Robert Brian Jenkins, MD, PhD &ndash; Research Output

2016

Approaching a scientific consensus on the association between allergies and glioma risk: A report from the glioma international case-control study

Amirian, E. S., Zhou, R., Wrensch, M. R., Olson, S. H., Scheurer, M. E., Il'Yasova, D., Lachance, D. H., Armstrong, G. N., Mccoy, L. S., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Johansen, C., Houlston, R. S., Jenkins, R. B., Bernstein, J. L., Merrell, R. T. & 6 others, Davis, F. G., Lai, R., Shete, S., Amos, C. I., Melin, B. S. & Bondy, M. L., Feb 1 2016, In : Cancer Epidemiology Biomarkers and Prevention. 25, 2, p. 282-290 9 p.

Research output: Contribution to journal › Article

Glioma

Case-Control Studies

Hypersensitivity

Eczema

Asthma

7 Citations (Scopus)

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth

Hu, B. R., Fairey, A. S., Madhav, A., Yang, D., Li, M., Groshen, S., Stephens, C., Kim, P. H., Virk, N., Wang, L., Martin, S. E., Erho, N., Davicioni, E., Jenkins, R. B., Den, R. B., Xu, T., Xu, Y., Gill, I. S., Quinn, D. I. & Goldkorn, A., May 1 2016, In : Prostate. 76, 6, p. 597-608 12 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Recurrence

Growth

Neoplasms

Prostatectomy

4 Citations (Scopus)

Central nervous system relapse in patients with untreated HER2-positive esophageal or gastroesophageal junction adenocarcinoma

Yoon, H. H., Lewis, M. A., Foster, N. R., Sukov, W. R., Khan, M., Sattler, C. A., Wiktor, A. E., Wu, T. T., Jenkins, R. B. & Sinicrope, F. A., Oct 1 2016, In : International Journal of Cancer. 139, 7, p. 1626-1631 6 p.

Research output: Contribution to journal › Article

Esophagogastric Junction

Adenocarcinoma

Central Nervous System

Recurrence

Neoplasms

38 Citations (Scopus)

Change in pattern of HER2 fluorescent in situ hybridization (FISH) results in breast cancers submitted for FISH testing: Experience of a reference laboratory using US Food and Drug Administration criteria and American Society of Clinical Oncology and College of American Pathologists guidelines

Shah, M. V., Wiktor, A. E., Meyer, R. G., Tenner, K. S., Ballman, K. V., Green, S. J., Sukov, W. R., Ketterling, R. P., Perez, E. A. & Jenkins, R. B., Oct 10 2016, In : Journal of Clinical Oncology. 34, 29, p. 3502-3510 9 p.

Research output: Contribution to journal › Article

United States Food and Drug Administration

Fluorescence In Situ Hybridization

Guidelines

Breast Neoplasms

Immunohistochemistry

30 Citations (Scopus)

Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma

Gupta, S. K., Kizilbash, S., Carlson, B. L., Mladek, A. C., Boakye-Agyeman, F., Bakken, K. K., Pokorny, J. L., Schroeder, M. A., Decker, P. A., Cen, L., Eckel-Passow, J. E., Sarkar, G., Ballman, K. V., Reid, J. M., Jenkins, R. B., Verhaak, R. G., Sulman, E. P., Kitange, G. J. & Sarkaria, J. N., May 1 2016, In : Journal of the National Cancer Institute. 108, 5, djv369.

Research output: Contribution to journal › Article

temozolomide

Methyltransferases

Glioblastoma

Biomarkers

Heterografts

9 Citations (Scopus)

History of chickenpox in glioma risk: a report from the glioma international case–control study (GICC)

Amirian, E. S., Scheurer, M. E., Zhou, R., Wrensch, M. R., Armstrong, GN., Lachance, D. H., Olson, S. H., Lau, C. C., Claus, E. B., Barnholtz-Sloan, JS., Il'yasova, D., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Jenkins, R. B., Bernstein, J. L., Merrell, R. T., Davis, F. G., Lai, R., Shete, S. & 3 others, Amos, C. I., Melin, B. S. & Bondy, M. L., Jun 1 2016, In : Cancer Medicine. 5, 6, p. 1352-1358 7 p.

Research output: Contribution to journal › Article

Chickenpox

Glioma

Human Herpesvirus 3

Cranial Nerves

Herpesviridae

9 Citations (Scopus)

Impact of RNA degradation on fusion detection by RNA-seq

Davila, J. I., Fadra, N. M., Wang, X., McDonald, A. M., Nair, A. A., Crusan, B. R., Wu, X., Blommel, J. H., Jen, J., Rumilla, K. M., Jenkins, R. B., Aypar, U., Klee, E. W., Kipp, B. R. & Halling, K. C., Oct 20 2016, In : BMC Genomics. 17, 1, 814.

Research output: Contribution to journal › Article

RNA Stability

RNA

Gene Fusion

Poly A

Transcriptome

4 Citations (Scopus)

PPP6R3-USP6 amplification: Novel oncogenic mechanism in malignant nodular fasciitis

Guo, R., Wang, X., Chou, M. M., Asmann, Y., Wenger, D. E., Al-Ibraheemi, A., Molavi, D. W., Aboulafia, A., Jin, L., Fritchie, K., Oliveira, J., Jenkins, R. B., Westendorf, J. J., Dong, J. & Oliveira, A. M., Aug 1 2016, In : Genes Chromosomes and Cancer. 55, 8, p. 640-649 10 p.

Research output: Contribution to journal › Article

Fasciitis

Gene Fusion

Peptide Hydrolases

Up-Regulation

Recurrence

21 Citations (Scopus)

PTEN loss and chromosome 8 alterations in Gleason grade 3 prostate cancer cores predicts the presence of un-sampled grade 4 tumor: implications for active surveillance

Trock, B. J., Fedor, H., Gurel, B., Jenkins, R. B., Knudsen, B. S., Fine, S. W., Said, J. W., Carter, H. B., Lotan, T. L. & de Marzo, A. M., Apr 15 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 8

Prostatic Neoplasms

Neoplasms

PTEN Phosphohydrolase

Neoplasm Grading

7 Citations (Scopus)

Statistical considerations on prognostic models for glioma

Molinaro, A. M., Wrensch, M. R., Jenkins, R. B. & Eckel-Passow, J. E., May 1 2016, In : Neuro-Oncology. 18, 5, p. 609-623 15 p.

Research output: Contribution to journal › Article

Glioma

Decision Making

Therapeutics

Population

Datasets

25 Citations (Scopus)

The Glioma International Case-Control Study: A Report from the Genetic Epidemiology of Glioma International Consortium

Amirian, E. S., Armstrong, G. N., Zhou, R., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Il'Yasova, D., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Johansen, C., Houlston, R. S., Jenkins, R. B., Lachance, D. H., Olson, S. H., Bernstein, J. L., Merrell, R. T., Wrensch, M. R., Davis, F. G., Lai, R. & 13 others, Shete, S., Amos, C. I., Scheurer, M. E., Aldape, K., Alafuzoff, I., Brännström, T., Broholm, H., Collins, P., Giannini, C., Rosenblum, M., Tihan, T., Melin, B. S. & Bondy, M. L., Jan 15 2016, In : American Journal of Epidemiology. 183, 2, p. 85-91 7 p.

Research output: Contribution to journal › Article

Molecular Epidemiology

Glioma

Case-Control Studies

Gene-Environment Interaction

Brain Neoplasms

2015

22 Citations (Scopus)

A heritable missense polymorphism in CDKN2A confers strong risk of childhood acute lymphoblastic leukemia and is preferentially selected during clonal evolution

Walsh, K. M., De Smith, A. J., Hansen, H. M., Smirnov, I. V., Gonseth, S., Endicott, A. A., Xiao, J., Rice, T., Fu, C. H., McCoy, L. S., Lachance, D. H., Eckel-Passow, J. E., Wiencke, J. K., Jenkins, R. B., Wrensch, M. R., Ma, X., Metayer, C. & Wiemels, J. L., Nov 15 2015, In : Cancer Research. 75, 22, p. 4884-4894 11 p.

Research output: Contribution to journal › Article

Clonal Evolution

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Single Nucleotide Polymorphism

Genome-Wide Association Study

Alleles

1 Citation (Scopus)

A Rare Pediatric Example of Subcutaneous Extraskeletal Osteosarcoma: A Case Report and Review of the Morphologic Differential Diagnosis

Zreik, R. T., Meyer, R. G., Jenkins, R. B., Norambuena, G. A. & Fritchie, K. J., Oct 12 2015, (Accepted/In press) In : American Journal of Dermatopathology.

Research output: Contribution to journal › Article

Osteosarcoma

Differential Diagnosis

Pediatrics

Bone and Bones

Thigh

71 Citations (Scopus)

Characterization of 1577 primary prostate cancers reveals novel biological and clinicopathologic insights into molecular subtypes

Tomlins, S. A., Alshalalfa, M., Davicioni, E., Erho, N., Yousefi, K., Zhao, S., Haddad, Z., Den, R. B., Dicker, A. P., Trock, B. J., Demarzo, A. M., Ross, A. E., Schaeffer, E. M., Klein, E. A., Magi-Galluzzi, C., Karnes, R. J., Jenkins, R. B. & Feng, F. Y., Oct 1 2015, In : European Urology. 68, 4, p. 555-567 13 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Neoplasm Grading

Neoplasms

Seminal Vesicles

Gene Rearrangement

10 Citations (Scopus)

Clinical and genomic analysis of metastatic prostate cancer progression with a background of postoperative biochemical recurrence

Alshalalfa, M., Crisan, A., Vergara, I. A., Ghadessi, M., Buerki, C., Erho, N., Yousefi, K., Sierocinski, T., Haddad, Z., Black, P. C., Karnes, R. J., Jenkins, R. B. & Davicioni, E., Oct 1 2015, In : BJU International. 116, 4, p. 556-567 12 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Neoplasm Metastasis

Recurrence

Prostate-Specific Antigen

Prostatectomy

102 Citations (Scopus)

Combined value of validated clinical and genomic risk stratification tools for predicting prostate cancer mortality in a high-risk prostatectomy cohort

Cooperberg, M. R., Davicioni, E., Crisan, A., Jenkins, R. B., Ghadessi, M. & Karnes, R. J., Feb 1 2015, In : European Urology. 67, 2, p. 326-333 8 p.

Research output: Contribution to journal › Article

Prostatectomy

Prostatic Neoplasms

Mortality

Neoplasms

Decision Support Techniques

8 Citations (Scopus)

Cost-effectiveness of the Decipher Genomic Classifier to Guide Individualized Decisions for Early Radiation Therapy After Prostatectomy for Prostate Cancer

Lobo, J. M., Trifiletti, D., Sturz, V. N., Dicker, A. P., Buerki, C., Davicioni, E., Cooperberg, M. R., Karnes, R. J., Jenkins, R. B., Den, R. B. & Showalter, T. N., Sep 30 2015, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journal › Article

Prostatectomy

Secondary Prevention

Cost-Benefit Analysis

Quality-Adjusted Life Years

Prostatic Neoplasms

9 Citations (Scopus)

Evaluating the clinical impact of a genomic classifier in prostate cancer using individualized decision analysis

Lobo, J. M., Dicker, A. P., Buerki, C., Daviconi, E., Karnes, R. J., Jenkins, R. B., Patel, N., Den, R. B. & Showalter, T. N., Apr 2 2015, In : PLoS One. 10, 4, e0116866.

Research output: Contribution to journal › Article

Decision Support Techniques

Decision theory

prostatic neoplasms

Prostatic Neoplasms

Classifiers

117 Citations (Scopus)

Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group N9831 adjuvant trastuzumab trial

Perez, E. A., Thompson, E. A., Ballman, K. V., Anderson, S. K., Asmann, Y., Kalari, K. R., Eckel-Passow, J. E., Dueck, A., Tenner, K. S., Jen, J., Fan, J. B., Geiger, X. J., McCullough, A. E., Chen, B., Jenkins, R. B., Sledge, G. W., Winer, E. P., Gralow, J. R. & Reinholz, M. M., Mar 1 2015, In : Journal of Clinical Oncology. 33, 7, p. 701-708 8 p.

Research output: Contribution to journal › Article

Genes

Neoplasms

Recurrence

Survival

Politics

87 Citations (Scopus)

Germline mutations in shelterin complex genes are associated with familial glioma

Bainbridge, M. N., Armstrong, G. N., Gramatges, M. M., Bertuch, A. A., Jhangiani, S. N., Doddapaneni, H., Lewis, L., Tombrello, J., Tsavachidis, S., Liu, Y., Jalali, A., Plon, S. E., Lau, C. C., Parsons, D. W., Claus, E. B., Barnholtz-Sloan, J., Il'yasova, D., Schildkraut, J., Ali-Osman, F., Sadetzki, S. & 19 others, Johansen, C., Houlston, R. S., Jenkins, R. B., Lachance, D. H., Olson, S. H., Bernstein, J. L., Merrell, R. T., Wrensch, M. R., Walsh, K. M., Davis, F. G., Lai, R., Shete, S., Aldape, K., Amos, C. I., Thompson, P. A., Muzny, D. M., Gibbs, R. A., Melin, B. S. & Bondy, M. L., Jan 1 2015, In : Journal of the National Cancer Institute. 107, 1, dju384.

Research output: Contribution to journal › Article

Germ-Line Mutation

Glioma

Genes

Mutation

Exome

642 Citations (Scopus)

Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors

Eckel-Passow, J. E., Lachance, D. H., Molinaro, A. M., Walsh, K. M., Decker, P. A., Sicotte, H., Pekmezci, M., Rice, T., Kosel, M. L., Smirnov, I. V., Sarkar, G., Caron, A. A., Kollmeyer, T. M., Praska, C. E., Chada, A. R., Halder, C., Hansen, H. M., McCoy, L. S., Bracci, P. M., Marshall, R. & 16 others, Zheng, S., Reis, G. F., Pico, A. R., O'Neill, B. P., Buckner, J. C., Giannini, C., Huse, J. T., Perry, A., Tihan, T., Berger, M. S., Chang, S. M., Prados, M. D., Wiemels, J., Wiencke, J. K., Wrensch, M. R. & Jenkins, R. B., Jun 25 2015, In : New England Journal of Medicine. 372, 26, p. 2499-2508 10 p.

Research output: Contribution to journal › Article

Glioma

Mutation

Neoplasms

Survival

National Institutes of Health (U.S.)

3 Citations (Scopus)

High-throughput transcriptomic analysis nominates proteasomal genes as age-specific biomarkers and therapeutic targets in prostate cancer

Zhao, S. G., Jackson, W. C., Kothari, V., Schipper, M. J., Erho, N., Evans, J. R., Speers, C., Hamstra, D. A., Niknafs, Y. S., Nguyen, P. L., Schaeffer, E. M., Ross, A. E., Den, R. B., Klein, E. A., Jenkins, R. B., Davicioni, E. & Feng, F. Y., Sep 14 2015, In : Prostate Cancer and Prostatic Diseases. 18, 3, p. 229-236 8 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Biomarkers

Prostatectomy

Genes

Gene Expression

49 Citations (Scopus)

IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas

Leeper, H. E., Caron, A. A., Decker, P. A., Jenkins, R. B., Lachance, D. H. & Giannini, C., 2015, In : Oncotarget. 6, 30, p. 30295-30305 11 p.

Research output: Contribution to journal › Article

Glioma

Mutation

Survival

Biopsy

Oligodendroglioma

35 Citations (Scopus)

Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk

ENGAGE Consortium Telomere Group, 2015, In : Oncotarget. 6, 40, p. 42468-42477 10 p.

Research output: Contribution to journal › Article

Telomere

Glioma

Leukocytes

Single Nucleotide Polymorphism

Gene Components

41 Citations (Scopus)

Multi-parametric MRI and texture analysis to visualize spatial histologic heterogeneity and tumor extent in glioblastoma

Hu, L. S., Ning, S., Eschbacher, J. M., Gaw, N., Dueck, A., Smith, K. A., Nakaji, P., Plasencia, J., Ranjbar, S., Price, S. J., Tran, N., Loftus, J. C., Jenkins, R. B., O'Neill, B. P., Elmquist, W., Baxter, L. C., Gao, F., Frakes, D., Karis, J. P., Zwart, C. & 5 others, Swanson, K., Sarkaria, J. N., Wu, T., Mitchell, J. R. & Li, J., Nov 1 2015, In : PLoS One. 10, 11, e0141506.

Research output: Contribution to journal › Article

Glioblastoma

Magnetic resonance imaging

Tumors

Textures

texture

6 Citations (Scopus)

Neuro-oncology practice: Understanding inherited genetic risk of adult glioma - A review

Rice, T., Lachance, D. H., Molinaro, A. M., Eckel-Passow, J. E., Walsh, K. M., Barnholtz-Sloan, J., Ostrom, Q. T., Francis, S. S., Wiemels, J., Jenkins, R. B., Wiencke, J. K. & Wrensch, M. R., Mar 20 2015, In : Neuro-Oncology Practice. 3, 1, p. 1-16 16 p., npv026.

Research output: Contribution to journal › Article

Glioma

Chromosomes, Human, Pair 8

Neoplasms

Astrocytoma

Histology

7 Citations (Scopus)

Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131

Vogelbaum, M. A., Hu, C., Peereboom, D. M., Macdonald, D. R., Giannini, C., Suh, J. H., Jenkins, R. B., Laack, N. N., Brachman, D. G., Shrieve, D. C., Souhami, L. & Mehta, M. P., Jun 19 2015, In : Journal of Neuro-Oncology. 124, 3, p. 413-420 8 p.

Research output: Contribution to journal › Article

temozolomide

Oligodendroglioma

Astrocytoma

Radiotherapy

Disease-Free Survival

16 Citations (Scopus)

Reply to E.A. Rakha et al

Wolff, A. C., Elizabeth, M., Hammond, H., Hicks, D. G., Allison, K. H., Bartlett, J. M. S., Bilous, M., Fitzgibbons, P., Hanna, W., Jenkins, R. B., Mangu, P. B., Paik, S., Perez, E. A., Press, M. F., Spears, P. A., Vance, G. H., Viale, G., Dowsett, M., McShane, L. M. & Hayes, D. F., Mar 20 2015, In : Journal of Clinical Oncology. 33, 11, p. 1302-1303 2 p.

Research output: Contribution to journal › Article

79 Citations (Scopus)

Survival and low-grade glioma: The emergence of genetic information

Claus, E. B., Walsh, K. M., Wiencke, J. K., Molinaro, A. M., Wiemels, J. L., Schildkraut, J. M., Bondy, M. L., Berger, M., Jenkins, R. B. & Wrensch, M., 2015, In : Neurosurgical Focus. 38, 1, E6.

Research output: Contribution to journal › Article

Glioma

Survival

Neoplasms

SEER Program

National Cancer Institute (U.S.)

14 Citations (Scopus)

Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium

Jalali, A., Amirian, E. S., Bainbridge, M. N., Armstrong, G. N., Liu, Y., Tsavachidis, S., Jhangiani, S. N., Plon, S. E., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Il'yasova, D., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Johansen, C., Houlston, R. S., Jenkins, R. B., Lachance, D. H., Olson, S. H. & 12 others, Bernstein, J. L., Merrell, R. T., Wrensch, M. R., Davis, F. G., Lai, R., Shete, S., Aldape, K., Amos, C. I., Muzny, D. M., Gibbs, R. A., Melin, B. S. & Bondy, M. L., Feb 5 2015, In : Scientific Reports. 5, 8278.

Research output: Contribution to journal › Article

Glioma

Chromosomes

Brain Neoplasms

Genes

Neoplasms

36 Citations (Scopus)

Telomere maintenance and the etiology of adult glioma

Walsh, K. M., Wiencke, J. K., Lachance, D. H., Wiemels, J. L., Molinaro, A. M., Eckel-Passow, J. E., Jenkins, R. B. & Wrensch, M. R., Nov 1 2015, In : Neuro-Oncology. 17, 11, p. 1445-1452 8 p.

Research output: Contribution to journal › Article

Telomere

Glioma

Maintenance

Mutation

Telomere Homeostasis

2014

79 Citations (Scopus)

A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy

Ross, A. E., Feng, F. Y., Ghadessi, M., Erho, N., Crisan, A., Buerki, C., Sundi, D., Mitra, A. P., Vergara, I. A., Thompson, D. J. S., Triche, T. J., Davicioni, E., Bergstralh, E. J., Jenkins, R. B., Karnes, R. J. & Schaeffer, E. M., Mar 2014, In : Prostate Cancer and Prostatic Diseases. 17, 1, p. 64-69 6 p.

Research output: Contribution to journal › Article

Prostatectomy

Disease Progression

Recurrence

Neoplasm Metastasis

Neoplasm Grading

20 Citations (Scopus)

A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma

Catteau, A., Girardi, H., Monville, F., Poggionovo, C., Carpentier, S., Frayssinet, V., Voss, J., Jenkins, R. B., Boisselier, B., Mokhtari, K., Sanson, M., Peyro-Saint-Paul, H. & Giannini, C., 2014, In : Acta neuropathologica communications. 2, p. 58 1 p.

Research output: Contribution to journal › Article

Glioma

Polymerase Chain Reaction

Mutation

Immunohistochemistry

Paraffin

219 Citations (Scopus)

Benefit from procarbazine, lomustine and vincristine in oligodendroglial tumors is associated with mutation of IDH

Cairncross, J. G., Wang, M., Jenkins, R. B., Shaw, E. G., Giannini, C., Brachman, D. G., Buckner, J. C., Fink, K. L., Souhami, L., Laperriere, N. J., Huse, J. T., Mehta, M. P. & Curran, W. J., Mar 10 2014, In : Journal of Clinical Oncology. 32, 8, p. 783-790 8 p.

Research output: Contribution to journal › Article

Lomustine

Procarbazine

Vincristine

Chemoradiotherapy

Mutation

46 Citations (Scopus)

Central pathology laboratory review of HER2 and ER in early breast cancer: An ALTTO trial [BIG 2-06/NCCTG N063D (Alliance)] ring study

McCullough, A. E., Dell'Orto, P., Reinholz, M. M., Gelber, R. D., Dueck, A., Russo, L., Jenkins, R. B., Andrighetto, S., Chen, B., Jackisch, C., Untch, M., Perez, E. A., Piccart-Gebhart, M. J. & Viale, G., Feb 2014, In : Breast Cancer Research and Treatment. 143, 3, p. 485-492 8 p.

Research output: Contribution to journal › Article

Estrogen Receptors

Pathology

Breast Neoplasms

Antibodies

human ERBB2 protein

Editorial commentary on Analysis of IDH mutation, 1p19q deletion, and PTEN loss delineates prognosis in clinical low-grade gliomas

Jenkins, R. B., 2014, In : Neuro-Oncology. 16, 7, p. 891-892 2 p.

Research output: Contribution to journal › Article

Sequence Deletion

Tumor Biomarkers

Brain Neoplasms

Glioma

35 Citations (Scopus)

Effective intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain

Meng, Y., Sohar, I., Sleat, D. E., Richardson, J. R., Reuhl, K. R., Jenkins, R. B., Sarkar, G. & Lobel, P., 2014, In : Molecular Therapy. 22, 3, p. 547-553 7 p.

Research output: Contribution to journal › Article

Neurodegenerative Diseases

Blood-Brain Barrier

Neuronal Ceroid-Lipofuscinoses

Lysosomal Storage Diseases

Peptides

8 Citations (Scopus)

Germline rearrangements in families with strong family history of glioma and malignant melanoma colon, and breast cancer

Andersson, U., Wibom, C., Cederquist, K., Aradottir, S., Borg, Å., Armstrong, G. N., Shete, S., Lau, C. C., Bainbridge, M. N., Claus, E. B., Barnholtz-Sloan, J., Lai, R., Il'yasova, D., Houlston, R. S., Schildkraut, J., Bernstein, J. L., Olson, S. H., Jenkins, R. B., Lachance, D. H., Wrensch, M. & 6 others, Davis, F. G., Merrell, R., Johansen, C., Sadetzki, S., Bondy, M. L. & Petersen, G. M., 2014, In : Neuro-Oncology. 16, 10, p. 1333-1340 8 p.

Research output: Contribution to journal › Article

Glioma

Colonic Neoplasms

Melanoma

Breast Neoplasms

Neoplasms

19 Citations (Scopus)

HER-2/neu gene amplification in relation to expression of HER2 and HER3 proteins in patients with esophageal adenocarcinoma

Yoon, H. H., Sukov, W. R., Shi, Q. D., Sattler, C. A., Wiktor, A. E., Diasio, R. B., Wu, T. T., Jenkins, R. B. & Sinicrope, F. A., Feb 1 2014, In : Cancer. 120, 3, p. 415-424 10 p.

Research output: Contribution to journal › Article

erbB-2 Genes

Gene Amplification

Epidermal Growth Factor Receptor

Adenocarcinoma

Proteins

65 Citations (Scopus)

Obesity and risk of esophageal adenocarcinoma and barrett's esophagus: A mendelian randomization study

Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry Consortium, Ashman, J. B., Bouras, E. P., Cassivi, S. D., Crowell, M. D., De Groen, P., Erlichman, C., Fitch, T. R., Fleischer, D. E., Foxx-Orenstein, A. E., Halling, K. C., Houghton, L. A., Keaveny, A. P., Locke, G. R. & Martenson, J. A., Nov 1 2014, In : Journal of the National Cancer Institute. 106, 11, dju252.

Research output: Contribution to journal › Article

Barrett Esophagus

Random Allocation

Body Mass Index

Obesity

Adenocarcinoma

13 Citations (Scopus)

Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain

Sarkar, G., Curran, G. L., Sarkaria, J. N., Lowe, V. & Jenkins, R. B., May 21 2014, In : PLoS One. 9, 5, e97655.

Research output: Contribution to journal › Article

methotrexate

cisplatin

Methotrexate

Cisplatin

Brain

532 Citations (Scopus)

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American society of clinical oncology/college of American pathologists clinical practice guideline update

Wolff, A. C., Hammond, M. E. H., Hicks, D. G., Dowsett, M., McShane, L. M., Allison, K. H., Allred, D. C., Bartlett, J. M. S., Bilous, M., Fitzgibbons, P., Hanna, W., Jenkins, R. B., Mangu, P. B., Paik, S., Perez, E. A., Press, M. F., Spears, P. A., Vance, G. H., Viale, G. & Hayes, D. F., Feb 2014, In : Archives of Pathology and Laboratory Medicine. 138, 2, p. 241-256 16 p.

Research output: Contribution to journal › Article

Medical Oncology

Practice Guidelines

Breast Neoplasms

In Situ Hybridization

Immunohistochemistry

128 Citations (Scopus)

RNA biomarkers associated with metastatic progression in prostate cancer: A multi-institutional high-throughput analysis of SChLAP1

Prensner, J. R., Zhao, S., Erho, N., Schipper, M., Iyer, M. K., Dhanasekaran, S. M., Magi-Galluzzi, C., Mehra, R., Sahu, A., Siddiqui, J., Davicioni, E., Den, R. B., Dicker, A. P., Karnes, R. J., Wei, J. T., Klein, E. A., Jenkins, R. B., Chinnaiyan, A. M. & Feng, F. Y., 2014, In : The Lancet Oncology. 15, 13, p. 1469-1480 12 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Biomarkers

Long Noncoding RNA

RNA

Neoplasm Grading

21 Citations (Scopus)

The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma

Kizilbash, S., Giannini, C., Voss, J. S., Decker, P. A., Jenkins, R. B., Hardie, J., Laack, N. N., Parney, I. F., Uhm, J. H. & Buckner, J. C., Sep 27 2014, In : Journal of Neuro-Oncology. 120, 1, p. 85-93 9 p.

Research output: Contribution to journal › Article

temozolomide

Isocitrate Dehydrogenase

Astrocytoma

Radiation

Mutation

69 Citations (Scopus)

The IncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer

Prensner, J. R., Sahu, A., Iyer, M. K., Malik, R., Chandler, B., Asangani, I. A., Poliakov, A., Vergara, I. A., Alshalalfa, M., Jenkins, R. B., Davicioni, E., Feng, F. Y. & Chinnaiyan, A. M., 2014, In : Oncotarget. 5, 6, p. 1434-1438 5 p.

Research output: Contribution to journal › Article

Castration

Androgen Receptors

Prostatic Neoplasms

Long Noncoding RNA

RNA Sequence Analysis

286 Citations (Scopus)

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

Chakravarty, D., Sboner, A., Nair, S. S., Giannopoulou, E., Li, R., Hennig, S., Mosquera, J. M., Pauwels, J., Park, K., Kossai, M., Macdonald, T. Y., Fontugne, J., Erho, N., Vergara, I. A., Ghadessi, M., Davicioni, E., Jenkins, R. B., Palanisamy, N., Chen, Z., Nakagawa, S. & 6 others, Hirose, T., Bander, N. H., Beltran, H., Fox, A. H., Elemento, O. & Rubin, M. A., 2014, In : Nature Communications. 5, 5383.

Research output: Contribution to journal › Article

Long Noncoding RNA

estrogens

Estrogen Receptor alpha

Androgen Receptors

Modulators

77 Citations (Scopus)

Tumorgrafts as in vivo surrogates for women with ovarian cancer

Weroha, S. J., Becker, M. A., Enderica-Gonzalez, S., Harrington, S. C., Oberg, A. L., Maurer, M. J., Perkins, S. E., AlHilli, M., Butler, K. A., McKinstry, S., Fink, S., Jenkins, R. B., Hou, X., Kalli, K. R., Goodman, K. M., Sarkaria, J. N., Karlan, B. Y., Kumar, A., Kaufmann, S. H., Hartmann, L. C. & 1 others, Haluska, P., 2014, In : Clinical Cancer Research. 20, 5, p. 1288-1297 10 p.

Research output: Contribution to journal › Article

Ovarian Neoplasms

Neoplasms

SCID Mice

Fallopian Tubes

Platinum

103 Citations (Scopus)

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk

Walsh, K. M., Codd, V., Smirnov, I. V., Rice, T., Decker, P. A., Hansen, H. M., Kollmeyer, T., Kosel, M. L., Molinaro, A. M., McCoy, L. S., Bracci, P. M., Cabriga, B. S., Pekmezci, M., Zheng, S., Wiemels, J. L., Pico, A. R., Tihan, T., Berger, M. S., Chang, S. M., Prados, M. D. & 9 others, Lachance, D. H., O'Neill, B. P., Sicotte, H., Eckel-Passow, J. E., Van Der Harst, P., Wiencke, J. K., Samani, N. J., Jenkins, R. B. & Wrensch, M. R., 2014, In : Nature Genetics. 46, 7, p. 731-735 5 p.

Research output: Contribution to journal › Article

Telomere

Glioma

Leukocytes

Alleles

Genome-Wide Association Study

2013

40 Citations (Scopus)

Analysis of 60 Reported Glioma Risk SNPs Replicates Published GWAS Findings but Fails to Replicate Associations From Published Candidate-Gene Studies

Walsh, K. M., Anderson, E., Hansen, H. M., Decker, P. A., Kosel, M. L., Kollmeyer, T., Rice, T., Zheng, S., Xiao, Y., Chang, J. S., Mccoy, L. S., Bracci, P. M., Wiemels, J. L., Pico, A. R., Smirnov, I., Lachance, D. H., Sicotte, H., Eckel-Passow, J. E., Wiencke, J. K., Jenkins, R. B. & 1 others, Wrensch, M. R., Feb 2013, In : Genetic Epidemiology. 37, 2, p. 222-228 7 p.

Research output: Contribution to journal › Article

Glioma

Single Nucleotide Polymorphism

Genes

Genetic Association Studies

erbB-1 Genes

24 Citations (Scopus)

Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma

Drucker, K. L., Paulsen, A. R., Giannini, C., Decker, P. A., Blaber, S. I., Blaber, M., Uhm, J. H., O'Neill, B. P., Jenkins, R. B. & Scarisbrick, I. A., Mar 2013, In : Neuro-Oncology. 15, 3, p. 305-318 14 p.

Research output: Contribution to journal › Article

Kallikreins

Glioblastoma

Cytotoxins

Survival

temozolomide