• 39787 Citations
  • 101 Scopus h-Index
1976 …2021

Research output per year

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Research Output

Article
6 Scopus citations

Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response

Wierman, M., Basson, R., Davis, S., Khosla, S., Miller, K., Rosner, W. & Santoro, N., Nov 2007, In : Journal of Sexual Medicine. 4, 6, p. 1782-1783 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aromatase inhibitor-associated bone fractures: A case-cohort GWAS and functional genomics

Liu, M., Goss, P. E., Ingle, J. N., Kubo, M., Furukawa, Y., Batzler, A., Jenkins, G. D., Carlson, E. E., Nakamura, Y., Schaid, D. J., Chapman, J. A. W., Shepherd, L. E., Ellis, M. J., Khosla, S., Wang, L. M. & Weinshilboum, R. M., Oct 1 2014, In : Molecular Endocrinology. 28, 10, p. 1740-1751 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Assessing forearm fracture risk in postmenopausal women

Melton, L. J., Christen, D., Riggs, B. L., Achenbach, S. J., Müller, R., Van Lenthe, G. H., Amin, S., Atkinson, E. J. & Khosla, S., Jul 2010, In : Osteoporosis International. 21, 7, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

85 Scopus citations

Assessing fracture risk using gradient boosting machine (GBM) models

Atkinson, E. J., Therneau, T. M., Melton, L. J., Camp, J. J., Achenbach, S. J., Amin, S. & Khosla, S., Jun 2012, In : Journal of Bone and Mineral Research. 27, 6, p. 1397-1404 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Assessing the true impact of recurrent fractures on fracture risk

Clarke, B. & Khosla, S., 2009, In : Journal of Bone and Mineral Research. 24, 9, p. 1512-1514 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology

Locklin, R. M., Riggs, B. L., Hicok, K. C., Horton, H. F., Byrne, M. C. & Khosla, S., 2001, In : Journal of Bone and Mineral Research. 16, 12, p. 2192-2204 13 p.

Research output: Contribution to journalArticle

71 Scopus citations

Association of hip strength estimates by finite-element analysis with fractures in women and men

Amin, S., Kopperdhal, D. L., Melton, L. J., Achenbach, S. J., Therneau, T. M., Riggs, B. L., Keaveny, T. M. & Khosla, S., Jul 2011, In : Journal of Bone and Mineral Research. 26, 7, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

70 Scopus citations
843 Scopus citations

Autoimmune hemolytic anemia with both cold and warm autoantibodies.

Nusbaum, N. J. & Khosla, S., Sep 6 1985, In : Journal of the American Medical Association. 254, 9, p. 1175-1176 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Benefits and risks of bisphosphonate therapy for osteoporosis: Editorial comment

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jan 2013, In : Obstetrical and Gynecological Survey. 68, 1, p. 37-39 3 p.

Research output: Contribution to journalArticle

Benefits and risks of bisphosphonate therapy for osteoporosis

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jul 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 7, p. 2272-2282 11 p.

Research output: Contribution to journalArticle

150 Scopus citations

Beta-lactamase inactivation by mechanism-based reagents.

Fisher, J., Belasco, J. G., Charnas, R. L., Khosla, S. & Knowles, J. R., May 16 1980, In : Philosophical transactions of the Royal Society of London. Series B: Biological sciences. 289, 1036, p. 309-319 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Better tools for assessing osteoporosis

Riggs, B. L., Khosla, S. & Melton, L. J., Dec 3 2012, In : Journal of Clinical Investigation. 122, 12, p. 4323-4324 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Lentle, B., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S. & 10 others, Lam, D. K., Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., Ste-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Mar 2009, In : Journal of Rheumatology. 36, 3, p. 478-490 13 p.

Research output: Contribution to journalArticle

122 Scopus citations

Bisphosphonate-associated osteonecrosis of the jaw: Report of a Task Force of the American Society for Bone and Mineral Research

Khosla, S., Burr, D., Cauley, J., Dempster, D. W., Ebeling, P. R., Felsenberg, D., Gagel, R. F., Gilsanz, V., Guise, T., Koka, S., McCauley, L. K., McGowan, J., McKee, M. D., Mohla, S., Pendrys, D. G., Raisz, L. G., Ruggiero, S. L., Shafer, D. M., Shum, L., Silverman, S. L. & 4 others, Van Poznak, C. H., Watts, N., Woo, S. B. & Shane, E., Oct 2007, In : Journal of Bone and Mineral Research. 22, 10, p. 1479-1491 13 p.

Research output: Contribution to journalArticle

1174 Scopus citations

Bisphosphonates: Mechanism of action and role in clinical practice

Drake, M. M., Clarke, B. & Khosla, S., 2008, In : Mayo Clinic Proceedings. 83, 9, p. 1032-1045 14 p.

Research output: Contribution to journalArticle

618 Scopus citations

Bisphosphonates and the upper gastrointestinal tract: Skeletal gain without visceral pain?

Tremaine, W. J. & Khosla, S., Oct 1 2002, In : Mayo Clinic Proceedings. 77, 10, p. 1029-1030 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Body composition during childhood and adolescence: Relations to bone strength and microstructure

Farr, J., Amin, S., LeBrasseur, N. K., Atkinson, E. J., Achenbach, S. J., McCready, L. K., Melton, L. J. & Khosla, S., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, p. 4641-4648 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: A nested substudy of the MAP.3 randomised controlled trial

Cheung, A. M., Tile, L., Cardew, S., Pruthi, S., Robbins, J., Tomlinson, G., Kapral, M. K., Khosla, S., Majumdar, S., Erlandson, M., Scher, J., Hu, H., Demaras, A., Lickley, L., Bordeleau, L., Elser, C., Ingle, J., Richardson, H. & Goss, P. E., Mar 2012, In : The Lancet Oncology. 13, 3, p. 275-284 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Bone fragility in men - Where are we?

Seeman, E., Bianchi, G., Khosla, S., Kanis, J. A. & Orwoll, E., Nov 2006, In : Osteoporosis International. 17, 11, p. 1577-1583 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Bone growth and turnover in progesterone receptor knockout mice

Rickard, D. J., Iwaniec, U. T., Evans, G., Hefferan, T. E., Hunter, J. C., Waters, K. M., Lydon, J. P., O'Malley, B. W., Khosla, S., Spelsberg, T. C. & Turner, R. T., May 2008, In : Endocrinology. 149, 5, p. 2383-2390 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Bone marrow stromal cells express two distinct splice variants of ER-α that are regulated by estrogen

Sanyal, A., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Jan 1 2005, In : Journal of Cellular Biochemistry. 94, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes

Klingberg, E., Lorentzon, M., Göthlin, J., Mellström, D., Geijer, M., Ohlsson, C., Atkinson, E. J., Khosla, S., Carlsten, H. & Forsblad-d'Elia, H., Nov 5 2013, In : Arthritis Research and Therapy. 15, 6, R179.

Research output: Contribution to journalArticle

46 Scopus citations

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS

Ng, A. C., Khosla, S., Charatcharoenwitthaya, N., Kumar, S. K., Achenbach, S. J., Holets, M. F., McCready, L. K., Melton, L. J., Kyle, R. A., Rajkumar, S. V. & Drake, M. M., Dec 15 2011, In : Blood. 118, 25, p. 6529-6534 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

Farr, J., Amin, S., Melton, L. J., Kirmani, S., McCready, L. K., Atkinson, E. J., Müller, R. & Khosla, S., Mar 2014, In : Journal of Bone and Mineral Research. 29, 3, p. 590-599 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

177 Scopus citations

Bone-targeted replacement therapy for hypophosphatasia

Drake, M. M. & Khosla, S., Jun 2008, In : Journal of Bone and Mineral Research. 23, 6, p. 775-776 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Bone turnover across the menopause transition: Correlations with inhibins and follicle-stimulating hormone

Perrien, D. S., Achenbach, S. J., Bledsoe, S. E., Walser, B., Suva, L. J., Khosla, S. & Gaddy, D., May 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Building bone to reverse osteoporosis and repair fractures

Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

273 Scopus citations

Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Firek, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

150 Scopus citations

Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation?

Binkley, N., Lappe, J., Singh, R. J., Khosla, S., Krueger, D., Drezner, M. K. & Blank, R. D., May 1 2015, In : Osteoporosis International. 26, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cellular senescence in bone

Farr, J. & Khosla, S., Apr 1 2019, In : Bone. 121, p. 121-133 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

Shui, C., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Feb 1 2003, In : Journal of Bone and Mineral Research. 18, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

175 Scopus citations

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection

Mödder, U. I., Roforth, M. M., Nicks, K. M., Peterson, J. M., McCready, L. K., Monroe, D. G. & Khosla, S., Mar 2012, In : Bone. 50, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Circulating cells with osteogenic potential

Khosla, S. & Eghbali-Fatourechi, G. Z., Apr 2006, In : Annals of the New York Academy of Sciences. 1068, 1, p. 489-497 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., Sep 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women

McKane, W. R., Khosla, S., Peterson, J. M., Egan, K. & Riggs, B. L., Aug 1994, In : Journal of Bone and Mineral Research. 9, 8, p. 1313-1318 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Circulating osteoblast-lineage cells [4] (multiple letters)

Sata, M., Tanaka, K., Nagai, R., Eghbali-Fatourechi, G. Z. & Khosla, S., Aug 18 2005, In : New England Journal of Medicine. 353, 7, p. 737-738 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Circulating osteoblast-lineage cells in humans

Eghbali-Fatourechi, G. Z., Lamsam, J., Fraser, D., Nagel, D., Riggs, B. L. & Khosla, S., May 12 2005, In : New England Journal of Medicine. 352, 19, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

289 Scopus citations

Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Moedder, U. I. & Khosla, S., Jul 2010, In : Bone. 47, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease

Yang, S. W., Hennessy, R. R., Khosla, S., Lennon, R., Loeffler, D., Sun, T., Liu, Z., Park, K. H., Wang, F. L., Lerman, L. O. & Lerman, A., Jan 15 2017, In : International Journal of Cardiology. 227, p. 833-839 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

Al-Hijji, M., Narula, N., Go, J. L., Khosla, S., Sarano, M. E., Loeffler, D., Lennon, R., Lerman, L. O. & Lerman, A., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium

Barron, M. L., Rybchyn, M. S., Ramesh, S., Mason, R. S., Fiona Bonar, S., Stalley, P., Khosla, S., Hudson, B., Arthur, C., Kim, E., Clifton-Bligh, R. J. & Clifton-Bligh, P. B., Mar 14 2017, In : Bone Research. 5, 16057.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical performance of parathyroid hormone immunometric assays

Kao, P. C., Van Heerden, J. A., Grant, C. S., Klee, G. G. & Khosla, S., 1992, In : Mayo Clinic Proceedings. 67, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Clinical practice guideline: Androgen therapy in women: An Endocrine Society clinical practice guideline

Wierman, M. E., Basson, R., Davis, S. R., Khosla, S., Miller, K. K., Rosner, W. & Santoro, N., Oct 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 10, p. 3697-3710 14 p.

Research output: Contribution to journalArticle

241 Scopus citations

Clinical review 144: Estrogen and the male skeleton

Khosla, S., Joseph Melton, L. & Lawrence Riggs, B., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 4, p. 1443-1450 8 p.

Research output: Contribution to journalArticle

247 Scopus citations