• 40477 Citations
  • 102 Scopus h-Index
1976 …2021

Research output per year

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Research Output

Article

Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women

Syed, F. A., Oursler, M. J., Hefferanm, T. E., Peterson, J. M., Riggs, B. L. & Khosla, S., Sep 1 2008, In : Osteoporosis International. 19, 9, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

120 Scopus citations
25 Scopus citations

Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line

Hofbauer, L. C., Hicok, K. C. & Khosla, S., Oct 1 1998, In : Journal of cellular biochemistry. 71, 1, p. 96-108 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Effects of immunosuppressants on receptor activator of NF-κB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells

Hofbauer, L. C., Shui, C., Riggs, B. L., Dunstan, C. R., Spelsberg, T. C., O'Brien, T. & Khosla, S., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 280, 1, p. 334-339 6 p.

Research output: Contribution to journalArticle

183 Scopus citations

Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women

Drake, M. T., Srinivasan, B., Mödder, U. I., Ng, A. C., Undale, A. H., Roforth, M. M., Peterson, J. M., McCready, L. K., Riggs, B. L. & Khosla, S., Sep 1 2011, In : Bone. 49, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of loss of classical estrogen response element signaling on bone in male mice

Syed, F. A., Fraser, D. G., Spelsberg, T. C., Rosen, C. J., Krust, A., Chambon, P., Jameson, J. L. & Khosla, S., Apr 1 2007, In : Endocrinology. 148, 4, p. 1902-1910 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effects of Loss of Steroid Receptor Coactivator-1 on the Skeletal Response to Estrogen in Mice

Mödder, U. I. L., Sanyal, A., Kearns, A. E., Sibonga, J. D., Nishihara, E., Xu, J., O'Malley, B. W., Ritman, E. L., Riggs, B. L., Spelsberg, T. C. & Khosla, S., Feb 1 2004, In : Endocrinology. 145, 2, p. 913-921 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

Drake, M. T., Srinivasan, B., Mödder, U. I., Peterson, J. M., McCready, L. K., Riggs, B. L., Dwyer, D., Stolina, M., Kostenuik, P. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5056-5062 7 p.

Research output: Contribution to journalArticle

194 Scopus citations

Effects of physiological variations in circulating insulin levels on bone turnover in humans

Basu, R., Peterson, J., Rizza, R. & Khosla, S., May 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 5, p. 1450-1455 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men

Doran, P. M., Riggs, B. L., Atkinson, E. J. & Khosla, S., Jan 1 2001, In : Journal of Bone and Mineral Research. 16, 11, p. 2118-2125 8 p.

Research output: Contribution to journalArticle

94 Scopus citations

Effects of sex and age on bone microstructure at the ultradistal radius: A population-based noninvasive in vivo assessment

Khosla, S., Riggs, B. L., Atkinson, E. J., Oberg, A. L., McDaniel, L. J., Holets, M., Peterson, J. M. & Melton, L. J., Jan 1 2006, In : Journal of Bone and Mineral Research. 21, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

390 Scopus citations

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women

Drake, M. T., McCready, L. K., Hoey, K. A., Atkinson, E. J. & Khosla, S., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 5063-5068 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men

Sokolnicki, L. A., Khosla, S. & Charkoudian, N., Nov 1 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 293, 5, p. E1426-E1429

Research output: Contribution to journalArticle

10 Scopus citations

Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women

Heshmati, H. M., Riggs, B. L., Burritt, M. F., Mcalister, C. A., Wollan, P. C. & Khosla, S., Nov 11 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 3, p. 751-756 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Emerging role of circulating calcifying cells in the bone-vascular axis

Fadini, G. P., Rattazzi, M., Matsumoto, T., Asahara, T. & Khosla, S., Jun 5 2012, In : Circulation. 125, 22, p. 2772-2781 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Epidemiology and clinical features of osteoporosis in young individuals

Khosla, S., Lufkin, E. G., Hodgson, S. F., Fitzpatrick, L. A. & Melton, L. J., Jan 1 1994, In : Bone. 15, 5, p. 551-555 5 p.

Research output: Contribution to journalArticle

133 Scopus citations

Epidemiology of sarcopenia

Melton, L. J., Khosla, S., Crowson, C. S., O'Connor, M. K., O'Fallon, W. M. & Riggs, B. L., Jun 1 2000, In : Journal of the American Geriatrics Society. 48, 6, p. 625-630 6 p.

Research output: Contribution to journalArticle

363 Scopus citations

Epidemiology of sarcopenia

Melton, J. L., Khosla, S. & Lawrence Riggs, B., Jan 1 2000, In : Mayo Clinic proceedings. 75, SUPPL., p. S10-S13

Research output: Contribution to journalArticle

67 Scopus citations

Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo

Clowes, J. A., Eghbali-Fatourechi, G. Z., McCready, L., Oursler, M. J., Khosla, S. & Riggs, B. L., May 1 2009, In : Osteoporosis International. 20, 5, p. 761-769 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover

Abdallah, B. M., Bay-Jensen, A. C., Srinivasan, B., Tabassi, N. C., Garnero, P., Delaissé, J. M., Khosla, S. & Kassem, M., Oct 1 2011, In : Journal of Bone and Mineral Research. 26, 10, p. 2548-2551 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Estrogen receptor beta: the antimechanostat?

Khosla, S., Modder, U. I., Moedder, U. I. & Syed, F. A., Feb 1 2006, In : Bone. 38, 2

Research output: Contribution to journalArticle

1 Scopus citations

Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts

Rickard, D. J., Waters, K. M., Ruesink, T. J., Khosla, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Riggs, B. L. & Spelsberg, T. C., Jan 1 2002, In : Journal of Bone and Mineral Research. 17, 4, p. 580-592 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβ

Monroe, D. G., Getz, B. J., Johnsen, S. A., Riggs, B. L., Khosla, S. & Spelsberg, T. C., Oct 1 2003, In : Journal of cellular biochemistry. 90, 2, p. 315-326 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: Roles of AF1 and enhancer elements

Monroe, D. G., Secreto, F. J., Hawse, J. R., Subramaniam, M., Khosla, S. & Spelsberg, T. C., Sep 29 2006, In : Journal of Biological Chemistry. 281, 39, p. 28596-28604 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Estrogen receptor α and β heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2Os osteosarcoma cells

Monroe, D. G., Secreto, F. J., Subramaniam, M., Getz, B. J., Khosla, S. & Spelsberg, T. C., Jun 1 2005, In : Molecular Endocrinology. 19, 6, p. 1555-1568 14 p.

Research output: Contribution to journalArticle

110 Scopus citations

Estrogen receptor β isoform-specific induction of transforming growth factor β-inducible early gene-1 in human osteoblast cells: An essential role for the activation function 1 domain

Hawse, J. R., Subramaniam, M., Monroe, D. G., Hemmingsen, A. H., Ingle, J. N., Khosla, S., Oursler, M. J. & Spelsberg, T. C., Jul 1 2008, In : Molecular Endocrinology. 22, 7, p. 1579-1595 17 p.

Research output: Contribution to journalArticle

37 Scopus citations

Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform

Waters, K. M., Rickard, D. J., Lawrence Riggs, B., Khosla, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Moore, J. & Spelsberg, T. C., Nov 13 2001, In : Journal of cellular biochemistry. 83, 3, p. 448-462 15 p.

Research output: Contribution to journalArticle

71 Scopus citations

Estrogens and bone health in men

Khosla, S., Melton, L. J. & Riggs, B. L., Nov 17 2001, In : Calcified Tissue International. 69, 4, p. 189-192 4 p.

Research output: Contribution to journalArticle

61 Scopus citations

Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells

Hofbauer, L. C., Khosla, S., Dunstan, C. R., Lacey, D. L., Spelsberg, T. C. & Riggs, B. L., Jan 1 1999, In : Endocrinology. 140, 9, p. 4367-4370 4 p.

Research output: Contribution to journalArticle

Open Access
539 Scopus citations

Etidronate for osteoporosis in primary biliary cirrhosis: A randomized trial

Lindor, K. D., Jorgensen, R. A., Tiegs, R. D., Khosla, S. & Dickson, E. R., Jan 1 2000, In : Journal of hepatology. 33, 6, p. 878-882 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

Sfeir, J. G., Drake, M. M., Atkinson, E. J., Achenbach, S. J., Camp, J. J., Tweed, A. J., McCready, L. K., Yu, L., Adkins, M. C., Amin, S. & Khosla, S., Jul 1 2018, In : Bone. 112, p. 145-152 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency

Riggs, B. L., Khosla, S., Atkinson, E. J., Dunstan, C. R. & Melton, L. J., Sep 1 2003, In : Osteoporosis International. 14, 9, p. 728-733 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling

Chokalingam, K., Roforth, M. M., Nicks, K. M., McGregor, U., Fraser, D., Khosla, S. & Monroe, D. G., Nov 1 2012, In : Endocrinology. 153, 11, p. 5325-5333 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Examination of nuclear receptor expression in osteoblasts reveals rorβ as an important regulator of osteogenesis

Roforth, M. M., Liu, G., Khosla, S. & Monroe, D. G., Apr 1 2012, In : Journal of Bone and Mineral Research. 27, 4, p. 891-901 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms

Farley, D. R., Eberhardt, N. L., Grant, C. S., Schaid, D. J., van Heerden, J. A., Hay, I. D. & Khosla, S., Sep 1 1993, In : World Journal of Surgery. 17, 5, p. 615-620 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Factors associated with proximal femur fracture determined in a large cadaveric cohort

Dragomir Daescu, M. D., Rossman, T. L., Rezaei, A., Carlson, K. D., Kallmes, D. F., Skinner, J. A., Khosla, S. & Amin, S., Nov 1 2018, In : Bone. 116, p. 196-202 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Familial medullary thyroid cancer and prominent corneal nerves: Clinical and genetic analysis

Kane, L. A., Tsai, M. S., Gharib, H., Khosla, S., Robertson, D. M., Schaid, D. J., Honchel, R. & Thibodeau, S. N., Jan 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 1, p. 289-293 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
72 Scopus citations

Fracture Incidence and Characteristics in Young Adults Aged 18 to 49 Years: A Population-Based Study

Farr, J., Melton, L. J., Achenbach, S. J., Atkinson, E. J., Khosla, S. & Amin, S., Dec 1 2017, In : Journal of Bone and Mineral Research. 32, 12, p. 2347-2354 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Fracture Risk After Bilateral Oophorectomy in Elderly Women

Melton, L. J., Khosla, S., Malkasian, G. D., Achenbach, S. J., Oberg, A. L. & Riggs, B. L., May 1 2003, In : Journal of Bone and Mineral Research. 18, 5, p. 900-905 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Fracture risk after surgery for peptic ulcer disease: A population-based cohort study

Melton, L. J., Crowson, C. S., Khosla, S. & O'Fallon, W. M., Jul 1 1999, In : Bone. 25, 1, p. 61-67 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Fracture risk among patients with urolithiasis: A population-based cohort study

Melton, L. J., Crowson, C. S., Khosla, S., Wilson, D. M. & O'Fallon, W. M., Jan 1 1998, In : Kidney international. 53, 2, p. 459-464 6 p.

Research output: Contribution to journalArticle

114 Scopus citations

Fracture risk following bilateral orchiectomy

Melton, L. J., Alothman, K. I., Khosla, S., Achenbach, S. J., Oberg, A. L. & Zincke, H., May 1 2003, In : Journal of Urology. 169, 5, p. 1747-1750 4 p.

Research output: Contribution to journalArticle

130 Scopus citations

Fracture risk in men with prostate cancer: A population-based study

Melton, L. J., Lieber, M. M., Atkinson, E. J., Achenbach, S. J., Zincke, H., Therneau, T. M. & Khosla, S., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1808-1815 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Fracture risk in monoclonal gammopathy of undetermined significance

Melton, L. J., Rajkumar, S. V., Khosla, S., Achenbach, S. J., Oberg, A. L. & Kyle, R. A., Jan 1 2004, In : Journal of Bone and Mineral Research. 19, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

118 Scopus citations

Fracture risk in primary hyperparathyroidism

Khosla, S. & Melton, L. J., Nov 1 2002, In : Journal of Bone and Mineral Research. 17, SUPPL. 2, p. N103-N107

Research output: Contribution to journalArticle

69 Scopus citations

Fracture risk in type 2 diabetes: Update of a population-based study

Melton, L. J., Leibson, C. L., Achenbach, S. J., Therneau, T. M. & Khosla, S., Aug 1 2008, In : Journal of Bone and Mineral Research. 23, 8, p. 1334-1342 9 p.

Research output: Contribution to journalArticle

230 Scopus citations

Fracture risk in women with breast cancer: A population-based study

Melton, L. J., Hartmann, L. C., Achenbach, S. J., Atkinson, E. J., Therneau, T. M. & Khosla, S., May 1 2012, In : Journal of Bone and Mineral Research. 27, 5, p. 1196-1205 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Fractures following thyroidectomy in women: A population-based cohort study

Melton, L. J., Ardila, E., Crowson, C. S., O'Fallon, W. M. & Khosla, S., Nov 13 2000, In : Bone. 27, 5, p. 695-700 6 p.

Research output: Contribution to journalArticle

15 Scopus citations