• 117463 Citations
  • 153 Scopus h-Index
1974 …2020
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Research Output 1974 2020

2015
31 Citations (Scopus)

Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging

Knopman, D. S., Beiser, A., Machulda, M. M., Fields, J. A., Roberts, R. O., Pankratz, V. S., Aakre, J., Cha, R. H., Rocca, W. A., Mielke, M. M., Boeve, B. F., Devine, S., Ivnik, R. J., Au, R., Auerbach, S., Wolf, P. A., Seshadri, S. & Petersen, R. C., Nov 10 2015, In : Neurology. 85, 19, p. 1712-1721 10 p.

Research output: Contribution to journalArticle

Cognition
Dementia
Neuropsychological Tests
Consensus
Population
133 Citations (Scopus)

Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies

Rabin, L. A., Smart, C. M., Crane, P. K., Amariglio, R. E., Berman, L. M., Boada, M., Buckley, R. F., Chételat, G., Dubois, B., Ellis, K. A., Gifford, K. A., Jefferson, A. L., Jessen, F., Katz, M. J., Lipton, R. B., Luck, T., Maruff, P., Mielke, M. M., Molinuevo, J. L., Naeem, F. & 18 others, Perrotin, A., Petersen, R. C., Rami, L., Reisberg, B., Rentz, D. M., Riedel-Heller, S. G., Risacher, S. L., Rodriguez, O., Sachdev, P. S., Saykin, A. J., Slavin, M. J., Snitz, B. E., Sperling, R. A., Tandetnik, C., Van Der Flier, W. M., Wagner, M., Wolfsgruber, S. & Sikkes, S. A. M., Sep 24 2015, In : Journal of Alzheimer's Disease. 48, S1, p. S63-S86

Research output: Contribution to journalArticle

Self Report
Research
Cognitive Dysfunction
Executive Function
Names
2 Citations (Scopus)

Subjective cognitive impairment et maladie d'Alzheimer: Étude d'une cohorte de 51 sujets suivis sur deux ans

Translated title of the contribution: Subjective cognitive impairment and Alzheimer's disease: A two year follow up of 51 subjects during two yearsSambuchi, N., Muraccioli, I., Alescio-Lautier, BÉ., Paban, VÉ., Sambuc, R., Jouve, É., Geda, Y. E., Petersen, R. C. & Michel, B. F., Dec 1 2015, In : Geriatrie et Psychologie Neuropsychiatrie du Vieillissement. 13, 4, p. 462-471 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Cognitive Dysfunction
Atrophy
Episodic Memory
Executive Function
33 Citations (Scopus)

TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

Josephs, K. A., Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Murray, M. E., Liesinger, A. M., Petrucelli, L., Senjem, M. L., Ivnik, R. J., Parisi, J. E., Petersen, R. C. & Dickson, D. W., Nov 1 2015, In : Annals of Neurology. 78, 5, p. 697-709 13 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Alzheimer Disease
Pathology
Neurofibrillary Tangles
Memory Disorders
30 Citations (Scopus)

The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans

Kang, J. H., Korecka, M., Figurski, M. J., Toledo, J. B., Blennow, K., Zetterberg, H., Waligorska, T., Brylska, M., Fields, L., Shah, N., Soares, H., Dean, R. A., Vanderstichele, H., Petersen, R. C., Aisen, P. S., Saykin, A. J., Weiner, M. W., Trojanowski, J. Q. & Shaw, L. M., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 772-791 20 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Biomarkers
Cerebrospinal Fluid
Prodromal Symptoms
5 Citations (Scopus)

The human Alzheimer disease project: A new call to arms

Rosenberg, R. N. & Petersen, R. C., Jun 1 2015, In : JAMA Neurology. 72, 6, p. 626-628 3 p.

Research output: Contribution to journalArticle

Alzheimer Disease
64 Citations (Scopus)
Amyloid
Longitudinal Studies
Dementia
Cohort Studies
Biomarkers
113 Citations (Scopus)

Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Preboske, G. M., Kantarci, K. M., Raman, M. R., Machulda, M. M., Mielke, M. M., Lowe, V., Senjem, M. L., Gunter, J. L., Rocca, W. A., Roberts, R. O., Petersen, R. C. & Jack, C. R. J., Mar 1 2015, In : Brain : a journal of neurology. 138, p. 761-771 11 p.

Research output: Contribution to journalArticle

Amyloid
Blood Vessels
Pathology
Cognitive Reserve
Positron-Emission Tomography
17 Citations (Scopus)

White matter integrity in dementia with Lewy bodies: A voxel-based analysis of diffusion tensor imaging

Nedelska, Z., Schwarz, C., Boeve, B. F., Lowe, V., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Gunter, J. L., Senjem, M. L., Ferman, T. J., Smith, G. E., Geda, Y. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Jun 1 2015, In : Neurobiology of Aging. 36, 6, p. 2010-2017 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Diffusion Tensor Imaging
Alzheimer Disease
Glucose
Amyloid
141 Citations (Scopus)

Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease

Pottier, C., Bieniek, K. F., Finch, N. C., van de Vorst, M., Baker, M., Perkersen, R., Brown, P., Ravenscroft, T., Van Blitterswijk, M., Nicholson, A. M., Deture, M., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Boylan, K. B., Boeve, B. F., Graff Radford, N. R., Veltman, J. A., Gilissen, C. & 3 others, Murray, M. E., Dickson, D. W. & Rademakers, R. V., May 6 2015, In : Acta Neuropathologica. 130, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Motor Neuron Disease
DNA-Binding Proteins
Phosphotransferases
Genome
38 Citations (Scopus)

Working memory and language network dysfunctions in logopenic aphasia: A task-free fMRI comparison with Alzheimer's dementia

Whitwell, J. L., Jones, D. T., Duffy, J. R., Strand, E. A., Machulda, M. M., Przybelski, S. A., Vemuri, P. D., Gregg, B. E., Gunter, J. L., Senjem, M. L., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., Mar 1 2015, In : Neurobiology of Aging. 36, 3, p. 1245-1252 8 p.

Research output: Contribution to journalArticle

Aphasia
Short-Term Memory
Alzheimer Disease
Language
Magnetic Resonance Imaging
2016
63 Citations (Scopus)

[18F]AV-1451 tau positron emission tomography in progressive supranuclear palsy

Whitwell, J. L., Lowe, V., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Schwarz, C., Spychalla, A. J., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., 2016, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Positron-Emission Tomography
Alzheimer Disease
Globus Pallidus
Tauopathies
290 Citations (Scopus)

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

Jack, C. R. J., Bennett, D. A., Blennow, K., Carrillo, M. C., Feldman, H. H., Frisoni, G. B., Hampel, H., Jagust, W. J., Johnson, K. A., Knopman, D. S., Petersen, R. C., Scheltens, P., Sperling, R. A. & Dubois, B., Aug 2 2016, In : Neurology. 87, 5, p. 539-547 9 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Biomarkers
Amyloid
Fluorodeoxyglucose F18
Research
11 Citations (Scopus)

ABCA7 loss-of-function variants, expression, and neurologic disease risk

Allen, M., Lincoln, S. J., Corda, M., Watzlawik, J. O., Carrasquillo, M. M., Reddy, J. S., Burgess, J. D., Nguyen, T., Malphrus, K., Petersen, R. C., Graff Radford, N. R., Dickson, D. W. & Taner, N., Jan 1 2016, In : Neurology: Genetics. 3, 1, e126.

Research output: Contribution to journalArticle

Nervous System Diseases
Adenosine Triphosphate
Alzheimer Disease
Messenger RNA
Proteins
19 Citations (Scopus)

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Carrasquillo, M. M., Allen, M., Burgess, J. D., Wang, X., Strickland, S. L., Aryal, S., Siuda, J., Kachadoorian, M. L., Medway, C., Younkin, C. S., Nair, A., Wang, C., Chanana, P., Serie, D., Nguyen, T., Lincoln, S., Malphrus, K. G., Morgan, K., Golde, T. E., Price, N. D. & 10 others, White, C. C., De Jager, P. L., Bennett, D. A., Asmann, Y., Crook, J., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Multigene Family
Alzheimer Disease
Quantitative Trait Loci
Gene Expression
Meta-Analysis
14 Citations (Scopus)

Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Aug 16 2016, In : Neurology. 87, 7, p. 691-698 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Fluorodeoxyglucose F18
Amyloid
Research Design
52 Citations (Scopus)

A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

Schwarz, C., Gunter, J. L., Wiste, H. J., Przybelski, S. A., Weigand, S. D., Ward, C. P., Senjem, M. L., Vemuri, P. D., Murray, M. E., Dickson, D. W., Parisi, J. E., Kantarci, K. M., Weiner, M. W., Petersen, R. C. & Jack, C. R. J., 2016, In : NeuroImage: Clinical. 11, p. 802-812 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Neurofibrillary Tangles
Head
Autopsy
Parietal Lobe
33 Citations (Scopus)

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 1 2016, In : PLoS One. 11, 2, e0148717.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
28 Citations (Scopus)

Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies

Sarro, L., Senjem, M. L., Lundt, E. S., Przybelski, S. A., Lesnick, T. G., Graff-Radford, J., Boeve, B. F., Lowe, V., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Oct 1 2016, In : Brain. 139, 10, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Amyloid
Atrophy
Magnetic Resonance Imaging
Positron-Emission Tomography
177 Citations (Scopus)
DNA-Binding Proteins
Tauopathies
Neurofibrillary Tangles
Dementia
Alzheimer Disease
12 Citations (Scopus)

An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease

Sarro, L., Tosakulwong, N., Schwarz, C., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Zuk, S. M., Reid, R. I., Raman, M. R., Boeve, B. F., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Murray, M. E., Parisi, J. E., Dickson, D. W., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Vascular Diseases
Cardiovascular Diseases
White Matter
80 Citations (Scopus)

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 97 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carrasquillo, M. M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D. & Petersen, R. C., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
20 Citations (Scopus)

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
91 Citations (Scopus)

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition
Atrophy
Brain
Neuroimaging
98 Citations (Scopus)

Association between olfactory dysfunction and amnestic mild cognitive impairment and Alzheimer disease dementia

Roberts, R. O., Christianson, T. J. H., Kremers, W. K., Mielke, M. M., Machulda, M. M., Vassilaki, M., Alhurani, R. E., Geda, Y. E., Knopman, D. S. & Petersen, R. C., Jan 1 2016, In : JAMA Neurology. 73, 1, p. 93-101 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Smell
Cognitive Dysfunction
Lost to Follow-Up
Cognition
74 Citations (Scopus)

Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community

Petersen, R. C., Wiste, H. J., Weigand, S. D., Rocca, W. A., Roberts, R. O., Mielke, M. M., Lowe, V., Knopman, D. S., Pankratz, V. S., Machulda, M. M., Geda, Y. E. & Jack, C. R. J., Jan 1 2016, In : JAMA Neurology. 73, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Amyloid
Cognition
Biomarkers
Positron-Emission Tomography
Alzheimer Disease
28 Citations (Scopus)

Association of Mild Cognitive Impairment With Exposure to General Anesthesia for Surgical and Nonsurgical Procedures: A Population-Based Study

Sprung, J., Roberts, R. O., Knopman, D. S., Olive, D. M., Gappa, J. L., Sifuentes, V. L., Behrend, T. L., Farmer, J. D., Weingarten, T. N., Hanson, A. C., Schroeder, D. R., Petersen, R. C. & Warner, D. O., Feb 1 2016, In : Mayo Clinic Proceedings. 91, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

General Anesthesia
Population
Anesthesia
Cognitive Dysfunction
Nervous System
59 Citations (Scopus)

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

Kantarci, K. M., Lowe, V., Boeve, B. F., Senjem, M. L., Tosakulwong, N., Lesnick, T. G., Spychalla, A. J., Gunter, J. L., Fields, J. A., Graff-Radford, J., Ferman, T. J., Jones, D. T., Murray, M. E., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., 2016, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

Lewy Body Disease
Amyloid
Positron-Emission Tomography
Alzheimer Disease
Occipital Lobe
72 Citations (Scopus)

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Williams, K. L., Topp, S., Yang, S., Smith, B., Fifita, J. A., Warraich, S. T., Zhang, K. Y., Farrawell, N., Vance, C., Hu, X., Chesi, A., Leblond, C. S., Lee, A., Rayner, S. L., Sundaramoorthy, V., Dobson-Stone, C., Molloy, M. P., Van Blitterswijk, M., Dickson, D. W., Petersen, R. C. & 48 others, Graff Radford, N. R., Boeve, B. F., Murray, M. E., Pottier, C., Don, E., Winnick, C., McCann, E. P., Hogan, A., Daoud, H., Levert, A., Dion, P. A., Mitsui, J., Ishiura, H., Takahashi, Y., Goto, J., Kost, J., Gellera, C., Gkazi, A. S., Miller, J., Stockton, J., Brooks, W. S., Boundy, K., Polak, M., Muñoz-Blanco, J. L., Esteban-Pérez, J., Rábano, A., Hardiman, O., Morrison, K. E., Ticozzi, N., Silani, V., De Belleroche, J., Glass, J. D., Kwok, J. B. J., Guillemin, G. J., Chung, R. S., Tsuji, S., Brown, R. H., García-Redondo, A., Rademakers, R. V., Landers, J. E., Gitler, A. D., Rouleau, G. A., Cole, N. J., Yerbury, J. J., Atkin, J. D., Shaw, C. E., Nicholson, G. A. & Blair, I. P., Apr 15 2016, In : Nature Communications. 7, 11253.

Research output: Contribution to journalArticle

Ubiquitinated Proteins
mutations
Ubiquitin-Protein Ligase Complexes
proteins
Mutation
17 Citations (Scopus)

Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging

Wennberg, A. M. V., Savica, R., Hagen, C. E., Roberts, R. O., Knopman, D. S., Hollman, J. H., Vemuri, P. D., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., 2016, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Gait
Amyloid
Gyrus Cinguli
Linear Models
Normal Pressure Hydrocephalus
14 Citations (Scopus)

Characterizing white matter tract degeneration in syndromic variants of Alzheimer's disease: A diffusion tensor imaging study

Madhavan, A., Schwarz, C., Duffy, J. R., Strand, E. A., Machulda, M. M., Drubach, D., Kantarci, K. M., Przybelski, S. A., Reid, R. I., Senjem, M. L., Gunter, J. L., Apostolova, L. G., Lowe, V., Petersen, R. C., Jack, C. R. J., Josephs, K. A. & Whitwell, J. L., 2016, In : Journal of Alzheimer's Disease. 49, 3, p. 633-643 11 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Alzheimer Disease
Atrophy
Corpus Callosum
Primary Progressive Aphasia
35 Citations (Scopus)

Chronic depressive symptomatology in mild cognitive impairment is associated with frontal atrophy rate which hastens conversion to Alzheimer dementia

Sacuiu, S., Insel, P. S., Mueller, S., Tosun, D., Mattsson, N., Jack, C. R. J., DeCarli, C., Petersen, R. C., Aisen, P. S., Weiner, M. W. & Scott MacKin, R., Feb 1 2016, In : American Journal of Geriatric Psychiatry. 24, 2, p. 126-135 10 p.

Research output: Contribution to journalArticle

Atrophy
Alzheimer Disease
Depression
Cognitive Dysfunction
Gyrus Cinguli

Corrigendum to “Genome-wide association interaction analysis for Alzheimer's disease.” [Neurobiol. Aging (2014) 35 (2436–2443)] (S0197458014003777)(10.1016/j.neurobiolaging.2014.05.014)

Gusareva, E. S., Carrasquillo, M. M., Bellenguez, C., Cuyvers, E., Colon, S., Graff Radford, N. R., Petersen, R. C., Dickson, D. W., Mahachie John, J. M., Bessonov, K., Van Broeckhoven, C., Ramirez, A., Harold, D., Williams, J., Amouyel, P., Sleegers, K., Taner, N., Lambert, J. C. & Van Steen, K., Jan 1 2016, In : Neurobiology of Aging. 37, p. 211 1 p.

Research output: Contribution to journalComment/debate

Genome-Wide Association Study
Germany
Psychiatry
Alzheimer Disease
corrigendum
26 Citations (Scopus)

Decline in weight and incident mild cognitive impairment Mayo Clinic study of aging

Alhurani, R. E., Vassilaki, M., Aakre, J. A., Mielke, M. M., Kremers, W. K., Machulda, M. M., Geda, Y. E., Knopman, D. S., Petersen, R. C. & Roberts, R. O., Apr 1 2016, In : JAMA Neurology. 73, 4, p. 439-446 8 p.

Research output: Contribution to journalArticle

Weights and Measures
Dementia
Body Mass Index
Medical Record Linkage
Prodromal Symptoms
118 Citations (Scopus)

Defining imaging biomarker cut points for brain aging and Alzheimer's disease

Jack, C. R. J., Wiste, H. J., Weigand, S. D., Therneau, T. M., Lowe, V., Knopman, D. S., Gunter, J. L., Senjem, M. L., Jones, D. T., Kantarci, K. M., Machulda, M. M., Mielke, M. M., Roberts, R. O., Vemuri, P. D., Reyes, D. A. & Petersen, R. C., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Brain Diseases
Positron-Emission Tomography
Alzheimer Disease
Biomarkers
Deoxyglucose
237 Citations (Scopus)

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature Communications. 7, 11934.

Research output: Contribution to journalArticle

Blood Vessels
Alzheimer Disease
Biomarkers
biomarkers
Disease Progression
37 Citations (Scopus)

Effect of intellectual enrichment on AD biomarker trajectories

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Machulda, M. M., Lowe, V., Mielke, M. M., Roberts, R. O., Gunter, J. L., Senjem, M. L., Geda, Y. E., Rocca, W. A., Petersen, R. C. & Jack, C. R. J., Mar 22 2016, In : Neurology. 86, 12, p. 1128-1135 8 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Biomarkers
Exercise
Occupations
7 Citations (Scopus)

Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum

Knopman, D. S., Jack, C. R. J., Lundt, E. S., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Oct 1 2016, In : Neurobiology of Aging. 46, p. 32-42 11 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Biomarkers
Positron-Emission Tomography
Parietal Lobe
21 Citations (Scopus)
Fatigue
Brain
Linear Models
Temporal Lobe
Atrophy
15 Citations (Scopus)

FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging

Krell-Roesch, J., Ruider, H., Lowe, V., Stokin, G. B., Pink, A., Roberts, R. O., Mielke, M. M., Knopman, D. S., Christianson, T. J., Machulda, M. M., Jack, C. R. J., Petersen, R. C. & Geda, Y. E., 2016, In : Journal of Alzheimer's Disease. 53, 4, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

Asymptomatic Diseases
Equipment and Supplies
Alzheimer Disease
Odds Ratio
Depression
9 Citations (Scopus)

First PET imaging studies with 63Zn-zinc citrate in healthy human participants and patients with Alzheimer disease

DeGrado, T. R., Kemp, B. J., Pandey, M., Jiang, H., Gunderson, T. M., Linscheid, L. R., Woodwick, A. R., McConnell, D. M., Fletcher, J. G., Johnson, G. B., Petersen, R. C., Knopman, D. S. & Lowe, V., 2016, In : Molecular Imaging. 15, p. 1-10 10 p.

Research output: Contribution to journalArticle

Positron emission tomography
citrates
Citric Acid
Positron-Emission Tomography
Zinc
18 Citations (Scopus)

Frailty and Mortality Outcomes in Cognitively Normal Older People: Sex Differences in a Population-Based Study

Bartley, M. M., Geda, Y. E., Christianson, T. J. H., Shane Pankratz, V., Roberts, R. O. & Petersen, R. C., Jan 1 2016, In : Journal of the American Geriatrics Society. 64, 1, p. 132-137 6 p.

Research output: Contribution to journalArticle

Sex Characteristics
Mortality
Confidence Intervals
Population
Proportional Hazards Models
5 Citations (Scopus)

FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G

Tacik, P., Deture, M., Carlomagno, Y., Lin, W. L., Murray, M. E., Baker, M. C., Josephs, K. A., Boeve, B. F., Wszolek, Z. K., Graff Radford, N. R., Parisi, J. E., Petrucelli, L., Rademakers, R. V., Isaacson, R. S., Heilman, K. M., Petersen, R. C., Dickson, D. W. & Kouri, N., 2016, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Inclusion Bodies
Mutation
Microtubule-Associated Proteins
Exons
27 Citations (Scopus)

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Schott, J. M., Crutch, S. J., Carrasquillo, M. M., Uphill, J., Shakespeare, T. J., Ryan, N. S., Yong, K. X., Lehmann, M., Taner, N., Graff Radford, N. R., Boeve, B. F., Murray, M. E., Khan, Q. U. A., Petersen, R. C., Dickson, D. W., Knopman, D. S., Rabinovici, G. D., Miller, B. L., González, A. S., Gil-Néciga, E. & 24 others, Snowden, J. S., Harris, J., Pickering-Brown, S. M., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Pijnenburg, Y. A., Galasko, D., Sarazin, M., Dubois, B., Magnin, E., Galimberti, D., Scarpini, E., Cappa, S. F., Hodges, J. R., Halliday, G. M., Bartley, L., Carrillo, M. C., Bras, J. T., Hardy, J., Rossor, M. N., Collinge, J., Fox, N. C. & Mead, S., Aug 1 2016, In : Alzheimer's and Dementia. 12, 8, p. 862-871 10 p.

Research output: Contribution to journalArticle

Atrophy
Alzheimer Disease
Odds Ratio
Genome-Wide Association Study
2 Citations (Scopus)

Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC Genomics. 17, 436.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prolactin
Cerebrospinal Fluid
Immune System Phenomena
Single Nucleotide Polymorphism
16 Citations (Scopus)

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment

Kantarci, K. M., Lesnick, T., Ferman, T. J., Przybelski, S. A., Boeve, B. F., Smith, G. E., Kremers, W. K., Knopman, D. S., Jack, C. R. J. & Petersen, R. C., Nov 29 2016, In : Neurology. 87, 22, p. 2317-2323 7 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Atrophy
Cognitive Dysfunction
36 Citations (Scopus)

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Allen, M., Carrasquillo, M. M., Funk, C., Heavner, B. D., Zou, F., Younkin, C. S., Burgess, J. D., Chai, H. S., Crook, J., Eddy, J. A., Li, H., Logsdon, B., Peters, M. A., Dang, K. K., Wang, X., Serie, D., Wang, C., Nguyen, T., Lincoln, S., Malphrus, K. & 11 others, Bisceglio, G., Li, M., Golde, T. E., Mangravite, L. M., Asmann, Y., Price, N. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Oct 11 2016, In : Scientific data. 3, 160089.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Genotype
Brain
Genome
Genes
24 Citations (Scopus)

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

Shinohara, M., Murray, M. E., Frank, R. D., Shinohara, M., Deture, M., Yamazaki, Y., Tachibana, M., Atagi, Y., Davis, M. D., Liu, C-C., Zhao, N., Painter, M. M., Petersen, R. C., Fryer, J. D., Crook, J., Dickson, D. W., Bu, G. D. & Kanekiyo, T., May 14 2016, (Accepted/In press) In : Acta Neuropathologica. p. 1-10 10 p.

Research output: Contribution to journalArticle

Cerebral Amyloid Angiopathy
Alzheimer Disease
Apolipoproteins E
Temporal Lobe
Amyloid
9 Citations (Scopus)

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

Informatics
Computational Biology
Endophenotypes
Cerebrospinal Fluid
Alzheimer Disease
33 Citations (Scopus)

Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort

Dage, J. L., Wennberg, A. M. V., Airey, D. C., Hagen, C. E., Knopman, D. S., Machulda, M. M., Roberts, R. O., Jack, C. R. J., Petersen, R. C. & Mielke, M. M., Dec 1 2016, In : Alzheimer's and Dementia. 12, 12, p. 1226-1234 9 p.

Research output: Contribution to journalArticle

tau Proteins
Cognition
Population
Positron-Emission Tomography
Alzheimer Disease