• 11854 Citations
  • 63 Scopus h-Index
1976 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1981 2019

  • 11854 Citations
  • 63 Scopus h-Index
  • 343 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Chapter
2019
9 Citations (Scopus)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., De Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Mitochondria
Mitochondrial DNA
Genes
Waist-Hip Ratio
1 Citation (Scopus)

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (Nature Communications, (2018), 9, 1, (2098), 10.1038/s41467-018-04362-x)

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, R., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2019, In : Nature communications. 10, 1, 2068.

Research output: Contribution to journalComment/debate

Open Access
document markup languages
HTML
Genetic Loci
loci
lists

Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies

Solayman, M. H., Langaee, T. Y., Gong, Y., Shahin, M. H., Turner, S. T., Chapman, A. B., Gums, J. G., Boerwinkle, E., Beitelshees, A. L., El-Hamamsy, M., El-Wakeel, L., Cooper-DeHoff, R. M., Badary, O. A. & Johnson, J. A., Apr 1 2019, In : European Journal of Pharmaceutical Sciences. 131, p. 93-98 6 p.

Research output: Contribution to journalArticle

Pharmacogenetics
MicroRNAs
Antihypertensive Agents
Metoprolol
Atenolol

Gene variants at loci related to blood pressure account for variation in response to antihypertensive drugs between black and white individuals: Genomic precision medicine may dispense with ethnicity

Iniesta, R., Campbell, D., Venturini, C., Faconti, L., Singh, S., Irvin, M. R., Cooper-Dehoff, R. M., Johnson, J. A., Turner, S. T., Arnett, D. K., Weale, M. E., Warren, H., Munroe, P. B., Cruickshank, K., Padmanabhan, S., Lewis, C. & Chowienczyk, P., Sep 1 2019, In : Hypertension. 74, 3, p. 614-622 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Antihypertensive Agents
Sodium Chloride Symporter Inhibitors
Hydrochlorothiazide
Angiotensin Receptor Antagonists

Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response

Singh, S., McDonough, C. W., Gong, Y., Bailey, K. R., Boerwinkle, E., Chapman, A. B., Gums, J. G., Turner, S. T., Cooper-DeHoff, R. M. & Johnson, J. A., Dec 1 2019, In : Scientific reports. 9, 1, 17323.

Research output: Contribution to journalArticle

Open Access
Thiazides
Sodium Chloride Symporter Inhibitors
Chromosomes, Human, Pair 2
Chlorthalidone
Genome
1 Citation (Scopus)

Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

Singh, S., Warren, H. R., Hiltunen, T. P., McDonough, C. W., El Rouby, N., Salvi, E., Wang, Z., Garofalidou, T., Fyhrquist, F., Kontula, K. K., Glorioso, V., Zaninello, R., Glorioso, N., Pepine, C. J., Munroe, P. B., Turner, S. T., Chapman, A. B., Boerwinkle, E., Johnson, J. A., Gong, Y. & 1 others, Cooper-DeHoff, R. M., Aug 20 2019, In : Journal of the American Heart Association. 8, 16, e013115.

Research output: Contribution to journalReview article

Open Access
Antihypertensive Agents
Meta-Analysis
Genome
Blood Pressure
Single Nucleotide Polymorphism
2 Citations (Scopus)

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans

Singh, S., El Rouby, N., McDonough, C. W., Gong, Y., Bailey, K. R., Boerwinkle, E., Chapman, A. B., Gums, J. G., Turner, S. T., Cooper-DeHoff, R. M. & Johnson, J. A., Sep 1 2019, In : Clinical and translational science. 12, 5, p. 497-504 8 p.

Research output: Contribution to journalArticle

Open Access
Blood pressure
Blood Pressure
Antihypertensive Agents
Atenolol
Dual Specificity Phosphatase 3

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers

Cunningham, P. N., Wang, Z., Grove, M. L., Cooper-DeHoff, R. M., Beitelshees, A. L., Gong, Y., Gums, J. G., Johnson, J. A., Turner, S. T., Boerwinkle, E. & Chapman, A. B., Jan 1 2019, In : PloS one. 14, 9, e0221957.

Research output: Contribution to journalArticle

Open Access
angiotensins
Angiotensin Receptors
Blood pressure
blood pressure
African Americans

Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

Smith, J. A., Raisky, J., Ratliff, S. M., Liu, J., Kardia, S. L. R., Turner, S. T., Mosley, T. H. & Zhao, W., Oct 22 2019, In : BMC medical genomics. 12, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Epigenomics
African Americans
DNA Methylation
Blood Pressure
Kidney
1 Citation (Scopus)

Longitudinal analysis of epigenome-wide DNA methylation reveals novel smoking-related loci in African Americans

Liu, J., Zhao, W., Ammous, F., Turner, S. T., Mosley, T. H., Zhou, X. & Smith, J. A., Jan 1 2019, In : Epigenetics.

Research output: Contribution to journalArticle

DNA Methylation
African Americans
Smoking
Methylation
Epigenomics
7 Citations (Scopus)

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Understanding Society Scientific Group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In : Nature Genetics. 51, 4, p. 636-648 13 p.

Research output: Contribution to journalArticle

Smoking
Genome
Lipids
Life Style
Serum
1 Citation (Scopus)

Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension

Mehanna, M., Wang, Z., Gong, Y., McDonough, C. W., Beitelshees, A. L., Gums, J. G., Chapman, A. B., Schwartz, G. L., Bailey, K. R., Johnson, J. A., Turner, S. T. & Cooper-DeHoff, R. M., Jun 11 2019, In : American journal of hypertension. 32, 7, p. 668-675 8 p.

Research output: Contribution to journalArticle

Renin
African Americans
Biomarkers
Blood Pressure
Hypertension

β 2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies

Shahin, M. H., Rouby, N. E., Conrado, D. J., Gonzalez, D., Gong, Y., Lobmeyer, M. T., Beitelshees, A. L., Boerwinkle, E., Gums, J. G., Chapman, A., Turner, S. T., Pepine, C. J., Cooper-DeHoff, R. M. & Johnson, J. A., Jan 1 2019, In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Adrenergic Receptors
Heart Rate
Meta-Analysis
Genes
Single Nucleotide Polymorphism
2018
13 Citations (Scopus)

A comparison of manual tracing and FreeSurfer for estimating hippocampal volume over the adult lifespan

Schmidt, M. F., Storrs, J. M., Freeman, K. B., Jack, C. R. J., Turner, S. T., Griswold, M. E. & Mosley, T. H., Jan 1 2018, (Accepted/In press) In : Human Brain Mapping.

Research output: Contribution to journalArticle

Atrophy
Hippocampus
Automation
Brain
Cohort Studies

Adverse effects of long-term weight gain on microvascular endothelial function

Coutinho, T., Turner, S. T. & Kullo, I. J., Jan 1 2018, (Accepted/In press) In : Obesity Research and Clinical Practice.

Research output: Contribution to journalArticle

Hyperemia
Weight Gain
Dilatation
Waist Circumference
Adipose Tissue
6 Citations (Scopus)
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Acute Kidney Injury
Cohort Studies
Prospective Studies
2 Citations (Scopus)

Blood pressure signature genes and blood pressure response to thiazide diuretics: Results from the PEAR and PEAR-2 studies

Sá, A. C. C., Webb, A., Gong, Y., McDonough, C. W., Shahin, M. H., Datta, S., Langaee, T. Y., Turner, S. T., Beitelshees, A. L., Chapman, A. B., Boerwinkle, E., Gums, J. G., Scherer, S. E., Cooper-Dehoff, R. M., Sadee, W. & Johnson, J. A., Jun 20 2018, In : BMC Medical Genomics. 11, 1, 55.

Research output: Contribution to journalArticle

Sodium Chloride Symporter Inhibitors
Pharmacogenetics
Antihypertensive Agents
Blood Pressure
Hydrochlorothiazide
5 Citations (Scopus)

DNA methylation in the APOE genomic region is associated with cognitive function in African Americans

Liu, J., Zhao, W., Ware, E. B., Turner, S. T., Mosley, T. H. & Smith, J. A., May 8 2018, In : BMC Medical Genomics. 11, 1, 43.

Research output: Contribution to journalArticle

Apolipoproteins E
DNA Methylation
African Americans
Cognition
Methylation
3 Citations (Scopus)

Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain magnetic resonance imaging

neuroCHARGE Working Group, Jan 1 2018, In : Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

Open Access
Exome
Magnetic Resonance Imaging
Brain
Meta-Analysis
Cerebral Small Vessel Diseases
2 Citations (Scopus)

Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses)

McDonough, C. W., Magvanjav, O., Sá, A. C. C., El Rouby, N. M., Dave, C., Deitchman, A. N., Kawaguchi-Suzuki, M., Mei, W., Shen, Y., Singh, R. S. P., Solayman, M., Bailey, K. R., Boerwinkle, E., Chapman, A. B., Gums, J. G., Webb, A., Scherer, S. E., Sadee, W., Turner, S. T., Cooper-DeHoff, R. M. & 2 others, Gong, Y. & Johnson, J. A., Apr 1 2018, In : Circulation. Genomic and precision medicine. 11, 4, p. e001854

Research output: Contribution to journalArticle

Renin
Antihypertensive Agents
Blood Pressure
Single Nucleotide Polymorphism
Hydrochlorothiazide
6 Citations (Scopus)

Genome-wide association approach identified novel genetic predictors of heart rate response to β-blockers

Shahin, M. H., Conrado, D. J., Gonzalez, D., Gong, Y., Lobmeyer, M. T., Beitelshees, A. L., Boerwinkle, E., Gums, J. G., Chapman, A., Turner, S. T., Cooper-DeHoff, R. M. & Johnson, J. A., Mar 6 2018, In : Journal of the American Heart Association. 7, 5, e006463.

Research output: Contribution to journalArticle

Sorting Nexins
Heart Rate
Single Nucleotide Polymorphism
Genome
Atenolol
3 Citations (Scopus)

Genome wide association study identifies the HMGCS2 locus to be associated with chlorthalidone induced glucose increase in hypertensive patients

Singh, S., McDonough, C. W., Gong, Y., Alghamdi, W. A., Arwood, M. J., Bargal, S. A., Dumeny, L., Li, W. Y., Mehanna, M., Stockard, B., Yang, G., de Oliveira, F. A., Fredette, N. C., Shahin, M. H., Bailey, K. R., Beitelshees, A. L., Boerwinkle, E., Chapman, A. B., Gums, J. G., Turner, S. T. & 2 others, Cooper-DeHoff, R. M. & Johnson, J. A., Mar 20 2018, In : Journal of the American Heart Association. 7, 6, e007339.

Research output: Contribution to journalArticle

Chlorthalidone
Genome-Wide Association Study
Glucose
Single Nucleotide Polymorphism
Thiazides
3 Citations (Scopus)

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., Wojczynski, M. K., Männistö, S., Ngwa, J. S., Kho, M., Ahluwalia, T. S., Pervjakova, N., Houston, D. K., Bouchard, C., Huang, T., Orho-Melander, M. & 86 others, Frazier-Wood, A. C., Mook-Kanamori, D. O., Pérusse, L., Pennell, C. E., de Vries, P. S., Voortman, T., Li, O., Kanoni, S., Rose, L. M., Lehtimäki, T., Zhao, J. H., Feitosa, M. F., Luan, J., McKeown, N. M., Smith, J. A., Hansen, T., Eklund, N., Nalls, M. A., Rankinen, T., Huang, J., Hernandez, D. G., Schulz, C. A., Manichaikul, A., Li-Gao, R., Vohl, M. C., Wang, C. A., van Rooij, F. J. A., Shin, J., Kalafati, I. P., Day, F., Ridker, P. M., Kähönen, M., Siscovick, D. S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D. C., Qi, Q., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkilä, V., Wareham, N. J., Kardia, S. L. R., Pedersen, O., Jula, A., Curran, J. E., Zillikens, M. C., Viikari, J. S., Forouhi, N. G., Ordovás, J. M., Lieske, J. C., Rissanen, H., Uitterlinden, A. G., Raitakari, O. T., Kiefte-de Jong, J. C., Dupuis, J., Rotter, J. I., North, K. E., Scott, R. A., Province, M. A., Perola, M., Cupples, L. A., Turner, S. T., Sørensen, T. I. A., Salomaa, V., Liu, Y., Sung, Y. J., Qi, L., Bandinelli, S., Rich, S. S., de Mutsert, R., Tremblay, A., Oddy, W. H., Franco, O. H., Paus, T., Florez, J. C., Deloukas, P., Lyytikäinen, L. P., Chasman, D. I., Chu, A. Y. & Tanaka, T., Jul 9 2018, (Accepted/In press) In : Molecular Psychiatry. p. 1-13 13 p.

Research output: Contribution to journalArticle

Meta-Analysis
Epidemiology
Carbohydrates
Genome
Genetic Loci
5 Citations (Scopus)

Hormone therapy and urine protein excretion: A multiracial cohort study, systematic review, and meta-analysis

Kattah, A. G., Suarez, M. L. G., Milic, N., Kantarci, K. M., Zeydan, B., Mosley, T., Turner, S. T., Ware, E. B., Kardia, S. L. R. & Garovic, V. D., Jun 1 2018, In : Menopause. 25, 6, p. 625-634 10 p.

Research output: Contribution to journalReview article

Albuminuria
Meta-Analysis
Cohort Studies
Urine
Hormones
4 Citations (Scopus)

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H. & 252 others, Bartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 1 2018, In : PLoS One. 13, 6, e0198166.

Research output: Contribution to journalArticle

Blood pressure
blood pressure
ancestry
alcohols
Genes

Relationships of Clinical and Computed Tomography-Imaged Adiposity with Cognition in Middle-Aged and Older African Americans

Parker, K. G., Lirette, S. T., Deardorff, D. S., Bielak, L. F., Peyser, P. A., Carr, J. J., Terry, J. G., Fornage, M., Benjamin, E. J., Turner, S. T., Mosley, T. H., Griswold, M. E. & Windham, B. G., Mar 14 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 4, p. 492-498 7 p.

Research output: Contribution to journalArticle

Adiposity
African Americans
Cognition
Tomography
Intra-Abdominal Fat
2 Citations (Scopus)

Sphingolipid metabolic pathway impacts thiazide diuretics blood pressure response: Insights from genomics, metabolomics, and lipidomics

Shahin, M. H., Gong, Y., Frye, R. F., Rotroff, D. M., Beitelshees, A. L., Baillie, R. A., Chapman, A. B., Gums, J. G., Turner, S. T., Boerwinkle, E., Motsinger-Reif, A., Fiehn, O., Cooper-DeHoff, R. M., Han, X., Kaddurah-Daouk, R. & Johnson, J. A., Jan 1 2018, In : Journal of the American Heart Association. 7, 1, e006656.

Research output: Contribution to journalArticle

Sodium Chloride Symporter Inhibitors
Sphingolipids
Hydrochlorothiazide
Metabolomics
Genomics
68 Citations (Scopus)

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P., Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Rujescu, D., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2018, In : Nature Communications. 9, 1, 2098.

Research output: Contribution to journalArticle

Genetic Loci
loci
Cognition
Genes
genes
3 Citations (Scopus)

Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide

Singh, S., Wang, Z., Shahin, M. H., Langaee, T. Y., Gong, Y., Turner, S. T., Chapman, A. B., Gums, J. G., McDonough, C. W., Bailey, K. R., Beitelshees, A. L., Cooper-DeHoff, R. M., Scherer, S., Boerwinkle, E. & Johnson, J. A., Nov 1 2018, In : Pharmacogenetics and Genomics. 28, 11, p. 251-255 5 p.

Research output: Contribution to journalArticle

Hydrochlorothiazide
Antihypertensive Agents
Molecular Epidemiology
Pharmacogenetics
Blood Pressure
2017
2 Citations (Scopus)

Adiposity, Change in Adiposity, and Cognitive Decline in Mid- and Late Life

West, N. A., Lirette, S. T., Cannon, V. A., Turner, S. T., Mosley, T. H. & Windham, B. G., 2017, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Adiposity
Waist Circumference
Body Mass Index
African Americans
Mississippi
1 Citation (Scopus)

Association of urinary citrate excretion, pH, and net gastrointestinal alkali absorption with diet, diuretic use, and blood glucose concentration

Perinpam, M., Ware, E. B., Smith, J. A., Turner, S. T., Kardia, S. L. R. & Lieske, J. C., Oct 1 2017, In : Physiological Reports. 5, 19

Research output: Contribution to journalArticle

Alkalies
Diuretics
Citric Acid
Blood Glucose
Diet
5 Citations (Scopus)

Associations of Brain Structure With Adiposity and Changes in Adiposity in a Middle-Aged and Older Biracial Population

Windham, B. G., Lirette, S. T., Fornage, M., Benjamin, E. J., Parker, K. G., Turner, S. T., Jack, C. R. J., Griswold, M. E. & Mosley, T. H., Jun 1 2017, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 72, 6, p. 825-831 7 p.

Research output: Contribution to journalArticle

Adiposity
African Americans
Waist Circumference
Brain
Confidence Intervals
2 Citations (Scopus)

Associations of Nocturnal blood pressure with cognition by self-identified race in middle-aged and older adults: The GENOA (Genetic Epidemiology Network of Arteriopathy) study

Yano, Y., Butler, K. R., Hall, M. E., Schwartz, G. L., Knopman, D. S., Lirette, S. T., Jones, D. W., Wilson, J. G., Hall, J. E., Correa, A., Turner, S. T. & Mosley, T. H., Nov 1 2017, In : Journal of the American Heart Association. 6, 11, e007022.

Research output: Contribution to journalArticle

Molecular Epidemiology
Cognition
Blood Pressure
Trail Making Test
Linear Models
3 Citations (Scopus)

Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension

Mehanna, M., Gong, Y., Mcdonough, C. W., Beitelshees, A. L., Gums, J. G., Chapman, A. B., Schwartz, G. L., Johnson, J. A., Turner, S. T. & Cooper-Dehoff, R. M., 2017, (Accepted/In press) In : Journal of Clinical Hypertension.

Research output: Contribution to journalArticle

Chlorthalidone
Metoprolol
African Americans
Blood Pressure
Hypertension
1 Citation (Scopus)

Correction: The complex genetics of gait speed: Genome-wide metaanalysis approach [Aging, (Albany NY), 9, 1, (2017), (209-246)]doi 10.18632/aging.101151

Ben-Avraham, D., Karasik, D., Verghese, J., Lunetta, K. L., Smith, J. A., Eicher, J. D., Vered, R., Deelen, J., Arnold, A. M., Buchman, A. S., Tanaka, T., Faul, J. D., Nethander, M., Fornage, M., Adams, H. H., Matteini, A. M., Callisaya, M. L., Smith, A. V., Yu, L., De Jager, P. L. & 50 others, Evans, D. A., Gudnason, V., Hofman, A., Pattie, A., Corley, J., Launer, L. J., Knopman, D. S., Parimi, N., Turner, S. T., Bandinelli, S., Beekman, M., Gutman, D., Sharvit, L., Mooijaart, S. P., Liewald, D. C., Houwing-Duistermaat, J. J., Ohlsson, C., Moed, M., Verlinden, V. J., Mellström, D., van der Geest, J. N., Karlsson, M., Hernandez, D., McWhirter, R., Liu, Y., Thomson, R., Tranah, G. J., Uitterlinden, A. G., Weir, D. R., Zhao, W., Starr, J. M., Johnson, A. D., Arfan Ikram, M., Bennett, D. A., Cummings, S. R., Deary, I. J., Harris, T. B., Kardia, S. L. R., Mosley, T. H., Srikanth, V. K., Windham, B. G., Newman, A. B., Walston, J. D., Davies, G., Evans, D. S., Slagboom, E. P., Ferrucci, L., Kiel, D. P., Murabito, J. M. & Atzmon, G., Jul 1 2017, In : Aging. 9, 7, p. 1844-1846 3 p.

Research output: Contribution to journalComment/debate

Genome
Small Nucleolar RNA
Long Noncoding RNA
Genes
Small Nuclear RNA
2 Citations (Scopus)

Data on the relation between renal biomarkers and measured glomerular filtration rate

Pottel, H., Dubourg, L., Schaeffner, E., Eriksen, B. O., Melsom, T., Lamb, E. J., Rule, A. D., Turner, S. T., Glassock, R. J., De Souza, V., Selistre, L., Goffin, K., Pauwels, S., Mariat, C., Flamant, M., Bevc, S., Delanaye, P. & Ebert, N., Oct 1 2017, In : Data in Brief. 14, p. 763-772 10 p.

Research output: Contribution to journalArticle

diagnostic
normalization
16 Citations (Scopus)

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

BIOS Consortium, Dec 7 2017, In : American Journal of Human Genetics. 101, 6, p. 888-902 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Blood Pressure
Methylation
Gene Expression
Mendelian Randomization Analysis
60 Citations (Scopus)

Estimating glomerular filtration rate for the full age spectrum from serum creatinine and cystatin C

Pottel, H., Delanaye, P., Schaeffner, E., Dubourg, L., Eriksen, B. O., Melsom, T., Lamb, E. J., Rule, A. D., Turner, S. T., Glassock, R. J., De Souza, V., Selistre, L., Goffin, K., Pauwels, S., Mariat, C., Flamant, M. & Ebert, N., Mar 1 2017, In : Nephrology Dialysis Transplantation. 32, 3, p. 497-507 11 p.

Research output: Contribution to journalArticle

Cystatin C
Glomerular Filtration Rate
Creatinine
Serum
Biomarkers
2 Citations (Scopus)

Genetic variants associated with uncontrolled blood pressure on thiazide diuretic/β-blocker combination therapy in the PEAR (Pharmacogenomic Evaluation Of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) trials

Magvanjav, O., Gong, Y., McDonough, C. W., Chapman, A. B., Turner, S. T., Gums, J. G., Bailey, K. R., Boerwinkle, E., Beitelshees, A. L., Tanaka, T., Kubo, M., Pepine, C. J., Cooper-DeHoff, R. M. & Johnson, J. A., Nov 1 2017, In : Journal of the American Heart Association. 6, 11, e006522.

Research output: Contribution to journalArticle

trandolapril
Sodium Chloride Symporter Inhibitors
Pharmacogenetics
Verapamil
Antihypertensive Agents
15 Citations (Scopus)

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

Salvi, E., Wang, Z., Rizzi, F., Gong, Y., McDonough, C. W., Padmanabhan, S., Hiltunen, T. P., Lanzani, C., Zaninello, R., Chittani, M., Bailey, K. R., Sarin, A. P., Barcella, M., Melander, O., Chapman, A. B., Manunta, P., Kontula, K. K., Glorioso, N., Cusi, D., Dominiczak, A. F. & 5 others, Johnson, J. A., Barlassina, C., Boerwinkle, E., Cooper-DeHoff, R. M. & Turner, S. T., Jan 1 2017, In : Hypertension. 69, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

Hydrochlorothiazide
Meta-Analysis
Genome
Blood Pressure
Antihypertensive Agents
3 Citations (Scopus)

Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated with Thiazide Diuretics Blood Pressure Response

Shahin, M. H., Sá, A. C., Webb, A., Gong, Y., Langaee, T., McDonough, C. W., Riva, A., Beitleshees, A. L., Chapman, A. B., Gums, J. G., Turner, S. T., Boerwinkle, E., Scherer, S. E., Sadee, W., Cooper-Dehoff, R. M. & Johnson, J. A., Feb 1 2017, In : Circulation: Cardiovascular Genetics. 10, 1, 001404.

Research output: Contribution to journalArticle

Sodium Chloride Symporter Inhibitors
Genome
Blood Pressure
Hydrochlorothiazide
Single Nucleotide Polymorphism
7 Citations (Scopus)

Modeling the Causal Role of DNA Methylation in the Association between Cigarette Smoking and Inflammation in African Americans: A 2-Step Epigenetic Mendelian Randomization Study

Jhun, M. A., Smith, J. A., Ware, E. B., Kardia, S. L. R., Mosley, T. H., Turner, S. T., Peyser, P. A. & Park, S. K., Nov 15 2017, In : American Journal of Epidemiology. 186, 10, p. 1149-1158 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Random Allocation
varespladib methyl
Epigenomics
African Americans
5 Citations (Scopus)

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A., Gorski, M., McMahon, G. M., Xu, H., Chang, Y. P. C., Van Der Most, P. J., Navis, G., Nolte, I. M., De Borst, M. H., Zhang, W., Lehne, B., Loh, M., Tan, S. T., Boerwinkle, E., Grams, M. E., Sekula, P., Li, M., Wilmot, B., Moon, J. G., Scheet, P. & 86 others, Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

Osmolar Concentration
Meta-Analysis
Water
Sodium
Hypernatremia
3 Citations (Scopus)

Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH

Canales, B. K., Smith, J. A., Weiner, I. D., Ware, E. B., Zhao, W., Kardia, S. L. R., Curhan, G. C., Turner, S. T., Perinpam, M. & Lieske, J. C., Jan 1 2017, In : Kidney International Reports. 2, 6, p. 1111-1121 11 p.

Research output: Contribution to journalArticle

Ammonia
Single Nucleotide Polymorphism
Urine
Kidney
Genes
16 Citations (Scopus)

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

Li, M., Li, Y., Weeks, O., Mijatovic, V., Teumer, A., Huffman, J. E., Tromp, G., Fuchsberger, C., Gorski, M., Lyytikäinen, L. P., Nutile, T., Sedaghat, S., Sorice, R., Tin, A., Yang, Q., Ahluwalia, T. S., Arking, D. E., Bihlmeyer, N. A., Böger, C. A., Carroll, R. J. & 136 others, Chasman, D. I., Cornelis, M. C., Dehghan, A., Faul, J. D., Feitosa, M. F., Gambaro, G., Gasparini, P., Giulianini, F., Heid, I., Huang, J., Imboden, M., Jackson, A. U., Jeff, J., Jhun, M. A., Katz, R., Kifley, A., Kilpeläinen, T. O., Kumar, A., Laakso, M., Li-Gao, R., Lohman, K., Lu, Y., Mägi, R., Malerba, G., Mihailov, E., Mohlke, K. L., Mook-Kanamori, D. O., Robino, A., Ruderfer, D., Salvi, E., Schick, U. M., Schulz, C. A., Smith, A. V., Smith, J. A., Traglia, M., Yerges-Armstrong, L. M., Zhao, W., Goodarzi, M. O., Kraja, A. T., Liu, C., Wessel, J., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bottinger, E. P., Braga, D., Brandslund, I., Brody, J. A., Campbell, A., Carey, D. J., Christensen, C., Coresh, J., Crook, E., Curhan, G. C., Cusi, D., De Boer, I. H., De Vries, A. P. J., Denny, J. C., Devuyst, O., Dreisbach, A. W., Endlich, K., Esko, T., Franco, O. H., Fulop, T., Gerhard, G. S., Glümer, C., Gottesman, O., Grarup, N., Gudnason, V., Hansen, T., Harris, T. B., Hayward, C., Hocking, L., Hofman, A., Hu, F. B., Husemoen, L. L. N., Jackson, R. D., Jørgensen, T., Jørgensen, M. E., Kähönen, M., Kardia, S. L. R., König, W., Kooperberg, C., Kriebel, J., Launer, L. J., Lauritzen, T., Lehtimäki, T., Levy, D., Linksted, P., Linneberg, A., Liu, Y., Loos, R. J. F., Lupo, A., Meisinger, C., Melander, O., Metspalu, A., Mitchell, P., Nauck, M., Nürnberg, P., Orho-Melander, M., Parsa, A., Pedersen, O., Peters, A., Peters, U., Polasek, O., Porteous, D., Probst-Hensch, N. M., Psaty, B. M., Qi, L., Raitakari, O. T., Reiner, A. P., Rettig, R., Ridker, P. M., Rivadeneira, F., Rossouw, J. E., Schmidt, F., Siscovick, D., Soranzo, N., Strauch, K., Toniolo, D., Turner, S. T., Uitterlinden, A. G., Ulivi, S., Velayutham, D., Völker, U., Völzke, H., Waldenberger, M., Wang, J. J., Weir, D. R., Witte, D., Kuivaniemi, H., Fox, C. S., Franceschini, N., Goessling, W., Köttgen, A. & Chu, A. Y., Mar 1 2017, In : Journal of the American Society of Nephrology. 28, 3, p. 981-994 14 p.

Research output: Contribution to journalArticle

Exome
Kidney
Genes
ras Guanine Nucleotide Exchange Factors
Rho Guanine Nucleotide Exchange Factors
15 Citations (Scopus)

The association between cigarette smoking and inflammation: The Genetic Epidemiology Network of Arteriopathy (GENOA) study

Tibuakuu, M., Kamimura, D., Kianoush, S., DeFilippis, A. P., Al Rifai, M., Reynolds, L. M., White, W. B., Butler, K. R., Mosley, T. H., Turner, S. T., Kullo, I. J., Hall, M. E. & Blaha, M. J., Sep 1 2017, In : PLoS One. 12, 9, e0184914.

Research output: Contribution to journalArticle

Molecular Epidemiology
smoking (habit)
Biomarkers
Tobacco Products
epidemiology
6 Citations (Scopus)

The complex genetics of gait speed: Genome-wide meta-analysis approach

Ben-Avraham, D., Karasik, D., Verghese, J., Lunetta, K. L., Smith, J. A., Eicher, J. D., Vered, R., Deelen, J., Arnold, A. M., Buchman, A. S., Tanaka, T., Faul, J. D., Nethander, M., Fornage, M., Adams, H. H., Matteini, A. M., Callisaya, M. L., Smith, A. V., Yu, L., De Jager, P. L. & 50 others, Evans, D. A., Gudnason, V., Hofman, A., Pattie, A., Corley, J., Launer, L. J., Knopman, D. S., Parimi, N., Turner, S. T., Bandinelli, S., Beekman, M., Gutman, D., Sharvit, L., Mooijaart, S. P., Liewald, D. C., Houwing-Duistermaat, J. J., Ohlsson, C., Moed, M., Verlinden, V. J., Mellström, D., van der Geest, J. N., Karlsson, M., Hernandez, D., McWhirter, R., Liu, Y., Thomson, R., Tranah, G. J., Uitterlinden, A. G., Weir, D. R., Zhao, W., Starr, J. M., Johnson, A. D., Arfan Ikram, M., Bennett, D. A., Cummings, S. R., Deary, I. J., Harris, T. B., Sharon, S. L., Mosley, T. H., Srikanth, V. K., Windham, B. G., Newman, A. B., Walston, J. D., Davies, G., Evans, D. S., Slagboom, E. P., Ferrucci, L., Kiel, D. P., Murabito, J. M. & Atzmon, G., 2017, In : Aging. 9, 1, p. 209-246 38 p.

Research output: Contribution to journalArticle

Meta-Analysis
Genome
Single Nucleotide Polymorphism
Multifactorial Inheritance
Walking Speed
6 Citations (Scopus)

The diagnostic value of rescaled renal biomarkers serum creatinine and serum cystatin C and their relation with measured glomerular filtration rate

Pottel, H., Dubourg, L., Schaeffner, E., Eriksen, B. O., Melsom, T., Lamb, E. J., Rule, A. D., Turner, S. T., Glassock, R. J., De Souza, V., Selistre, L., Goffin, K., Pauwels, S., Mariat, C., Flamant, M., Bevc, S., Delanaye, P. & Ebert, N., Aug 1 2017, In : Clinica Chimica Acta. 471, p. 164-170 7 p.

Research output: Contribution to journalArticle

Cystatin C
Biomarkers
Glomerular Filtration Rate
Creatinine
Kidney
1 Citation (Scopus)

Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics

Sá, A. C. C., Webb, A., Gong, Y., McDonough, C. W., Datta, S., Langaee, T. Y., Turner, S. T., Beitelshees, A. L., Chapman, A. B., Boerwinkle, E., Gums, J. G., Scherer, S. E., Cooper-Dehoff, R. M., Sadee, W. & Johnson, J. A., Dec 1 2017, In : Scientific Reports. 7, 1, 16068.

Research output: Contribution to journalArticle

Sodium Chloride Symporter Inhibitors
Gene Expression Profiling
Antihypertensive Agents
Blood Pressure
Pharmacogenetics
2016
11 Citations (Scopus)

A genetic response score for hydrochlorothiazide use

Shahin, M. H., Gong, Y., McDonough, C. W., Rotroff, D. M., Beitelshees, A. L., Garrett, T. J., Gums, J. G., Motsinger-Reif, A., Chapman, A. B., Turner, S. T., Boerwinkle, E., Frye, R. F., Fiehn, O., Cooper-Dehoff, R. M., Kaddurah-Daouk, R. & Johnson, J. A., Sep 1 2016, In : Hypertension. 68, 3, p. 621-629 9 p.

Research output: Contribution to journalArticle

Hydrochlorothiazide
Blood Pressure
Metabolomics
Alleles
Antihypertensive Agents