• 4179 Citations
  • 31 Scopus h-Index
20052019
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Research Output 2005 2019

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Article
2019
6 Citations (Scopus)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., De Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Mitochondria
Mitochondrial DNA
Genes
Waist-Hip Ratio
Open Access
Case-Control Studies
Electronic Health Records
Research
Epidemiologic Studies
Cohort Studies

Circulating adhesion molecules and subclinical interstitial lung disease: the Multi-Ethnic Study of Atherosclerosis

McGroder, C. F., Aaron, C. P., Bielinski, S. J., Kawut, S. M., Tracy, R. P., Raghu, G., Barr, R. G., Lederer, D. J. & Podolanczuk, A. J., Sep 1 2019, In : The European respiratory journal. 54, 3

Research output: Contribution to journalArticle

Open Access
Interstitial Lung Diseases
P-Selectin
Atherosclerosis
Vascular Cell Adhesion Molecule-1
Independent Living
1 Citation (Scopus)

Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network

the eMERGE Consortium, Sep 5 2019, In : American journal of human genetics. 105, 3, p. 588-605 18 p.

Research output: Contribution to journalArticle

Genetic Testing
Clinical Decision Support Systems
Precision Medicine
Gene Targeting
Information Dissemination

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

Ward-Caviness, C. K., De Vries, P. S., Wiggins, K. L., Huffman, J. E., Yanek, L. R., Bielak, L. F., Giulianini, F., Guo, X., Kleber, M. E., Kacprowski, T., Groß, S., Petersman, A., Smith, G. D., Hartwig, F. P., Bowden, J., Hemani, G., Müller-Nuraysid, M., Strauch, K., Koenig, W., Waldenberger, M. & 38 others, Meitinger, T., Pankratz, N., Boerwinkle, E., Tang, W., Fu, Y. P., Johnson, A. D., Song, C., De Maat, M. P. M., Uitterlinden, A. G., Franco, O. H., Brody, J. A., McKnight, B., Chen, Y. D. I., Psaty, B. M., Mathias, R. A., Becker, D. M., Peyser, P. A., Smith, J. A., Bielinski, S. J., Ridker, P. M., Taylor, K. D., Yao, J., Tracy, R., Delgado, G., Trompet, S., Sattar, N., Jukema, J. W., Becker, L. C., Kardia, S. L. R., Rotter, J. I., März, W., Dörr, M., Chasman, D. I., Dehghan, A., O’Donnell, C. J., Smith, N. L., Peters, A. & Morrison, A. C., May 1 2019, In : PloS one. 14, 5, e0216222.

Research output: Contribution to journalArticle

Open Access
fibrinogen
Random Allocation
Fibrinogen
Coronary Disease
Mendelian Randomization Analysis
2 Citations (Scopus)

Pharmacogenomic next-generation DNA sequencing: Lessons from the identification and functional characterization of variants of unknown significance in CYP2C9 and CYP2C19

Devarajan, S., Moon, I., Ho, M. F., Larson, N., Neavin, D. R., Moyer, A., Black, J. L., Bielinski, S. J., Scherer, S. E., Wang, L. M., Weinshilboum, R. M. & Reid, J. M., Apr 1 2019, In : Drug Metabolism and Disposition. 47, 4, p. 425-435 11 p.

Research output: Contribution to journalArticle

Pharmacogenetics
DNA Sequence Analysis
Cytochrome P-450 Enzyme System
Oxidoreductases
Proteins
2018
3 Citations (Scopus)

Ethnic, geographic, and genetic differences in arsenic metabolism at low arsenic exposure: A preliminary analysis in the multi-ethnic study of atherosclerosis (mesa)

Balakrishnan, P., Jones, M. R., Vaidya, D., Tellez-Plaza, M., Post, W. S., Kaufman, J. D., Bielinski, S. J., Taylor, K., Francesconi, K., Goessler, W. & Navas-Acien, A., Jun 5 2018, In : International Journal of Environmental Research and Public Health. 15, 6, 1179.

Research output: Contribution to journalArticle

Arsenic
Atherosclerosis
Cacodylic Acid
Seafood
Methyltransferases
1 Citation (Scopus)

Hepatocyte growth factor is associated with progression of atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bell, E. J., Decker, P. A., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Wassel, C. L., Larson, N., Cohoon, K. P., Budoff, M. J., Polak, J. F., Stein, J. H. & Bielinski, S. J., May 1 2018, In : Atherosclerosis. 272, p. 162-167 6 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Atherosclerosis
Coronary Vessels
Calcium
Confounding Factors (Epidemiology)
1 Citation (Scopus)

The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis

Fernández-Rhodes, L., Malinowski, J. R., Wang, Y., Tao, R., Pankratz, N., Jeff, J. M., Yoneyama, S., Carty, C. L., Setiawan, V. W., Le Marchand, L., Haiman, C., Corbett, S., Demerath, E., Heiss, G., Gross, M., Buzkova, P., Crawford, D. C., Hunt, S. C., Rao, D. C., Schwander, K. & 25 others, Chakravarti, A., Gottesman, O., Abul-Husn, N. S., Bottinger, E. P., Loos, R. J. F., Raffel, L. J., Yao, J., Guo, X., Bielinski, S. J., Rotter, J. I., Vaidya, D., Chen, Y. D. I., Castañeda, S. F., Daviglus, M., Kaplan, R., Talavera, G. A., Ryckman, K. K., Peters, U., Ambite, J. L., Buyske, S., Hindorff, L., Kooperberg, C., Matise, T., Franceschini, N. & North, K. E., Jul 1 2018, In : PLoS One. 13, 7, e0200486.

Research output: Contribution to journalArticle

menarche
menopause
Epidemiology
Menarche
Menopause
2017
1 Citation (Scopus)

ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Pike, M. M., Larson, N., Wassel, C. L., Cohoon, K. P., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Decker, P. A., Berardi, C., Alexander, K. S., Cushman, M., Zakai, N. A. & Bielinski, S. J., May 1 2017, In : Thrombosis Research. 153, p. 1-6 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Blood Group Antigens
African Americans
Atherosclerosis
Ankle Brachial Index
4 Citations (Scopus)

A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Cannone, V., Scott, C. G., Decker, P. A., Larson, N., Palmas, W., Taylor, K. D., Wang, T. J., Gupta, D. K., Bielinski, S. J. & Burnett, J. C. J., Dec 1 2017, In : PLoS One. 12, 12, e0189858.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
African Americans
atherosclerosis
Atherosclerosis
Brain Natriuretic Peptide
3 Citations (Scopus)

A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

MEDIA Consortium, Mar 1 2017, In : PLoS One. 12, 3, e0172577.

Research output: Contribution to journalArticle

African Americans
Medical problems
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
7 Citations (Scopus)

CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications

St. Sauver, J., Olson, J. E., Roger, V. L., Nicholson, W. T., Black, J. L., Takahashi, P. Y., Caraballo, P., Bell, E. J., Jacobson, D. J., Larson, N. & Bielinski, S. J., Jul 24 2017, In : Pharmacogenomics and Personalized Medicine. 10, p. 217-227 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Opioid Analgesics
Phenotype
Pain
Prescriptions
1 Citation (Scopus)

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N., Kirsch, P. S., De Andrade, M., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Atherosclerosis
Proteins
Peripheral Arterial Disease
Secretory Leukocyte Peptidase Inhibitor
10 Citations (Scopus)

Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations

Avery, C. L., Wassel, C. L., Richard, M. A., Highland, H. M., Bien, S., Zubair, N., Soliman, E. Z., Fornage, M., Bielinski, S. J., Tao, R., Seyerle, A. A., Shah, S. J., Lloyd-Jones, D. M., Buyske, S., Rotter, J. I., Post, W. S., Rich, S. S., Hindorff, L. A., Jeff, J. M., Shohet, R. V. & 8 others, Sotoodehnia, N., Lin, D. Y., Whitsel, E. A., Peters, U., Haiman, C. A., Crawford, D. C., Kooperberg, C. & North, K. E., Apr 1 2017, In : Heart Rhythm. 14, 4, p. 572-580 9 p.

Research output: Contribution to journalArticle

Hispanic Americans
Single Nucleotide Polymorphism
Population
Genome-Wide Association Study
Biodiversity
9 Citations (Scopus)

Genome-wide study of resistant hypertension identified from electronic health records

Dumitrescu, L., Ritchie, M. D., Denny, J. C., Rouby, N. M. E., McDonough, C. W., Bradford, Y., Ramirez, A. H., Bielinski, S. J., Basford, M. A., Chai, H. S., Peissig, P., Carrell, D., Pathak, J., Rasmussen, L. V., Wang, X., Pacheco, J. A., Kho, A. N., Hayes, M. G., Matsumoto, M., Smith, M. E. & 15 others, Li, R., Cooper-DeHoff, R. M., Kullo, I. J., Chute, C. G., Chisholm, R. L., Jarvik, G. P., Larson, E. B., Carey, D., McCarty, C. A., Williams, M. S., Roden, D. M., Bottinger, E., Johnson, J. A., De Andrade, M. & Crawford, D. C., Feb 1 2017, In : PLoS One. 12, 2, e0171745.

Research output: Contribution to journalArticle

Electronic Health Records
hypertension
electronics
Genes
Blood pressure
3 Citations (Scopus)

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Coronary Disease
Biomarkers
Hispanic Americans
African Americans
2 Citations (Scopus)

Increased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6

Takahashi, P. Y., Ryu, E., Pathak, J., Jenkins, G. D., Batzler, A., Hathcock, M. A., Black, J. L., Olson, J. E., Cerhan, J. R. & Bielinski, S. J., Feb 14 2017, In : Pharmacogenomics and Personalized Medicine. 10, p. 39-47 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Hospitalization
Hospital Emergency Service
Confidence Intervals
Phenotype
1 Citation (Scopus)

Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants

Steffen, B. T., Bielinski, S. J., Decker, P. A., Berardi, C., Larson, N., Pankow, J. S., Michos, E. D., Hanson, N. Q., Herrington, D. M. & Tsai, M. Y., 2017, (Accepted/In press) In : Journal of Clinical Lipidology.

Research output: Contribution to journalArticle

HDL Lipoproteins
LDL Cholesterol
HDL Cholesterol
Atherosclerosis
Selectins
26 Citations (Scopus)

Multidisciplinary model to implement pharmacogenomics at the point of care

Caraballo, P., Hodge, L. S., Bielinski, S. J., Stewart, A. K., Farrugia, G., Schultz, C. G., Rohrer-Vitek, C. R., Olson, J. E., St. Sauver, J., Roger, V. L., Parkulo, M. A., Kullo, I. J., Nicholson, W. T., Elliott, M. A., Black, J. L. & Weinshilboum, R. M., Apr 1 2017, In : Genetics in Medicine. 19, 4, p. 421-429 9 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Clinical Decision Support Systems
Pharmacogenetics
Drug Interactions
Clinical Governance
16 Citations (Scopus)

Participant-perceived understanding and perspectives on pharmacogenomics: The Mayo Clinic RIGHT protocol (Right Drug, Right Dose, Right Time)

Olson, J. E., Rohrer Vitek, C. R., Bell, E. J., McGree, M. E., Jacobson, D. J., St. Sauver, J., Caraballo, P., Griffin, J., Roger, V. L. & Bielinski, S. J., Jul 1 2017, In : Genetics in Medicine. 19, 7, p. 819-825 7 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Cytochrome P-450 CYP2D6
Pharmaceutical Preparations
Viverridae
Education
39 Citations (Scopus)

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium & 1 others, SIGMA T2D Consortium, Jun 29 2017, In : Cell. 170, 1, p. 199-212.e20

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Haplotypes
CD147 Antigens
Mexico
4 Citations (Scopus)

Variability in assigning pathogenicity to incidental findings: insights from LDLR sequence linked to the electronic health record in 1013 individuals

Safarova, M. S., Klee, E. W., Baudhuin, L. M., Winkler, E. M., Kluge, M. L., Bielinski, S. J., Olson, J. E. & Kullo, I. J., Feb 1 2017, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Incidental Findings
Electronic Health Records
Virulence
Hyperlipoproteinemia Type II
Medical Genetics
2016
9 Citations (Scopus)

ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis

Larson, N., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., Pankow, J. S., Tang, W., Hanson, N. Q., Alexander, K., Zakai, N. A., Cushman, M. & Bielinski, S. J., Aug 1 2016, In : Atherosclerosis. 251, p. 422-429 8 p.

Research output: Contribution to journalArticle

Selectins
Blood Group Antigens
Atherosclerosis
Alleles
von Willebrand Factor
6 Citations (Scopus)
Hospitalization
Social Class
Population
Logistic Models
Proportional Hazards Models
6 Citations (Scopus)

Are patients willing to incur out-of-pocket costs for pharmacogenomic testing?

Bielinski, S. J., St. Sauver, J., Olson, J. E., Wieland, M. L., Vitek, C. R., Bell, E. J., Mc Gree, M. E., Jacobson, D. J., McCormick, J. B., Takahashi, P. Y., Black, J. L., Caraballo, P., Sharp, R. R., Beebe, T. J., Weinshilboum, R. M., Wang, L. M. & Roger, V. L., Oct 25 2016, (Accepted/In press) In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

Health Expenditures
Pharmacogenomic Testing
88 Citations (Scopus)

Association of arrhythmia-related genetic variants with phenotypes documented in electronic medical records

Van Driest, S. L., Wells, Q. S., Stallings, S., Bush, W. S., Gordon, A., Nickerson, D. A., Kim, J. H., Crosslin, D. R., Jarvik, G. P., Carrell, D. S., Ralston, J. D., Larson, E. B., Bielinski, S. J., Olson, J. E., Ye, Z., Kullo, I. J., Abul-Husn, N. S., Scott, S. A., Bottinger, E., Almoguera, B. & 25 others, Connolly, J., Chiavacci, R., Hakonarson, H., Rasmussen-Torvik, L. J., Pan, V., Persell, S. D., Smith, M., Chisholm, R. L., Kitchner, T. E., He, M. M., Brilliant, M. H., Wallace, J. R., Doheny, K. F., Shoemaker, M. B., Li, R., Manolio, T. A., Callis, T. E., Macaya, D., Williams, M. S., Carey, D., Kapplinger, J. D., Ackerman, M. J., Ritchie, M. D., Denny, J. C. & Roden, D. M., Jan 5 2016, In : JAMA - Journal of the American Medical Association. 315, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

Electronic Health Records
Cardiac Arrhythmias
Phenotype
International Classification of Diseases
Gene Frequency

Blood group antigen loci demonstrate multivariate genetic associations with circulating cellular adhesion protein levels in the Multi-Ethnic Study of Atherosclerosis

Larson, N., Decker, P. A., Wassel, C. L., Pankow, J. S., Tang, W., Hanson, N. Q., Tsai, M. Y. & Bielinski, S. J., Feb 16 2016, (Accepted/In press) In : Human Genetics. p. 1-9 9 p.

Research output: Contribution to journalArticle

Blood Group Antigens
Atherosclerosis
Proteins
Quantitative Trait Loci
Genome
10 Citations (Scopus)

Circulating cellular adhesion molecules and risk of diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

Pankow, J. S., Decker, P. A., Berardi, C., Hanson, N. Q., Sale, M., Tang, W., Kanaya, A. M., Larson, N., Tsai, M. Y., Wassel, C. L. & Bielinski, S. J., Jul 1 2016, In : Diabetic Medicine. 33, 7, p. 985-991 7 p.

Research output: Contribution to journalArticle

E-Selectin
Intercellular Adhesion Molecule-1
Atherosclerosis
Vascular Cell Adhesion Molecule-1
Cadherins
10 Citations (Scopus)

Circulating level of hepatocyte growth factor predicts incidence of type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bancks, M. P., Bielinski, S. J., Decker, P. A., Hanson, N. Q., Larson, N., Sicotte, H., Wassel, C. L. & Pankow, J. S., Mar 1 2016, In : Metabolism: Clinical and Experimental. 65, 3, p. 64-72 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Type 2 Diabetes Mellitus
Atherosclerosis
Incidence
Social Adjustment
10 Citations (Scopus)

EMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

Verma, A., Verma, S. S., Pendergrass, S. A., Crawford, D. C., Crosslin, D. R., Kuivaniemi, H., Bush, W. S., Bradford, Y., Kullo, I. J., Bielinski, S. J., Li, R., Denny, J. C., Peissig, P., Hebbring, S., De Andrade, M., Ritchie, M. D. & Tromp, G., Aug 12 2016, In : BMC Medical Genomics. 9, 32.

Research output: Contribution to journalArticle

International Classification of Diseases
Electronic Health Records
Genomics
Phenotype
Clinical Studies
9 Citations (Scopus)

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Zubair, N., Graff, M., Ambite, J. L., Bush, W. S., Kichaev, G., Lu, Y., Manichaikul, A., Sheu, W. H. H., Absher, D., Assimes, T. L., Bielinski, S. J., Bottinger, E. P., Buzkova, P., Chuang, L. M., Chung, R. H., Cochran, B., Dumitrescu, L., Gottesman, O., Haessler, J. W., Haiman, C. & 37 others, Heiss, G., Hsiung, C. A., Hung, Y. J., Hwu, C. M., Juang, J. M. J., Marchand, L. L., Lee, I. T., Lee, W. J., Lin, L. A., Lin, D., Lin, S. Y., Mackey, R. H., Martin, L. W., Pasaniuc, B., Peters, U., Predazzi, I., Quertermous, T., Reiner, A. P., Robinson, J., Rotter, J. I., Ryckman, K. K., Schreiner, P. J., Stahl, E., Tao, R., Tsai, M. Y., Waite, L. L., Wang, T. D., Buyske, S., Chen, Y. D. I., Cheng, I., Crawford, D. C., Loos, R. J. F., Rich, S. S., Fornage, M., North, K. E., Kooperberg, C. & Carty, C. L., 2016, In : Human Molecular Genetics. 25, 24, p. 5500-5512 13 p.

Research output: Contribution to journalArticle

Lipids
Population
Hispanic Americans
African Americans
Asian Americans
57 Citations (Scopus)

Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network

Bush, W. S., Crosslin, D. R., Owusu-Obeng, A., Wallace, J., Almoguera, B., Basford, M. A., Bielinski, S. J., Carrell, D. S., Connolly, J. J., Crawford, D., Doheny, K. F., Gallego, C. J., Gordon, A. S., Keating, B., Kirby, J., Kitchner, T., Manzi, S., Mejia, A. R., Pan, V., Perry, C. L. & 31 others, Peterson, J. F., Prows, C. A., Ralston, J., Scott, S. A., Scrol, A., Smith, M., Stallings, S. C., Veldhuizen, T., Wolf, W., Volpi, S., Wiley, K., Li, R., Manolio, T., Bottinger, E., Brilliant, M. H., Carey, D., Chisholm, R. L., Chute, C. G., Haines, J. L., Hakonarson, H., Harley, J. B., Holm, I. A., Kullo, I. J., Jarvik, G. P., Larson, E. B., McCarty, C. A., Williams, M. S., Denny, J. C., Rasmussen-Torvik, L. J., Roden, D. M. & Ritchie, M. D., Aug 1 2016, In : Clinical Pharmacology and Therapeutics. p. 160-169 10 p.

Research output: Contribution to journalArticle

Electronic Health Records
Genomics
Precision Medicine
Pharmacogenetics
Pharmaceutical Preparations
4 Citations (Scopus)

Hepatocyte growth factor is positively associated with risk of stroke: The MESA (Multi-Ethnic Study of Atherosclerosis)

Bell, E. J., Larson, N., Decker, P. A., Pankow, J. S., Tsai, M. Y., Hanson, N. Q., Wassel, C. L., Longstreth, W. T. & Bielinski, S. J., Nov 1 2016, In : Stroke. 47, 11, p. 2689-2694 6 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Atherosclerosis
Stroke
Confidence Intervals
Confounding Factors (Epidemiology)
6 Citations (Scopus)

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. & Bielinski, S. J., Jan 1 2016, In : Obesity. 24, 1, p. 223-230 8 p.

Research output: Contribution to journalArticle

Adiposity
Atherosclerosis
Intra-Abdominal Fat
Waist-Hip Ratio
Selectins
13 Citations (Scopus)

Improvement in Cardiovascular Risk Prediction with Electronic Health Records

Pike, M. M., Decker, P. A., Larson, N., St. Sauver, J., Takahashi, P. Y., Roger, V. L., Rocca, W. A., Miller, V. M., Olson, J. E., Pathak, J. & Bielinski, S. J., Mar 9 2016, (Accepted/In press) In : Journal of Cardiovascular Translational Research. p. 1-9 9 p.

Research output: Contribution to journalArticle

Electronic Health Records
Cardiovascular Diseases
Area Under Curve
Health
27 Citations (Scopus)

Integrating Pharmacogenomics into Clinical Practice: Promise vs Reality

St. Sauver, J., Bielinski, S. J., Olson, J. E., Bell, E. J., Mc Gree, M. E., Jacobson, D. J., McCormick, J. B., Caraballo, P., Takahashi, P. Y., Roger, V. L. & Rohrer Vitek, C. R., Oct 1 2016, In : American Journal of Medicine. 129, 10, p. 1093-1099.e1

Research output: Contribution to journalArticle

Pharmacogenetics
Prescriptions
Primary Health Care
Clinical Decision Support Systems
Electronic Health Records

Lymphocyte activation gene 3 and coronary artery disease

Golden, D., Kolmakova, A., Sura, S., Vella, A. T., Manichaikul, A., Wang, X. Q., Bielinski, S. J., Taylor, K. D., Chen, Y. D. I., Rich, S. S. & Rodriguez, A., Oct 20 2016, In : JCI insight. 1, 17, p. e88628

Research output: Contribution to journalArticle

Lymphocyte Activation
Coronary Artery Disease
Atherosclerosis
Genes
HDL Cholesterol
3 Citations (Scopus)

Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic association studies

Jackson, K. L., Mbagwu, M., Pacheco, J. A., Baldridge, A. S., Viox, D. J., Linneman, J. G., Shukla, S. K., Peissig, P. L., Borthwick, K. M., Carrell, D. A., Bielinski, S. J., Kirby, J. C., Denny, J. C., Mentch, F. D., Vazquez, L. M., Rasmussen-Torvik, L. J. & Kho, A. N., Nov 17 2016, In : BMC Infectious Diseases. 16, 1, 684.

Research output: Contribution to journalArticle

Electronic Health Records
Genetic Association Studies
Methicillin-Resistant Staphylococcus aureus
Phenotype
Genome-Wide Association Study
54 Citations (Scopus)

Preemptive Pharmacogenomic Testing for Precision Medicine: A Comprehensive Analysis of Five Actionable Pharmacogenomic Genes Using Next-Generation DNA Sequencing and a Customized CYP2D6 Genotyping Cascade

Ji, Y., Skierka, J. M., Blommel, J. H., Moore, B. E., Vancuyk, D. L., Bruflat, J. K., Peterson, L. M., Veldhuizen, T. L., Fadra, N., Peterson, S. E., Lagerstedt, S. A., Train, L. J., Baudhuin, L. M., Klee, E. W., Ferber, M. J., Bielinski, S. J., Caraballo, P., Weinshilboum, R. M. & Black, J. L., May 1 2016, In : Journal of Molecular Diagnostics. 18, 3, p. 438-445 8 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Precision Medicine
Pharmacogenetics
DNA Sequence Analysis
Genes
10 Citations (Scopus)

Variant discovery and fine mapping of genetic loci associated with blood pressure traits in Hispanics and African Americans

Franceschini, N., Carty, C. L., Lu, Y., Tao, R., Sung, Y. J., Manichaikul, A., Haessler, J., Fornage, M., Schwander, K., Zubair, N., Bien, S., Hindorff, L. A., Guo, X., Bielinski, S. J., Ehret, G., Kaufman, J. D., Rich, S. S., Carlson, C. S., Bottinger, E. P., North, K. E. & 6 others, Rao, D. C., Chakravarti, A., Barrett, P. Q., Loos, R. J. F., Buyske, S. & Kooperberg, C., Oct 1 2016, In : PLoS One. 11, 10, e0164132.

Research output: Contribution to journalArticle

Hispanic Americans
Genetic Loci
Blood pressure
African Americans
chromosome mapping
2015
11 Citations (Scopus)

A Robust e-Epidemiology Tool in Phenotyping Heart Failure with Differentiation for Preserved and Reduced Ejection Fraction: the Electronic Medical Records and Genomics (eMERGE) Network

Bielinski, S. J., Pathak, J., Carrell, D. S., Takahashi, P. Y., Olson, J. E., Larson, N., Liu, H. D., Sohn, S., Wells, Q. S., Denny, J. C., Rasmussen-Torvik, L. J., Pacheco, J. A., Jackson, K. L., Lesnick, T. G., Gullerud, R. E., Decker, P. A., Pereira, N. L., Ryu, E., Dart, R. A., Peissig, P. & 7 others, Linneman, J. G., Jarvik, G. P., Larson, E. B., Bock, J. A., Tromp, G. C., De Andrade, M. & Roger, V. L., Jul 21 2015, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

Electronic Health Records
Genomics
Epidemiology
Heart Failure
Research
4 Citations (Scopus)
Electronic Health Records
Health Behavior
Hospitalization
Quality of Life
Health
17 Citations (Scopus)

Intercellular adhesion molecule 1 and progression of percent emphysema: The MESA Lung Study

Aaron, C. P., Schwartz, J. E., Bielinski, S. J., Hoffman, E. A., Austin, J. H. M., Oelsner, E. C., Donohue, K. M., Kalhan, R., Berardi, C., Kaufman, J. D., Jacobs, D. R., Tracy, R. P. & Barr, R. G., Feb 1 2015, In : Respiratory Medicine. 109, 2, p. 255-264 10 p.

Research output: Contribution to journalArticle

Emphysema
Intercellular Adhesion Molecule-1
Atherosclerosis
E-Selectin
Lung

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

Day, F. R., Ruth, K. S., Thompson, D. J., Lunetta, K. L., Pervjakova, N., Chasman, D. I., Stolk, L., Finucane, H. K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A. D., Elks, C. E., Franceschini, N., He, C., Altmaier, E., Brody, J. A., Franke, L. L., Huffman, J. E., Keller, M. F. & 221 others, McArdle, P. F., Nutile, T., Porcu, E., Robino, A., Rose, L. M., Schick, U. M., Smith, J. A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J. J., Mangino, M., Smith, A. V., Tanaka, T., Abecasis, G. R., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C., Arndt, V., Arnold, A. M., Barbieri, C., Beckmann, M. W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S. J., Blomqvist, C., Boerwinkle, E., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Borresen-Dale, A. L., Boutin, T. S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S. J., Chapman, J. R., Ida Chen, Y. D., Chenevix-Trench, G., Couch, F. J., Coviello, A. D., Cox, A., Czene, K., Darabi, H., De Vivo, I., Demerath, E. W., Dennis, J., Devilee, P., Dörk, T., Dos-Santos-Silva, I., Dunning, A. M., Eicher, J. D., Fasching, P. A., Faul, J. D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M. E., Garciá-Closas, M., Giles, G. G., Girotto, G. G., Goldberg, M. S., González-Neira, A., Goodarzi, M. O., Grove, M. L., Gudbjartsson, D. F., Guénel, P., Guo, X., Haiman, C. A., Hall, P., Hamann, U., Henderson, B. E., Hocking, L. J., Hofman, A., Homuth, G., Hooning, M. J., Hopper, J. L., Hu, F. B., Huang, J., Humphreys, K., Hunter, D. J., Jakubowska, A., Jones, S. E., Kabisch, M., Karasik, D., Knight, J. A., Kolcic, I., Kooperberg, C., Kosma, V. M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X., Lindström, S., Liu, Y., Luan, JA., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N. G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R. L., Müller-Nurasyid, M., Nalls, M., Neale, B. M., Nevanlinna, H., Neven, P., Newman, A. B., Nordestgaard, B. G., Olson, J. E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P. D. P., Pirastu, N. N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B. M., Pylkäs, K., Radice, P., Raffel, L. J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C. F., Sanna, S., Sawyer, E. J., Schlessinger, D., Schmidt, M. K., Schmidt, F., Schmutzler, R. K., Schoemaker, M. J., Scott, R. A., Seynaeve, C. M., Simard, J., Sorice, R., Southey, M. C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K. D., Thorsteinsdottir, U., Toland, A. E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S. T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J. F., Winqvist, R., Wolffenbuttel, B. B. H. R., Wright, A. F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D. I., Buring, J. E., Ferrucci, L., Montgomery, G. W., Gudnason, V., Spector, T. D., Van Duijn, C. M., Alizadeh, B. Z., Ciullo, M., Crisponi, L., Easton, D. F., Gasparini, P. P., Gieger, C., Harris, T. B., Hayward, C., Kardia, S. L. R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A. C., Reiner, A. P., Ridker, P. M., Rotter, J. I., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Völzke, H., Wareham, N. J., Weir, D. R., Yerges-Armstrong, L. M., Price, A. L., Stefansson, K., Visser, J. A., Ong, K. K., Chang-Claude, J., Murabito, J. M., Perry, J. R. B. & Murray, A., Dec 1 2015, In : Obstetrical and Gynecological Survey. 70, 12, p. 758-762 5 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Day, F. R., Ruth, K. S., Thompson, D. J., Lunetta, K. L., Pervjakova, N., Chasman, D. I., Stolk, L., Finucane, H. K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A. D., Elks, C. E., Franceschini, N., He, C., Altmaier, E., Brody, J. A., Franke, L. L., EHuffman, J., Keller, M. F. & 221 others, McArdle, P. F., Nutile, T., Porcu, E., Robino, A., Rose, L. M., Schick, U. M., Smith, J. A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J. J., Mangino, M., Smith, A. V., Tanaka, T., Abecasis, G. R., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C., Arndt, V., Arnold, A. M., Barbieri, C., Beckmann, M. W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S. J., Blomqvist, C., Boerwinkle, E., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Borresen-Dale, A. L., Boutin, T. S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S. J., Chapman, J. R., Chen, Y. D. I., Chenevix-Trench, G., Couch, F. J., Coviello, A. D., Cox, A., Czene, K., Darabi, H., De Vivo, I., Demerath, E. W., Dennis, J., Devilee, P., Dörk, T., Dos-Santos-Silva, I., Dunning, A. M., Eicher, J. D., Fasching, P. A., Faul, J. D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M. E., García-Closas, M., Giles, G. G., Girotto, G. G., Goldberg, M. S., Gonz'lez-Neira, A., Goodarzi, M. O., Grove, M. L., Gudbjartsson, D. F., Guénel, P., Guo, X., Haiman, C. A., Hall, P., Hamann, U., Henderson, B. E., Hocking, L. J., Hofman, A., Homuth, G., Hooning, M. J., Hopper, J. L., Hu, F. B., Huang, J., Humphreys, K., Hunter, D. J., Jakubowska, A., Jones, S. E., Kabisch, M., Karasik, D., Knight, J. A., Kolcic, I., Kooperberg, C., Kosma, V. M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X., Lindström, S., Liu, Y., Luan, JA., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N. G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R. L., Müller-Nurasyid, M., Nalls, M., Neale, B. M., Nevanlinna, H., Neven, P., Newman, A. B., Nordestgaard, BØ. G., Olson, J. E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P. D. P., Pirastu, N. N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B. M., Pylkäs, K., Radice, P., Raffel, L. J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C. F., Sanna, S., Sawyer, E. J., Schlessinger, D., Schmidt, M. K., Schmidt, F., Schmutzler, R. K., Schoemaker, M. J., Scott, R. A., Seynaeve, C. M., Simard, J., Sorice, R., Southey, M. C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K. D., Thorsteinsdottir, U., Toland, A. E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S. T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J. F., Winqvist, R., Wolffenbuttel, B. B. H. R., Wright, A. F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D. I., Buring, J. E., Ferrucci, L., Montgomery, G. W., Gudnason, V., Spector, T. D., Duijn, C. M., Alizadeh, B. Z., Ciullo, M., Crisponi, L., Easton, D. F., Gasparini, P. P., Gieger, C., Harris, T. B., Hayward, C., Kardia, S. L. R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A. C., Reiner, A. P., Ridker, P. M., Rotter, J. I., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Völzke, H., Wareham, N. J., Weir, D. R., Yerges-Armstrong, L. M., Price, A. L., Stefansson, K., Visser, J. A., Ong, K. K., Chang-Claude, J., Murabito, J. M., Perry, J. R. B. & Murray, A., Nov 1 2015, In : Nature Genetics. 47, 11, p. 1294-1303 10 p.

Research output: Contribution to journalArticle

Menopause
DNA Repair
Breast Neoplasms
Mendelian Randomization Analysis
DNA Damage
7 Citations (Scopus)

Multi-ethnic analysis reveals soluble l-selectin may be post-transcriptionally regulated by 3′UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA)

Berardi, C., Larson, N., Decker, P. A., Wassel, C. L., Kirsch, P. S., Pankow, J. S., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Tsai, M. Y., Chen, Y. D. I. & Bielinski, S. J., 2015, In : Human Genetics. 134, 4, p. 393-403 11 p.

Research output: Contribution to journalArticle

Selectins
Atherosclerosis
Linear Models
Cardiovascular Diseases
African Americans
26 Citations (Scopus)

P-selectin and subclinical and clinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bielinski, S. J., Berardi, C., Decker, P. A., Kirsch, P. S., Larson, N., Pankow, J. S., Sale, M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Wassel, C. L., Polak, J. F. & Tsai, M. Y., May 1 2015, In : Atherosclerosis. 240, 1, p. 3-9 7 p.

Research output: Contribution to journalArticle

P-Selectin
Atherosclerosis
Coronary Disease
Coronary Vessels
Calcium
9 Citations (Scopus)
Depression
Quality of Life
Health
Logistic Models
Health Fairs
9 Citations (Scopus)

Soluble P-selectin predicts lower extremity peripheral artery disease incidence and change in the ankle brachial index: The Multi-Ethnic Study of Atherosclerosis (MESA)

Wassel, C. L., Berardi, C., Pankow, J. S., Larson, N., Decker, P. A., Hanson, N. Q., Tsai, M. Y., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2015, In : Atherosclerosis. 239, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
P-Selectin
Peripheral Arterial Disease
Lower Extremity
Atherosclerosis