• 32763 Citations
  • 77 Scopus h-Index
1980 …2020

Research output per year

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Research Output

2020

Delta-like Protein 3 Expression and Targeting in Merkel Cell Carcinoma

Xie, H., Kaye, F. J., Isse, K., Sun, Y., Ramoth, J., French, D. M., Flotte, T. J., Luo, Y., Saunders, L. R. & Mansfield, A. S., Jan 1 2020, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Classification of melanocytic lesions in selected and whole-slide images via convolutional neural networks

Hart, S., Flotte, W., Norgan, A. P., Shah, K. K., Buchan, Z. R., Mounajjed, T. & Flotte, T. J., Jan 1 2019, In : Journal of Pathology Informatics. 10, 1, 5.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Identification of novel, immune-mediating extracellular vesicles in human lymphatic effluent draining primary cutaneous melanoma

Maus, R. L. G., Jakub, J. W., Hieken, T. J., Nevala, W. K., Christensen, T. A., Sutor, S. L., Flotte, T. J. & Markovic, S. N., Dec 2 2019, In : OncoImmunology. 8, 12, e1667742.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mutational Profile in Vulvar, Vaginal, and Urethral Melanomas: Review of 37 Cases with Focus on Primary Tumor Site

Zarei, S., Voss, J. S., Jin, L., Jenkins, S. M., Bryce, A. H., Erickson, L. A., Bell, D. A., Kipp, B. R. & Flotte, T. J., Jan 1 2019, (Accepted/In press) In : International Journal of Gynecological Pathology.

Research output: Contribution to journalReview article

Robust hierarchical density estimation and regression for re-stained histological whole slide image co-registration

Jiang, J., Larson, N. B., Prodduturi, N., Flotte, T. J. & Hart, S. N., 2019, In : PloS one. 14, 7, e0220074.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Understanding heterogeneous tumor microenvironment in metastatic melanoma

Yan, Y., Leontovich, A. A., Gerdes, M. J., Desai, K., Dong, J., Sood, A., Santamaria-Pang, A., Mansfield, A. S., Chadwick, C., Zhang, R., Nevala, W. K., Flotte, T. J., Ginty, F. & Markovic, S. N., Jun 2019, In : PloS one. 14, 6, e0216485.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

99 Scopus citations

Anatomical pathology is at a crossroads

Flotte, T. J. & Bell, D. A., Jan 1 2018, (Accepted/In press) In : Pathology.

Research output: Contribution to journalArticle

5 Scopus citations

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

262 Scopus citations

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

49 Scopus citations

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

27 Scopus citations

CD206-positive myeloid cells bind galectin-9 and promote a tumor-supportive microenvironment

Enninga, E. A. L., Chatzopoulos, K., Butterfield, J. T., Sutor, S. L., Leontovich, A. A., Nevala, W. K., Flotte, T. J. & Markovic, S. N., Aug 1 2018, In : Journal of Pathology. 245, 4, p. 468-477 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journalArticle

269 Scopus citations

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer cell. 33, 4, p. 721-735.e8

Research output: Contribution to journalArticle

77 Scopus citations
2 Scopus citations

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

The Cancer Genome Atlas Research Network, Aug 13 2018, In : Cancer cell. 34, 2, p. 211-224.e6

Research output: Contribution to journalArticle

110 Scopus citations

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journalArticle

303 Scopus citations

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

36 Scopus citations

Cytotechnologists as coinvestigators in anatomical pathology research

Kopp, K. J., Passow, M. R., Del Rosario, K. M., Christensen, M. R., O'Shaughnessy, J. W., Bartholet, M. K., Francis, M. E. & Flotte, T. J., Jan 1 2018, (Accepted/In press) In : Cancer cytopathology.

Research output: Contribution to journalArticle

3 Scopus citations

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 227-238.e3

Research output: Contribution to journalArticle

95 Scopus citations

Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

The MC3 Working Group & The Cancer Genome Atlas Research Network, Aug 9 2018, In : Cell. 174, 4, p. 1034-1035 2 p.

Research output: Contribution to journalComment/debate

61 Scopus citations
28 Scopus citations

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

53 Scopus citations

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer cell. 33, 4, p. 676-689.e3

Research output: Contribution to journalArticle

99 Scopus citations

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 239-254.e6

Research output: Contribution to journalArticle

135 Scopus citations

Histological features and outcome of inverted type-A melanocytic nevi

Dadras, S. S., Lu, J., Zembowicz, A., Flotte, T. J. & Mihm, M. C., Apr 1 2018, In : Journal of Cutaneous Pathology. 45, 4, p. 254-262 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

21 Scopus citations

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer cell. 33, 4, p. 706-720.e9

Research output: Contribution to journalArticle

131 Scopus citations

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 172-180.e3

Research output: Contribution to journalArticle

28 Scopus citations

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journalArticle

145 Scopus citations

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 255-269.e4

Research output: Contribution to journalArticle

34 Scopus citations

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journalArticle

345 Scopus citations

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journalArticle

56 Scopus citations

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 297-312.e12

Research output: Contribution to journalArticle

88 Scopus citations

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journalArticle

138 Scopus citations

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journalArticle

73 Scopus citations

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journalArticle

104 Scopus citations

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 282-296.e4

Research output: Contribution to journalArticle

75 Scopus citations

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 181-193.e7

Research output: Contribution to journalArticle

106 Scopus citations

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 270-281.e3

Research output: Contribution to journalArticle

43 Scopus citations

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAFV600E-mutant melanoma

Harris, A. L., Lee, S. E., Dawson, L. K., Marlow, L. A., Edenfield, B. H., Durham, W. F., Flotte, T. J., Thompson, M., Small, D. L., Synnott, A. J., Markovic, S. N. & Copland, J. A., 2018, In : Oncotarget. 9, 13, p. 10905-10919 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 313-326.e5

Research output: Contribution to journalArticle

112 Scopus citations

The Immune Landscape of Cancer

The Cancer Genome Atlas Research Network, Apr 17 2018, In : Immunity. 48, 4, p. 812-830.e14

Research output: Contribution to journalArticle

485 Scopus citations
2015

Acute cutaneous graft-vs.-host disease compared to drug hypersensitivity reaction with vacuolar interface changes: A blinded study of microscopic and immunohistochemical features

Lehman, J. S., Gibson, L. E., El-Azhary, R. A., Chavan, R. N., Hashmi, S. K., Lohse, C. M. & Flotte, T. J., Jan 1 2015, In : Journal of Cutaneous Pathology. 42, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Expression of the chemokine receptor gene, CCR8, is associated with DUSP22 rearrangements in anaplastic large cell lymphoma

Xing, X., Flotte, T. J., Law, M. E., Blahnik, A. J., Chng, W. J., Huang, G., Knudson, R. A., Ketterling, R. P., Porcher, J. C., Ansell, S. M., Sidhu, J., Dogan, A. & Feldman, A. L., Sep 23 2015, In : Applied Immunohistochemistry and Molecular Morphology. 23, 8, p. 580-589 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Dendritic cells are prominent in granuloma annulare

Chavan, R. N., Lehman, J. S. & Flotte, T. J., Jan 1 2014, In : Journal of the American Academy of Dermatology. 71, 5, p. 1020-1022 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Preappointment testing for BRAF/KIT mutation in advanced melanoma: A model in molecular data delivery for individualized medicine

Mounajjed, T., Brown, C. L., Stern, T. K., Bjorheim, A. M., Bridgeman, A. J., Rumilla, K. M., McWilliams, R. R. & Flotte, T. J., Nov 1 2014, In : Human Pathology. 45, 11, p. 2240-2246 7 p.

Research output: Contribution to journalArticle

2013

Dermal and conjunctival melanocytic proliferations in diffuse uveal melanocytic proliferation

Pulido, J. S., Flotte, T. J., Raja, H., Miles, S., Winters, J. L., Niles, R., Jaben, E. A., Markovic, S. N., Davies, J., Kalli, K. R., Vile, R. G., Garcia, J. J. & Salomao, D. R., Sep 2013, In : Eye (Basingstoke). 27, 9, p. 1058-1062 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mass spectrometry-based proteomic analysis of cutaneous cryoglobulinaemia in formalin-fixed tissues

Shon, W., Dogan, A., Camilleri, M. J., Erickson, L. A. & Flotte, T. J., May 1 2013, In : British Journal of Dermatology. 168, 5, p. 1128-1130 3 p.

Research output: Contribution to journalLetter

2012

Increased diagnosis of thin superficial spreading melanomas: A 20-year study

Frangos, J. E., Duncan, L. M., Piris, A., Nazarian, R. M., Mihm, M. C., Hoang, M. P., Gleason, B., Flotte, T. J., Byers, H. R., Barnhill, R. L. & Kimball, A. B., Sep 1 2012, In : Journal of the American Academy of Dermatology. 67, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

41 Scopus citations