Stephen Maxted Ansell, MD, PhD &ndash; Research Output

2016

FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: A meta-analysis on 1134 patients from two prospective cohorts

Ghesquières, H., Larrabee, B. R., Haioun, C., Link, B. K., Verney, A., Slager, S. L., Ketterer, N., Ansell, S. M., Delarue, R., Maurer, M. J., Fitoussi, O., Habermann, T. M., Peyrade, F., Dogan, A., Molina, T. J., Novak, A. J., Tilly, H., Cerhan, J. R. & Salles, G., 2016, (Accepted/In press) In : Hematological Oncology.

Research output: Contribution to journal › Article

Lymphoma, Large B-Cell, Diffuse

Meta-Analysis

Disease-Free Survival

Single Nucleotide Polymorphism

Survival

136 Citations (Scopus)

Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma

Chen, R., Gopal, A. K., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Connors, J. M., Engert, A., Larsen, E. K., Huebner, D., Fong, A. & Younes, A., Sep 22 2016, In : Blood. 128, 12, p. 1562-1566 5 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Refractory materials

Durability

Survival

Stem cells

8 Citations (Scopus)

Follicular lymphoma tregs have a distinct transcription profile impacting their migration and retention in the malignant lymph node

Nedelkovska, H., Rosenberg, A. F., Hilchey, S. P., Hyrien, O., Burack, W. R., Quataert, S. A., Baker, C. M., Azadniv, M., Welle, S. L., Ansell, S. M., Kim, M. & Bernstein, S. H., May 1 2016, In : PLoS One. 11, 5, e0155347.

Research output: Contribution to journal › Article

Chemokine CXCL13

Interleukin-16

L-Selectin

Follicular Lymphoma

T-cells

26 Citations (Scopus)

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Machiela, M. J., Lan, Q., Slager, S. L., Vermeulen, R. C. H., Teras, L. R., Camp, N. J., Cerhan, J. R., Spinelli, J. J., Wang, S. S., Nieters, A., Vijai, J., Yeager, M., Wang, Z., Ghesquières, H., McKay, J., Conde, L., de Bakker, P. I. W., Cox, D. G., Burdett, L., Monnereau, A. & 100 others, Flowers, C. R., De Roos, A. J., Brooks-Wilson, A. R., Giles, G. G., Melbye, M., Gu, J., Jackson, R. D., Kane, E., Purdue, M. P., Vajdic, C. M., Albanes, D., Kelly, R. S., Zucca, M., Bertrand, K. A., Zeleniuch-Jacquotte, A., Lawrence, C., Hutchinson, A., Zhi, D., Habermann, T. M., Link, B. K., Novak, A. J., Dogan, A., Asmann, Y., Liebow, M., Thompson, C. A., Ansell, S. M., Witzig, T. E., Tilly, H., Haioun, C., Molina, T. J., Hjalgrim, H., Glimelius, B., Adami, H. O., Roos, G., Bracci, P. M., Riby, J., Smith, M. T., Holly, E. A., Cozen, W., Hartge, P., Morton, L. M., Severson, R. K., Tinker, L. F., North, K. E., Becker, N., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., Staines, A., Lightfoot, T., Crouch, S., Smith, A., Roman, E., Ryan Diver, W., Offit, K., Zelenetz, A., Klein, R. J., Villano, D. J., Zheng, T., Zhang, Y., Holford, T. R., Turner, J., Southey, M. C., Clavel, J., Virtamo, J., Weinstein, S., Riboli, E., Vineis, P., Kaaks, R., Boeing, H., Tjønneland, A., Angelucci, E., Di Lollo, S., Rais, M., De Vivo, I., Giovannucci, E., Kraft, P., Huang, J., Ma, B., Ye, Y., Chiu, B. C. H., Liang, L., Park, J. H., Chung, C. C., Weisenburger, D. D., Fraumeni, J. F., Salles, G., Glenn, M., Cannon-Albright, L., Curtin, K., Wu, X., Smedby, K. E., de Sanjose, S., Skibola, C. F., Berndt, S. I., Birmann, B. M., Chanock, S. J. & Rothman, N., Apr 15 2016, In : Human Molecular Genetics. 25, 8, p. 1663-1676 14 p., ddw027.

Research output: Contribution to journal › Article

Telomere

B-Cell Lymphoma

Non-Hodgkin's Lymphoma

B-Cell Chronic Lymphocytic Leukemia

B-Lymphocytes

1 Citation (Scopus)

Glancing at the complex biology of T-cells through the microenvironment of Hodgkin lymphoma^*

Villasboas Bisneto, J. J. C. . & Ansell, S. M., Oct 28 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-3 3 p.

Research output: Contribution to journal › Article

Cellular Microenvironment

Hodgkin Disease

T-Lymphocytes

9 Citations (Scopus)

Hodgkin lymphoma: MOPP chemotherapy to PD-1 blockade and beyond

Ansell, S. M., Jan 1 2016, In : American Journal of Hematology. 91, 1, p. 109-112 4 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Drug Therapy

Disease Management

Neoplasms

Radiotherapy

48 Citations (Scopus)

Hodgkin lymphoma: 2016 update on diagnosis, risk-stratification, and management

Ansell, S. M., Apr 1 2016, In : American Journal of Hematology. 91, 4, p. 434-442 9 p.

Research output: Contribution to journal › Article

Risk Management

Hodgkin Disease

Transplants

Drug Therapy

Radiotherapy

2 Citations (Scopus)

How to select the frontline treatment for a patient with peripheral T-cell lymphoma

Ansell, S. M., Apr 2 2016, In : Leukemia and Lymphoma. 57, 4, p. 783-788 6 p.

Research output: Contribution to journal › Article

Peripheral T-Cell Lymphoma

Lymphoproliferative Disorders

Stem Cell Transplantation

Combination Drug Therapy

Radiotherapy

2 Citations (Scopus)

Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop

Houot, R., Gaulard, P., Schreiber, R., Mellman, I., Lambotte, O., Coulie, P. G., Fest, T., Korman, A., Levy, R., Shipp, M., Tarte, K., Kohrt, H., Marabelle, A., Ansell, S. M., Watier, H., van Elsas, A., Balakumaran, A., Arce Vargas, F., Quezada, S. A., Salles, G. & 1 others, Olive, D., Jul 2 2016, In : OncoImmunology. 5, 7, e1186323.

Research output: Contribution to journal › Article

Lymphoma

Education

Antibodies

45 Citations (Scopus)

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Luchtel, R., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journal › Article

Peripheral T-Cell Lymphoma

RNA Sequence Analysis

T-cells

Gene Fusion

Fusion reactions

19 Citations (Scopus)

Large b-cell transformation in nodular lymphocyte-predominant hodgkin lymphoma: 40-year experience from a single institution

Kenderian, S., Habermann, T. M., Macon, W. R., Ristow, K. M., Ansell, S. M., Colgan, J. P., Johnston, P. B., Inwards, D. J., Markovic, S. N., Micallef, I., Thompson, C. A., Porrata, L. F., Martenson, J. A., Witzig, T. E. & Nowakowski, G. S., Apr 21 2016, In : Blood. 127, 16, p. 1960-1966 7 p.

Research output: Contribution to journal › Article

Lymphocytes

Hodgkin Disease

Lymphoma, Large B-Cell, Diffuse

Chemotherapy

Cells

15 Citations (Scopus)

Lymphoplasmacytic Lymphoma With a Non-IgM Paraprotein Shows Clinical and Pathologic Heterogeneity and May Harbor MYD88 L265P Mutations

King, R., Gonsalves, W., Ansell, S. M., Greipp, P. T., Frederick, L. A., Viswanatha, D. S., He, R., Kyle, R. A., Gertz, M., Kapoor, P., Morice, W. G. & Howard, M. T., Jun 1 2016, In : American Journal of Clinical Pathology. 145, 6, p. 843-851 9 p.

Research output: Contribution to journal › Article

Paraproteins

Waldenstrom Macroglobulinemia

Lymphoma

Mutation

Bone Marrow

357 Citations (Scopus)

Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

Younes, A., Santoro, A., Shipp, M., Zinzani, P. L., Timmerman, J. M., Ansell, S. M., Armand, P., Fanale, M., Ratanatharathorn, V., Kuruvilla, J., Cohen, J. B., Collins, G., Savage, K. J., Trneny, M., Kato, K., Farsaci, B., Parker, S. M., Rodig, S., Roemer, M. G. M., Ligon, A. H. & 1 others, Engert, A., Sep 1 2016, In : The Lancet Oncology. 17, 9, p. 1283-1294 12 p.

Research output: Contribution to journal › Article

Stem Cell Transplantation

Hodgkin Disease

Safety

Advisory Committees

cAC10-vcMMAE

10 Citations (Scopus)

Nivolumab for the treatment of classical Hodgkin lymphoma after failure of autologous stem cell transplant and brentuximab

Villasboas Bisneto, J. J. C. . & Ansell, S. M., Jan 2 2016, In : Expert Review of Anticancer Therapy. 16, 1, p. 5-12 8 p.

Research output: Contribution to journal › Article

Programmed Cell Death 1 Receptor

Hodgkin Disease

Stem Cells

Transplants

Patient Safety

361 Citations (Scopus)

Nivolumab in patients with relapsed or refractory hematologic malignancy: Preliminary results of a phase ib study

Lesokhin, A. M., Ansell, S. M., Armand, P., Scott, E. C., Halwani, A., Gutierrez, M., Millenson, M. M., Cohen, A. D., Schuster, S. J., Lebovic, D., Dhodapkar, M., Avigan, D., Chapuy, B., Ligon, A. H., Freeman, G. J., Rodig, S. J., Cattry, D., Zhu, L., Grosso, J. F., Brigid Bradley Garelik, M. & 3 others, Shipp, M. A., Borrello, I. & Timmerman, J., Aug 10 2016, In : Journal of Clinical Oncology. 34, 23, p. 2698-2704 7 p.

Research output: Contribution to journal › Article

Hematologic Neoplasms

T-Cell Lymphoma

B-Cell Lymphoma

Peripheral T-Cell Lymphoma

Mycosis Fungoides

16 Citations (Scopus)

Personalized risk prediction for event-free survival at 24 months in patients with diffuse large B-cell lymphoma

Maurer, M. J., Jais, J. P., Ghesquières, H., Witzig, T. E., Hong, F., Haioun, C., Thompson, C. A., Thieblemont, C., Micallef, I., Porrata, L. F., Ribrag, V., Nowakowski, G. S., Casasnovas, O., Bologna, S., Morschhauser, F., Morrison, V. A., Peterson, B. A., Macon, W. R., Copie-Bergman, C., Feldman, A. L. & 13 others, Syrbu, S. I., Kurtin, P. J., Gascoyne, R. D., Li, H., Allmer, C., Kahl, B. S., Ansell, S. M., Slager, S. L., Link, B. K., Salles, G., Habermann, T. M., Tilly, H. & Cerhan, J. R., Feb 1 2016, In : American Journal of Hematology. 91, 2, p. 179-184 6 p.

Research output: Contribution to journal › Article

Lymphoma, Large B-Cell, Diffuse

Disease-Free Survival

Survival

Anthracyclines

Datasets

101 Citations (Scopus)

Refinement of the Lugano Classification lymphoma response criteria in the era of immunomodulatory therapy

Cheson, B. D., Ansell, S. M., Schwartz, L., Gordon, L. I., Advani, R., Jacene, H. A., Hoos, A., Barrington, S. F. & Armand, P., Nov 24 2016, In : Blood. 128, 21, p. 2489-2496 8 p.

Research output: Contribution to journal › Article

Immunomodulation

Lymphoma

Tumors

Imaging techniques

Histology

20 Citations (Scopus)

Role of the tumor microenvironment in mature B-cell lymphoid malignancies

Fowler, N. H., Cheah, C. Y., Gascoyne, R. D., Gribben, J., Neelapu, S. S., Ghia, P., Bollard, C., Ansell, S. M., Curran, M., Wilson, W. H., O’Brien, S., Grant, C., Little, R., Zenz, T., Nastoupil, L. J. & Dunleavy, K., Apr 30 2016, In : Haematologica. 101, 5, p. 531-540 10 p.

Research output: Contribution to journal › Article

Cellular Microenvironment

Tumor Microenvironment

B-Lymphocytes

B-Cell Lymphoma

Neoplasms

42 Citations (Scopus)

Targeting the PD-1 pathway in patients with relapsed classic Hodgkin lymphoma following allogeneic stem cell transplant is safe and effective

Villasboas Bisneto, J. J. C. ., Ansell, S. M. & Witzig, T. E., Mar 15 2016, In : Oncotarget. 7, 11, p. 13260-13264 5 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Stem Cells

Transplants

Stem Cell Transplantation

Graft vs Host Disease

29 Citations (Scopus)

The landscape of new drugs in lymphoma

Younes, A., Ansell, S. M., Fowler, N., Wilson, W., de Vos, S., Seymour, J., Advani, R., Forero, A., Morschhauser, F., Kersten, M. J., Tobinai, K., Zinzani, P. L., Zucca, E., Abramson, J. & Vose, J., Dec 29 2016, (Accepted/In press) In : Nature Reviews Clinical Oncology.

Research output: Contribution to journal › Article

Lymphoma

Pharmaceutical Preparations

Investigational Drugs

Expert Testimony

Patient Selection

3 Citations (Scopus)

The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, M., Bishop, M. R., Abonour, R., Anderson, K. C., Ansell, S. M., Avigan, D., Barbarotta, L., Barrett, A. J., Besien, K., Bergsagel, P. L., Borrello, I., Brody, J., Brufsky, J., Cairo, M., Chari, A., Cohen, A., Cortes, J., Forman, S. J., Friedberg, J. W., Fuchs, E. J. & 28 others, Gore, S. D., Jagannath, S., Kahl, B. S., Kline, J., Kochenderfer, J. N., Kwak, L. W., Levy, R., Lima, M., Litzow, M. R., Mahindra, A., Miller, J., Munshi, N. C., Orlowski, R. Z., Pagel, J. M., Porter, D. L., Russell, S. J., Schwartz, K., Shipp, M. A., Siegel, D., Stone, R. M., Tallman, M. S., Timmerman, J. M., Rhee, F., Waller, E. K., Welsh, A., Werner, M., Wiernik, P. H. & Dhodapkar, M. V., Dec 20 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 90.

Research output: Contribution to journal › Article

Hematologic Neoplasms

Multiple Myeloma

Immunotherapy

Lymphoma

Leukemia

Treatment of HIV/AIDS associated cancers with immunotherapy targeting PD-1/PD-L1 instead of chemotherapy

Kasi, P. M., Block, M. S. & Ansell, S. M., Jan 1 2016, In : Medical Hypotheses. 86, p. 129-131 3 p.

Research output: Contribution to journal › Article

Immunotherapy

Acquired Immunodeficiency Syndrome

HIV

Drug Therapy

Neoplasms

6 Citations (Scopus)

Waldenstrom Macroglobulinemia: Familial Predisposition and the Role of Genomics in Prognosis and Treatment Selection

Kapoor, P., Paludo, J. & Ansell, S. M., Mar 1 2016, In : Current Treatment Options in Oncology. 17, 3, 16.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Genomics

Mutation

Therapeutics

Plasma Exchange

8 Citations (Scopus)

Where do programmed death-1 inhibitors fit in the management of malignant lymphoma?

Ansell, S. M., Feb 1 2016, In : Journal of Oncology Practice. 12, 2, p. 101-106 6 p.

Research output: Contribution to journal › Article

Lymphoma

Hodgkin Disease

T-Lymphocytes

Ligands

Death Domain Receptors

2015

29 Citations (Scopus)

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Vijai, J., Wang, Z., Berndt, S. I., Skibola, C. F., Slager, S. L., De Sanjose, S., Melbye, M., Glimelius, B., Bracci, P. M., Conde, L., Birmann, B. M., Wang, S. S., Brooks-Wilson, A. R., Lan, Q., De Bakker, P. I. W., Vermeulen, R. C. H., Portlock, C., Ansell, S. M., Link, B. K., Riby, J. & 82 others, North, K. E., Gu, J., Hjalgrim, H., Cozen, W., Becker, N., Teras, L. R., Spinelli, J. J., Turner, J., Zhang, Y., Purdue, M. P., Giles, G. G., Kelly, R. S., Zeleniuch-Jacquotte, A., Ennas, M. G., Monnereau, A., Bertrand, K. A., Albanes, D., Lightfoot, T., Yeager, M., Chung, C. C., Burdett, L., Hutchinson, A., Lawrence, C., Montalvan, R., Liang, L., Huang, J., Ma, B., Villano, D. J., Maria, A., Corines, M., Thomas, T., Novak, A. J., Dogan, A., Liebow, M., Thompson, C. A., Witzig, T. E., Habermann, T. M., Weiner, G. J., Smith, M. T., Holly, E. A., Jackson, R. D., Tinker, L. F., Ye, Y., Adami, H. O., Smedby, K. E., De Roos, A. J., Hartge, P., Morton, L. M., Severson, R. K., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., McKay, J., Staines, A., DIver, W. R., Vajdic, C. M., Armstrong, B. K., Kricker, A., Zheng, T., Holford, T. R., Severi, G., Vineis, P., Ferri, G. M., Ricco, R., Miligi, L., Clavel, J., Giovannucci, E., Kraft, P., Virtamo, J., Smith, A., Kane, E., Roman, E., Chiu, B. C. H., Fraumeni, J. F., Wu, X., Cerhan, J. R., Offit, K., Chanock, S. J., Rothman, N. & Nieters, A., Jan 8 2015, In : Nature Communications. 6, 6751.

Research output: Contribution to journal › Article

HLA-B Antigens

genome

Genome-Wide Association Study

loci

Lymphoma

12 Citations (Scopus)

Dacetuzumab plus rituximab, ifosfamide, carboplatin and etoposide as salvage therapy for patients with diffuse large B-cell lymphoma relapsing after rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone: A randomized, double-blind, placebo-controlled phase 2b trial

Fayad, L., Ansell, S. M., Advani, R., Coiffier, B., Stuart, R., Bartlett, N. L., Forero-Torres, A., Kuliczkowski, K., Belada, D., Ng, E. & Drachman, J. G., Sep 2 2015, In : Leukemia and Lymphoma. 56, 9, p. 2569-2578 10 p.

Research output: Contribution to journal › Article

Salvage Therapy

Ifosfamide

Lymphoma, Large B-Cell, Diffuse

Carboplatin

Vincristine

3 Citations (Scopus)

DNA methylation in lymphoma: An opportunity?

Ansell, S. M., Mar 19 2015, In : Blood. 125, 12, p. 1848-1849 2 p.

Research output: Contribution to journal › Article

DNA Methylation

Lymphoma

Methylation

DNA Fingerprinting

Epigenomics

131 Citations (Scopus)

Durable remissions in a pivotal phase 2 study of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma

Gopal, A. K., Chen, R., Smith, S. E., Ansell, S. M., Rosenblatt, J. D., Savage, K. J., Connors, J. M., Engert, A., Larsen, E. K., Chi, X., Sievers, E. L. & Younes, A., Feb 19 2015, In : Blood. 125, 8, p. 1236-1243 8 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Refractory materials

Transplants

Stem cells

Disease control

10 Citations (Scopus)

Early treatment of high risk chronic lymphocytic leukemia with alemtuzumab, rituximab and poly-(1-6)-beta-glucotriosyl-(1-3)- beta-glucopyranose beta-glucan is well tolerated and achieves high complete remission rates

Zent, C. S., Call, T. G., Bowen, D. A., Conte, M. J., LaPlant, B. R., Witzig, T. E., Ansell, S. M. & Weiner, G. J., Aug 3 2015, In : Leukemia and Lymphoma. 56, 8, p. 2373-2378 6 p.

Research output: Contribution to journal › Article

beta-Glucans

B-Cell Chronic Lymphocytic Leukemia

Confidence Intervals

Therapeutics

Phase II Clinical Trials

21 Citations (Scopus)

Elevated serum levels of IL-2R, IL-1RA, and CXCL9 are associated with a poor prognosis in follicular lymphoma

Mir, M. A., Maurer, M. J., Ziesmer, S. C., Slager, S. L., Habermann, T. M., Macon, W. R., Link, B. K., Syrbu, S., Witzig, T. E., Friedberg, J. W., Press, O., LeBlanc, M., Cerhan, J. R., Novak, A. J. & Ansell, S. M., Feb 5 2015, In : Blood. 125, 6, p. 992-998 7 p.

Research output: Contribution to journal › Article

Follicular Lymphoma

Chemotherapy

Interleukin-1 Receptors

Cytokines

Oncology

4 Citations (Scopus)

Emerging therapeutic options for Waldenström macroglobulinemia/lymphoplasmacytic lymphoma

Chakraborty, R., Kapoor, P., Ansell, S. M. & Gertz, M., Oct 3 2015, In : Expert Review of Anticancer Therapy. 15, 10, p. 1143-1156 14 p.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Lymphoma

Mutation

Therapeutics

Non-Hodgkin's Lymphoma

4 Citations (Scopus)

Expression of the chemokine receptor gene, CCR8, is associated with DUSP22 rearrangements in anaplastic large cell lymphoma

Xing, X., Flotte, T. J., Law, M. E., Blahnik, A. J., Chng, W. J., Huang, G., Knudson, R. A., Ketterling, R. P., Porcher, J. C., Ansell, S. M., Sidhu, J., Dogan, A. & Feldman, A. L., Sep 23 2015, In : Applied Immunohistochemistry and Molecular Morphology. 23, 8, p. 580-589 10 p.

Research output: Contribution to journal › Article

Anaplastic Large-Cell Lymphoma

Chemokine Receptors

Skin

Genes

In Situ Hybridization

11 Citations (Scopus)

Genome-Wide association study of event-free survival in diffuse large B-cell lymphoma treated with immunochemotherapy

Ghesquieres, H., Slager, S. L., Jardin, F., Veron, A. S., Asmann, Y., Maurer, M. J., Fest, T., Habermann, T. M., Bene, M. C., Novak, A. J., Mareschal, S., Haioun, C., Lamy, T., Ansell, S. M., Tilly, H., Witzig, T. E., Weiner, G. J., Feldman, A. L., Dogan, A., Cunningham, J. M. & 7 others, Olswold, C. L., Molina, T. J., Link, B. K., Milpied, N., Cox, D. G., Salles, G. A. & Cerhan, J. R., Nov 20 2015, In : Journal of Clinical Oncology. 33, 33, p. 3930-3937 8 p.

Research output: Contribution to journal › Article

Lymphoma, Large B-Cell, Diffuse

Genome-Wide Association Study

Disease-Free Survival

Single Nucleotide Polymorphism

Survival

43 Citations (Scopus)

Hodgkin lymphoma: Diagnosis and treatment

Ansell, S. M., 2015, In : Mayo Clinic Proceedings. 90, 11, p. 1574-1583 10 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Stem Cells

Therapeutics

Transplants

Drug Therapy

10 Citations (Scopus)

Ibrutinib for the treatment of Waldenström macroglobulinemia

Chakraborty, R., Kapoor, P., Ansell, S. M. & Gertz, M., Sep 3 2015, In : Expert Review of Hematology. 8, 5, p. 569-579 11 p.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Paraproteinemias

Poisons

B-Cell Lymphoma

Therapeutics

32 Citations (Scopus)

IL-10 induces the development of immunosuppressive CD14⁺ HLA-DR^low/- monocytes in B-cell non-Hodgkin lymphoma

Xiu, B., Lin, Y., Grote, D. M., Ziesmer, S. C., Gustafson, M., Maas, M. L., Zhang, Z., Dietz, A. B., Porrata, L. F., Novak, A. J., Liang, A. B., Yang, Z. Z. & Ansell, S. M., Jul 31 2015, In : Blood Cancer Journal. 5, 7, e328.

Research output: Contribution to journal › Article

B-Cell Lymphoma

Immunosuppressive Agents

Interleukin-10

Non-Hodgkin's Lymphoma

Monocytes

7 Citations (Scopus)

Immunologic Autograft Engineering and Survival in Non-Hodgkin Lymphoma

Porrata, L. F., Burgstaler, E. A., Winters, J. L., Jacob, E. K., Gastineau, D. A., Suman, V. J., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Nevala, W. & Markovic, S. N., Sep 23 2015, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journal › Article

Autografts

Lymphocyte Count

Non-Hodgkin's Lymphoma

Survival

Peripheral Blood Stem Cell Transplantation

3 Citations (Scopus)

Infused autograft lymphocyte-to-monocyte ratio and survival in T-cell lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation

Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Hogan, W. & Markovic, S. N., Jul 3 2015, In : Journal of Hematology and Oncology. 8, 1, 5.

Research output: Contribution to journal › Article

Peripheral Blood Stem Cell Transplantation

T-Cell Lymphoma

Hematopoietic Stem Cell Transplantation

Autografts

Monocytes

7 Citations (Scopus)

Infused autograft lymphocyte to monocyte ratio predicts survival in classical Hodgkin lymphoma

Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Hogan, W. & Markovic, S. N., Feb 2 2015, In : Journal of Blood Medicine. 6, p. 45-53 9 p.

Research output: Contribution to journal › Article

Autografts

Hodgkin Disease

Monocytes

Lymphocytes

Survival

197 Citations (Scopus)

Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non-germinal center B-cell phenotype in newly diagnosed diffuse large B-cell lymphoma: A phase II study

Nowakowski, G. S., LaPlant, B., Macon, W. R., Reeder, C. B., Foran, J. M., Nelson, G. D., Thompson, C. A., Rivera, C. E., Inwards, D. J., Micallef, I., Johnston, P. B., Porrata, L. F., Ansell, S. M., Gascoyne, R. D., Habermann, T. M. & Witzig, T. E., Jan 20 2015, In : Journal of Clinical Oncology. 33, 3, p. 251-257 7 p.

Research output: Contribution to journal › Article

Lymphoma, Large B-Cell, Diffuse

B-Lymphocytes

Phenotype

Germinal Center

Disease-Free Survival

29 Citations (Scopus)

Non-Hodgkin Lymphoma: Diagnosis and Treatment

Ansell, S. M., Aug 1 2015, In : Mayo Clinic Proceedings. 90, 8, p. 1152-1163 12 p.

Research output: Contribution to journal › Article

Non-Hodgkin's Lymphoma

Therapeutics

Hematopoietic System

Lymphoma

Radiotherapy

2 Citations (Scopus)

Non-Hodgkin lymphoma, body mass index, and cytokine polymorphisms: A pooled analysis from the interlymph consortium

Kane, E., Skibola, C. F., Bracci, P. M., Cerhan, J. R., Costas, L., Smedby, K. E., Holly, E. A., Maynadié, M., Novak, A. J., Lightfoot, T. J., Ansell, S. M., Smith, A. G., Liebow, M., Melbye, M., Morton, L., De Sanjosé, S., Slager, S. L., Wang, S. S., Zhang, Y., Zheng, T. & 1 others, Roman, E., Jul 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 7, p. 1061-1070 10 p.

Research output: Contribution to journal › Article

Non-Hodgkin's Lymphoma

Body Mass Index

Lymphoma, Large B-Cell, Diffuse

Obesity

B-Cell Chronic Lymphocytic Leukemia

1 Citation (Scopus)

Novel agents in the therapy of Hodgkin lymphoma

Ansell, S. M., 2015, In : American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting. p. e479-e482

Research output: Contribution to journal › Article

Hodgkin Disease

Reed-Sternberg Cells

Drug Therapy

Tumor Microenvironment

Antibodies

1694 Citations (Scopus)

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

Ansell, S. M., Lesokhin, A. M., Borrello, I., Halwani, A., Scott, E. C., Gutierrez, M., Schuster, S. J., Millenson, M. M., Cattry, D., Freeman, G. J., Rodig, S. J., Chapuy, B., Ligon, A. H., Zhu, L., Grosso, J. F., Kim, S. Y. O., Timmerman, J. M., Shipp, M. A. & Armand, P., Jan 22 2015, In : The New England journal of medicine. 372, 4, p. 311-319 9 p.

Research output: Contribution to journal › Article

Hodgkin Disease

Reed-Sternberg Cells

Janus Kinases

Stem Cell Transplantation

Drug-Related Side Effects and Adverse Reactions

62 Citations (Scopus)

PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Xiu, B., Novak, A. J. & Ansell, S. M., Jan 1 2015, In : Blood Cancer Journal. 5, 2, e281.

Research output: Contribution to journal › Article

Follicular Lymphoma

T-Lymphocytes

Survival

Population

Phenotype

Phase II clinical trials for Waldenstrom's macroglobulinemia

Chakraborty, R., Ansell, S. M., Kapoor, P. & Gertz, M., May 1 2015, In : Expert Opinion on Orphan Drugs. 3, 5, p. 537-547 11 p.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Phase II Clinical Trials

Proteasome Inhibitors

Sirolimus

Phosphatidylinositol 3-Kinases

10 Citations (Scopus)

Survival in patients with limited-stage peripheral T-cell lymphomas

Briski, R., Feldman, A. L., Bailey, N. G., Lim, M. S., Ristow, K., Habermann, T. M., Macon, W. R., Inwards, D. J., Colgan, J. P., Nowakowski, G. S., Kaminski, M. S., Witzig, T. E., Ansell, S. M. & Wilcox, R. A., Jun 1 2015, In : Leukemia and Lymphoma. 56, 6, p. 1665-1670 6 p.

Research output: Contribution to journal › Article

Peripheral T-Cell Lymphoma

Survival

Anaplastic Large-Cell Lymphoma

T-Cell Lymphoma

Hematopoietic Stem Cells

28 Citations (Scopus)

Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells

Chitta, K., Paulus, A., Akhtar, S., Blake, M. K. K., Caulfield, T., Novak, A. J., Ansell, S. M., Advani, P., Ailawadhi, S., Sher, T., Linder, S. & Chanan Khan, A. A., May 1 2015, In : British Journal of Haematology. 169, 3, p. 377-390 14 p.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Apoptosis

Proteasome Endopeptidase Complex

Neoplasms

Ubiquitinated Proteins

29 Citations (Scopus)

Targeting immune checkpoints in lymphoma

Ansell, S. M., Jul 1 2015, In : Current Opinion in Hematology. 22, 4, p. 337-342 6 p.

Research output: Contribution to journal › Article

Lymphoma

Hodgkin Disease

CD274 Antigen

Cell Death

Tumor Microenvironment

8 Citations (Scopus)

Targeting the spleen tyrosine kinase with fostamatinib as a strategy against Waldenström Macroglobulinemia

Kuiatse, I., Baladandayuthapani, V., Lin, H. Y., Thomas, S. K., Bjorklund, C. C., Weber, D. M., Wang, M., Shah, J. J., Zhang, X. D., Jones, R. J., Ansell, S. M., Yang, G., Treon, S. P. & Orlowski, R. Z., Jun 1 2015, In : Clinical Cancer Research. 21, 11, p. 2538-2545 8 p.

Research output: Contribution to journal › Article

Waldenstrom Macroglobulinemia

Mitogen-Activated Protein Kinase Kinases

Mitogen-Activated Protein Kinase 3

Clonal Evolution

Cell Line