Stephen Maxted Ansell, MD, PhD

  • 22094 Citations
  • 80 Scopus h-Index
1976 …2020

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33 Scopus citations

Targeting CD38 with daratumumab is lethal to Waldenström macroglobulinaemia cells

Paulus, A., Manna, A., Akhtar, S., Paulus, S. M., Sharma, M., Coignet, M. V., Jiang, L., Roy, V., Witzig, T. E., Ansell, S. M., Allan, J., Furman, R., Aulakh, S., Manochakian, R., Ailawadhi, S., Chanan Khan, A. A. & Sher, T., Jan 1 2018, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

1 Scopus citations

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Wu, X., Stenson, M., Abeykoon, J., Nowakowski, K., Zhang, L., Lawson, J., Wellik, L., Li, Y., Krull, J., Wenzl, K., Novak, A. J., Ansell, S. M., Bishop, G. A., Billadeau, D. D., Peng, K. W., Giles, F., Schmitt, D. M. & Witzig, T. E., Jul 25 2019, In : Blood. 134, 4, p. 363-373 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Targeting immune checkpoints in lymphoma

Ansell, S. M., Jul 1 2015, In : Current Opinion in Hematology. 22, 4, p. 337-342 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Targeting myddosome signaling in Waldenstrom's macroglobulinemia with the interleukin-1 receptor-associated kinase 1/4 inhibitor R191

Ni, H., Shirazi, F., Baladandayuthapani, V., Lin, H., Kuiatse, I., Wang, H., Jones, R. J., Berkova, Z., Hitoshi, Y., Ansell, S. M., Treon, S. P., Thomas, S. K., Lee, H. C., Wang, Z., Eric Davis, R. & Orlowski, R. Z., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6408-6420 13 p.

Research output: Contribution to journalArticle

2 Scopus citations
42 Scopus citations

Targeting the spleen tyrosine kinase with fostamatinib as a strategy against Waldenström Macroglobulinemia

Kuiatse, I., Baladandayuthapani, V., Lin, H. Y., Thomas, S. K., Bjorklund, C. C., Weber, D. M., Wang, M., Shah, J. J., Zhang, X. D., Jones, R. J., Ansell, S. M., Yang, G., Treon, S. P. & Orlowski, R. Z., Jun 1 2015, In : Clinical Cancer Research. 21, 11, p. 2538-2545 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

T-cell-mediated antitumor immunity in B-cell non-Hodgkin lymphoma: Activation, suppression and exhaustion

Yang, Z. Z., Liang, A. B. & Ansell, S. M., Sep 2 2015, In : Leukemia and Lymphoma. 56, 9, p. 2498-2504 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

Terminal plasmocytoid differentiation of malignant B cells induced by autotumor-reactive CD4+ T cells in one case of splenic marginal zone B-cell lymphoma [2]

Ansell, S. M., Witzig, T. E., Kurtin, P. J., Sloan, J. A., Jelinek, D. F., Howell, K. G., Markovic, S. N., Habermann, T. M., Klee, G. G., Atherton, P. J. & Erlichman, C., Jan 1 2002, In : Blood. 99, 1, p. 388-390 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

TGF-Β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma

Yang, Z. Z., Grote, D. M., Xiu, B., Ziesmer, S. C., Price-Troska, T. L., Hodge, L. S., Yates, D. M., Novak, A. J. & Ansell, S. M., 2014, In : Leukemia. 28, 9, p. 1872-1884 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Thalidomide treatment in myelofibrosis with myeloid metaplasia

Elliott, M. A., Mesa, R. A., Li, C. Y., Hook, C. C., Ansell, S. M., Levitt, R. M., Geyer, S. M. & Tefferi, A., 2002, In : British Journal of Haematology. 117, 2, p. 288-296 9 p.

Research output: Contribution to journalArticle

107 Scopus citations

The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Sep 2011, In : Leukemia. 25, 9, p. 1502-1509 8 p.

Research output: Contribution to journalArticle

115 Scopus citations

The absolute monocyte count is associated with overall survival in patients newly diagnosed with follicular lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Apr 2012, In : Leukemia and Lymphoma. 53, 4, p. 575-580 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

The B7 Homologues and their Receptors in Hematologic Malignancies

Wilcox, R. A., Ansell, S. M., Lim, M. S., Zou, W. & Chen, L., Jun 2012, In : European Journal of Haematology. 88, 6, p. 465-475 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

The Bone Marrow Microenvironment in Waldenström Macroglobulinemia

Jalali, S. & Ansell, S. M., Jan 1 2018, (Accepted/In press) In : Hematology/Oncology Clinics of North America.

Research output: Contribution to journalArticle

The definition of IgM multiple myeloma

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Moreno Aspitia, A., Ansell, S. M., Kyle, R. & Mikhael, J. R., Aug 2011, In : American Journal of Hematology. 86, 8, p. 718-719 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

The effect of absolute lymphocyte count recovery kinetics on survival after autologous stem cell transplantation for non-Hodgkin's lymphoma

Yoong, Y., Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I., Litzow, M. R., Gertz, M., Lacy, M., Dispenzieri, A., Gastineau, D. A., Tefferi, A., Elliott, M., Snow, D. S., Hogan, W. & Markovic, S. N., Sep 2005, In : Leukemia and Lymphoma. 46, 9, p. 1287-1294 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The era of immuno-oncology: are we there yet?

Villasboas, J. C. & Ansell, S. M., Mar 1 2015, In : Oncology (Williston Park, N.Y.). 29, 3, p. 204-205 2 p.

Research output: Contribution to journalArticle

The era of immuno-oncology: Are we there yet?

Villasboas Bisneto, J. J. C. . & Ansell, S. M., Mar 15 2015, In : ONCOLOGY (United States). 29, 3

Research output: Contribution to journalArticle

The highs and lows of immune-checkpoint blockade in lymphoma

Ansell, S. M., May 1 2019, In : Cancer Immunology Research. 7, 5, p. 696-700 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

The international prognostic index predicts outcome after histological transformation of low-grade non-Hodgkin lymphoma

Micallef, I., McPhail, E., Ansell, S. M., Colgan, J. P., Inwards, D. J., Johnston, P. B., Lewis, J. T., Markovic, S. N., Porrata, L. F., White, W. L., Witzig, T. E., Ristow, K. & Habermann, T. M., Sep 2006, In : Leukemia and Lymphoma. 47, 9, p. 1794-1799 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

The landscape of new drugs in lymphoma

Younes, A., Ansell, S. M., Fowler, N., Wilson, W., de Vos, S., Seymour, J., Advani, R., Forero, A., Morschhauser, F., Kersten, M. J., Tobinai, K., Zinzani, P. L., Zucca, E., Abramson, J. & Vose, J., Dec 29 2016, (Accepted/In press) In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalArticle

32 Scopus citations

T helper cell activation in B-cell lymphomas [1] (multiple letters)

Bosshart, H., Ansell, S. M., Jelinek, D. F., Wettstein, P. J. & Witzig, T. E., Jun 15 2002, In : Journal of Clinical Oncology. 20, 12, p. 2904-2905 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

The mTORC1 inhibitor everolimus has antitumor activity in vitro and produces tumor responses in patients with relapsed T-cell lymphoma

Witzig, T. E., Reeder, C., Han, J. J., LaPlant, B., Stenson, M., Tun, H. W., Macon, W., Ansell, S. M., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Porrata, L. F., Colgan, J. P., Markovic, S. N., Nowakowski, G. S. & Gupta, M., Jul 16 2015, In : Blood. 126, 3, p. 328-335 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

Luchtel, R., Kip, N. S., Xing, X., Zeng, Y., Yang, Z. Z., Lee, J. H., Almada, L. L., Elsawa, S. F., Knudson, R. A., Law, M. E., Ketterling, R. P., Cunningham, J. M., Wu, Y., Maurer, M. J., O'Byrne, M. M., Cerhan, J. R., Slager, S. L., Link, B. K., Porcher, J. C., Grote, D. M. & 5 others, Jelinek, D. F., Dogan, A., Ansell, S. M., Fernandez-Zapico, M. E. & Feldman, A. L., May 14 2015, In : Blood. 125, 20, p. 3118-3127 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Therapeutic Options in Patients with Lymphoma and Severe Liver Dysfunction

Ghobrial, I. M., Wolf, R. C., Pereira, D. L., Fonseca, R., White, W. L., Colgan, J. P., Habermann, T. M., Inwards, D. J., Markovic, S. N., Ansell, S. M., Micallef, I., Porrata, L. F. & Witzig, T. E., 2004, In : Mayo Clinic Proceedings. 79, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
4 Scopus citations

The role of front-line anthracycline-containing chemotherapy regimens in peripheral T-cell lymphomas

Briski, R., Feldman, A. L., Bailey, N. G., Lim, M. S., Ristow, K., Habermann, T. M., Macon, W. R., Inwards, D. J., Colgan, J. P., Nowakowski, G. S., Kaminski, M. S., Witzig, T. E., Ansell, S. M. & Wilcox, R. A., 2014, In : Blood Cancer Journal. 4, 5, e214.

Research output: Contribution to journalArticle

34 Scopus citations

The role of Treg cells in the cancer immunological response

Yang, Z. Z. & Ansell, S. M., 2009, In : American Journal of Immunology. 5, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, M., Bishop, M. R., Abonour, R., Anderson, K. C., Ansell, S. M., Avigan, D., Barbarotta, L., Barrett, A. J., Besien, K., Bergsagel, P. L., Borrello, I., Brody, J., Brufsky, J., Cairo, M., Chari, A., Cohen, A., Cortes, J., Forman, S. J., Friedberg, J. W., Fuchs, E. J. & 28 others, Gore, S. D., Jagannath, S., Kahl, B. S., Kline, J., Kochenderfer, J. N., Kwak, L. W., Levy, R., Lima, M., Litzow, M. R., Mahindra, A., Miller, J., Munshi, N. C., Orlowski, R. Z., Pagel, J. M., Porter, D. L., Russell, S. J., Schwartz, K., Shipp, M. A., Siegel, D., Stone, R. M., Tallman, M. S., Timmerman, J. M., Rhee, F., Waller, E. K., Welsh, A., Werner, M., Wiernik, P. H. & Dhodapkar, M. V., Dec 20 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 90.

Research output: Contribution to journalArticle

6 Scopus citations

The tumor microenvironment in follicular lymphoma

Yang, Z. Z. & Ansell, S. M., Dec 2012, In : Clinical Advances in Hematology and Oncology. 10, 12, p. 810-818 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

The use of cell lines for the study of Waldenström's macroglobulinemia

Gertz, M. & Ansell, S. M., Nov 2008, In : Leukemia Research. 32, 11, p. 1648-1649 2 p.

Research output: Contribution to journalArticle

The value of [18f]fluorodeoxyglucose positron emission tomography/computed tomography in extranodal natural killer/T-cell lymphoma

Karantanis, D., Subramaniam, R. M., Peller, P. J., Lowe, V., Durski, J. M., Collins, D. A., Georgiou, E., Ansell, S. M. & Wiseman, G. A., Apr 2008, In : Clinical Lymphoma and Myeloma. 8, 2, p. 94-99 6 p.

Research output: Contribution to journalArticle

38 Scopus citations
18 Scopus citations

Timing of autologous stem cell transplantation from last chemotherapy affects lymphocyte collection and survival in non-Hodgkin lymphoma

Holtan, S. G., Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I., Johnston, P. B., Litzow, M. R., Gastineau, D. A. & Markovic, S. N., Jun 2006, In : British Journal of Haematology. 133, 6, p. 628-633 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Topotecan in patients with advanced neuroendocrine tumors: A phase II study with significant hematologic toxicity

Ansell, S. M., Mahoney, M. R., Green, E. M. & Rubin, J., Jun 2004, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 27, 3, p. 232-235 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Treatment of HIV/AIDS associated cancers with immunotherapy targeting PD-1/PD-L1 instead of chemotherapy

Kasi, P. M., Block, M. S. & Ansell, S. M., Jan 1 2016, In : Medical Hypotheses. 86, p. 129-131 3 p.

Research output: Contribution to journalArticle

Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis

Wang, Y., Zhou, S., Yang, F., Qi, X., Wang, X., Guan, X., Shen, C., Duma, N., Vera Aguilera, J., Chintakuntlawar, A., Price, K. A., Molina, J. R., Pagliaro, L. C., Halfdanarson, T. R., Grothey, A. F., Markovic, S. N., Nowakowski, G. S., Ansell, S. M. & Wang, M. L., Jan 1 2019, In : JAMA Oncology.

Research output: Contribution to journalArticle

43 Scopus citations

Trisomy 5 in Ph+ chronic myeloid leukemia in association with megakaryocytosis

Ansell, S. M., Rapoport, B. L., Coccia-Portugal, M. A., Stevens, K., Bester, C. J. & Falkson, G., 1991, In : Cancer Genetics and Cytogenetics. 51, 2, p. 273-275 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia

McMaster, M. L., Berndt, S. I., Zhang, J., Slager, S. L., Li, S. A., Vajdic, C. M., Smedby, K. E., Yan, H. D., Birmann, B. M., Brown, E. E., Smith, A., Kleinstern, G., Fansler, M. M., Mayr, C., Zhu, B., Chung, C. C., Park, J. H., Burdette, L., Hicks, B. D., Hutchinson, A. & 61 others, Teras, L. R., Adami, H. O., Bracci, P. M., McKay, J., Monnereau, A., Link, B. K., Vermeulen, R. C. H., Ansell, S. M., Maria, A., Diver, W. R., Melbye, M., Ojesina, A. I., Kraft, P., Boffetta, P., Clavel, J., Giovannucci, E., Besson, C. M., Canzian, F., Travis, R. C., Vineis, P., Weiderpass, E., Montalvan, R., Wang, Z., Yeager, M., Becker, N., Benavente, Y., Brennan, P., Foretova, L., Maynadie, M., Nieters, A., de Sanjose, S., Staines, A., Conde, L., Riby, J., Glimelius, B., Hjalgrim, H., Pradhan, N., Feldman, A. L., Novak, A. J., Lawrence, C., Bassig, B. A., Lan, Q., Zheng, T., North, K. E., Tinker, L. F., Cozen, W., Severson, R. K., Hofmann, J. N., Zhang, Y., Jackson, R. D., Morton, L. M., Purdue, M. P., Chatterjee, N., Offit, K., Cerhan, J. R., Chanock, S. J., Rothman, N., Vijai, J., Goldin, L. R., Skibola, C. F. & Caporaso, N. E., Dec 1 2018, In : Nature Communications. 9, 1, 4182.

Research output: Contribution to journalArticle

2 Scopus citations

Two targets for the price of one

Ansell, S. M., Oct 10 2013, In : Blood. 122, 15, p. 2529-2531 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Two types of amyloidosis presenting in a single patient: a case series

Sidiqi, M. H., McPhail, E., Theis, J. D., Dasari, S., Vrana, J. A., Drosou, M. E., Leung, N., Hayman, S., Rajkumar, S. V., Warsame, R., Ansell, S. M., Gertz, M., Grogan, M. & Dispenzieri, A., Mar 1 2019, In : Blood cancer journal. 9, 3, 30.

Research output: Contribution to journalArticle

3 Scopus citations

Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor

Hussain, S., Feldman, A. L., Das, C., Ziesmer, S. C., Ansell, S. M. & Galardy, P. J., Mar 2013, In : Molecular and Cellular Biology. 33, 6, p. 1188-1197 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Utility of routine post-therapy surveillance imaging in diffuse large B-cell lymphoma

Thompson, C. A., Ghesquieres, H., Maurer, M. J., Cerhan, J. R., Biron, P., Ansell, S. M., Chassagne-Clément, C., Inwards, D. J., Gargi, T., Johnston, P. B., Nicolas-Virelizier, E., Macon, W. R., Peix, M., Micallef, I., Sebban, C., Nowakowski, G. S., Porrata, L. F., Weiner, G. J., Witzig, T. E., Habermann, T. M. & 1 others, Link, B. K., Nov 1 2014, In : Journal of Clinical Oncology. 32, 31, p. 3506-3512 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma

Drake, M. M., Maurer, M. J., Link, B. K., Habermann, T. M., Ansell, S. M., Micallef, I., Kelly, J. L., Macon, W. R., Nowakowski, G. S., Inwards, D. J., Johnston, P. B., Singh, R. J., Allmer, C., Slager, S. L., Weiner, G. J., Witzig, T. E. & Cerhan, J. R., Sep 20 2010, In : Journal of Clinical Oncology. 28, 27, p. 4191-4198 8 p.

Research output: Contribution to journalArticle

158 Scopus citations

Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma

Tracy, S. I., Maurer, M. J., Witzig, T. E., Drake, M. M., Ansell, S. M., Nowakowski, G. S., Thompson, C. A., Inwards, D. J., Johnston, P. B., Micallef, I., Allmer, C., MacOn, W. R., Weiner, G. J., Slager, S. L., Habermann, T. M., Link, B. K. & Cerhan, J. R., Aug 25 2017, In : Blood Cancer Journal. 7, 8, e595.

Research output: Contribution to journalArticle

6 Scopus citations

WaldenstroM Macroglobulinaemia: The Key Questions

D'Souza, A., Ansell, S. M., Reeder, C. & Gertz, M., Aug 2013, In : British Journal of Haematology. 162, 3, p. 295-303 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations