• 116971 Citations
  • 152 Scopus h-Index
1974 …2020
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Research Output 1974 2020

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Article
2015
50 Citations (Scopus)

Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease

Carrasquillo, M. M., Crook, J., Pedraza, O. D., Thomas, C. S., Pankratz, V. S., Allen, M., Nguyen, T., Malphrus, K. G., Ma, L., Bisceglio, G. D., Roberts, R. O., Lucas, J. A., Smith, G. E., Ivnik, R. J., Machulda, M. M., Graff Radford, N. R., Petersen, R. C., Younkin, S. G. & Taner, N., Jan 1 2015, In : Neurobiology of Aging. 36, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome-Wide Association Study
Cognitive Dysfunction
9 Citations (Scopus)

Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials

Donohue, M. C., Moghadam, S. H., Roe, A. D., Sun, C. K., Edland, S. D., Thomas, R. G., Petersen, R. C., Sano, M., Galasko, D., Aisen, P. S. & Rissman, R. A., Sep 1 2015, In : Alzheimer's and Dementia. 11, 9, p. 1069-1079 11 p., 1909.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Clinical Trials
Simvastatin
Apolipoprotein E4
65 Citations (Scopus)

Low neural exosomal levels of cellular survival factors in Alzheimer's disease

Goetzl, E. J., Boxer, A., Schwartz, J. B., Abner, E. L., Petersen, R. C., Miller, B. L., Carlson, O. D., Mustapic, M. & Kapogiannis, D., Jul 1 2015, In : Annals of Clinical and Translational Neurology. 2, 7, p. 769-773 5 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Transcription Factors
Transcriptional Silencer Elements
Survival
Frontotemporal Dementia
11 Citations (Scopus)

Microbleeds in atypical presentations of Alzheimer's disease: A comparison to dementia of the Alzheimer's type

Whitwell, J. L., Kantarci, K. M., Weigand, S. D., Lundt, E. S., Gunter, J. L., Duffy, J. R., Strand, E. A., Machulda, M. M., Spychalla, A. J., Drubach, D., Petersen, R. C., Lowe, V., Jack, C. R. J. & Josephs, K. A., 2015, In : Journal of Alzheimer's Disease. 45, 4, p. 1109-1117 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Frontal Lobe
Language
Amyloid
Cognition
17 Citations (Scopus)

Mild Neurocognitive disorder: An old wine in a new bottle

Stokin, G. B., Krell-Roesch, J., Petersen, R. C. & Geda, Y. E., Sep 19 2015, In : Harvard Review of Psychiatry. 23, 5, p. 368-376 9 p.

Research output: Contribution to journalArticle

Wine
Diagnostic and Statistical Manual of Mental Disorders
Cognitive Dysfunction
Delirium
Mental Disorders
27 Citations (Scopus)

Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders

Ogaki, K., Koga, S., Heckman, M. G., Fiesel, F., Ando, M., Labbé, C., Lorenzo-Betancor, O., Moussaud-Lamodière, E. L., Soto-Ortolaza, A. I., Walton, R. L., Strongosky, A. J., Uitti, R. J., McCarthy, A., Lynch, T., Siuda, J., Opala, G., Rudzinska, M., Krygowska-Wajs, A., Barcikowska, M., Czyzewski, K. & 12 others, Puschmann, A., Nishioka, K., Funayama, M., Hattori, N., Parisi, J. E., Petersen, R. C., Graff Radford, N. R., Boeve, B. F., Springer, W., Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Dec 8 2015, In : Neurology. 85, 23, p. 2016-2025 10 p.

Research output: Contribution to journalArticle

Lewy Bodies
Lewy Body Disease
Parkinson Disease
Genes
Exons
18 Citations (Scopus)
Sex Factors
Life Style
Mortality
Heart Diseases
Exercise
11 Citations (Scopus)

MRS in Mild Cognitive Impairment: Early Differentiation of Dementia with Lewy Bodies and Alzheimer's Disease

Zhang, B., Ferman, T. J., Boeve, B. F., Smith, G. E., Maroney-Smith, M., Spychalla, A. J., Knopman, D. S., Jack, C. R. J., Petersen, R. C. & Kantarci, K. M., Mar 1 2015, In : Journal of Neuroimaging. 25, 2, p. 269-274 6 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Dementia
Alzheimer Disease
Magnetic Resonance Spectroscopy
Gyrus Cinguli
38 Citations (Scopus)

Multimorbidity and risk of mild cognitive impairment

Vassilaki, M., Aakre, J. A., Cha, R. H., Kremers, W. K., St. Sauver, J., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Petersen, R. C. & Roberts, R. O., Sep 1 2015, In : Journal of the American Geriatrics Society. 63, 9, p. 1783-1790 8 p.

Research output: Contribution to journalArticle

Dementia
Comorbidity
Confidence Intervals
Medical Record Linkage
International Classification of Diseases
39 Citations (Scopus)

Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: A population-based study

Pink, A., Stokin, G. B., Bartley, M. M., Roberts, R. O., Sochor, O., Machulda, M. M., Krell-Roesch, J., Knopman, D. S., Acosta, J. I., Christianson, T. J., Pankratz, V. S., Mielke, M. M., Petersen, R. C. & Geda, Y. E., Mar 3 2015, In : Neurology. 84, 9, p. 935-943 9 p.

Research output: Contribution to journalArticle

Dementia
Apathy
Depression
Population
Confidence Intervals
8 Citations (Scopus)

New criteria for Alzheimer's disease: Which, when and why?

Schott, J. M. & Petersen, R. C., May 1 2015, In : Brain. 138, 5, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

Alzheimer's Disease
Mild Cognitive Impairment
44 Citations (Scopus)

Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72

Van Blitterswijk, M., Gendron, T. D., Baker, M. C., DeJesus-Hernandez, M., Finch, N. C. A., Brown, P. H., Daughrity, L. M., Murray, M. E., Heckman, M. G., Jiang, J., Lagier-Tourenne, C., Edbauer, D., Cleveland, D. W., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Petrucelli, L., Boeve, B. F., Graff Radford, N. R. & 3 others, Boylan, K. B., Dickson, D. W. & Rademakers, R. V., Dec 1 2015, In : Acta Neuropathologica. 130, 6, p. 863-876 14 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Introns
Open Reading Frames
Cerebellum
Frontal Lobe
65 Citations (Scopus)

Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies

Nedelska, Z., Ferman, T. J., Boeve, B. F., Przybelski, S. A., Lesnick, T. G., Murray, M. E., Gunter, J. L., Senjem, M. L., Vemuri, P. D., Smith, G. E., Geda, Y. E., Graff-Radford, J., Knopman, D. S., Petersen, R. C., Parisi, J. E., Dickson, D. W., Jack, C. R. J. & Kantarci, K. M., Jan 1 2015, In : Neurobiology of Aging. 36, 1, p. 452-461 10 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Atrophy
Autopsy
Alzheimer Disease
Brain
18 Citations (Scopus)

Performance of the CogState computerized battery in the Mayo Clinic Study on Aging

Mielke, M. M., Machulda, M. M., Hagen, C. E., Edwards, K. K., Roberts, R. O., Pankratz, V. S., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., Nov 1 2015, In : Alzheimer's and Dementia. 11, 11, p. 1367-1376 10 p.

Research output: Contribution to journalArticle

Microcomputers
Neuropsychological Tests
Population
Learning
37 Citations (Scopus)

Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging

Pankratz, V. S., Roberts, R. O., Mielke, M. M., Knopman, D. S., Jack, C. R. J., Geda, Y. E., Rocca, W. A. & Petersen, R. C., Apr 7 2015, In : Neurology. 84, 14, p. 1433-1442 10 p.

Research output: Contribution to journalArticle

Demography
Aptitude
Cognitive Dysfunction
Proportional Hazards Models
Population
33 Citations (Scopus)

Protective variant for hippocampal atrophy identified by whole exome sequencing

Nho, K., Kim, S., Risacher, S. L., Shen, L., Corneveaux, J. J., Swaminathan, S., Lin, H., Ramanan, V. K., Liu, Y., Foroud, T. M., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R. J., Weiner, M. W., Baldwin, C. T., Lunetta, K. L. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Mar 1 2015, In : Annals of Neurology. 77, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

Exome
Neurogenesis
Neuroimaging
Computer Simulation
Atrophy
20 Citations (Scopus)

Rarity of the alzheimer disease-protective APP A673T variant in the United States

National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, Feb 1 2015, In : JAMA Neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Genes
Sweden
Alanine
31 Citations (Scopus)

Risk and protective factors for cognitive impairment in persons aged 85 years and older

Roberts, R. O., Cha, R. H., Mielke, M. M., Geda, Y. E., Boeve, B. F., Machulda, M. M., Knopman, D. S. & Petersen, R. C., May 5 2015, In : Neurology. 84, 18, p. 1854-1861 8 p.

Research output: Contribution to journalArticle

Life Style
Sex Education
Protective Factors
Cognitive Dysfunction
Vascular Diseases
18 Citations (Scopus)

Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies

Labbé, C., Ogaki, K., Lorenzo-Betancor, O., Soto-Ortolaza, A. I., Walton, R. L., Rayaprolu, S., Fujioka, S., Murray, M. E., Heckman, M. G., Puschmann, A., McCarthy, A., Lynch, T., Siuda, J., Opala, G., Rudzinska, M., Krygowska-Wajs, A., Barcikowska, M., Czyzewski, K., Sanotsky, Y., Rektorová, I. & 16 others, McLean, P. J., Rademakers, R. V., Taner, N., Hassan, A., Ahlskog, J. E., Boeve, B. F., Petersen, R. C., Maraganore, D. M., Adler, C. H., Ferman, T. J., Parisi, J. E., Graff Radford, N. R., Uitti, R. J., Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Nov 10 2015, In : Neurology. 85, 19, p. 1680-1686 7 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Microtubule-Associated Proteins
Gene Frequency
Odds Ratio
Confidence Intervals
13 Citations (Scopus)

Role of β-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment

Knopman, D. S., Jack, C. R. J., Lundt, E. S., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Dec 1 2015, In : JAMA Neurology. 72, 12, p. 1475-1483 9 p.

Research output: Contribution to journalArticle

Amyloidosis
Alzheimer Disease
Positron-Emission Tomography
Parietal Lobe
Neuroimaging
2 Citations (Scopus)

Sample size calculations for clinical trials targeting tauopathies: a new potential disease target

Whitwell, J. L., Duffy, J. R., Strand, E. A., Machulda, M. M., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Spychalla, A. J., Gunter, J. L., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., Sep 22 2015, In : Journal of Neurology. 262, 9, p. 2064-2072 9 p.

Research output: Contribution to journalArticle

Tauopathies
Apraxias
Sample Size
Clinical Trials
Atrophy
34 Citations (Scopus)

Self-rated and informant-rated everyday function in comparison to objective markers of Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative, Sep 1 2015, In : Alzheimer's and Dementia. 11, 9, p. 1080-1089 10 p., 1918.

Research output: Contribution to journalArticle

Alzheimer Disease
Aptitude
Amyloid
Positron-Emission Tomography
Self Report
31 Citations (Scopus)

Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging

Knopman, D. S., Beiser, A., Machulda, M. M., Fields, J. A., Roberts, R. O., Pankratz, V. S., Aakre, J., Cha, R. H., Rocca, W. A., Mielke, M. M., Boeve, B. F., Devine, S., Ivnik, R. J., Au, R., Auerbach, S., Wolf, P. A., Seshadri, S. & Petersen, R. C., Nov 10 2015, In : Neurology. 85, 19, p. 1712-1721 10 p.

Research output: Contribution to journalArticle

Cognition
Dementia
Neuropsychological Tests
Consensus
Population
131 Citations (Scopus)

Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies

Rabin, L. A., Smart, C. M., Crane, P. K., Amariglio, R. E., Berman, L. M., Boada, M., Buckley, R. F., Chételat, G., Dubois, B., Ellis, K. A., Gifford, K. A., Jefferson, A. L., Jessen, F., Katz, M. J., Lipton, R. B., Luck, T., Maruff, P., Mielke, M. M., Molinuevo, J. L., Naeem, F. & 18 others, Perrotin, A., Petersen, R. C., Rami, L., Reisberg, B., Rentz, D. M., Riedel-Heller, S. G., Risacher, S. L., Rodriguez, O., Sachdev, P. S., Saykin, A. J., Slavin, M. J., Snitz, B. E., Sperling, R. A., Tandetnik, C., Van Der Flier, W. M., Wagner, M., Wolfsgruber, S. & Sikkes, S. A. M., Sep 24 2015, In : Journal of Alzheimer's Disease. 48, S1, p. S63-S86

Research output: Contribution to journalArticle

Self Report
Research
Cognitive Dysfunction
Executive Function
Names
2 Citations (Scopus)

Subjective cognitive impairment et maladie d'Alzheimer: Étude d'une cohorte de 51 sujets suivis sur deux ans

Translated title of the contribution: Subjective cognitive impairment and Alzheimer's disease: A two year follow up of 51 subjects during two yearsSambuchi, N., Muraccioli, I., Alescio-Lautier, BÉ., Paban, VÉ., Sambuc, R., Jouve, É., Geda, Y. E., Petersen, R. C. & Michel, B. F., Dec 1 2015, In : Geriatrie et Psychologie Neuropsychiatrie du Vieillissement. 13, 4, p. 462-471 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Cognitive Dysfunction
Atrophy
Episodic Memory
Executive Function
32 Citations (Scopus)

TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

Josephs, K. A., Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Murray, M. E., Liesinger, A. M., Petrucelli, L., Senjem, M. L., Ivnik, R. J., Parisi, J. E., Petersen, R. C. & Dickson, D. W., Nov 1 2015, In : Annals of Neurology. 78, 5, p. 697-709 13 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Alzheimer Disease
Pathology
Neurofibrillary Tangles
Memory Disorders
30 Citations (Scopus)

The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans

Kang, J. H., Korecka, M., Figurski, M. J., Toledo, J. B., Blennow, K., Zetterberg, H., Waligorska, T., Brylska, M., Fields, L., Shah, N., Soares, H., Dean, R. A., Vanderstichele, H., Petersen, R. C., Aisen, P. S., Saykin, A. J., Weiner, M. W., Trojanowski, J. Q. & Shaw, L. M., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 772-791 20 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Biomarkers
Cerebrospinal Fluid
Prodromal Symptoms
5 Citations (Scopus)

The human Alzheimer disease project: A new call to arms

Rosenberg, R. N. & Petersen, R. C., Jun 1 2015, In : JAMA Neurology. 72, 6, p. 626-628 3 p.

Research output: Contribution to journalArticle

Alzheimer Disease
63 Citations (Scopus)
Amyloid
Longitudinal Studies
Dementia
Cohort Studies
Biomarkers
112 Citations (Scopus)

Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Preboske, G. M., Kantarci, K. M., Raman, M. R., Machulda, M. M., Mielke, M. M., Lowe, V., Senjem, M. L., Gunter, J. L., Rocca, W. A., Roberts, R. O., Petersen, R. C. & Jack, C. R. J., Mar 1 2015, In : Brain : a journal of neurology. 138, p. 761-771 11 p.

Research output: Contribution to journalArticle

Amyloid
Blood Vessels
Pathology
Cognitive Reserve
Positron-Emission Tomography
17 Citations (Scopus)

White matter integrity in dementia with Lewy bodies: A voxel-based analysis of diffusion tensor imaging

Nedelska, Z., Schwarz, C., Boeve, B. F., Lowe, V., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Gunter, J. L., Senjem, M. L., Ferman, T. J., Smith, G. E., Geda, Y. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Jun 1 2015, In : Neurobiology of Aging. 36, 6, p. 2010-2017 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Diffusion Tensor Imaging
Alzheimer Disease
Glucose
Amyloid
140 Citations (Scopus)

Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease

Pottier, C., Bieniek, K. F., Finch, N. C., van de Vorst, M., Baker, M., Perkersen, R., Brown, P., Ravenscroft, T., Van Blitterswijk, M., Nicholson, A. M., Deture, M., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Boylan, K. B., Boeve, B. F., Graff Radford, N. R., Veltman, J. A., Gilissen, C. & 3 others, Murray, M. E., Dickson, D. W. & Rademakers, R. V., May 6 2015, In : Acta Neuropathologica. 130, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Motor Neuron Disease
DNA-Binding Proteins
Phosphotransferases
Genome
38 Citations (Scopus)

Working memory and language network dysfunctions in logopenic aphasia: A task-free fMRI comparison with Alzheimer's dementia

Whitwell, J. L., Jones, D. T., Duffy, J. R., Strand, E. A., Machulda, M. M., Przybelski, S. A., Vemuri, P. D., Gregg, B. E., Gunter, J. L., Senjem, M. L., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., Mar 1 2015, In : Neurobiology of Aging. 36, 3, p. 1245-1252 8 p.

Research output: Contribution to journalArticle

Aphasia
Short-Term Memory
Alzheimer Disease
Language
Magnetic Resonance Imaging
2014
60 Citations (Scopus)

18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Lundt, E. S., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Roberts, R. O., Boeve, B. F. & Petersen, R. C., 2014, In : Neurobiology of Aging. 35, 9, p. 2096-2106 11 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Fluorodeoxyglucose F18
Apolipoproteins E
Positron-Emission Tomography
Genotype
42 Citations (Scopus)

2014 Report on the milestones for the us national plan to address Alzheimer's disease

Fargo, K. N., Aisen, P., Albert, M., Au, R., Corrada, M. M., Dekosky, S., Drachman, D., Fillit, H., Gitlin, L., Haas, M., Herrup, K., Kawas, C., Khachaturian, A. S., Khachaturian, Z. S., Klunk, W., Knopman, D. S., Kukull, W. A., Lamb, B., Logsdon, R. G., Maruff, P. & 20 others, Mesulam, M., Mobley, W., Mohs, R., Morgan, D., Nixon, R. A., Paul, S., Petersen, R. C., Plassman, B., Potter, W., Reiman, E., Reisberg, B., Sano, M., Schindler, R., Schneider, L. S., Snyder, P. J., Sperling, R. A., Yaffe, K., Bain, L. J., Thies, W. H. & Carrillo, M. C., Oct 1 2014, In : Alzheimer's and Dementia. 10, 5, p. S430-S452

Research output: Contribution to journalArticle

Alzheimer Disease
Health Services
United States Dept. of Health and Human Services
Research
Developed Countries
25 Citations (Scopus)

Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test

Ferman, T. J., Smith, G. E., Dickson, D. W., Graff Radford, N. R., Lin, S. C., Wszolek, Z. K., Van Gerpen, J. A., Uitti, R., Knopman, D. S., Petersen, R. C., Parisi, J. E., Silber, M. H. & Boeve, B. F., 2014, In : Alzheimer's Research and Therapy. 6, 6, 76.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Sleep
Dementia
Brain Stem
605 Citations (Scopus)

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

Jessen, F., Amariglio, R. E., Van Boxtel, M., Breteler, M., Ceccaldi, M., Chételat, G., Dubois, B., Dufouil, C., Ellis, K. A., Van Der Flier, W. M., Glodzik, L., Van Harten, A. C., De Leon, M. J., McHugh, P., Mielke, M. M., Molinuevo, J. L., Mosconi, L., Osorio, R. S., Perrotin, A., Petersen, R. C. & 16 others, Rabin, L. A., Rami, L., Reisberg, B., Rentz, D. M., Sachdev, P. S., De La Sayette, V., Saykin, A. J., Scheltens, P., Shulman, M. B., Slavin, M. J., Sperling, R. A., Stewart, R., Uspenskaya, O., Vellas, B., Visser, P. J. & Wagner, M., Nov 1 2014, In : Alzheimer's and Dementia. 10, 6, p. 844-852 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Research
Cognitive Dysfunction
Terminology
Consensus
188 Citations (Scopus)

Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: A cross-sectional study

Jack, C. R. J., Wiste, H. J., Weigand, S. D., Rocca, W. A., Knopman, D. S., Mielke, M. M., Lowe, V., Senjem, M. L., Gunter, J. L., Preboske, G. M., Pankratz, V. S., Vemuri, P. D. & Petersen, R. C., Oct 1 2014, In : The Lancet Neurology. 13, 10, p. 997-1005 9 p.

Research output: Contribution to journalArticle

Amyloid
Cognition
Cross-Sectional Studies
Alzheimer Disease
Population
31 Citations (Scopus)

Antemortem MRI findings associated with microinfarcts at autopsy

Raman, M. R., Preboske, G. M., Przybelski, S. A., Gunter, J. L., Senjem, M. L., Vemuri, P. D., Murphy, M., Murray, M. E., Boeve, B. F., Knopman, D. S., Petersen, R. C., Parisi, J. E., Dickson, D. W., Jack, C. R. J. & Kantarci, K. M., Jun 3 2014, In : Neurology. 82, 22, p. 1951-1958 8 p.

Research output: Contribution to journalArticle

Autopsy
Atrophy
Brain
Alzheimer Disease
Research Design
105 Citations (Scopus)

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T. M., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R. J., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A. J., Mar 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Genome-Wide Association Study
Apolipoproteins E
Amyloid
Positron-Emission Tomography
18 Citations (Scopus)

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

Medway, C. W., Abdul-Hay, S., Mims, T., Ma, L., Bisceglio, G., Zou, F., Pankratz, S., Sando, S. B., Aasly, J. O., Barcikowska, M., Siuda, J., Wszolek, Z. K., Ross, O. A., Carrasquillo, M. M., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Taner, N., Morgan, K., Bu, G. D. & 1 others, Younkin, S. G., Mar 10 2014, In : Molecular Neurodegeneration. 9, 1, 11.

Research output: Contribution to journalArticle

Apolipoproteins E
Alzheimer Disease
Exome
Alleles
Linkage Disequilibrium
61 Citations (Scopus)

A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment

Singh, B., Mielke, M. M., Parsaik, A. K., Cha, R. H., Roberts, R. O., Scanlon, P. D., Geda, Y. E., Christianson, T. J., Pankratz, V. S. & Petersen, R. C., 2014, In : JAMA Neurology. 71, 5, p. 581-588 8 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Prospective Studies
Cognitive Dysfunction
Mild Cognitive Impairment
Medical Record Linkage
65 Citations (Scopus)

Association of diabetes with amnestic and nonamnestic mild cognitive impairment

Roberts, R. O., Knopman, D. S., Geda, Y. E., Cha, R. H., Pankratz, V. S., Baertlein, L., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Mielke, M. M. & Petersen, R. C., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Cognitive Dysfunction
Dementia
Alzheimer Disease
Vascular Diseases
48 Citations (Scopus)

Association of hypometabolism and amyloid levels in aging, normal subjects

Lowe, V., Weigand, S. D., Senjem, M. L., Vemuri, P. D., Jordan, L., Kantarci, K. M., Boeve, B. F., Jack, C. R. J., Knopman, D. S. & Petersen, R. C., Jun 3 2014, In : Neurology. 82, 22, p. 1959-1967 9 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Fluorodeoxyglucose F18
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole
Pittsburgh
76 Citations (Scopus)

Association of lifetime intellectual enrichment with cognitive decline in the older population

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Machulda, M. M., Knopman, D. S., Mielke, M. M., Roberts, R. O., Geda, Y. E., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., 2014, In : JAMA Neurology. 71, 8, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

Occupations
Education
Population
Cognition
Dementia
50 Citations (Scopus)

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

Allen, M., Kachadoorian, M., Quicksall, Z., Zou, F., Chai, H. S., Younkin, C., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Krishnan, S., Nguyen, T., Ma, L., Malphrus, K., Lincoln, S., Bisceglio, G., Kolbert, C. P., Jen, J., Mukherjee, S., Kauwe, J. K., Crane, P. K. & 11 others, Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Parisi, J. E., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Jul 1 2014, In : Alzheimer's Research and Therapy. 6, 4, 39.

Research output: Contribution to journalArticle

Haplotypes
Alzheimer Disease
Gene Expression
Brain
Temporal Lobe
235 Citations (Scopus)

Association of Mediterranean diet with mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis

Singh, B., Parsaik, A. K., Mielke, M. M., Erwin, P. J., Knopman, D. S., Petersen, R. C. & Roberts, R. O., 2014, In : Journal of Alzheimer's Disease. 39, 2, p. 271-282 12 p.

Research output: Contribution to journalArticle

Mediterranean Diet
Meta-Analysis
Alzheimer Disease
Confidence Intervals
Cohort Studies
25 Citations (Scopus)

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K. K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Apolipoproteins E
Alzheimer Disease
Alleles
89 Citations (Scopus)

Association of type 2 diabetes with brain atrophy and cognitive impairment

Roberts, R. O., Knopman, D. S., Przybelski, S. A., Mielke, M. M., Kantarci, K. M., Preboske, G. M., Senjem, M. L., Pankratz, V. S., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., Apr 1 2014, In : Neurology. 82, 13, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Atrophy
Hypertension
Cognition
Brain
54 Citations (Scopus)

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

Van Blitterswijk, M., Mullen, B., Heckman, M. G., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M., Strong, M. J., Beach, T. G. & 17 others, Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., 2014, In : Neurobiology of Aging. 35, 10

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Open Reading Frames
Motor Neuron Disease
Motor Neurons
Angelman Syndrome