Richard M Weinshilboum, MD

  • 28270 Citations
  • 85 Scopus h-Index
1968 …2020

Research output per year

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Research Output

2015

Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study

Hein, A., Lambrechts, D., Von Minckwitz, G., Häberle, L., Eidtmann, H., Tesch, H., Untch, M., Hilfrich, J., Schem, C., Rezai, M., Gerber, B., Dan Costa, S., Blohmer, J. U., Schwedler, K., Kittel, K., Fehm, T., Kunz, G., Beckmann, M. W., Ekici, A. B., Hanusch, C. & 14 others, Huober, J., Liedtke, C., Mau, C., Moisse, M., Müller, V., Nekljudova, V., Peuteman, G., Rack, B., Rübner, M., Van Brussel, T., Wang, L. M., Weinshilboum, R. M., Loibl, S. & Fasching, P. A., Dec 15 2015, In : International Journal of Cancer. 137, 12, p. 2981-2988 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis

Cummins, N. W., Neuhaus, J., Chu, H., Neaton, J., Wyen, C., Rockstroh, J. K., Skiest, D. J., Boyd, M. A., Khoo, S., Rotger, M., Telenti, A., Weinshilboum, R. M. & Badley, A. D., Jul 1 2015, In : EBioMedicine. 2, 7, p. 706-712 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

KnowEnG: A knowledge engine for genomics

Sinha, S., Song, J., Weinshilboum, R., Jongeneel, V. & Han, J., 2015, In : Journal of the American Medical Informatics Association. 22, 6, p. 1115-1119 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine

Pharmacometabolomics Research Network, Jul 1 2015, In : Clinical Pharmacology and Therapeutics. 98, 1, p. 71-75 5 p.

Research output: Contribution to journalArticle

85 Scopus citations

Mutational landscapes of sequential prostate metastases and matched patient derived xenografts during enzalutamide therapy

Kohli, M., Wang, L., Xie, F., Sicotte, H., Yin, P., Dehm, S. M., Hart, S. N., Vedell, P. T., Barman, P., Qin, R., Mahoney, D. W., Carlson, R. E., Eckel-Passow, J. E., Atwell, T. D., Eiken, P. W., Mcmenomy, B. P., Wieben, E. D., Jha, G., Jimenez, R. E., Weinshilboum, R. & 1 others, Wang, L., Dec 1 2015, In : PloS one. 10, 12, 0145176.

Research output: Contribution to journalArticle

11 Scopus citations

Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity

Levinsen, M., Rosthøj, S., Nygaard, U., Heldrup, J., Harila-Saari, A., Jonsson, O. G., Bechensteen, A. G., Abrahamsson, J., Lausen, B., Frandsen, T. L., Weinshilboum, R. M. & Schmiegelow, K., Jan 1 2015, In : Cancer chemotherapy and pharmacology. 75, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

The International SSRI Pharmacogenomics Consortium (ISPC): A genome-wide association study of antidepressant treatment response

Biernacka, J. M., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T., Leinonen, E., Liou, Y. J., Mushiroda, T. & 12 others, Nonen, S., Skime, M. K., Wang, L., Baune, B. T., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Tsai, S. J., Kubo, M., Klein, T. E. & Weinshilboum, R., May 26 2015, In : Translational psychiatry. 5, 4, A047.

Research output: Contribution to journalArticle

67 Scopus citations

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

KConFab investigators, 2015, In : Oncotarget. 6, 10, p. 7390-7407 18 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Using EHR-Linked Biobank Data to Study Metformin Pharmacogenomics

Breitenstein, M. K., Simon, G., Ryu, E., Armasu, S. M., Weinshilboum, R. M., Wang, L. & Pathak, J., Jan 1 2015, Digital Healthcare Empowering Europeans - Proceedings of MIE 2015. Cornet, R., Stoicu-Tivadar, L., Cornet, R., Parra Calderon, C. L., Andersen, S. K., Horbst, A. & Hercigonja-Szekeres, M. (eds.). IOS Press, p. 914-918 5 p. (Studies in Health Technology and Informatics; vol. 210).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2014

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

Laurie, C. C., Laurie, C. A., Smoley, S. A., Carlson, E. E., Flinn, I., Fridley, B. L., Greisman, H. A., Gribben, J. G., Jelinek, D. F., Nelson, S. C., Paietta, E., Schaid, D., Sun, Z., Tallman, M. S., Weinshilboum, R., Kay, N. E. & Shanafelt, T. D., Jan 2014, In : Cancer Genetics. 207, 1-2, p. 19-30 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Aromatase inhibitor-associated bone fractures: A case-cohort GWAS and functional genomics

Liu, M., Goss, P. E., Ingle, J. N., Kubo, M., Furukawa, Y., Batzler, A., Jenkins, G. D., Carlson, E. E., Nakamura, Y., Schaid, D. J., Chapman, J. A. W., Shepherd, L. E., Ellis, M. J., Khosla, S., Wang, L. & Weinshilboum, R. M., Oct 1 2014, In : Molecular Endocrinology. 28, 10, p. 1740-1751 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations

Ji, Y., Schaid, D. J., Desta, Z., Kubo, M., Batzler, A. J., Snyder, K., Mushiroda, T., Kamatani, N., Ogburn, E., Hall-Flavin, D., Flockhart, D., Nakamura, Y., Mrazek, D. A. & Weinshilboum, R. M., Aug 2014, In : British Journal of Clinical Pharmacology. 78, 2, p. 373-383 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations

Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M. T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J. Y., Dieudonné, A. S., Fasching, P. A., Ferraldeschi, R., Gong, L. & 44 others, Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B. W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J. G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N., Klein, T. E., Boländer, J., Ulmer, H. U., Fischer-Bosch, M., Fritz, P., Simon, W., Bryan, Y., Strick, R., Koelbl, H., Ambrosone, C. A. & H, E. Z., Feb 1 2014, In : Clinical pharmacology and therapeutics. 95, 2, p. 216-227 12 p.

Research output: Contribution to journalArticle

116 Scopus citations

Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

Ingle, J. N., Kalari, K. R., Buzdar, A. U., Robson, M. E., Goetz, M. P., Desta, Z., Barman, P., Dudenkov, T. T., Northfelt, D. W., Perez, E. A., Flockhart, D. A., Williard, C. V., Wang, L. M. & Weinshilboum, R. M., May 1 2014, (Accepted/In press) In : Steroids.

Research output: Contribution to journalArticle

25 Scopus citations

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Karpyak, V. M., Biernacka, J. M., Geske, J. R., Jenkins, G. D., Cunningham, J. M., Rüegg, J., Kononenko, O., Leontovich, A. A., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Skime, M. K., Frank, J., Nöthen, M. M., Rietschel, M., Kiefer, F., Mann, K. F., Weinshilboum, R. M., Frye, M. A. & 1 others, Choi, D. S., 2014, In : Translational psychiatry. 4, p. e462

Research output: Contribution to journalArticle

37 Scopus citations

Genotype-guided dosing of vitamin K antagonists [3]

Pereira, N. L., Rihal, C. S. & Weinshilboum, R. M., Jan 1 2014, In : New England Journal of Medicine. 370, 18, 1 p.

Research output: Contribution to journalLetter

3 Scopus citations

Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer

Pu, X., Wang, L., Chang, J. Y., Hildebrandt, M. A. T., Ye, Y., Lu, C., Skinner, H. D., Niu, N., Jenkins, G. D., Komaki, R., Minna, J. D., Roth, J. A., Weinshilboum, R. M. & Wu, X., Nov 1 2014, In : Clinical pharmacology and therapeutics. 96, 5, p. 609-615 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Metformin pharmacogenomics: Biomarkers to mechanisms

Wang, L. & Weinshilboum, R., Aug 2014, In : Diabetes. 63, 8, p. 2609-2610 2 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

Obesity and risk of esophageal adenocarcinoma and barrett's esophagus: A mendelian randomization study

Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry Consortium, Nov 1 2014, In : Journal of the National Cancer Institute. 106, 11

Research output: Contribution to journalArticle

75 Scopus citations

Pharmacometabolomics: Implications for clinical pharmacology and systems pharmacology

Kaddurah-Daouk, R. & Weinshilboum, R. M., Feb 1 2014, In : Clinical pharmacology and therapeutics. 95, 2, p. 154-167 14 p.

Research output: Contribution to journalArticle

108 Scopus citations

Preemptive genotyping for personalized medicine: Design of the right drug, right dose, right timedusing genomic data to individualize treatment protocol

Bielinski, S. J., Olson, J. E., Pathak, J., Weinshilboum, R. M., Wang, L., Lyke, K. J., Ryu, E., Targonski, P. V., Van Norstrand, M. D., Hathcock, M. A., Takahashi, P. Y., McCormick, J. B., Johnson, K. J., Maschke, K. J., Rohrer Vitek, C. R., Ellingson, M. S., Wieben, E. D., Farrugia, G., Morrisette, J. A., Kruckeberg, K. J. & 15 others, Bruflat, J. K., Peterson, L. M., Blommel, J. H., Skierka, J. M., Ferber, M. J., Black, J. L., Baudhuin, L. M., Klee, E. W., Ross, J. L., Veldhuizen, T. L., Schultz, C. G., Caraballo, P. J., Freimuth, R. R., Chute, C. G. & Kullo, I. J., Jan 2014, In : Mayo Clinic proceedings. 89, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

164 Scopus citations

Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA

Goetz, M. P., Brauch, H., Ratain, M. J., Cox, N. J., Nakamura, Y., Weinshilboum, R. & Ingle, J. N., May 14 2014, In : Journal of the National Cancer Institute. 106, 5, dju063.

Research output: Contribution to journalLetter

3 Scopus citations

The effect of CYP2D6 drug-drug interactions on Hydrocodone effectiveness

Monte, A. A., Heard, K. J., Campbell, J., Hamamura, D., Weinshilboum, R. M. & Vasiliou, V., Aug 2014, In : Academic Emergency Medicine. 21, 8, p. 879-885 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

The eSNV-detect: A computational system to identify expressed single nucleotide variants from transcriptome sequencing data

Tang, X., Baheti, S., Shameer, K., Thompson, K. J., Wills, Q., Niu, N., Holcomb, I. N., Boutet, S. C., Ramakrishnan, R., Kachergus, J. M., Kocher, J. P. A., Weinshilboum, R. M., Wang, L., Thompson, E. A. & Kalari, K. R., Dec 16 2014, In : Nucleic acids research. 42, 22, e172.

Research output: Contribution to journalArticle

22 Scopus citations

Thiopurine pharmacogenomics: Association of SNPs with clinical response and functional validation of candidate genes

Matimba, A., Li, F., Livshits, A., Cartwright, C. S., Scully, S., Fridley, B. L., Jenkins, G., Batzler, A., Wang, L., Weinshilboum, R. & Lennard, L., Mar 2014, In : Pharmacogenomics. 15, 4, p. 433-447 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Treatment outcomes of depression: The pharmacogenomic research network antidepressant medication pharmacogenomic study

Mrazek, D. A., Biernacka, J. M., McAlpine, D. E., Benitez, J., Karpyak, V. M., Williams, M. D., Hall-Flavin, D. K., Netzel, P. J., Passov, V., Rohland, B. M., Shinozaki, G., Hoberg, A. A., Snyder, K. A., Drews, M. S., Skime, M. K., Sagen, J. A., Schaid, D. J., Weinshilboum, R. & Katzelnick, D. J., Jun 2014, In : Journal of Clinical Psychopharmacology. 34, 3, p. 313-317 5 p.

Research output: Contribution to journalArticle

26 Scopus citations
2013
30 Scopus citations

CYP2D6 metabolism and patient outcome in the Austrian breast and colorectal cancer study group trial (ABCSG) 8

Goetz, M. P., Suman, V. J., Hoskin, T. L., Gnant, M., Filipits, M., Safgren, S. L., Kuffel, M., Jakesz, R., Rudas, M., Greil, R., Dietze, O., Lang, A., Offner, F., Reynolds, C. A., Weinshilboum, R. M., Ames, M. M. & Ingle, J. N., Jan 15 2013, In : Clinical Cancer Research. 19, 2, p. 500-507 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

FKBP5 genetic variation: Association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder

Ellsworth, K. A., Moon, I., Eckloff, B. W., Fridley, B. L., Jenkins, G. D., Batzler, A., Biernacka, J. M., Abo, R., Brisbin, A., Ji, Y., Hebbring, S., Wieben, E. D., Mrazek, D. A., Weinshilboum, R. M. & Wang, L., Mar 1 2013, In : Pharmacogenetics and genomics. 23, 3, p. 156-166 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Genome-wide association studies in pharmacogenomics: Successes and lessons

Motsinger-Reif, A. A., Jorgenson, E., Relling, M. V., Kroetz, D. L., Weinshilboum, R., Cox, N. J. & Roden, D. M., Aug 1 2013, In : Pharmacogenetics and genomics. 23, 8, p. 383-394 12 p.

Research output: Contribution to journalReview article

76 Scopus citations

Implementing genomic medicine in the clinic: The future is here

Manolio, T. A., Chisholm, R. L., Ozenberger, B., Roden, D. M., Williams, M. S., Wilson, R., Bick, D., Bottinger, E. P., Brilliant, M. H., Eng, C., Frazer, K. A., Korf, B., Ledbetter, D. H., Lupski, J. R., Marsh, C., Mrazek, D., Murray, M. F., O'Donnell, P. H., Rader, D. J., Relling, M. V. & 5 others, Shuldiner, A. R., Valle, D., Weinshilboum, R., Green, E. D. & Ginsburg, G. S., Sep 1 2013, In : Obstetrical and Gynecological Survey. 68, 9, p. 621-623 3 p.

Research output: Contribution to journalComment/debate

Implementing genomic medicine in the clinic: The future is here

Manolio, T. A., Chisholm, R. L., Ozenberger, B., Roden, D. M., Williams, M. S., Wilson, R., Bick, D., Bottinger, E. P., Brilliant, M. H., Eng, C., Frazer, K. A., Korf, B., Ledbetter, D. H., Lupski, J. R., Marsh, C., Mrazek, D., Murray, M. F., O'Donnell, P. H., Rader, D. J., Relling, M. V. & 5 others, Shuldiner, A. R., Valle, D., Weinshilboum, R., Green, E. D. & Ginsburg, G. S., Apr 1 2013, In : Genetics in Medicine. 15, 4, p. 258-267 10 p.

Research output: Contribution to journalReview article

320 Scopus citations

Incidental genetic findings in randomized clinical trials: Recommendations from the Genomics and Randomized Trials Network (GARNET)

Bookman, E. B., Din-Lovinescu, C., Worrall, B. B., Manolio, T. A., Bennett, S. N., Laurie, C., Mirel, D. B., Doheny, K. F., Anderson, G. L., Wehr, K., Weinshilboum, R. & Chen, D. T., Jan 30 2013, In : Genome medicine. 5, 1, 7.

Research output: Contribution to journalLetter

11 Scopus citations

Interview: Richard M Weinshilboum talks to Hannah Branch, assistant commissioning editor

Weinshilboum, R. M., Feb 1 2013, In : Biomarkers in Medicine. 7, 1, p. 5-10 6 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Mammographic breast density response to aromatase inhibition

Vachon, C. M., Suman, V. J., Brandt, K. R., Kosel, M. L., Buzdar, A. U., Olson, J. E., Wu, F. F., Flickinger, L. M., Ursin, G., Elliott, C. R., Shepherd, L., Weinshilboum, R. M., Goss, P. E. & Ingle, J. N., Apr 15 2013, In : Clinical Cancer Research. 19, 8, p. 2144-2153 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Natriuretic peptide receptor-3 gene (NPR3): Nonsynonymous polymorphism results in significant reduction in protein expression because of accelerated degradation

Pereira, N. L., Lin, D., Pelleymounter, L., Moon, I., Stilling, G., Eckloff, B. W., Wieben, E. D., Redfield, M. M., Burnett, J. C., Yee, V. C. & Weinshilboum, R. M., Apr 1 2013, In : Circulation: Cardiovascular Genetics. 6, 2, p. 201-210 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Nomenclature for alleles of the thiopurine methyltransferase gene

Appell, M. L., Berg, J., Duley, J., Evans, W. E., Kennedy, M. A., Lennard, L., Marinaki, T., McLeod, H. L., Relling, M. V., Schaeffeler, E., Schwab, M., Weinshilboum, R., Yeoh, A. E. J., McDonagh, E. M., Hebert, J. M., Klein, T. E. & Coulthard, S. A., Apr 2013, In : Pharmacogenetics and genomics. 23, 4, p. 242-248 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics

Ji, Y., Biernacka, J. M., Hebbring, S., Chai, Y., Jenkins, G. D., Batzler, A., Snyder, K. A., Drews, M. S., Desta, Z., Flockhart, D., Mushiroda, T., Kubo, M., Nakamura, Y., Kamatani, N., Schaid, D., Weinshilboum, R. M. & Mrazek, D. A., Oct 1 2013, In : Pharmacogenomics Journal. 13, 5, p. 456-463 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: The example of the novel anticancer agent ABT-751

Innocenti, F., Rez, J. R., Obel, J., Xiong, J., Mirkov, S., Chiu, Y. L., Katz, D. A., Carr, R. A., Zhang, W., Das, S., Adjei, A., Moyer, A. M., Chen, P. X., Krivoshik, A., Medina, D., Gordon, G. B., Ratain, M. J., Sahelijo, L., Weinshilboum, R. M., Fleming, G. F. & 1 others, Bhathena, A., Jul 2013, In : Pharmacogenetics and genomics. 23, 7, p. 374-381 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: Individualized breast cancer prevention

Ingle, J. N., Liu, M., Lawrence Wickerham, D., Schaid, D. J., Wang, L., Mushiroda, T., Kubo, M., Costantino, J. P., Vogel, V. G., Paik, S., Goetz, M. P., Ames, M. M., Jenkins, G. D., Batzler, A., Carlson, E. E., Flockhart, D. A., Wolmark, N., Nakamura, Y. & Weinshilboum, R. M., Jul 2013, In : Cancer discovery. 3, 7, p. 812-825 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

TPMT genetic variants are associated with increased rejection with azathioprine use in heart transplantation

Liang, J. J., Geske, J. R., Boilson, B. A., Frantz, R. P., Edwards, B. S., Kushwaha, S. S., Kremers, W. K., Weinshilboum, R. M. & Pereira, N. L., Dec 1 2013, In : Pharmacogenetics and genomics. 23, 12, p. 658-665 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

TSPYl5 SNPs: Association with plasma estradiol concentrations and aromatase expression

Liu, M., Ingle, J. N., Fridley, B. L., Buzdar, A. U., Robson, M. E., Kubo, M., Wang, L., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Perez, E. A., Williard, C. V., Schaid, D. J., Nakamura, Y. & Weinshilboum, R. M., Apr 1 2013, In : Molecular Endocrinology. 27, 4, p. 657-670 14 p.

Research output: Contribution to journalArticle

33 Scopus citations

Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies

Schaid, D. J., Jenkins, G. D., Ingle, J. N. & Weinshilboum, R. M., Apr 1 2013, In : Genetic epidemiology. 37, 3, p. 229-238 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Aromatase inhibitors, estrogens and musculoskeletal pain: Estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression

Liu, M., Wang, L., Bongartz, T., Hawse, J. R., Markovic, S. N., Schaid, D. J., Mushiroda, T., Kubo, M., Nakamura, Y., Kamatani, N., Goss, P. E., Ingle, J. N. & Weinshilboum, R. M., Mar 9 2012, In : Breast Cancer Research. 14, 2, R41.

Research output: Contribution to journalArticle

46 Scopus citations

Automated discovery of drug treatment patterns for endocrine therapy of breast cancer within an electronic medical record

Savova, G. K., Olson, J. E., Murphy, S. P., Cafourek, V. L., Couch, F. J., Goetz, M. P., Ingle, J. N., Suman, V. J., Chute, C. G. & Weinshilboum, R. M., Jun 2012, In : Journal of the American Medical Informatics Association. 19, E1, p. e83-e89

Research output: Contribution to journalArticle

19 Scopus citations

Catechol O-methyltransferase pharmacogenomics and selective serotonin reuptake inhibitor response

Ji, Y., Biernacka, J. M., Snyder, K., Drews, M., Pelleymounter, L. L., Colby, C., Wang, L. M., Mrazek, D. A. & Weinshilboum, R. M., 2012, In : Pharmacogenomics Journal. 12, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation

Ji, Y., Nordgren, K. K. S., Chai, Y., Hebbring, S. J., Jenkins, G. D., Abo, R. P., Peng, Y., Pelleymounter, L. L., Moon, I., Eckloff, B. W., Chai, X., Zhang, J., Fridley, B. L., Yee, V. C., Wieben, E. D. & Weinshilboum, R. M., Oct 2012, In : Drug Metabolism and Disposition. 40, 10, p. 1984-1992 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of a novel percent mammographic density locus at 12q24

Stevens, K. N., Lindstrom, S., Scott, C. G., Thompson, D., Sellers, T. A., Wang, X., Wang, A., Atkinson, E., Rider, D. N., Eckel-passow, J. E., Varghese, J. S., Audley, T., Brown, J., Leyland, J., Luben, R. N., Warren, R. M. L., Loos, R. J. F., Wareham, N. J., Li, J., Hall, P. & 34 others, Liu, J., Eriksson, L., Czene, K., Olson, J. E., Shane pankratz, V., Fredericksen, Z., Diasio, R. B., Lee, A. M., Heit, J. A., Deandrade, M., Goode, E. L., Vierkant, R. A., Cunningham, J. M., Armasu, S. M., Weinshilboum, R., Fridley, B. L., Batzler, A., Ingle, J. N., Boyd, N. F., Paterson, A. D., Rommens, J., Martin, L. J., Hopper, J. L., Southey, M. C., Stone, J., Apicella, C., Kraft, P., Hankinson, S. E., Hazra, A., Hunter, D. J., Easton, D. F., Couch, F. J., Tamimi, R. M. & Vachon, C. M., Jul 2012, In : Human molecular genetics. 21, 14, p. 3299-3305 7 p., dds158.

Research output: Contribution to journalArticle

24 Scopus citations

Interview: An interview with Pharmacogenomics for the breast cancer special focus issue

Weinshilboum, R. M., Apr 1 2012, In : Pharmacogenomics. 13, 6, p. 655-658 4 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics

Abo, R., Hebbring, S., Ji, Y., Zhu, H., Zeng, Z. B., Batzler, A., Jenkins, G. D., Biernacka, J., Snyder, K., Drews, M., Fiehn, O., Fridley, B., Schaid, D., Kamatani, N., Nakamura, Y., Kubo, M., Mushiroda, T., Kaddurah-Daouk, R., Mrazek, D. A. & Weinshilboum, R. M., Apr 1 2012, In : Pharmacogenetics and genomics. 22, 4, p. 247-253 7 p.

Research output: Contribution to journalArticle

45 Scopus citations