Timothy Kline, PhD

  • 957 Citations
  • 16 Scopus h-Index
20092020

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2020

Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression

Raina, R., Chakraborty, R., DeCoy, M. E. & Kline, T., Jan 1 2020, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Influence of water based embedding media composition on the relaxation properties of fixed tissue

Vučković, I., Nayfeh, T., Mishra, P. K., Periyanan, S., Sussman, C. R., Kline, T. L. & Macura, S., Apr 2020, In : Magnetic Resonance Imaging. 67, p. 7-17 11 p.

Research output: Contribution to journalArticle

2019

Automated Abdominal Segmentation of CT Scans for Body Composition Analysis Using Deep Learning

Weston, A. D., Korfiatis, P., Kline, T. L., Philbrick, K. A., Kostandy, P., Sakinis, T., Sugimoto, M., Takahashi, N. & Erickson, B. J., Mar 1 2019, In : Radiology. 290, 3, p. 669-679 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Automatic Measurement of Kidney and Liver Volumes from MR Images of Patients Affected by Autosomal Dominant Polycystic Kidney Disease

van Gastel, M. D. A., Edwards, M. E., Torres, V., Erickson, B. J., Gansevoort, R. T. & Kline, T., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1514-1522 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Kidney and cystic volume imaging for disease presentation and progression in the cat autosomal dominant polycystic kidney disease large animal model

Yu, Y., Shumway, K. L., Matheson, J. S., Edwards, M. E., Kline, T. L. & Lyons, L. A., Jul 12 2019, In : BMC Nephrology. 20, 1, 259.

Research output: Contribution to journalArticle

Open Access

RIL-Contour: a Medical Imaging Dataset Annotation Tool for and with Deep Learning

Philbrick, K. A., Weston, A. D., Akkus, Z., Kline, T., Korfiatis, P., Sakinis, T., Kostandy, P., Boonrod, A., Zeinoddini, A., Takahashi, N. M. & Erickson, B. J., Jan 1 2019, In : Journal of Digital Imaging.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Standardizing total kidney volume measurements for clinical trials of autosomal dominant polycystic kidney disease

Edwards, M. E., Blais, J. D., Czerwiec, F. S., Erickson, B. J., Torres, V. & Kline, T., Jan 1 2019, In : Clinical Kidney Journal. 12, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Three-dimensional NMR microscopy of zebrafish specimens

Kline, T. L., Sussman, C. R., Irazabal, M. V., Mishra, P. K., Pearson, E. A., Torres, V. E. & Macura, S. I., Jan 2019, In : NMR in Biomedicine. 32, 1, e4031.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Deep Learning in Radiology: Does One Size Fit All?

Erickson, B. J., Korfiatis, P., Kline, T., Akkus, Z., Philbrick, K. & Weston, A. D., Jan 1 2018, (Accepted/In press) In : Journal of the American College of Radiology.

Research output: Contribution to journalArticle

30 Scopus citations

Long-term administration of tolvaptan in autosomal dominant polycystic kidney disease

Edwards, M. E., Chebib, F., Irazabal Mira, M., Ofstie, T. G., Bungum, L. A., Metzger, A. J., Senum, S. R., Hogan, M. C., El-Zoghby, Z. M., Kline, T., Harris, P. C., Czerwiec, F. S. & Torres, V., Aug 7 2018, In : Clinical Journal of the American Society of Nephrology. 13, 8, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD)

Wong, A. T. Y., Mannix, C., Grantham, J. J., Allman-Farinelli, M., Badve, S. V., Boudville, N., Byth, K., Chan, J., Coulshed, S., Edwards, M. E., Erickson, B. J., Fernando, M., Foster, S., Haloob, I., Harris, D. C. H., Hawley, C. M., Hill, J., Howard, K., Howell, M., Jiang, S. H. & 14 others, Johnson, D. W., Kline, T. L., Kumar, K., Lee, V. W., Lonergan, M., Mai, J., McCloud, P., Peduto, A., Rangan, A., Roger, S. D., Sud, K., Torres, V., Vliayuri, E. & Rangan, G. K., Jan 1 2018, In : BMJ open. 8, 1, e018794.

Research output: Contribution to journalArticle

16 Scopus citations

What does deep learning see? Insights from a classifier trained to predict contrast enhancement phase from CT images

Philbrick, K. A., Yoshida, K., Inoue, D., Akkus, Z., Kline, T., Weston, A. D., Korfiatis, P., Takahashi, N. M. & Erickson, B. J., Dec 1 2018, In : American Journal of Roentgenology. 211, 6, p. 1184-1193 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Machine learning for medical imaging

Erickson, B. J., Korfiatis, P., Akkus, Z. & Kline, T., Mar 1 2017, In : Radiographics. 37, 2, p. 505-515 11 p.

Research output: Contribution to journalArticle

224 Scopus citations

Noninvasive assessment of renal fibrosis with magnetization transfer MR imaging: Validation and evaluation in murine renal artery stenosis

Jiang, K., Ferguson, C. M., Ebrahimi, B., Tang, H., Kline, T., Burningham, T. A., Mishra, P. K., Grande, J. P., Macura, S. I. & Lerman, L. O., Apr 1 2017, In : Radiology. 283, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Performance of an Artificial Multi-observer Deep Neural Network for Fully Automated Segmentation of Polycystic Kidneys

Kline, T. L., Korfiatis, P., Edwards, M. E., Blais, J. D., Czerwiec, F. S., Harris, P. C., King, B. F., Torres, V. E. & Erickson, B. J., Aug 1 2017, In : Journal of Digital Imaging. 30, 4, p. 442-448 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Quantitative MRI of kidneys in renal disease

Kline, T., Edwards, M. E., Garg, I., Irazabal Mira, M., Korfiatis, P., Harris, P. C., King, B. F., Torres, V., Venkatesh, S. K. & Erickson, B. J., Jun 28 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
39 Scopus citations
2016
29 Scopus citations

Image texture features predict renal function decline in patients with autosomal dominant polycystic kidney disease

Kline, T., Korfiatis, P., Edwards, M. E., Bae, K. T., Yu, A., Chapman, A. B., Mrug, M., Grantham, J. J., Landsittel, D., Bennett, W. M., King, B. F., Harris, P. C., Torres, V. & Erickson, B. J., Jul 12 2016, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

17 Scopus citations
58 Scopus citations

Semiautomated segmentation of polycystic kidneys in T2-weighted MR images

Kline, T., Edwards, M. E., Korfiatis, P., Akkus, Z., Torres, V. & Erickson, B. J., Sep 1 2016, In : American Journal of Roentgenology. 207, 3, p. 605-613 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Coronary microcirculation changes in non-ischemic dilated cardiomyopathy identified by novel perfusion CT

Miller, W. L., Behrenbeck, T. R., McCollough, C. H., Williamson, E. E., Leng, S., Kline, T. & Ritman, E. L., Feb 25 2015, (Accepted/In press) In : International Journal of Cardiovascular Imaging.

Research output: Contribution to journalArticle

5 Scopus citations

MIRMAID: A content management system for medical image analysis research

Korfiatis, P., Kline, T., Blezek, D. J., Langer, S. G., Ryan, W. J. & Erickson, B. J., Sep 1 2015, In : Radiographics. 35, 5, p. 1461-1468 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Semi-automated segmentation of pre-operative low grade gliomas in magnetic resonance imaging

Akkus, Z., Sedlar, J., Coufalova, L., Korfiatis, P., Kline, T. L., Warner, J. D., Agrawal, J. & Erickson, B. J., Aug 14 2015, In : Cancer Imaging. 15, 1, 12.

Research output: Contribution to journalArticle

11 Scopus citations
21 Scopus citations
2014

Anatomy of hepatic arteriolo-portal venular shunts evaluated by 3D micro-CT imaging

Kline, T. L., Knudsen, B. E., Anderson, J. L., Vercnocke, A. J., Jorgensen, S. M. & Ritman, E. L., Jun 2014, In : Journal of Anatomy. 224, 6, p. 724-731 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Early changes in myocardial microcirculation in asymptomatic hypercholesterolemic subjects: As detected by perfusion CT

Behrenbeck, T. R., McCollough, C. H., Miller, W. L., Williamson, E. E., Leng, S., Kline, T. L. & Ritman, E. L., 2014, In : Annals of Biomedical Engineering. 42, 3, p. 515-525 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Characterization of the pore labyrinth geometry of sea sponges imaged by micro-CT

Kline, T. L. & Ritman, E. L., Apr 1 2012, In : Journal of Porous Materials. 19, 2, p. 141-151 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Algorithm-enabled low-dose micro-CT imaging

Han, X., Bian, J., Eaker, D. R., Kline, T. L., Sidky, E. Y., Ritman, E. L. & Pan, X., Mar 1 2011, In : IEEE transactions on medical imaging. 30, 3, p. 606-620 15 p., 5609203.

Research output: Contribution to journalArticle

113 Scopus citations

Relating function to branching geometry: A micro-CT study of the hepatic artery, portal vein, and biliary tree

Kline, T. L., Zamir, M. & Ritman, E. L., Oct 1 2011, In : Cells Tissues Organs. 194, 5, p. 431-442 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

SU‐E‐I‐40: Reconstruction of Sparse Images from Few‐View Cone‐Beam Data

Han, X., Bian, J., Eaker, D., Kline, T., Sidky, E., Ritman, E. & Pan, X., Jan 1 2011, In : Medical Physics. 38, 6, p. 3404-3405 2 p.

Research output: Contribution to journalArticle

2010

Accuracy of microvascular measurements obtained from micro-CT images

Kline, T. L., Zamir, M. & Ritman, E. L., Sep 2010, In : Annals of Biomedical Engineering. 38, 9, p. 2851-2864 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

Synchrotron-based micro-CT imaging of the human lung acinus

Litzlbauer, H. D., Korbel, K., Kline, T. L., Jorgensen, S. M., Eaker, D. R., Bohle, R. M., Ritman, E. L. & Langheinrich, A. C., Sep 2010, In : Anatomical Record. 293, 9, p. 1607-1614 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2009

Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Kline, T. L., Xu, Y. H., Jing, Y. & Wang, J. P., May 1 2009, In : Journal of Magnetism and Magnetic Materials. 321, 10, p. 1525-1528 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia

Jing, Y., Sohn, H., Kline, T., Victora, R. H. & Wang, J. P., Apr 27 2009, In : Journal of Applied Physics. 105, 7, 07B305.

Research output: Contribution to journalArticle

16 Scopus citations

Thermal response of superparamagnetic particles suspended in liquid and solid media

Zeng, P., Kline, T. L., Wang, J. P. & Wiedmann, T. S., Mar 1 2009, In : Journal of Magnetism and Magnetic Materials. 321, 5, p. 373-376 4 p.

Research output: Contribution to journalArticle

4 Scopus citations