Thomas P Burghardt, PhD

Professor

  • 2762 Citations
  • 25 h-Index
1981 …2018
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  • 2 Similar Profiles
Myosins Medicine & Life Sciences
Muscle Chemical Compounds
Myosin Subfragments Medicine & Life Sciences
Actins Medicine & Life Sciences
Fluorescence Chemical Compounds
Muscles Medicine & Life Sciences
Fluorescence Polarization Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences

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Projects 1990 2015

Myosins
Hypertrophy
Myosin Heavy Chains
Familial Hypertrophic Cardiomyopathy
Mutation
Actomyosin
Myosins
Merging
Adenosine Triphosphate
Conformations
muscles
Muscle
probes
muscle fibers
electron paramagnetic resonance

Research Output 1981 2018

  • 2762 Citations
  • 25 h-Index
  • 110 Article

Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics

Wang, Y., Ajtai, K. & Burghardt, T. P., Nov 21 2018, In : Open Biology. 8, 11

Research output: Contribution to journalArticle

Cardiac Myosins
Myosins
Mechanics
Actins
Substrates

Neural/Bayes network predictor for inheritable cardiac disease pathogenicity and phenotype

Burghardt, T. P. & Ajtai, K., Jun 1 2018, In : Journal of Molecular and Cellular Cardiology. 119, p. 19-27 9 p.

Research output: Contribution to journalArticle

Virulence
Heart Diseases
Phenotype
Single Nucleotide Polymorphism
Databases
5 Citations (Scopus)

Single cardiac ventricular myosins are autonomous motors

Wang, Y., Yuan, C. C., Kazmierczak, K., Szczesna-Cordary, D. & Burghardt, T. P., Jan 1 2018, In : Open Biology. 4, 8, 170240.

Research output: Contribution to journalArticle

Cardiac Myosins
Ventricular Myosins
Myosins
Muscle
Actins

Uncured PDMS inhibits myosin in vitro motility in a microfluidic flow cell

Wang, Y. & Burghardt, T. P., Dec 15 2018, In : Analytical Biochemistry. 563, p. 56-60 5 p.

Research output: Contribution to journalArticle

Microfluidics
Myosins
Glass
Assays
Cell Aging
6 Citations (Scopus)

Auxotonicto isometric contraction transitioning in a beating heart causes Myosin step-size to down shift

Burghardt, T. P., Sun, X., Wang, Y. & Ajtai, K., Apr 1 2017, In : PLoS One. 12, 4, e0174690.

Research output: Contribution to journalArticle

Isometric Contraction
Myosins
myosin
heart
Actins