• 118790 Citations
  • 154 Scopus h-Index
1974 …2020

Research output per year

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Research Output

Article

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Jack, C. R. J., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C. & Trojanowski, J. Q., Jan 2010, In : The Lancet Neurology. 9, 1, p. 119-128 10 p.

Research output: Contribution to journalArticle

2438 Scopus citations

Hypothyroidism and risk of mild cognitive impairment in elderly persons a population-based study

Parsaik, A. K., Singh, B., Roberts, R. O., Pankratz, S., Edwards, K. K., Geda, Y. E., Gharib, H., Boeve, B. F., Knopman, D. S. & Petersen, R. C., Feb 2014, In : JAMA Neurology. 71, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
194 Scopus citations

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

International Frontotemporal Dementia Genomics Consortium, Jan 1 2019, In : Nature Medicine. 25, 1, p. 152-164 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R. J., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J. & Saykin, A. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 739 1 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

Fiandaca, M. S., Kapogiannis, D., Mapstone, M., Boxer, A., Eitan, E., Schwartz, J. B., Abner, E. L., Petersen, R. C., Federoff, H. J., Miller, B. L. & Goetzl, E. J., Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. 600-607.e1

Research output: Contribution to journalArticle

242 Scopus citations

Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies

Graff-Radford, J., Boeve, B. F., Pedraza, O. D., Ferman, T. J., Przybelski, S., Lesnick, T. G., Vemuri, P. D., Senjem, M. L., Smith, G. E., Knopman, D. S., Lowe, V., Jack, C. R. J., Petersen, R. C. & Kantarci, K. M., Aug 2012, In : Brain. 135, 8, p. 2470-2477 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
36 Scopus citations

Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis

Zeydan, B., Lowe, V. J., Reichard, R. R., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Parisi, J. E., Machulda, M. M., Vemuri, P., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R., Kantarci, O. H. & Kantarci, K., Jan 1 2020, (Accepted/In press) In : Annals of neurology.

Research output: Contribution to journalArticle

Open Access

Imaging correlates of pathology in corticobasal syndrome

Whitwell, J. L., Jack, C. R. J., Boeve, B. F., Parisi, J. E., Ahlskog, J. E., Drubach, D., Senjem, M. L., Knopman, D. S., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Nov 23 2010, In : Neurology. 75, 21, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

128 Scopus citations

Imaging correlates of posterior cortical atrophy

Whitwell, J. L., Jack, C. R. J., Kantarci, K. M., Weigand, S. D., Boeve, B. F., Knopman, D. S., Drubach, D., Tang-Wai, D. F., Petersen, R. C. & Josephs, K. A., Jul 2007, In : Neurobiology of Aging. 28, 7, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

125 Scopus citations
16 Scopus citations
36 Scopus citations

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

International FTD-Genomics Consortium, Jan 1 2018, In : PLoS Medicine. 15, 1, e1002487.

Research output: Contribution to journalArticle

32 Scopus citations

Impact of apolipoprotein ε4-cerebrospinal fluid beta-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment

Chiang, G. C., Insel, P. S., Tosun, D., Schuff, N., Truran-Sacrey, D., Raptentsetsang, S. T., Thompson, P. M., Reiman, E. M., Jack, C. R. J., Fox, N. C., Jagust, W. J., Harvey, D. J., Beckett, L. A., Gamst, A., Aisen, P. S., Petersen, R. C. & Weiner, M. W., Sep 2011, In : Alzheimer's and Dementia. 7, 5, p. 514-520 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

Shinohara, M., Murray, M. E., Frank, R. D., Shinohara, M., Deture, M., Yamazaki, Y., Tachibana, M., Atagi, Y., Davis, M. D., Liu, C-C., Zhao, N., Painter, M. M., Petersen, R. C., Fryer, J. D., Crook, J., Dickson, D. W., Bu, G. D. & Kanekiyo, T., May 14 2016, (Accepted/In press) In : Acta Neuropathologica. p. 1-10 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014

Weiner, M. W., Veitch, D. P., Aisen, P. S., Beckett, L. A., Cairns, N. J., Cedarbaum, J., Donohue, M. C., Green, R. C., Harvey, D., Jack, C. R. J., Jagust, W., Morris, J. C., Petersen, R. C., Saykin, A. J., Shaw, L., Thompson, P. M., Toga, A. W. & Trojanowski, J. Q., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 865-884 20 p.

Research output: Contribution to journalArticle

95 Scopus citations

Implicit learning of sequential regularities and spatial contexts in corticobasal syndrome

Negash, S., Boeve, B. F., Geda, Y. E., Smith, G. E., Knopman, D. S., Ivnik, R. J., Howard, D. V., Howard, J. H. & Petersen, R. C., Jun 2007, In : Neurocase. 13, 3, p. 133-143 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Improved DTI registration allows voxel-based analysis that outperforms Tract-Based Spatial Statistics

Schwarz, C., Reid, R. I., Gunter, J. L., Senjem, M. L., Przybelski, S. A., Zuk, S. M., Whitwell, J. L., Vemuri, P. D., Josephs, K. A., Kantarci, K. M., Thompson, P. M., Petersen, R. C. & Jack, C. R. J., Jul 1 2014, In : NeuroImage. 94, p. 65-78 14 p.

Research output: Contribution to journalArticle

89 Scopus citations

Incidence and causes of nondegenerative nonvascular dementia: A population-based study

Knopman, D. S., Petersen, R. C., Cha, R. H., Edland, S. D. & Rocca, W. A., Feb 2006, In : Archives of Neurology. 63, 2, p. 218-221 4 p.

Research output: Contribution to journalArticle

65 Scopus citations

Incidence of amyotrophic lateral sclerosis and of the parkinsonism-dementia complex of Guam, 1950-1989

Waring, S. C., Esteban-Santillan, C., Reed, D. M., Craig, U. K., Labarthe, D. R., Petersen, R. C. & Kurland, L. T., 2004, In : Neuroepidemiology. 23, 4, p. 192-200 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Incidence of Convexal Subarachnoid Hemorrhage in the Elderly: The Mayo Clinic Study of Aging

Yost, M., Fiebelkorn, C. A., Rabinstein, A. A., Klaas, J., Aakre, J. A., Brown, R. D., Mielke, M. M., Knopman, D. S., Lowe, V., Petersen, R. C., Jack, C. R., Vemuri, P. & Graff-Radford, J., Dec 2019, In : Journal of Stroke and Cerebrovascular Diseases. 28, 12, 104451.

Research output: Contribution to journalArticle

Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging

Knopman, D. S., Roberts, R. O., Pankratz, V. S., Cha, R. H., Rocca, W. A., Mielke, M. M., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Geda, Y. E. & Petersen, R. C., 2014, In : American Journal of Epidemiology. 180, 4, p. 414-423 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Incidence of frontotemporal disorders in Olmsted County: A population-based study

Turcano, P., Stang, C. D., Mielke, M. M., Martin, P. R., Upadhyaya, S. G., Josephs, K. A., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Savica, R., Jan 1 2019, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Incident dementia in women is preceded by weight loss by at least a decade

Knopman, D. S., Edland, S. D., Cha, R. H., Petersen, R. C. & Rocca, W. A., Aug 2007, In : Neurology. 69, 8, p. 739-746 8 p.

Research output: Contribution to journalArticle

141 Scopus citations

Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies

Ferman, T. J., Boeve, B. F., Smith, G. E., Lin, S. C., Silber, M. H., Pedraza, O. D., Wszolek, Z. K., Graff Radford, N. R., Uitti, R., Van Gerpen, J. A., Pao, W., Knopman, D. S., Pankratz, V. S., Kantarci, K. M., Boot, B., Parisi, J. E., Dugger, B. N., Fujishiro, H., Petersen, R. C. & Dickson, D. W., Aug 30 2011, In : Neurology. 77, 9, p. 875-882 8 p.

Research output: Contribution to journalArticle

163 Scopus citations

Increased Risk of Type 2 Diabetes in Alzheimer Disease

Janson, J., Laedtke, T., Parisi, J. E., O'Brien, P., Petersen, R. C. & Butler, P. C., Feb 2004, In : Diabetes. 53, 2, p. 474-481 8 p.

Research output: Contribution to journalArticle

542 Scopus citations
15 Scopus citations

In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers

DeJesus-Hernandez, M., Finch, N. C. A., Wang, X., Gendron, T. D., Bieniek, K. F., Heckman, M. G., Vasilevich, A., Murray, M. E., Rousseau, L., Weesner, R., Lucido, A., Parsons, M., Chew, J., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Boeve, B. F., Graff Radford, N. R., de Boer, J. & 6 others, Asmann, Y., Petrucelli, L., Boylan, K. B., Dickson, D. W., Van Blitterswijk, M. & Rademakers, R. V., May 15 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-15 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Indicators of amyloid burden in a population-based study of cognitively normal elderly

Mielke, M. M., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V., Roberts, R. O., Geda, Y. E., Swenson-Dravis, D. M., Boeve, B. F., Senjem, M. L., Vemuri, P. D., Petersen, R. C. & Jack, C. R. J., Oct 9 2012, In : Neurology. 79, 15, p. 1570-1577 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort

Mielke, M. M., Machulda, M. M., Hagen, C. E., Christianson, T. J., Roberts, R. O., Knopman, D. S., Vemuri, P. D., Lowe, V., Kremers, W. K., Jack, C. R. J. & Petersen, R. C., 2015, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

18 Scopus citations

Influence of apolipoprotein e ε4 on rates of cognitive and functional decline in mild cognitive impairment

Whitehair, D. C., Sherzai, A., Emond, J., Raman, R., Aisen, P. S., Petersen, R. C. & Fleisher, A. S., Sep 2010, In : Alzheimer's and Dementia. 6, 5, p. 412-419 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
1 Scopus citations

Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

Kim, S., Swaminathan, S., Inlow, M., Risacher, S. L., Nho, K., Shen, L., Foroud, T. M., Petersen, R. C., Aisen, P. S., Soares, H., Toledo, J. B., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., McDonald, B. C., Farlow, M. R., Ghetti, B. & Saykin, A. J., Jul 23 2013, In : PLoS One. 8, 7, e70269.

Research output: Contribution to journalArticle

43 Scopus citations

Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia

Vassilaki, M., Aakre, J. A., Knopman, D. S., Kremers, W. K., Mielke, M. M., Geda, Y. E., Machulda, M. M., Al Fakir, R., Undavalli, C., Roberts, R. O. & Petersen, R. C., Nov 1 2019, In : Age and Ageing. 48, 6, p. 888-894 7 p.

Research output: Contribution to journalArticle

Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: Evidence of effect modification by apolipoprotein E (APOE)

Edland, S. D., Wavrant-De Vriesé, F., Compton, D., Smith, G. E., Ivnik, R., Boeve, B. F., Tangalos, E. G. & Petersen, R. C., Jul 10 2003, In : Neuroscience Letters. 345, 1, p. 21-24 4 p.

Research output: Contribution to journalArticle

51 Scopus citations

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

9 Scopus citations

Interleukin-1A polymorphism is not associated with late onset Alzheimer's disease

Fidani, L., Goulas, A., Mirtsou, V., Petersen, R. C., Tangalos, E. G., Crook, R. & Hardy, J., Apr 19 2002, In : Neuroscience Letters. 323, 1, p. 81-83 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Investigating statistical epistasis in complex disorders

Turton, J. C., Bullock, J., Medway, C., Shi, H., Brown, K., Belbin, O., Kalsheker, N., Carrasquillo, M. M., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Younkin, S. G. & Morgan, K., 2011, In : Journal of Alzheimer's Disease. 25, 4, p. 635-644 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Guerreiro, R., Ross, O. A., Kun-Rodrigues, C., Hernandez, D. G., Orme, T., Eicher, J. D., Shepherd, C. E., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L., Honig, L. S., Marder, K. & 45 others, Lemstra, A., Rogaeva, E., St George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff Radford, N. R., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J. & Bras, J., Jan 1 2018, In : The Lancet Neurology. 17, 1, p. 64-74 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

Belbin, O., Carrasquillo, M. M., Crump, M., Culley, O. J., Hunter, T. A., Ma, L., Bisceglio, G., Zou, F., Allen, M., Dickson, D. W., Graff Radford, N. R., Petersen, R. C., Morgan, K. & Younkin, S. G., Mar 2011, In : Human Genetics. 129, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Investigation of white matter PiB uptake as a marker of white matter integrity

Zeydan, B., Schwarz, C., Lowe, V., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Kremers, W. K., Senjem, M. L., Gunter, J. L., Min, H. K., Vemuri, P. D., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Kantarci, O. H. & Kantarci, K. M., Apr 1 2019, In : Annals of Clinical and Translational Neurology. 6, 4, p. 678-688 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
14 Scopus citations

Is the Apolipoprotein E Genotype a Biomarker for Mild Cognitive Impairment? Findings From a Nationally Representative Study

Brainerd, C. J., Reyna, V. F., Petersen, R. C., Smith, G. E. & Taub, E. S., Nov 2011, In : Neuropsychology. 25, 6, p. 679-689 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials

Japanese Alzheimer's Disease Neuroimaging Initiative & Alzheimer's Disease Neuroimaging Initiative, Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

16 Scopus citations

Joint associations of β-amyloidosis and cortical thickness with cognition

Knopman, D. S., Lundt, E. S., Therneau, T. M., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T., Petersen, R. C. & Jack, C. R. J., May 1 2018, In : Neurobiology of Aging. 65, p. 121-131 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ketamine: Behavioral effects of subanesthetic doses

Ghoneim, M. M., Hinrichs, J. V., Mewaldt, S. P. & Petersen, R. C., 1985, In : Journal of Clinical Psychopharmacology. 5, 2, p. 70-77 8 p.

Research output: Contribution to journalArticle

133 Scopus citations

Large-scale genomics unveil polygenic architecture of human cortical surface area

Chen, C. H., Peng, Q., Schork, A. J., Lo, M. T., Fan, C. C., Wang, Y., Desikan, R. S., Bettella, F., Hagler, D. J., Westlye, L. T., Kremen, W. S., Jernigan, T. L., Le Hellard, S., Steen, V. M., Espeseth, T., Huentelman, M., Håberg, A. K., Agartz, I., Djurovic, S., Andreassen, O. A. & 86 others, Schork, N., Dale, A. M., McCabe, C., Chang, L., Akshoomoff, N., Newman, E., Ernst, T., Van Zijl, P., Kuperman, J., Murray, S., Bloss, C., Appelbaum, M., Gamst, A., Thompson, W., Bartsch, H., Weiner, M., Aisen, P., Petersen, R. C., Jack, C. R. J., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulman, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M. A., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P. D., Jones, D. T., Kantarci, K. M., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V. M. Y., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Frank, R., Buckholtz, N., Albert, M. & Hsiao, J., Jul 20 2015, In : Nature Communications. 6, 7549.

Research output: Contribution to journalArticle

20 Scopus citations

Late-onset Alzheimer disease ge

Carrasquillo, M. M., Khan, Q. U. A., Murray, M. E., Krishnan, S., Aakre, J., Pankratz, V. S., Nguyen, T., Ma, L., Bisceglio, G., Petersen, R. C., Younkin, S. G., Dickson, D. W., Boeve, B. F., Graff Radford, N. R. & Taner, N., Apr 22 2014, In : Neurology. 82, 16, p. 1455-1462 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Late-onset Alzheimer disease risk variants mark brain regulatory loci

Allen, M., Kachadoorian, M., Carrasquillo, M. M., Karhade, A., Manly, L., Burgess, J. D., Wang, C., Serie, D., Wang, X., Siuda, J., Zou, F., Chai, H. S., Younkin, C., Crook, J., Medway, C., Nguyen, T., Ma, L., Malphrus, K., Lincoln, S., Petersen, R. C. & 5 others, Graff Radford, N. R., Asmann, Y., Dickson, D. W., Younkin, S. G. & Taner, N., Aug 1 2015, In : Neurology: Genetics. 1, 2, e15.

Research output: Contribution to journalArticle

25 Scopus citations