Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2023
Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation
Ma, X., Iyer, S. R., Ma, X., Reginauld, S. H., Chen, Y., Pan, S., Zheng, Y., Moroni, D. G., Yu, Y., Zhang, L., Cannone, V., Chen, H. H., Ferrario, C. M., Sangaralingham, S. J. & Burnett, J. C., May 2023, In: International journal of molecular sciences. 24, 10, 8547.Research output: Contribution to journal › Article › peer-review
Open Access -
Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population
Ichiki, T., Cannone, V., Scott, C. G., Iyer, S. R., Sangaralingham, S. J., Bailey, K. R., Goetze, J. P., Tsuji, Y., Rodeheffer, R. J. & Burnett, J. C., Sep 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 3, p. H545-H552Research output: Contribution to journal › Article › peer-review
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2022
Natriuretic peptide pathways in heart failure: further therapeutic possibilities
Sangaralingham, S. J., Kuhn, M., Cannone, V., Chen, H. H. & Burnett, J. C., Dec 1 2022, In: Cardiovascular research. 118, 18, p. 3416-3433 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2021
A higher foci density of interstitial fibrosis and tubular atrophy predicts progressive CKD after a radical nephrectomy for tumor
Archila, L. R., Denic, A., Mullan, A. F., Narasimhan, R., Bogojevic, M., Thompson, R. H., Leibovich, B. C., Sangaralingham, S. J., Smith, M. L., Alexander, M. P. & Rule, A. D., Oct 2021, In: Journal of the American Society of Nephrology. 32, 10, p. 2623-2633 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
B-type natriuretic peptide and cardiac remodelling after myocardial infarction: A randomised trial
Hubers, S. A., Schirger, J. A., Sangaralingham, S. J., Chen, Y., Burnett, J. C., Hodge, D. & Chen, H. H., Mar 1 2021, In: Heart. 107, 5, p. 396-402 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators
Sangaralingham, S. J., Whig, K., Peddibhotla, S., Kirby, R. J., Sessions, H. E., Maloney, P. R., Hershberger, P. M., Mose-Yates, H., Hood, B. L., Vasile, S., Pan, S., Zheng, Y., Malany, S. & Burnett, J. C., Dec 28 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 52, e2109386118.Research output: Contribution to journal › Article › peer-review
Open Access -
First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension
Chen, H. H., Wan, S. H., Iyer, S. R., Cannone, V., Sangaralingham, S. J., Nuetel, J. & Burnett, J. C., Dec 1 2021, In: Hypertension. 78, 6, p. 1859-1867 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Prognostic Value of Urinary and Plasma C-Type Natriuretic Peptide in Acute Decompensated Heart Failure
Ma, X., Chen, Y., Reginauld, S. H., Scott, C. G., Iyer, S. R., Schaefer, J. J., Ichiki, T., Chen, H. H., Rule, A. D., Burnett, J. C. & Sangaralingham, S. J., Sep 2021, In: JACC: Heart Failure. 9, 9, p. 613-623 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature
Savira, F., Magaye, R., Liew, D., Reid, C., Kelly, D. J., Kompa, A. R., Sangaralingham, S. J., Burnett, J. C., Kaye, D. & Wang, B. H., Jul 1 2020, In: British Journal of Pharmacology. 177, 13, p. 2906-2922 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Comparative Effectiveness of Sacubitril-Valsartan Versus ACE/ARB Therapy in Heart Failure With Reduced Ejection Fraction
Tan, N. Y., Sangaralingham, L. R., Sangaralingham, S. J., Yao, X., Shah, N. D. & Dunlay, S. M., Jan 2020, In: JACC: Heart Failure. 8, 1, p. 43-54 12 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
C-type natriuretic peptide: The heart's guardian angel
Sangaralingham, S. J., Chen, Y. & Burnett, J. C., Mar 1 2020, In: European heart journal. 41, 9, p. 1021-1023 3 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Long-term blood pressure lowering and cGMP-activating actions of the novel ANP analog MANP
Chen, Y., Schaefer, J. J., Iyer, S. R., Harders, G. E., Pan, S., Sangaralingham, S. J., Chen, H. H., Redfield, M. M. & Burnett, J. C., Apr 2020, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 4, p. R669-R676Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2019
C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts
Chen, Y., Zheng, Y., Iyer, S. R., Harders, G. E., Pan, S., Chen, H. H., Ichiki, T., Burnett, J. C. & Sangaralingham, S. J., May 2019, In: Journal of Molecular and Cellular Cardiology. 130, p. 140-150 11 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Correction: Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor (Journal of Biological Chemistry (2019) 294 (12567–12578) DOI: 10.1074/jbc.RA119.008102)
Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Nov 29 2019, In: Journal of Biological Chemistry. 294, 48, p. 18516 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
CRRl269: A novel particulate guanylyl cyclase a receptor peptide activator for acute kidney injury
Chen, Y., Harty, G. J., Zheng, Y., Iyer, S. R., Sugihara, S., Sangaralingham, S. J., Ichiki, T., Grande, J. P., Lee, H. C., Wang, X. & Burnett, J. C., May 10 2019, In: Circulation research. 124, 10, p. 1462-1472 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Design, synthesis, and actions of an innovative bispecific designer peptide: NPA7
Meems, L. M. G., Andersen, I. A., Pan, S., Harty, G., Chen, Y., Zheng, Y., Harders, G. E., Ichiki, T., Heublein, D. M., Iyer, S. R., Sangaralingham, S. J., McCormick, D. J. & Burnett, J. C., Apr 1 2019, In: Hypertension. 73, 4, p. 900-909 10 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP
Reginauld, S. H., Cannone, V., Iyer, S., Scott, C., Bailey, K., Schaefer, J., Chen, Y., Sangaralingham, S. J. & Burnett, J. C., Oct 2019, In: JACC: Heart Failure. 7, 10, p. 891-898 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Aug 23 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
2018
Adoption of sacubitril/valsartan for the management of patients with heart failure
Sangaralingham, L. R., Sangaralingham, S. J., Shah, N. D., Yao, X. & Dunlay, S. M., Feb 1 2018, In: Circulation: Heart Failure. 11, 2, e004302.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure
Kawakami, R., Lee, C. Y. W., Scott, C., Bailey, K. R., Schirger, J. A., Chen, H. H., Benike, S. L., Cannone, V., Martin, F. L., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C., Sep 2018, In: Clinical pharmacology and therapeutics. 104, 3, p. 546-552 7 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population
Cannone, V., Buglioni, A., Sangaralingham, S. J., Scott, C., Bailey, K. R., Rodeheffer, R., Redfield, M. M., Sarzani, R. & Burnett, J. C., Aug 2018, In: Mayo Clinic proceedings. 93, 8, p. 980-990 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
CRRL269: A novel designer and renal-enhancing pGC-A peptide activator
Chen, Y., Harty, G. J., Huntley, B. K., Iyer, S. R., Heublein, D. M., Harders, G. E., Meems, L., Pan, S., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C., Mar 2018, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 314, 3, p. R407-R414Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Relaxing with c-type natriuretic peptide, the guanylyl cyclase b receptor, and pericytes
Sangaralingham, S. J. & Burnett, J. C., 2018, In: Circulation. 138, 5, p. 509-512 4 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
2017
Early activation of deleterious molecular pathways in the kidney in experimental heart failure with atrial remodeling
Ichiki, T., Huntley, B. K., Harty, G. J., Sangaralingham, S. J. & Burnett, J. C., May 2017, In: Physiological reports. 5, 9, e13283.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2016
Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen
Sangaralingham, S. J., Wang, B. H., Huang, L., Kumfu, S., Ichiki, T., Krum, H. & Burnett, J. C., Feb 1 2016, In: Peptides. 76, p. 108-114 7 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Cenderitide: Structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions
Lee, C. Y. W., Huntley, B. K., McCormick, D. J., Ichiki, T., Sangaralingham, S. J., Lisy, O. & Burnett, J. C., Apr 1 2016, In: European Heart Journal - Cardiovascular Pharmacotherapy. 2, 2, p. 98-105 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2015
Aldosterone predicts cardiovascular, renal, and metabolic disease in the general community: A 4-year follow-up
Buglioni, A., Cannone, V., Sangaralingham, S. J., Heublein, D. M., Scott, C. G., Bailey, K. R., Rodeheffer, R. J., Sarzani, R. & Burnett, J. C., Dec 1 2015, In: Journal of the American Heart Association. 4, 12, e002505.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Circulating aldosterone and natriuretic peptides in the general community relationship to cardiorenal and metabolic disease
Buglioni, A., Cannone, V., Cataliotti, A., Jeson Sangaralingham, S., Heublein, D. M., Scott, C. G., Bailey, K. R., Rodeheffer, R. J., Dessì-Fulgheri, P., Sarzani, R. & Burnett, J. C., Jan 20 2015, In: Hypertension. 65, 1, p. 45-53 9 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Circulating C-Type Natriuretic Peptide and Its Relationship to Cardiovascular Disease in the General Population
Sangaralingham, S. J., McKie, P. M., Ichiki, T., Scott, C. G., Heublein, D. M., Chen, H. H., Bailey, K. R., Redfield, M. M., Rodeheffer, R. J. & Burnett, J. C., Jun 20 2015, In: Hypertension. 65, 6, p. 1187-1194 8 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Pro-Atrial Natriuretic Peptide: A Novel Guanylyl Cyclase-A Receptor Activator That Goes Beyond Atrial and B-Type Natriuretic Peptides
Ichiki, T., Huntley, B. K., Sangaralingham, S. J. & Burnett, J. C., Sep 1 2015, In: JACC: Heart Failure. 3, 9, p. 715-723 9 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
ProB-type natriuretic peptide-1-108 processing and degradation in human heart failure
Huntley, B. K., Sandberg, S. M., Heublein, D. M., Jeson Sangaralingham, S., Burnett, J. C. & Ichiki, T., 2015, In: Circulation: Heart Failure. 8, 1, p. 89-97 9 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Urinary C-type natriuretic peptide: An emerging biomarker for heart failure and renal remodeling
Zakeri, R., Burnett, J. C. & Sangaralingham, S. J., Mar 1 2015, In: Clinica Chimica Acta. 443, p. 108-113 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
2014
Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: Regulation and therapeutic implications
Ichiki, T., Schirger, J. A., Huntley, B. K., Brozovich, F. V., Maleszewski, J. J., Sandberg, S. M., Sangaralingham, S. J., Park, S. J. & Burnett, J. C., Oct 1 2014, In: Journal of Molecular and Cellular Cardiology. 75, p. 199-205 7 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
McKie, P. M., Cataliotti, A., Ichiki, T., Sangaralingham, S. J., Chen, H. H. & Burnett, J. C., 2014, In: Journal of the American Heart Association. 3, 1, p. e000206Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2013
Differential expression of the pro-natriuretic peptide convertases corin and furin in experimental heart failure and atrial fibrosis
Ichiki, T., Boerrigter, G., Huntley, B. K., Jeson Sangaralingham, S., McKie, P. M., Harty, G. J., Harders, G. E. & Burnett, J. C., Jan 15 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 2, p. R102-R109Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Rationale and design of a randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy of B-type natriuretic peptide for the preservation of left ventricular function after anterior myocardial infarction
Sangaralingham, S. J., Burnett, J. C., McKie, P. M., Schirger, J. A. & Chen, H. H., Aug 2013, In: Journal of Cardiac Failure. 19, 8, p. 533-539 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Renin-angiotensin blockade combined with natriuretic peptide system augmentation novel therapeutic concepts to combat heart failure
Von Lueder, T. G., Sangaralingham, S. J., Wang, B. H., Kompa, A. R., Atar, D., Burnett, J. C. & Krum, H., May 2013, In: Circulation: Heart Failure. 6, 3, p. 594-605 12 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Urinary C-Type natriuretic peptide. A new heart failure biomarker
Zakeri, R., Sangaralingham, S. J., Sandberg, S. M., Heublein, D. M., Scott, C. G. & Burnett, J. C., Apr 2013, In: JACC: Heart Failure. 1, 2, p. 170-177 8 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
2012
Cardiac micro-computed tomography imaging of the aging coronary vasculature
Sangaralingham, S. J., Ritman, E. L., McKie, P. M., Ichiki, T., Lerman, A., Scott, C. G., Martin, F. L., Harders, G. E., Bellavia, D. & Burnett, J. C., 2012, In: Circulation: Cardiovascular Imaging. 5, 4, p. 518-524 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart
Martin, F. L., Sangaralingham, S. J., Huntley, B. K., McKie, P. M., Ichiki, T., Chen, H. H., Korinek, J., Harders, G. E. & Burnett, J. C., Dec 18 2012, In: PloS one. 7, 12, e52422.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: A kidney-heart connection
Martin, F. L., McKie, P. M., Cataliotti, A., Jeson Sangaralingham, S., Korinek, J., Huntley, B. K., Oehler, E. A., Harders, G. E., Ichiki, T., Mangiafico, S., Nath, K. A., Redfield, M. M., Chen, H. H. & Burnett, J. C., Jan 2012, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 302, 2, p. R292-R299Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
2011
Predictive utility of atrial, N-terminal pro-atrial, and N-terminal pro-B-type natriuretic peptides for mortality and cardiovascular events in the general community: A 9-year follow-up study
McKie, P. M., Cataliotti, A., Sangaralingham, S. J., Ichiki, T., Cannone, V., Bailey, K. R., Redfield, M. M., Rodeheffer, R. J. & Burnett, J. C., Dec 2011, In: Mayo Clinic proceedings. 86, 12, p. 1154-1160 7 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic peptide
Sangaralingham, S. J., Huntley, B. K., Martin, F. L., McKie, P. M., Bellavia, D., Ichiki, T., Harders, G. E., Chen, H. H. & Burnett, J. C., Feb 2011, In: Hypertension. 57, 2, p. 201-207 7 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
Urinary C-type natriuretic peptide excretion: A potential novel biomarker for renal fibrosis during aging
Jeson Sangaralingham, S., Heublein, D. M., Grande, J. P., Cataliotti, A., Rule, A. D., Mckie, P. M., Martin, F. L. & Burnett, J. C., Nov 2011, In: American Journal of Physiology - Renal Physiology. 301, 5, p. F943-F952Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2010
A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension
McKie, P. M., Cataliotti, A., Boerrigter, G., Chen, H. H., Sangaralingham, S. J., Martin, F. L., Ichiki, T. & Burnett, J. C., Dec 2010, In: Hypertension. 56, 6, p. 1152-1159 8 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts
Huntley, B. K., Ichiki, T., Sangaralingham, S. J., Chen, H. H. & Burnett, J. C., Oct 2010, In: Journal of Cellular Physiology. 225, 1, p. 251-255 5 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
CD-NP: An innovative designer natriuretic peptide activator of particulate guanylyl cyclase receptors for cardiorenal disease
McKie, P. M., Sangaralingham, S. J. & Burnett, J. C., Sep 2010, In: Current heart failure reports. 7, 3, p. 93-99 7 p.Research output: Contribution to journal › Review article › peer-review
32 Scopus citations -
2007
Estrogen delays the progression of salt-induced cardiac hypertrophy by influencing the renin-angiotensin system in heterozygous proANP gene-disrupted mice
Sangaralingham, S. J., Tse, M. Y. & Pang, S. C., Dec 2007, In: Molecular and Cellular Biochemistry. 306, 1-2, p. 221-230 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Estrogen protects against the development of salt-induced cardiac hypertophy in heterozygous proANP gene-disrupted mice
Sangaralingham, S. J., Yat Tse, M. & Pang, S. C., Jul 2007, In: Journal of Endocrinology. 194, 1, p. 143-152 10 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2003
Expression of the translational repressor NAT1 in experimental models of cardiac hypertrophy
Sangaralingham, S. J., Pak, B. J., Tse, M. Y., Angelis, E., Adams, M. A., Smallegange, C. & Pang, S. C., Mar 2003, In: Molecular and Cellular Biochemistry. 245, 1-2, p. 183-190 8 p.Research output: Contribution to journal › Review article › peer-review
8 Scopus citations