• 121452 Citations
  • 155 Scopus h-Index
1974 …2020

Research output per year

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Research Output

2020

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 3869.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Brain amyloid, cortical thickness, and changes in activities of daily living

Vassilaki, M., Aakre, J. A., Kremers, W. K., Lesnick, T. G., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Butler, L., Traber, M., Vemuri, P., Lowe, V. J., Jack, C. R., Roberts, R. O. & Petersen, R. C., Jan 1 2020, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access

Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele

Ghisays, V., Goradia, D. D., Protas, H., Bauer, R. J., Devadas, V., Tariot, P. N., Lowe, V. J., Knopman, D. S., Petersen, R. C., Jack, C. R., Caselli, R. J., Su, Y., Chen, K. & Reiman, E. M., Apr 1 2020, In : Alzheimer's and Dementia. 16, 4, p. 598-609 12 p.

Research output: Contribution to journalArticle

Cardiorespiratory Fitness and Brain Volumes

Petersen, R. C., Joyner, M. J. & Jack, C. R., Jan 2020, In : Mayo Clinic proceedings. 95, 1, p. 6-8 3 p.

Research output: Contribution to journalEditorial

Open Access

Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging

Graff-Radford, J., Lesnick, T., Rabinstein, A. A., Gunter, J., Aakre, J., Przybelski, S. A., Spychalla, A. J., Huston, J., Brown, R. D., Mielke, M. M., Lowe, V. J., Knopman, D. S., Petersen, R. C., Jack, C. R., Vemuri, P., Kremers, W. & Kantarci, K., Jan 14 2020, In : Neurology. 94, 2, p. e190-e199

Research output: Contribution to journalArticle

Corrigendum to “Prosodic and phonetic subtypes of primary progressive apraxia of speech” [Brain Lang. 184 (2018) 54–65](S0093934X17302638)(10.1016/j.bandl.2018.06.004)

Utianski, R. L., Duffy, J. R., Clark, H. M., Strand, E. A., Botha, H., Schwarz, C. G., Machulda, M. M., Senjem, M. L., Spychalla, A. J., Jack, C. R., Petersen, R. C., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., Jun 2020, In : Brain and Language. 205, 104792.

Research output: Contribution to journalComment/debate

Open Access

Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes

Buciuc, M., Wennberg, A. M., Weigand, S. D., Murray, M. E., Senjem, M. L., Spychalla, A. J., Boeve, B. F., Knopman, D. S., Jack, C. R., Kantarci, K., Parisi, J. E., Dickson, D. W., Petersen, R. C., Whitwell, J. L. & Josephs, K. A., Jan 1 2020, In : Journal of Alzheimer's Disease. 73, 4, p. 1511-1523 13 p.

Research output: Contribution to journalArticle

Exposure to surgery with general anaesthesia during adult life is not associated with increased brain amyloid deposition in older adults

Sprung, J., Warner, D. O., Knopman, D. S., Petersen, R. C., Mielke, M. M., Jack, C. R., Lowe, V. J., Martin, D. P., Hanson, A. C., Schroeder, D. R., Przybelski, S. A., Schulte, P. J., Weingarten, T. N. & Vemuri, P., May 2020, In : British journal of anaesthesia. 124, 5, p. 594-602 9 p.

Research output: Contribution to journalArticle

Identification from MRI with Face-Recognition Software. Reply

Schwarz, C. G., Petersen, R. C. & Jack, C. R., Jan 30 2020, In : The New England journal of medicine. 382, 5, 1 p.

Research output: Contribution to journalLetter

Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis

Zeydan, B., Lowe, V. J., Reichard, R. R., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Parisi, J. E., Machulda, M. M., Vemuri, P., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R., Kantarci, O. H. & Kantarci, K., Apr 1 2020, In : Annals of neurology. 87, 4, p. 556-567 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Issues and Questions Surrounding Screening for Cognitive Impairment in Older Patients

Petersen, R. C. & Yaffe, K., Feb 25 2020, In : JAMA - Journal of the American Medical Association. 323, 8, p. 722-724 3 p.

Research output: Contribution to journalEditorial

Linear vs volume measures of ventricle size: Relation to present and future gait and cognition

Crook, J. E., Gunter, J. L., Ball, C. T., Jones, D. T., Graff-Radford, J., Knopman, D. S., Boeve, B. F., Petersen, R. C., Jack, C. R. & Graff-Radford, N. R., Feb 4 2020, In : Neurology. 94, 5, p. e549-e556

Research output: Contribution to journalArticle

Longitudinal flortaucipir ([18F]AV-1451) PET imaging in primary progressive apraxia of speech

Utianski, R. L., Martin, P. R., Botha, H., Schwarz, C. G., Duffy, J. R., Petersen, R. C., Knopman, D. S., Clark, H. M., Butts, A. M., Machulda, M. M., Jack, C. R., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., Mar 2020, In : Cortex. 124, p. 33-43 11 p.

Research output: Contribution to journalArticle

MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous

Josephs, K. A., Tosakulwong, N., Graff-Radford, J., Weigand, S. D., Buciuc, M., Machulda, M. M., Jones, D. T., Schwarz, C. G., Senjem, M. L., Ertekin-Taner, N., Kantarci, K., Boeve, B. F., Knopman, D. S., Jack, C. R., Petersen, R. C., Lowe, V. J. & Whitwell, J. L., Jan 1 2020, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access

Preoperative cognitive impairment associated with oversedation during recovery from anesthesia

Kruthiventi, S. C., Laporta, M. L., Deljou, A., Knopman, D. S., Petersen, R. C., Schroeder, D. R., Sprung, J. & Weingarten, T. N., Jan 1 2020, (Accepted/In press) In : Journal of Anesthesia.

Research output: Contribution to journalArticle

Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging

Neth, B. J., Graff-Radford, J., Mielke, M. M., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Reid, R. I., Senjem, M. L., Lowe, V. J., Machulda, M. M., Petersen, R. C., Jr, C. R. J., Knopman, D. S. & Vemuri, P., Jan 9 2020, In : Frontiers in Aging Neuroscience. 11, 355.

Research output: Contribution to journalArticle

Open Access

β-Amyloid PET and neuropathology in dementia with Lewy bodies

Kantarci, K., Lowe, V. J., Chen, Q., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Jack, C. R., Graff-Radford, J., Jones, D. T., Knopman, D. S., Graff-Radford, N., Ferman, T. J., Parisi, J. E., Dickson, D. W., Petersen, R. C., Boeve, B. F. & Murray, M. E., Jan 21 2020, In : Neurology. 94, 3, p. e282-e291

Research output: Contribution to journalArticle

Open Access
2019
5 Scopus citations

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A brief history of "Alzheimer disease": Multiple meanings separated by a common name

Knopman, D. S., Petersen, R. C. & Jack, C. R. J., May 28 2019, In : Neurology. 92, 22, p. 1053-1059 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR

Schwarz, C., Gunter, J. L., Lowe, V., Weigand, S., Vemuri, P. D., Senjem, M. L., Petersen, R. C., Knopman, D. S. & Jack, C. R. J., Jan 1 2019, In : Journal of Alzheimer's Disease. 67, 1, p. 181-195 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 others, Honig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 2019, In : Neurobiology of aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticle

5 Scopus citations

A Joint Model for Predicting Structural and Functional Brain Health in Elderly Individuals

Varatharajah, Y., Saboo, K., Iyer, R., Przybelski, S., Schwarz, C., Petersen, R., Jack, C. & Vemuri, P., Nov 2019, Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019. Yoo, I., Bi, J. & Hu, X. T. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1657-1664 8 p. 8983291. (Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging

Vemuri, P., Lesnick, T. G., Knopman, D. S., Przybelski, S. A., Reid, R. I., Mielke, M. M., Graff-Radford, J., Lowe, V. J., Machulda, M. M., Petersen, R. C. & Jack, C. R., Jan 1 2019, (Accepted/In press) In : Annals of neurology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2 Scopus citations

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Association Between Critical Care Admissions and Cognitive Trajectories in Older Adults∗

Schulte, P. J., Warner, D. O., Martin, D. P., Deljou, A., Mielke, M. M., Knopman, D. S., Petersen, R. C., Weingarten, T. N., Warner, M. A., Rabinstein, A. A., Hanson, A. C., Schroeder, D. R. & Sprung, J., Aug 1 2019, In : Critical care medicine. 47, 8, p. 1116-1124 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
1 Scopus citations

Association of Longitudinal β-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia

Nedelska, Z., Schwarz, C. G., Lesnick, T. G., Boeve, B. F., Przybelski, S. A., Lowe, V. J., Kremers, W. K., Gunter, J. L., Senjem, M. L., Graff-Radford, J., Ferman, T. J., Fields, J. A., Knopman, D. S., Petersen, R. C., Jack, C. R. & Kantarci, K., Dec 2 2019, In : JAMA Network Open. 2, 12, p. e1916439

Research output: Contribution to journalArticle

Open Access

Association of MAPT Subhaplotypes with Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R. V., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journalArticle

7 Scopus citations

Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Barisch-Fritz, B., Trautwein, S., Boes, K., Woll, A., Kremers, W. K., Machulda, M. M., Mielke, M. M., Knopman, D. S., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : European Journal of Ageing. 16, 4, p. 491-502 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability

Hurtz, S., Chow, N., Watson, A. E., Somme, J. H., Goukasian, N., Hwang, K. S., Morra, J., Elashoff, D., Gao, S., Petersen, R. C., Aisen, P. S., Thompson, P. M. & Apostolova, L. G., 2019, In : NeuroImage: Clinical. 21, 101574.

Research output: Contribution to journalArticle

2 Scopus citations
5 Scopus citations

Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging

Scharf, E. L., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Mielke, M. M., Knopman, D. S., Preboske, G. M., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Machulda, M., Kantarci, K., Petersen, R. C., Jack, C. R. & Vemuri, P., Nov 1 2019, In : Stroke. 50, 11, p. 3037-3044 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cerebral microbleeds: Prevalence and relationship to amyloid burden

Graff-Radford, J., Botha, H., Rabinstein, A., Gunter, J. L., Przybelski, S. A., Lesnick, T., Huston, J., Flemming, K., Preboske, G. M., Senjem, M. L., Brown, R. D. J., Mielke, M. M., Roberts, R. O., Lowe, V., Knopman, D. S., Petersen, R. C., Kremers, W. K., Vemuri, P. D., Jack, C. R. J. & Kantarci, K. M., Jan 15 2019, In : Neurology. 92, 3, p. e253-e262

Research output: Contribution to journalArticle

7 Scopus citations

Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition

Graff-Radford, J., Gunter, J. L., Jones, D. T., Przybelski, S. A., Schwarz, C. G., Huston, J., Lowe, V., Elder, B. D., MacHulda, M. M., Gunter, N. B., Petersen, R. C., Kantarci, K., Vemuri, P., Mielke, M. M., Knopman, D. S., Graff-Radford, N. R. & Jack, C. R., Dec 10 2019, In : Neurology. 93, 24, p. E2237-E2246

Research output: Contribution to journalArticle

Cognitive function after surgery with regional or general anesthesia: A population-based study

Sprung, J., Schulte, P., Knopman, D. S., Mielke, M. M., Petersen, R. C., Weingarten, T. N., Martin, D. P., Hanson, A. C., Schroeder, D. R. & Warner, D. O., Jan 1 2019, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations
1 Scopus citations

Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin

Mielke, M. M., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Vemuri, P., Machulda, M. M., Graff-Radford, J., Knopman, D. S., Jack, C. R., Petersen, R. C. & Kern, S., Nov 2019, In : Alzheimer's and Dementia. 15, 11, p. 1437-1447 11 p.

Research output: Contribution to journalArticle

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Vassilaki, M., Mielke, M. M., Kremers, W. K., Lowe, V. J., Vemuri, P., Machulda, M. M., Christianson, T. J., Syrjanen, J. A., Stokin, G. B., Butler, L. M., Traber, M., Jack, C. R., Knopman, D. S., Roberts, R. O., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : Translational psychiatry. 9, 1, 123.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, V. J., Bruinsma, T. J., Wiste, H. J., Min, H. K., Weigand, S. D., Fang, P., Senjem, M. L., Therneau, T. M., Boeve, B. F., Josephs, K. A., Pandey, M. K., Murray, M. E., Kantarci, K., Jones, D. T., Vemuri, P., Graff-Radford, J., Schwarz, C. G., Machulda, M. M., Mielke, M. M., Roberts, R. O. & 3 others, Knopman, D. S., Petersen, R. C. & Jack, C. R., Jul 2 2019, In : Neurology. 93, 1, p. e29-e39

Research output: Contribution to journalArticle

6 Scopus citations

CSF1R mutation presenting as dementia with Lewy bodies

Sharma, R., Graff-Radford, J., Rademakers, R. V., Boeve, B. F., Petersen, R. C. & Jones, D. T., Jan 1 2019, In : Neurocase.

Research output: Contribution to journalArticle

1 Scopus citations

Deep Learning Prediction of Mild Cognitive Impairment using Electronic Health Records

Fouladvand, S., Mielke, M. M., Vassilaki, M., St Sauver, J., Petersen, R. C. & Sohn, S., Nov 2019, Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019. Yoo, I., Bi, J. & Hu, X. T. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 799-806 8 p. 8982955. (Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology

Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., Parisi, J. E., Lowe, V. J., Petersen, R. C., Kofler, J., Ikonomovic, M. D., López, O., Klunk, W. E., Mayeux, R. P., Frosch, M. P., Wood, L. B. & 1 others, Gomez-Isla, T., Jan 2019, In : Neurobiology of Disease. 121, p. 327-337 11 p.

Research output: Contribution to journalArticle

9 Scopus citations