S Jeson Sangaralingham, MS, PhD

  • 699 Citations
  • 15 Scopus h-Index
19992019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1999 2019

  • 699 Citations
  • 15 Scopus h-Index
  • 35 Article
  • 2 Review article
  • 1 Editorial
2019
3 Citations (Scopus)
C-Type Natriuretic Peptide
Cyclic GMP
Fibroblasts
Kidney
Neprilysin
4 Citations (Scopus)

CRRL269

Chen, Y., Harty, G. J., Zheng, Y., Iyer, S. R., Sugihara, S., Sangaralingham, S. J., Ichiki, T., Grande, J. P., Lee, H. C., Wang, X. & Burnett, J. C. J., May 10 2019, In : Circulation research. 124, 10, p. 1462-1472 11 p.

Research output: Contribution to journalArticle

Open Access
Acute Kidney Injury
C-Type Natriuretic Peptide
Kidney
Apoptosis
Protective Agents
3 Citations (Scopus)

Design, Synthesis, and Actions of an Innovative Bispecific Designer Peptide

Meems, L. M. G., Andersen, I. A., Pan, S., Harty, G., Chen, Y., Zheng, Y., Harders, G. E., Ichiki, T., Heublein, D. M., Iyer, S. R., Sangaralingham, S. J., Mc Cormick, D. J. & Burnett, J. C. J., Apr 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 4, p. 900-909 10 p.

Research output: Contribution to journalArticle

Peptides
Cardiovascular Diseases
Therapeutics
Canidae
Ligands
2 Citations (Scopus)

Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP

Reginauld, S. H., Cannone, V., Iyer, S., Scott, C., Bailey, K., Schaefer, J., Chen, Y., Sangaralingham, S. J. & Burnett, J. C., Oct 2019, In : JACC: Heart Failure. 7, 10, p. 891-898 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
peptide B
Body Mass Index
2 Citations (Scopus)

Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C. J., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Jan 1 2019, In : Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.

Research output: Contribution to journalReview article

Open Access
Atrial Natriuretic Factor
Polysaccharides
Degradation
Glycosylation
Natriuretic Peptides
2018
10 Citations (Scopus)

Adoption of sacubitril/valsartan for the management of patients with heart failure

Sangaralingham, L. R., Sangaralingham, S. J., Shah, N. D., Yao, X. & Dunlay, S. M., Feb 1 2018, In : Circulation: Heart Failure. 11, 2, e004302.

Research output: Contribution to journalArticle

Heart Failure
United States Food and Drug Administration
Prescriptions
Drug Approval
Drug Costs
2 Citations (Scopus)

A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure

Kawakami, R., Lee, C. Y. W., Scott, C., Bailey, K. R., Schirger, J. A., Chen, H. H., Benike, S. L., Cannone, V., Martin, F. L., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C. J., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Cyclic GMP
Heart Failure
Safety
Natriuretic Peptides
C-Type Natriuretic Peptide
4 Citations (Scopus)

Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population

Cannone, V., Buglioni, A., Sangaralingham, S. J., Scott, C., Bailey, K. R., Rodeheffer, R., Redfield, M. M., Sarzani, R. & Burnett, J. C. J., Aug 1 2018, In : Mayo Clinic Proceedings. 93, 8, p. 980-990 11 p.

Research output: Contribution to journalArticle

Aldosterone
Antihypertensive Agents
Hypertension
Population
Atrial Natriuretic Factor
7 Citations (Scopus)

CRRL269: a novel designer and renal-enhancing pGC-A peptide activator

Chen, Y., Harty, G. J., Huntley, B. K., Iyer, S. R., Heublein, D. M., Harders, G. E., Meems, L., Pan, S., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C. J., Mar 1 2018, In : American journal of physiology. Regulatory, integrative and comparative physiology. 314, 3, p. R407-R414

Research output: Contribution to journalArticle

Kidney
Peptides
Canidae
Natriuretic Peptides
Renin-Angiotensin System
1 Citation (Scopus)

Relaxing With C-Type Natriuretic Peptide, the Guanylyl Cyclase B Receptor, and Pericytes

Sangaralingham, S. J. & Burnett, J. C. J., Jul 31 2018, In : Circulation. 138, 5, p. 509-512 4 p.

Research output: Contribution to journalEditorial

Guanylate Cyclase-Coupled Receptors
C-Type Natriuretic Peptide
Pericytes
Natriuretic Peptides
Hypertension
2017
3 Citations (Scopus)

Early activation of deleterious molecular pathways in the kidney in experimental heart failure with atrial remodeling

Ichiki, T., Huntley, B. K., Harty, G. J., Sangaralingham, S. J. & Burnett, J. C. J., May 1 2017, In : Physiological Reports. 5, 9, e13283.

Research output: Contribution to journalArticle

Atrial Remodeling
Heart Failure
Kidney
Kidney Cortex
Genes
2016
20 Citations (Scopus)

Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen

Sangaralingham, S. J., Wang, B. H., Huang, L., Kumfu, S., Ichiki, T., Krum, H. & Burnett, J. C. J., Feb 1 2016, In : Peptides. 76, p. 108-114 7 p.

Research output: Contribution to journalArticle

Aldosterone
Natriuretic Peptides
Angiotensins
Fibrosis
Collagen
14 Citations (Scopus)
Guanylate Cyclase-Coupled Receptors
C-Type Natriuretic Peptide
Kidney
Cyclic GMP
Guanylate Cyclase
2015
11 Citations (Scopus)

Aldosterone predicts cardiovascular, renal, and metabolic disease in the general community: A 4-year follow-up

Buglioni, A., Cannone, V., Sangaralingham, S. J., Heublein, D. M., Scott, C. G., Bailey, K. R., Rodeheffer, R. J., Sarzani, R. & Burnett, J. C. J., Dec 1 2015, In : Journal of the American Heart Association. 4, 12, e002505.

Research output: Contribution to journalArticle

Metabolic Diseases
Aldosterone
Cardiovascular Diseases
Kidney
Hypertension
44 Citations (Scopus)

Circulating aldosterone and natriuretic peptides in the general community relationship to cardiorenal and metabolic disease

Buglioni, A., Cannone, V., Cataliotti, A., Sangaralingham, S. J., Heublein, D. M., Scott, C. G., Bailey, K. R., Rodeheffer, R. J., Dessì-Fulgheri, P., Sarzani, R. & Burnett, J. C. J., Jan 20 2015, In : Hypertension. 65, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Metabolic Diseases
Aldosterone
Odds Ratio
Confidence Intervals
18 Citations (Scopus)

Circulating C-Type Natriuretic Peptide and Its Relationship to Cardiovascular Disease in the General Population

Sangaralingham, S. J., McKie, P., Ichiki, T., Scott, C. G., Heublein, D. M., Chen, H. H., Bailey, K. R., Redfield, M. M., Rodeheffer, R. J. & Burnett, J. C. J., Jun 20 2015, In : Hypertension. 65, 6, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Cardiovascular Diseases
Population
Myocardial Infarction
Phenotype
15 Citations (Scopus)
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Cyclic GMP
Kidney
Heart Failure
27 Citations (Scopus)

ProB-type natriuretic peptide-1-108 processing and degradation in human heart failure

Huntley, B. K., Sandberg, S. M., Heublein, D. M., Sangaralingham, S. J., Burnett, J. C. J. & Ichiki, T., 2015, In : Circulation: Heart Failure. 8, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Heart Failure
Serum
Pro-BNP1-108
Dipeptidyl Peptidase 4
14 Citations (Scopus)

Urinary C-type natriuretic peptide: An emerging biomarker for heart failure and renal remodeling

Zakeri, R., Burnett, J. C. J. & Sangaralingham, S. J., Mar 1 2015, In : Clinica Chimica Acta. 443, p. 108-113 6 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Biomarkers
Heart Failure
Kidney
Cardio-Renal Syndrome
2014
26 Citations (Scopus)

Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: Regulation and therapeutic implications

Ichiki, T., Schirger, J. A., Huntley, B. K., Brozovich, F. V., Maleszewski, J., Sandberg, S. M., Sangaralingham, S. J., Park, S. J. & Burnett, J. C. J., Oct 1 2014, In : Journal of Molecular and Cellular Cardiology. 75, p. 199-205 7 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Guanylate Cyclase
Heart-Assist Devices
Fibrosis
Heart Failure
14 Citations (Scopus)
Nitroglycerin
Atrial Natriuretic Factor
Canidae
Theoretical Models
Heart Failure
2013
26 Citations (Scopus)
Furin
Natriuretic Peptides
Fibrosis
Heart Failure
Heart Atria
9 Citations (Scopus)
Brain Natriuretic Peptide
Controlled Clinical Trials
Left Ventricular Function
Myocardial Infarction
Placebos
85 Citations (Scopus)

Renin-angiotensin blockade combined with natriuretic peptide system augmentation novel therapeutic concepts to combat heart failure

Von Lueder, T. G., Sangaralingham, S. J., Wang, B. H., Kompa, A. R., Atar, D., Burnett, J. C. J. & Krum, H., May 2013, In : Circulation: Heart Failure. 6, 3, p. 594-605 12 p.

Research output: Contribution to journalArticle

Tetrazoles
Designer Drugs
C-Type Natriuretic Peptide
Aminobutyrates
Neprilysin
21 Citations (Scopus)

Urinary C-Type natriuretic peptide. A new heart failure biomarker

Zakeri, R., Sangaralingham, S. J., Sandberg, S. M., Heublein, D. M., Scott, C. G. & Burnett, J. C. J., Apr 2013, In : JACC: Heart Failure. 1, 2, p. 170-177 8 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Heart Failure
Biomarkers
Brain Natriuretic Peptide
Kidney
2012
15 Citations (Scopus)

Cardiac micro-computed tomography imaging of the aging coronary vasculature

Sangaralingham, S. J., Ritman, E. L., McKie, P., Ichiki, T., Lerman, A., Scott, C. G., Martin, F. L., Harders, G. E., Bellavia, D. & Burnett, J. C. J., 2012, In : Circulation: Cardiovascular Imaging. 5, 4, p. 518-524 7 p.

Research output: Contribution to journalArticle

Tomography
Fibrosis
Coronary Circulation
Left Ventricular Dysfunction
Left Ventricular Function
38 Citations (Scopus)

CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart

Martin, F. L., Sangaralingham, S. J., Huntley, B. K., McKie, P., Ichiki, T., Chen, H. H., Korinek, J., Harders, G. E. & Burnett, J. C. J., Dec 18 2012, In : PLoS One. 7, 12, e52422.

Research output: Contribution to journalArticle

natriuretic peptides
guanylate cyclase
Natriuretic Peptides
Guanylate Cyclase
heart
48 Citations (Scopus)

Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: A kidney-heart connection

Martin, F. L., McKie, P., Cataliotti, A., Sangaralingham, S. J., Korinek, J., Huntley, B. K., Oehler, E. A., Harders, G. E., Ichiki, T., Mangiafico, S., Nath, K. A., Redfield, M. M., Chen, H. H. & Burnett, J. C. J., Jan 2012, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 302, 2

Research output: Contribution to journalArticle

Renal Insufficiency
Fibrosis
Apoptosis
Kidney
Brain Natriuretic Peptide
2011
43 Citations (Scopus)
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
Mortality
Myocardial Infarction
58 Citations (Scopus)

The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic peptide

Sangaralingham, S. J., Huntley, B. K., Martin, F. L., McKie, P., Bellavia, D., Ichiki, T., Harders, G. E., Chen, H. H. & Burnett, J. C. J., Feb 2011, In : Hypertension. 57, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Fibrosis
Left Ventricular Function
Fibroblasts
Inbred F344 Rats
23 Citations (Scopus)
C-Type Natriuretic Peptide
Fibrosis
Biomarkers
Kidney
Glomerular Basement Membrane
2010
20 Citations (Scopus)

A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension

McKie, P., Cataliotti, A., Boerrigter, G., Chen, H. H., Sangaralingham, S. J., Martin, F. L., Ichiki, T. & Burnett, J. C. J., Dec 2010, In : Hypertension. 56, 6, p. 1152-1159 8 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Angiotensin II
Hypertension
Therapeutics
Natriuretic Peptides
13 Citations (Scopus)

B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts

Huntley, B. K., Ichiki, T., Sangaralingham, S. J., Chen, H. H. & Burnett, J. C. J., Oct 2010, In : Journal of Cellular Physiology. 225, 1, p. 251-255 5 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
Brain Natriuretic Peptide
Cyclic GMP
Fibroblasts
Fibronectins
32 Citations (Scopus)
Guanylate Cyclase-Coupled Receptors
Natriuretic Peptides
C-Type Natriuretic Peptide
Brain Natriuretic Peptide
Pressure effects
2007
3 Citations (Scopus)
Angiotensins
Cardiomegaly
Atrial Natriuretic Factor
Renin-Angiotensin System
Renin
8 Citations (Scopus)

Estrogen protects against the development of salt-induced cardiac hypertophy in heterozygous proANP gene-disrupted mice

Sangaralingham, S. J., Yat Tse, M. & Pang, S. C., Jul 2007, In : Journal of Endocrinology. 194, 1, p. 143-152 10 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Estrogens
Salts
Cardiomegaly
Natriuretic Peptides
2003
8 Citations (Scopus)

Expression of the translational repressor NAT1 in experimental models of cardiac hypertrophy

Sangaralingham, S. J., Pak, B. J., Tse, M. Y., Angelis, E., Adams, M. A., Smallegange, C. & Pang, S. C., Mar 2003, In : Molecular and Cellular Biochemistry. 245, 1-2, p. 183-190 8 p.

Research output: Contribution to journalReview article

Cardiomegaly
Rats
Theoretical Models
Cardiovascular system
Messenger RNA
1999
5 Citations (Scopus)

Molecular cloning and developmental expression of rat glycogenin in cardiac tissue

Pak, B. J., Sangaralingham, S. J. & Pang, S. C., 1999, In : Molecular and Cellular Biochemistry. 194, 1-2, p. 117-123 7 p.

Research output: Contribution to journalArticle

Cloning
Molecular Cloning
Rats
Tissue
Glycogen