• 4503 Citations
  • 35 Scopus h-Index
1987 …2019
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Research Output 1987 2019

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Review article
2019

Assessing and Counseling the Older Driver: A Concise Review for the Generalist Clinician

Hill, L. J. N., Pignolo, R. & Tung, E. E., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1582-1588 7 p.

Research output: Contribution to journalReview article

Open Access
Counseling
Cognition
Habits
Comorbidity
Referral and Consultation
7 Citations (Scopus)

Exceptional Human Longevity

Pignolo, R., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 110-124 15 p.

Research output: Contribution to journalReview article

Health Promotion
Biomarkers
Geography
Disease Resistance
Age of Onset
3 Citations (Scopus)

Targeting Cell Senescence for the Treatment of Age-Related Bone Loss

Pignolo, R., Samsonraj, R. M., Law, S. F., Wang, H. & Chandra, A., Apr 15 2019, In : Current Osteoporosis Reports. 17, 2, p. 70-85 16 p.

Research output: Contribution to journalReview article

Cell Aging
Osteoporosis
Bone and Bones
Phenotype
Osteocytes
2017
4 Citations (Scopus)

International physician survey on management of FOP: A modified Delphi study

Di Rocco, M., Baujat, G., Bertamino, M., Brown, M., De Cunto, C. L., Delai, P. L. R., Eekhoff, E. M. W., Haga, N., Hsiao, E., Keen, R., Morhart, R., Pignolo, R. & Kaplan, F. S., Jun 12 2017, In : Orphanet Journal of Rare Diseases. 12, 1, 110.

Research output: Contribution to journalReview article

Myositis Ossificans
Delphi Technique
Physicians
Type I Activin Receptors
Consensus
2016
32 Citations (Scopus)

Granting immunity to FOP and catching heterotopic ossification in the Act

Kaplan, F. S., Pignolo, R. & Shore, E. M., Jan 1 2016, In : Seminars in Cell and Developmental Biology. 49, p. 30-36 7 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Heterotopic Ossification
Immunity
Osteogenesis
Bone Morphogenetic Proteins
2015
34 Citations (Scopus)

Progressive osseous heteroplasia: Diagnosis, treatment, and prognosis

Pignolo, R., Ramaswamy, G., Fong, J. T., Shore, E. M. & Kaplan, F. S., Jan 15 2015, In : Application of Clinical Genetics. 8, p. 37-48 12 p.

Research output: Contribution to journalReview article

Pseudohypoparathyroidism
GTP-Binding Protein alpha Subunits
Heterotopic Ossification
Mutation
Inborn Genetic Diseases
31 Citations (Scopus)

The Immunological Contribution to Heterotopic Ossification Disorders

Convente, M. R., Wang, H., Pignolo, R., Kaplan, F. S. & Shore, E. M., Jan 1 2015, In : Current Osteoporosis Reports. 13, 2, p. 116-124 9 p.

Research output: Contribution to journalReview article

Heterotopic Ossification
Immune System
Osteogenesis
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Disease Management
2013
68 Citations (Scopus)

Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons.

Pignolo, R., Shore, E. M. & Kaplan, F. S., Jun 1 2013, In : Pediatric endocrinology reviews : PER. 10 Suppl 2, p. 437-448 12 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Heterotopic Ossification
Osteogenesis
Type I Bone Morphogenetic Protein Receptors
Therapeutics
24 Citations (Scopus)

From mysteries to medicines: Drug development for fibrodysplasia ossificans progressiva

Kaplan, F. S., Pignolo, R. & Shore, E. M., Jan 1 2013, In : Expert Opinion on Orphan Drugs. 1, 8, p. 637-649 13 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Pharmaceutical Preparations
Type I Activin Receptors
Type I Bone Morphogenetic Protein Receptors
Activin Receptors
2011
62 Citations (Scopus)

Circulating osteogenic cells: Implications for injury, repair, and regeneration

Pignolo, R. & Kassem, M., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1685-1693 9 p.

Research output: Contribution to journalReview article

Regeneration
Wounds and Injuries
Osteogenesis
Reading
115 Citations (Scopus)

Fibrodysplasia ossificans progressiva: Clinical and genetic aspects

Pignolo, R., Shore, E. M. & Kaplan, F. S., Dec 2 2011, In : Orphanet Journal of Rare Diseases. 6, 1, 80.

Research output: Contribution to journalReview article

Myositis Ossificans
Hallux
Aggressive Fibromatosis
Heterotopic Ossification
Virus Diseases
2009
41 Citations (Scopus)

The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling

Kaplan, F. S., Pignolo, R. & Shore, E. M., Oct 1 2009, In : Cytokine and Growth Factor Reviews. 20, 5-6, p. 399-407 9 p.

Research output: Contribution to journalReview article

Type I Bone Morphogenetic Protein Receptors
Myositis Ossificans
Tissue
Bone Morphogenetic Protein Receptors
Heterotopic Ossification
2008
184 Citations (Scopus)

Fibrodysplasia ossificans progressiva

Kaplan, F. S., Le Merrer, M., Glaser, D. L., Pignolo, R., Goldsby, R. E., Kitterman, J. A., Groppe, J. & Shore, E. M., Mar 1 2008, In : Best Practice and Research: Clinical Rheumatology. 22, 1, p. 191-205 15 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Heterotopic Ossification
Type I Bone Morphogenetic Protein Receptors
Activin Receptors
Soft Tissue Injuries
50 Citations (Scopus)

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

Kaplan, F. S., Shen, Q., Lounev, V., Seemann, P., Groppe, J., Katagiri, T., Pignolo, R. & Shore, E. M., Nov 1 2008, In : Journal of Bone and Mineral Metabolism. 26, 6, p. 521-530 10 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Type I Bone Morphogenetic Protein Receptors
Activin Receptors
Biological Phenomena
Activins
2007
37 Citations (Scopus)

A new era for fibrodysplasia ossificans progressiva: A druggable target for the second skeleton

Kaplan, F. S., Glaser, D. L., Pignolo, R. & Shore, E. M., May 1 2007, In : Expert Opinion on Biological Therapy. 7, 5, p. 705-712 8 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Activins
Skeleton
Phosphotransferases
Type I Bone Morphogenetic Protein Receptors
2005
32 Citations (Scopus)

Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway

Kaplan, F. S., Shore, E. M., Gupta, R., Billings, P. C., Glaser, D. L., Pignolo, R., Graf, D. & Kamoun, M., Sep 1 2005, In : Clinical Reviews in Bone and Mineral Metabolism. 3, 3-4, p. 189-193 5 p.

Research output: Contribution to journalReview article

Myositis Ossificans
Bone and Bones
Immune System
Proteins
1998
35 Citations (Scopus)

The pathway of cell senescence: WI-38 cells arrest in late G1 and are unable to traverse the cell cycle from a true G0 state

Pignolo, R., Martin, B. G., Horton, J. H., Kalbach, A. N. & Cristofalo, V. J., Jan 1 1998, In : Experimental Gerontology. 33, 1-2, p. 67-80 14 p.

Research output: Contribution to journalReview article

Cell Aging
Cell Cycle
Cells
Fibroblasts
DNA
1994
31 Citations (Scopus)

Molecular biology of aging

Cristofalo, V. J., Gerhard, G. S. & Pignolo, R., Jan 1 1994, In : Surgical Clinics of North America. 74, 1, p. 1-21 21 p.

Research output: Contribution to journalReview article

Molecular Biology
Biological Phenomena
Cell Aging
Quality of Life
1993
223 Citations (Scopus)

Replicative senescence of human fibroblast-like cells in culture

Cristofalo, V. J. & Pignolo, R., Jan 1 1993, In : Physiological Reviews. 73, 3, p. 617-638 22 p.

Research output: Contribution to journalReview article

Cell Aging
Cell Division
Cultured Cells
Cell Culture Techniques
Fibroblasts