Timothy Kline, PhD

  • 992 Citations
  • 17 Scopus h-Index
20092020

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Research Output

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Accuracy of microvascular measurements obtained from micro-CT images

Kline, T. L., Zamir, M. & Ritman, E. L., Sep 2010, In : Annals of Biomedical Engineering. 38, 9, p. 2851-2864 14 p.

Research output: Contribution to journalArticle

26 Scopus citations

Algorithm-enabled low-dose micro-CT imaging

Han, X., Bian, J., Eaker, D. R., Kline, T. L., Sidky, E. Y., Ritman, E. L. & Pan, X., Mar 1 2011, In : IEEE transactions on medical imaging. 30, 3, p. 606-620 15 p., 5609203.

Research output: Contribution to journalArticle

113 Scopus citations

Anatomy of hepatic arteriolo-portal venular shunts evaluated by 3D micro-CT imaging

Kline, T. L., Knudsen, B. E., Anderson, J. L., Vercnocke, A. J., Jorgensen, S. M. & Ritman, E. L., Jun 2014, In : Journal of Anatomy. 224, 6, p. 724-731 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Automated Abdominal Segmentation of CT Scans for Body Composition Analysis Using Deep Learning

Weston, A. D., Korfiatis, P., Kline, T. L., Philbrick, K. A., Kostandy, P., Sakinis, T., Sugimoto, M., Takahashi, N. & Erickson, B. J., Mar 1 2019, In : Radiology. 290, 3, p. 669-679 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Automatic measurement of kidney and liver volumes from MR images of patients affected by autosomal dominant polycystic kidney disease

van Gastel, M. D. A., Edwards, M. E., Torres, V. E., Erickson, B. J., Gansevoort, R. T. & Kline, T. L., Aug 2019, In : Journal of the American Society of Nephrology. 30, 8, p. 1514-1522 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
29 Scopus citations

Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression

Raina, R., Chakraborty, R., DeCoy, M. E. & Kline, T., Jan 1 2020, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Kline, T. L., Xu, Y. H., Jing, Y. & Wang, J. P., May 1 2009, In : Journal of Magnetism and Magnetic Materials. 321, 10, p. 1525-1528 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Characterization of the pore labyrinth geometry of sea sponges imaged by micro-CT

Kline, T. L. & Ritman, E. L., Apr 2012, In : Journal of Porous Materials. 19, 2, p. 141-151 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Coronary microcirculation changes in non-ischemic dilated cardiomyopathy identified by novel perfusion CT

Miller, W. L., Behrenbeck, T. R., McCollough, C. H., Williamson, E. E., Leng, S., Kline, T. & Ritman, E. L., Feb 25 2015, (Accepted/In press) In : International Journal of Cardiovascular Imaging.

Research output: Contribution to journalArticle

5 Scopus citations

Deep Learning in Radiology: Does One Size Fit All?

Erickson, B. J., Korfiatis, P., Kline, T. L., Akkus, Z., Philbrick, K. & Weston, A. D., Mar 2018, In : Journal of the American College of Radiology. 15, 3, p. 521-526 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Early changes in myocardial microcirculation in asymptomatic hypercholesterolemic subjects: As detected by perfusion CT

Behrenbeck, T. R., McCollough, C. H., Miller, W. L., Williamson, E. E., Leng, S., Kline, T. L. & Ritman, E. L., 2014, In : Annals of Biomedical Engineering. 42, 3, p. 515-525 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia

Jing, Y., Sohn, H., Kline, T., Victora, R. H. & Wang, J. P., Apr 27 2009, In : Journal of Applied Physics. 105, 7, 07B305.

Research output: Contribution to journalArticle

16 Scopus citations

Image texture features predict renal function decline in patients with autosomal dominant polycystic kidney disease

CRISP Investigators, Nov 2017, In : Kidney international. 92, 5, p. 1206-1216 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Influence of water based embedding media composition on the relaxation properties of fixed tissue

Vučković, I., Nayfeh, T., Mishra, P. K., Periyanan, S., Sussman, C. R., Kline, T. L. & Macura, S., Apr 2020, In : Magnetic Resonance Imaging. 67, p. 7-17 11 p.

Research output: Contribution to journalArticle

Kidney and cystic volume imaging for disease presentation and progression in the cat autosomal dominant polycystic kidney disease large animal model

Yu, Y., Shumway, K. L., Matheson, J. S., Edwards, M. E., Kline, T. L. & Lyons, L. A., Jul 12 2019, In : BMC Nephrology. 20, 1, 259.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Long-term administration of tolvaptan in autosomal dominant polycystic kidney disease

Edwards, M. E., Chebib, F., Irazabal Mira, M., Ofstie, T. G., Bungum, L. A., Metzger, A. J., Senum, S. R., Hogan, M. C., El-Zoghby, Z. M., Kline, T., Harris, P. C., Czerwiec, F. S. & Torres, V., Aug 7 2018, In : Clinical Journal of the American Society of Nephrology. 13, 8, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Machine learning for medical imaging

Erickson, B. J., Korfiatis, P., Akkus, Z. & Kline, T., Mar 1 2017, In : Radiographics. 37, 2, p. 505-515 11 p.

Research output: Contribution to journalArticle

238 Scopus citations

MIRMAID: A content management system for medical image analysis research

Korfiatis, P., Kline, T., Blezek, D. J., Langer, S. G., Ryan, W. J. & Erickson, B. J., Sep 1 2015, In : Radiographics. 35, 5, p. 1461-1468 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
59 Scopus citations

Noninvasive assessment of renal fibrosis with magnetization transfer MR imaging: Validation and evaluation in murine renal artery stenosis

Jiang, K., Ferguson, C. M., Ebrahimi, B., Tang, H., Kline, T., Burningham, T. A., Mishra, P. K., Grande, J. P., Macura, S. I. & Lerman, L. O., Apr 1 2017, In : Radiology. 283, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Performance of an Artificial Multi-observer Deep Neural Network for Fully Automated Segmentation of Polycystic Kidneys

Kline, T. L., Korfiatis, P., Edwards, M. E., Blais, J. D., Czerwiec, F. S., Harris, P. C., King, B. F., Torres, V. E. & Erickson, B. J., Aug 1 2017, In : Journal of Digital Imaging. 30, 4, p. 442-448 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Quantitative MRI of kidneys in renal disease

Kline, T., Edwards, M. E., Garg, I., Irazabal Mira, M., Korfiatis, P., Harris, P. C., King, B. F., Torres, V., Venkatesh, S. K. & Erickson, B. J., Jun 28 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD)

Wong, A. T. Y., Mannix, C., Grantham, J. J., Allman-Farinelli, M., Badve, S. V., Boudville, N., Byth, K., Chan, J., Coulshed, S., Edwards, M. E., Erickson, B. J., Fernando, M., Foster, S., Haloob, I., Harris, D. C. H., Hawley, C. M., Hill, J., Howard, K., Howell, M., Jiang, S. H. & 14 others, Johnson, D. W., Kline, T. L., Kumar, K., Lee, V. W., Lonergan, M., Mai, J., McCloud, P., Peduto, A., Rangan, A., Roger, S. D., Sud, K., Torres, V., Vliayuri, E. & Rangan, G. K., Jan 1 2018, In : BMJ open. 8, 1, e018794.

Research output: Contribution to journalArticle

19 Scopus citations

Relating function to branching geometry: A micro-CT study of the hepatic artery, portal vein, and biliary tree

Kline, T. L., Zamir, M. & Ritman, E. L., Oct 1 2011, In : Cells Tissues Organs. 194, 5, p. 431-442 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
40 Scopus citations

RIL-Contour: a Medical Imaging Dataset Annotation Tool for and with Deep Learning

Philbrick, K. A., Weston, A. D., Akkus, Z., Kline, T. L., Korfiatis, P., Sakinis, T., Kostandy, P., Boonrod, A., Zeinoddini, A., Takahashi, N. & Erickson, B. J., Aug 15 2019, In : Journal of Digital Imaging. 32, 4, p. 571-581 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Semiautomated segmentation of polycystic kidneys in T2-weighted MR images

Kline, T., Edwards, M. E., Korfiatis, P., Akkus, Z., Torres, V. & Erickson, B. J., Sep 1 2016, In : American Journal of Roentgenology. 207, 3, p. 605-613 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Semi-automated segmentation of pre-operative low grade gliomas in magnetic resonance imaging

Akkus, Z., Sedlar, J., Coufalova, L., Korfiatis, P., Kline, T. L., Warner, J. D., Agrawal, J. & Erickson, B. J., Aug 14 2015, In : Cancer Imaging. 15, 1, 12.

Research output: Contribution to journalArticle

11 Scopus citations

Standardizing total kidney volume measurements for clinical trials of autosomal dominant polycystic kidney disease

Edwards, M. E., Blais, J. D., Czerwiec, F. S., Erickson, B. J., Torres, V. E. & Kline, T. L., 2019, In : Clinical Kidney Journal. 12, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

SU‐E‐I‐40: Reconstruction of Sparse Images from Few‐View Cone‐Beam Data

Han, X., Bian, J., Eaker, D., Kline, T., Sidky, E., Ritman, E. & Pan, X., Jan 1 2011, In : Medical Physics. 38, 6, p. 3404-3405 2 p.

Research output: Contribution to journalArticle

Synchrotron-based micro-CT imaging of the human lung acinus

Litzlbauer, H. D., Korbel, K., Kline, T. L., Jorgensen, S. M., Eaker, D. R., Bohle, R. M., Ritman, E. L. & Langheinrich, A. C., Sep 2010, In : Anatomical Record. 293, 9, p. 1607-1614 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Thermal response of superparamagnetic particles suspended in liquid and solid media

Zeng, P., Kline, T. L., Wang, J. P. & Wiedmann, T. S., Mar 1 2009, In : Journal of Magnetism and Magnetic Materials. 321, 5, p. 373-376 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Three-dimensional NMR microscopy of zebrafish specimens

Kline, T. L., Sussman, C. R., Irazabal, M. V., Mishra, P. K., Pearson, E. A., Torres, V. E. & Macura, S. I., Jan 2019, In : NMR in Biomedicine. 32, 1, e4031.

Research output: Contribution to journalArticle

2 Scopus citations
21 Scopus citations

What does deep learning see? Insights from a classifier trained to predict contrast enhancement phase from CT images

Philbrick, K. A., Yoshida, K., Inoue, D., Akkus, Z., Kline, T. L., Weston, A. D., Korfiatis, P., Takahashi, N. & Erickson, B. J., Dec 2018, In : American Journal of Roentgenology. 211, 6, p. 1184-1193 10 p.

Research output: Contribution to journalArticle

12 Scopus citations