• 11733 Citations
  • 54 Scopus h-Index
1991 …2020

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2019

Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists

Greenberg-Worisek, A. J., Campbell, K. A., Klee, E. W., Staff, N. P., Schimmenti, L. A., Weavers, K. M., Ekker, S. C. & Windebank, A. J., Feb 1 2019, In : Academic medicine : journal of the Association of American Medical Colleges. 94, 2, p. 213-216 4 p.

Research output: Contribution to journalArticle

The Gene Sculpt Suite: a set of tools for genome editing

Mann, C. M., Martínez-Gálvez, G., Welker, J. M., Wierson, W. A., Ata, H., Almeida, M. P., Clark, K. J., Essner, J. J., McGrail, M., Ekker, S. C. & Dobbs, D., Jul 2 2019, In : Nucleic acids research. 47, W1, p. W175-W182

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018
3 Scopus citations

Fishing for understanding: Unlocking the zebrafish gene editor's toolbox

Simone, B. W., Martínez-Gálvez, G., WareJoncas, Z. & Ekker, S. C., Jan 1 2018, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

7 Scopus citations

Humidity as a non-pharmaceutical intervention for influenza A

Reiman, J. M., Das, B., Sindberg, G. M., Urban, M. D., Hammerlund, M. E. M., Lee, H. B., Spring, K. M., Lyman-Gingerich, J., Generous, A. R., Koep, T. H., Ewing, K., Lilja, P., Enders, F. T., Ekker, S. C., Huskins, W. C., Fadel, H. & Pierret, C. K., Sep 1 2018, In : PLoS One. 13, 9, e0204337.

Research output: Contribution to journalArticle

6 Scopus citations

Precision gene editing technology and applications in nephrology

WareJoncas, Z., Campbell, J. M., Martínez-Gálvez, G., Gendron, W. A. C., Barry, M. A., Harris, P. C., Sussman, C. R. & Ekker, S. C., Jan 1 2018, (Accepted/In press) In : Nature Reviews Nephrology.

Research output: Contribution to journalArticle

7 Scopus citations

Robust activation of microhomology-mediated end joining for precision gene editing applications

Ata, H., Ekstrom, T. L., Martínez-Gálvez, G., Mann, C. M., Dvornikov, A. V., Schaefbauer, K. J., Ma, A. C., Dobbs, D., Clark, K. J. & Ekker, S. C., Sep 1 2018, In : PLoS Genetics. 14, 9, e1007652.

Research output: Contribution to journalArticle

6 Scopus citations

tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish

Ignatius, M. S., Hayes, M. N., Moore, F. E., Tang, Q., Garcia, S. P., Blackburn, P. R., Baxi, K., Wang, L., Jin, A., Ramakrishnan, A., Reeder, S., Chen, Y., Nielsen, G. P., Chen, E. Y., Hasserjian, R. P., Tirode, F., Ekker, S. C. & Langenau, D. M., Sep 7 2018, In : eLife. 7

Research output: Contribution to journalArticle

9 Scopus citations
2017

A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene

Ding, Y., Long, P. A., Bos, J. M., Shih, Y. H., Ma, X., Sundsbak, R. S., Chen, J., Jiang, Y., Zhao, L., Hu, X., Wang, J., Shi, Y., Ackerman, M. J., Lin, X., Ekker, S. C., Redfield, M. M., Olson, T. M. & Xu, X. H., Apr 20 2017, In : JCI insight. 2, 8

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly

El-Rass, S., Eisa-Beygi, S., Khong, E., Brand-Arzamendi, K., Mauro, A., Zhang, H., Clark, K. J., Ekker, S. C. & Wen, X. Y., Mar 15 2017, In : Biology Open. 6, 3, p. 348-357 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Guidelines for morpholino use in zebrafish

Stainier, D. Y. R., Raz, E., Lawson, N. D., Ekker, S. C., Burdine, R. D., Eisen, J. S., Ingham, P. W., Schulte-Merker, S., Yelon, D., Weinstein, B. M., Mullins, M. C., Wilson, S. W., Ramakrishnan, L., Amacher, S. L., Neuhauss, S. C. F., Meng, A., Mochizuki, N., Panula, P. & Moens, C. B., Oct 1 2017, In : PLoS Genetics. 13, 10, e1007000.

Research output: Contribution to journalArticle

91 Scopus citations
2016

Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer

Zhao, Y., Wang, L., Ren, S., Wang, L., Blackburn, P. R., McNulty, M. S., Gao, X., Qiao, M., Vessella, R. L., Kohli, M., Zhang, J., Karnes, R. J., Tindall, D. J., Kim, Y., MacLeod, R., Ekker, S. C., Kang, T., Sun, Y. & Huang, H., Apr 19 2016, In : Cell Reports. 15, 3, p. 599-610 12 p.

Research output: Contribution to journalArticle

32 Scopus citations
6 Scopus citations

FusX: A rapid one-step transcription activator-like effector assembly system for genome science

Ma, A. C., Mcnulty, M. S., Poshusta, T. L., Campbell, J. M., Martínez-Gálvez, G., Argue, D. P., Lee, H. B., Urban, M. D., Bullard, C. E., Blackburn, P. R., Man, T. K., Clark, K. J. & Ekker, S. C., Jun 1 2016, In : Human Gene Therapy. 27, 6, p. 451-463 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

GoldyTALEN vectors with improved efficiency for golden gate TALEN assembly

Welker, J. M., Wierson, W. A., Wang, Y., Poshusta, T. L., Mcnulty, M. S., Tisdale, E. E., Solin, S. L., Ekker, S. C., Clark, K. J., Mcgrail, M. & Essner, J. J., Jun 1 2016, In : Human Gene Therapy. 27, 6, p. 423-424 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mayo Clinic Zebrafish Facility Overview

Leveque, R. E., Clark, K. J. & Ekker, S. C., Jul 1 2016, In : Zebrafish. 13, p. S44-S46

Research output: Contribution to journalArticle

3 Scopus citations

Students being and becoming scientists: Measured success in a novel science education partnership

Yang, J., Labounty, T. J., Ekker, S. C. & Pierret, C. K., Jan 1 2016, In : Palgrave Communications. 2, 16005.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Etv2 and Fli1b function together as key regulators of vasculogenesis and angiogenesis

Craig, M. P., Grajevskaja, V., Liao, H. K., Balciuniene, J., Ekker, S. C., Park, J. S., Essner, J. J., Balciunas, D. & Sumanas, S., Apr 27 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 4, p. 865-876 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Protein-trap insertional mutagenesis uncovers new genes involved in zebrafish skin development, including a Neuregulin 2a-based ErbB signaling pathway required during median fin fold morphogenesis

Westcot, S. E., Hatzold, J., Urban, M. D., Richetti, S. K., Skuster, K. J., Harm, R. M., Cervera, R. L., Umemoto, N., McNulty, M. S., Clark, K. J., Hammerschmidt, M. & Ekker, S. C., Jun 25 2015, In : PLoS One. 10, 6, e0130688.

Research output: Contribution to journalArticle

10 Scopus citations

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Hoeppner, L. H., Sinha, S., Wang, Y., Bhattacharya, R., Dutta, S., Gong, X., Bedell, V. M., Suresh, S., Chun, C., Ramchandran, R., Ekker, S. C. & Mukhopadhyay, D., 2015, In : Journal of Cell Science. 128, 19, p. 3556-3568 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Using engineered endonucleases to create knockout and knockin zebrafish models

Bedell, V. M. & Ekker, S. C., 2015, In : Methods in Molecular Biology. 1239, p. 291-306 16 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Detection of 1α,25-dihydroxyvitamin D-regulated miRNAs in zebrafish by whole transcriptome sequencing

Craig, T. A., Zhang, Y., Magis, A. T., Funk, C. C., Price, N. D., Ekker, S. C. & Kumar, R., Jun 1 2014, In : Zebrafish. 11, 3, p. 207-218 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Influenza Knowledge, Attitude, and Behavior Survey for Grade School Students: Design and Novel Assessment Methodology

Koep, T. H., Huskins, W. C., Clemens, C., Jenkins, S., Pierret, C. K., Ekker, S. C. & Enders, F. T., Oct 31 2014, In : Journal of Community Health. 39, 6, p. 1231-1240 10 p.

Research output: Contribution to journalArticle

In vivo orientation of single myosin lever arms in zebrafish skeletal muscle

Sun, X., Ekker, S. C., Shelden, E. A., Takubo, N., Wang, Y. & Burghardt, T. P., Sep 16 2014, In : Biophysical Journal. 107, 6, p. 1403-1414 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Larval zebrafish model for FDA-approved drug repositioning for tobacco dependence treatment

Cousin, M. A., Ebbert, J. O., Wiinamaki, A. R., Urban, M. D., Argue, D. P., Ekker, S. C. & Klee, E. W., Mar 21 2014, In : PLoS One. 9, 3, e90467.

Research output: Contribution to journalArticle

21 Scopus citations

Making designer mutants in model organisms

Peng, Y., Clark, K. J., Campbell, J. M., Panetta, M. R., Guo, Y. D. & Ekker, S. C., Nov 1 2014, In : Development (Cambridge). 141, 21, p. 4042-4054 13 p.

Research output: Contribution to journalArticle

71 Scopus citations

TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism

Fadel, H., Morrison, J. H., Saenz, D. T., Fuchs, J. R., Kvaratskhelia, M., Ekker, S. C. & Poeschla, E. M., Sep 1 2014, In : Journal of Virology. 88, 17, p. 9704-9717 14 p.

Research output: Contribution to journalArticle

49 Scopus citations

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells

Wu, X., Blackburn, P. R., Tschumper, R. C., Ekker, S. C. & Jelinek, D. F., 2014, In : Blood Cancer Journal. 4, 5, 210.

Research output: Contribution to journalArticle

8 Scopus citations

The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation.

Singh, M., Bhartiya, D., Maini, J., Sharma, M., Singh, A. R., Kadarkaraisamy, S., Rana, R., Sabharwal, A., Nanda, S., Ramachandran, A., Mittal, A., Kapoor, S., Sehgal, P., Asad, Z., Kaushik, K., Vellarikkal, S. K., Jagga, D., Muthuswami, M., Chauhan, R. K., Leonard, E. & 27 others, Priyadarshini, R., Halimani, M., Malhotra, S., Patowary, A., Vishwakarma, H., Joshi, P., Bhardwaj, V., Bhaumik, A., Bhatt, B., Jha, A., Kumar, A., Budakoti, P., Lalwani, M. K., Meli, R., Jalali, S., Joshi, K., Pal, K., Dhiman, H., Laddha, S. V., Jadhav, V., Singh, N., Pandey, V., Sachidanandan, C., Ekker, S. C., Klee, E. W., Scaria, V. & Sivasubbu, S., 2014, In : Database : the journal of biological databases and curation. 2014

Research output: Contribution to journalArticle

6 Scopus citations
2013

Anovel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression

Khurana, S., Buckley, S., Schouteden, S., Ekker, S. C., Petryk, A., Delforge, M., Zwijsen, A. & Verfaillie, C. M., Jan 31 2013, In : Blood. 121, 5, p. 781-790 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

A sequence-based variation map of zebrafish

Patowary, A., Purkanti, R., Singh, M., Chauhan, R., Singh, A. R., Swarnkar, M., Singh, N., Pandey, V., Torroja, C., Clark, M. D., Kocher, J-P., Clark, K. J., Stemple, D. L., Klee, E. W., Ekker, S. C., Scaria, V. & Sivasubbu, S., Mar 1 2013, In : Zebrafish. 10, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
37 Scopus citations

Mojo Hand, a TALEN design tool for genome editing applications

Neff, K. L., Argue, D. P., Ma, A. C., Lee, H. B., Clark, K. J. & Ekker, S. C., Jan 16 2013, In : BMC Bioinformatics. 14, 1, 1.

Research output: Contribution to journalArticle

55 Scopus citations

New and TALENted genome engineering toolbox

Campbell, J. M., Hartjes, K. A., Nelson, T. J., Xu, X. H. & Ekker, S. C., Aug 16 2013, In : Circulation Research. 113, 5, p. 571-587 17 p.

Research output: Contribution to journalArticle

30 Scopus citations
18 Scopus citations
30 Scopus citations

The CRISPR system - Keeping zebrafish gene targeting fresh

Blackburn, P. R., Campbell, J. M., Clark, K. J. & Ekker, S. C., Mar 1 2013, In : Zebrafish. 10, 1, p. 116-118 3 p.

Research output: Contribution to journalArticle

64 Scopus citations

The zebrafish as a model to study polycystic liver disease

Tietz Bogert, P. S., Huang, B. Q., Gradilone, S. A., Masyuk, T. V., Moulder, G. L., Ekker, S. C. & La Russo, N. F., Jun 1 2013, In : Zebrafish. 10, 2, p. 211-217 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
20 Scopus citations
2012

An In Vivo Method to Quantify Lymphangiogenesis in Zebrafish

Hoffman, S. J., Psaltis, P. J., Clark, K. J., Spoon, D. B., Chue, C. D., Ekker, S. C. & Simari, R. D., Sep 13 2012, In : PLoS One. 7, 9, e45240.

Research output: Contribution to journalArticle

4 Scopus citations

Expression of sclerostin in the developing zebrafish (Danio rerio) brain and skeleton

McNulty, M. S., Bedell, V. M., Greenwood, T. M., Craig, T. A., Ekker, S. C. & Kumar, R., Aug 2012, In : Gene Expression Patterns. 12, 7-8, p. 228-235 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
15 Scopus citations

Nervy vasculature.

Bedell, V. M. & Ekker, S. C., Jul 2012, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 7, p. 1546-1547 2 p.

Research output: Contribution to journalArticle

1 Scopus citations