• 127966 Citations
  • 160 Scopus h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 3869.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
1 Scopus citations

A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 12063.

Research output: Contribution to journalArticle

Open Access

Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific Reports, (2019), 9, 1, (13845), 10.1038/s41598-019-49970-9)

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 10969.

Research output: Contribution to journalComment/debate

Open Access

Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals (Scientific Reports, (2020), 10, 1, (3869), 10.1038/s41598-020-60777-x)

Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 8077.

Research output: Contribution to journalComment/debate

Open Access

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

Arenaza-Urquijo, E. M., Przybelski, S. A., MacHulda, M. M., Knopman, D. S., Lowe, V. J., Mielke, M. M., Reddy, A. L., Geda, Y. E., Jack, C. R., Petersen, R. C. & Vemuri, P., Apr 14 2020, In : Neurology. 94, 15, p. E1571-E1579

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Brain amyloid, cortical thickness, and changes in activities of daily living

Vassilaki, M., Aakre, J. A., Kremers, W. K., Lesnick, T. G., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Butler, L., Traber, M., Vemuri, P., Lowe, V. J., Jack, C. R., Roberts, R. O. & Petersen, R. C., Apr 1 2020, In : Annals of Clinical and Translational Neurology. 7, 4, p. 474-485 12 p.

Research output: Contribution to journalArticle

Open Access

Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele

Ghisays, V., Goradia, D. D., Protas, H., Bauer, R. J., Devadas, V., Tariot, P. N., Lowe, V. J., Knopman, D. S., Petersen, R. C., Jack, C. R., Caselli, R. J., Su, Y., Chen, K. & Reiman, E. M., Apr 1 2020, In : Alzheimer's and Dementia. 16, 4, p. 598-609 12 p.

Research output: Contribution to journalArticle

Cardiorespiratory Fitness and Brain Volumes

Petersen, R. C., Joyner, M. J. & Jack, C. R., Jan 2020, In : Mayo Clinic proceedings. 95, 1, p. 6-8 3 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging

Graff-Radford, J., Lesnick, T., Rabinstein, A. A., Gunter, J., Aakre, J., Przybelski, S. A., Spychalla, A. J., Huston, J., Brown, R. D., Mielke, M. M., Lowe, V. J., Knopman, D. S., Petersen, R. C., Jack, C. R., Vemuri, P., Kremers, W. & Kantarci, K., Jan 14 2020, In : Neurology. 94, 2, p. e190-e199

Research output: Contribution to journalArticle

Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 2975.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity (Acta Neuropathologica, (2019), 138, 2, (237-250), 10.1007/s00401-019-02026-8)

EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group & DESGESCO (Dementia Genetics Spanish Consortium), May 1 2020, In : Acta neuropathologica. 139, 5, p. 959-962 4 p.

Research output: Contribution to journalComment/debate

Open Access
Open Access

Cortical atrophy patterns of incident MCI subtypes in the Mayo Clinic Study of Aging

Machulda, M. M., Lundt, E. S., Albertson, S. M., Spychalla, A. J., Schwarz, C. G., Mielke, M. M., Jack, C. R., Kremers, W. K., Vemuri, P., Knopman, D. S., Jones, D. T., Bondi, M. W. & Petersen, R. C., Jul 1 2020, In : Alzheimer's and Dementia. 16, 7, p. 1013-1022 10 p.

Research output: Contribution to journalArticle

Open Access

CSF biomarkers in Olmsted County: Evidence of 2 subclasses and associations with demographics

Van Harten, A. C., Wiste, H. J., Weigand, S. D., Mielke, M. M., Kremers, W. K., Eichenlaub, U., Batrla-Utermann, R., Dyer, R. B., Algeciras-Schimnich, A., Knopman, D. S., Jack, C. R. & Petersen, R. C., Jul 21 2020, In : Neurology. 95, 3, p. e256-e267

Research output: Contribution to journalArticle

Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes

Buciuc, M., Wennberg, A. M., Weigand, S. D., Murray, M. E., Senjem, M. L., Spychalla, A. J., Boeve, B. F., Knopman, D. S., Jack, C. R., Kantarci, K., Parisi, J. E., Dickson, D. W., Petersen, R. C., Whitwell, J. L. & Josephs, K. A., 2020, In : Journal of Alzheimer's Disease. 73, 4, p. 1511-1523 13 p.

Research output: Contribution to journalArticle

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Exposure to surgery with general anaesthesia during adult life is not associated with increased brain amyloid deposition in older adults

Sprung, J., Warner, D. O., Knopman, D. S., Petersen, R. C., Mielke, M. M., Jack, C. R., Lowe, V. J., Martin, D. P., Hanson, A. C., Schroeder, D. R., Przybelski, S. A., Schulte, P. J., Weingarten, T. N. & Vemuri, P., May 2020, In : British journal of anaesthesia. 124, 5, p. 594-602 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

The Alzheimer Disease Neuroimaging Initiative, Dec 1 2020, In : Nature communications. 11, 1, 411.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2020, In : Nature communications. 11, 1, 347.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology

Nho, K., Nudelman, K., Allen, M., Hodges, A., Kim, S., Risacher, S. L., Apostolova, L. G., Lin, K., Lunnon, K., Wang, X., Burgess, J. D., Ertekin-Taner, N., Petersen, R. C., Wang, L., Qi, Z., He, A., Neuhaus, I., Patel, V., Foroud, T., Faber, K. M. & 4 others, Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 2020, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis

Zeydan, B., Lowe, V. J., Reichard, R. R., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Parisi, J. E., Machulda, M. M., Vemuri, P., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R., Kantarci, O. H. & Kantarci, K., Apr 1 2020, In : Annals of neurology. 87, 4, p. 556-567 12 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

International drive to illuminate delirium: A developing public health blueprint for action

Khachaturian, A. S., Hayden, K. M., Devlin, J. W., Fleisher, L. A., Lock, S. L., Cunningham, C., Oh, E. S., Fong, T. G., Fick, D. M., Marcantonio, E. R., Iyengar, V., Rockwood, K., Kuchel, G. A., Eckenhoff, R. G., MacLullich, A. M. J., Jones, R. N., Davis, D., D'Antonio, P. M., Fargo, K. N., Albert, M. S. & 8 others, Williamson, J. D., Ling, S. M., Weiss, J., Karlawish, J., Petersen, R. C., Blazer, D. G., Khachaturian, Z. S. & Inouye, S. K., May 1 2020, In : Alzheimer's and Dementia. 16, 5, p. 711-725 15 p.

Research output: Contribution to journalArticle

Open Access

Issues and Questions Surrounding Screening for Cognitive Impairment in Older Patients

Petersen, R. C. & Yaffe, K., Feb 25 2020, In : JAMA - Journal of the American Medical Association. 323, 8, p. 722-724 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations
2 Scopus citations

Longitudinal flortaucipir ([18F]AV-1451) PET uptake in semantic dementia

Utianski, R. L., Botha, H., Whitwell, J. L., Martin, P. R., Schwarz, C. G., Duffy, J. R., Clark, H. M., Spychalla, A. J., Senjem, M. L., Petersen, R. C., Knopman, D. S., Jack, C. R., Lowe, V. J. & Josephs, K. A., Aug 2020, In : Neurobiology of aging. 92, p. 135-140 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Medical Doctors and Dementia: A Longitudinal Study

Vassilaki, M., Syrjanen, J. A., Kremers, W. K., Hagen, P. T., Knopman, D. S., Mielke, M. M., Geda, Y. E., Alhurani, R. E., Machulda, M. M., Roberts, R. O. & Petersen, R. C., Jun 1 2020, In : Journal of the American Geriatrics Society. 68, 6, p. 1250-1255 6 p.

Research output: Contribution to journalArticle

Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis

International FTD-Genomics Consortium (IFGC), Dec 1 2020, In : Scientific reports. 10, 1, 12184.

Research output: Contribution to journalArticle

Open Access
Open Access

Pick’s disease: clinicopathologic characterization of 21 cases

Choudhury, P., Scharf, E. L., Paolini, M. A., Graff-Radford, J., Alden, E. C., Machulda, M. M., Jones, D. T., Fields, J. A., Murray, M. E., Graff-Radford, N. R., Constantopoulos, E., Reichard, R. R., Knopman, D. S., Duffy, J. R., Dickson, D. W., Parisi, J. E., Josephs, K. A., Petersen, R. C. & Boeve, B. F., Sep 1 2020, In : Journal of Neurology. 267, 9, p. 2697-2704 8 p.

Research output: Contribution to journalArticle

Preoperative cognitive impairment associated with oversedation during recovery from anesthesia

Kruthiventi, S. C., Laporta, M. L., Deljou, A., Knopman, D. S., Petersen, R. C., Schroeder, D. R., Sprung, J. & Weingarten, T. N., Jun 1 2020, In : Journal of Anesthesia. 34, 3, p. 390-396 7 p.

Research output: Contribution to journalArticle

Prevalence and Heterogeneity of Cerebrovascular Disease Imaging Lesions

Graff-Radford, J., Aakre, J. A., Knopman, D. S., Schwarz, C. G., Flemming, K. D., Rabinstein, A. A., Gunter, J. L., Ward, C. P., Zuk, S. M., Spychalla, A. J., Preboske, G. M., Petersen, R. C., Kantarci, K., Huston, J., Jack, C. R., Mielke, M. M. & Vemuri, P., Jun 2020, In : Mayo Clinic proceedings. 95, 6, p. 1195-1205 11 p.

Research output: Contribution to journalArticle

Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging

Neth, B. J., Graff-Radford, J., Mielke, M. M., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Reid, R. I., Senjem, M. L., Lowe, V. J., Machulda, M. M., Petersen, R. C., Jr, C. R. J., Knopman, D. S. & Vemuri, P., Jan 9 2020, In : Frontiers in Aging Neuroscience. 11, 355.

Research output: Contribution to journalArticle

Open Access

Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution

Ferman, T. J., Aoki, N., Boeve, B. F., Aakre, J. A., Kantarci, K. M., Graff-Radford, J., Parisi, J. E., Van Gerpen, J. A., Graff-Radford, N. R., Uitti, R. J., Pedraza, O., Murray, M. E., Wszolek, Z. K., Reichard, R. R., Fields, J. A., Ross, O. A., Knopman, D. S., Petersen, R. C. & Dickson, D. W., Jul 14 2020, In : Neurology. 95, 2, p. e155-e165

Research output: Contribution to journalArticle

Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease

Liu, C. C., Yamazaki, Y., Heckman, M. G., Martens, Y. A., Jia, L., Yamazaki, A., Diehl, N. N., Zhao, J., Zhao, N., DeTure, M., Davis, M. D., Felton, L. M., Qiao, W., Li, Y., Li, H., Fu, Y., Wang, N., Wren, M., Aikawa, T., Holm, M. L. & 10 others, Oue, H., Linares, C., Allen, M., Carrasquillo, M. M., Murray, M. E., Petersen, R. C., Ertekin-Taner, N., Dickson, D. W., Kanekiyo, T. & Bu, G., 2020, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Open Access

Tau-positron emission tomography correlates with neuropathology findings

Lowe, V. J., Lundt, E. S., Albertson, S. M., Min, H. K., Fang, P., Przybelski, S. A., Senjem, M. L., Schwarz, C. G., Kantarci, K., Boeve, B., Jones, D. T., Reichard, R. R., Tranovich, J. F., Hanna Al-Shaikh, F. S., Knopman, D. S., Jack, C. R., Dickson, D. W., Petersen, R. C. & Murray, M. E., Mar 1 2020, In : Alzheimer's and Dementia. 16, 3, p. 561-571 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

The quest for dementia prevention does not include an aspirin a day

Knopman, D. S. & Petersen, R. C., Jul 21 2020, In : Neurology. 95, 3, p. 105-106 2 p.

Research output: Contribution to journalEditorial

Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy

Buciuc, M., Botha, H., Murray, M. E., Schwarz, C. G., Senjem, M. L., Jones, D. T., Knopman, D. S., Boeve, B. F., Petersen, R. C., Jack, C. R., Petrucelli, L., Parisi, J. E., Dickson, D. W., Lowe, V., Whitwell, J. L. & Josephs, K. A., Jul 7 2020, In : Neurology. 95, 1, p. e23-e34

Research output: Contribution to journalArticle

Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderly

Carvalho, D. Z., StLouis, E. K., Schwarz, C. G., Lowe, V. J., Boeve, B. F., Przybelski, S. A., Reddy, A., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R. & Vemuri, P., Apr 28 2020, In : Neurology. 94, 17, p. E1793-E1802

Research output: Contribution to journalArticle

1 Scopus citations

β-Amyloid PET and neuropathology in dementia with Lewy bodies

Kantarci, K., Lowe, V. J., Chen, Q., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Jack, C. R., Graff-Radford, J., Jones, D. T., Knopman, D. S., Graff-Radford, N., Ferman, T. J., Parisi, J. E., Dickson, D. W., Petersen, R. C., Boeve, B. F. & Murray, M. E., Jan 21 2020, In : Neurology. 94, 3, p. e282-e291

Research output: Contribution to journalArticle

Open Access