Stephen Maxted Ansell, MD, PhD

  • 22202 Citations
  • 80 Scopus h-Index
1976 …2020

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2011

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment

Elsawa, S. F., Almada, L. L., Ziesmer, S. C., Novak, A. J., Witzig, T. E., Ansell, S. M. & Fernandez-Zapico, M. E., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21524-21534 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Identifying patients with follicular lymphoma who are likely to benefit from an idiotype vaccine

Ansell, S. M. & Suman, V. J., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20, p. 2748-2749 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Innate immune B cells gone bad

Ansell, S. M., Nov 7 2011, In : Oncology. 25, 12

Research output: Contribution to journalArticle

Jak/stat pathway in Waldenström's macroglobulinemia

Hodge, L. S. & Ansell, S. M., Feb 1 2011, In : Clinical Lymphoma, Myeloma and Leukemia. 11, 1, p. 112-114 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: Phase i study

Nowakowski, G. S., Laplant, B., Habermann, T. M., Rivera, C. E., MacOn, W. R., Inwards, D. J., Micallef, I., Johnston, P. B., Porrata, L. F., Ansell, S. M., Klebig, R. R., Reeder, C. B. & Witzig, T. E., Dec 2011, In : Leukemia. 25, 12, p. 1877-1881 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Low risk of symptomatic venous thromboembolic events during growth factor administration for PBSC mobilization

Naina, H. V., Pruthi, R. K., Inwards, D. J., Dingli, D. M., Litzow, M. R., Ansell, S. M., Hogan, W., Dispenzieri, A., Buadi, F. K., Elliott, M. A., Gastineau, D. A., Gertz, M., Hayman, S. R., Johnston, P. B., Lacy, M., Micallef, I., Porrata, L. F. & Kumar, S. K., Feb 2011, In : Bone Marrow Transplantation. 46, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts

Hodge, L. S., Elsawa, S. F., Grote, D. M., Price-Troska, T. L., Asmann, Y., Fonseca, R., Gertz, M., Witzig, T. E., Novak, A. J. & Ansell, S. M., Jun 2011, In : Blood Cancer Journal. 1, 6, e24.

Research output: Contribution to journalArticle

13 Scopus citations

Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas

Witzig, T. E., Tang, H., Micallef, I., Ansell, S. M., Link, B. K., Inwards, D. J., Porrata, L. F., Johnston, P. B., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Thompson, C. A., Allmer, C., Maurer, M. J., Gupta, M., Weiner, G., Hohl, R., Kurtin, P. J., Ding, H., Loegering, D. & 4 others, Schneider, P., Peterson, K., Habermann, T. M. & Kaufmann, S. H., Nov 3 2011, In : Blood. 118, 18, p. 4882-4889 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Novel therapeutic agents for B-cell lymphoma: Developing rational combinations

Reeder, C. B. & Ansell, S. M., Feb 3 2011, In : Blood. 117, 5, p. 1453-1462 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Predicting PBSC harvest failure using circulating CD34 levels: Developing target-based cutoff points for early intervention

Sinha, S., Gastineau, D., Micallef, I., Hogan, W., Ansell, S. M., Buadi, F., Dingli, D. M., Dispenzieri, A., Gertz, M., Greiner, C., Hayman, S., Inwards, D., Johnston, P. B., Lacy, M., Litzow, M. R., Porrata, L., Winters, J. L. & Kumar, S. K., Jul 2011, In : Bone Marrow Transplantation. 46, 7, p. 943-949 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Programmed death 1 is expressed in cutaneous infiltrates of mycosis fungoides and Sézary syndrome

Wada, D. A., Wilcox, R. A., Harrington, S. M., Kwon, E. D., Ansell, S. M. & Comfere, N. I., Mar 2011, In : American Journal of Hematology. 86, 3, p. 325-327 3 p.

Research output: Contribution to journalArticle

36 Scopus citations

Soluble IL-2Rα facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Manske, M. K., Witzig, T. E., Novak, A. J. & Ansell, S. M., Sep 8 2011, In : Blood. 118, 10, p. 2809-2820 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: A multicenter study of 204 skin biopsies

Wada, D. A., Law, M. E., Hsi, E. D., Dicaudo, D. J., Ma, L., Lim, M. S., De Souza, A., Comfere, N. I., Weenig, R. H., MacOn, W. R., Erickson, L. A., Özsan, N., Ansell, S. M., Dogan, A. & Feldman, A. L., Apr 2011, In : Modern Pathology. 24, 4, p. 596-605 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Sep 2011, In : Leukemia. 25, 9, p. 1502-1509 8 p.

Research output: Contribution to journalArticle

116 Scopus citations

The definition of IgM multiple myeloma

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Moreno Aspitia, A., Ansell, S. M., Kyle, R. & Mikhael, J. R., Aug 2011, In : American Journal of Hematology. 86, 8, p. 718-719 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012
41 Scopus citations
17 Scopus citations

Beyond targeting malignant B cells

Ansell, S. M., Jul 2012, In : The Lancet Oncology. 13, 7, p. 657-658 2 p.

Research output: Contribution to journalArticle

Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Nowakowski, G. S., Nikcevich, D. A., Nelson, G. D., Yang, Z., Grote, D. M., Ziesmer, S. C., Silberstein, P. T., Erlichman, C. & Witzig, T. E., May 2012, In : Leukemia. 26, 5, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia

Vitale, L. A., He, L. Z., Thomas, L. J., Widger, J., Weidlick, J., Crocker, A., O'Neill, T., Storey, J., Glennie, M. J., Grote, D. M., Ansell, S. M., Marsh, H. & Keler, T., Jul 15 2012, In : Clinical Cancer Research. 18, 14, p. 3812-3821 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C., Cruz-Gordillo, P., Knoechel, B., Asmann, Y., Slager, S. L., Novak, A. J., Dogan, A., Ansell, S. M., Link, B. K., Zou, L., Gould, J., Saksena, G., Stransky, N., Rangel-Escareño, C., Fernandez-Lopez, J. C. & 14 others, Hidalgo-Miranda, A., Melendez-Zajgla, J., Hernández-Lemus, E., Schwarz-Cruz y Celis, A., Imaz-Rosshandler, I., Ojesina, A. I., Jung, J., Pedamallu, C. S., Lander, E. S., Habermann, T. M., Cerhan, J. R., Shipp, M. A., Getz, G. & Golub, T. R., Mar 6 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3879-3884 6 p.

Research output: Contribution to journalArticle

590 Scopus citations

Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma

Kelly, J. L., Drake, M. M., Fredericksen, Z. S., Asmann, Y., Liebow, M., Shanafelt, T. D., Feldman, A. L., Ansell, S. M., Macon, W. R., Herr, M. M., Wang, A. H., Nowakowski, G. S., Call, T. G., Habermann, T. M., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jul 2012, In : Cancer Causes and Control. 23, 7, p. 1017-1029 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
28 Scopus citations

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

Vasmatzis, G., Johnson, S. H., Knudson, R. A., Ketterling, R. P., Braggio, E. D., Fonseca, R., Viswanatha, D. S., Law, M. E., Kip, N. S., Özsan, N., Grebe, S. K., Frederick, L. A., Eckloff, B. W., Thompson, E. A., Kadin, M. E., Milosevic, D., Porcher, J. C., Asmann, Y., Smith, D. I., Kovtun, I. V. & 3 others, Ansell, S. M., Dogan, A. & Feldman, A. L., Sep 13 2012, In : Blood. 120, 11, p. 2280-2289 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma

Charbonneau, B., Maurer, M. J., Fredericksen, Z. S., Zent, C. S., Link, B. K., Novak, A. J., Ansell, S. M., Weiner, G. J., Wang, A. H., Witzig, T. E., Dogan, A., Slager, S. L., Habermann, T. M. & Cerhan, J. R., Sep 2012, In : American Journal of Hematology. 87, 9, p. 880-885 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Hodgkin lymphoma: 2012 update on diagnosis, risk-stratification, and management

Ansell, S. M., Dec 2012, In : American Journal of Hematology. 87, 12, p. 1096-1103 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Niki, T., Hirashima, M., Novak, A. J., Witzig, T. E. & Ansell, S. M., Apr 2 2012, In : Journal of Clinical Investigation. 122, 4, p. 1271-1282 12 p.

Research output: Contribution to journalArticle

149 Scopus citations

IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia

Hodge, L. S., Ziesmer, S. C., Yang, Z. Z., Secreto, F. J., Gertz, M., Novak, A. J. & Ansell, S. M., Nov 1 2012, In : Blood. 120, 18, p. 3774-3782 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): A single-center experience

D'Souza, A., Lacy, M., Gertz, M., Kumar, S. K., Buadi, F., Hayman, S., Dingli, D. M., Zeldenrust, S., Kyle, R., Ansell, S. M., Inwards, D., Johnston, P. B., Micallef, I., Porrata, L., Litzow, M. R., Gastineau, D., Hogan, W. & Dispenzieri, A., Jul 5 2012, In : Blood. 120, 1, p. 56-62 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Molecular pathogenesis of Waldenström's macroglobulinemia

Braggio, E. D., Philipsborn, C., Novak, A. J., Hodge, L., Ansell, S. M. & Fonseca, R., Sep 1 2012, In : Haematologica. 97, 9, p. 1281-1290 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma

Ramakrishnan, V., Ansell, S. M., Haug, J., Grote, D., Kimlinger, T., Stenson, M., Timm, M., Wellik, L., Halling, T., Rajkumar, S. V. & Kumar, S. K., Feb 2012, In : Leukemia. 26, 2, p. 340-348 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Peripheral blood lymphocyte/monocyte ratio at diagnosis and survival in classical Hodgkin's lymphoma

Porrata, L. F., Ristow, K., Colgan, J. P., Habermann, T. M., Witzig, T. E., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Nowakowski, G. S., Thompson, C. A. & Markovic, S. N., Feb 1 2012, In : Haematologica. 97, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

134 Scopus citations
53 Scopus citations

Positron emission tomographic scans in lymphoma: Convention and controversy

Ansell, S. M. & Armitage, J. O., 2012, In : Mayo Clinic Proceedings. 87, 6, p. 571-580 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pretreatment circulating serum cytokines associated with follicular and diffuse large B-cell lymphoma: A clinic-based case-control study

Charbonneau, B., Maurer, M. J., Ansell, S. M., Slager, S. L., Fredericksen, Z. S., Ziesmer, S. C., Macon, W. R., Habermann, T. M., Witzig, T. E., Link, B. K., Cerhan, J. R. & Novak, A. J., Dec 2012, In : Cytokine. 60, 3, p. 882-889 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: Results from the InterLymph consortium

Nieters, A., Conde, L., Slager, S. L., Brooks-Wilson, A., Morton, L., Skibola, D. R., Novak, A. J., Riby, J., Ansell, S. M., Halperin, E., Shanafelt, T. D., Agana, L., Wang, A. H., De Roos, A. J., Severson, R. K., Cozen, W., Spinelli, J., Butterbach, K., Becker, N., De Sanjose, S. & 23 others, Benavente, Y., Cocco, P., Staines, A., Maynadié, M., Foretova, L., Boffetta, P., Brennan, P., Lan, Q., Zhang, Y., Zheng, T., Purdue, M., Armstrong, B., Kricker, A., Vajdic, C. M., Grulich, A., Smith, M. T., Bracci, P. M., Chanock, S. J., Hartge, P., Cerhan, J. R., Wang, S. S., Rothman, N. & Skibola, C. F., Nov 29 2012, In : Blood. 120, 23, p. 4645-44648 40004 p.

Research output: Contribution to journalArticle

19 Scopus citations

Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma

Younes, A., Gopal, A. K., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Ramchandren, R., Bartlett, N. L., Cheson, B. D., De Vos, S., Forero-Torres, A., Moskowitz, C. H., Connors, J. M., Engert, A., Larsen, E. K., Kennedy, D. A., Sievers, E. L. & Chen, R., Jun 20 2012, In : Journal of Clinical Oncology. 30, 18, p. 2183-2189 7 p.

Research output: Contribution to journalArticle

891 Scopus citations

Stem cell transplant for Waldenström macroglobulinemia: An underutilized technique

Gertz, M., Reeder, C. B., Kyle, R. A. & Ansell, S. M., Sep 2012, In : Bone Marrow Transplantation. 47, 9, p. 1147-1153 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth

Ansell, S. M., Akasaka, T., McPhail, E., Manske, M., Braggio, E. D., Price-Troska, T., Ziesmer, S., Secreto, F., Fonseca, R., Gupta, M., Law, M., Witzig, T. E., Dyer, M. J. S., Dogan, A., Cerhan, J. R. & Novak, A. J., Nov 8 2012, In : Blood. 120, 19, p. 3949-3957 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The absolute monocyte count is associated with overall survival in patients newly diagnosed with follicular lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Apr 2012, In : Leukemia and Lymphoma. 53, 4, p. 575-580 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

The B7 Homologues and their Receptors in Hematologic Malignancies

Wilcox, R. A., Ansell, S. M., Lim, M. S., Zou, W. & Chen, L., Jun 2012, In : European Journal of Haematology. 88, 6, p. 465-475 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

The tumor microenvironment in follicular lymphoma

Yang, Z. Z. & Ansell, S. M., Dec 2012, In : Clinical Advances in Hematology and Oncology. 10, 12, p. 810-818 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

A phase I/II trial of reduced intensity allogeneic hematopoietic cell transplant for hematologic malignancies using cladribine, thiotepa and rabbit antithymocyte globulin

Larsen, J. T., Hogan, W., Micallef, I., Dispenzieri, A., Gertz, M., Inwards, D. J., Tun, H. W., Roy, V., Geyer, S. M., Allred, J. B., Wu, W., Ansell, S. M., Elliott, M. A., Tefferi, A., Porrata, L. F., Gastineau, D. A., Lacy, M. & Litzow, M. R., Aug 2013, In : Leukemia and Lymphoma. 54, 8, p. 1713-1718 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A phase I trial of immunostimulatory CpG 7909 oligodeoxynucleotide and 90yttrium ibritumomab tiuxetan radioimmunotherapy for relapsed B-cell non-Hodgkin lymphoma

Witzig, T. E., Wiseman, G. A., Maurer, M. J., Habermann, T. M., Micallef, I., Nowakowski, G. S., Ansell, S. M., Colgan, J. P., Inwards, D. J., Porrata, L. F., Link, B. K., Zent, C. S., Johnston, P. B., Shanafelt, T. D., Allmer, C., Asmann, Y., Gupta, M., Ballas, Z. K., Smith, B. J. & Weiner, G. J., Jul 2013, In : American Journal of Hematology. 88, 7, p. 589-593 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Bowel perforation in intestinal lymphoma: Incidence and clinical features

Vaidya, R., Habermann, T. M., Donohue, J. H., Ristow, K. M., Maurer, M. J., Macon, W. R., Colgan, J. P., Inwards, D. J., Ansell, S. M., Porrata, L. F., Micallef, I., Johnston, P. B., Markovic, S. N., Thompson, C. A., Nowakowski, G. S. & Witzig Dr., T. E., Sep 2013, In : Annals of Oncology. 24, 9, p. 2439-2443 5 p., mdt188.

Research output: Contribution to journalArticle

48 Scopus citations

Brentuximab vedotin combined with ABVD or AVD for patients with newly diagnosed Hodgkin's lymphoma: A phase 1, open-label, dose-escalation study

Younes, A., Connors, J. M., Park, S. I., Fanale, M., O'Meara, M. M., Hunder, N. N., Huebner, D. & Ansell, S. M., Dec 2013, In : The Lancet Oncology. 14, 13, p. 1348-1356 9 p.

Research output: Contribution to journalArticle

185 Scopus citations

CD4+CD25+FOXP3+ malignant T cells in Sézary syndrome are not necessarily functional regulatory T cells

Wada, D. A., Pittelkow, M. R., Comfere, N. I., Gibson, L. E., Ansell, S. M. & Wilcox, R. A., Sep 2013, In : Journal of the American Academy of Dermatology. 69, 3, p. 485-489 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
22 Scopus citations

Cost-Effectiveness Analysis of a Risk-Adapted Algorithm of Plerixafor Use for Autologous Peripheral Blood Stem Cell Mobilization

Micallef, I., Sinha, S., Gastineau, D. A., Wolf, R., Inwards, D. J., Gertz, M., Hayman, S. R., Hogan, W., Johnston, P. B., Lacy, M., Ansell, S. M., Buadi, F., Dingli, D. M., Dispenzieri, A., Litzow, M. R., Porrata, L. F., Winters, J. L. & Kumar, S. K., Jan 2013, In : Biology of Blood and Marrow Transplantation. 19, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

58 Scopus citations