• 13681 Citations
  • 61 Scopus h-Index
1976 …2020

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2020

Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes

Eckhardt, B. A., Rowsey, J. L., Thicke, B. S., Fraser, D. G., O'Grady, K. L., Bondar, O. P., Hines, J. M., Singh, R. J., Thoreson, A. R., Rakshit, K., Lagnado, A. B., Passos, J. F., Vella, A., Matveyenko, A. V., Khosla, S., Monroe, D. G. & Farr, J. N., May 7 2020, In : JCI Insight. 5, 9, e135236.

Research output: Contribution to journalArticle

Open Access

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Open Access

Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial

MAP.3 Investigators, Jun 1 2020, In : Menopause (New York, N.Y.). 27, 6, p. 693-700 8 p.

Research output: Contribution to journalArticle

Cavernous malformation hemorrhagic presentation at diagnosis associated with low 25-hydroxy-vitamin D level

Flemming, K. D., Kumar, S., Brown, R. D., Singh, R. J., Whitehead, K., McCreath, L. & Lanzino, G., May 1 2020, In : Cerebrovascular Diseases. 49, 2, p. 216-222 7 p.

Research output: Contribution to journalArticle

Center of Mass Calculation in Combination with MS/MS Allows Robust Identification of Single Amino Acid Polymorphisms in Clinical Measurements of Insulin-Like Growth Factor-1

Maus, A., Kemp, J., Milosevic, D., Renuse, S., Pandey, A., Singh, R. J. & Grebe, S. K. G., Jan 3 2020, In : Journal of Proteome Research. 19, 1, p. 186-193 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical and Biochemical Phenotypes in a Family With ENPP1 Mutations

Kotwal, A., Ferrer, A., Kumar, R., Singh, R. J., Murthy, V., Schultz-Rogers, L., Zimmermann, M., Lanpher, B., Zimmerman, K., Stabach, P. R., Klee, E., Braddock, D. T. & Wermers, R. A., Apr 1 2020, In : Journal of Bone and Mineral Research. 35, 4, p. 662-670 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Correlation between size and function of unilateral and bilateral adrenocortical nodules: An observational study

Huayllas, M. K. P., Sirineni, G. K., Smith, L. M., Christopher Gallagher, J., Singh, R. J., Netzel, B. C. & Kater, C. E., 2020, In : American Journal of Roentgenology. 214, 4, p. 800-807 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Determinants and Measurement of Neonatal Vitamin D: Overestimation of 25(OH)D in Cord Blood Using CLIA Assay Technology

Lu, M., Hollis, B. W., Carey, V. J., Laranjo, N., Singh, R. J., Weiss, S. T. & Litonjua, A. A., Apr 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 4

Research output: Contribution to journalArticle

Drug tissue distribution of tudca from a biodegradable suprachoroidal implant versus intravitreal or systemic delivery in the pig model

Olsen, T. W., Dyer, R. B., Mano, F., Boatright, J. H., Chrenek, M. A., Paley, D., Wabner, K., Schmit, J., Chae, J. B., Sellers, J. T., Singh, R. J. & Wiedmann, T. S., May 2020, In : Translational Vision Science and Technology. 9, 6, 11.

Research output: Contribution to journalArticle

Open Access

Risk of iodine deficiency in extremely low gestational age newborns on parenteral nutrition

Kanike, N., Groh-Wargo, S., Thomas, M., Chien, E. K., Mhanna, M., Kumar, D., Worley, S., Singh, R. J. & Shekhawat, P. S., Jun 2020, In : Nutrients. 12, 6, 1636.

Research output: Contribution to journalArticle

Open Access
2019

Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis

Khatua, B., Trivedi, R. N., Noel, P., Patel, K., Singh, R., de Oliveira, C., Trivedi, S., Mishra, V., Lowe, M. & Singh, V. P., Jun 2019, In : American Journal of Pathology. 189, 6, p. 1226-1240 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Catecholamine and Metanephrine Levels in Breast Milk before and after Paraganglioma Resection

Dodd, S. E., Singh, R. J. & Martin, Y. N., May 1 2019, In : Breastfeeding Medicine. 14, 4, p. 276-277 2 p.

Research output: Contribution to journalArticle

Obesity Decreases Hepatic 25-Hydroxylase Activity Causing Low Serum 25-Hydroxyvitamin D

Roizen, J. D., Long, C., Casella, A., O'Lear, L., Caplan, I., Lai, M., Sasson, I., Singh, R., Makowski, A. J., Simmons, R. & Levine, M. A., Jun 2019, In : Journal of Bone and Mineral Research. 34, 6, p. 1068-1073 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

10 years of 25-hydroxyvitamin-D testing by LC-MS/MS-trends in vitamin-D deficiency and sufficiency

Galior, K., Ketha, H., Grebe, S. & Singh, R. J., Jun 1 2018, In : Bone Reports. 8, p. 268-273 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Anogenital distance is determined during early gestation in humans

Jain, V. G., Goyal, V., Chowdhary, V., Swarup, N., Singh, R. J., Singal, A. & Shekhawat, P., 2018, In : Human Reproduction. 33, 9, p. 1619-1627 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Comparison of the effect of daily versus bolus dose maternal vitamin D3 supplementation on the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio

Ketha, H., Thacher, T. D., Oberhelman, S. S., Fischer, P. R., Singh, R. J. & Kumar, R., May 1 2018, In : Bone. 110, p. 321-325 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
1 Scopus citations

Is There a Difference between Ultrasonographic (US) Uterine Changes of Oral Versus Transdermal (TD) 17β Estradiol (17β E2) in Girls with Turner Syndrome (TS)? Own Experience and Literature Review

Kraus, J., Unanue, N., Espinoza, A., Iniguez, G., Torres-Santiago, L., Singh, R. J., Mauras, N. & Mericq, V., Sep 1 2018, In : Pediatric endocrinology reviews : PER. 16, 1, p. 178-185 8 p.

Research output: Contribution to journalArticle

Limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision making

Rahme, M., Al-Shaar, L., Singh, R. J., Baddoura, R., Halaby, G., Arabi, A., Habib, R. H., Daher, R., Bassil, D., El-Ferkh, K., Hoteit, M. & El-Hajj Fuleihan, G., Dec 1 2018, In : Metabolism: Clinical and Experimental. 89, p. 1-7 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Over-the-Counter “Adrenal Support” Supplements Contain Thyroid and Steroid-Based Adrenal Hormones

Akturk, H. K., Chindris, A. M., Hines, J. M., Singh, R. J. & Bernet, V. J., Mar 1 2018, In : Mayo Clinic Proceedings. 93, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Senolytics improve physical function and increase lifespan in old age

Xu, M., Pirtskhalava, T., Farr, J. N., Weigand, B. M., Palmer, A. K., Weivoda, M. M., Inman, C. L., Ogrodnik, M. B., Hachfeld, C. M., Fraser, D. G., Onken, J. L., Johnson, K. O., Verzosa, G. C., Langhi, L. G. P., Weigl, M., Giorgadze, N., LeBrasseur, N. K., Miller, J. D., Jurk, D., Singh, R. J. & 13 others, Allison, D. B., Ejima, K., Hubbard, G. B., Ikeno, Y., Cubro, H., Garovic, V. D., Hou, X., Weroha, S. J., Robbins, P. D., Niedernhofer, L. J., Khosla, S., Tchkonia, T. & Kirkland, J. L., Aug 1 2018, In : Nature Medicine. 24, 8, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

290 Scopus citations

Serum 25-hydroxyvitamin D3 levels and flares of systemic lupus erythematosus: a longitudinal cohort analysis

Mok, C. C., Bro, E. T., Ho, L. Y., Singh, R. J. & Jannetto, P. J., Jul 16 2018, (Accepted/In press) In : Clinical Rheumatology. p. 1-8 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Serum Cortisol Levels via Radioimmunoassay vs Liquid Chromatography Mass Spectrophotometry in Healthy Control Subjects and Patients With Adrenal Incidentalomas

Huayllas, M. K. P., Netzel, B. C., Singh, R. J. & Kater, C. E., Jul 5 2018, In : Laboratory Medicine. 49, 3, p. 259-267 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota

Edogawa, S., Peters, S. A., Jenkins, G. D., Gurunathan, S. V., Sundt, W. J., Johnson, S., Lennon, R. J., Dyer, R. B., Camilleri, M., Kashyap, P. C., Farrugia, G., Chen, J., Singh, R. J. & Grover, M., Dec 1 2018, In : FASEB Journal. 32, 12, p. 6615-6625 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

17α-estradiol alleviates age-related metabolic and inflammatory dysfunction in male mice without inducing feminization

Stout, M. B., Steyn, F. J., Jurczak, M. J., Camporez, J. P. G., Zhu, Y., Hawse, J. R., Jurk, D., Palmer, A. K., Xu, M., Pirtskhalava, T., Evans, G. L., De Souza Santos, R., Frank, A. P., White, T. A., Monroe, D. G., Singh, R. J., Casaclang-Verzosa, G., Miller, J. D., Clegg, D. J., LeBrasseur, N. K. & 4 others, Von Zglinicki, T., Shulman, G. I., Tchkonia, T. & Kirkland, J. L., 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 1, p. 3-15 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results from the MAL-ED Study

Kosek, M. N., Lee, G. O., Guerrant, R. L., Haque, R., Kang, G., Ahmed, T., Bessong, P., Ali, A., Mduma, E., Peñataro Yori, P., Faubion, W. A., Lima, A. A. M., Paredes Olortegui, M., Mason, C., Babji, S., Singh, R., Qureshi, S., Kosek, P. S., Samie, A., Pascal, J. & 7 others, Shrestha, S., McCormick, B. J. J., Seidman, J. C., Lang, D. R., Zaidi, A., Caulfield, L. E. & Gottlieb, M., Jul 1 2017, In : Journal of pediatric gastroenterology and nutrition. 65, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
16 Scopus citations

Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function

Peters, S. A., Edogawa, S., Sundt, W. J., Dyer, R. B., Dalenberg, D. A., Mazzone, A., Singh, R. J., Moses, N., Smyrk, T. C., Weber, C., Linden, D. R., MacNaughton, W. K., Turner, J. R., Camilleri, M., Katzka, D. A., Farrugia, G. & Grover, M., Mar 21 2017, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

13 Scopus citations

Effects of cholecalciferol supplementation on serum and urinary vitamin D metabolites and binding protein in HIV-infected youth

Eckard, A. R., Thierry-Palmer, M., Silvestrov, N., Rosebush, J. C., O'Riordan, M. A., Daniels, J. E., Uribe-Leitz, M., Labbato, D., Ruff, J. H., Singh, R. J., Tangpricha, V. & McComsey, G. A., Apr 1 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 168, p. 38-48 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

High-resolution, accurate-mass (HRAM) mass spectrometry urine steroid profiling in the diagnosis of adrenal disorders

Hines, J. M., Bancos, I., Bancos, C., Singh, R. D., Avula, A. V., Young, W. F., Grebe, S. K. & Singh, R. J., Dec 1 2017, In : Clinical Chemistry. 63, 12, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Hypothalamo-pituitary-adrenal axis after a single epidural triamcinolone injection

Iranmanesh, A., Gullapalli, D., Singh, R. J. & Veldhuis, J. D., Aug 1 2017, In : Endocrine. 57, 2, p. 308-313 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Impact of Calcium and Two Doses of Vitamin D on Bone Metabolism in the Elderly: A Randomized Controlled Trial

Rahme, M., Sharara, S. L., Baddoura, R., Habib, R. H., Halaby, G., Arabi, A., Singh, R. J., Kassem, M., Mahfoud, Z., Hoteit, M., Daher, R. T., Bassil, D., El Ferkh, K. & El-Hajj Fuleihan, G., Jul 1 2017, In : Journal of Bone and Mineral Research. 32, 7, p. 1486-1495 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Measurement of gut permeability using fluorescent tracer agent technology

Dorshow, R. B., Hall-Moore, C., Shaikh, N., Talcott, M. R., Faubion, W. A., Rogers, T. E., Shieh, J. J., Debreczeny, M. P., Johnson, J. R., Dyer, R. B., Singh, R. J. & Tarr, P. I., Dec 1 2017, In : Scientific reports. 7, 1, 10888.

Research output: Contribution to journalArticle

5 Scopus citations

Perspective and priorities for improvement of parathyroid hormone (PTH) measurement – A view from the IFCC Working Group for PTH

IFCC Working Group for PTH, Apr 1 2017, In : Clinica Chimica Acta. 467, p. 42-47 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Role of Mass Spectrometry in Clinical Endocrinology

Ketha, S. S., Singh, R. J. & Ketha, H., 2017, (Accepted/In press) In : Endocrinology and Metabolism Clinics of North America.

Research output: Contribution to journalArticle

10 Scopus citations

Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells

Shenoy, N., Bhagat, T., Nieves, E., Stenson, M., Lawson, J., Choudhary, G. S., Habermann, T. M., Nowakowski, G. S., Singh, R. J., Wu, X., Verma, A. & Witzig, T. E., Jul 21 2017, In : Blood Cancer Journal. 7, 7, p. e587

Research output: Contribution to journalArticle

28 Scopus citations
2016

13C mannitol as a novel biomarker for measurement of intestinal permeability

Grover, M., Camilleri, M., Hines, J., Burton, D., Ryks, M., Wadhwa, A., Sundt, W., Dyer, R. & Singh, R. J., 2016, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

15 Scopus citations

Abnormalities in biomarkers of mineral and bone metabolism in kidney donors

Kasiske, B. L., Kumar, R., Kimmel, P. L., Pesavento, T. E., Kalil, R. S., Kraus, E. S., Rabb, H., Posselt, A. M., Anderson-Haag, T. L., Steffes, M. W., Israni, A. K., Snyder, J. J., Singh, R. J. & Weir, M. R., Mar 9 2016, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical and biochemical phenotypes of adults with monoallelic and biallelic CYP24A1 mutations: evidence of gene dose effect

O’Keeffe, D. T., Tebben, P. J., Kumar, R., Singh, R. J., Wu, Y. & Wermers, R. A., Oct 1 2016, In : Osteoporosis International. 27, 10, p. 3121-3125 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Clinical peptide and protein quantification by mass spectrometry (MS)

Grebe, S. K. G. & Singh, R. J., 2016, (Accepted/In press) In : Trends in Analytical Chemistry.

Research output: Contribution to journalArticle

13 Scopus citations

CYP2R1 polymorphisms are important modulators of circulating 25-hydroxyvitamin D levels in elderly females with vitamin insufficiency, but not of the response to vitamin D supplementation

Arabi, A., Khoueiry-Zgheib, N., Awada, Z., Mahfouz, R., Al-Shaar, L., Hoteit, M., Rahme, M., Baddoura, R., Halabi, G., Singh, R. J. & El Hajj Fuleihan, G., Jul 30 2016, (Accepted/In press) In : Osteoporosis International. p. 1-12 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of Vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: A randomized controlled trial

Fuleihan, G. E. H., Baddoura, R., Habib, R. H., Halaby, G., Arabi, A., Rahme, M., Singh, R. J., Kassem, M., Mahfoud, Z., Hoteit, M., Daher, R. T. & Kassir, M. F., Aug 1 2016, In : American Journal of Clinical Nutrition. 104, 2, p. 315-323 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Dutta, T., Kudva, Y. C., Persson, X. M. T., Schenck, L. A., Charles Ford, G., Singh, R. J., Carter, R. E. & Nair, K. S., Mar 1 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
Open Access
19 Scopus citations

Interleukins 6 and 8 and abdominal fat depots are distinct correlates of lipid moieties in healthy pre- and postmenopausal women

Veldhuis, J. D., Dyer, R. B., Trushin, S. A., Bondar, O. P., Singh, R. J. & Klee, G. G., Jul 22 2016, (Accepted/In press) In : Endocrine. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

LC-MS/MS for identifying patients with CYP24A1 mutations

Ketha, H., Kumar, R. & Singh, R. J., Jan 2016, In : Clinical chemistry. 62, 1, p. 236-242 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis

Gomez-Ospina, N., Potter, C. J., Xiao, R., Manickam, K., Kim, M. S., Kim, K. H., Shneider, B. L., Picarsic, J. L., Jacobson, T. A., Zhang, J., He, W., Liu, P., Knisely, A. S., Finegold, M. J., Muzny, D. M., Boerwinkle, E., Lupski, J. R., Plon, S. E., Gibbs, R. A., Eng, C. M. & 9 others, Yang, Y., Washington, G. C., Porteus, M. H., Berquist, W. E., Kambham, N., Singh, R. J., Xia, F., Enns, G. M. & Moore, D. D., Feb 18 2016, In : Nature Communications. 7, 10713.

Research output: Contribution to journalArticle

91 Scopus citations

Randomized trial of aromatase inhibitors, growth hormone, or combination in pubertal boys with idiopathic, short stature

Mauras, N., Ross, J. L., Gagliardi, P., Yu, Y. M., Hossain, J., Permuy, J., Damaso, L., Merinbaum, D., Singh, R. J., Gaete, X. & Mericq, V., Dec 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 12, p. 4984-4993 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Recommendations for the generation, quantification, storage, and handling of peptides used for mass spectrometry-based assays

Hoofnagle, A. N., Whiteaker, J. R., Carr, S. A., Kuhn, E., Liu, T., Massoni, S. A., Thomas, S. N., Reid Townsend, R., Zimmerman, L. J., Boja, E., Chen, J., Crimmins, D. L., Davies, S. R., Gao, Y., Hiltke, T. R., Ketchum, K. A., Kinsinger, C. R., Mesri, M., Meyer, M. R., Qian, W. J. & 35 others, Schoenherr, R. M., Scott, M. G., Shi, T., Whiteley, G. R., Wrobel, J. A., Wu, C., Ackermann, B. L., Aebersold, R., Barnidge, D. R., Bunk, D. M., Clarke, N., Fishman, J. B., Grant, R. P., Kusebauch, U., Kushnir, M. M., Lowenthal, M. S., Moritz, R. L., Neubert, H., Patterson, S. D., Rockwood, A. L., Rogers, J., Singh, R. J., Van Eyk, J. E., Wong, S. H., Zhang, S., Chan, D. W., Chen, X., Ellis, M. J., Liebler, D. C., Rodland, K. D., Rodriguez, H., Smith, R. D., Zhang, Z., Zhang, H. & Paulovich, A. G., Jan 2016, In : Clinical chemistry. 62, 1, p. 48-69 22 p.

Research output: Contribution to journalArticle

85 Scopus citations

Thyroid hormone testing in the 21st century

Singh, R. J. & Kaur, P., 2016, (Accepted/In press) In : Clinical Biochemistry.

Research output: Contribution to journalArticle

4 Scopus citations