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Ronald Carl Petersen, MD

  • 114774 Citations
  • 149 Scopus h-Index
1974 …2019
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Research Output 1974 2019

Article
24 Citations (Scopus)

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K. K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journal › Article

Apolipoprotein E4
Amyloid
Apolipoproteins E
Alzheimer Disease
Alleles
137 Citations (Scopus)

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 1 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journal › Article

Intermediate Filaments
Alzheimer Disease
Light
Biomarkers
Cerebrospinal Fluid
24 Citations (Scopus)

Association of plasma total tau level with cognitive decline and risk of mild cognitive impairment or dementia in the Mayo Clinic study on aging

Mielke, M. M., Hagen, C. E., Wennberg, A. M. V., Airey, D. C., Savica, R., Knopman, D. S., Machulda, M. M., Roberts, R. O., Jack, C. R. J., Petersen, R. C. & Dage, J. L., Sep 1 2017, In : JAMA Neurology. 74, 9, p. 1073-1080 8 p.

Research output: Contribution to journal › Article

Dementia
Cognition
Brain
Aptitude
Cognitive Dysfunction
54 Citations (Scopus)

Association of prior stroke with cognitive function and cognitive impairment: A population-based study

Knopman, D. S., Roberts, R. O., Geda, Y. E., Boeve, B. F., Pankratz, V. S., Cha, R. H., Tangalos, E. G., Ivnik, R. J. & Petersen, R. C., May 2009, In : Archives of Neurology. 66, 5, p. 614-619 6 p.

Research output: Contribution to journal › Article

Cognition
Stroke
Population
Odds Ratio
Dementia
5 Citations (Scopus)

Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies

Zhan, Y., Clements, M. S., Roberts, R. O., Vassilaki, M., Druliner, B. R., Boardman, L. A., Petersen, R. C., Reynolds, C. A., Pedersen, N. L. & Hägg, S., Sep 1 2018, In : Neurobiology of Aging. 69, p. 111-116 6 p.

Research output: Contribution to journal › Article

Aptitude
Telomere
Meta-Analysis
Cohort Studies
Prospective Studies
88 Citations (Scopus)

Association of type 2 diabetes with brain atrophy and cognitive impairment

Roberts, R. O., Knopman, D. S., Przybelski, S. A., Mielke, M. M., Kantarci, K. M., Preboske, G. M., Senjem, M. L., Pankratz, V. S., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., Apr 1 2014, In : Neurology. 82, 13, p. 1132-1141 10 p.

Research output: Contribution to journal › Article

Type 2 Diabetes Mellitus
Atrophy
Hypertension
Cognition
Brain
59 Citations (Scopus)

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841.

Research output: Contribution to journal › Article

Random Allocation
Alzheimer Disease
Smoking
Odds Ratio
Mendelian Randomization Analysis
3 Citations (Scopus)

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles with Rates of Memory Decline among Individuals Without Dementia

Jack, C. R. J., Wiste, H. J., Therneau, T. M., Weigand, S. D., Knopman, D. S., Mielke, M. M., Lowe, V., Vemuri, P. D., Machulda, M. M., Schwarz, C., Gunter, J. L., Senjem, M. L., Graff-Radford, J., Jones, D. T., Roberts, R. O., Rocca, W. A. & Petersen, R. C., Jun 18 2019, In : JAMA - Journal of the American Medical Association. 321, 23, p. 2316-2325 10 p.

Research output: Contribution to journal › Article

Amyloid
Dementia
Biomarkers
Positron-Emission Tomography
National Institute on Aging (U.S.)
67 Citations (Scopus)

Asymmetric cortical degenerative syndromes: Clinical and radiologic correlations

Caselli, R. J., Jack, C. R. J., Petersen, R. C., Wahner, H. W. & Yanagihara, T., 1992, In : Neurology. 42, 8, p. 1462-1468 7 p.

Research output: Contribution to journal › Article

Single-Photon Emission-Computed Tomography
Nervous System
Primary Progressive Nonfluent Aphasia
Frontal Lobe
Atrophy
52 Citations (Scopus)

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

Van Blitterswijk, M., Mullen, B., Heckman, M. G., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M., Strong, M. J., Beach, T. G. & 17 others, Wszolek, Z. K., Lippa, C., Caselli, R. J., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., 2014, In : Neurobiology of Aging. 35, 10

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9
Open Reading Frames
Motor Neuron Disease
Motor Neurons
Angelman Syndrome
109 Citations (Scopus)

Ataxin-2 repeat-length variation and neurodegeneration

Ross, O. A., Rutherford, N. J., Baker, M., Soto-Ortolaza, A. I., Carrasquillo, M. M., DeJesus-Hernandez, M., Adamson, J., Li, M., Volkening, K., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Woodruff, B. K., Knopman, D. S., White, C. L., Van Gerpen, J. A. & 13 others, Meschia, J. F., Mackenzie, I. R., Boylan, K., Boeve, B. F., Miller, B. L., Strong, M. J., Uitti, R. J., Younkin, S. G., Graff Radford, N. R., Petersen, R. C., Wszolek, Z. K., Dickson, D. W. & Rademakers, R. V., Aug 2011, In : Human Molecular Genetics. 20, 16, p. 3207-3212 6 p., ddr227.

Research output: Contribution to journal › Article

Neurodegenerative Diseases
Amyotrophic Lateral Sclerosis
Progressive Supranuclear Palsy
Spinocerebellar Ataxias
Frontotemporal Lobar Degeneration
22 Citations (Scopus)

Atrial fibrillation, cognitive impairment, and neuroimaging

Graff-Radford, J., Madhavan, M., Vemuri, P. D., Rabinstein, A., Cha, R. H., Mielke, M. M., Kantarci, K. M., Lowe, V., Senjem, M. L., Gunter, J. L., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Roberts, R. O., 2015, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

Neuroimaging
Atrial Fibrillation
Infarction
Cerebrovascular Disorders
Cognitive Dysfunction
46 Citations (Scopus)

Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations

Whitwell, J. L., Jack, C. R. J., Boeve, B. F., Senjem, M. L., Baker, M., Ivnik, R. J., Knopman, D. S., Wszolek, Z. K., Petersen, R. C., Rademakers, R. V. & Josephs, K. A., Sep 2009, In : Neurology. 73, 13, p. 1058-1065 8 p.

Research output: Contribution to journal › Article

Microtubule-Associated Proteins
Atrophy
Temporal Lobe
Mutation
tau Proteins
120 Citations (Scopus)

Atrophy rates accelerate in amnestic mild cognitive impairment

Jack, C. R. J., Weigand, S. D., Shiung, M. M., Przybelski, S. A., O'Brien, P. C., Gunter, J. L., Knopman, D. S., Boeve, B. F., Smith, G. E. & Petersen, R. C., May 2008, In : Neurology. 70, 19 PART 2, p. 1740-1752 13 p.

Research output: Contribution to journal › Article

Atrophy
Alzheimer Disease
Brain
Cognitive Dysfunction
Magnetic Resonance Imaging
148 Citations (Scopus)

At the interface of sensory and motor dysfunctions and Alzheimer's disease

Albers, M. W., Gilmore, G. C., Kaye, J., Murphy, C., Wingfield, A., Bennett, D. A., Boxer, A. L., Buchman, A. S., Cruickshanks, K. J., Devanand, D. P., Duffy, C. J., Gall, C. M., Gates, G. A., Granholm, A. C., Hensch, T., Holtzer, R., Hyman, B. T., Lin, F. R., McKee, A. C., Morris, J. C. & 8 others, Petersen, R. C., Silbert, L. C., Struble, R. G., Trojanowski, J. Q., Verghese, J., Wilson, D. A., Xu, S. & Zhang, L. I., 2015, In : Alzheimer's and Dementia. 11, 1, p. 70-98 29 p.

Research output: Contribution to journal › Article

Alzheimer Disease
Education
National Institute on Aging (U.S.)
Neurobehavioral Manifestations
Central Nervous System
117 Citations (Scopus)

Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia

Josephs, K. A., Boeve, B. F., Duffy, J. R., Smith, G. E., Knopman, D. S., Parisi, J. E., Petersen, R. C. & Dickson, D. W., Aug 2005, In : Neurocase. 11, 4, p. 283-296 14 p.

Research output: Contribution to journal › Article

Broca Aphasia
Progressive Supranuclear Palsy
Apraxias
Primary Progressive Nonfluent Aphasia
Brain Stem

Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability

Hurtz, S., Chow, N., Watson, A. E., Somme, J. H., Goukasian, N., Hwang, K. S., Morra, J., Elashoff, D., Gao, S., Petersen, R. C., Aisen, P. S., Thompson, P. M. & Apostolova, L. G., Jan 1 2018, (Accepted/In press) In : NeuroImage: Clinical. 101574.

Research output: Contribution to journal › Article

Reproducibility of Results
Atrophy
Alzheimer Disease
Aptitude
Vitamin E
2 Citations (Scopus)

Automated detection of imaging features of disproportionately enlarged subarachnoid space hydrocephalus using machine learning methods

Gunter, N. B., Schwarz, C., Graff-Radford, J., Gunter, J. L., Jones, D. T., Graff Radford, N. R., Petersen, R. C., Knopman, D. S. & Jack, C. R. J., Jan 1 2018, (Accepted/In press) In : NeuroImage: Clinical.

Research output: Contribution to journal › Article

Subarachnoid Space
Hydrocephalus
Cerebrospinal Fluid
ROC Curve
Normal Pressure Hydrocephalus
134 Citations (Scopus)

Autonomic dysfunction in dementia with Lewy bodies

Thaisetthawatkul, P., Boeve, B. F., Benarroch, E. E., Sandroni, P., Ferman, T. J., Petersen, R. C. & Low, P. A., May 25 2004, In : Neurology. 62, 10, p. 1804-1809 6 p.

Research output: Contribution to journal › Article

Lewy Body Disease
Multiple System Atrophy
Parkinson Disease
Sweat
Autonomic Nervous System Diseases
10 Citations (Scopus)

Autonomic failure in Guamanian neurodegenerative disease

Low, P. A., Ahlskog, J. E., Petersen, R. C., Waring, S. C., Esteban-Santillan, C. & Kurland, L. T., Oct 1997, In : Neurology. 49, 4, p. 1031-1034 4 p.

Research output: Contribution to journal › Article

Neurodegenerative Diseases
Amyotrophic Lateral Sclerosis
Parkinsonian Disorders
Adrenergic Agents
Parkinson Disease
11 Citations (Scopus)

Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: A comparison of quantitative MRI and neuropsychological findings

Fearing, M. A., Bigler, E. D., Norton, M., Tschanz, J. A., Hulette, C., Leslie, C., Welsh-Bohmer, K., Anthony, J., Brookmeyer, R., Burke, J., Carlson, M., Christopher, E., Corcoran, C., David, M., Gagliardi, J., Green, R., Hart, A., Helms, M., Klein, L., Leslie, C. & 21 others, Morris, J., Munger, R., Onyike, C., Østbye, T., Petersen, R. C., Piercy, K., Pieper, C., Plassman, B., Rabins, P., Raj, P., Ray, R., Sanders, L., Steffens, D. C., Steinberg, M., Toohill, M., Toone, L., Townsend, J. J., Wengreen, H., West, N., Williams, M. & Wyse, B. W., Jul 2007, In : Journal of Clinical and Experimental Neuropsychology. 29, 5, p. 553-560 8 p.

Research output: Contribution to journal › Article

Autopsy
Alzheimer Disease
Magnetic Resonance Imaging
Outcome Assessment (Health Care)
Brain
56 Citations (Scopus)

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

Kantarci, K. M., Lowe, V., Boeve, B. F., Senjem, M. L., Tosakulwong, N., Lesnick, T. G., Spychalla, A. J., Gunter, J. L., Fields, J. A., Graff-Radford, J., Ferman, T. J., Jones, D. T., Murray, M. E., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., 2016, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journal › Article

Lewy Body Disease
Amyloid
Positron-Emission Tomography
Alzheimer Disease
Occipital Lobe
34 Citations (Scopus)

Aβ imaging: Feasible, pertinent, and vital to progress in Alzheimer's disease

Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C., Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R. J., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M., Selkoe, D. J. & 4 others, Sperling, R. A., Van Laere, K., Weiner, M. W. & Drzezga, A., Feb 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 209-219 11 p.

Research output: Contribution to journal › Article

Amyloid beta-Peptides
Radioisotopes
Positron-Emission Tomography
Alzheimer Disease
107 Citations (Scopus)

Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: A population-based study

Geda, Y. E., Roberts, R. O., Mielke, M. M., Knopman, D. S., Christianson, T. J. H., Pankratz, V. S., Boeve, B. F., Sochor, O., Tangalos, E. G., Petersen, R. C. & Rocca, W. A., May 1 2014, In : American Journal of Psychiatry. 171, 5, p. 572-581 10 p.

Research output: Contribution to journal › Article

Population
Psychiatry
Cognitive Dysfunction
Mild Cognitive Impairment
Depression
1 Citation (Scopus)

Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Whitwell, J. L. & Dickson, D. W., Jan 1 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

Tauopathies
DNA-Binding Proteins
Atrophy
Brain
Amygdala
51 Citations (Scopus)

Brain atrophy over time in genetic and sporadic frontotemporal dementia: A study of 198 serial magnetic resonance images

Whitwell, J. L., Boeve, B. F., Weigand, S. D., Senjem, M. L., Gunter, J. L., Baker, M. C., Dejesus-Hernandez, M., Knopman, D. S., Wszolek, Z. K., Petersen, R. C., Rademakers, R. V., Jack, C. R. J. & Josephs, K. A., May 1 2015, In : European Journal of Neurology. 22, 5, p. 745-752 8 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia
Atrophy
Microtubule-Associated Proteins
Magnetic Resonance Spectroscopy
Brain
362 Citations (Scopus)

Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI

Jack, C. R. J., Shiung, M. M., Weigand, S. D., O'Brien, P. C., Gunter, J. L., Boeve, B. F., Knopman, D. S., Smith, G. E., Ivnik, R. J., Tangalos, E. G. & Petersen, R. C., Oct 25 2005, In : Neurology. 65, 8, p. 1227-1231 5 p.

Research output: Contribution to journal › Article

Atrophy
Alzheimer Disease
Brain
Entorhinal Cortex
Cognitive Dysfunction
327 Citations (Scopus)

Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

Jack, C. R. J., Wiste, H. J., Vemuri, P. D., Weigand, S. D., Senjem, M. L., Zeng, G., Bernstein, M. A., Gunter, J. L., Pankratz, V. S., Aisen, P. S., Weiner, M. W., Petersen, R. C., Shaw, L. M., Trojanowski, J. Q. & Knopman, D. S., Nov 2010, In : Brain. 133, 11, p. 3336-3348 13 p.

Research output: Contribution to journal › Article

Amyloid
Atrophy
Alzheimer Disease
Magnetic Resonance Imaging
Brain
131 Citations (Scopus)

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Zou, F., Chai, H. S., Younkin, C. S., Allen, M., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Kouri, N., Kolbert, C. P. & 11 others, Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Jun 2012, In : PLoS Genetics. 8, 6, e1002707.

Research output: Contribution to journal › Article

Genome-Wide Association Study
human diseases
brain
genome
Brain
106 Citations (Scopus)

Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference

Morley, J. E., Morris, J. C., Berg-Weger, M., Borson, S., Carpenter, B. D., del Campo, N., Dubois, B., Fargo, K., Fitten, L. J., Flaherty, J. H., Ganguli, M., Grossberg, G. T., Malmstrom, T. K., Petersen, R. C., Rodriguez, C., Saykin, A. J., Scheltens, P., Tangalos, E. G., Verghese, J., Wilcock, G. & 3 others, Winblad, B., Woo, J. & Vellas, B., Sep 1 2015, In : Journal of the American Medical Directors Association. 16, 9, p. 731-739 9 p.

Research output: Contribution to journal › Article

Consensus
Health
Brain
Delivery of Health Care
Centers for Medicare and Medicaid Services (U.S.)
118 Citations (Scopus)

Brain injury biomarkers are not dependent on β-amyloid in normal elderly

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Roberts, R. O., Boeve, B. F. & Petersen, R. C., Apr 2013, In : Annals of Neurology. 73, 4, p. 472-480 9 p.

Research output: Contribution to journal › Article

Amyloid
Brain Injuries
Biomarkers
Positron-Emission Tomography
Alzheimer Disease
112 Citations (Scopus)

Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial

Grundman, M., Sencakova, D., Jack, C. R. J., Petersen, R. C., Kim, H. T., Schultz, A., Weiner, M. F., DeCarli, C., DeKosky, S. T., Van Dyck, C., Thomas, R. G. & Thal, L. J., Aug 2002, In : Journal of Molecular Neuroscience. 19, 1-2, p. 23-27 5 p.

Research output: Contribution to journal › Article

Brain
Magnetic Resonance Imaging
Pathology
Deterioration
Cognition
22 Citations (Scopus)

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R. C., Jack, C. R. J., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D. S., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In : Scientific Reports. 8, 1, 4103.

Research output: Contribution to journal › Article

Biomarkers
Brain
Patient treatment
Electric network analysis
Magnetic resonance imaging
31 Citations (Scopus)

Brain regional correlation of amyloid-β with synapses and apolipoprotein e in non-demented individuals: Potential mechanisms underlying regional vulnerability to amyloid-β accumulation

Shinohara, M., Petersen, R. C., Dickson, D. W. & Bu, G. D., Apr 2013, In : Acta Neuropathologica. 125, 4, p. 535-547 13 p.

Research output: Contribution to journal › Article

Apolipoproteins
Apolipoproteins E
Amyloid
Synapses
Insulysin
13 Citations (Scopus)

Brain structure and cerebrovascular risk in cognitively impaired patients: Shanghai community brain health initiative-pilot phase

He, J., Iosif, A. M., Lee, D. Y., Martinez, O., Chu, S., Carmichael, O., Mortimer, J. A., Zhao, Q., Ding, D., Guo, Q., Galasko, D., Salmon, D. P., Dai, Q., Wu, Y., Petersen, R. C., Hong, Z., Borenstein, A. R. & DeCarli, C., Oct 2010, In : Archives of Neurology. 67, 10, p. 1231-1237 7 p.

Research output: Contribution to journal › Article

Cognition
Dementia
Magnetic Resonance Imaging
Blood Pressure
Health
1 Citation (Scopus)

Brain tau deposition linked to systemic causes of death in normal elderly

Josephs, K. A., Tosakulwong, N., Weigand, S. D., Murray, M. E., Whitwell, J. L., Parisi, J. E., Dickson, D. W. & Petersen, R. C., Feb 1 2017, In : Neurobiology of Aging. 50, p. 163-166 4 p.

Research output: Contribution to journal › Article

Cause of Death
alpha-Synuclein
DNA-Binding Proteins
Brain
Amyloid beta-Peptides
176 Citations (Scopus)

Brain β-amyloid load approaches a plateau

Jack, C. R. J., Wiste, H. J., Lesnick, T. G., Weigand, S. D., Knopman, D. S., Vemuri, P. D., Pankratz, V. S., Senjem, M. L., Gunter, J. L., Mielke, M. M., Lowe, V., Boeve, B. F. & Petersen, R. C., Mar 5 2013, In : Neurology. 80, 10, p. 890-896 7 p.

Research output: Contribution to journal › Article

Amyloid
Brain
Plateau
Alzheimer Disease
Sigmoid Colon
62 Citations (Scopus)

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

Van Blitterswijk, M., Baker, M. C., Hernandez, M., Ghidoni, R., Benussi, L., Finger, E., Hsiung, G. Y. R., Kelley, B. J., Murray, M. E., Rutherford, N. J., Brown, P. E., Ravenscroft, T., Mullen, B., Ash, P. E. A., Bieniek, K. F., Hatanpaa, K. J., Karydas, A., Wood, E. M., Coppola, G., Bigio, E. H. & 22 others, Lippa, C., Strong, M. J., Beach, T. G., Knopman, D. S., Huey, E. D., Mesulam, M., Bird, T., White, C. L., Kertesz, A., Geschwind, D. H., Van Deerlin, V. M., Petersen, R. C., Binetti, G., Miller, B. L., Petrucelli, L., Wszolek, Z. K., Boylan, K. B., Graff Radford, N. R., MacKenzie, I. R., Boeve, B. F., Dickson, D. W. & Rademakers, R. V., Oct 8 2013, In : Neurology. 81, 15, p. 1332-1341 10 p.

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 9
Open Reading Frames
Mutation
Southern Blotting
Immunohistochemistry
21 Citations (Scopus)

Caloric intake, aging, and mild cognitive impairment: A population-based study

Geda, Y. E., Ragossnig, M., Roberts, L. A., Roberts, R. O., Pankratz, V. S., Christianson, T. J. H., Mielke, M. M., Levine, J. A., Boeve, B. F., Sochor, O., Tangalos, E. G., Knopman, D. S. & Petersen, R. C., 2013, In : Journal of Alzheimer's Disease. 34, 2, p. 501-507 7 p.

Research output: Contribution to journal › Article

Energy Intake
Population
Odds Ratio
Confidence Intervals
Apolipoprotein E4
78 Citations (Scopus)

Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease

Carrillo, M. C., Brashear, H. R., Logovinsky, V., Ryan, J. M., Feldman, H. H., Siemers, E. R., Abushakra, S., Hartley, D. M., Petersen, R. C., Khachaturian, A. S. & Sperling, R. A., Mar 2013, In : Alzheimer's and Dementia. 9, 2, p. 123-131 9 p.

Research output: Contribution to journal › Article

Secondary Prevention
Alzheimer Disease
National Institute on Aging (U.S.)
Research
Asymptomatic Diseases
41 Citations (Scopus)

Cardiac disease associated with increased risk of nonamnestic cognitive impairment

Roberts, R. O., Geda, Y. E., Knopman, D. S., Cha, R. H., Pankratz, V. S., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Mielke, M. M. & Petersen, R. C., Mar 2013, In : JAMA Neurology. 70, 3, p. 374-382 9 p.

Research output: Contribution to journal › Article

Heart Diseases
Dementia
Vascular Dementia
Cognitive Dysfunction
Cognitive Impairment

Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging

Scharf, E. L., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Mielke, M. M., Knopman, D. S., Preboske, G. M., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Machulda, M., Kantarci, K., Petersen, R. C., Jack, C. R. & Vemuri, P., Nov 1 2019, In : Stroke. 50, 11, p. 3037-3044 8 p.

Research output: Contribution to journal › Article

Health
Hypertension
Glucose
White Matter
Fasting
2 Citations (Scopus)

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

Singanamalli, A., Wang, H., Madabhushi, A., Weiner, M., Aisen, P., Petersen, R. C., Jack, C. R. J., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D. S., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific Reports. 7, 1, 8137.

Research output: Contribution to journal › Article

Early Diagnosis
Alzheimer Disease
Area Under Curve
Neuroimaging
Proteomics
126 Citations (Scopus)

Cascading network failure across the Alzheimer's disease spectrum

Jones, D. T., Knopman, D. S., Gunter, J. L., Graff-Radford, J., Vemuri, P. D., Boeve, B. F., Petersen, R. C., Weiner, M. W. & Jack, C. R. J., Dec 21 2015, In : Brain. 139, 2, p. 547-562 16 p.

Research output: Contribution to journal › Article

Alzheimer Disease
Neuroimaging
Amyloid Plaques
Brain
Frontal Lobe
55 Citations (Scopus)

Caudate atrophy on MRI is a characteristic feature of FTLD-FUS

Josephs, K. A., Whitwell, J. L., Parisi, J. E., Petersen, R. C., Boeve, B. F., Jack, C. R. J. & Dickson, D. W., Jul 2010, In : European Journal of Neurology. 17, 7, p. 969-975 7 p.

Research output: Contribution to journal › Article

Frontotemporal Lobar Degeneration
Atrophy
Frontal Lobe
67 Citations (Scopus)

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Williams, K. L., Topp, S., Yang, S., Smith, B., Fifita, J. A., Warraich, S. T., Zhang, K. Y., Farrawell, N., Vance, C., Hu, X., Chesi, A., Leblond, C. S., Lee, A., Rayner, S. L., Sundaramoorthy, V., Dobson-Stone, C., Molloy, M. P., Van Blitterswijk, M., Dickson, D. W., Petersen, R. C. & 48 others, Graff Radford, N. R., Boeve, B. F., Murray, M. E., Pottier, C., Don, E., Winnick, C., McCann, E. P., Hogan, A., Daoud, H., Levert, A., Dion, P. A., Mitsui, J., Ishiura, H., Takahashi, Y., Goto, J., Kost, J., Gellera, C., Gkazi, A. S., Miller, J., Stockton, J., Brooks, W. S., Boundy, K., Polak, M., Muñoz-Blanco, J. L., Esteban-Pérez, J., Rábano, A., Hardiman, O., Morrison, K. E., Ticozzi, N., Silani, V., De Belleroche, J., Glass, J. D., Kwok, J. B. J., Guillemin, G. J., Chung, R. S., Tsuji, S., Brown, R. H., García-Redondo, A., Rademakers, R. V., Landers, J. E., Gitler, A. D., Rouleau, G. A., Cole, N. J., Yerbury, J. J., Atkin, J. D., Shaw, C. E., Nicholson, G. A. & Blair, I. P., Apr 15 2016, In : Nature Communications. 7, 11253.

Research output: Contribution to journal › Article

Ubiquitinated Proteins
mutations
Ubiquitin-Protein Ligase Complexes
proteins
Mutation
43 Citations (Scopus)

Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers

Gendron, T. D., Van Blitterswijk, M., Bieniek, K. F., Daughrity, L. M., Jiang, J., Rush, B. K., Pedraza, O. D., Lucas, J. A., Murray, M. E., Desaro, P., Robertson, A., Overstreet, K., Thomas, C. S., Crook, J., Castanedes-Casey, M., Rousseau, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C. & 9 others, Boeve, B. F., Graff Radford, N. R., Rademakers, R. V., Lagier-Tourenne, C., Edbauer, D., Cleveland, D. W., Dickson, D. W., Petrucelli, L. & Boylan, K. B., Oct 26 2015, In : Acta Neuropathologica. 130, 4, p. 559-573 15 p.

Research output: Contribution to journal › Article

Frontotemporal Lobar Degeneration
Chromosomes, Human, Pair 9
Open Reading Frames
Amyotrophic Lateral Sclerosis
Cerebellum
17 Citations (Scopus)

Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging

Wennberg, A. M. V., Savica, R., Hagen, C. E., Roberts, R. O., Knopman, D. S., Hollman, J. H., Vemuri, P. D., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., 2016, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journal › Article

Gait
Amyloid
Gyrus Cinguli
Linear Models
Normal Pressure Hydrocephalus
3 Citations (Scopus)

Cerebral microbleeds: Prevalence and relationship to amyloid burden

Graff-Radford, J., Botha, H., Rabinstein, A., Gunter, J. L., Przybelski, S. A., Lesnick, T., Huston, J., Flemming, K., Preboske, G. M., Senjem, M. L., Brown, R. D. J., Mielke, M. M., Roberts, R. O., Lowe, V., Knopman, D. S., Petersen, R. C., Kremers, W. K., Vemuri, P. D., Jack, C. R. J. & Kantarci, K. M., Jan 15 2019, In : Neurology. 92, 3, p. e253-e262

Research output: Contribution to journal › Article

Amyloid
Parietal Lobe
Logistic Models
Population
Hypertension
1201 Citations (Scopus)

Cerebrospinal fluid biomarker signature in alzheimer's disease neuroimaging initiative subjects

Shaw, L. M., Vanderstichele, H., Knapik-Czajka, M., Clark, C. M., Aisen, P. S., Petersen, R. C., Blennow, K., Soares, H., Simon, A., Lewczuk, P., Dean, R., Siemers, E., Potter, W., Lee, V. M. Y. & Trojanowski, J. Q., Apr 2009, In : Annals of Neurology. 65, 4, p. 403-413 11 p.

Research output: Contribution to journal › Article

Neuroimaging
Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
Autopsy