Richard M Weinshilboum, MD

  • 28270 Citations
  • 85 Scopus h-Index
1968 …2020

Research output per year

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Research Output

1982

Platelet phenol sulfotransferase activity: Correlation with sulfate conjugation of acetaminophen

Reiter, C. & Weinshilboum, R., Nov 1982, In : Clinical pharmacology and therapeutics. 32, 5, p. 612-621 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Rat phenol sulfotransferase. Assay procedure, developmental changes, and glucocorticoid regulation

Maus, T. P., Pearson, R. K., Anderson, R. J., Woodson, L. C., Reiter, C. & Weinshilboum, R. M., Mar 1 1982, In : Biochemical Pharmacology. 31, 5, p. 849-856 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Thiopurine methyltransferase biochemical genetics: Human lymphocyte activity

Van Loon, J. A. & Weinshilboum, R. M., Aug 1 1982, In : Biochemical Genetics. 20, 7-8, p. 637-658 22 p.

Research output: Contribution to journalArticle

81 Scopus citations
1981

Biochemical genetics of human erythrocyte (RBC) thiopurine methyltransferase (TPMT): Correlation of immunoreactive protein with enzyme activity

Woodson, L. C., Dunnette, J. H. & Weinshilboum, R. M., Jan 1 1981, In : Pharmacologist. 23, 3, p. No. 234

Research output: Contribution to journalArticle

1 Scopus citations

Catechol-O-methyltransferase biochemical genetics: Human lymphocyte enzyme

Sladek-Chelgren, S. & Weinshilboum, R. M., Dec 1 1981, In : Biochemical Genetics. 19, 11-12, p. 1037-1053 17 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genetics of red cell COMT activity: Analysis of thermal stability and family data

Spielman, R. S. & Weinshilboum, R. M., Jan 1 1981, In : American journal of medical genetics. 10, 3, p. 279-290 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

Human plasma dopamine-β-hydroxylase: Oxygen and thermal stability

Dunnette, J. & Weinshilboum, R., Feb 1 1981, In : Experientia. 37, 2, p. 115-117 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Human platelet phenol sulphotransferase: Assay procedure, substrate and tissue correlations

Anderson, R. J., Weinshilboum, R. M., Phillips, S. F. & Broughton, D. D., Mar 5 1981, In : Clinica Chimica Acta. 110, 2-3, p. 157-167 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

Human thiopurine methyltransferase (TPMT) biochemical genetics

Dunnette, J., Chelgren, S. S., Woodson, L. C. & Weinshilboum, R., Jan 1 1981, In : Pharmacologist. 23, 3, p. No. 233

Research output: Contribution to journalArticle

2 Scopus citations

Radioimmunoassay and Immunotitration of Human Serum Dopamine β-Hydroxylase

Dunnette, J. & Weinshilboum, R., Jan 1 1981, In : Methods in enzymology. 74, C, p. 370-380 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Rat thiopurine methyltransferase: Regulation by testosterone

Woodson, L. C., Maus, T. P., Reiter, C. & Weinshilboum, R. M., Jan 1 1981, In : Journal of Pharmacology and Experimental Therapeutics. 218, 3, p. 734-738 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Rat thiopurine methyltransferase assay procedure, developmental changes and strain variation

Walker, R. C., Woodson, L. C. & Weinshilboum, R. M., Jan 15 1981, In : Biochemical Pharmacology. 30, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Testosterone regulation of rat kidney thiopurine methyltransferase (TPMT)

Woodson, L. C., Maus, T. P., Reiter, C. & Weinshilboum, R. M., Jan 1 1981, In : Federation Proceedings. 40, 3 I, p. No. 2496

Research output: Contribution to journalArticle

44 Scopus citations
1980

Antihypertensive drugs that alter adrenergic function

Weinshilboum, R. M., Jan 1 1980, In : Mayo Clinic proceedings. 55, 6, p. 390-402 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Developmental Patterns of Catechol‐O‐Methyltransferase in Genetically Different Rat Strains: Enzymatic and Immunochemical Studies

Goldstein, D. J., Weinshilboum, R. M., Dunnette, J. H. & Creveling, C. R., Jan 1980, In : Journal of neurochemistry. 34, 1, p. 153-162 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Effect of dexamethasone on rat phenolsulphotransferase (PST) activity

Maus, T. P., Anderson, R. J. & Weinshilboum, R. M., Jan 1 1980, In : Pharmacologist. 22, 3, p. No. 773

Research output: Contribution to journalArticle

1 Scopus citations

Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity

Weinshilboum, R. M. & Sladek, S. L., Jan 1 1980, In : American journal of human genetics. 32, 5, p. 651-662 12 p.

Research output: Contribution to journalArticle

1021 Scopus citations

'Methylator status' and assessment of variation in drug metabolism

Weinshilboum, R. M., 1980, In : Trends in Pharmacological Sciences. 1, 2, p. 378-380 3 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Methyl conjugation in uraemia: catechol‐O‐methyltransferase.

Pazmino, PA. & Weinshilboum, RM., Nov 1980, In : British Journal of Clinical Pharmacology. 10, 5, p. 509-518 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phenolsulphotransferase in human tissue: Radiochemical enzymatic assay and biochemical properties

Anderson, R. J. & Weinshilboum, R. M., Apr 11 1980, In : Clinica Chimica Acta. 103, 1, p. 79-90 12 p.

Research output: Contribution to journalArticle

130 Scopus citations

Rat thiopurine methyltransferase (TPMT): Developmental and strain variation

Walker, R., Woodson, L. & Weinshilboum, R., Jan 1 1980, In : Pharmacologist. 22, 3, 1 p.

Research output: Contribution to journalArticle

Thiol S‐methylation in uremia: Erythrocyte enzyme activities and plasma inhibitors

Pazmiño, P. A., Sladek, S. L. & Weinshilboum, R. M., Sep 1980, In : Clinical Pharmacology & Therapeutics. 28, 3, p. 356-367 12 p.

Research output: Contribution to journalArticle

51 Scopus citations
1979

Catechol-O-methyltransferase: Thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity

Scanlon, P. D., Raymond, F. A. & Weinshilboum, R. M., Jan 1 1979, In : Science. 203, 4375, p. 63-65 3 p.

Research output: Contribution to journalArticle

125 Scopus citations

CHARACTERIZATION OF THE BASIS FOR DIFFERENCES IN SERUM DBH ACTIVITY IN IMMATURE AND ADULT RATS BY USE OF HOMOLOGOUS ANTIBODY

Grzanna, R., Nelson, M. F., Weinshilboum, R. M., Dunnette, J. & Coyle, J. T., Oct 1979, In : Journal of neurochemistry. 33, 4, p. 913-921 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human erythrocyte thiol methyltransferase: Radiochemical microassay and biochemical properties

Weinshilboum, R. M., Sladek, S. & Klumpp, S., Sep 15 1979, In : Clinica Chimica Acta. 97, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Human plasma dopamine-beta-hydroxylase: Variation in thermal stability

Dunnette, J. & Weinshilboum, R., Jan 1 1979, In : Molecular pharmacology. 15, 3, p. 649-660 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hypertension, a biomedical genetic approach.

Weinshilboum, R., Dec 1 1979, In : Progress in clinical and biological research. 32, p. 157-181 25 p.

Research output: Contribution to journalReview article

2 Scopus citations

Inhibition of human erythrocyte phenol-O-methyltransferase in uremia

Pazmino, P., Rogoff, F. & Weinshilboum, R., Jan 1 1979, In : Clinical Research. 27, 2, p. 237A

Research output: Contribution to journalArticle

Inhibition of human erythrocyte phenol-O-methyltransferase in uremia

Pazmiño, P., Rogoff, F. & Weinshilbourn, R., Oct 1979, In : Clinical pharmacology and therapeutics. 26, 4, p. 464-472 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mercaptopurine pharmacogenetics: Inherited lack of thiopurine methyltransferase activity

Weinshilboum, R. M. & Sladek, S. L., Jan 1 1979, In : Clinical Research. 27, 4, p. 631A

Research output: Contribution to journalArticle

2 Scopus citations

Monogenic inheritance of catechol-O-methyltransferase activity in the rat-biochemical and genetic studies

Weinshilboum, R. M., Raymond, F. A. & Frohnauer, M., Apr 1 1979, In : Biochemical Pharmacology. 28, 7, p. 1239-1247 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Phenolsulphotransferase: Enzyme activity and endogenous inhibitors in the human erythrocyte

Anderson, R. J. & Weinshilboum, R. M., Dec 1 1979, In : Journal of Laboratory and Clinical Medicine. 94, 1, p. 158-171 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Thiopurine methyltransferase in uremia: Elevated erythrocyte activity and plasma inhibitors

Pazmino, P. A., Sladek, S. L. & Weinshilboum, R. M., Jan 1 1979, In : Clinical Research. 27, 4, p. 668A

Research output: Contribution to journalArticle

1 Scopus citations
1978

Erythrocyte catechol-O-methyltransferase and plasma dopamine-β-hydroxylase in human umbilical cord blood

Weinshilboum, R. M., Dunnette, J., Raymond, F. & Kleinberg, F., Mar 1 1978, In : Experientia. 34, 3, p. 310-311 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Human biochemical genetics of plasma dopamine-β-hydroxylase and erythrocyte catechol-O-methyltransferase

Weinshilboum, Jan 1 1978, In : Human genetics. 45, SUPPL. 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human erythrocyte catechol-o-methyltransferase: Correlation with lung and kidney activity

Weinshilboum, R. M., Feb 1978, In : Life Sciences. 22, 7, p. 625-630 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Human erythrocyte phenol O-methyltransferase: Radiochemical microassay and biochemical properties

Pazmiño, P. A. & Weinshilboum, R. M., Oct 16 1978, In : Clinica Chimica Acta. 89, 2, p. 317-329 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties

Weinshilboum, R. M., Raymond, F. A. & Pazmiño, P. A., May 2 1978, In : Clinica Chimica Acta. 85, 3, p. 323-333 11 p.

Research output: Contribution to journalArticle

263 Scopus citations

Human erythrocyte thiopurine methyltransferase activity

Weinshilboum, R. M., Jan 1 1978, In : Clinical pharmacology and therapeutics. 23, 1, 1 p.

Research output: Contribution to journalArticle

Inheritance of low serum immunoglobulin D

Dunnette, S. L., Gleich, G. J. & Weinshilboum, R. M., 1978, In : Journal of Clinical Investigation. 62, 2, p. 248-255 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Phenolsulphotransferase (PST): Presence of enzyme activity and of endogenous inhibitors in the human erythrocyte (RBC)

Anderson, R. J. & Weinshilboum, R. M., Jan 1 1978, In : Pharmacologist. 20, 3, p. No. 371

Research output: Contribution to journalArticle

1 Scopus citations

Renovascular hypertension. Relationship of surgical curability to renin angiotensin activity

Tucker, R. M., Strong, C. G., Brennan, L. A., Sheps, S. G., Brown, R. D. & Weinshilboum, R. M., Dec 1 1978, In : Mayo Clinic proceedings. 53, 6, p. 373-377 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Serum dopamine β-hydroxylase

Weinshilboum, R. M., Dec 1 1978, In : Pharmacological Reviews. 30, 2, p. 133-166 34 p.

Research output: Contribution to journalReview article

107 Scopus citations
1977
12 Scopus citations
1 Scopus citations

Inheritance of low erythrocyte catechol O methyltransferase activity in man

Weinshilboum, R. M. & Raymond, F. A., Jan 1 1977, In : American journal of human genetics. 29, 2, p. 125-135 11 p.

Research output: Contribution to journalArticle

200 Scopus citations

Inheritance of low immunoreactive human plasma dopamine-β-hydroxylase. Radioimmunoassay studies

Dunnette, J. & Weinshilboum, R., Jan 1 1977, In : Journal of Clinical Investigation. 60, 5, p. 1080-1087 8 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Pathophysiology of Postoperative Ileus

Smith, J., Kelly, K. A. & Weinshilboum, R. M., Feb 1977, In : Archives of Surgery. 112, 2, p. 203-209 7 p.

Research output: Contribution to journalArticle

120 Scopus citations

Serum dopamine β hydroxylase activity and blood pressure

Weinshilboum, R. M., Dec 1 1977, In : Mayo Clinic proceedings. 52, 6, p. 374-378 5 p.

Research output: Contribution to journalArticle

9 Scopus citations