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1980 …2019
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Research Output 1986 2019

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Article
2013
29 Citations (Scopus)

Comparison of fluorescence in situ hybridization (FISH) and dual-ISH (DISH) in the determination of her2 status in breast cancer

Mansfield, A., Sukov, W. R., Eckel-Passow, J. E., Sakai, Y., Walsh, F. J., Lonzo, M., Wiktor, A. E., Dogan, A. & Jenkins, R. B., Feb 2013, In : American Journal of Clinical Pathology. 139, 2, p. 144-150 7 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Breast Neoplasms
Centromere
Confidence Intervals
Chromosomes, Human, Pair 17
29 Citations (Scopus)

Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: A molecular subclass of rectal cancer

Boardman, L. A., Johnson, R. A., Viker, K. B., Hafner, K. A., Jenkins, R. B., Riegert-Johnson, D. L., Smyrk, T. C., Litzelman, K., Seo, S., Gangnon, R. E., Engelman, C. D., Rider, D. N., Vanderboom, R. J., Thibodeau, S. N., Petersen, G. M. & Skinner, H. G., Nov 21 2013, In : PLoS One. 8, 11, e80015.

Research output: Contribution to journalArticle

Telomere Homeostasis
Chromosomal Instability
telomeres
Telomere
Rectal Neoplasms
22 Citations (Scopus)

Description of selected characteristics of familial glioma patients-Results from the Gliogene Consortium

Sadetzki, S., Bruchim, R., Oberman, B., Armstrong, G. N., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Il'Yasova, D., Schildkraut, J., Johansen, C., Houlston, R. S., Shete, S., Amos, C. I., Bernstein, J. L., Olson, S. H., Jenkins, R. B., Lachance, D. H., Vick, N. A., Merrell, R., Wrensch, M. & 5 others, Davis, F. G., McCarthy, B. J., Lai, R., Melin, B. S. & Bondy, M. L., Apr 2013, In : European Journal of Cancer. 49, 6, p. 1335-1345 11 p.

Research output: Contribution to journalArticle

Glioma
Glioblastoma
Demography
Oligodendroglioma
Neurofibromatoses
280 Citations (Scopus)

Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy

Erho, N., Crisan, A., Vergara, I. A., Mitra, A. P., Ghadessi, M., Buerki, C., Bergstralh, E. J., Kollmeyer, T., Fink, S., Haddad, Z., Zimmermann, B., Sierocinski, T., Ballman, K. V., Triche, T. J., Black, P. C., Karnes, R. J., Klee, G., Davicioni, E. & Jenkins, R. B., Jun 24 2013, In : PLoS One. 8, 6, e66855.

Research output: Contribution to journalArticle

prostatic neoplasms
Prostatectomy
metastasis
Prostatic Neoplasms
Classifiers
2 Citations (Scopus)

Erratum: Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology (Journal of Thoracic Oncology (2013) 8 (823-859))

Lindeman, N. I., Cagle, P. T., Beasley, M. B., Chitale, D. A., Dacic, S., Giaccone, G., Jenkins, R. B., Kwiatkowski, D. J., Saldivar, J. S., Squire, J., Thunnissen, E. & Ladanyi, M., 2013, In : Journal of Thoracic Oncology. 8, 10, p. 1343 1 p.

Research output: Contribution to journalArticle

Molecular Pathology
Protein-Tyrosine Kinases
Lung Neoplasms
Thorax
Guidelines
20 Citations (Scopus)

Genetics in glioma: Lessons learned from genome-wide association studies

Melin, B. & Jenkins, R. B., Dec 2013, In : Current Opinion in Neurology. 26, 6, p. 688-692 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Glioma
Genetic Loci
Neoplasms
Therapeutics
32 Citations (Scopus)

Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: Evidence for distinct pathways of gliomagenesis

Walsh, K. M., Rice, T., Decker, P. A., Kosel, M. L., Kollmeyer, T., Hansen, H. M., Zheng, S., McCoy, L. S., Bracci, P. M., Anderson, E., Hsuang, G., Wiemels, J. L., Pico, A. R., Smirnov, I., Molinaro, A. M., Tihan, T., Berger, M. S., Chang, S. M., Prados, M. D., Lachance, D. H. & 5 others, Sicotte, H., Eckel-Passow, J. E., Wiencke, J. K., Jenkins, R. B. & Wrensch, M. R., Aug 2013, In : Neuro-Oncology. 15, 8, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

Telomerase
Glioma
Genes
Single Nucleotide Polymorphism
Alleles
65 Citations (Scopus)

Immunohistochemistry and fluorescence in situ hybridization assessment of HER2 in clinical trials of adjuvant therapy for breast cancer (NCCTG N9831, BCIRG 006, and BCIRG 005)

Perez, E. A., Press, M. F., Dueck, A., Jenkins, R. B., Kim, C., Chen, B., Villalobos, I., Paik, S., Buyse, M., Wiktor, A. E., Meyer, R., Finnigan, M., Zujewski, J., Shing, M., Stern, H. M., Lingle, W. L., Reinholz, M. M. & Slamon, D. J., 2013, In : Breast Cancer Research and Treatment. 138, 1, p. 99-108 10 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Immunohistochemistry
Clinical Trials
Breast Neoplasms
Therapeutics
14 Citations (Scopus)

Impact of c-MYC protein expression on outcome of patients with early-stage HER2+ breast cancer treated with adjuvant trastuzumab NCCTG (Alliance) N9831

Dueck, A., Reinholz, M. M., Geiger, X. J., Tenner, K., Ballman, K., Jenkins, R. B., Riehle, D., Chen, B., McCullough, A. E., Davidson, N. E., Martino, S., Sledge, G. W., Kaufman, P. A., Kutteh, L. A., Gralow, J., Harris, L. N., Ingle, J. N., Lingle, W. L. & Perez, E. A., Oct 15 2013, In : Clinical Cancer Research. 19, 20, p. 5798-5807 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasms
Proteins
Disease-Free Survival
Drug Therapy
82 Citations (Scopus)

Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial.

Perez, E. A., Dueck, A., McCullough, A. E., Chen, B., Geiger, X. J., Jenkins, R. B., Lingle, W. L., Davidson, N. E., Martino, S., Kaufman, P. A., Kutteh, L. A., Sledge, G. W., Harris, L. N., Gralow, J. R. & Reinholz, M. M., Jun 10 2013, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31, 17, p. 2115-2122 8 p.

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Breast Neoplasms
Neoplasms
Disease-Free Survival
Therapeutics
31 Citations (Scopus)

Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology

Rice, T., Zheng, S., Decker, P. A., Walsh, K. M., Bracci, P., Xiao, Y., McCoy, L. S., Smirnov, I., Patoka, J. S., Hansen, H. M., Hsuang, G., Wiemels, J. L., Tihan, T., Pico, A. R., Prados, M. D., Chang, S. M., Berger, M. S., Caron, A., Fink, S., Kollmeyer, T. & 12 others, Rynearson, A., Voss, J., Kosel, M. L., Fridley, B. L., Lachance, D. H., Eckel-Passow, J. E., Sicotte, H., O'Neill, B. P., Giannini, C., Wiencke, J. K., Jenkins, R. B. & Wrensch, M. R., May 2013, In : Neuro-Oncology. 15, 5, p. 535-541 7 p.

Research output: Contribution to journalArticle

Glioma
Histology
Chromosomes
Glioblastoma
Alleles
313 Citations (Scopus)

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the college of american pathologists, international association for the study of lung cancer, and association for molecular pathology

Lindeman, N. I., Cagle, P. T., Beasley, M. B., Chitale, D. A., Dacic, S., Giaccone, G., Jenkins, R. B., Kwiatkowski, D. J., Saldivar, J. S., Squire, J., Thunnissen, E. & Ladanyi, M., Jul 2013, In : Journal of Molecular Diagnostics. 15, 4, p. 415-453 39 p.

Research output: Contribution to journalArticle

Molecular Pathology
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Lung Neoplasms
Guidelines
285 Citations (Scopus)

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the study of lung cancer, and Association for Molecular Pathology

Lindeman, N. I., Cagle, P. T., Beasley, M. B., Chitale, D. A., Dacic, S., Giaccone, G., Jenkins, R. B., Kwiatkowski, D. J., Saldivar, J. S., Squire, J., Thunnissen, E. & Ladanyi, M., Jun 2013, In : Archives of Pathology and Laboratory Medicine. 137, 6, p. 828-860 33 p.

Research output: Contribution to journalArticle

Molecular Pathology
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Lung Neoplasms
Guidelines
509 Citations (Scopus)

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology

Lindeman, N. I., Cagle, P. T., Beasley, M. B., Chitale, D. A., Dacic, S., Giaccone, G., Jenkins, R. B., Kwiatkowski, D. J., Saldivar, J. S., Squire, J., Thunnissen, E. & Ladanyi, M., Jul 2013, In : Journal of Thoracic Oncology. 8, 7, p. 823-859 37 p.

Research output: Contribution to journalArticle

Molecular Pathology
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Lung Neoplasms
Guidelines
544 Citations (Scopus)

Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: Long-term results of RTOG 9402

Cairncross, G., Wang, M., Shaw, E., Jenkins, R. B., Brachman, D., Buckner, J. C., Fink, K., Souhami, L., Laperriere, N., Curran, W. & Mehta, M., Jan 20 2013, In : Journal of Clinical Oncology. 31, 3, p. 337-343 7 p.

Research output: Contribution to journalArticle

Oligodendroglioma
Chemoradiotherapy
Lomustine
Procarbazine
Radiotherapy
12 Citations (Scopus)

RC0639: Phase II study of paclitaxel, trastuzumab, and lapatinib as adjuvant therapy for early stage HER2-positive breast cancer

Moreno Aspitia, A., Dueck, A., Ghanem-Cañete, I., Patel, T., Dakhil, S., Johnson, D., Franco, S., Kahanic, S., Colon-Otero, G., Tenner, K. S., Rodeheffer, R., McCullough, A. E., Jenkins, R. B., Palmieri, F. M., Northfelt, D. W. & Perez, E. A., Apr 2013, In : Breast Cancer Research and Treatment. 138, 2, p. 427-435 9 p.

Research output: Contribution to journalArticle

Paclitaxel
Breast Neoplasms
Therapeutics
Heart Failure
Safety
1894 Citations (Scopus)

Recommendations for human epidermal growth factor receptor 2 testing in breast

Wolff, A. C., Hammond, M. E. H., Hicks, D. G., Dowsett, M., McShane, L. M., Allison, K. H., Allred, D. C., Bartlett, J. M. S., Bilous, M., Fitzgibbons, P., Hanna, W., Jenkins, R. B., Mangu, P. B., Paik, S., Perez, E. A., Press, M. F., Spears, P. A., Vance, G. H., Viale, G. & Hayes, D. F., Nov 1 2013, In : Journal of Clinical Oncology. 31, 31, p. 3997-4013 17 p.

Research output: Contribution to journalArticle

Breast
In Situ Hybridization
Immunohistochemistry
Guidelines
Breast Neoplasms
301 Citations (Scopus)

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

Chan, K. M., Fang, D., Gan, H., Hashizume, R., Yu, C., Schroeder, M., Gupta, N., Mueller, S., David James, C., Jenkins, R. B., Sarkaria, J. N. & Zhang, Z., May 1 2013, In : Genes and Development. 27, 9, p. 985-990 6 p.

Research output: Contribution to journalArticle

Glioma
Histones
Methylation
Pediatrics
Gene Expression
367 Citations (Scopus)

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

Prensner, J. R., Iyer, M. K., Sahu, A., Asangani, I. A., Cao, Q., Patel, L., Vergara, I. A., Davicioni, E., Erho, N., Ghadessi, M., Jenkins, R. B., Triche, T. J., Malik, R., Bedenis, R., McGregor, N., Ma, T., Chen, W., Han, S., Jing, X., Cao, X. & 9 others, Wang, X., Chandler, B., Yan, W., Siddiqui, J., Kunju, L. P., Dhanasekaran, S. M., Pienta, K. J., Feng, F. Y. & Chinnaiyan, A. M., Nov 2013, In : Nature Genetics. 45, 11, p. 1392-1403 12 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Prostatic Neoplasms
Neoplasm Metastasis
Neoplasms
Chromatin
186 Citations (Scopus)

Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk Patient population

Karnes, R. J., Bergstralh, E. J., Davicioni, E., Ghadessi, M., Buerki, C., Mitra, A. P., Crisan, A., Erho, N., Vergara, I. A., Lam, L. L., Carlson, R., Thompson, D. J. S., Haddad, Z., Zimmermann, B., Sierocinski, T., Triche, T. J., Kollmeyer, T., Ballman, K. V., Black, P. C., Klee, G. G. & 1 others, Jenkins, R. B., Dec 2013, In : Journal of Urology. 190, 6, p. 2047-2053 7 p.

Research output: Contribution to journalArticle

Prostatectomy
Neoplasm Metastasis
Prostatic Neoplasms
Nomograms
Validation Studies
2012
8 Citations (Scopus)

A cytogenetic analysis of 2 cases of phosphaturic mesenchymal tumor of mixed connective tissue type

Graham, R., Hodge, J. C., Folpe, A. L., Oliveira, A. M., Meyer, K. J., Jenkins, R. B., Sim, F. H. & Sukov, W. R., Aug 2012, In : Human Pathology. 43, 8, p. 1334-1338 5 p.

Research output: Contribution to journalArticle

Cytogenetic Analysis
Connective Tissue
Neoplasms
Abnormal Karyotype
Karyotype
54 Citations (Scopus)

Adverse prognostic impact of intratumor heterogeneous HER2 gene amplification in patients with esophageal adenocarcinoma

Yoon, H. H., Shi, Q. D., Sukov, W. R., Lewis, M. A., Sattler, C. A., Wiktor, A. E., Wu, T. T., Diasio, R. B., Jenkins, R. B. & Sinicrope, F. A., Nov 10 2012, In : Journal of Clinical Oncology. 30, 32, p. 3932-3938 7 p.

Research output: Contribution to journalArticle

erbB-2 Genes
Gene Amplification
Adenocarcinoma
Survival
Neoplasms
83 Citations (Scopus)

A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation

Jenkins, R. B., Xiao, Y., Sicotte, H., Decker, P. A., Kollmeyer, T. M., Hansen, H. M., Kosel, M. L., Zheng, S., Walsh, K. M., Rice, T., Bracci, P., McCoy, L. S., Smirnov, I., Patoka, J. S., Hsuang, G., Wiemels, J. L., Tihan, T., Pico, A. R., Prados, M. D., Chang, S. M. & 13 others, Berger, M. S., Caron, A. A., Fink, S. R., Halder, C., Rynearson, A. L., Fridley, B. L., Buckner, J. C., O'Neill, B. P., Giannini, C., Lachance, D. H., Wiencke, J. K., Eckel-Passow, J. E. & Wrensch, M. R., Oct 2012, In : Nature Genetics. 44, 10, p. 1122-1125 4 p.

Research output: Contribution to journalArticle

Astrocytoma
Single Nucleotide Polymorphism
Mutation
Glioma
Neoplasms
87 Citations (Scopus)

Association of HER2/ErbB2 expression and gene amplification with pathologic features and prognosis in esophageal adenocarcinomas

Yoon, H. H., Shi, Q. D., Sukov, W. R., Wiktor, A. E., Khan, M., Sattler, C. A., Grothey, A. F., Wu, T. T., Diasio, R. B., Jenkins, R. B. & Sinicrope, F. A., Jan 15 2012, In : Clinical Cancer Research. 18, 2, p. 546-554 9 p.

Research output: Contribution to journalArticle

erbB-2 Genes
Barrett Esophagus
Gene Amplification
Adenocarcinoma
Survival
13 Citations (Scopus)

A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma

Sun, X., Vengoechea, J., Elston, R., Chen, Y., Amos, C. I., Armstrong, G., Bernstein, J. L., Claus, E., Davis, F., Houlston, R. S., Il'yasova, D., Jenkins, R. B., Johansen, C., Lai, R., Lau, C. C., Liu, Y., McCarthy, B. J., Olson, S. H., Sadetzki, S., Schildkraut, J. & 9 others, Shete, S., Yu, R., Vick, N. A., Merrell, R., Wrensch, M., Yang, P., Melin, B., Bondy, M. L. & Barnholtz-Sloan, J. S., Dec 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 12, p. 2242-2251 10 p.

Research output: Contribution to journalArticle

Pedigree
Age of Onset
Glioma
Gene Frequency
Chromosomes, Human, Pair 17
4 Citations (Scopus)

Differential distribution of CCDC26 glioma-risk alleles in myeloid malignancies with mutant IDH1 compared with their IDH2R140-mutated or IDH-unmutated counterparts

Lasho, T. L., Tefferi, A., Pardanani, A. D., Finke, C. M., Fink, S. R., Caron, A. A., Decker, P. A. & Jenkins, R. B., Jun 2012, In : Leukemia. 26, 6, p. 1406-1407 2 p.

Research output: Contribution to journalArticle

Intracellular Signaling Peptides and Proteins
Isocitrate Dehydrogenase
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Acute Myeloid Leukemia
Glioma
385 Citations (Scopus)

Genetics of adult glioma

Goodenberger, M. L. & Jenkins, R. B., Dec 2012, In : Cancer genetics. 205, 12, p. 613-621 9 p.

Research output: Contribution to journalArticle

Glioma
Histology
Hereditary Neoplastic Syndromes
Oligodendroglioma
Central Nervous System Neoplasms
154 Citations (Scopus)

Genome-wide association study of glioma and meta-analysis

Rajaraman, P., Melin, B. S., Wang, Z., McKean-Cowdin, R., Michaud, D. S., Wang, S. S., Bondy, M., Houlston, R., Jenkins, R. B., Wrensch, M., Yeager, M., Ahlbom, A., Albanes, D., Andersson, U., Freeman, L. E. B., Buring, J. E., Butler, M. A., Braganza, M., Carreon, T., Feychting, M. & 50 others, Fleming, S. J., Gapstur, S. M., Gaziano, J. M., Giles, G. G., Hallmans, G., Henriksson, R., Hoffman-Bolton, J., Inskip, P. D., Johansen, C., Kitahara, C. M., Lathrop, M., Liu, C., Marchand, L. L., Linet, M. S., Lonn, S., Peters, U., Purdue, M. P., Rothman, N., Ruder, A. M., Sanson, M., Sesso, H. D., Severi, G., Shu, G., Simon, M., Stampfer, M., Stevens, V. L., Visvanathan, K., White, E., Wolk, A., Zeleniuch-Jacquotte, A., Zheng, W., Decker, P., Enciso-Mora, V., Fridley, B., Gao, Y. T., Kosel, M., Lachance, D. H., Lau, C., Rice, T., Swerdlow, A., Wiemels, J. L., Wiencke, J. K., Shete, S., Xiang, Y. B., Xiao, Y., Hoover, R. N., Fraumeni, J. F., Chatterjee, N., Hartge, P. & Chanock, S. J., Dec 2012, In : Human Genetics. 131, 12, p. 1877-1888 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Glioma
Meta-Analysis
Cohort Studies
Case-Control Studies
13 Citations (Scopus)

Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma

Liu, Y., Melin, B. S., Rajaraman, P., Wang, Z., Linet, M., Shete, S., Amos, C. I., Lau, C. C., Scheurer, M. E., Tsavachidis, S., Armstrong, G. N., Houlston, R. S., Hosking, F. J., Claus, E. B., Barnholtz-Sloan, J., Lai, R., Il'yasova, D., Schildkraut, J., Sadetzki, S., Johansen, C. & 12 others, Bernstein, J. L., Olson, S. H., Jenkins, R. B., La Chance, D., Vick, N. A., Wrensch, M., Davis, F., McCarthy, B. J., Andersson, U., Thompson, P. A., Chanock, S. & Bondy, M. L., Sep 2012, In : Human Genetics. 131, 9, p. 1507-1517 11 p.

Research output: Contribution to journalArticle

Glioma
Single Nucleotide Polymorphism
Brain Neoplasms
Genotype
Gene Dosage
8 Citations (Scopus)

Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: A novel candidate SNP approach

Jacobs, D. I., Walsh, K. M., Wrensch, M., Wiencke, J., Jenkins, R. B., Houlston, R. S., Bondy, M., Simon, M., Sanson, M., Gousias, K., Schramm, J., Labussière, M., Di Stefano, A. L., Wichmann, H. E., Müller-Nurasyid, M., Schreiber, S., Franke, A., Moebus, S., Eisele, L., Dewan, A. T. & 1 others, Dubrow, R., 2012, In : Frontiers in Genetics. 3, OCT, Article 203.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Ethnic Groups
Glioma
Single Nucleotide Polymorphism
Incidence
49 Citations (Scopus)

MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors

Singhi, A. D., Cimino-Mathews, A., Jenkins, R. B., Lan, F., Fink, S. R., Nassar, H., Vang, R., Fetting, J. H., Hicks, J., Sukumar, S., De Marzo, A. M. & Argani, P., Mar 2012, In : Modern Pathology. 25, 3, p. 378-387 10 p.

Research output: Contribution to journalArticle

Gene Amplification
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Autopsy
86 Citations (Scopus)

P16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

Cen, L., Carlson, B. L., Schroeder, M. A., Ostrem, J. L., Kitange, G. J., Mladek, A. C., Fink, S. R., Decker, P. A., Wu, W., Kim, J. S., Waldman, T., Jenkins, R. B. & Sarkaria, J. N., Jul 2012, In : Neuro-Oncology. 14, 7, p. 870-881 12 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Glioblastoma
Heterografts
Cell Proliferation
Survival
15 Citations (Scopus)

Phase i study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors

Bryce, A. H., Rao, R., Sarkaria, J. N., Reid, J. M., Qi, Y., Qin, R., James, C. D., Jenkins, R. B., Boni, J., Erlichman, C. & Haluska, P., Oct 2012, In : Investigational New Drugs. 30, 5, p. 1934-1941 8 p.

Research output: Contribution to journalArticle

Maximum Tolerated Dose
Pharmacokinetics
Nausea
Diarrhea
Neoplasms
62 Citations (Scopus)

Predictability of adjuvant trastuzumab benefit in N9831 patients using the ASCO/CAP HER2-positivity criteria

Perez, E. A., Dueck, A., McCullough, A. E., Reinholz, M. M., Tenner, K. S., Davidson, N. E., Gralow, J., Harris, L. N., Kutteh, L. A., Hillman, D. W., Jenkins, R. B. & Chen, B., Jan 18 2012, In : Journal of the National Cancer Institute. 104, 2, p. 159-162 4 p.

Research output: Contribution to journalArticle

Medical Oncology
United States Food and Drug Administration
Disease-Free Survival
Fluorescence In Situ Hybridization
Immunohistochemistry
1 Citation (Scopus)

Rare and uncommon genetic variants may hold key to the 'missing heritability' in glioma

Egan, K. M., Wrensch, M. R. & Jenkins, R. B., Nov 1 2012, In : CNS oncology. 1, 2, p. 109-112 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Resolving the breakpoints of the 17q21.31 microdeletion syndrome with next-generation sequencing

Itsara, A., Vissers, L. E. L. M., Steinberg, K. M., Meyer, K. J., Zody, M. C., Koolen, D. A., De Ligt, J., Cuppen, E., Baker, C., Lee, C., Graves, T. A., Wilson, R. K., Jenkins, R. B., Veltman, J. A. & Eichler, E. E., Apr 6 2012, In : American Journal of Human Genetics. 90, 4, p. 599-613 15 p.

Research output: Contribution to journalArticle

Genomic Segmental Duplications
Genome
Haplotypes
Comparative Genomic Hybridization
Hybrid Cells
31 Citations (Scopus)

Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome

Hurley, P. J., Marchionni, L., Simons, B. W., Ross, A. E., Peskoe, S. B., Miller, R. M., Erho, N., Vergara, I. A., Ghadessi, M., Huang, Z., Gurel, B., Park, B. H., Davicioni, E., Jenkins, R. B., Platz, E. A., Berman, D. M. & Schaeffer, E. M., Sep 11 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 37, p. 14977-14982 6 p.

Research output: Contribution to journalArticle

Cysteine
Prostatic Neoplasms
Proteins
Recurrence
Prostate
13 Citations (Scopus)

SSBP2 variants are associated with survival in glioblastoma patients

Xiao, Y., Decker, P. A., Rice, T., McCoy, L. S., Smirnov, I., Patoka, J. S., Hansen, H. M., Wiemels, J. L., Tihan, T., Prados, M. D., Chang, S. M., Berger, M. S., Kosel, M. L., Fridley, B. L., Lachance, D. H., O'Neill, B. P., Buckner, J. C., Thompson, R. C., Nabors, L. B., Olson, J. J. & 7 others, Brem, S., Madden, M. H., Browning, J. E., Wiencke, J. K., Egan, K. M., Jenkins, R. B. & Wrensch, M. R., Jun 1 2012, In : Clinical Cancer Research. 18, 11, p. 3154-3162 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Single Nucleotide Polymorphism
Survival
Proteins
temozolomide
2011
33 Citations (Scopus)

A carrier for non-covalent delivery of functional beta-galactosidase and antibodies against amyloid plaques and IgM to the brain

Sarkar, G., Curran, G. L., Mahlum, E., Decklever, T., Wengenack, T. M., Blahnik, A., Hoesley, B., Lowe, V., Poduslo, J. F. & Jenkins, R. B., Dec 21 2011, In : PLoS One. 6, 12, e28881.

Research output: Contribution to journalArticle

Amyloid Plaques
amyloid
beta-Galactosidase
beta-galactosidase
Amyloid
150 Citations (Scopus)

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

Stacey, S. N., Sulem, P., Jonasdottir, A., Masson, G., Gudmundsson, J., Gudbjartsson, D. F., Magnusson, O. T., Gudjonsson, S. A., Sigurgeirsson, B., Thorisdottir, K., Ragnarsson, R., Benediktsdottir, K. R., Nexø, B. A., Tjønneland, A., Overvad, K., Rudnai, P., Gurzau, E., Koppova, K., Hemminki, K., Corredera, C. & 83 others, Fuentelsaz, V., Grasa, P., Navarrete, S., Fuertes, F., García-Prats, M. D., Sanambrosio, E., Panadero, A., De Juan, A., Garcia, A., Rivera, F., Planelles, D., Soriano, V., Requena, C., Aben, K. K., Van Rossum, M. M., Cremers, R. G. H. M., Van Oort, I. M., Van Spronsen, D. J., Schalken, J. A., Peters, W. H. M., Helfand, B. T., Donovan, J. L., Hamdy, F. C., Badescu, D., Codreanu, O., Jinga, M., Csiki, I. E., Constantinescu, V., Badea, P., Mates, I. N., Dinu, D. E., Constantin, A., Mates, D., Kristjansdottir, S., Agnarsson, B. A., Jonsson, E., Barkardottir, R. B., Einarsson, G. V., Sigurdsson, F., Moller, P. H., Stefansson, T., Valdimarsson, T., Johannsson, O. T., Sigurdsson, H., Jonsson, T., Jonasson, J. G., Tryggvadottir, L., Rice, T., Hansen, H. M., Xiao, Y., Lachance, D. H., O'Neill, B. P., Kosel, M. L., Decker, P. A., Thorleifsson, G., Johannsdottir, H., Helgadottir, H. T., Sigurdsson, A., Steinthorsdottir, V., Lindblom, A., Sandler, R. S., Keku, T. O., Banasik, K., Jørgensen, T., Witte, D. R., Hansen, T., Pedersen, O., Jinga, V., Neal, D. E., Catalona, W. J., Wrensch, M., Wiencke, J., Jenkins, R. B., Nagore, E., Vogel, U., Kiemeney, L. A., Kumar, R., Mayordomo, J. I., Olafsson, J. H., Kong, A., Thorsteinsdottir, U., Rafnar, T. & Stefansson, K., Nov 2011, In : Nature Genetics. 43, 11, p. 1098-1103 6 p.

Research output: Contribution to journalArticle

Polyadenylation
Odds Ratio
Neoplasms
Single Nucleotide Polymorphism
Li-Fraumeni Syndrome
43 Citations (Scopus)

Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking

Lachance, D. H., Yang, P., Johnson, D. R., Decker, P. A., Kollmeyer, T. M., McCoy, L. S., Rice, T., Xiao, Y., Ali-Osman, F., Wang, F., Stoddard, S. M., Sprau, D. J., Kosel, M. L., Wiencke, J. K., Wiemels, J. L., Patoka, J. S., Davis, F., McCarthy, B., Rynearson, A. L., Worra, J. B. & 6 others, Fridley, B. L., O'Neill, B. P., Buckner, J. C., Il'Yasova, D., Jenkins, R. B. & Wrensch, M. R., Sep 1 2011, In : American Journal of Epidemiology. 174, 5, p. 574-581 8 p.

Research output: Contribution to journalArticle

Glioma
Hypersensitivity
Smoking
Alleles
Confidence Intervals
45 Citations (Scopus)

C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the North Central Cancer Treatment Group N9831 adjuvant trastuzumab trial

Perez, E. A., Jenkins, R. B., Dueck, A., Wiktor, A. E., Bedroske, P. P., Anderson, S. K., Ketterling, R. P., Sukov, W. R., Kanehira, K., Chen, B., Geiger, X. J., Andorfer, C. A., McCullough, A. E., Davidson, N. E., Martino, S., Sledge, G. W., Kaufman, P. A., Kutteh, L. A., Gralow, J. R., Harris, L. N. & 3 others, Ingle, J. N., Lingle, W. L. & Reinholz, M. M., Feb 20 2011, In : Journal of Clinical Oncology. 29, 6, p. 651-659 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Chromosomes, Human, Pair 8
Neoplasms
Disease-Free Survival
Therapeutics
62 Citations (Scopus)

Distinct germ line polymorphisms underlie glioma morphologic heterogeneity

Jenkins, R. B., Wrensch, M. R., Johnson, D., Fridley, B. L., Decker, P. A., Xiao, Y., Kollmeyer, T. M., Rynearson, A. L., Fink, S., Rice, T., McCoy, L. S., Halder, C., Kosel, M. L., Giannini, C., Tihan, T., O'Neill, B. P., Lachance, D. H., Yang, P., Wiemels, J. & Wiencke, J. K., Jan 2011, In : Cancer genetics. 204, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

Germ Cells
Glioma
Single Nucleotide Polymorphism
Odds Ratio
Glioblastoma
32 Citations (Scopus)

Genome-wide high-density SNP linkage search for glioma susceptibility loci: Results from the gliogene consortium

Shete, S., Lau, C. C., Houlston, R. S., Claus, E. B., Barnholtz-Sloan, J., Lai, R., Il'yasova, D., Schildkraut, J., Sadetzki, S., Johansen, C., Bernstein, J. L., Olson, S. H., Jenkins, R. B., Yang, P., Vick, N. A., Wrensch, M., Davis, F. G., McCarthy, B. J., Leung, E. H. C., Davis, C. & 39 others, Cheng, R., Hosking, F. J., Armstrong, G. N., Liu, Y., Yu, R. K., Henriksson, R., Melin, B. S., Bondy, M. L., Amos, C., Aldape, K. D., Gilbert, M. R., Weinberg, J., Man, C., Guerra, R., Gurusiddappa, S., Scheurer, M. E., Robertson, L., Papaemmanuil, E., Sloan, A. E., Barnett, G., Devine, K., Wolinsky, Y., Florendo, E., Rivas, D., Corpuz, C., Yechezkel, G. H., Bruchim, R. B. S., Aslanov, L., Bødtcher, H., Kosteljanetz, M., Broholm, H., Schubert, E., DeAngelis, L., Rynearson, A., Andersson, U., Brännström, T., Wiencke, J., Wiemels, J. & McCoy, L., Dec 15 2011, In : Cancer Research. 71, 24, p. 7568-7575 8 p.

Research output: Contribution to journalArticle

Glioma
Single Nucleotide Polymorphism
Genome
Genetic Heterogeneity
Molecular Epidemiology
21 Citations (Scopus)

Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development

Brisbin, A. G., Asmann, Y., Song, H., Tsai, Y. Y., Aakre, J. A., Yang, P., Jenkins, R. B., Pharoah, P., Schumacher, F., Conti, D. V., Duggan, D. J., Jenkins, M., Hopper, J., Gallinger, S., Newcomb, P., Casey, G., Sellers, T. A. & Fridley, B. L., Dec 5 2011, In : BMC Medical Genetics. 12, 156.

Research output: Contribution to journalArticle

Meta-Analysis
Single Nucleotide Polymorphism
Neoplasms
Prostatic Neoplasms
Genes
5 Citations (Scopus)

Oligodendroglial tumors with marked desmoplasia: Clinicopathologic and molecular features of 7 cases

Jentoft, M., Giannini, C., Rossi, S., Mota, R., Jenkins, R. B. & Rodriguez, F. J., Jun 2011, In : American Journal of Surgical Pathology. 35, 6, p. 845-852 8 p.

Research output: Contribution to journalArticle

Neoplasms
Oligodendroglioma
Mutation
Mitotic Index
Mutant Proteins
183 Citations (Scopus)

Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer

Perez, E. A., Suman, V. J., Davidson, N. E., Gralow, J. R., Kaufman, P. A., Visscher, D. W., Chen, B., Ingle, J. N., Dakhil, S. R., Zujewski, J., Moreno Aspitia, A., Pisansky, T. M. & Jenkins, R. B., Dec 1 2011, In : Journal of Clinical Oncology. 29, 34, p. 4491-4497 7 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Breast Neoplasms
Disease-Free Survival
Paclitaxel
Survival Rate
52 Citations (Scopus)

Transformation of low grade glioma and correlation with outcome: An NCCTG database analysis

Jaeckle, K. A., Decker, P. A., Ballman, K. V., Flynn, P. J., Giannini, C., Scheithauer, B. W., Jenkins, R. B. & Buckner, J. C., Aug 2011, In : Journal of Neuro-Oncology. 104, 1, p. 253-259 7 p.

Research output: Contribution to journalArticle

Glioma
Glioblastoma
Databases
Recurrence
Astrocytoma
2010
11 Citations (Scopus)

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

D'Assoro, A., Leontovich, A., Amato, A., Ayers-Ringler, J. R., Quatraro, C., Hafner, K., Jenkins, R. B., Libra, M., Ingle, J., Stivala, F., Galanis, E. & Salisbury, J. L., Nov 2010, In : International Journal of Oncology. 37, 5, p. 1167-1176 10 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Epithelial-Mesenchymal Transition
Transcriptome
Heterografts
Breast Neoplasms
243 Citations (Scopus)

A multigene predictor of outcome in glioblastoma

Colman, H., Zhang, L., Sulman, E. P., McDonald, J. M., Shooshtari, N. L., Rivera, A., Popoff, S., Nutt, C. L., Louis, D. N., Cairncross, J. G., Gilbert, M. R., Phillips, H. S., Mehta, M. P., Chakravarti, A., Pelloski, C. E., Bhat, K., Feuerstein, B. G., Jenkins, R. B. & Aldape, K., Jan 2010, In : Neuro-Oncology. 12, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Genes
Paraffin
Formaldehyde
Therapeutics