• 40590 Citations
  • 102 Scopus h-Index
1976 …2021

Research output per year

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Research Output

Article

Is vitamin D a determinant of muscle mass and strength?

Marantes, I., Achenbach, S. J., Atkinson, E. J., Khosla, S., Melton, L. J. & Amin, S., Dec 1 2011, In : Journal of Bone and Mineral Research. 26, 12, p. 2860-2871 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis

Jafari, A., Qanie, D., Andersen, T. L., Zhang, Y., Chen, L., Postert, B., Parsons, S., Ditzel, N., Khosla, S., Johansen, H. T., Kjærsgaard-Andersen, P., Delaisse, J. M., Abdallah, B. M., Hesselson, D., Solberg, R. & Kassem, M., Feb 14 2017, In : Stem Cell Reports. 8, 2, p. 373-386 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes

Thomas, T., Gori, F., Khosla, S., Jensen, M. D., Burguera, B. & Riggs, B. L., Jan 1 1999, In : Endocrinology. 140, 4, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

Open Access
597 Scopus citations

Leptin reduces ovariectomy-induced bone loss in rats

Burguera, B., Hofbauer, L. C., Thomas, T., Gori, F., Evans, G. L., Khosla, S., Riggs, B. L. & Turner, R. T., Jan 1 2001, In : Endocrinology. 142, 8, p. 3546-3553 8 p.

Research output: Contribution to journalArticle

Open Access
248 Scopus citations

Longitudinal changes in lumbar bone mineral density distribution may increase the risk of wedge fractures

Giambini, H., Khosla, S., Nassr, A., Zhao, C. & An, K. N., Jan 1 2013, In : Clinical Biomechanics. 28, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Loss of ERE binding activity by estrogen receptor-α alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells

Rudnik, V., Sanyal, A., Syed, F. A., Monroe, D. G., Spelsberg, T. C., Oursler, M. J. & Khosla, S., Feb 15 2008, In : Journal of cellular biochemistry. 103, 3, p. 896-907 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas

Khosla, S., Patel, V. M., Hay, I. D., Schaid, D. J., Grant, C. S., Van Heerden, J. A. & Thibodeau, S. N., Jan 1 1991, In : Journal of Clinical Investigation. 87, 5, p. 1691-1699 9 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations

LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis

Aquino-Martinez, R., Rowsey, J. L., Fraser, D. G., Eckhardt, B. A., Khosla, S., Farr, J. N. & Monroe, D. G., Mar 2020, In : Bone. 132, 115220.

Research output: Contribution to journalArticle

Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength

Robinson, J. W., Blixt, N. C., Norton, A., Mansky, K. C., Ye, Z., Aparicio, C., Wagner, B. M., Benton, A. M., Warren, G. L., Khosla, S., Gaddy, D., Suva, L. J. & Potter, L. R., Jun 2020, In : Bone. 135, 115320.

Research output: Contribution to journalArticle

Measurement of gene expression following cryogenic μ-CT scanning of human iliac crest biopsies

Maran, A., Khosla, S., Riggs, B. L., Zhang, M., Ritman, E. L. & Turner, R. T., Mar 1 2003, In : Journal of Musculoskeletal Neuronal Interactions. 3, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study

McKane, W. R., Khosla, S., Burritt, M. F., Kao, P. C., Wilson, D. M., Ory, S. J. & Riggs, B. L., Dec 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 12, p. 3458-3464 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone

Locklin, R. M., Khosla, S., Turner, R. T. & Riggs, B. L., May 1 2003, In : Journal of cellular biochemistry. 89, 1, p. 180-190 11 p.

Research output: Contribution to journalArticle

165 Scopus citations

Microarchitecture and Peripheral BMD are Impaired in Postmenopausal White Women with Fracture Independently of Total Hip T-Score: An International Multicenter Study

Boutroy, S., Khosla, S., Sornay-Rendu, E., Zanchetta, M. B., McMahon, D. J., Zhang, C. A., Chapurlat, R. D., Zanchetta, J., Stein, E. M., Bogado, C., Majumdar, S., Burghardt, A. J. & Shane, E., Jun 1 2016, In : Journal of Bone and Mineral Research. 31, 6, p. 1158-1166 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

miR-219a-5p Regulates Rorβ During Osteoblast Differentiation and in Age-related Bone Loss

Aquino-Martinez, R., Farr, J. N., Weivoda, M. M., Negley, B. A., Onken, J. L., Thicke, B. S., Fulcer, M. M., Fraser, D. G., van Wijnen, A. J., Khosla, S. & Monroe, D. G., Jan 2019, In : Journal of Bone and Mineral Research. 34, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Modulators of androgen and estrogen receptor activity

Clarke, B. L. & Khosla, S., Jan 1 2010, In : Critical Reviews in Eukaryotic Gene Expression. 20, 4, p. 275-294 20 p.

Research output: Contribution to journalArticle

7 Scopus citations

Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography

Burghardt, A. J., Pialat, J. B., Kazakia, G. J., Boutroy, S., Engelke, K., Patsch, J. M., Valentinitsch, A., Liu, D., Szabo, E., Bogado, C. E., Zanchetta, M. B., McKay, H. A., Shane, E., Boyd, S. K., Bouxsein, M. L., Chapurlat, R., Khosla, S. & Majumdar, S., Mar 1 2013, In : Journal of Bone and Mineral Research. 28, 3, p. 524-536 13 p.

Research output: Contribution to journalArticle

75 Scopus citations

Muscle strength in Osteoporotic versus normal women

Sinaki, M., Khosla, S., Limburg, P. J., Rogers, J. W. & Murtaugh, P. A., Jan 1 1993, In : Osteoporosis International. 3, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

72 Scopus citations

Mutations in the RET protooncogene in sporadic pheochromocytomas

Lindor, N. M., Honchel, R., Khosla, S. & Thibodeau, S. N., Feb 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 2, p. 627-629 3 p.

Research output: Contribution to journalArticle

61 Scopus citations

Mutual antagonism of estrogen receptors α and β and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines

Monroe, D. G., Johnsen, S. A., Subramaniam, M., Getz, B. J., Khosla, S., Riggs, B. L. & Spelsberg, T. C., Mar 1 2003, In : Journal of Endocrinology. 176, 3, p. 349-357 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact

Fujita, K., Xing, Q., Khosla, S. & Monroe, D. G., Nov 1 2014, In : Journal of Cellular Biochemistry. 115, 11, p. 2039-2044 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
39 Scopus citations

Native osteoprotegerin gene transfer inhibits the development of murine osteolytic bone disease induced by tumor xenografts

Doran, P. M., Turner, R. T., Chen, D., Facteau, S. M., Ludvigson, J. M., Khosla, S., Riggs, B. L. & Russell, S. J., Apr 1 2004, In : Experimental Hematology. 32, 4, p. 351-359 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Net ankle quasi-stiffness is influenced by walking speed but not age for older adult women

Collins, J. D., Arch, E. S., Crenshaw, J. R., Bernhardt, K. A., Khosla, S., Amin, S. & Kaufman, K. R., May 1 2018, In : Gait and Posture. 62, p. 311-316 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

New hope for symptom management during natural and iatrogenic menopause transitions

Woodruff, T. K. & Khosla, S., Aug 1 2017, In : Biology of Reproduction. 97, 2, p. 177-178 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

New Insights into Androgen and Estrogen Receptor Regulation of the Male Skeleton

Khosla, S., Jul 1 2015, In : Journal of Bone and Mineral Research. 30, 7, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Nonoxidative free fatty acid disposal is greater in young women than men

Koutsari, C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Feb 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 541-547 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism

Indridason, O. S., Heath, H., Khosla, S., Yohay, D. A. & Quarles, L. D., Nov 1996, In : Kidney international. 50, 5, p. 1663-1671 9 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Novel anthropomorphic hip phantom corrects systemic interscanner differences in proximal femoral vBMD

Bonaretti, S., Carpenter, R. D., Saeed, I., Burghardt, A. J., Yu, L., Bruesewitz, M., Khosla, S. & Lang, T., Dec 21 2014, In : Physics in medicine and biology. 59, 24, p. 7819-7834 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Nucleotide sequence of cloned cDNAs encoding chicken preproparathyroid hormone

Khosla, S., Demay, M., Pines, M., Hurwitz, S., Potts, J. T. & Kronenberg, H. M., Dec 1988, In : Journal of Bone and Mineral Research. 3, 6, p. 689-698 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training

Bonaretti, S., Vilayphiou, N., Chan, C. M., Yu, A., Nishiyama, K., Liu, D., Boutroy, S., Ghasem-Zadeh, A., Boyd, S. K., Chapurlat, R., McKay, H., Shane, E., Bouxsein, M. L., Black, D. M., Majumdar, S., Orwoll, E. S., Lang, T. F., Khosla, S. & Burghardt, A. J., Jul 30 2016, (Accepted/In press) In : Osteoporosis International. p. 1-13 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Osteocalcin Expression by Circulating Endothelial Progenitor Cells in Patients With Coronary Atherosclerosis

Gössl, M., Mödder, U. I., Atkinson, E. J., Lerman, A. & Khosla, S., Oct 14 2008, In : Journal of the American College of Cardiology. 52, 16, p. 1314-1325 12 p.

Research output: Contribution to journalArticle

118 Scopus citations

Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis

Flammer, A. J., Gössl, M., Widmer, R. J., Reriani, M., Lennon, R., Loeffler, D., Shonyo, S., Simari, R. D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 1 2012, In : European heart journal. 33, 23, p. 2963-2969 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Weivoda, M., Ruan, M., Pederson, L., Hachfeld, C., Davey, R. A., Zajac, J. D., Westendorf, J. J., Khosla, S. & Oursler, M. J., 2015, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

28 Scopus citations

Osteogenic monocytes within the coronary circulation and their association with plaque vulnerability in patients with early atherosclerosis

Collin, J., Gössl, M., Matsuo, Y., Cilluffo, R. R., Flammer, A. J., Loeffler, D., Lennon, R. J., Simari, R. D., Spoon, D. B., Erbel, R., Lerman, L. O., Khosla, S. & Lerman, A., Feb 15 2015, In : International Journal of Cardiology. 181, p. 57-64 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Osteopenia

Khosla, S. & Melton, L. J., May 31 2007, In : New England Journal of Medicine. 356, 22, p. 2293-2300 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Osteopenia in adults with a history of juvenile rheumatoid arthritis. A population based study

French, A. R., Mason, T., Nelson, A. M., Crowson, C. S., O'Fallon, W. M., Khosla, S. & Gabriel, S. E., May 20 2002, In : Journal of Rheumatology. 29, 5, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Osteoporosis: Gender differences and similarities

Khosla, S., Melton, L. J. & Riggs, B. L., Jan 1 1999, In : Lupus. 8, 5, p. 393-396 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS)

Adams, A. L., Fischer, H., Kopperdahl, D. L., Lee, D. C., Black, D. M., Bouxsein, M. L., Fatemi, S., Khosla, S., Orwoll, E. S., Siris, E. S. & Keaveny, T. M., Jul 2018, In : Journal of Bone and Mineral Research. 33, 7, p. 1291-1301 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Osteoporosis assessment by whole body region vs. site-specific DXA

Melton, L. J., Looker, A. C., Shepherd, J. A., O'Connor, M. K., Achenbach, S. J., Riggs, B. L. & Khosla, S., Dec 1 2005, In : Osteoporosis International. 16, 12, p. 1558-1564 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Osteoporosis detection in postmenopausal women using axial transmission multi-frequency bone ultrasonometer: Clinical findings

Egorov, V., Tatarinov, A., Sarvazyan, N., Wood, R., Magidenko, L., Amin, S., Khosla, S., Ruh, R. J., Ruh, J. M. & Sarvazyan, A., Jul 2014, In : Ultrasonics. 54, 5, p. 1170-1177 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Osteoporosis in men - Consensus is premature

Seeman, E., Bianchi, G., Adami, S., Kanis, J., Khosla, S. & Orwoll, E., Aug 1 2004, In : Calcified Tissue International. 75, 2, p. 120-122 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

Osteoporosis treatment: Recent developments and ongoing challenges

Khosla, S. & Hofbauer, L. C., 2017, (Accepted/In press) In : The Lancet Diabetes and Endocrinology.

Research output: Contribution to journalArticle

122 Scopus citations

Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice

Farr, J., Weivoda, M., Nicks, K. M., Fraser, D. G., Negley, B. A., Onken, J. L., Thicke, B. S., Ruan, M., Liu, H., Forrest, D., Hawse, J. R., Khosla, S. & Monroe, D. G., Apr 1 2018, In : Journal of Bone and Mineral Research. 33, 4, p. 720-731 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

Hofbauer, L. C., Dunstan, C. R., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Sep 29 1998, In : Biochemical and Biophysical Research Communications. 250, 3, p. 776-781 6 p.

Research output: Contribution to journalArticle

260 Scopus citations

Parathyroid Hormone-Related Peptide in Lactation and in Umbilical Cord Blood

KHOSLA, SUNDEEP., JOHANSEN, KEITH. L., ORY, STEVEN. J., O'BRIEN, PETER. C. & KAO, PAI. C., Jan 1 1990, In : Mayo Clinic proceedings. 65, 11, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Pathogenesis of age-related bone loss in humans

Khosla, S., Oct 1 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 10, p. 1226-1235 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Patients with an HbA1c in the prediabetic and diabetic range have higher numbers of circulating cells with osteogenic and endothelial progenitor cell markers

Flammer, A. J., Gössl, M., Li, J., Matsuo, Y., Reriani, M., Loeffler, D., Simari, R. D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4761-4768 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β

Rickard, D. J., Monroe, D. G., Ruesink, T. J., Khosla, S., Riggs, B. L. & Spelsberg, T. C., Jun 1 2003, In : Journal of cellular biochemistry. 89, 3, p. 633-646 14 p.

Research output: Contribution to journalArticle

96 Scopus citations

Polyphenol-rich cranberry juice has a neutral effect on endothelial function but decreases the fraction of osteocalcin-expressing endothelial progenitor cells

Flammer, A. J., Martin, E. A., Gössl, M., Widmer, R. J., Lennon, R. J., Sexton, J. A., Loeffler, D., Khosla, S., Lerman, L. O. & Lerman, A., Feb 1 2013, In : European Journal of Nutrition. 52, 1, p. 289-296 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures

Riggs, B. L., Melton, L. J., Robb, R. A., Camp, J. J., Atkinson, E. J., Oberg, A. L., Rouleau, P. A., McCollough, C. H., Khosla, S. & Bouxsein, M. L., Feb 1 2006, In : Journal of Bone and Mineral Research. 21, 2, p. 315-323 9 p.

Research output: Contribution to journalArticle

82 Scopus citations