• 39889 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

Article

Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women

Syed, F. A., Oursler, M. J., Hefferanm, T. E., Peterson, J. M., Riggs, B. L. & Khosla, S., Sep 2008, In : Osteoporosis International. 19, 9, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

117 Scopus citations
24 Scopus citations

Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line

Hofbauer, L. C., Hicok, K. C. & Khosla, S., Oct 1 1998, In : Journal of Cellular Biochemistry. 71, 1, p. 96-108 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Effects of immunosuppressants on receptor activator of NF-κB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells

Hofbauer, L. C., Shui, C., Riggs, B. L., Dunstan, C. R., Spelsberg, T. C., O'Brien, T. & Khosla, S., 2001, In : Biochemical and Biophysical Research Communications. 280, 1, p. 334-339 6 p.

Research output: Contribution to journalArticle

179 Scopus citations

Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women

Drake, M. M., Srinivasan, B., Mödder, U. I., Ng, A. C., Undale, A. H., Roforth, M. M., Peterson, J. M., McCready, L. K., Riggs, B. L. & Khosla, S., Sep 2011, In : Bone. 49, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Effects of loss of classical estrogen response element signaling on bone in male mice

Syed, F. A., Fraser, D. G., Spelsberg, T. C., Rosen, C. J., Krust, A., Chambon, P., Jameson, J. L. & Khosla, S., Apr 2007, In : Endocrinology. 148, 4, p. 1902-1910 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effects of Loss of Steroid Receptor Coactivator-1 on the Skeletal Response to Estrogen in Mice

Mödder, U. I. L., Sanyal, A., Kearns, A. E., Sibonga, J. D., Nishihara, E., Xu, J., O'Malley, B. W., Ritman, E. L., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Feb 2004, In : Endocrinology. 145, 2, p. 913-921 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

Drake, M. M., Srinivasan, B., Mödder, U. I., Peterson, J. M., McCready, L. K., Riggs, B. L., Dwyer, D., Stolina, M., Kostenuik, P. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5056-5062 7 p.

Research output: Contribution to journalArticle

193 Scopus citations

Effects of physiological variations in circulating insulin levels on bone turnover in humans

Basu, R., Peterson, J., Rizza, R. & Khosla, S., May 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 5, p. 1450-1455 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men

Doran, P. M., Riggs, B. L., Atkinson, E. J. & Khosla, S., 2001, In : Journal of Bone and Mineral Research. 16, 11, p. 2118-2125 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

Effects of sex and age on bone microstructure at the ultradistal radius: A population-based noninvasive in vivo assessment

Khosla, S., Riggs, B. L., Atkinson, E. J., Oberg, A. L., McDaniel, L. J., Holets, M., Peterson, J. M. & Melton, L. J., Jan 2006, In : Journal of Bone and Mineral Research. 21, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

386 Scopus citations

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. M., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., May 2011, In : Obstetrical and Gynecological Survey. 66, 5, p. 289-290 2 p.

Research output: Contribution to journalArticle

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. M., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5063-5068 6 p.

Research output: Contribution to journalArticle

63 Scopus citations

Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men

Sokolnicki, L. A., Khosla, S. & Charkoudian, N., Nov 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 293, 5

Research output: Contribution to journalArticle

10 Scopus citations

Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women

Heshmati, H. M., Riggs, B. L., Burritt, M. F., Mcalister, C. A., Wollan, P. C. & Khosla, S., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 3, p. 751-756 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Emerging role of circulating calcifying cells in the bone-vascular axis

Fadini, G. P., Rattazzi, M., Matsumoto, T., Asahara, T. & Khosla, S., Jun 5 2012, In : Circulation. 125, 22, p. 2772-2781 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Emerging therapeutic opportunities for skeletal restoration

Kawai, M., Mödder, U. I., Khosla, S. & Rosen, C. J., Feb 2011, In : Nature Reviews Drug Discovery. 10, 2, p. 141-156 16 p.

Research output: Contribution to journalArticle

87 Scopus citations

Epidemiology and clinical features of osteoporosis in young individuals

Khosla, S., Lufkin, E. G., Hodgson, S. F., Fitzpatrick, L. A. & Melton, L. J., 1994, In : Bone. 15, 5, p. 551-555 5 p.

Research output: Contribution to journalArticle

132 Scopus citations

Epidemiology of sarcopenia

Melton, J. L., Khosla, S. & Lawrence Riggs, B., 2000, In : Mayo Clinic Proceedings. 75, SUPPL.

Research output: Contribution to journalArticle

66 Scopus citations

Epidemiology of sarcopenia

Melton, L. J., Khosla, S., Crowson, C., O'Connor, M. K., O'Fallon, W. M. & Riggs, B. L., Jun 2000, In : Journal of the American Geriatrics Society. 48, 6, p. 625-630 6 p.

Research output: Contribution to journalArticle

361 Scopus citations

Erratum: Role of circulating osteogenic progenitor cells in calcific aortic stenosis (Journal of the American College of Cardiology (2012) 60 (194553))

Gössl, M., Khosla, S., Zhang, X., Higano, N., Jordan, K. L., Loeffler, D., Sarano, M. E., Lennon, R. J., McGregor, U., Lerman, L. O. & Lerman, A., Dec 18 2012, In : Journal of the American College of Cardiology. 60, 24, p. 2606 1 p.

Research output: Contribution to journalArticle

Erratum: Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women (Diabetes (2007) 56, (753-766))

Basu, R., Man, C. D., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., May 2007, In : Diabetes. 56, 5, p. 1486 1 p.

Research output: Contribution to journalArticle

1 Scopus citations
10 Scopus citations

Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo

Clowes, J. A., Eghbali-Fatourechi, G. Z., McCready, L., Oursler, M. J., Khosla, S. & Riggs, B. L., May 2009, In : Osteoporosis International. 20, 5, p. 761-769 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Estrogen and bone: Insights from estrogen-resistant, aromatase-deficient, and normal men

Khosla, S., Sep 2008, In : Bone. 43, 3, p. 414-417 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Estrogen and fracture risk in men

Gennari, L., Khosla, S. & Bilezikian, J. P., Oct 2008, In : Journal of Bone and Mineral Research. 23, 10, p. 1548-1551 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Estrogen and the skeleton

Khosla, S., Oursler, M. J. & Monroe, D. G., Nov 2012, In : Trends in Endocrinology and Metabolism. 23, 11, p. 576-581 6 p.

Research output: Contribution to journalArticle

234 Scopus citations

Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover

Abdallah, B. M., Bay-Jensen, A. C., Srinivasan, B., Tabassi, N. C., Garnero, P., Delaissé, J. M., Khosla, S. & Kassem, M., Oct 2011, In : Journal of Bone and Mineral Research. 26, 10, p. 2548-2551 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Estrogen receptor beta: the antimechanostat?

Khosla, S., Modder, U. I., Moedder, U. I. & Syed, F. A., Feb 1 2006, In : Bone. 38, 2

Research output: Contribution to journalArticle

1 Scopus citations

Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts

Rickard, D. J., Waters, K. M., Ruesink, T. J., Khosla, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Riggs, B. L. & Spelsberg, T. C., 2002, In : Journal of Bone and Mineral Research. 17, 4, p. 580-592 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβ

Monroe, D. G., Getz, B. J., Johnsen, S., Riggs, B. L., Khosla, S. & Spelsberg, T. C., Oct 1 2003, In : Journal of Cellular Biochemistry. 90, 2, p. 315-326 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: Roles of AF1 and enhancer elements

Monroe, D. G., Secreto, F. J., Hawse, J. R., Subramaniam, M., Khosla, S. & Spelsberg, T. C., Sep 29 2006, In : Journal of Biological Chemistry. 281, 39, p. 28596-28604 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Estrogen receptor α and β heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2Os osteosarcoma cells

Monroe, D. G., Secreto, F. J., Subramaniam, M., Getz, B. J., Khosla, S. & Spelsberg, T. C., Jun 2005, In : Molecular Endocrinology. 19, 6, p. 1555-1568 14 p.

Research output: Contribution to journalArticle

109 Scopus citations
37 Scopus citations

Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform

Waters, K. M., Rickard, D. J., Lawrence Riggs, B., Khosla, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Moore, J. & Spelsberg, T. C., 2001, In : Journal of Cellular Biochemistry. 83, 3, p. 448-462 15 p.

Research output: Contribution to journalArticle

71 Scopus citations

Estrogens and bone health in men

Khosla, S., Melton, L. J. & Riggs, B. L., 2001, In : Calcified Tissue International. 69, 4, p. 189-192 4 p.

Research output: Contribution to journalArticle

61 Scopus citations

Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells

Hofbauer, L. C., Khosla, S., Dunstan, C. R., Lacey, D. L., Spelsberg, T. C. & Riggs, B. L., 1999, In : Endocrinology. 140, 9, p. 4367-4370 4 p.

Research output: Contribution to journalArticle

535 Scopus citations

Estrogen therapy and coronary-artery calcification [3]

Hofbauer, L. C., Khosla, S. & Schoppet, M., Sep 20 2007, In : New England Journal of Medicine. 357, 12, p. 1253-1254 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Etidronate for osteoporosis in primary biliary cirrhosis: A randomized trial

Lindor, K. D., Jorgensen, R. A., Tiegs, R. D., Khosla, S. & Dickson, E. R., 2000, In : Journal of Hepatology. 33, 6, p. 878-882 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Evaluation of a prediction model for long-term fracture risk

Melton, L. J., Atkinson, E. J., Khosla, S., Oberg, A. L. & Lawrence Riggs, B., Apr 2005, In : Journal of Bone and Mineral Research. 20, 4, p. 551-556 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

Sfeir, J. G., Drake, M. M., Atkinson, E. J., Achenbach, S. J., Camp, J. J., Tweed, A. J., McCready, L. K., Yu, L., Adkins, M. C., Amin, S. & Khosla, S., Jul 1 2018, In : Bone. 112, p. 145-152 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency

Riggs, B. L., Khosla, S., Atkinson, E. J., Dunstan, C. R. & Melton, L. J., Sep 2003, In : Osteoporosis International. 14, 9, p. 728-733 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling

Chokalingam, K., Roforth, M. M., Nicks, K. M., McGregor, U., Fraser, D., Khosla, S. & Monroe, D. G., Nov 1 2012, In : Endocrinology. 153, 11, p. 5325-5333 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Examination of nuclear receptor expression in osteoblasts reveals rorβ as an important regulator of osteogenesis

Roforth, M. M., Liu, G., Khosla, S. & Monroe, D. G., Apr 2012, In : Journal of Bone and Mineral Research. 27, 4, p. 891-901 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms

Farley, D. R., Eberhardt, N. L., Grant, C. S., Schaid, D. J., Van Heerden, J. A., Hay, I. D., Khosla, S. & Backdahl, M., 1993, In : World Journal of Surgery. 17, 5, p. 615-621 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Factors associated with proximal femur fracture determined in a large cadaveric cohort

Dragomir Daescu, M. D., Rossman, T. L., Rezaei, A., Carlson, K. D., Kallmes, D. F., Skinner, J. A., Khosla, S. & Amin, S., Nov 1 2018, In : Bone. 116, p. 196-202 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Familial medullary thyroid cancer and prominent corneal nerves: Clinical and genetic analysis

Kane, L. A., Tsai, M. S., Gharib, H., Khosla, S., Robertson, D. M., Schaid, D. J., Honchel, R. & Thibodeau, S. N., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Fat tissue, aging, and cellular senescence

Tchkonia, T., Morbeck, D. E., Von Zglinicki, T., Van Deursen, J., Lustgarten, J., Scrable, H., Khosla, S., Jensen, M. D. & Kirkland, J. L., Oct 2010, In : Aging Cell. 9, 5, p. 667-684 18 p.

Research output: Contribution to journalArticle

426 Scopus citations

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Female reproductive system and bone

Clarke, B. & Khosla, S., Nov 2010, In : Archives of Biochemistry and Biophysics. 503, 1, p. 118-128 11 p.

Research output: Contribution to journalArticle

94 Scopus citations