Saravut (John) Weroha

2024

What's in your “lunchbox”? Sandwich versus sequential chemotherapy and irradiation for advanced endometrial cancer

Glaser, G. & Weroha, J., Jan 2024, In: Gynecologic oncology. 180, p. A1-A2

Research output: Contribution to journal › Editorial › peer-review

2023

Characterization and Optimization of Multiomic Single-Cell Epigenomic Profiling

Sandoval, L., Mohammed Ismail, W., Mazzone, A., Dumbrava, M., Fernandez, J., Munankarmy, A., Lasho, T., Binder, M., Simon, V., Kim, K. H., Chia, N., Lee, J. H., Weroha, S. J., Patnaik, M. & Gaspar-Maia, A., Jun 2023, In: Genes. 14, 6, 1245.

Research output: Contribution to journal › Article › peer-review

Open Access

Epigenomics may begin to explain in vitro differential response to hypomethylating agents in MMR-D hypermethylated endometrial cancer

El Khoury, L. Y., Lin, W. H., Smadbeck, J. B., Barrett, M. T., Sadeghian, D., Mccune, A. F., Karagouga, G., Cheville, J. C., Harris, F. R., Kinsella, L. M., Feathers, R. W., Schafer Klein, J. L., Walther-Antonio, M. R. S., Johnson, S. H., Penheiter, A. R., Cucinella, G., Schivardi, G., Bhagwate, A., Borad, M. J., Mansfield, A. S., & 6 othersMurphy, S. J., Mariani, A., Vasmatzis, G., Anastasiadis, P. Z., Weroha, S. J. & Larish, A. M., Mar 1 2023, In: Epigenomics. 15, 5, p. 283-292 10 p.

Research output: Contribution to journal › Article › peer-review

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C

Hu, C., Nagaraj, A. B., Shimelis, H., Montalban, G., Lee, K. Y., Huang, H., Lumby, C. A., Na, J., Susswein, L. R., Roberts, M. E., Marshall, M. L., Hiraki, S., LaDuca, H., Chao, E., Yussuf, A., Pesaran, T., Neuhausen, S. L., Haiman, C. A., Kraft, P., Lindstrom, S., & 24 othersPalmer, J. R., Teras, L. R., Vachon, C. M., Yao, S., Ong, I., Nathanson, K. L., Weitzel, J. N., Boddicker, N., Gnanaolivu, R., Polley, E. C., Mer, G., Cui, G., Karam, R., Richardson, M. E., Domchek, S. M., Yadav, S., Hruska, K. S., Dolinsky, J., Weroha, S. J., Hart, S. N., Simard, J., Masson, J. Y., Pang, Y. P. & Couch, F. J., Aug 1 2023, In: Cancer research. 83, 15, p. 2557-2571 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Incidence of venous thromboembolism in patients with advanced stage ovarian cancer undergoing neoadjuvant chemotherapy: Is it time for thromboprophylaxis?

Shafa, A., Watkins, A. B., McGree, M. E., Weroha, S. J., Wahner Hendrickson, A. E., Block, M. S., Langstraat, C. L., McBane, R. D., Bakkum-Gamez, J. N. & Kumar, A., Sep 2023, In: Gynecologic oncology. 176, p. 36-42 7 p.

Research output: Contribution to journal › Article › peer-review

Prognostic stratification of endometrial cancers with high microsatellite instability or no specific molecular profile

Gonzalez-Bosquet, J., Weroha, S. J., Bakkum-Gamez, J. N., Weaver, A. L., McGree, M. E., Dowdy, S. C., Famuyide, A. O., Kipp, B. R., Halling, K. C., Yadav, S., Couch, F. J. & Podratz, K. C., 2023, In: Frontiers in Oncology. 13, 1105504.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Combination therapy with decitabine and olaparib in poly(ADP-ribose) polymerase inhibitor (PARPi) resistant high grade serous ovarian cancer

Shafa, A., Hou, X., Wang, L. & Weroha, S. J., Oct 2022, In: European Journal of Cancer. 174, p. S54

Research output: Contribution to journal › Article › peer-review

Open Access

DNA barcoded competitive clone-initiating cell analysis reveals novel features of metastatic growth in a cancer xenograft model

Aalam, S. M. M., Tang, X., Song, J., Ray, U., Russell, S. J., Weroha, S. J., Bakkum-Gamez, J., Shridhar, V., Sherman, M. E., Eaves, C. J., Knapp, D. J. H. F., Kalari, K. R. & Kannan, N., Sep 1 2022, In: NAR Cancer. 4, 3, zcac022.

Research output: Contribution to journal › Article › peer-review

Open Access

ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer

Gonzalez-Bosquet, J., John Weroha, S., Bakkum-Gamez, J. N., Weaver, A. L., McGree, M. E., Dowdy, S. C., Famuyide, A. O., Kipp, B. R., Halling, K. C., Yadav, S., Couch, F. J. & Podratz, K. C., Dec 2022, In: PloS one. 17, 12 December, e0278408.

Research output: Contribution to journal › Article › peer-review

Open Access

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Scottish Genomes Partnership & Australian Ovarian Cancer Study, Dec 1 2022, In: Cancer research. 82, 23, p. 4457-4473 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High glucocorticoid receptor expression in the sarcomatous versus carcinomatous elements of Mullerian carcinosarcomas

Kurnit, K. C., Steiner, M., Lastra, R. R., Weroha, S. J., Cursio, J., Lengyel, E., Fleming, G. F. & Conzen, S. D., Jun 2022, In: Gynecologic Oncology Reports. 41, 100987.

Research output: Contribution to journal › Article › peer-review

Open Access

Machine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors

Cotler, M. J., Ramadi, K. B., Hou, X., Christodoulopoulos, E., Ahn, S., Bashyam, A., Ding, H., Larson, M., Oberg, A. L., Whittaker, C., Jonas, O., Kaufmann, S. H., Weroha, S. J. & Cima, M. J., Jul 2022, In: Translational Oncology. 21, 101427.

Research output: Contribution to journal › Article › peer-review

Open Access

Non-gestational choriocarcinoma with hyperprogression on pembrolizumab: A case report and review of the literature

Kazemi, N. Y., Langstraat, C. & John Weroha, S., Feb 2022, In: Gynecologic Oncology Reports. 39, 100923.

Research output: Contribution to journal › Article › peer-review

Open Access

Not all stage I and II endometrial cancers are created equal: Recurrence-free survival and cause-specific survival after observation or vaginal brachytherapy alone in all subgroups of early-stage high-intermediate and high-risk endometrial cancer

Garzon, S., Grassi, T., Mariani, A., Kollikonda, S., Weaver, A. L., McGree, M. E., Petersen, I. A., Weroha, S. J., Glaser, G. E., Langstraat, C. L., Amarnath, S. R. & AlHilli, M. M., Dec 2022, In: Gynecologic oncology. 167, 3, p. 444-451 8 p.

Research output: Contribution to journal › Article › peer-review

Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma

Kanakkanthara, A., Hou, X., Ekstrom, T. L., Zanfagnin, V., Huehls, A. M., Kelly, R. L., Ding, H., Larson, M. C., Vasmatzis, G., Oberg, A. L., Kaufmann, S. H., Mansfield, A. S., Weroha, S. J. & Karnitz, L. M., Jan 15 2022, In: Cancer research. 82, 2, p. 307-319 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer

Ding, D., Zheng, R., Tian, Y., Jimenez, R., Hou, X., Weroha, S. J., Wang, L., Shi, L. & Huang, H., Dec 2022, In: Nature communications. 13, 1, 6311.

Research output: Contribution to journal › Article › peer-review

Open Access

Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer

Ray, U., Jung, D. B., Jin, L., Xiao, Y., Dasari, S., Bhattacharya, S. S., Thirusangu, P., Staub, J. K., Roy, D., Roy, B., Weroha, S. J., Hou, X., Purcell, J. W., Bakkum-Gamez, J. N., Kaufmann, S. H., Kannan, N., Mitra, A. K. & Shridhar, V., Mar 15 2022, In: Cancer research. 82, 6, p. 1038-1054 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Acquired RAD51C promoter methylation loss causes PARP inhibitor resistance in high-grade serous ovarian carcinoma

Nesic, K., Kondrashova, O., Hurley, R. M., McGehee, C. D., Vandenberg, C. J., Ho, G. Y., Lieschke, E., Dall, G., Bound, N., Shield-Artin, K., Radke, M., Musafer, A., Chai, Z. Q., Ghamsari, M. R. E., Harrell, M. I., Kee, D., Olesen, I., McNally, O., Traficante, N., DeFazio, A., & 9 othersBowtell, D. D. L., Swisher, E. M., Weroha, S. J., Nones, K., Waddell, N., Kaufmann, S. H., Dobrovic, A., Wakefield, M. J. & Scott, C. L., Sep 15 2021, In: Cancer research. 81, 18, p. 4709-4772 64 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options

Bosquet, J. G., Zhang, Q., Cliby, W. A., Bakkum-Gamez, J. N., Cen, L., Dowdy, S. C., Sherman, M. E., Weroha, S. J., Clayton, A. C., Kipp, B. R., Halling, K. C., Couch, F. J. & Podratz, K. C., Jan 2021, In: PloS one. 16, 1 January, e0245664.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance

Hurley, R. M., McGehee, C. D., Nesic, K., Correia, C., Weiskittel, T. M., Kelly, R. L., Venkatachalam, A., Hou, X., Pathoulas, N. M., Meng, X. W., Kondrashova, O., Radke, M. R., Schneider, P. A., Flatten, K. S., Peterson, K. L., Becker, M. A., Wong, E. M., Southey, M. S., Dobrovic, A., Lin, K. K., & 13 othersHarding, T. C., McNeish, I., Ross, C. A., Wagner, J. M., Wakefield, M. J., Scott, C. L., Haluska, P., Hendrickson, A. E. W., Karnitz, L. M., Swisher, E. M., Li, H., John Weroha, S. & Kaufmann, S. H., Sep 1 2021, In: NAR Cancer. 3, 3, zcab028.

Research output: Contribution to journal › Article › peer-review

Open Access

Chfr and paclitaxel sensitivity of ovarian cancer

Wahner Hendrickson, A. E., Visscher, D. W., Hou, X., Goergen, K. M., Atkinson, H. J., Beito, T. G., Negron, V., Lingle, W. L., Bruzek, A. K., Hurley, R. M., Wagner, J. M., Flatten, K. S., Peterson, K. L., Schneider, P. A., Larson, M. C., Maurer, M. J., Kalli, K. R., Oberg, A. L., Weroha, S. J. & Kaufmann, S. H., Dec 1 2021, In: Cancers. 13, 23, 6043.

Research output: Contribution to journal › Article › peer-review

Open Access

Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer

Liu, D., Hou, X., Wu, W., Zafagnin, V., Li, Y., Correia, C., Zhao, Z., Zhao, C., Liu, Z., Zhang, T., Fang, Z., Wang, H., Xu, C., Weroha, S. J., Kaufmann, S. H. & Dai, H., Aug 2021, In: Cell Death and Disease. 12, 8, 789.

Research output: Contribution to journal › Article › peer-review

Open Access

Correction: Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer (Cell Death & Disease, (2021), 12, 8, (789), 10.1038/s41419-021-04073-0)

Liu, D., Hou, X., Wu, W., Zafagnin, V., Li, Y., Correia, C., Zhao, Z., Zhao, C., Liu, Z., Zhang, T., Fang, Z., Wang, H., Xu, C., Weroha, S. J., Kaufmann, S. H. & Dai, H., Nov 2021, In: Cell Death and Disease. 12, 11, 1002.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

DOCK7 protects against replication stress by promoting RPA stability on chromatin

Gao, M., Guo, G., Huang, J., Hou, X., Ham, H., Kim, W., Zhao, F., Tu, X., Zhou, Q., Zhang, C., Zhu, Q., Liu, J., Yan, Y., Xu, Z., Yin, P., Luo, K., Weroha, J., Deng, M., Billadeau, D. D. & Lou, Z., Apr 6 2021, In: Nucleic acids research. 49, 6, p. 3322-3337 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

FOXA1 overexpression suppresses interferon signaling and immune response in cancer

He, Y., Wang, L., Wei, T., Xiao, Y. T., Sheng, H., Su, H., Hollern, D. P., Zhang, X., Ma, J., Wen, S., Xie, H., Yan, Y., Pan, Y., Hou, X., Tang, X., Suman, V. J., Carter, J. M., Weinshilboum, R., Wang, L., Kalari, K. R., & 9 othersWeroha, S. J., Bryce, A. H., Boughey, J. C., Dong, H., Perou, C. M., Ye, D., Goetz, M. P., Ren, S. & Huang, H., Jul 2021, In: Journal of Clinical Investigation. 131, 14, e147025.

Research output: Contribution to journal › Article › peer-review

Open Access

Frequent POLE-driven hypermutation in ovarian endometrioid cancer revealed by mutational signatures in RNA sequencing

Davila, J. I., Chanana, P., Sarangi, V., Fogarty, Z. C., Weroha, S. J., Guo, R., Goode, E. L., Huang, Y. & Wang, C., Dec 2021, In: BMC medical genomics. 14, 1, 165.

Research output: Contribution to journal › Article › peer-review

Open Access

GAS7 deficiency promotes metastasis in MYCN-driven neuroblastoma

Dong, Z., Yeo, K. S., Lopez, G., Zhang, C., Dankert Eggum, E. N., Rokita, J. L., Ung, C. Y., Levee, T. M., Her, Z. P., Howe, C. J., Hou, X., van Ree, J. H., Li, S., He, S., Tao, T., Fritchie, K., Torres-Mora, J., Lehman, J. S., Meves, A., Razidlo, G. L., & 8 othersRathi, K. S., Weroha, S. J., Look, A. T., van Deursen, J. M., Li, H., Westendorf, J. J., Maris, J. M. & Zhu, S., Jun 1 2021, In: Cancer research. 81, 11, p. 2995-3007 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness

Zhao, Y., Weroha, S. J., Goode, E. L., Liu, H. & Wang, C., Dec 2021, In: BMC Medical Informatics and Decision Making. 21, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer

Huang, D., Chowdhury, S., Wang, H., Savage, S. R., Ivey, R. G., Kennedy, J. J., Whiteaker, J. R., Lin, C., Hou, X., Oberg, A. L., Larson, M. C., Eskandari, N., Delisi, D. A., Gentile, S., Huntoon, C. J., Voytovich, U. J., Shire, Z. J., Yu, Q., Gygi, S. P., Hoofnagle, A. N., & 10 othersHerbert, Z. T., Lorentzen, T. D., Calinawan, A., Karnitz, L. M., Weroha, S. J., Kaufmann, S. H., Zhang, B., Wang, P., Birrer, M. J. & Paulovich, A. G., Dec 21 2021, In: Cell Reports Medicine. 2, 12, 100471.

Research output: Contribution to journal › Article › peer-review

Open Access

Nicotinamide mononucleotide prevents cisplatin-induced cognitive impairments

Yoo, K. H., Tang, J. J., Rashid, M. A., Cho, C. H., Corujo-Ramirez, A., Choi, J., Bae, M. G., Brogren, D., Hawse, J. R., Hou, X., John Weroha, S., Oliveros, A., Kirkeby, L. A., Baur, J. A. & Jang, M. H., Jul 1 2021, In: Cancer research. 81, 13, p. 3727-3737 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair

Abeykoon, J. P., Wu, X., Nowakowski, K. E., Dasari, S., Paludo, J., Weroha, S. J., Hu, C., Hou, X., Sarkaria, J. N., Mladek, A. C., Phillips, J. L., Feldman, A. L., Ravindran, A., King, R. L., Boysen, J., Stenson, M. J., Carr, R. M., Manske, M. K., Molina, J. R., Kapoor, P., & 10 othersParikh, S. A., Kumar, S., Robinson, S. I., Yu, J., Boughey, J. C., Wang, L., Goetz, M. P., Couch, F. J., Patnaik, M. M. & Witzig, T. E., Jan 28 2021, In: Blood. 137, 4, p. 513-523 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

SPOP mutation induces DNA methylation via stabilizing GLP/G9a

Zhang, J., Gao, K., Xie, H., Wang, D., Zhang, P., Wei, T., Yan, Y., Pan, Y., Ye, W., Chen, H., Shi, Q., Li, Y., Zhao, S. M., Hou, X., Weroha, S. J., Wang, Y., Zhang, J., Karnes, R. J., He, H. H., Wang, L., & 2 othersWang, C. & Huang, H., Dec 1 2021, In: Nature communications. 12, 1, 5716.

Research output: Contribution to journal › Article › peer-review

Open Access

Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting

Oberg, A. L., Heinzen, E. P., Hou, X., Al Hilli, M. M., Hurley, R. M., Wahner Hendrickson, A. E., Goergen, K. M., Larson, M. C., Becker, M. A., Eckel-Passow, J. E., Maurer, M. J., Kaufmann, S. H., Haluska, P. & Weroha, S. J., Dec 2021, In: Scientific reports. 11, 1, 8076.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

A microfluidic platform for cultivating ovarian cancer spheroids and testing their responses to chemotherapies

Dadgar, N., Gonzalez-Suarez, A. M., Fattahi, P., Hou, X., Weroha, J. S., Gaspar-Maia, A., Stybayeva, G. & Revzin, A., Dec 1 2020, In: Microsystems and Nanoengineering. 6, 1, 93.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

Harrington, B. S., He, Y., Khan, T., Puttick, S., Conroy, P. J., Kryza, T., Cuda, T., Sokolowski, K. A., Tse, B. W. C., Robbins, K. K., Arachchige, B. J., Stehbens, S. J., Pollock, P. M., Reed, S., Weroha, S. J., Haluska, P., Salomon, C., Lourie, R., Perrin, L. C., Law, R. H. P., & 2 othersWhisstock, J. C. & Hooper, J. D., 2020, In: Theranostics. 10, 5, p. 2095-2114 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinoma

Khan, T., He, Y., Kryza, T., Harrington, B. S., Gunter, J. H., Sullivan, M. A., Cuda, T., Rogers, R., Davies, C. M., Broomfield, A., Gough, M., Wu, A. C., McGann, T., Weroha, S. J., Haluska, P., Forbes, J. M., Armes, J. E., Barry, S. C., Coward, J. I., Jagasia, N., & 5 othersChetty, N., Snell, C. E., Lourie, R., Perrin, L. C. & Hooper, J. D., Apr 2020, In: Cancers. 12, 4, 869.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1

Hong, Z., Zhang, W., Ding, D., Huang, Z., Yan, Y., Cao, W., Pan, Y., Hou, X., Weroha, S. J., Karnes, R. J., Wang, D., Wu, Q., Wu, D. & Huang, H., Sep 17 2020, In: Molecular Cell. 79, 6, p. 1008-1023.e4

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Phase II trial of ribociclib and letrozole in patients with relapsed oestrogen receptor-positive ovarian or endometrial cancers

Colon-Otero, G., Zanfagnin, V., Hou, X., Foster, N. R., Asmus, E. J., Wahner Hendrickson, A., Jatoi, A., Block, M. S., Langstraat, C. L., Glaser, G. E., Dinh, T. A., Robertson, M. W., Camoriano, J. K., Butler, K. A., Copland, J. A. & John Weroha, S., Oct 27 2020, In: ESMO Open. 5, 5, e000926.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models

Santiago-O’Farrill, J. M., Weroha, S. J., Hou, X., Oberg, A. L., Heinzen, E. P., Maurer, M. J., Pang, L., Rask, P., Amaravadi, R. K., Becker, S. E., Romero, I., Rubio, M. J., Matias-Guiu, X., Santacana, M., Llombart-Cussac, A., Poveda, A., Lu, Z. & Bast, R. C., Feb 15 2020, In: Cancer. 126, 4, p. 894-907 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Role of adjuvant therapy in stage IIIC2 endometrial cancer

Bogani, G., Cappuccio, S., Casarin, J., Narasimhulu, D. M. M., Cilby, W. A., Glaser, G. E., Weaver, A. L., McGree, M. E., Keeney, G. L., Weroha, J., Petersen, I. A. & Mariani, A., Aug 1 2020, In: International Journal of Gynecological Cancer. 30, 8, p. 1169-1176 8 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Targeting an autocrine IL-6–SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma

Mehner, C., Miller, E., Hockla, A., Coban, M., Weroha, S. J., Radisky, D. C. & Radisky, E. S., Oct 15 2020, In: Oncogene. 39, 42, p. 6606-6618 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients

Block, M. S., Dietz, A. B., Gustafson, M. P., Kalli, K. R., Erskine, C. L., Youssef, B., Vijay, G. V., Allred, J. B., Pavelko, K. D., Strausbauch, M. A., Lin, Y., Grudem, M. E., Jatoi, A., Klampe, C. M., Wahner-Hendrickson, A. E., Weroha, S. J., Glaser, G. E., Kumar, A., Langstraat, C. L., Solseth, M. L., & 3 othersDeeds, M. C., Knutson, K. L. & Cannon, M. J., Dec 1 2020, In: Nature communications. 11, 1, 5173.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer

Serebrenik, A. A., Argyris, P. P., Jarvis, M. C., Brown, W. L., Bazzaro, M., Vogel, R. I., Erickson, B. K., Lee, S. H., Goergen, K. M., Maurer, M. J., Heinzen, E. P., Oberg, A. L., Huang, Y., Hou, X., John Weroha, S., Kaufmann, S. H. & Harris, R. S., Jul 2020, In: Clinical Cancer Research. 26, 13, p. 3397-3407 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2019

BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents

Kanakkanthara, A., Kurmi, K., Ekstrom, T. L., Hou, X., Purfeerst, E. R., Heinzen, E. P., Correia, C., Huntoon, C. J., O'Brien, D., Wahner Hendrickson, A. E., Dowdy, S. C., Li, H., Oberg, A. L., Hitosugi, T., Kaufmann, S. H., Weroha, S. J. & Karnitz, L. M., Dec 1 2019, In: Cancer research. 79, 23, p. 5920-5929 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Building a Research-Quality Copy Number Variation Data Repository for Translational Research

Wang, C., Moore, R. M., Evans, J. M., Hou, X., John Weroha, S. & Jiang, G., 2019, Heterogeneous Data Management, Polystores, and Analytics for Healthcare - VLDB 2018 Workshops, Poly and DMAH, 2018, Revised Selected Papers. Mattson, T., Wang, F., Teodoro, G., Stonebraker, M., Gadepally, V. & Luo, G. (eds.). Springer Verlag, p. 148-161 14 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11470 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis

Zhao, Y., Ding, L., Wang, D., Ye, Z., He, Y., Ma, L., Zhu, R., Pan, Y., Wu, Q., Pang, K., Hou, X., Weroha, S. J., Han, C., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L. & Huang, H., Mar 1 2019, In: EMBO Journal. 38, 5, e99599.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts

Liu, Y., Chanana, P., Davila, J. I., Hou, X., Zanfagnin, V., McGehee, C. D., Goode, E. L., Polley, E. C., Haluska, P., Weroha, S. J. & Wang, C., Dec 1 2019, In: Scientific reports. 9, 1, 6314.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Genes associated with bowel metastases in ovarian cancer

Mariani, A., Wang, C., Oberg, A. L., Riska, S. M., Torres, M., Kumka, J., Multinu, F., Sagar, G., Roy, D., Jung, DB. B., Zhang, Q., Grassi, T., Visscher, D. W., Patel, V. P., Jin, L., Staub, J. K., Cliby, W. A., Weroha, S. J., Kalli, K. R., Hartmann, L. C., & 3 othersKaufmann, S. H., Goode, E. L. & Shridhar, V., Sep 2019, In: Gynecologic oncology. 154, 3, p. 495-504 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A

Torres, D., Hou, X., Bale, L., Heinzen, E. P., Maurer, M. J., Zanfagnin, V., Oberg, A. L., Conover, C. & Weroha, S. J., Nov 1 2019, In: PloS one. 14, 11, e0224564.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer

Shuford, S., Wilhelm, C., Rayner, M., Elrod, A., Millard, M., Mattingly, C., Lotstein, A., Smith, A. M., Guo, Q. J., O’Donnell, L., Elder, J., Puls, L., Weroha, S. J., Hou, X., Zanfagnin, V., Nick, A., Stany, M. P., Maxwell, G. L., Conrads, T., Sood, A. K., & 5 othersOrr, D., Holmes, L. M., Gevaert, M., Crosswell, H. E. & DesRochers, T. M., Dec 1 2019, In: Scientific reports. 9, 1, 11153.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Saravut (John) Weroha, MD, PhD

Research output

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