., Neto, M. B. B., Lennon, R., Mounajjed, T., Shah, V., Kamath, P. S. & Simonetto, D., May 27 2018, In : World Journal of Hepatology. 10, 5, p. 417-424 8 p.

Research output: Contribution to journalArticle

Dilatation
Liver
Portal Hypertension
Atrophy
Purpura
26 Citations (Scopus)

Mechanosensing and fibrosis

Tschumperlin, D. J., Ligresti, G., Hilscher, M. B. & Shah, V., Jan 2 2018, In : Journal of Clinical Investigation. 128, 1, p. 74-84 11 p.

Research output: Contribution to journalReview article

Fibrosis
Wounds and Injuries
Homeostasis
Epigenomics
17 Citations (Scopus)

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Dou, C., Liu, Z., Tu, K., Zhang, H., Chen, C., Yaqoob, U., Wang, Y., Wen, J., Van Deursen, J., Sicard, D., Tschumperlin, D. J., Zou, H., Huang, W. C., Urrutia, R., Shah, V. & Kang, N., Jun 1 2018, In : Gastroenterology. 154, 8, p. 2209-2221.e14

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Myofibroblasts
Neoplasms
Liver
Neoplasm Metastasis
2 Citations (Scopus)

PNPLA3 association with alcoholic liver disease in a cohort of heavy drinkers

Kolla, B. P., Schneekloth, T. D., Biernacka, J. M., Shah, V., Lazaridis, K. N., Geske, J. & Karpyak, V. M., Jan 1 2018, In : Alcohol and Alcoholism. 53, 4, p. 357-360 4 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Liver
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
1 Citation (Scopus)

Posttraumatic Stress Disorder in Patients with Heavy Alcohol Consumption and Alcoholic Hepatitis

Samala, N., Lourens, S. G., Shah, V., Kamath, P. S., Sanyal, A. J., Crabb, D. W., Tang, Q., Radaeva, S., Liangpunsakul, S. & Chalasani, N., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Post-Traumatic Stress Disorders
Alcohol Drinking
Alcohols
Liver
15 Citations (Scopus)

The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis

Puri, P., Liangpunsakul, S., Christensen, J. E., Shah, V., Kamath, P. S., Gores, G. J., Walker, S., Comerford, M., Katz, B., Borst, A., Yu, Q., Kumar, D. P., Mirshahi, F., Radaeva, S., Chalasani, N. P., Crabb, D. W. & Sanyal, A. J., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Metagenomics
Microbiota
Drinking
Fusobacteria

Too Stiff, Too Late.. Timing Is Everything in Antiangiogenic Treatment of Liver Fibrosis

Greuter, T. & Shah, V., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Liver Cirrhosis

Viral Hepatitis: Knowledge and Treatments for Hepatitis B and C Virus and Associated Transplantation and Neoplasia

Sherman, K. E. & Shah, V., Feb 1 2018, In : Gastroenterology. 154, 3, p. 453-456 4 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepacivirus
Hepatitis
Transplantation
Neoplasms
2017
5 Citations (Scopus)

Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study

Li, W., Amet, T., Xing, Y., Yang, D., Liangpunsakul, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V., Katz, B. P., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Aug 1 2017, In : Hepatology. 66, 2, p. 575-590 16 p.

Research output: Contribution to journalArticle

Alcohol Abstinence
Alcoholic Hepatitis
Observational Studies
Prospective Studies
Chemokine CCL22

Alcoholic hepatitis: Continued drinking and the mourning after

Simonetto, D., Kamath, P. S. & Shah, V., Nov 1 2017, In : Hepatology. 66, 5, p. 1370-1372 3 p.

Research output: Contribution to journalEditorial

Alcoholic Hepatitis
Alcoholic Liver Cirrhosis
Grief
Alcohol Drinking
Drinking
2 Citations (Scopus)

An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis

Beaudoin, J. J., Long, N., Liangpunsakul, S., Puri, P., Kamath, P. S., Shah, V., Sanyal, A. J., Crabb, D. W., Chalasani, N. P. & Urban, T. J., Aug 3 2017, (Accepted/In press) In : Scandinavian Journal of Gastroenterology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Genome
Genome-Wide Association Study
Genes
Alcoholic Liver Cirrhosis
1 Citation (Scopus)

Beta-blockers in patients with advanced cirrhosis: Red light, green light, yellow light…

Peeraphatdit, T. B., Kamath, P. S. & Shah, V., Jun 1 2017, In : Liver Transplantation. 23, 6, p. 725-726 2 p.

Research output: Contribution to journalEditorial

Methyl Green
Fibrosis
Light

Challenges in Patient Enrollment and Retention in Clinical Studies for Alcoholic Hepatitis: Experience of the TREAT Consortium

Comerford, M., Lourens, S., Liangpunsakul, S., Chalasani, N. P., Sanyal, A. J., Shah, V., Kamath, P. S., Puri, P., Katz, B. P., Radaeva, S. & Crabb, D. W., 2017, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Screening
Observational Studies
Refusal to Participate
Demography
33 Citations (Scopus)

Distinguishing between hepatic inflammation and fibrosis with MR elastography

Yin, M., Glaser, K. J., Manduca, A., Mounajjed, T., Malhi, H. M., Simonetto, D., Wang, R., Yang, L., Mao, S. A., Glorioso, J. M., Elgilani, F. M., Ward, C. J., Harris, P. C., Nyberg, S., Shah, V. & Ehman, R. L., Sep 1 2017, In : Radiology. 284, 3, p. 694-705 12 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Fibrosis
Inflammation
Liver
Portal Hypertension
14 Citations (Scopus)

Gut–liver axis, cirrhosis and portal hypertension: the chicken and the egg

Arab, J. P., Martin-Mateos, R. M. & Shah, V., May 26 2017, (Accepted/In press) In : Hepatology International. p. 1-10 10 p.

Research output: Contribution to journalArticle

Portal Hypertension
Ovum
Chickens
Fibrosis
Liver Diseases
1 Citation (Scopus)

Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate–Induced Cell Migration

Wang, R., Ding, Q., De Assuncao, T. M., Mounajjed, T., Maiers, J., Dou, C., Cao, S., Yaqoob, U., Huebert, R. C. & Shah, V., Jan 1 2017, In : American Journal of Pathology. 187, 1, p. 134-145 12 p.

Research output: Contribution to journalArticle

Dynamin II
Hepatic Stellate Cells
Sphingosine
GTP Phosphohydrolases
Cell Movement

Improving survival in ACLF: growing evidence for use of G-CSF

Simonetto, D., Shah, V. & Kamath, P. S., Nov 9 2017, (Accepted/In press) In : Hepatology International. p. 1-3 3 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
7 Citations (Scopus)

Infection in Severe Alcoholic Hepatitis: Yet Another Piece in the Puzzle

Singal, A. K., Shah, V. & Kamath, P. S., Apr 1 2017, In : Gastroenterology. 152, 5, p. 938-940 3 p.

Research output: Contribution to journalEditorial

Alcoholic Hepatitis
Infection
16 Citations (Scopus)
Liver
Macrophages
Inflammation
Chemotaxis
Myeloid Cells
5 Citations (Scopus)

Lipopolysaccharide downregulates macrophage-derived IL-22 to modulate alcohol-induced hepatocyte cell death

Liu, Y., Verma, V. K., Malhi, H. M., Gores, G. J., Kamath, P. S., Sanyal, A., Chalasani, N., Gao, B. & Shah, V., Sep 5 2017, In : American Journal of Physiology - Cell Physiology. 313, 3, p. C305-C313

Research output: Contribution to journalArticle

Lipopolysaccharides
Hepatocytes
Cell Death
Down-Regulation
Macrophages

Reply to ''Alcohol and Liver Transplantation''

Russ, K. B., Chen, N. W., Kamath, P. S., Shah, V., Kuo, Y. F. & Singal, A. K., Jan 1 2017, In : Alcohol and alcoholism (Oxford, Oxfordshire). 52, 1, p. 127 1 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Alcohol Drinking
Liver Transplantation
Alcoholism
Alcohols