• 5289 Citations
  • 36 Scopus h-Index
20032019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2003 2019

2019

Ability of dual-energy CT to detect silicone gel breast implant rupture and nodal silicone spread

Glazebrook, K. N., Doerge, S., Leng, S., Drees, T. A., Hunt, K. N., Zingula, S. N., Pruthi, S., Geske, J. R., Carter, R. E., McCollough, C. H. & Fletcher, J. G., Apr 1 2019, In : American Journal of Roentgenology. 212, 4, p. 933-942 10 p.

Research output: Contribution to journalArticle

Silicone Gels
Breast Implants
Silicones
Rupture
Breast
1 Citation (Scopus)

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT

Gong, H., Yu, L., Leng, S., Dilger, S. K., Ren, L., Zhou, W., Fletcher, J. G. & McCollough, C. H., Jan 1 2019, In : Medical physics.

Research output: Contribution to journalArticle

Least-Squares Analysis
Learning
Noise
Liver
Radiation

Automatic strategy for CHO channel reduction in x-ray angiography systems

Gomez-Cardona, D., Leng, S., Favazza, C. P., Schueler, B. A. & Fetterly, K. A., Jan 1 2019, Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment. Nishikawa, R. M. & Samuelson, F. W. (eds.). SPIE, 1095205. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10952).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Angiography
angiography
X-Rays
Noise
X rays

Clinical utility of virtual noncalcium dual-energy CT in imaging of the pelvis and hip

Baffour, F. I., Glazebrook, K. N., Morris, J. M., Michalak, G. J., Fletcher, J. G., Leng, S. & McCollough, C. H., Jan 1 2019, In : Skeletal Radiology.

Research output: Contribution to journalReview article

Pelvis
Hip
Bone Marrow
Pathology
Edema

Correlation between a deep-learning-based model observer and human observer for a realistic lung nodule localization task in chest CT

Gong, H., Walther, A., Hu, Q., Koo, C. W., Takahashi, E. A., Levin, D. L., Johnson, T., Hora, M. J., Leng, S., Fletcher, J. G., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment. Nishikawa, R. M. & Samuelson, F. W. (eds.). SPIE, 109520K. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10952).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

chest
nodules
lungs
learning
Thorax

Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential

Shanblatt, E. R., Nelson, B. J., Tao, S., Leng, S. & McCollough, C. H., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482W. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

x ray tubes
fats
Interferometers
Demonstrations
interferometers
1 Citation (Scopus)
Cryosurgery
Ice
Pelvis
Spine
Tomography
1 Citation (Scopus)

Dual-source photon counting detector CT with a tin filter: a phantom study on iodine quantification performance

Tao, A., Huang, R., Tao, S., Michalak, G. J., McCollough, C. H. & Leng, S., May 31 2019, In : Physics in medicine and biology. 64, 11, 1 p.

Research output: Contribution to journalArticle

Tin
Photons
Iodine
Research Design
Least-Squares Analysis
Photons
Gadolinium
Bismuth
Noise
Head

Forward model for propagation-based X-ray phase contrast imaging in parallel- and conebeam geometry

Shanblatt, E. R., Sung, Y., Gupta, R., Nelson, B. J., Leng, S., Graves, W. S. & McCollough, C. H., Jan 1 2019, In : Optics Express. 27, 4, p. 4504-4521 18 p.

Research output: Contribution to journalArticle

phase contrast
propagation
geometry
x rays
cones
2 Citations (Scopus)

High-Resolution Chest Computed Tomography Imaging of the Lungs: Impact of 1024 Matrix Reconstruction and Photon-Counting Detector Computed Tomography

Bartlett, D. J., Koo, C. W., Bartholmai, B. J., Rajendran, K., Weaver, J. M., Halaweish, A. F., Leng, S., McCollough, C. H. & Fletcher, J. G., Mar 1 2019, In : Investigative Radiology. 54, 3, p. 129-137 9 p.

Research output: Contribution to journalArticle

Photons
Bronchi
Thorax
Tomography
Lung
Iodine
Noise
Photons
X-Rays
Whole-Body Counting
1 Citation (Scopus)
Liver
Water
Noise
Computer-Assisted Image Processing
ROC Curve
Theoretical Models
Liver
Water
Task Performance and Analysis
ROC Curve

Multi-contrast imaging on dual-source photon-counting-detector (PCD) CT

Tao, S., Rajendran, K., McCollough, C. H. & Leng, S., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484L. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photons
Light sources
counting
Detectors
Imaging techniques

Optimal acquisition setting for dual-contrast imaging with gadolinium and iodine on a research whole-body photon-counting-detector (PCD) CT

Tao, S., Wu, Y., Rajendran, K., McCollough, C. H. & Leng, S., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484I. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Whole-Body Counting
Gadolinium
gadolinium
Iodine
Photons
1 Citation (Scopus)

Photon-counting detector CT: System design and clinical applications of an emerging technology

Leng, S., Bruesewitz, M., Tao, S., Rajendran, K., Halaweish, A. F., Campeau, N. G., Fletcher, J. G. & McCollough, C. H., May 1 2019, In : Radiographics. 39, 3, p. 729-743 15 p.

Research output: Contribution to journalArticle

Photons
Technology
Contrast Media
Artifacts
Noise

Quantitative cartilage imaging using spectral photon-counting detector based computed tomography

Rajendran, K., Tao, S., Benike, A., Leng, S. & McCollough, C. H., Jan 1 2019, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging. Gimi, B. & Krol, A. (eds.). SPIE, 109531A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10953).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

cartilage
Cartilage
Glycosaminoglycans
Photons
Tomography

Reducing radiation dose for multi-phase contrast-enhanced dual energy renal CT: pilot study evaluating prior iterative reconstruction

Navin, P. J., Kim, B., Wells, M., Khandelwal, A., Halaweish, A. F., Moen, T. R., Johnson, M. P., McCollough, S., Lee, Y. S., Leng, S., McCollough, C. H. & Fletcher, J. G., Jan 1 2019, (Accepted/In press) In : Abdominal Radiology.

Research output: Contribution to journalArticle

Radiation
Kidney
Computer-Assisted Image Processing
Neoplasms
Kidney Neoplasms
3 Citations (Scopus)

Reduction of Metal Artifacts and Improvement in Dose Efficiency Using Photon-Counting Detector Computed Tomography and Tin Filtration

Zhou, W., Bartlett, D. J., Diehn, F. E., Glazebrook, K. N., Kotsenas, A. L., Carter, R. E., Fletcher, J. G., McCollough, C. H. & Leng, S., Apr 1 2019, In : Investigative radiology. 54, 4, p. 204-211 8 p.

Research output: Contribution to journalArticle

Tin
Photons
Artifacts
Metals
Tomography

Simulation of CT images reconstructed with different kernels using a convolutional neural network and its implications for efficient CT workflow

Missert, A. D., Leng, S., McCollough, C. H., Fletcher, J. G. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Workflow
Tomography
tomography
X-Ray Computed Tomography Scanners
Neural networks

Visibility guided phase contrast denoising

Nelson, B., Koenig, T., Shanblatt, E., Leng, S. & McCollough, C. H., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Interferometry
phase contrast
visibility
Visibility
low visibility
2018
13 Citations (Scopus)

150-μm Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images

Leng, S., Rajendran, K., Gong, H., Zhou, W., Halaweish, A. F., Henning, A., Kappler, S., Baer, M., Fletcher, J. G. & McCollough, C. H., Nov 1 2018, In : Investigative Radiology. 53, 11, p. 655-662 8 p.

Research output: Contribution to journalArticle

Photons
Tomography
Technology
Noise
Research Ethics Committees
2 Citations (Scopus)

Characterization of Urinary Stone Composition by Use of Whole-body, Photon-counting Detector CT

Ferrero, A., Gutjahr, R., Halaweish, A. F., Leng, S. & McCollough, C. H., Jan 1 2018, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Whole-Body Counting
Urinary Calculi
Photons
Tomography
ROC Curve
2 Citations (Scopus)

Comparison of a photon-counting-detector CT with an energy-integrating-detector CT for temporal bone imaging: A cadaveric study

Zhou, W., Lane, J. I., Carlson, M. L., Bruesewitz, M. R., Witte, R. J., Koeller, K. K., Eckel, L. J., Carter, R. E., McCollough, C. H. & Leng, S., Sep 1 2018, In : American Journal of Neuroradiology. 39, 9, p. 1733-1738 6 p.

Research output: Contribution to journalArticle

Temporal Bone
Photons
Stapes
Comb and Wattles
Anatomy

Composite materials for 3D printing of medical phantoms

Abdel-Magid, B. M., VanOosten, D., Vrieze, T. & Leng, S., Jan 1 2018.

Research output: Contribution to conferencePaper

Printing
Stainless Steel
Powders
Bone
Composite materials
1 Citation (Scopus)

Correlation between model observers in uniform background and human observers in patient liver background for a low-contrast detection task in CT

Gong, H., Yu, L., Leng, S., DIlger, S., Zhou, W., Ren, L. & McCollough, C. H., Jan 1 2018, Medical Imaging 2018: Image Perception, Observer Performance, and Technology Assessment. SPIE, Vol. 10577. 105770M

Research output: Chapter in Book/Report/Conference proceedingConference contribution

liver
Liver
lesions
Computerized tomography
Image quality
5 Citations (Scopus)

Detection and characterization of renal stones by using photon-counting-based CT

Marcus, R. P., Fletcher, J. G., Ferrero, A., Leng, S., Halaweish, A. F., Gutjahr, R., Vrtiska, T. J., Wells, M., Enders, F. T. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 436-442 7 p.

Research output: Contribution to journalArticle

Photons
Kidney
Cone-Beam Computed Tomography
Uric Acid
Research
1 Citation (Scopus)

Determination of optimal image type and lowest detectable concentration for iodine detection on a photon counting detector-based multi-energy CT system

Zhou, W., Schornak, R., Michalak, G., Weaver, J., Abdurakhimova, D., Ferrero, A., Fetterly, K. A., McCollough, C. H. & Leng, S., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 105734U

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Iodine
Photons
iodine
low concentrations
counting
6 Citations (Scopus)

Dual-source multienergy CT with triple or quadruple x-ray beams

Yu, L., Ren, L., Li, Z., Leng, S. & McCollough, C. H., Jul 1 2018, In : Journal of Medical Imaging. 5, 3, 033502.

Research output: Contribution to journalArticle

Photons
X-Rays
Contrast Media
Computer Simulation
Noise

Evaluation of a photon counting Medipix3RX cadmium zinc telluride spectral x-ray detector

Marsh, J. F., Jorgensen, S. M., Rundle, D. S., Vercnocke, A. J., Leng, S., Butler, P. H., McCollough, C. H. & Ritman, E. L., Oct 1 2018, In : Journal of Medical Imaging. 5, 4, 043503.

Research output: Contribution to journalArticle

X-Ray Microtomography
Photons
X-Rays
Brachytherapy
Linear Models
2 Citations (Scopus)

Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study

Long, Z., Bruesewitz, M. R., Delone, D. R., Morris, J. M., Amrami, K. K., Adkins, M. C., Glazebrook, K. N., Kofler, J. M., Leng, S., McCollough, C. H., Fletcher, J. G., Halaweish, A. F. & Yu, L., Jan 1 2018, (Accepted/In press) In : Journal of Applied Clinical Medical Physics.

Research output: Contribution to journalArticle

Artifacts
artifacts
projection
Metals
evaluation
1 Citation (Scopus)

Imaging findings of mammary and systemic silicone deposition secondary to breast implants

Samreen, N., Glazebrook, K. N., Bhatt, A., Venkatesh, S. K., Mcmenomy, B. P., Chandra, A., Leng, S., Adler, K. E. & McCollough, C. H., Jan 1 2018, In : British Journal of Radiology. 91, 1089, 20180098.

Research output: Contribution to journalReview article

Breast Implants
Silicones
Breast
Rupture
Spleen

Impact of Effective Detector Pixel and CT Voxel Size on Accurate Estimation of Blood Volume in Opacified Microvasculature

Sheikhzadeh, M., Vercnocke, A. J., Tao, S., Rajendran, K., Leng, S., Ritman, E. L. & McCollough, C. H., Jan 1 2018, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Microvessels
Blood Volume
Photons
Swine
X-Ray Microtomography
1 Citation (Scopus)

Impact of photon counting detector technology on kV selection and diagnostic workflow in CT

Zhou, W., Abdurakhimova, D., Bruesewitz, M., Halaweish, A., McCollough, C. H. & Leng, S., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 105731C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Workflow
Iodine
Photons
Noise
counting
5 Citations (Scopus)

Material decomposition with prior knowledge aware iterative denoising (MD-PKAID)

Tao, S., Rajendran, K., McCollough, C. H. & Leng, S., Sep 21 2018, In : Physics in Medicine and Biology. 63, 19, 195003.

Research output: Contribution to journalArticle

Noise
Whole-Body Counting
Least-Squares Analysis
Photons
Iodine
2 Citations (Scopus)

Observer performance with varying radiation dose and reconstruction methods for detection of hepatic metastases

Fletcher, J. G., Fidler, J. L., Venkatesh, S. K., Hough, D. M., Takahashi, N. M., Yu, L., Johnson, M., Leng, S., Holmes III, D. R., Carter, R. E. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 455-464 10 p.

Research output: Contribution to journalArticle

Radiation
Neoplasm Metastasis
Liver
ROC Curve
Cone-Beam Computed Tomography

Radiation dose in CT-guided interventional procedures: Establishing a benchmark

Leng, S., Oct 1 2018, In : Radiology. 289, 1, p. 158-159 2 p.

Research output: Contribution to journalEditorial

Benchmarking
Radiation

Ultra-high resolution photon-counting detector CT reconstruction using spectral prior image constrained compressed-sensing (UHR-SPICCS)

Rajendran, K., Tao, S., Abdurakhimova, D., Leng, S. & McCollough, C. H., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 1057318

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Compressed sensing
Photons
counting
Noise
Detectors
2017
1 Citation (Scopus)
Calculi
Swine
Radiation
Kidney
X-Ray Computed Tomography Scanners
9 Citations (Scopus)

An effective noise reduction method for multi-energy CT images that exploit spatio-spectral features

Li, Z., Leng, S., Yu, L., Manduca, A. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1610-1623 14 p.

Research output: Contribution to journalArticle

Noise
Cadaver
Radiology
Swine
Head
3 Citations (Scopus)

A virtual clinical trial using projection-based nodule insertion to determine radiologist reader performance in lung cancer screening CT

Yu, L., Hu, Q., Koo, C. W., Takahashi, E. A., Levin, D. L., Johnson, T., Hora, M. J., Dirks, S., Chen, B., McMillan, K., Leng, S., Fletcher, J. G. & McCollough, C. H., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101321R

Research output: Chapter in Book/Report/Conference proceedingConference contribution

nodules
readers
Early Detection of Cancer
lungs
insertion
2 Citations (Scopus)

Cochlear Implant Electrode Localization Using an Ultra-High Resolution Scan Mode on Conventional 64-Slice and New Generation 192-Slice Multi-Detector Computed Tomography

Carlson, M. L., Leng, S., Diehn, F. E., Witte, R. J., Krecke, K. N., Grimes, J., Koeller, K. K., Bruesewitz, M. R., McCollough, C. H. & Lane, J. I., May 31 2017, (Accepted/In press) In : Otology and Neurotology.

Research output: Contribution to journalArticle

Cochlear Implants
X-Ray Computed Tomography Scanners
Electrodes
Tomography
Artifacts
1 Citation (Scopus)

Consistency of renal stone volume measurements across CT scanner model and reconstruction algorithm configurations

Huang, A. E., Montoya, J. C., Shiung, M., Leng, S. & McCollough, C. H., Jul 1 2017, In : American Journal of Roentgenology. 209, 1, p. 116-121 6 p.

Research output: Contribution to journalArticle

Kidney Calculi
Kidney
Prospective Studies
12 Citations (Scopus)

Correlation between a 2D channelized Hotelling observer and human observers in a low-contrast detection task with multislice reading in CT

Yu, L., Chen, B., Kofler, J. M., Favazza, C. P., Leng, S., Kupinski, M. A. & McCollough, C. H., Aug 1 2017, In : Medical Physics. 44, 8, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

Reading
Confidence Intervals
Radiation

Detection of increased vasa vasorum in artery walls: Improving CT number accuracy using image deconvolution

Rajendran, K., Leng, S., Jorgensen, S. M., Abdurakhimova, D., Ritman, E. L. & McCollough, C. H., Feb 3 2017, In : Proceedings of SPIE - The International Society for Optical Engineering. 10327, 135.

Research output: Contribution to journalConference article

Deconvolution
Arteries
arteries
2 Citations (Scopus)

Detection of increased vasa vasorum in artery walls: Improving CT number accuracy using image deconvolution

Rajendran, K., Leng, S., Jorgensen, S. M., Abdurakhimova, D., Ritman, E. L. & McCollough, C. H., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101323O

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vasa Vasorum
Deconvolution
arteries
Tomography
Arteries
2 Citations (Scopus)

Dual energy CT kidney stone differentiation in photon counting computed tomography

Gutjahr, R., Polster, C., Henning, A., Kappler, S., Leng, S., McCollough, C. H., Sedlmair, M. U., Schmidt, B., Krauss, B. & Flohr, T. G., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 1013237

Research output: Chapter in Book/Report/Conference proceedingConference contribution

kidney stones
Apatites
Calcium Oxalate
Kidney Calculi
Apatite
10 Citations (Scopus)

Estimating patient dose from CT exams that use automatic exposure control: Development and validation of methods to accurately estimate tube current values

Mcmillan, K., Bostani, M., Cagnon, C. H., Yu, L., Leng, S., McCollough, C. H. & Mcnitt-Gray, M. F., 2017, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Pelvis
Abdomen
Thorax
Breast
Spleen