Stephen Maxted Ansell, MD, PhD

  • 22276 Citations
  • 80 Scopus h-Index
1976 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2013

Progress in the initial management of Hodgkin's Lymphoma

Marri, P. R. & Ansell, S. M., Aug 1 2013, In : Transfusion and Apheresis Science. 49, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
150 Scopus citations

Response assessment in Waldenström macroglobulinaemia: Update from the VIth International Workshop

Owen, R. G., Kyle, R. A., Stone, M. J., Rawstron, A. C., Leblond, V., Merlini, G., Garcia-Sanz, R., Ocio, E. M., Morra, E., Morel, P., Anderson, K. C., Patterson, C. J., Munshi, N. C., Tedeschi, A., Joshua, D. E., Kastritis, E., Terpos, E., Ghobrial, I. M., Leleu, X., Gertz, M. A. & 4 others, Ansell, S. M., Morice, W. G., Kimby, E. & Treon, S. P., Jan 1 2013, In : British journal of haematology. 160, 2, p. 171-176 6 p.

Research output: Contribution to journalArticle

121 Scopus citations

Soluble and Membrane-Bound TGF-β-Mediated Regulation of Intratumoral T Cell Differentiation and Function in B-Cell Non-Hodgkin Lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Xiu, B., Yates, N. R., Secreto, F. J., Hodge, L. S., Witzig, T. E., Novak, A. J. & Ansell, S. M., Mar 15 2013, In : PloS one. 8, 3, e59456.

Research output: Contribution to journalArticle

28 Scopus citations

Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor

Hussain, S., Feldman, A. L., Das, C., Ziesmer, S. C., Ansell, S. M. & Galardy, P. J., Mar 1 2013, In : Molecular and cellular biology. 33, 6, p. 1188-1197 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Waldenström's macroglobulinemia: Treatment approaches for newly diagnosed and relapsed disease

Hodge, L. S. & Ansell, S. M., Aug 1 2013, In : Transfusion and Apheresis Science. 49, 1, p. 19-23 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012
41 Scopus citations
17 Scopus citations

Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Nowakowski, G. S., Nikcevich, D. A., Nelson, G. D., Yang, Z., Grote, D. M., Ziesmer, S. C., Silberstein, P. T., Erlichman, C. & Witzig, T. E., May 2012, In : Leukemia. 26, 5, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia

Vitale, L. A., He, L. Z., Thomas, L. J., Widger, J., Weidlick, J., Crocker, A., O'Neill, T., Storey, J., Glennie, M. J., Grote, D. M., Ansell, S. M., Marsh, H. & Keler, T., Jul 15 2012, In : Clinical Cancer Research. 18, 14, p. 3812-3821 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C., Cruz-Gordillo, P., Knoechel, B., Asmann, Y. W., Slager, S. L., Novak, A. J., Dogan, A., Ansell, S. M., Link, B. K., Zou, L., Gould, J., Saksena, G., Stransky, N., Rangel-Escareño, C., Fernandez-Lopez, J. C. & 14 others, Hidalgo-Miranda, A., Melendez-Zajgla, J., Hernández-Lemus, E., Schwarz-Cruz y Celis, A., Imaz-Rosshandler, I., Ojesina, A. I., Jung, J., Pedamallu, C. S., Lander, E. S., Habermann, T. M., Cerhan, J. R., Shipp, M. A., Getz, G. & Golub, T. R., Mar 6 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3879-3884 6 p.

Research output: Contribution to journalArticle

590 Scopus citations

Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma

Kelly, J. L., Drake, M. T., Fredericksen, Z. S., Asmann, Y. W., Liebow, M., Shanafelt, T. D., Feldman, A. L., Ansell, S. M., Macon, W. R., Herr, M. M., Wang, A. H., Nowakowski, G. S., Call, T. G., Habermann, T. M., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jul 1 2012, In : Cancer Causes and Control. 23, 7, p. 1017-1029 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
28 Scopus citations

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

Vasmatzis, G., Johnson, S. H., Knudson, R. A., Ketterling, R. P., Braggio, E., Fonseca, R., Viswanatha, D. S., Law, M. E., Kip, N. S., Özsan, N., Grebe, S. K., Frederick, L. A., Eckloff, B. W., Thompson, E. A., Kadin, M. E., Milosevic, D., Porcher, J. C., Asmann, Y. W., Smith, D. I., Kovtun, I. V. & 3 others, Ansell, S. M., Dogan, A. & Feldman, A. L., Sep 13 2012, In : Blood. 120, 11, p. 2280-2289 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma

Charbonneau, B., Maurer, M. J., Fredericksen, Z. S., Zent, C. S., Link, B. K., Novak, A. J., Ansell, S. M., Weiner, G. J., Wang, A. H., Witzig, T. E., Dogan, A., Slager, S. L., Habermann, T. M. & Cerhan, J. R., Sep 1 2012, In : American journal of hematology. 87, 9, p. 880-885 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hodgkin lymphoma: 2012 update on diagnosis, risk-stratification, and management

Ansell, S. M., Dec 1 2012, In : American journal of hematology. 87, 12, p. 1096-1103 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Niki, T., Hirashima, M., Novak, A. J., Witzig, T. E. & Ansell, S. M., Apr 2 2012, In : Journal of Clinical Investigation. 122, 4, p. 1271-1282 12 p.

Research output: Contribution to journalArticle

150 Scopus citations

IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia

Hodge, L. S., Ziesmer, S. C., Yang, Z. Z., Secreto, F. J., Gertz, M. A., Novak, A. J. & Ansell, S. M., Nov 1 2012, In : Blood. 120, 18, p. 3774-3782 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): A single-center experience

D'Souza, A., Lacy, M., Gertz, M., Kumar, S., Buadi, F., Hayman, S., Dingli, D., Zeldenrust, S., Kyle, R., Ansell, S., Inwards, D., Johnston, P., Micallef, I., Porrata, L., Litzow, M., Gastineau, D., Hogan, W. & Dispenzieri, A., Jul 5 2012, In : Blood. 120, 1, p. 56-62 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma

Ramakrishnan, V., Ansell, S., Haug, J., Grote, D., Kimlinger, T., Stenson, M., Timm, M., Wellik, L., Halling, T., Rajkumar, S. V. & Kumar, S., Feb 1 2012, In : Leukemia. 26, 2, p. 340-348 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Peripheral blood lymphocyte/monocyte ratio at diagnosis and survival in classical Hodgkin's lymphoma

Porrata, L. F., Ristow, K., Colgan, J. P., Habermann, T. M., Witzig, T. E., Inwards, D. J., Ansell, S. M., Micallef, I. N., Johnston, P. B., Nowakowski, G. S., Thompson, C. & Markovic, S. N., Feb 1 2012, In : Haematologica. 97, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

134 Scopus citations
53 Scopus citations

Positron emission tomographic scans in lymphoma: Convention and controversy

Ansell, S. M. & Armitage, J. O., Jun 2012, In : Mayo Clinic proceedings. 87, 6, p. 571-580 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pretreatment circulating serum cytokines associated with follicular and diffuse large B-cell lymphoma: A clinic-based case-control study

Charbonneau, B., Maurer, M. J., Ansell, S. M., Slager, S. L., Fredericksen, Z. S., Ziesmer, S. C., Macon, W. R., Habermann, T. M., Witzig, T. E., Link, B. K., Cerhan, J. R. & Novak, A. J., Dec 1 2012, In : Cytokine. 60, 3, p. 882-889 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: Results from the InterLymph consortium

Nieters, A., Conde, L., Slager, S. L., Brooks-Wilson, A., Morton, L., Skibola, D. R., Novak, A. J., Riby, J., Ansell, S. M., Halperin, E., Shanafelt, T. D., Agana, L., Wang, A. H., De Roos, A. J., Severson, R. K., Cozen, W., Spinelli, J., Butterbach, K., Becker, N., De Sanjose, S. & 23 others, Benavente, Y., Cocco, P., Staines, A., Maynadié, M., Foretova, L., Boffetta, P., Brennan, P., Lan, Q., Zhang, Y., Zheng, T., Purdue, M., Armstrong, B., Kricker, A., Vajdic, C. M., Grulich, A., Smith, M. T., Bracci, P. M., Chanock, S. J., Hartge, P., Cerhan, J. R., Wang, S. S., Rothman, N. & Skibola, C. F., Nov 29 2012, In : Blood. 120, 23, p. 4645-44648 40004 p.

Research output: Contribution to journalArticle

19 Scopus citations

Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma

Younes, A., Gopal, A. K., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Ramchandren, R., Bartlett, N. L., Cheson, B. D., De Vos, S., Forero-Torres, A., Moskowitz, C. H., Connors, J. M., Engert, A., Larsen, E. K., Kennedy, D. A., Sievers, E. L. & Chen, R., Jun 20 2012, In : Journal of Clinical Oncology. 30, 18, p. 2183-2189 7 p.

Research output: Contribution to journalArticle

894 Scopus citations

t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth

Ansell, S. M., Akasaka, T., McPhail, E., Manske, M., Braggio, E., Price-Troska, T., Ziesmer, S., Secreto, F., Fonseca, R., Gupta, M., Law, M., Witzig, T. E., Dyer, M. J. S., Dogan, A., Cerhan, J. R. & Novak, A. J., Nov 8 2012, In : Blood. 120, 19, p. 3949-3957 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The absolute monocyte count is associated with overall survival in patients newly diagnosed with follicular lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I. N. M., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Apr 1 2012, In : Leukemia and Lymphoma. 53, 4, p. 575-580 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

The tumor microenvironment in follicular lymphoma

Yang, Z. Z. & Ansell, S. M., Dec 1 2012, In : Clinical Advances in Hematology and Oncology. 10, 12, p. 810-818 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011
4 Scopus citations

A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma

Witzig, T. E., Reeder, C. B., Laplant, B. R., Gupta, M., Johnston, P. B., Micallef, I. N., Porrata, L. F., Ansell, S. M., Colgan, J. P., Jacobsen, E. D., Ghobrial, I. M. & Habermann, T. M., Feb 2011, In : Leukemia. 25, 2, p. 341-347 7 p.

Research output: Contribution to journalArticle

238 Scopus citations
68 Scopus citations

Brentuximab vedotin: Delivering an antimitotic drug to activated lymphoma cells

Ansell, S. M., Jan 1 2011, In : Expert Opinion on Investigational Drugs. 20, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma

Burington, B., Yue, P., Shi, X., Advani, R., Lau, J. T., Tan, J., Stinson, S., Stinson, J., Januario, T., De Vos, S., Ansell, S., Forero-Torres, A., Fedorowicz, G., Yang, T. T. C., Elkins, K., Du, C., Mohan, S., Yu, N., Modrusan, Z., Seshagiri, S. & 9 others, Yu, S. F., Pandita, A., Koeppen, H., French, D., Polson, A. G., Offringa, R., Whiting, N., Ebens, A. & Dornan, D., Mar 16 2011, In : Science translational medicine. 3, 74, 74ra22.

Research output: Contribution to journalArticle

27 Scopus citations

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

Elsawa, S. F., Novak, A. J., Ziesmer, S. C., Almada, L. L., Hodge, L. S., Grote, D. M., Witzig, T. E., Fernandez-Zapico, M. E. & Ansell, S. M., Nov 17 2011, In : Blood. 118, 20, p. 5540-5549 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Design and validity of a clinic-based case-control study on the molecular epidemiology of lymphoma

Cerhan, J. R., Fredericksen, Z. S., Wang, A. H., Habermann, T. M., Kay, N. E., Macon, W. R., Cunningham, J. M., Shanafelt, T. D., Ansell, S. M., Call, T. G., Witzig, T. E., Slager, S. L. & Liebow, M., Jun 13 2011, In : International Journal of Molecular Epidemiology and Genetics. 2, 2, p. 95-113 19 p.

Research output: Contribution to journalArticle

31 Scopus citations

Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing

Feldman, A. L., Dogan, A., Smith, D. I., Law, M. E., Ansell, S. M., Johnson, S. H., Porcher, J. C., Özsan, N., Wieben, E. D., Eckloff, B. W. & Vasmatzis, G., Jan 20 2011, In : Blood. 117, 3, p. 915-919 5 p.

Research output: Contribution to journalArticle

187 Scopus citations

Elevated serum free light chains are associated with event-free and overall survival in two independent cohorts of patients with diffuse large B-cell lymphoma

Maurer, M. J., Micallef, I. N. M., Cerhan, J. R., Katzmann, J. A., Link, B. K., Colgan, J. P., Habermann, T. M., Inwards, D. J., Markovic, S. N., Ansell, S. M., Porrata, L. F., Johnston, P. B., Nowakowski, G. S., Thompson, C. A., Gupta, M., Syrbu, S. I., Kurtin, P. J., Macon, W. R., Nikcevich, D. A. & Witzig, T. E., Apr 20 2011, In : Journal of Clinical Oncology. 29, 12, p. 1620-1626 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Elevated serum free light chains are associated with inferior event free and overall survival in Hodgkin lymphoma

Thompson, C. A., Maurer, M. J., Cerhan, J. R., Katzmann, J. A., Ansell, S. M., Habermann, T. M., Macon, W. R., Weiner, G. J., Link, B. K. & Witzig, T. E., Dec 1 2011, In : American journal of hematology. 86, 12, p. 998-1000 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Establishment and characterization of a novel Waldenström macroglobulinemia cell line, MWCL-1

Hodge, L. S., Novak, A. J., Grote, D. M., Braggio, E., Ketterling, R. P., Manske, M. K., Price Troska, T. L., Ziesmer, S. C., Fonseca, R., Witzig, T. E., Morice, W. G., Gertz, M. A. & Ansell, S. M., May 12 2011, In : Blood. 117, 19, p. e190-e197

Research output: Contribution to journalArticle

29 Scopus citations

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment

Elsawa, S. F., Almada, L. L., Ziesmer, S. C., Novak, A. J., Witzig, T. E., Ansell, S. M. & Fernandez-Zapico, M. E., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21524-21534 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Jak/stat pathway in Waldenström's macroglobulinemia

Hodge, L. S. & Ansell, S. M., Feb 1 2011, In : Clinical Lymphoma, Myeloma and Leukemia. 11, 1, p. 112-114 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: Phase i study

Nowakowski, G. S., Laplant, B., Habermann, T. M., Rivera, C. E., MacOn, W. R., Inwards, D. J., Micallef, I. N., Johnston, P. B., Porrata, L. F., Ansell, S. M., Klebig, R. R., Reeder, C. B. & Witzig, T. E., Dec 1 2011, In : Leukemia. 25, 12, p. 1877-1881 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Low risk of symptomatic venous thromboembolic events during growth factor administration for PBSC mobilization

Naina, H. V., Pruthi, R. K., Inwards, D. J., Dingli, D., Litzow, M. R., Ansell, S. M., William, H. J., Dispenzieri, A., Buadi, F. K., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Hayman, S. R., Johnston, P. B., Lacy, M. Q., Micallef, I. N., Porrata, L. F. & Kumar, S., Feb 1 2011, In : Bone Marrow Transplantation. 46, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts

Hodge, L. S., Elsawa, S. F., Grote, D. M., Price-Troska, T. L., Asmann, Y. W., Fonseca, R., Gertz, M. A., Witzig, T. E., Novak, A. J. & Ansell, S. M., Jun 1 2011, In : Blood cancer journal. 1, 6, e24.

Research output: Contribution to journalArticle

13 Scopus citations

Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas

Witzig, T. E., Tang, H., Micallef, I. N. M., Ansell, S. M., Link, B. K., Inwards, D. J., Porrata, L. F., Johnston, P. B., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Thompson, C. A., Allmer, C., Maurer, M. J., Gupta, M., Weiner, G., Hohl, R., Kurtin, P. J., Ding, H., Loegering, D. & 4 others, Schneider, P., Peterson, K., Habermann, T. M. & Kaufmann, S. H., Nov 3 2011, In : Blood. 118, 18, p. 4882-4889 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Predicting PBSC harvest failure using circulating CD34 levels: Developing target-based cutoff points for early intervention

Sinha, S., Gastineau, D., Micallef, I., Hogan, W., Ansell, S., Buadi, F., Dingli, D., Dispenzieri, A., Gertz, M., Greiner, C., Hayman, S., Inwards, D., Johnston, P., Lacy, M., Litzow, M., Porrata, L., Winters, J. L. & Kumar, S., Jul 1 2011, In : Bone Marrow Transplantation. 46, 7, p. 943-949 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Soluble IL-2Rα facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Manske, M. K., Witzig, T. E., Novak, A. J. & Ansell, S. M., Sep 8 2011, In : Blood. 118, 10, p. 2809-2820 12 p.

Research output: Contribution to journalArticle

72 Scopus citations

Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: A multicenter study of 204 skin biopsies

Wada, D. A., Law, M. E., Hsi, E. D., Dicaudo, D. J., Ma, L., Lim, M. S., De Souza, A., Comfere, N. I., Weenig, R. H., MacOn, W. R., Erickson, L. A., Özsan, N., Ansell, S. M., Dogan, A. & Feldman, A. L., Apr 1 2011, In : Modern Pathology. 24, 4, p. 596-605 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 1 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

123 Scopus citations