• 39555 Citations
  • 101 Scopus h-Index
1976 …2021
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Research Output 1980 2020

Article
45 Citations (Scopus)

Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

Farr, J., Amin, S., Melton, L. J., Kirmani, S., McCready, L. K., Atkinson, E. J., Müller, R. & Khosla, S., Mar 2014, In : Journal of Bone and Mineral Research. 29, 3, p. 590-599 10 p.

Research output: Contribution to journalArticle

Forearm
Bone and Bones
Wounds and Injuries
Tibia
Growth
177 Citations (Scopus)

Bone structure at the distal radius during adolescent growth

Kirmani, S., Christen, D., Van Lenthe, G. H., Fischer, P. R., Bouxsein, M. L., McCready, L. K., Melton, L. J., Riggs, B. L., Amin, S., Müller, R. & Khosla, S., Jun 2009, In : Journal of Bone and Mineral Research. 24, 6, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

Puberty
Forearm
Bone and Bones
Growth
Age Groups
5 Citations (Scopus)

Bone-targeted replacement therapy for hypophosphatasia

Drake, M. M. & Khosla, S., Jun 2008, In : Journal of Bone and Mineral Research. 23, 6, p. 775-776 2 p.

Research output: Contribution to journalArticle

Hypophosphatasia
Biological Therapy
Alkaline Phosphatase
Bone and Bones
Therapeutics
83 Citations (Scopus)

Bone turnover across the menopause transition: Correlations with inhibins and follicle-stimulating hormone

Perrien, D. S., Achenbach, S. J., Bledsoe, S. E., Walser, B., Suva, L. J., Khosla, S. & Gaddy, D., May 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

Inhibins
Bone Remodeling
Follicle Stimulating Hormone
Menopause
Bone
273 Citations (Scopus)

Building bone to reverse osteoporosis and repair fractures

Khosla, S., Westendorf, J. J. & Oursler, M. J., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

Osteoporosis
Fracture Healing
Bone and Bones
Spinal Fractures
Bone Morphogenetic Protein 2
141 Citations (Scopus)

Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism

Khosla, S., Ebeling, P. R., Firek, A. F., Burritt, M. M., Kao, P. C. & Heath, H., Mar 1993, In : Journal of Clinical Endocrinology and Metabolism. 76, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

Parathyroid Glands
Primary Hyperparathyroidism
Calcium
Tumors
Plasmas
150 Citations (Scopus)

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw

Khan, A. A., Sándor, G. K. B., Dore, E., Morrison, A. D., Alsahli, M., Amin, F., Peters, E., Hanley, D. A., Chaudry, S. R., Dempster, D. W., Glorieux, F. H., Neville, A. J., Talwar, R. M., Clokie, C. M., Al Mardini, M., Paul, T., Khosla, S., Josse, R. G., Sutherland, S., Lam, D. K. & 9 others, Carmichael, R. P., Blanas, N., Kendler, D., Petak, S., St.-Marie, L. G., Brown, J., Evans, A. W., Rios, L. & Compston, J. E., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1391-1397 7 p.

Research output: Contribution to journalArticle

Bisphosphonate-Associated Osteonecrosis of the Jaw
Osteonecrosis
Diphosphonates
Jaw
Practice Guidelines
14 Citations (Scopus)

Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation?

Binkley, N., Lappe, J., Singh, R. J., Khosla, S., Krueger, D., Drezner, M. K. & Blank, R. D., May 1 2015, In : Osteoporosis International. 26, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

Vitamin D
Cholecalciferol
Serum
Linear Models
Prospective Studies
9 Citations (Scopus)

Cellular senescence in bone

Farr, J. & Khosla, S., Apr 1 2019, In : Bone. 121, p. 121-133 13 p.

Research output: Contribution to journalArticle

Cell Aging
Bone and Bones
Osteoporosis
Phenotype
Chronic Disease
174 Citations (Scopus)

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

Shui, C., Spelsberg, T. C., Riggs, B. L. & Khosla, S., Feb 1 2003, In : Journal of Bone and Mineral Research. 18, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

Osteoblasts
Mesenchymal Stromal Cells
Messenger RNA
Core Binding Factor Alpha 1 Subunit
Rodentia
107 Citations (Scopus)

Characterization of circulating osteoblast lineage cells in humans

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., May 2007, In : Bone. 40, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

Osteoblasts
Osteocalcin
Population
Alkaline Phosphatase
Bone Remodeling
35 Citations (Scopus)

Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection

Mödder, U. I., Roforth, M. M., Nicks, K. M., Peterson, J. M., McCready, L. K., Monroe, D. G. & Khosla, S., Mar 2012, In : Bone. 50, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone Marrow
Osteoblasts
Population
Osteoporosis
69 Citations (Scopus)

Circulating cells with osteogenic potential

Khosla, S. & Eghbali-Fatourechi, G. Z., Apr 2006, In : Annals of the New York Academy of Sciences. 1068, 1, p. 489-497 9 p.

Research output: Contribution to journalArticle

Bone
Blood
Osteoblasts
Plastics
Flow cytometry

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-1 Receptors
Cytokines
Bone
Interleukin-6
83 Citations (Scopus)

Circulating cytokine levels in osteoporotic and normal women

Khosla, S., Peterson, J. M., Egan, K., Jones, J. D. & Riggs, B. L., Sep 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 3, p. 707-711 5 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-1 Receptors
Cytokines
Bone
Interleukin-6
86 Citations (Scopus)

Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women

McKane, W. R., Khosla, S., Peterson, J. M., Egan, K. & Riggs, B. L., Aug 1994, In : Journal of Bone and Mineral Research. 9, 8, p. 1313-1318 6 p.

Research output: Contribution to journalArticle

Bone Resorption
Menopause
Interleukin-1
Cytokines
Interleukin-1 Receptors
17 Citations (Scopus)

Circulating osteoblast-lineage cells [4] (multiple letters)

Sata, M., Tanaka, K., Nagai, R., Eghbali-Fatourechi, G. Z. & Khosla, S., Aug 18 2005, In : New England Journal of Medicine. 353, 7, p. 737-738 2 p.

Research output: Contribution to journalArticle

Calcinosis
Bone Remodeling
Cell Lineage
Stromal Cells
Osteoblasts
288 Citations (Scopus)

Circulating osteoblast-lineage cells in humans

Eghbali-Fatourechi, G. Z., Lamsam, J., Fraser, D., Nagel, D., Riggs, B. L. & Khosla, S., May 12 2005, In : New England Journal of Medicine. 352, 19, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

Osteoblasts
Osteogenesis
Osteocalcin
Bone and Bones
Growth
27 Citations (Scopus)

Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Moedder, U. I. & Khosla, S., Jul 2010, In : Bone. 47, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Alkaline Phosphatase
Bone Marrow
Bone Marrow Cells
Messenger RNA
10 Citations (Scopus)

Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease

Yang, S. W., Hennessy, R. R., Khosla, S., Lennon, R., Loeffler, D., Sun, T., Liu, Z., Park, K. H., Wang, F. L., Lerman, L. O. & Lerman, A., Jan 15 2017, In : International Journal of Cardiology. 227, p. 833-839 7 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Cell Count
Biomarkers
Coronary Stenosis
Cause of Death
2 Citations (Scopus)

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

Al-Hijji, M., Narula, N., Go, J. L., Khosla, S., Sarano, M. E., Loeffler, D., Lennon, R., Lerman, L. O. & Lerman, A., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Stem Cells
Phenotype
Vascular Endothelial Growth Factor Receptor-2
Aortic Valve
2 Citations (Scopus)

Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium

Barron, M. L., Rybchyn, M. S., Ramesh, S., Mason, R. S., Fiona Bonar, S., Stalley, P., Khosla, S., Hudson, B., Arthur, C., Kim, E., Clifton-Bligh, R. J. & Clifton-Bligh, P. B., Mar 14 2017, In : Bone Research. 5, 16057.

Research output: Contribution to journalArticle

Osteoblasts
Bone and Bones
Up-Regulation
Osteosclerosis
Aquaporin 1
70 Citations (Scopus)

Clinical performance of parathyroid hormone immunometric assays

Kao, P. C., Van Heerden, J. A., Grant, C. S., Klee, G. G. & Khosla, S., 1992, In : Mayo Clinic Proceedings. 67, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Immunoradiometric Assay
Primary Hyperparathyroidism
Hypercalcemia
Radioimmunoassay
241 Citations (Scopus)

Clinical practice guideline: Androgen therapy in women: An Endocrine Society clinical practice guideline

Wierman, M. E., Basson, R., Davis, S. R., Khosla, S., Miller, K. K., Rosner, W. & Santoro, N., Oct 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 10, p. 3697-3710 14 p.

Research output: Contribution to journalArticle

Practice Guidelines
Androgens
Advisory Committees
Testosterone
Guidelines
247 Citations (Scopus)

Clinical review 144: Estrogen and the male skeleton

Khosla, S., Joseph Melton, L. & Lawrence Riggs, B., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 4, p. 1443-1450 8 p.

Research output: Contribution to journalArticle

Skeleton
Bone
Estrogens
Aromatase
Bone Remodeling
38 Citations (Scopus)

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I

Engelke, K., Lang, T., Khosla, S., Qin, L., Zysset, P., Leslie, W. D., Shepherd, J. A. & Schousboe, J. T., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 338-358 21 p.

Research output: Contribution to journalArticle

Densitometry
Osteoporosis
Hip
Tomography
Finite Element Analysis
45 Citations (Scopus)

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III

Engelke, K., Lang, T., Khosla, S., Qin, L., Zysset, P., Leslie, W. D., Shepherd, J. A. & Shousboe, J. T., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 393-407 15 p.

Research output: Contribution to journalArticle

Densitometry
Osteoporosis
Tomography
Hip
Finite Element Analysis
57 Citations (Scopus)

Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II

Zysset, P., Qin, L., Lang, T., Khosla, S., Leslie, W. D., Shepherd, J. A., Schousboe, J. T. & Engelke, K., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 359-392 34 p.

Research output: Contribution to journalArticle

Finite Element Analysis
Densitometry
Osteoporosis
Hip
Spine
56 Citations (Scopus)
Immunoassay
Bone Density
Mass Spectrometry
Steroids
Serum
27 Citations (Scopus)

Comprehensive assessment of osteoporosis and bone fragility with ct colonography

Fidler, J. L., Murthy, N. S., Khosla, S., Clarke, B., Bruining, D. H., Kopperdahl, D. L., Lee, D. C. & Keaveny, T. M., Jan 1 2016, In : Radiology. 278, 1, p. 172-180 9 p.

Research output: Contribution to journalArticle

Osteoporosis
X-Rays
Bone and Bones
Computed Tomographic Colonography
Confidence Intervals
63 Citations (Scopus)

Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair

Khosla, S., Westendorf, J. J. & Mödder, U. I., Dec 2010, In : Stem Cells. 28, 12, p. 2124-2128 5 p.

Research output: Contribution to journalArticle

Bone Remodeling
Cell- and Tissue-Based Therapy
Stem Cells
Fracture Healing
Bone and Bones
147 Citations (Scopus)

Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women

Melton, L. J., Riggs, B. L., Van Lenthe, G. H., Achenbach, S. J., Müller, R., Bouxsein, M. L., Amin, S., Atkinson, E. J. & Khosla, S., Sep 2007, In : Journal of Bone and Mineral Research. 22, 9, p. 1442-1448 7 p.

Research output: Contribution to journalArticle

Forearm
Bone and Bones
Colles' Fracture
Osteoporotic Fractures
ROC Curve
87 Citations (Scopus)
Bone Density
Odds Ratio
Confidence Intervals
Femur Neck
Pelvic Bones
51 Citations (Scopus)

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells

Gössl, M., Mödder, U. I., Gulati, R., Rihal, C., Prasad, A., Loeffler, D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 2010, In : European Heart Journal. 31, 23, p. 2909-2914 6 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Coronary Circulation
Interleukin-8
erucylphosphocholine
Endothelial Progenitor Cells
22 Citations (Scopus)

Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women

Prasad, M., Reriani, M., Khosla, S., Gössl, M., Lennon, R., Gulati, R., Prasad, A., Lerman, L. O. & Lerman, A., 2014, In : Vascular Health and Risk Management. 10, p. 533-538 6 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Osteoporosis
Coronary Artery Disease
Blood Vessels
Coronary Vessels
163 Citations (Scopus)

Correlates of osteoprotegerin levels in women and men

Khosla, S., Arrighi, H. M., Melton, L. J., Atkinson, E. J., O'Fallon, W. M., Dunstan, C. & Riggs, B. L., 2002, In : Osteoporosis International. 13, 5, p. 394-399 6 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Bone Remodeling
Bone Density
Bone and Bones
Serum
1 Citation (Scopus)

Corrigendum to "Characterization of circulating osteoblast lineage cells in humans" [Bone 40 (2007) 1370-1377] (DOI: 10.1016/j.bone.2006.12.064)

Eghbali-Fatourechi, G. Z., Mödder, U. I. L., Charatcharoenwitthaya, N., Sanyal, A., Undale, A. H., Clowes, J. A., Tarara, J. E. & Khosla, S., Oct 2007, In : Bone. 41, 4, p. 741 1 p.

Research output: Contribution to journalArticle

Osteoblasts
Bone and Bones
corrigendum

Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]

Undale, A., Srinivasan, B., Drake, M. M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Modder, U. I. & Khosla, S., Mar 1 2011, In : Bone. 48, 3, p. 671 1 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Bone and Bones
corrigendum

Corrigendum to "Letter to the Editor" [Bone 38 (2006) 289]

Khosla, S., Modder, U. I. & Syed, F. A., Mar 1 2011, In : Bone. 48, 3, p. 670 1 p.

Research output: Contribution to journalArticle

Bone and Bones
corrigendum
23 Citations (Scopus)

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study

Samelson, E. J., Broe, K. E., Xu, H., Yang, L., Boyd, S., Biver, E., Szulc, P., Adachi, J., Amin, S., Atkinson, E., Berger, C., Burt, L., Chapurlat, R., Chevalley, T., Ferrari, S., Goltzman, D., Hanley, D. A., Hannan, M. T., Khosla, S., Liu, C. T. & 13 others, Lorentzon, M., Mellstrom, D., Merle, B., Nethander, M., Rizzoli, R., Sornay-Rendu, E., Van Rietbergen, B., Sundh, D., Wong, A. K. O., Ohlsson, C., Demissie, S., Kiel, D. P. & Bouxsein, M. L., Jan 1 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

Bone Density
Prospective Studies
Bone and Bones
Femur Neck
Tibia
99 Citations (Scopus)

Cortical porosity identifies women with osteopenia at increased risk for forearm fractures

Bala, Y., Zebaze, R., Ghasem-Zadeh, A., Atkinson, E. J., Iuliano, S., Peterson, J. M., Amin, S., Bjørnerem, Å., Melton, L. J., Johansson, H., Kanis, J. A., Khosla, S. & Seeman, E., 2014, In : Journal of Bone and Mineral Research. 29, 6, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

Metabolic Bone Diseases
Porosity
Forearm
Bone Density
Osteoporosis

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Bairn, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Aug 2008, In : Obstetrical and Gynecological Survey. 63, 8, p. 516-517 2 p.

Research output: Contribution to journalArticle

319 Citations (Scopus)

Cost-effective osteoporosis treatment thresholds: The United States perspective

Tosteson, A. N. A., Melton, L. J., Dawson-Hughes, B., Baim, S., Favus, M. J., Khosla, S. & Lindsay, R. L., Apr 2008, In : Osteoporosis International. 19, 4, p. 437-447 11 p.

Research output: Contribution to journalArticle

Hip Fractures
Osteoporosis
Health Care Costs
Costs and Cost Analysis
Quality-Adjusted Life Years
94 Citations (Scopus)

Cross-sectional versus longitudinal evaluation of bone loss in men and women

Melton, L. J., Khosla, S., Atkinson, E. J., O'Connor, M. K., O'Fallon, W. M. & Riggs, B. L., 2000, In : Osteoporosis International. 11, 7, p. 592-599 8 p.

Research output: Contribution to journalArticle

Bone and Bones
Bone Density
Hormone Replacement Therapy
Photon Absorptiometry
Forearm
58 Citations (Scopus)

Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women

Kassem, M., Khosla, S., Spelsberg, T. C. & Riggs, B. L., 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 2, p. 513-518 6 p.

Research output: Contribution to journalArticle

Bone
Estrogens
Bone Marrow
Cytokines
Interleukin-1
38 Citations (Scopus)

Cytokine-specific induction of the TGF-β inducible early gene (TIEG): Regulation by specific members of the TGF-β family

Hefferan, T. E., Subramaniam, M., Khosla, S., Riggs, B. L. & Spelsberg, T. C., 2000, In : Journal of Cellular Biochemistry. 78, 3, p. 380-390 11 p.

Research output: Contribution to journalArticle

Gene expression
Genes
Cytokines
Bone Morphogenetic Protein 6
Activins
16 Citations (Scopus)

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

Nicks, K. M., Fujita, K., Fraser, D., Mcgregor, U., Drake, M. M., Mcgee-Lawrence, M. E., Westendorf, J. J., Monroe, D. G. & Khosla, S., 2015, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Osteoblasts
Bone and Bones
Bone Remodeling
Bone Resorption
66 Citations (Scopus)

Determinants of bone strength and quality in diabetes mellitus in humans

Farr, J. & Khosla, S., Jan 1 2016, In : Bone. 82, p. 28-34 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Diabetes Mellitus
Bone and Bones
Porosity
Bone Remodeling
4 Citations (Scopus)

Determinants of forearm strength in postmenopausal women

Melton, L. J., Riggs, B. L., Müller, R., Achenbach, S. J., Christen, D., Atkinson, E. J., Amin, S. & Khosla, S., Dec 2011, In : Osteoporosis International. 22, 12, p. 3047-3054 8 p.

Research output: Contribution to journalArticle

Forearm
Bone and Bones
Bone Density
Steroids
Tomography
13 Citations (Scopus)

Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene

Hofbauer, L. C., Hicok, K. C., Schroeder, M. J., Harris, S. A., Robinson, J. A. & Khosla, S., Sep 15 1997, In : Journal of Cellular Biochemistry. 66, 4, p. 542-551 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Genes
Cells
Cell Line
Androgens