Richard M Weinshilboum, MD

  • 28270 Citations
  • 85 Scopus h-Index
1968 …2020

Research output per year

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Research Output

1968

German medical education.

Weinshilboum, R. M., Nov 1 1968, In : The Journal of the Kansas Medical Society. 69, 11, p. 537-542 6 p.

Research output: Contribution to journalArticle

1970

Dopamine-β-hydroxylase activity in the rat after hypophysectomy

Weinshilboum, R. & Axelrod, J., Nov 1970, In : Endocrinology. 87, 5, p. 894-899 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Neurally mediated increase in dopamine-beta-hydroxylase activity.

Molinoff, P. B., Brimijoin, S., Weinshilboum, R. & Axelrod, J., Jun 1970, In : Proceedings of the National Academy of Sciences of the United States of America. 66, 2, p. 453-458 6 p.

Research output: Contribution to journalArticle

Open Access
121 Scopus citations
1971

A sensitive enzymatic assay for dopamine- -hydroxylase.

Molinoff, P. B., Weinshilboum, R. & Axelrod, J., Sep 1 1971, In : Journal of Pharmacology and Experimental Therapeutics. 178, 3, p. 425-431 7 p.

Research output: Contribution to journalArticle

388 Scopus citations

Elevation of serum dopamine-β-hydroxylase activity with forced immobilization

Weinshilboum, R. M., Kvetnansky, R., Axelrod, J. & Kopin, I. J., Apr 28 1971, In : Nature New Biology. 230, 17, p. 287-288 2 p.

Research output: Contribution to journalArticle

85 Scopus citations
Open Access
48 Scopus citations

Proportional release of norepinephrine and dopamine-β-hydroxylase from sympathetic nerves

Weinshilboum, R. M., Thoa, N. B., Johnson, D. G., Kopin, I. J. & Axelrod, J., Jan 1 1971, In : Science. 174, 4016, p. 1349-1351 3 p.

Research output: Contribution to journalArticle

212 Scopus citations

Reduced Plasma Dopamine-β-Hydroxylase Activity in Familial Dysautonomia

Weinshilboum, R. M. & Axelrod, J., Oct 21 1971, In : New England Journal of Medicine. 285, 17, p. 938-942 5 p.

Research output: Contribution to journalArticle

106 Scopus citations

Serum dopamine-beta-hydroxylase activity.

Weinshilboum, R. & Axelrod, J., Mar 1971, In : Circulation research. 28, 3, p. 307-315 9 p.

Research output: Contribution to journalArticle

Open Access
250 Scopus citations

Serum dopamine-β-hydroxylase: Decrease after chemical sympathectomy

Weinshilboum, R. & Axelrod, J., Jan 1 1971, In : Science. 173, 4000, p. 931-934 4 p.

Research output: Contribution to journalArticle

87 Scopus citations
1972

Catecholamines

Axelrod, J. & Weinshilboum, R., Aug 3 1972, In : New England Journal of Medicine. 287, 5, p. 237-242 6 p.

Research output: Contribution to journalReview article

119 Scopus citations

Electrophoretic properties of dopamine -hydroxylase in several tissues from three species.

Ross, S. B., Weinshilboum, R., Molinoff, P. B., Vesell, E. S. & Axelrod, J., Jan 1 1972, In : Molecular pharmacology. 8, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
1973

Serum dopamine-β-hydroxylase activity: Sibling-sibling correlation

Weinshilboum, R. M., Raymond, F. A., Elveback, L. R. & Weidman, W. H., Jan 1 1973, In : Science. 181, 4103, p. 943-945 3 p.

Research output: Contribution to journalArticle

126 Scopus citations

The activity of dopamine beta hydroxylase and methionine activating enzyme in blood of schizophrenic patients

Dunner, D. L., Cohn, C. K., Weinshilboum, R. M. & Wyatt, R. J., Dec 1 1973, In : Biological psychiatry. 6, 3, p. 215-220 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
1974

Correlation of erythrocyte catechol-O-methyltransferase activity between siblings

Weinshilboum, R. M., Raymond, F. A., Elveback, L. R. & Weidman, W. H., Dec 1 1974, In : Nature. 252, 5483, p. 490-491 2 p.

Research output: Contribution to journalArticle

38 Scopus citations

Dopamine-β-hydroxylase activity in serum

Weinshilboum, R. M., Raymond, F. A., Elveback, L. R. & Weidman, W. H., Apr 1974, In : Biochemical Pharmacology. 23, SUPPL. 1, p. 930-936 7 p.

Research output: Contribution to journalArticle

Red blood cell (RBC) catechol O methyltransferase (COMT) activity: sibling-sibling correlation

Weinshilboum, R. M., Raymond, F. A., Elveback, L. R. & Weidman, W. H., Jan 1 1974, In : Pharmacologist. 16, 2, p. no.256

Research output: Contribution to journalArticle

5 Scopus citations
1975

Inheritance of very low serum dopamine β hydroxylase activity

Weinshilboum, R. M., Schorott, H. G., Raymond, F. A., Weidman, W. H. & Elveback, L. R., Dec 1 1975, In : American journal of human genetics. 27, 5, p. 573-585 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Microassay of human erythrocyte catechol-O-methyltransferase: Removal of inhibitory calcium ion with chelating resin

Raymond, F. A. & Weinshilboum, R. M., 1975, In : Clinica Chimica Acta. 58, 2, p. 185-194 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Plasma dopamine beta hydroxylase activity and catecholamine levels in anesthetized dogs following acute hemorrhage

Perry, L. B., Weinshilboum, R. M. & Theye, R. A., Dec 1 1975, In : Anesthesiology. 43, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prolonged hypouricemia associated with acute chlorprothixene ingestion

Weinshilboum, R. M., Goldstein, J. L. & Kelley, W. N., Jan 1 1975, In : Arthritis & Rheumatism. 18, 1 S, p. 739-742 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
1976

A phase I study of cytembena

Frytak, S., Moertel, C. G., Schutt, A. J., Ahmann, D. L., Donadio, J. V. & Weinshilboum, R. M., Mar 1976, In : Cancer. 37, 3, p. 1248-1255 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Calcium inhibition of rat liver catechol-O-methyltransferase

Weinshilboum, R. M. & Raymond, F. A., Mar 1 1976, In : Biochemical Pharmacology. 25, 5, p. 573-579 7 p.

Research output: Contribution to journalArticle

48 Scopus citations
41 Scopus citations

Human inheritance of erythrocyte catechol O methyltransferase (COMT) activity

Weinshilboum, R. M. & Raymond, F. A., Jan 1 1976, In : Pharmacologist. 18, 2, p. No.107

Research output: Contribution to journalArticle

28 Scopus citations

Inhibition of rat liver catechol-O-methyltranferase by lanthanum, neodymium and europium

Quiram, D. R. & Weinshilboum, R. M., Aug 1 1976, In : Biochemical Pharmacology. 25, 15, p. 1727-1732 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Study of Meditation and Blood Pressure

Herxheimer, A., Frankel, B. L., Weinshilboum, R., Stone, R. A. & de Leo, J., Apr 1 1976, In : New England Journal of Medicine. 294, 14, p. 786-787 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
1977
12 Scopus citations
1 Scopus citations

Inheritance of low erythrocyte catechol O methyltransferase activity in man

Weinshilboum, R. M. & Raymond, F. A., Jan 1 1977, In : American journal of human genetics. 29, 2, p. 125-135 11 p.

Research output: Contribution to journalArticle

200 Scopus citations

Inheritance of low immunoreactive human plasma dopamine-β-hydroxylase. Radioimmunoassay studies

Dunnette, J. & Weinshilboum, R., Jan 1 1977, In : Journal of Clinical Investigation. 60, 5, p. 1080-1087 8 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Pathophysiology of Postoperative Ileus

Smith, J., Kelly, K. A. & Weinshilboum, R. M., Feb 1977, In : Archives of Surgery. 112, 2, p. 203-209 7 p.

Research output: Contribution to journalArticle

120 Scopus citations

Serum dopamine β hydroxylase activity and blood pressure

Weinshilboum, R. M., Dec 1 1977, In : Mayo Clinic proceedings. 52, 6, p. 374-378 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

The effect of lesions in the locus coeruleus on the physiological responses of the cerebral blood vessels in cats

Bates, D., Weinshilboum, R. M., Jean Campbell, R. & Sundt, T. M., Nov 18 1977, In : Brain Research. 136, 3, p. 431-443 13 p.

Research output: Contribution to journalArticle

71 Scopus citations

Variations in catechol-O-methyltransferase activity in inbred strains of rats

Weinshilboum, R. & Raymond, F., Oct 1977, In : Neuropharmacology. 16, 10, p. 703-706 4 p.

Research output: Contribution to journalArticle

24 Scopus citations
1978

Erythrocyte catechol-O-methyltransferase and plasma dopamine-β-hydroxylase in human umbilical cord blood

Weinshilboum, R. M., Dunnette, J., Raymond, F. & Kleinberg, F., Mar 1 1978, In : Experientia. 34, 3, p. 310-311 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Human biochemical genetics of plasma dopamine-β-hydroxylase and erythrocyte catechol-O-methyltransferase

Weinshilboum, Jan 1 1978, In : Human genetics. 45, SUPPL. 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human erythrocyte catechol-o-methyltransferase: Correlation with lung and kidney activity

Weinshilboum, R. M., Feb 1978, In : Life Sciences. 22, 7, p. 625-630 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Human erythrocyte phenol O-methyltransferase: Radiochemical microassay and biochemical properties

Pazmiño, P. A. & Weinshilboum, R. M., Oct 16 1978, In : Clinica Chimica Acta. 89, 2, p. 317-329 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties

Weinshilboum, R. M., Raymond, F. A. & Pazmiño, P. A., May 2 1978, In : Clinica Chimica Acta. 85, 3, p. 323-333 11 p.

Research output: Contribution to journalArticle

263 Scopus citations

Human erythrocyte thiopurine methyltransferase activity

Weinshilboum, R. M., Jan 1 1978, In : Clinical pharmacology and therapeutics. 23, 1, 1 p.

Research output: Contribution to journalArticle

Inheritance of low serum immunoglobulin D

Dunnette, S. L., Gleich, G. J. & Weinshilboum, R. M., 1978, In : Journal of Clinical Investigation. 62, 2, p. 248-255 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Phenolsulphotransferase (PST): Presence of enzyme activity and of endogenous inhibitors in the human erythrocyte (RBC)

Anderson, R. J. & Weinshilboum, R. M., Jan 1 1978, In : Pharmacologist. 20, 3, p. No. 371

Research output: Contribution to journalArticle

1 Scopus citations

Renovascular hypertension. Relationship of surgical curability to renin angiotensin activity

Tucker, R. M., Strong, C. G., Brennan, L. A., Sheps, S. G., Brown, R. D. & Weinshilboum, R. M., Dec 1 1978, In : Mayo Clinic proceedings. 53, 6, p. 373-377 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Serum dopamine β-hydroxylase

Weinshilboum, R. M., Dec 1 1978, In : Pharmacological Reviews. 30, 2, p. 133-166 34 p.

Research output: Contribution to journalReview article

107 Scopus citations
1979

Catechol-O-methyltransferase: Thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity

Scanlon, P. D., Raymond, F. A. & Weinshilboum, R. M., Jan 1 1979, In : Science. 203, 4375, p. 63-65 3 p.

Research output: Contribution to journalArticle

125 Scopus citations

CHARACTERIZATION OF THE BASIS FOR DIFFERENCES IN SERUM DBH ACTIVITY IN IMMATURE AND ADULT RATS BY USE OF HOMOLOGOUS ANTIBODY

Grzanna, R., Nelson, M. F., Weinshilboum, R. M., Dunnette, J. & Coyle, J. T., Oct 1979, In : Journal of neurochemistry. 33, 4, p. 913-921 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human erythrocyte thiol methyltransferase: Radiochemical microassay and biochemical properties

Weinshilboum, R. M., Sladek, S. & Klumpp, S., Sep 15 1979, In : Clinica Chimica Acta. 97, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Human plasma dopamine-beta-hydroxylase: Variation in thermal stability

Dunnette, J. & Weinshilboum, R., Jan 1 1979, In : Molecular pharmacology. 15, 3, p. 649-660 12 p.

Research output: Contribution to journalArticle

4 Scopus citations