• 39787 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

Bone marrow stromal cells express two distinct splice variants of ER-α that are regulated by estrogen

Sanyal, A., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Jan 1 2005, In : Journal of Cellular Biochemistry. 94, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes

Klingberg, E., Lorentzon, M., Göthlin, J., Mellström, D., Geijer, M., Ohlsson, C., Atkinson, E. J., Khosla, S., Carlsten, H. & Forsblad-d'Elia, H., Nov 5 2013, In : Arthritis Research and Therapy. 15, 6, R179.

Research output: Contribution to journalArticle

46 Scopus citations

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS

Ng, A. C., Khosla, S., Charatcharoenwitthaya, N., Kumar, S. K., Achenbach, S. J., Holets, M. F., McCready, L. K., Melton, L. J., Kyle, R. A., Rajkumar, S. V. & Drake, M. M., Dec 15 2011, In : Blood. 118, 25, p. 6529-6534 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Bone quality in type 2 diabetes mellitus

Farr, J. & Khosla, S., Jan 1 2016, Diabetic Bone Disease: Basic and Translational Research and Clinical Applications. Springer International Publishing, p. 211-224 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

Farr, J., Amin, S., Melton, L. J., Kirmani, S., McCready, L. K., Atkinson, E. J., Müller, R. & Khosla, S., Mar 2014, In : Journal of Bone and Mineral Research. 29, 3, p. 590-599 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

177 Scopus citations

Bone-targeted replacement therapy for hypophosphatasia

Drake, M. M. & Khosla, S., Jun 2008, In : Journal of Bone and Mineral Research. 23, 6, p. 775-776 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Bone turnover across the menopause transition: Correlations with inhibins and follicle-stimulating hormone

Perrien, D. S., Achenbach, S. J., Bledsoe, S. E., Walser, B., Suva, L. J., Khosla, S. & Gaddy, D., May 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Building bone to reverse osteoporosis and repair fractures

Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

273 Scopus citations

Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Firek, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

150 Scopus citations

Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation?

Binkley, N., Lappe, J., Singh, R. J., Khosla, S., Krueger, D., Drezner, M. K. & Blank, R. D., May 1 2015, In : Osteoporosis International. 26, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned

Drake, M. M., Clarke, B., Oursler, M. J. & Khosla, S., Aug 1 2017, In : Endocrine Reviews. 38, 4, p. 325-350 26 p.

Research output: Contribution to journalReview article

44 Scopus citations

Cellular senescence in bone

Farr, J. & Khosla, S., Apr 1 2019, In : Bone. 121, p. 121-133 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

Shui, C., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Feb 1 2003, In : Journal of Bone and Mineral Research. 18, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

175 Scopus citations

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection

Mödder, U. I., Roforth, M. M., Nicks, K. M., Peterson, J. M., McCready, L. K., Monroe, D. G. & Khosla, S., Mar 2012, In : Bone. 50, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Circulating cells with osteogenic potential

Khosla, S. & Eghbali-Fatourechi, G. Z., Apr 2006, In : Annals of the New York Academy of Sciences. 1068, 1, p. 489-497 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., Sep 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women

McKane, W. R., Khosla, S., Peterson, J. M., Egan, K. & Riggs, B. L., Aug 1994, In : Journal of Bone and Mineral Research. 9, 8, p. 1313-1318 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Circulating osteoblast-lineage cells [4] (multiple letters)

Sata, M., Tanaka, K., Nagai, R., Eghbali-Fatourechi, G. Z. & Khosla, S., Aug 18 2005, In : New England Journal of Medicine. 353, 7, p. 737-738 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Circulating osteoblast-lineage cells in humans

Eghbali-Fatourechi, G. Z., Lamsam, J., Fraser, D., Nagel, D., Riggs, B. L. & Khosla, S., May 12 2005, In : New England Journal of Medicine. 352, 19, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

289 Scopus citations

Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Moedder, U. I. & Khosla, S., Jul 2010, In : Bone. 47, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease

Yang, S. W., Hennessy, R. R., Khosla, S., Lennon, R., Loeffler, D., Sun, T., Liu, Z., Park, K. H., Wang, F. L., Lerman, L. O. & Lerman, A., Jan 15 2017, In : International Journal of Cardiology. 227, p. 833-839 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

Al-Hijji, M., Narula, N., Go, J. L., Khosla, S., Sarano, M. E., Loeffler, D., Lennon, R., Lerman, L. O. & Lerman, A., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium

Barron, M. L., Rybchyn, M. S., Ramesh, S., Mason, R. S., Fiona Bonar, S., Stalley, P., Khosla, S., Hudson, B., Arthur, C., Kim, E., Clifton-Bligh, R. J. & Clifton-Bligh, P. B., Mar 14 2017, In : Bone Research. 5, 16057.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical performance of parathyroid hormone immunometric assays

Kao, P. C., Van Heerden, J. A., Grant, C. S., Klee, G. G. & Khosla, S., 1992, In : Mayo Clinic Proceedings. 67, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Clinical practice guideline: Androgen therapy in women: An Endocrine Society clinical practice guideline

Wierman, M. E., Basson, R., Davis, S. R., Khosla, S., Miller, K. K., Rosner, W. & Santoro, N., Oct 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 10, p. 3697-3710 14 p.

Research output: Contribution to journalArticle

241 Scopus citations

Clinical review 144: Estrogen and the male skeleton

Khosla, S., Joseph Melton, L. & Lawrence Riggs, B., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 4, p. 1443-1450 8 p.

Research output: Contribution to journalArticle

247 Scopus citations

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I

Engelke, K., Lang, T., Khosla, S., Qin, L., Zysset, P., Leslie, W. D., Shepherd, J. A. & Schousboe, J. T., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 338-358 21 p.

Research output: Contribution to journalArticle

39 Scopus citations

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III

Engelke, K., Lang, T., Khosla, S., Qin, L., Zysset, P., Leslie, W. D., Shepherd, J. A. & Shousboe, J. T., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 393-407 15 p.

Research output: Contribution to journalArticle

46 Scopus citations

Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II

Zysset, P., Qin, L., Lang, T., Khosla, S., Leslie, W. D., Shepherd, J. A., Schousboe, J. T. & Engelke, K., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 359-392 34 p.

Research output: Contribution to journalArticle

58 Scopus citations
56 Scopus citations

Comprehensive assessment of osteoporosis and bone fragility with ct colonography

Fidler, J. L., Murthy, N. S., Khosla, S., Clarke, B., Bruining, D. H., Kopperdahl, D. L., Lee, D. C. & Keaveny, T. M., Jan 1 2016, In : Radiology. 278, 1, p. 172-180 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair

Khosla, S., Westendorf, J. J. & Mödder, U. I., Dec 2010, In : Stem Cells. 28, 12, p. 2124-2128 5 p.

Research output: Contribution to journalArticle

63 Scopus citations

Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women

Melton, L. J., Riggs, B. L., Van Lenthe, G. H., Achenbach, S. J., Müller, R., Bouxsein, M. L., Amin, S., Atkinson, E. J. & Khosla, S., Sep 2007, In : Journal of Bone and Mineral Research. 22, 9, p. 1442-1448 7 p.

Research output: Contribution to journalArticle

147 Scopus citations
87 Scopus citations

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells

Gössl, M., Mödder, U. I., Gulati, R., Rihal, C., Prasad, A., Loeffler, D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 2010, In : European Heart Journal. 31, 23, p. 2909-2914 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women

Prasad, M., Reriani, M., Khosla, S., Gössl, M., Lennon, R., Gulati, R., Prasad, A., Lerman, L. O. & Lerman, A., 2014, In : Vascular Health and Risk Management. 10, p. 533-538 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Correlates of osteoprotegerin levels in women and men

Khosla, S., Arrighi, H. M., Melton, L. J., Atkinson, E. J., O'Fallon, W. M., Dunstan, C. & Riggs, B. L., 2002, In : Osteoporosis International. 13, 5, p. 394-399 6 p.

Research output: Contribution to journalArticle

163 Scopus citations

Corrigendum to "Characterization of circulating osteoblast lineage cells in humans" [Bone 40 (2007) 1370-1377] (DOI: 10.1016/j.bone.2006.12.064)

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., Oct 2007, In : Bone. 41, 4, p. 741 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Modder, U. I. & Khosla, S., Mar 1 2011, In : Bone. 48, 3, p. 671 1 p.

Research output: Contribution to journalArticle

Corrigendum to "Letter to the Editor" [Bone 38 (2006) 289]

Khosla, S., Modder, U. I. & Syed, F. A., Mar 1 2011, In : Bone. 48, 3, p. 670 1 p.

Research output: Contribution to journalArticle

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study

Samelson, E. J., Broe, K. E., Xu, H., Yang, L., Boyd, S., Biver, E., Szulc, P., Adachi, J., Amin, S., Atkinson, E., Berger, C., Burt, L., Chapurlat, R., Chevalley, T., Ferrari, S., Goltzman, D., Hanley, D. A., Hannan, M. T., Khosla, S., Liu, C. T. & 13 others, Lorentzon, M., Mellstrom, D., Merle, B., Nethander, M., Rizzoli, R., Sornay-Rendu, E., Van Rietbergen, B., Sundh, D., Wong, A. K. O., Ohlsson, C., Demissie, S., Kiel, D. P. & Bouxsein, M. L., Jan 1 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Cortical porosity identifies women with osteopenia at increased risk for forearm fractures

Bala, Y., Zebaze, R., Ghasem-Zadeh, A., Atkinson, E. J., Iuliano, S., Peterson, J. M., Amin, S., Bjørnerem, Å., Melton, L. J., Johansson, H., Kanis, J. A., Khosla, S. & Seeman, E., 2014, In : Journal of Bone and Mineral Research. 29, 6, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

99 Scopus citations

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Bairn, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Aug 2008, In : Obstetrical and Gynecological Survey. 63, 8, p. 516-517 2 p.

Research output: Contribution to journalArticle

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 2008, In : Osteoporosis International. 19, 4, p. 437-447 11 p.

Research output: Contribution to journalArticle

320 Scopus citations

Cross-sectional versus longitudinal evaluation of bone loss in men and women

Melton, L. J., Khosla, S., Atkinson, E. J., O'Connor, M. K., O'Fallon, W. M. & Riggs, B. L., 2000, In : Osteoporosis International. 11, 7, p. 592-599 8 p.

Research output: Contribution to journalArticle

94 Scopus citations

Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women

Kassem, M., Khosla, S., Spelsberg, T. C. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 2, p. 513-518 6 p.

Research output: Contribution to journalArticle

58 Scopus citations