Timothy J Nelson, MD, PhD

  • 3396 Citations
  • 31 Scopus h-Index
20022020

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Research Output

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2011

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming

Folmes, C. D. L., Nelson, T. J., Martinez-Fernandez, A., Arrell, D. K., Lindor, J. Z., Dzeja, P. P., Ikeda, Y., Perez-Terzic, C. & Terzic, A., Aug 3 2011, In : Cell Metabolism. 14, 2, p. 264-271 8 p.

Research output: Contribution to journalArticle

532 Scopus citations
2010

ATP-sensitive K+ channel-deficient dilated cardiomyopathy proteome remodeled by embryonic stem cell therapy

Zlatkovic-Lindor, J., Arrell, D. K., Yamada, S., Nelson, T. J. & Terzic, A., Aug 1 2010, In : Stem Cells. 28, 8, p. 1355-1367 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cardiogenic induction of pluripotent stem cells streamlined through a conserved SDF-1/VEGF/BMP2 integrated network

Chiriac, A., Nelson, T. J., Faustino, R. S., Behfar, A. & Terzic, A., Sep 10 2010, In : PloS one. 5, 4, e9943.

Research output: Contribution to journalArticle

20 Scopus citations

C-MYC-Independent Nuclear Reprogramming Favors Cardiogenic Potential of Induced Pluripotent Stem Cells

Martinez-Fernandez, A., Nelson, T. J., Ikeda, Y. & Terzic, A., Feb 1 2010, In : Journal of cardiovascular translational research. 3, 1, p. 13-23 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Decoded calreticulin-deficient embryonic stem cell transcriptome resolves latent cardiophenotype

Faustino, R. S., Chiriac, A., Niederlander, N. J., Nelson, T. J., Behfar, A., Mishra, P. K., Macura, S., Michalak, M., Terzic, A. & Perez-Terzic, C., Jul 1 2010, In : Stem Cells. 28, 7, p. 1281-1291 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

SDF-1-enhanced cardiogenesis requires CXCR4 induction in pluripotent stem cells

Chiriac, A., Terzic, A., Park, S., Ikeda, Y., Faustino, R. & Nelson, T. J., Dec 2010, In : Journal of cardiovascular translational research. 3, 6, p. 674-682 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Stem cells: Clinical trials results the end of the beginning or the beginning of the end?

Behfar, A., Crespo-Diaz, R., Nelson, T. J., Terzic, A. & Gersh, B. J., Jan 1 2010, In : Cardiovascular and Hematological Disorders - Drug Targets. 10, 3, p. 186-201 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
2009

Induced pluripotent reprogramming from promiscuous human sternness-related factors

Nelson, T. J., Martinez-Fernandez, A., Yamada, S., Mael, A. A., Terzic, A. & Ikeda, Y., Jan 1 2009, In : Clinical and translational science. 2, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

IPS programmed without c-MYC yield proficient cardiogenesis for functional heart chimerism

Martinez-Fernandez, A., Nelson, T. J., Yamada, S., Reyes, S., Alekseev, A. E., Perez-Terzic, C., Ikeda, Y. & Terzic, A., Sep 1 2009, In : Circulation research. 105, 7, p. 648-656 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

KCNJ11 knockout morula re-engineered by stem cell diploid aggregation

Nelson, T. J., Martinez-Fernandez, A. & Terzic, A., 2009, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 364, 1514, p. 269-276 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Lineage specification of Flk-1+ progenitors is associated with divergent Sox7 expression in cardiopoiesis

Nelson, T. J., Chiriac, A., Faustino, R. S., Crespo-Diaz, R. J., Behfar, A. & Terzic, A., Mar 1 2009, In : Differentiation. 77, 3, p. 248-255 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Repair of acute myocardial infarction with induced pluripotent stem cells induced by human stemness factors

Nelson, T. J., Martinez-Fernandez, A., Yamada, S., Perez-Terzic, C., Ikeda, Y. & Terzic, A., Aug 1 2009, In : Circulation. 120, 5, p. 408-416 9 p.

Research output: Contribution to journalArticle

364 Scopus citations

Stem cell transplant into preimplantation embryo yields myocardial infarction-resistant adult phenotype

Yamada, S., Nelson, T. J., Behfar, A., Crespo-Diaz, R. J., Fraidenraich, D. & Terzic, A., Jul 1 2009, In : Stem Cells. 27, 7, p. 1697-1705 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

CXCR4+/FLK-1+ biomarkers select a cardiopoietic lineage from embryonic stem cells

Nelson, T. J., Faustino, R. S., Chiriac, A., Crespo-Diaz, R., Behfar, A. & Terzic, A., Jun 1 2008, In : Stem Cells. 26, 6, p. 1464-1473 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

Embryonic stem cell therapy of heart failure in genetic cardiomyopathy

Yamada, S., Nelson, T. J., Crespo-Diaz, R. J., Perez-Terzic, C., Liu, X. K., Miki, T., Seino, S., Behfar, A. & Terzic, A., Oct 1 2008, In : Stem Cells. 26, 10, p. 2644-2653 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Stem cells: Biologics for regeneration

Nelson, T. J., Behfar, A. & Terzic, A., Nov 1 2008, In : Clinical pharmacology and therapeutics. 84, 5, p. 620-623 4 p.

Research output: Contribution to journalArticle

39 Scopus citations
2007

A definitive example of a geometric "entatic state" effect: Electron-transfer kinetics for a copper(ll/l) complex involving a quinquedentate macrocyclic trithiaether - Bipyridine ligand

Chaka, G., Sonnenberg, J. L., Schlegel, H. B., Heeg, M. J., Jaeger, G., Nelson, T. J., Ochrymowycz, L. A. & Rorabacher, D. B., Apr 25 2007, In : Journal of the American Chemical Society. 129, 16, p. 5217-5227 11 p.

Research output: Contribution to journalArticle

37 Scopus citations
2006

Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells

Nelson, T. J., Ge, Z. D., Van Orman, J., Barron, M., Rudy-Reil, D., Hacker, T. A., Misra, R., Duncan, S. A., Auchamdpach, J. A. & Lough, J. W., Nov 1 2006, In : Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. 288, 11, p. 1216-1224 9 p.

Research output: Contribution to journalArticle

50 Scopus citations
2005

SRF-dependent gene expression in isolated cardiomyocytes: Regulation of genes involved in cardiac hypertrophy

Nelson, T. J., Balza, R., Xiao, Q. & Misra, R. P., Sep 1 2005, In : Journal of Molecular and Cellular Cardiology. 39, 3, p. 479-489 11 p.

Research output: Contribution to journalArticle

68 Scopus citations
2004

Conserved Enhancer in the Serum Response Factor Promoter Controls Expression during Early Coronary Vasculogenesis

Nelson, T. J., Duncan, S. A. & Misra, R. P., Apr 30 2004, In : Circulation research. 94, 8, p. 1059-1066 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification and Characterization of a Glycosaminoglycan Recognition Element of the C Chemokine Lymphotactin

Peterson, F. C., Elgin, E. S., Nelson, T. J., Zhang, F., Hoeger, T. J., Linhardt, R. J. & Volkman, B. F., Mar 26 2004, In : Journal of Biological Chemistry. 279, 13, p. 12598-12604 7 p.

Research output: Contribution to journalArticle

62 Scopus citations
2002

Electron-transfer kinetics and equilibria of copper(II/I) complexes with 1,4,7-trithiacyclononane. a square scheme mechanism involving ligand addition

Kandegedara, A., Krylova, K., Nelson, T. J., Schroeder, R. R., Ochrymowycz, L. A. & Rorabacher, D. B., Dec 1 2002, In : Dalton Transactions. 5, p. 792-801 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Electron-transfer kinetics and equilibria of copper(II/I) complexes with 1,4,7-trithiacyclononane. A square scheme mechanism involving ligand addition

Kandegedara, A., Krylova, K., Nelson, T. J., Schroeder, R. R., Ochrymowycz, L. A. & Rorabacher, D. B., Nov 19 2002, In : Journal of the Chemical Society, Dalton Transactions. 5, p. 792-801 10 p.

Research output: Contribution to journalArticle

11 Scopus citations