Stephen Maxted Ansell, MD, PhD

  • 23318 Citations
  • 81 Scopus h-Index
1989 …2020

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2011

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts

Hodge, L. S., Elsawa, S. F., Grote, D. M., Price-Troska, T. L., Asmann, Y. W., Fonseca, R., Gertz, M. A., Witzig, T. E., Novak, A. J. & Ansell, S. M., Jun 1 2011, In : Blood cancer journal. 1, 6, e24.

Research output: Contribution to journalArticle

13 Scopus citations

Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas

Witzig, T. E., Tang, H., Micallef, I. N. M., Ansell, S. M., Link, B. K., Inwards, D. J., Porrata, L. F., Johnston, P. B., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Thompson, C. A., Allmer, C., Maurer, M. J., Gupta, M., Weiner, G., Hohl, R., Kurtin, P. J., Ding, H., Loegering, D. & 4 others, Schneider, P., Peterson, K., Habermann, T. M. & Kaufmann, S. H., Nov 3 2011, In : Blood. 118, 18, p. 4882-4889 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Predicting PBSC harvest failure using circulating CD34 levels: Developing target-based cutoff points for early intervention

Sinha, S., Gastineau, D., Micallef, I., Hogan, W., Ansell, S., Buadi, F., Dingli, D., Dispenzieri, A., Gertz, M., Greiner, C., Hayman, S., Inwards, D., Johnston, P., Lacy, M., Litzow, M., Porrata, L., Winters, J. L. & Kumar, S., Jul 1 2011, In : Bone Marrow Transplantation. 46, 7, p. 943-949 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Soluble IL-2Rα facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Manske, M. K., Witzig, T. E., Novak, A. J. & Ansell, S. M., Sep 8 2011, In : Blood. 118, 10, p. 2809-2820 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: A multicenter study of 204 skin biopsies

Wada, D. A., Law, M. E., Hsi, E. D., Dicaudo, D. J., Ma, L., Lim, M. S., De Souza, A., Comfere, N. I., Weenig, R. H., MacOn, W. R., Erickson, L. A., Özsan, N., Ansell, S. M., Dogan, A. & Feldman, A. L., Apr 1 2011, In : Modern Pathology. 24, 4, p. 596-605 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 1 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

128 Scopus citations

The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I. N. M., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Sep 1 2011, In : Leukemia. 25, 9, p. 1502-1509 8 p.

Research output: Contribution to journalArticle

121 Scopus citations
2010

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

Hildebrand, J. M., Luo, Z., Manske, M. K., Price-Troska, T., Ziesmer, S. C., Lin, W., Hostager, B. S., Slager, S. L., Witzig, T. E., Ansell, S. M., Cerhan, J. R., Bishop, G. A. & Novak, A. J., Nov 22 2010, In : Journal of Experimental Medicine. 207, 12, p. 2569-2579 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma

Younes, A., Vose, J. M., Zelenetz, A. D., Smith, M. R., Burris, H. A., Ansell, S. M., Klein, J., Halpern, W., Miceli, R., Kumm, E., Fox, N. L. & Czuczman, M. S., Dec 7 2010, In : British journal of cancer. 103, 12, p. 1783-1787 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

A phase II study of 153Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

Dispenzieri, A., Wiseman, G. A., Lacy, M. Q., Hayman, S. R., Kumar, S. K., Buadi, F., Dingli, D., Laumann, K. M., Allred, J., Geyer, S. M., Litzow, M. R., Gastineau, D. A., Inwards, D. J., Micallef, I. N., Ansell, S. M., Porrata, L., Elliott, M. A., Johnston, P. B., Hogan, W. J. & Gertz, M. A., Jun 1 2010, In : American journal of hematology. 85, 6, p. 409-413 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma

Johnston, P. B., Inwards, D. J., Colgan, J. P., Laplant, B. R., Kabat, B. F., Habermann, T. M., Micallef, I. N., Porrata, L. F., Ansell, S. M., Reeder, C. B., Roy, V. & Witzig, T. E., May 1 2010, In : American journal of hematology. 85, 5, p. 320-324 5 p.

Research output: Contribution to journalArticle

178 Scopus citations

Autologous stem cell transplant for immunoglobulin light chain amyloidosis: A status report

Gertz, M. A., Lacy, M. Q., Dispenzieri, A., Hayman, S. R., Kumar, S. K., Dingli, D., Ansell, S. M., Gastineau, D. A., Inwards, D. J., Johnston, P. B., Litzow, M. R., Micallef, I. N. M., Porrata, L. F., Leung, N., Hogan, W. J. & Buadi, F. K., Dec 1 2010, In : Leukemia and Lymphoma. 51, 12, p. 2181-2187 7 p.

Research output: Contribution to journalArticle

78 Scopus citations
11 Scopus citations

Comparison of error rates in single-arm versus randomized phase II cancer clinical trials

Tang, H., Foster, N. R., Grothey, A., Ansell, S. M., Goldberg, R. M. & Sargent, D. J., Apr 10 2010, In : Journal of Clinical Oncology. 28, 11, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma

Kelly, J. L., Novak, A. J., Fredericksen, Z. S., Liebow, M., Ansell, S. M., Dogan, A., Wang, A. H., Witzig, T. E., Call, T. G., Kay, N. E., Habermann, T. M., Slager, S. L. & Cerhan, J. R., Nov 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 11, p. 2847-2858 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

IgM multiple myeloma: Disease definition, prognosis, and differentiation from Waldenstrom's macroglobulinemia

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Aspitia, A. M., Ansell, S., Kyle, R. & Mikhael, J., Nov 1 2010, In : American journal of hematology. 85, 11, p. 853-855 3 p.

Research output: Contribution to journalArticle

55 Scopus citations
15 Scopus citations
43 Scopus citations
24 Scopus citations

Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory waldenström macroglobulinemia

Ghobrial, I. M., Gertz, M., LaPlant, B., Camoriano, J., Hayman, S., Lacy, M., Chuma, S., Harris, B., Leduc, R., Rourke, M., Ansell, S. M., DeAngelo, D., Dispenzieri, A., Bergsagel, L., Reeder, C., Anderson, K. C., Richardson, P. G., Treon, S. P. & Witzig, T. E., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Phase i trial of autologous hematopoietic SCT with escalating doses of topotecan combined with CY and carboplatin in patients with relapsed or persistent ovarian or primary peritoneal carcinoma

Litzow, M. R., Peethambaram, P. P., Safgren, S. L., Keeney, G. L., Ansell, S. M., Dispenzieri, A., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Inwards, D. J., Lacy, M. Q., Micallef, I. N. M., Porrata, L. F., Lingle, W. L., Hartmann, L. C., Frost, M. H., Barrette, B. A., Long, H. J., Suman, V. J., Reid, J. M. & 2 others, Ames, M. M. & Kaufmann, S. H., Jan 1 2010, In : Bone Marrow Transplantation. 45, 3, p. 490-497 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Statin use and prognosis in patients with diffuse large B-cell lymphoma and follicular lymphoma in the rituximab era

Nowakowski, G. S., Maurer, M. J., Habermann, T. M., Ansell, S. M., Macon, W. R., Ristow, K. M., Allmer, C., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jan 20 2010, In : Journal of Clinical Oncology. 28, 3, p. 412-417 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma

Drake, M. T., Maurer, M. J., Link, B. K., Habermann, T. M., Ansell, S. M., Micallef, I. N., Kelly, J. L., Macon, W. R., Nowakowski, G. S., Inwards, D. J., Johnston, P. B., Singh, R. J., Allmer, C., Slager, S. L., Weiner, G. J., Witzig, T. E. & Cerhan, J. R., Sep 20 2010, In : Journal of Clinical Oncology. 28, 27, p. 4191-4198 8 p.

Research output: Contribution to journalArticle

165 Scopus citations
2009
41 Scopus citations

B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders

Wilcox, R. A., Feldman, A. L., Wada, D. A., Yang, Z. Z., Comfere, N. I., Dong, H., Kwon, E. D., Novak, A. J., Markovic, S. N., Pittelkow, M. R., Witzig, T. E. & Ansell, S. M., 2009, In : Blood. 114, 10, p. 2149-2158 10 p.

Research output: Contribution to journalArticle

141 Scopus citations

Cytokines in the microenvironment of Waldenström's macroglobulinemia

Elsawa, S. & Ansell, S., Jan 1 2009, In : Clinical Lymphoma and Myeloma. 9, 1, p. 43-45 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Genetic variation in B-cell-activating factor is associated with an increased risk of developing B-cell non-Hodgkin lymphoma

Novak, A. J., Slager, S. L., Fredericksen, Z. S., Wang, A. H., Manske, M. M., Ziesmer, S., Liebow, M., Macon, W. R., Dillon, S. R., Witzig, T. E., Cerhan, J. R. & Ansell, S. M., May 15 2009, In : Cancer research. 69, 10, p. 4217-4224 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
129 Scopus citations

Intraepithelial Effector (CD3+)/Regulatory (FoxP3+) T-Cell Ratio Predicts a Clinical Outcome of Human Colon Carcinoma

Sinicrope, F. A., Rego, R. L., Ansell, S. M., Knutson, K. L., Foster, N. R. & Sargent, D. J., Oct 2009, In : Gastroenterology. 137, 4, p. 1270-1279 10 p.

Research output: Contribution to journalArticle

189 Scopus citations

Malignant B cells skew the balance of regulatory T cells and T H17 cells in B-cell non-Hodgkin's lymphoma

Yang, Z. Z., Novak, A. J., Ziesmer, S. C., Witzig, T. E. & Ansell, S. M., Jul 1 2009, In : Cancer research. 69, 13, p. 5522-5530 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells

Wilcox, R. A., Wada, D. A., Ziesmer, S. C., Elsawa, S. F., Comfere, N. I., Dietz, A. B., Novak, A. J., Witzig, T. E., Feldman, A. L., Pittelkow, M. R. & Ansell, S. M., 2009, In : Blood. 114, 14, p. 2936-2944 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma

Ansell, S. M., Hurvitz, S. A., Koenig, P. A., LaPlant, B. R., Kabat, B. F., Fernando, D., Habermann, T. M., Inwards, D. J., Verma, M., Yamada, R., Erlichman, C., Lowy, I. & Timmerman, J. M., Oct 15 2009, In : Clinical Cancer Research. 15, 20, p. 6446-6453 8 p.

Research output: Contribution to journalArticle

206 Scopus citations

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes

Cerhan, J. R., Novak, A. J., Fredericksen, Z. S., Wang, A. H., Liebow, M., Call, T. G., Dogan, A. M., Witzig, T. E., Ansell, S. M., Habermann, T. M., Kay, N. E. & Slager, S. L., Jun 1 2009, In : British journal of haematology. 145, 5, p. 614-623 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Serum BLyS levels increase after rituximab as initial therapy in patients with follicular grade 1 non-Hodgkin lymphoma

Ansell, S. M., Novak, A. J., Ziesmer, S., Price-Troska, T., Laplant, B., Dillon, S. R. & Witzig, T. E., Feb 1 2009, In : American journal of hematology. 84, 2, p. 71-73 3 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

A polymorphism in the complement component C1qA correlates with prolonged response following rituximab therapy of follicular lymphoma

Racila, E., Link, B. K., Weng, W. K., Witzig, T. E., Ansell, S., Maurer, M. J., Huang, J., Dahle, C., Halwani, A., Levy, R. & Werner, G. J., Oct 15 2008, In : Clinical Cancer Research. 14, 20, p. 6697-6703 7 p.

Research output: Contribution to journalArticle

114 Scopus citations

A role for IFN-λ1 in multiple myeloma B cell growth

Novak, A. J., Grote, D. M., Ziesmer, S. C., Rajkumar, V., Doyle, S. E. & Ansell, S. M., Jan 1 2008, In : Leukemia. 22, 12, p. 2240-2246 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Autologous stem cell transplant in 716 patients with multiple myeloma: Low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative

Gertz, M. A., Ansell, S. M., Dingli, D., Dispenzieri, A., Buadi, F. K., Elliott, M. A., Gastineau, D. A., Hayman, S. R., Hogan, W. J., Inwards, D. J., Johnston, P. B., Kumar, S., Lacy, M. Q., Leung, N., Micallef, I. N. M., Porrata, L. F., Schafer, B. A., Wolf, R. C. & Litzow, M. R., Oct 2008, In : Mayo Clinic proceedings. 83, 10, p. 1131-1135 5 p.

Research output: Contribution to journalArticle

71 Scopus citations

CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia

Elsawa, S. F., Novak, A. J., Grote, D., Konopleva, M., Andreeff, M., Witzig, T. E. & Ansell, S. M., Dec 1 2008, In : Leukemia Research. 32, 12, p. 1895-1902 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Early Lymphocyte Recovery Predicts Superior Survival after Autologous Stem Cell Transplantation in Non-Hodgkin Lymphoma: A Prospective Study

Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I. N., Johnston, P. B., Gastineau, D. A., Litzow, M. R., Winters, J. L. & Markovic, S. N., Jul 1 2008, In : Biology of Blood and Marrow Transplantation. 14, 7, p. 807-816 10 p.

Research output: Contribution to journalArticle

101 Scopus citations
16 Scopus citations

Genetic variation in tumor necrosis factor and the nuclear factor-κB canonical pathway and risk of non-Hodgkin's lymphoma

Cerhan, J. R., Liu-Mares, W., Fredericksen, Z. S., Novak, A. J., Cunningham, J. M., Kay, N. E., Dogan, A. M., Liebow, M., Wang, A. H., Call, T. G., Habermann, T. M., Ansell, S. M. & Slager, S. L., Nov 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 11, p. 3161-3169 9 p.

Research output: Contribution to journalArticle

61 Scopus citations
19 Scopus citations

High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system

Gill, P., Litzow, M., Buckner, J., Arndt, C., Moynihan, T., Christianson, T., Ansell, S. & Galanis, E., Apr 15 2008, In : Cancer. 112, 8, p. 1805-1811 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

Habermann, T. M., Wang, S. S., Maurer, M. J., Morton, L. M., Lynch, C. F., Ansell, S. M., Hartge, P., Severson, R. K., Rothman, N., Davis, S., Geyer, S. M., Cozen, W., Chanock, S. J. & Cerhan, J. R., Oct 1 2008, In : Blood. 112, 7, p. 2694-2702 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Long-term outcome of allogeneic stem cell transplantation in chronic lymphocytic leukemia: Analysis after a minimum follow-up of 5 years

Malhotra, P., Hogan, W. J., Litzow, M. R., Elliott, M. A., Gastineau, D. A., Ansell, S. M., Dispenzieri, A., Gertz, M. A., Hayman, S. R., Inwards, D. J., Lacy, M. Q., Micallef, I. N., Porrata, L. F. & Tefferi, A., Sep 29 2008, In : Leukemia and Lymphoma. 49, 9, p. 1724-1730 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Long-term results of the treatment of patients with mantle cell lymphoma with cladribine (2-CDA) alone (95-80-53) or 2-CDA and rituximab (N0189) in the North Central Cancer Treatment Group

Inwards, D. J., Fishkin, P. A. S., Hillman, D. W., Brown, D. W., Ansell, S. M., Kurtin, P. J., Fonseca, R., Morton, R. F., Veeder, M. H. & Witzig, T. E., Jul 1 2008, In : Cancer. 113, 1, p. 108-116 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: A phase 2 trial in the North Central Cancer Treatment Group

Ansell, S. M., Inwards, D. J., Rowland, K. M., Flynn, P. J., Morton, R. F., Moore, D. F., Kaufmann, S. H., Ghobrial, I., Kurtin, P. J., Maurer, M., Allmer, C. & Witzig, T. E., Aug 1 2008, In : Cancer. 113, 3, p. 508-514 7 p.

Research output: Contribution to journalArticle

181 Scopus citations

Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome

Dispenzieri, A., Lacy, M. Q., Hayman, S. R., Kumar, S. K., Buadi, F., Dingli, D., Litzow, M. R., Gastineau, D. A., Inwards, D. J., Elliott, M. A., Micallef, I. N., Ansell, S. M., Hogan, W. J., Porrata, L. F., Johnston, P. A., Afessa, B., Bryce, A., Kyle, R. A. & Gertz, M. A., May 1 2008, In : European Journal of Haematology. 80, 5, p. 397-406 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma

Ansell, S. M., Witzig, T. E., Inwards, D. J., Porrata, L. F., Ythier, A., Ferrande, L., Nestorov, I., DeVries, T., Dillon, S. R., Hausman, D. & Novak, A. J., Feb 15 2008, In : Clinical Cancer Research. 14, 4, p. 1105-1110 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

The value of [18f]fluorodeoxyglucose positron emission tomography/computed tomography in extranodal natural killer/T-cell lymphoma

Karantanis, D., Subramaniam, R. M., Peller, P. J., Lowe, V. J., Durski, J. M., Collins, D. A., Georgiou, E., Ansell, S. M. & Wiseman, G. A., Apr 2008, In : Clinical Lymphoma and Myeloma. 8, 2, p. 94-99 6 p.

Research output: Contribution to journalArticle

38 Scopus citations