Verline Justilien, PhD

  • 1164 Citations
  • 17 Scopus h-Index
20072020

Research output per year

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Research Output

  • 1164 Citations
  • 17 Scopus h-Index
  • 22 Article
  • 3 Comment/debate
  • 1 Short survey
  • 1 Review article
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Article

Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma

Liu, Y., Yin, N., Wang, X., Khoor, A., Sambandam, V., Ghosh, A. B., Fields, Z. A., Murray, N. R., Justilien, V. & Fields, A. P., Jan 21 2020, In : Cell reports. 30, 3, p. 771-782.e6

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Ect2-Dependent rRNA Synthesis Is Required for KRAS-TRP53-Driven Lung Adenocarcinoma

Justilien, V., Ali, S. A., Jamieson, L., Yin, N., Cox, A. D., Der, C. J., Murray, N. R. & Fields, A. P., Feb 13 2017, In : Cancer cell. 31, 2, p. 256-269 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Ect2 links the PKC-Par6α complex to Rac1 activation and cellular transformation

Justilien, V. & Fields, A. P., Oct 15 2009, In : Oncogene. 28, 41, p. 3597-3607 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Matrix metalloproteinase-10 is a critical effector of protein kinase Cι-Par6α-mediated lung cancer

Frederick, L. A., Matthews, J. A., Jamieson, L., Justilien, V., Thompson, E. A., Radisky, D. C. & Fields, A. P., Aug 14 2008, In : Oncogene. 27, 35, p. 4841-4853 13 p.

Research output: Contribution to journalArticle

67 Scopus citations

Matrix metalloproteinase-10 is required for lung cancer stem cell maintenance, tumor initiation and metastatic potential

Justilien, V., Regala, R. P., Tseng, I. C., Walsh, M. P., Batra, J., Radisky, E. S., Murray, N. R. & Fields, A. P., Apr 24 2012, In : PloS one. 7, 4, e35040.

Research output: Contribution to journalArticle

62 Scopus citations

Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation

Regala, R. P., Justilien, V., Walsh, M. P., Weems, C., Khoor, A., Murray, N. R. & Fields, A. P., Oct 17 2011, In : PloS one. 6, 10, e26439.

Research output: Contribution to journalArticle

24 Scopus citations

Oncogenic activity of Ect2 is regulated through protein kinase Cι-mediated phosphorylation

Justilien, V., Jameison, L., Der, C. J., Rossman, K. L. & Fields, A. P., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8149-8157 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Oncogenic Ect2 signaling regulates rRNA synthesis in NSCLC

Justilien, V., Lewis, K. C., Murray, N. R. & Fields, A. P., Sep 3 2019, In : Small GTPases. 10, 5, p. 388-394 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis

Wang, Y., Justilien, V., Brennan, K. I., Jamieson, L., Murray, N. R. & Fields, A. P., Jan 26 2017, In : Oncogene. 36, 4, p. 534-545 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme

Gorbatyuk, M., Justilien, V., Liu, J., Hauswirth, W. W. & Lewin, A. S., Jan 2007, In : Experimental Eye Research. 84, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)

O'Neill, A. K., Gallegos, L. L., Justilien, V., Garcia, E. L., Leitges, M., Fields, A. P., Hall, R. A. & Newton, A. C., Dec 16 2011, In : Journal of Biological Chemistry. 286, 50, p. 43559-43568 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma

Yin, N., Liu, Y., Khoor, A., Wang, X., Thompson, E. A., Leitges, M., Justilien, V., Weems, C., Murray, N. R. & Fields, A. P., Aug 12 2019, In : Cancer cell. 36, 2, p. 156-167.e7

Research output: Contribution to journalArticle

4 Scopus citations

Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma

Ali, S. A., Justilien, V., Jamieson, L., Murray, N. R. & Fields, A. P., Mar 14 2016, In : Cancer cell. 29, 3, p. 367-378 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells

Justilien, V., Lewis, K. C., Meneses, K. M., Jamieson, L., Murray, N. R. & Fields, A. P., Jun 12 2020, In : The Journal of biological chemistry. 295, 24, p. 8214-8226 13 p.

Research output: Contribution to journalArticle

Role of transcription regulatory complexes and epigenetic modifications in driving the cell fate decisions

Ali, S. A., Justilien, V., Bukhari, S. Z. H., Lee, J. & Shakoori, A. R., Jan 1 2015, In : Pakistan Journal of Zoology. 47, 1, p. 287-293 7 p.

Research output: Contribution to journalArticle

SOD2 knockdown mouse model of early AMD

Justilien, V., Pang, J. J., Renganathan, K., Zhan, X., Crabb, J. W., So, R. K., Sparrow, J. R., Hauswirth, W. W. & Lewin, A. S., Oct 2007, In : Investigative Ophthalmology and Visual Science. 48, 10, p. 4407-4420 14 p.

Research output: Contribution to journalArticle

164 Scopus citations

Suppression of mouse rhodopsin expression in vivo by AAV mediated siRNA delivery

Gorbatyuk, M., Justilien, V., Liu, J., Hauswirth, W. W. & Lewin, A. S., Apr 2007, In : Vision Research. 47, 9, p. 1202-1208 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Targeting oncogenic protein kinase Cι for treatment of mutant KRAS LADC

Fields, A. P., Ali, S. A., Justilien, V. & Murray, N. R., Jan 2 2017, In : Small GTPases. 8, 1, p. 58-64 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

The chromosome 3q26 OncCassette: A multigenic driver of human cancer

Fields, A. P., Justilien, V. & Murray, N. R., Jan 1 2016, In : Advances in Biological Regulation. 60, p. 47-63 17 p.

Research output: Contribution to journalArticle

33 Scopus citations

The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer

Fields, A. P. & Justilien, V., 2010, In : Advances in Enzyme Regulation. 50, 1, p. 190-200 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma

Justilien, V., Walsh, M. P., Ali, S. A., Thompson, E. A., Murray, N. R. & Fields, A. P., Feb 10 2014, In : Cancer cell. 25, 2, p. 139-151 13 p.

Research output: Contribution to journalArticle

176 Scopus citations
8 Scopus citations