• 41833 Citations
  • 104 Scopus h-Index
1980 …2020

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Article
2011

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men

Mödder, U. I., Hoey, K. A., Amin, S., McCready, L. K., Achenbach, S. J., Riggs, B. L., Melton, L. J. & Khosla, S., Feb 2011, In : Journal of Bone and Mineral Research. 26, 2, p. 373-379 7 p.

Research output: Contribution to journalArticle

251 Scopus citations

Relationship of testosterone and osteocalcin levels during growth

Kirmani, S., Atkinson, E. J., Melton, L. J., Riggs, B. L., Amin, S. & Khosla, S., Sep 2011, In : Journal of Bone and Mineral Research. 26, 9, p. 2212-2216 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip

Dragomir-Daescu, D., Op Den Buijs, J., McEligot, S., Dai, Y., Entwistle, R. C., Salas, C., Melton, L. J., Bennet, K. E., Khosla, S. & Amin, S., Feb 2011, In : Annals of Biomedical Engineering. 39, 2, p. 742-755 14 p.

Research output: Contribution to journalArticle

151 Scopus citations

The bone and beyond: A shift in calcium

Khosla, S., Apr 1 2011, In : Nature Medicine. 17, 4, p. 430-431 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors

Nelson, E. R., DuSell, C. D., Wang, X., Howe, M. K., Evans, G., Michalek, R. D., Umetani, M., Rathmell, J. C., Khosla, S., Gesty-Palmer, D. & McDonnell, D. P., Dec 2011, In : Endocrinology. 152, 12, p. 4691-4705 15 p.

Research output: Contribution to journalArticle

63 Scopus citations

Towards a diagnostic and therapeutic consensus in male osteoporosis

Kanis, J. A., Bianchi, G., Bilezikian, J. P., Kaufman, J. M., Khosla, S., Orwoll, E. & Seeman, E., Nov 2011, In : Osteoporosis International. 22, 11, p. 2789-2798 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Trabecular bone deficits among Vietnamese immigrants

Melton, L. J., Marquez, M. A., McCready, L. K., Achenbach, S. J., Riggs, B. L., Amin, S. & Khosla, S., May 2011, In : Osteoporosis International. 22, 5, p. 1627-1631 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Wnt10b activates the wnt, notch, and NFIκB pathways in u2os osteosarcoma cells

Mödder, U. I., Oursler, M. J., Khosla, S. & Monroe, D. G., May 2011, In : Journal of cellular biochemistry. 112, 5, p. 1392-1402 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2010

Age-dependence of femoral strength in white women and men

Keaveny, T. M., Kopperdahl, D. L., Melton, L. J., Hoffmann, P. F., Amin, S., Riggs, B. L. & Khosla, S., May 1 2010, In : Journal of Bone and Mineral Research. 25, 5, p. 994-1001 8 p.

Research output: Contribution to journalArticle

115 Scopus citations

Assessing forearm fracture risk in postmenopausal women

Melton, L. J., Christen, D., Riggs, B. L., Achenbach, S. J., Müller, R., Van Lenthe, G. H., Amin, S., Atkinson, E. J. & Khosla, S., Jul 2010, In : Osteoporosis International. 21, 7, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Undale, A., Srinivasan, B., Drake, M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Moedder, U. I. & Khosla, S., Jul 2010, In : Bone. 47, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells

Gössl, M., Mödder, U. I., Gulati, R., Rihal, C. S., Prasad, A., Loeffler, D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 2010, In : European heart journal. 31, 23, p. 2909-2914 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Effects of chronic estrogen treatment on modulating age-related bone loss in female mice

Syed, F. A., Mödder, U. I., Roforth, M., Hensen, I., Fraser, D. G., Peterson, J. M., Oursler, M. J. & Khosla, S., Nov 2010, In : Journal of Bone and Mineral Research. 25, 11, p. 2438-2446 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effects of estrogen and testosterone on resting energy expenditure in older men

Santosa, S., Khosla, S., McCready, L. K. & Jensen, M. D., Dec 2010, In : Obesity. 18, 12, p. 2392-2394 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

Drake, M. T., Srinivasan, B., Mödder, U. I., Peterson, J. M., McCready, L. K., Riggs, B. L., Dwyer, D., Stolina, M., Kostenuik, P. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5056-5062 7 p.

Research output: Contribution to journalArticle

198 Scopus citations

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. T., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5063-5068 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells

Kopher, R. A., Penchev, V. R., Islam, M. S., Hill, K. L., Khosla, S. & Kaufman, D. S., Oct 2010, In : Bone. 47, 4, p. 718-728 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Modulators of androgen and estrogen receptor activity

Clarke, B. L. & Khosla, S., Jan 1 2010, In : Critical Reviews in Eukaryotic Gene Expression. 20, 4, p. 275-294 20 p.

Research output: Contribution to journalArticle

7 Scopus citations

Relation of serum serotonin levels to bone density and structural parameters in women

Mödder, U. I., Achenbach, S. J., Amin, S., Riggs, B. L., Melton, L. J. & Khosla, S., Feb 2010, In : Journal of Bone and Mineral Research. 25, 2, p. 415-422 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

Relation of vertebral deformities to bone density, structure, and strength

Melton, L. J., Riggs, B. L., Keaveny, T. M., Achenbach, S. J., Kopperdahl, D., Camp, J. J., Rouleau, P. A., Amin, S., Atkinson, E. J., Robb, R. A., Therneau, T. M. & Khosla, S., Sep 2010, In : Journal of Bone and Mineral Research. 25, 9, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis

DuSell, C. D., Nelson, E. R., Wang, X., Abdo, J., Mödder, U. I., Umetani, M., Gesty-Palmer, D., Javitt, N. B., Khosla, S. & McDonnell, D. P., Aug 2010, In : Endocrinology. 151, 8, p. 3675-3685 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Update in male osteoporosis

Khosla, S., Jan 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

122 Scopus citations
2009

Androgens and bone

Clarke, B. L. & Khosla, S., Mar 2009, In : Steroids. 74, 3, p. 296-305 10 p.

Research output: Contribution to journalArticle

121 Scopus citations

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

184 Scopus citations

Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo

Clowes, J. A., Eghbali-Fatourechi, G. Z., McCready, L., Oursler, M. J., Khosla, S. & Riggs, B. L., May 2009, In : Osteoporosis International. 20, 5, p. 761-769 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
74 Scopus citations

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements

Henderson, G. C., Dhatariya, K., Ford, G. C., Klaus, K. A., Basu, R., Rizza, R. A., Jensen, M. D., Khosla, S., O'Brien, P. & Nair, K. S., Feb 2009, In : FASEB Journal. 23, 2, p. 631-641 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2

Mödder, U. I., Monroe, D. G., Fraser, D. G., Spelsberg, T. C., Rosen, C. J., Géhin, M., Chambon, P., O'Malley, B. W. & Khosla, S., Jul 10 2009, In : Journal of Biological Chemistry. 284, 28, p. 18767-18777 11 p.

Research output: Contribution to journalArticle

22 Scopus citations
2008

Abdominal aortic calcification, BMD, and bone microstructure: A population-based study

Chow, J. T., Khosla, S., Melton, L. J., Atkinson, E. J., Camp, J. J. & Kearns, A. E., Oct 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1601-1612 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

A bone structural basis for fracture risk in diabetes

Melton, L. J., Riggs, B. L., Leibson, C. L., Achenbach, S. J., Camp, J. J., Bouxsein, M. L., Atkinson, E. J., Robb, R. A. & Khosla, S., Dec 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 12, p. 4804-4809 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., McDaniel, L., Amin, S., Rouleau, P. A. & Khosla, S., Feb 2008, In : Journal of Bone and Mineral Research. 23, 2, p. 205-214 10 p.

Research output: Contribution to journalArticle

343 Scopus citations

Bone growth and turnover in progesterone receptor knockout mice

Rickard, D. J., Iwaniec, U. T., Evans, G., Hefferan, T. E., Hunter, J. C., Waters, K. M., Lydon, J. P., O'Malley, B. W., Khosla, S., Spelsberg, T. C. & Turner, R. T., May 2008, In : Endocrinology. 149, 5, p. 2383-2390 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

152 Scopus citations
56 Scopus citations

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 2008, In : Osteoporosis International. 19, 4, p. 437-447 11 p.

Research output: Contribution to journalArticle

330 Scopus citations

Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women

Syed, F. A., Oursler, M. J., Hefferanm, T. E., Peterson, J. M., Riggs, B. L. & Khosla, S., Sep 2008, In : Osteoporosis International. 19, 9, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

122 Scopus citations
38 Scopus citations

Fracture risk in type 2 diabetes: Update of a population-based study

Melton, L. J., Leibson, C. L., Achenbach, S. J., Therneau, T. M. & Khosla, S., Aug 2008, In : Journal of Bone and Mineral Research. 23, 8, p. 1334-1342 9 p.

Research output: Contribution to journalArticle

237 Scopus citations

Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA

Dawson-Hughes, B., Tosteson, A. N. A., Melton, L. J., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 1 2008, In : Osteoporosis International. 19, 4, p. 449-458 10 p.

Research output: Contribution to journalArticle

312 Scopus citations

Loss of ERE binding activity by estrogen receptor-α alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells

Rudnik, V., Sanyal, A., Syed, F. A., Monroe, D. G., Spelsberg, T. C., Oursler, M. J. & Khosla, S., Feb 15 2008, In : Journal of cellular biochemistry. 103, 3, p. 896-907 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Osteocalcin Expression by Circulating Endothelial Progenitor Cells in Patients With Coronary Atherosclerosis

Gössl, M., Mödder, U. I., Atkinson, E. J., Lerman, A. & Khosla, S., Oct 14 2008, In : Journal of the American College of Cardiology. 52, 16, p. 1314-1325 12 p.

Research output: Contribution to journalArticle

121 Scopus citations
331 Scopus citations

Regulation of bone turnover by sex steroids in men

Sanyal, A., Hoey, K. A., Mödder, U. I., Lamsam, J. L., McCready, L. K., Peterson, J. M., Achenbach, S. J., Oursler, M. J. & Khosla, S., May 2008, In : Journal of Bone and Mineral Research. 23, 5, p. 705-714 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Serum biomarker profile associated with high bone turnover and BMD in postmenopausal women

Bhattacharyya, S., Siegel, E. R., Achenbach, S. J., Khosla, S. & Suva, L. J., Jul 2008, In : Journal of Bone and Mineral Research. 23, 7, p. 1106-1117 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
52 Scopus citations

The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice

Mödder, U. I., Sanyal, A., Xu, J., O'Malley, B. W., Spelsberg, T. C. & Khosla, S., Feb 2008, In : Bone. 42, 2, p. 414-421 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Use of renal function measurements for assessing fracture risk in postmenopausal women

McCarthy, J. T., Rule, A. D., Achenbach, S. J., Bergstralh, E. J., Khosla, S. & Melton, L. J., Nov 2008, In : Mayo Clinic proceedings. 83, 11, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2007

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

114 Scopus citations

Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women

Melton, L. J., Riggs, B. L., Van Lenthe, G. H., Achenbach, S. J., Müller, R., Bouxsein, M. L., Amin, S., Atkinson, E. J. & Khosla, S., Sep 2007, In : Journal of Bone and Mineral Research. 22, 9, p. 1442-1448 7 p.

Research output: Contribution to journalArticle

149 Scopus citations