Stephen Maxted Ansell, MD, PhD

  • 21180 Citations
  • 78 Scopus h-Index
1976 …2019
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Research Output 1983 2019

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2016
2 Citations (Scopus)

FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: A meta-analysis on 1134 patients from two prospective cohorts

Ghesquières, H., Larrabee, B. R., Haioun, C., Link, B. K., Verney, A., Slager, S. L., Ketterer, N., Ansell, S. M., Delarue, R., Maurer, M. J., Fitoussi, O., Habermann, T. M., Peyrade, F., Dogan, A., Molina, T. J., Novak, A. J., Tilly, H., Cerhan, J. R. & Salles, G., 2016, (Accepted/In press) In : Hematological Oncology.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Meta-Analysis
Disease-Free Survival
Single Nucleotide Polymorphism
Survival
136 Citations (Scopus)

Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma

Chen, R., Gopal, A. K., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Connors, J. M., Engert, A., Larsen, E. K., Huebner, D., Fong, A. & Younes, A., Sep 22 2016, In : Blood. 128, 12, p. 1562-1566 5 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Refractory materials
Durability
Survival
Stem cells
8 Citations (Scopus)

Follicular lymphoma tregs have a distinct transcription profile impacting their migration and retention in the malignant lymph node

Nedelkovska, H., Rosenberg, A. F., Hilchey, S. P., Hyrien, O., Burack, W. R., Quataert, S. A., Baker, C. M., Azadniv, M., Welle, S. L., Ansell, S. M., Kim, M. & Bernstein, S. H., May 1 2016, In : PLoS One. 11, 5, e0155347.

Research output: Contribution to journalArticle

Chemokine CXCL13
Interleukin-16
L-Selectin
Follicular Lymphoma
T-cells
26 Citations (Scopus)

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Machiela, M. J., Lan, Q., Slager, S. L., Vermeulen, R. C. H., Teras, L. R., Camp, N. J., Cerhan, J. R., Spinelli, J. J., Wang, S. S., Nieters, A., Vijai, J., Yeager, M., Wang, Z., Ghesquières, H., McKay, J., Conde, L., de Bakker, P. I. W., Cox, D. G., Burdett, L., Monnereau, A. & 100 others, Flowers, C. R., De Roos, A. J., Brooks-Wilson, A. R., Giles, G. G., Melbye, M., Gu, J., Jackson, R. D., Kane, E., Purdue, M. P., Vajdic, C. M., Albanes, D., Kelly, R. S., Zucca, M., Bertrand, K. A., Zeleniuch-Jacquotte, A., Lawrence, C., Hutchinson, A., Zhi, D., Habermann, T. M., Link, B. K., Novak, A. J., Dogan, A., Asmann, Y., Liebow, M., Thompson, C. A., Ansell, S. M., Witzig, T. E., Tilly, H., Haioun, C., Molina, T. J., Hjalgrim, H., Glimelius, B., Adami, H. O., Roos, G., Bracci, P. M., Riby, J., Smith, M. T., Holly, E. A., Cozen, W., Hartge, P., Morton, L. M., Severson, R. K., Tinker, L. F., North, K. E., Becker, N., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., Staines, A., Lightfoot, T., Crouch, S., Smith, A., Roman, E., Ryan Diver, W., Offit, K., Zelenetz, A., Klein, R. J., Villano, D. J., Zheng, T., Zhang, Y., Holford, T. R., Turner, J., Southey, M. C., Clavel, J., Virtamo, J., Weinstein, S., Riboli, E., Vineis, P., Kaaks, R., Boeing, H., Tjønneland, A., Angelucci, E., Di Lollo, S., Rais, M., De Vivo, I., Giovannucci, E., Kraft, P., Huang, J., Ma, B., Ye, Y., Chiu, B. C. H., Liang, L., Park, J. H., Chung, C. C., Weisenburger, D. D., Fraumeni, J. F., Salles, G., Glenn, M., Cannon-Albright, L., Curtin, K., Wu, X., Smedby, K. E., de Sanjose, S., Skibola, C. F., Berndt, S. I., Birmann, B. M., Chanock, S. J. & Rothman, N., Apr 15 2016, In : Human Molecular Genetics. 25, 8, p. 1663-1676 14 p., ddw027.

Research output: Contribution to journalArticle

Telomere
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
1 Citation (Scopus)

Glancing at the complex biology of T-cells through the microenvironment of Hodgkin lymphoma*

Villasboas Bisneto, J. J. C. . & Ansell, S. M., Oct 28 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-3 3 p.

Research output: Contribution to journalArticle

Cellular Microenvironment
Hodgkin Disease
T-Lymphocytes
9 Citations (Scopus)

Hodgkin lymphoma: MOPP chemotherapy to PD-1 blockade and beyond

Ansell, S. M., Jan 1 2016, In : American Journal of Hematology. 91, 1, p. 109-112 4 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Drug Therapy
Disease Management
Neoplasms
Radiotherapy
48 Citations (Scopus)

Hodgkin lymphoma: 2016 update on diagnosis, risk-stratification, and management

Ansell, S. M., Apr 1 2016, In : American Journal of Hematology. 91, 4, p. 434-442 9 p.

Research output: Contribution to journalArticle

Risk Management
Hodgkin Disease
Transplants
Drug Therapy
Radiotherapy
2 Citations (Scopus)

How to select the frontline treatment for a patient with peripheral T-cell lymphoma

Ansell, S. M., Apr 2 2016, In : Leukemia and Lymphoma. 57, 4, p. 783-788 6 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Lymphoproliferative Disorders
Stem Cell Transplantation
Combination Drug Therapy
Radiotherapy
2 Citations (Scopus)

Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop

Houot, R., Gaulard, P., Schreiber, R., Mellman, I., Lambotte, O., Coulie, P. G., Fest, T., Korman, A., Levy, R., Shipp, M., Tarte, K., Kohrt, H., Marabelle, A., Ansell, S. M., Watier, H., van Elsas, A., Balakumaran, A., Arce Vargas, F., Quezada, S. A., Salles, G. & 1 others, Olive, D., Jul 2 2016, In : OncoImmunology. 5, 7, e1186323.

Research output: Contribution to journalArticle

Lymphoma
Education
Antibodies
45 Citations (Scopus)

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Luchtel, R., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
RNA Sequence Analysis
T-cells
Gene Fusion
Fusion reactions
19 Citations (Scopus)

Large b-cell transformation in nodular lymphocyte-predominant hodgkin lymphoma: 40-year experience from a single institution

Kenderian, S., Habermann, T. M., Macon, W. R., Ristow, K. M., Ansell, S. M., Colgan, J. P., Johnston, P. B., Inwards, D. J., Markovic, S. N., Micallef, I., Thompson, C. A., Porrata, L. F., Martenson, J. A., Witzig, T. E. & Nowakowski, G. S., Apr 21 2016, In : Blood. 127, 16, p. 1960-1966 7 p.

Research output: Contribution to journalArticle

Lymphocytes
Hodgkin Disease
Lymphoma, Large B-Cell, Diffuse
Chemotherapy
Cells
15 Citations (Scopus)

Lymphoplasmacytic Lymphoma With a Non-IgM Paraprotein Shows Clinical and Pathologic Heterogeneity and May Harbor MYD88 L265P Mutations

King, R., Gonsalves, W., Ansell, S. M., Greipp, P. T., Frederick, L. A., Viswanatha, D. S., He, R., Kyle, R. A., Gertz, M., Kapoor, P., Morice, W. G. & Howard, M. T., Jun 1 2016, In : American Journal of Clinical Pathology. 145, 6, p. 843-851 9 p.

Research output: Contribution to journalArticle

Paraproteins
Waldenstrom Macroglobulinemia
Lymphoma
Mutation
Bone Marrow
357 Citations (Scopus)

Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

Younes, A., Santoro, A., Shipp, M., Zinzani, P. L., Timmerman, J. M., Ansell, S. M., Armand, P., Fanale, M., Ratanatharathorn, V., Kuruvilla, J., Cohen, J. B., Collins, G., Savage, K. J., Trneny, M., Kato, K., Farsaci, B., Parker, S. M., Rodig, S., Roemer, M. G. M., Ligon, A. H. & 1 others, Engert, A., Sep 1 2016, In : The Lancet Oncology. 17, 9, p. 1283-1294 12 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Hodgkin Disease
Safety
Advisory Committees
cAC10-vcMMAE
10 Citations (Scopus)
Programmed Cell Death 1 Receptor
Hodgkin Disease
Stem Cells
Transplants
Patient Safety
361 Citations (Scopus)

Nivolumab in patients with relapsed or refractory hematologic malignancy: Preliminary results of a phase ib study

Lesokhin, A. M., Ansell, S. M., Armand, P., Scott, E. C., Halwani, A., Gutierrez, M., Millenson, M. M., Cohen, A. D., Schuster, S. J., Lebovic, D., Dhodapkar, M., Avigan, D., Chapuy, B., Ligon, A. H., Freeman, G. J., Rodig, S. J., Cattry, D., Zhu, L., Grosso, J. F., Brigid Bradley Garelik, M. & 3 others, Shipp, M. A., Borrello, I. & Timmerman, J., Aug 10 2016, In : Journal of Clinical Oncology. 34, 23, p. 2698-2704 7 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
T-Cell Lymphoma
B-Cell Lymphoma
Peripheral T-Cell Lymphoma
Mycosis Fungoides
16 Citations (Scopus)

Personalized risk prediction for event-free survival at 24 months in patients with diffuse large B-cell lymphoma

Maurer, M. J., Jais, J. P., Ghesquières, H., Witzig, T. E., Hong, F., Haioun, C., Thompson, C. A., Thieblemont, C., Micallef, I., Porrata, L. F., Ribrag, V., Nowakowski, G. S., Casasnovas, O., Bologna, S., Morschhauser, F., Morrison, V. A., Peterson, B. A., Macon, W. R., Copie-Bergman, C., Feldman, A. L. & 13 others, Syrbu, S. I., Kurtin, P. J., Gascoyne, R. D., Li, H., Allmer, C., Kahl, B. S., Ansell, S. M., Slager, S. L., Link, B. K., Salles, G., Habermann, T. M., Tilly, H. & Cerhan, J. R., Feb 1 2016, In : American Journal of Hematology. 91, 2, p. 179-184 6 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Disease-Free Survival
Survival
Anthracyclines
Datasets
101 Citations (Scopus)

Refinement of the Lugano Classification lymphoma response criteria in the era of immunomodulatory therapy

Cheson, B. D., Ansell, S. M., Schwartz, L., Gordon, L. I., Advani, R., Jacene, H. A., Hoos, A., Barrington, S. F. & Armand, P., Nov 24 2016, In : Blood. 128, 21, p. 2489-2496 8 p.

Research output: Contribution to journalArticle

Immunomodulation
Lymphoma
Tumors
Imaging techniques
Histology
20 Citations (Scopus)

Role of the tumor microenvironment in mature B-cell lymphoid malignancies

Fowler, N. H., Cheah, C. Y., Gascoyne, R. D., Gribben, J., Neelapu, S. S., Ghia, P., Bollard, C., Ansell, S. M., Curran, M., Wilson, W. H., O’Brien, S., Grant, C., Little, R., Zenz, T., Nastoupil, L. J. & Dunleavy, K., Apr 30 2016, In : Haematologica. 101, 5, p. 531-540 10 p.

Research output: Contribution to journalArticle

Cellular Microenvironment
Tumor Microenvironment
B-Lymphocytes
B-Cell Lymphoma
Neoplasms
42 Citations (Scopus)
Hodgkin Disease
Stem Cells
Transplants
Stem Cell Transplantation
Graft vs Host Disease
29 Citations (Scopus)

The landscape of new drugs in lymphoma

Younes, A., Ansell, S. M., Fowler, N., Wilson, W., de Vos, S., Seymour, J., Advani, R., Forero, A., Morschhauser, F., Kersten, M. J., Tobinai, K., Zinzani, P. L., Zucca, E., Abramson, J. & Vose, J., Dec 29 2016, (Accepted/In press) In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalArticle

Lymphoma
Pharmaceutical Preparations
Investigational Drugs
Expert Testimony
Patient Selection
3 Citations (Scopus)

The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, M., Bishop, M. R., Abonour, R., Anderson, K. C., Ansell, S. M., Avigan, D., Barbarotta, L., Barrett, A. J., Besien, K., Bergsagel, P. L., Borrello, I., Brody, J., Brufsky, J., Cairo, M., Chari, A., Cohen, A., Cortes, J., Forman, S. J., Friedberg, J. W., Fuchs, E. J. & 28 others, Gore, S. D., Jagannath, S., Kahl, B. S., Kline, J., Kochenderfer, J. N., Kwak, L. W., Levy, R., Lima, M., Litzow, M. R., Mahindra, A., Miller, J., Munshi, N. C., Orlowski, R. Z., Pagel, J. M., Porter, D. L., Russell, S. J., Schwartz, K., Shipp, M. A., Siegel, D., Stone, R. M., Tallman, M. S., Timmerman, J. M., Rhee, F., Waller, E. K., Welsh, A., Werner, M., Wiernik, P. H. & Dhodapkar, M. V., Dec 20 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 90.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Multiple Myeloma
Immunotherapy
Lymphoma
Leukemia

Treatment of HIV/AIDS associated cancers with immunotherapy targeting PD-1/PD-L1 instead of chemotherapy

Kasi, P. M., Block, M. S. & Ansell, S. M., Jan 1 2016, In : Medical Hypotheses. 86, p. 129-131 3 p.

Research output: Contribution to journalArticle

Immunotherapy
Acquired Immunodeficiency Syndrome
HIV
Drug Therapy
Neoplasms
6 Citations (Scopus)
Waldenstrom Macroglobulinemia
Genomics
Mutation
Therapeutics
Plasma Exchange
8 Citations (Scopus)

Where do programmed death-1 inhibitors fit in the management of malignant lymphoma?

Ansell, S. M., Feb 1 2016, In : Journal of Oncology Practice. 12, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Lymphoma
Hodgkin Disease
T-Lymphocytes
Ligands
Death Domain Receptors
2015
29 Citations (Scopus)

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Vijai, J., Wang, Z., Berndt, S. I., Skibola, C. F., Slager, S. L., De Sanjose, S., Melbye, M., Glimelius, B., Bracci, P. M., Conde, L., Birmann, B. M., Wang, S. S., Brooks-Wilson, A. R., Lan, Q., De Bakker, P. I. W., Vermeulen, R. C. H., Portlock, C., Ansell, S. M., Link, B. K., Riby, J. & 82 others, North, K. E., Gu, J., Hjalgrim, H., Cozen, W., Becker, N., Teras, L. R., Spinelli, J. J., Turner, J., Zhang, Y., Purdue, M. P., Giles, G. G., Kelly, R. S., Zeleniuch-Jacquotte, A., Ennas, M. G., Monnereau, A., Bertrand, K. A., Albanes, D., Lightfoot, T., Yeager, M., Chung, C. C., Burdett, L., Hutchinson, A., Lawrence, C., Montalvan, R., Liang, L., Huang, J., Ma, B., Villano, D. J., Maria, A., Corines, M., Thomas, T., Novak, A. J., Dogan, A., Liebow, M., Thompson, C. A., Witzig, T. E., Habermann, T. M., Weiner, G. J., Smith, M. T., Holly, E. A., Jackson, R. D., Tinker, L. F., Ye, Y., Adami, H. O., Smedby, K. E., De Roos, A. J., Hartge, P., Morton, L. M., Severson, R. K., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., McKay, J., Staines, A., DIver, W. R., Vajdic, C. M., Armstrong, B. K., Kricker, A., Zheng, T., Holford, T. R., Severi, G., Vineis, P., Ferri, G. M., Ricco, R., Miligi, L., Clavel, J., Giovannucci, E., Kraft, P., Virtamo, J., Smith, A., Kane, E., Roman, E., Chiu, B. C. H., Fraumeni, J. F., Wu, X., Cerhan, J. R., Offit, K., Chanock, S. J., Rothman, N. & Nieters, A., Jan 8 2015, In : Nature Communications. 6, 6751.

Research output: Contribution to journalArticle

HLA-B Antigens
genome
Genome-Wide Association Study
loci
Lymphoma
12 Citations (Scopus)

Dacetuzumab plus rituximab, ifosfamide, carboplatin and etoposide as salvage therapy for patients with diffuse large B-cell lymphoma relapsing after rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone: A randomized, double-blind, placebo-controlled phase 2b trial

Fayad, L., Ansell, S. M., Advani, R., Coiffier, B., Stuart, R., Bartlett, N. L., Forero-Torres, A., Kuliczkowski, K., Belada, D., Ng, E. & Drachman, J. G., Sep 2 2015, In : Leukemia and Lymphoma. 56, 9, p. 2569-2578 10 p.

Research output: Contribution to journalArticle

Salvage Therapy
Ifosfamide
Lymphoma, Large B-Cell, Diffuse
Carboplatin
Vincristine
3 Citations (Scopus)

DNA methylation in lymphoma: An opportunity?

Ansell, S. M., Mar 19 2015, In : Blood. 125, 12, p. 1848-1849 2 p.

Research output: Contribution to journalArticle

DNA Methylation
Lymphoma
Methylation
DNA Fingerprinting
Epigenomics
131 Citations (Scopus)

Durable remissions in a pivotal phase 2 study of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma

Gopal, A. K., Chen, R., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Connors, J. M., Engert, A., Larsen, E. K., Chi, X., Sievers, E. L. & Younes, A., Feb 19 2015, In : Blood. 125, 8, p. 1236-1243 8 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Refractory materials
Transplants
Stem cells
Disease control
10 Citations (Scopus)

Early treatment of high risk chronic lymphocytic leukemia with alemtuzumab, rituximab and poly-(1-6)-beta-glucotriosyl-(1-3)- beta-glucopyranose beta-glucan is well tolerated and achieves high complete remission rates

Zent, C. S., Call, T. G., Bowen, D. A., Conte, M. J., LaPlant, B. R., Witzig, T. E., Ansell, S. M. & Weiner, G. J., Aug 3 2015, In : Leukemia and Lymphoma. 56, 8, p. 2373-2378 6 p.

Research output: Contribution to journalArticle

beta-Glucans
B-Cell Chronic Lymphocytic Leukemia
Confidence Intervals
Therapeutics
Phase II Clinical Trials
21 Citations (Scopus)

Elevated serum levels of IL-2R, IL-1RA, and CXCL9 are associated with a poor prognosis in follicular lymphoma

Mir, M. A., Maurer, M. J., Ziesmer, S. C., Slager, S. L., Habermann, T. M., Macon, W. R., Link, B. K., Syrbu, S., Witzig, T. E., Friedberg, J. W., Press, O., LeBlanc, M., Cerhan, J. R., Novak, A. J. & Ansell, S. M., Feb 5 2015, In : Blood. 125, 6, p. 992-998 7 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Chemotherapy
Interleukin-1 Receptors
Cytokines
Oncology
4 Citations (Scopus)

Emerging therapeutic options for Waldenström macroglobulinemia/lymphoplasmacytic lymphoma

Chakraborty, R., Kapoor, P., Ansell, S. M. & Gertz, M., Oct 3 2015, In : Expert Review of Anticancer Therapy. 15, 10, p. 1143-1156 14 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Lymphoma
Mutation
Therapeutics
Non-Hodgkin's Lymphoma
4 Citations (Scopus)

Expression of the chemokine receptor gene, CCR8, is associated with DUSP22 rearrangements in anaplastic large cell lymphoma

Xing, X., Flotte, T. J., Law, M. E., Blahnik, A. J., Chng, W. J., Huang, G., Knudson, R. A., Ketterling, R. P., Porcher, J. C., Ansell, S. M., Sidhu, J., Dogan, A. & Feldman, A. L., Sep 23 2015, In : Applied Immunohistochemistry and Molecular Morphology. 23, 8, p. 580-589 10 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Chemokine Receptors
Skin
Genes
In Situ Hybridization
11 Citations (Scopus)

Genome-Wide association study of event-free survival in diffuse large B-cell lymphoma treated with immunochemotherapy

Ghesquieres, H., Slager, S. L., Jardin, F., Veron, A. S., Asmann, Y., Maurer, M. J., Fest, T., Habermann, T. M., Bene, M. C., Novak, A. J., Mareschal, S., Haioun, C., Lamy, T., Ansell, S. M., Tilly, H., Witzig, T. E., Weiner, G. J., Feldman, A. L., Dogan, A., Cunningham, J. M. & 7 others, Olswold, C. L., Molina, T. J., Link, B. K., Milpied, N., Cox, D. G., Salles, G. A. & Cerhan, J. R., Nov 20 2015, In : Journal of Clinical Oncology. 33, 33, p. 3930-3937 8 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Genome-Wide Association Study
Disease-Free Survival
Single Nucleotide Polymorphism
Survival
43 Citations (Scopus)

Hodgkin lymphoma: Diagnosis and treatment

Ansell, S. M., 2015, In : Mayo Clinic Proceedings. 90, 11, p. 1574-1583 10 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Stem Cells
Therapeutics
Transplants
Drug Therapy
10 Citations (Scopus)

Ibrutinib for the treatment of Waldenström macroglobulinemia

Chakraborty, R., Kapoor, P., Ansell, S. M. & Gertz, M., Sep 3 2015, In : Expert Review of Hematology. 8, 5, p. 569-579 11 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Paraproteinemias
Poisons
B-Cell Lymphoma
Therapeutics
32 Citations (Scopus)

IL-10 induces the development of immunosuppressive CD14+ HLA-DRlow/- monocytes in B-cell non-Hodgkin lymphoma

Xiu, B., Lin, Y., Grote, D. M., Ziesmer, S. C., Gustafson, M., Maas, M. L., Zhang, Z., Dietz, A. B., Porrata, L. F., Novak, A. J., Liang, A. B., Yang, Z. Z. & Ansell, S. M., Jul 31 2015, In : Blood Cancer Journal. 5, 7, e328.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Immunosuppressive Agents
Interleukin-10
Non-Hodgkin's Lymphoma
Monocytes
7 Citations (Scopus)

Immunologic Autograft Engineering and Survival in Non-Hodgkin Lymphoma

Porrata, L. F., Burgstaler, E. A., Winters, J. L., Jacob, E. K., Gastineau, D. A., Suman, V. J., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Nevala, W. & Markovic, S. N., Sep 23 2015, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Autografts
Lymphocyte Count
Non-Hodgkin's Lymphoma
Survival
Peripheral Blood Stem Cell Transplantation
3 Citations (Scopus)
Peripheral Blood Stem Cell Transplantation
T-Cell Lymphoma
Hematopoietic Stem Cell Transplantation
Autografts
Monocytes
7 Citations (Scopus)

Infused autograft lymphocyte to monocyte ratio predicts survival in classical Hodgkin lymphoma

Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Hogan, W. & Markovic, S. N., Feb 2 2015, In : Journal of Blood Medicine. 6, p. 45-53 9 p.

Research output: Contribution to journalArticle

Autografts
Hodgkin Disease
Monocytes
Lymphocytes
Survival
197 Citations (Scopus)
Lymphoma, Large B-Cell, Diffuse
B-Lymphocytes
Phenotype
Germinal Center
Disease-Free Survival
29 Citations (Scopus)

Non-Hodgkin Lymphoma: Diagnosis and Treatment

Ansell, S. M., Aug 1 2015, In : Mayo Clinic Proceedings. 90, 8, p. 1152-1163 12 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Therapeutics
Hematopoietic System
Lymphoma
Radiotherapy
2 Citations (Scopus)

Non-Hodgkin lymphoma, body mass index, and cytokine polymorphisms: A pooled analysis from the interlymph consortium

Kane, E., Skibola, C. F., Bracci, P. M., Cerhan, J. R., Costas, L., Smedby, K. E., Holly, E. A., Maynadié, M., Novak, A. J., Lightfoot, T. J., Ansell, S. M., Smith, A. G., Liebow, M., Melbye, M., Morton, L., De Sanjosé, S., Slager, S. L., Wang, S. S., Zhang, Y., Zheng, T. & 1 others, Roman, E., Jul 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 7, p. 1061-1070 10 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Body Mass Index
Lymphoma, Large B-Cell, Diffuse
Obesity
B-Cell Chronic Lymphocytic Leukemia
1 Citation (Scopus)
Hodgkin Disease
Reed-Sternberg Cells
Drug Therapy
Tumor Microenvironment
Antibodies
1694 Citations (Scopus)

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

Ansell, S. M., Lesokhin, A. M., Borrello, I., Halwani, A., Scott, E. C., Gutierrez, M., Schuster, S. J., Millenson, M. M., Cattry, D., Freeman, G. J., Rodig, S. J., Chapuy, B., Ligon, A. H., Zhu, L., Grosso, J. F., Kim, S. Y. O., Timmerman, J. M., Shipp, M. A. & Armand, P., Jan 22 2015, In : The New England journal of medicine. 372, 4, p. 311-319 9 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Reed-Sternberg Cells
Janus Kinases
Stem Cell Transplantation
Drug-Related Side Effects and Adverse Reactions
62 Citations (Scopus)

PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Xiu, B., Novak, A. J. & Ansell, S. M., Jan 1 2015, In : Blood Cancer Journal. 5, 2, e281.

Research output: Contribution to journalArticle

Follicular Lymphoma
T-Lymphocytes
Survival
Population
Phenotype

Phase II clinical trials for Waldenstrom's macroglobulinemia

Chakraborty, R., Ansell, S. M., Kapoor, P. & Gertz, M., May 1 2015, In : Expert Opinion on Orphan Drugs. 3, 5, p. 537-547 11 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Phase II Clinical Trials
Proteasome Inhibitors
Sirolimus
Phosphatidylinositol 3-Kinases
10 Citations (Scopus)

Survival in patients with limited-stage peripheral T-cell lymphomas

Briski, R., Feldman, A. L., Bailey, N. G., Lim, M. S., Ristow, K., Habermann, T. M., Macon, W. R., Inwards, D. J., Colgan, J. P., Nowakowski, G. S., Kaminski, M. S., Witzig, T. E., Ansell, S. M. & Wilcox, R. A., Jun 1 2015, In : Leukemia and Lymphoma. 56, 6, p. 1665-1670 6 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Survival
Anaplastic Large-Cell Lymphoma
T-Cell Lymphoma
Hematopoietic Stem Cells
28 Citations (Scopus)
Waldenstrom Macroglobulinemia
Apoptosis
Proteasome Endopeptidase Complex
Neoplasms
Ubiquitinated Proteins
29 Citations (Scopus)

Targeting immune checkpoints in lymphoma

Ansell, S. M., Jul 1 2015, In : Current Opinion in Hematology. 22, 4, p. 337-342 6 p.

Research output: Contribution to journalArticle

Lymphoma
Hodgkin Disease
CD274 Antigen
Cell Death
Tumor Microenvironment
8 Citations (Scopus)

Targeting the spleen tyrosine kinase with fostamatinib as a strategy against Waldenström Macroglobulinemia

Kuiatse, I., Baladandayuthapani, V., Lin, H. Y., Thomas, S. K., Bjorklund, C. C., Weber, D. M., Wang, M., Shah, J. J., Zhang, X. D., Jones, R. J., Ansell, S. M., Yang, G., Treon, S. P. & Orlowski, R. Z., Jun 1 2015, In : Clinical Cancer Research. 21, 11, p. 2538-2545 8 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinase 3
Clonal Evolution
Cell Line