• 31477 Citations
  • 95 Scopus h-Index
19962020

Research output per year

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Research Output

2004

Acquired Fanconi syndrome is an indolent disorder in the absence of overt multiple myeloma

Ma, C. X., Lacy, M., Rompala, J. F., Dispenzieri, A., Rajkumar, S. V., Greipp, P. R., Fonseca, R., Kyle, R. A. & Gertz, M., Jul 1 2004, In : Blood. 104, 1, p. 40-42 3 p.

Research output: Contribution to journalArticle

82 Scopus citations

Analysis of somatic hypermutation and antigenic selection in the clonal B cell in immunoglobulin light chain amyloidosis (AL)

Abraham, R. S., Geyer, S. M., Ramirez-Alvarado, M., Price-Troska, T. L., Gertz, M. & Fonseca, R., Jul 2004, In : Journal of Clinical Immunology. 24, 4, p. 340-353 14 p.

Research output: Contribution to journalArticle

17 Scopus citations

Clinical course of patients with relapsed multiple myeloma

Kumar, S. K., Therneau, T. M., Gertz, M., Lacy, M., Dispenzieri, A., Rajkumar, S. V., Fonseca, R., Witzig, T. E., Lust, J. A., Larson, D. R., Kyle, R. A. & Greipp, P. R., 2004, In : Mayo Clinic Proceedings. 79, 7, p. 867-874 8 p.

Research output: Contribution to journalArticle

209 Scopus citations

Effect of thalidomide therapy on bone marrow angiogenesis in multiple myeloma

Kumar, S. K., Witzig, T. E., Dispenzieri, A., Lacy, M., Wellik, L. E., Fonseca, R., Lust, J. A., Gertz, M., Kyle, R. A., Greipp, P. R. & Rajkumar, S. V., Mar 2004, In : Leukemia. 18, 3, p. 624-627 4 p.

Research output: Contribution to journalArticle

84 Scopus citations

Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma

Alsina, M., Fonseca, R., Wilson, E. F., Belle, A. N., Gerbino, E., Price-Troska, T., Overton, R. M., Ahmann, G., Bruzek, L. M., Adjei, A., Kaufmann, S. H., Wright, J. J., Sullivan, D., Djulbegovic, B., Cantor, A. B., Greipp, P. R., Dalton, W. S. & Sebti, S. M., May 1 2004, In : Blood. 103, 9, p. 3271-3277 7 p.

Research output: Contribution to journalArticle

148 Scopus citations

Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report

Fonseca, R., Barlogie, B., Bataille, R., Bastard, C., Bergsagel, P. L., Chesi, M., Davies, F. E., Drach, J., Greipp, P. R., Kirsch, I. R., Kuehl, W. M., Hernandez, J. M., Minvielle, S., Pilarski, L. M., Shaughnessy, J. D., Stewart, A. K. & Avet-Loiseau, H., Feb 15 2004, In : Cancer Research. 64, 4, p. 1546-1558 13 p.

Research output: Contribution to journalArticle

558 Scopus citations

High-dose therapy and autologous stem cell transplantation for multiple myeloma poorly responsive to initial therapy

Kumar, S. K., Lacy, M., Dispenzieri, A., Rajkumar, S. V., Fonseca, R., Geyer, S., Allmer, S., Witzig, T. E., Lust, J. A., Greipp, P. R., Kyle, R. A., Litzow, M. R. & Gertz, M., Jul 2004, In : Bone Marrow Transplantation. 34, 2, p. 161-167 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Identification of genes modulated in multiple myeloma using genetically identical twin samples

Munshi, N. C., Hideshima, T., Carrasco, D., Shammas, M., Auclair, D., Davies, F., Mitsiades, N., Mitsiades, C., Kim, R. S., Li, C., Rajkumar, S. V., Fonseca, R., Bergsagel, P. L., Chauhan, D. & Anderson, K. C., Mar 1 2004, In : Blood. 103, 5, p. 1799-1806 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

Initial immunoglobulin M 'Flare' after rituximab therapy in patients diagnosed with Waldenstrom macroglobulinemia: An Eastern Cooperative Oncology Group Study

Ghobrial, I. M., Fonseca, R., Greipp, P. R., Blood, E., Rue, M., Vesole, D. H. & Gertz, M., Dec 1 2004, In : Cancer. 101, 11, p. 2593-2598 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Molecular classification of light chain (AL) amyloidosis by gene expression profiling

Abraham, R. S., Manske, M. K., Ballman, K. V., Dispenzieri, A., Price-Troska, T. L., Gertz, M. & Fonseca, R., Jan 1 2004, Amyloid and Amyloidosis. CRC Press, p. 58-60 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Prognostication of survival using cardiac troponins and N-terminal pro-brain natriuretic peptide in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation

Dispenzieri, A., Gertz, M., Kyle, R. A., Lacy, M., Burritt, M. F., Therneau, T. M., McConnell, J. P., Litzow, M. R., Gastineau, D. A., Tefferi, A., Inwards, D. J., Micallef, I., Ansell, S. M., Porrata, L. F., Elliott, M. A., Hogan, W., Rajkumar, S. V., Fonseca, R., Greipp, P. R., Witzig, T. E. & 6 others, Lust, J. A., Zeldenrust, S. R., Snow, D. S., Hayman, S. R., McGregor, C. G. A. & Jaffe, A. S., Sep 15 2004, In : Blood. 104, 6, p. 1881-1887 7 p.

Research output: Contribution to journalArticle

243 Scopus citations

Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy

Kumar, S. K., Gertz, M., Dispenzieri, A., Lacy, M., Wellik, L. A., Fonseca, R., Lust, J. A., Witzig, T. E., Kyle, R. A., Greipp, P. R. & Rajkumar, S. V., Aug 2004, In : Bone Marrow Transplantation. 34, 3, p. 235-239 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Serum cardiac troponins and N-terminal pro-brain natriuretic peptide: A staging system for primary systemic amyloidosis

Dispenzieri, A., Gertz, M., Kyle, R. A., Lacy, M., Burritt, M. F., Therneau, T. M., Greipp, P. R., Witzig, T. E., Lust, J. A., Rajkumar, S. V., Fonseca, R., Zeldenrust, S. R., McGregor, C. G. A. & Jaffe, A. S., 2004, In : Journal of Clinical Oncology. 22, 18, p. 3751-3757 7 p.

Research output: Contribution to journalArticle

508 Scopus citations

Single agent dexamethasone for pre-stem cell transplant induction therapy for multiple myeloma

Kumar, S. K., Lacy, M., Dispenzieri, A., Rajkumar, S. V., Fonseca, R., Geyer, S., Allmer, C., Witzig, T. E., Lust, J. A., Greipp, P. R., Kyle, R. A., Litzow, M. R. & Gertz, M., Sep 2004, In : Bone Marrow Transplantation. 34, 6, p. 485-490 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Superior survival in primary systemic amyloidosis patients undergoing peripheral blood stem cell transplantation: A case-control study

Dispenzieri, A., Kyle, R. A., Lacy, M., Therneau, T. M., Larson, D. R., Plevak, M. F., Rajkumar, S. V., Fonseca, R., Greipp, P. R., Witzig, T. E., Lust, J. A., Zeldenrust, S. R., Snow, D. S., Hayman, S. R., Litzow, M. R., Gastineau, D. A., Tefferi, A., Inwards, D. J., Micallef, I., Ansell, S. M. & 3 others, Porrata, L. F., Elliott, M. A. & Gertz, M., May 15 2004, In : Blood. 103, 10, p. 3960-3963 4 p.

Research output: Contribution to journalArticle

198 Scopus citations

Therapeutic Options in Patients with Lymphoma and Severe Liver Dysfunction

Ghobrial, I. M., Wolf, R. C., Pereira, D. L., Fonseca, R., White, W. L., Colgan, J. P., Habermann, T. M., Inwards, D. J., Markovic, S. N., Ansell, S. M., Micallef, I., Porrata, L. F. & Witzig, T. E., 2004, In : Mayo Clinic Proceedings. 79, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2003

Assays for neoplastic cell enrichment in bone marrow samples.

Fonseca, R. & Ahmann, G. J., 2003, In : Methods in molecular medicine. 85, p. 333-342 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma

Debes-Marun, C. S., Dewald, G. W., Bryant, S., Picken, E., Santana-Dávila, R., González-Paz, N., Winkler, J. M., Kyle, R. A., Gertz, M., Witzig, T. E., Dispenzieri, A., Lacy, M., Rajkumar, S. V., Lust, J. A., Greipp, P. R. & Fonseca, R., Feb 1 2003, In : Leukemia. 17, 2, p. 427-436 10 p.

Research output: Contribution to journalArticle

194 Scopus citations

Circulating peripheral blood plasma cells as a prognostic indicator in patients with primary systemic amyloidosis

Pardanani, A. D., Witzig, T. E., Schroeder, G., McElroy, E. A., Fonseca, R., Dispenzieri, A., Lacy, M., Lust, J. A., Kyle, R. A., Greipp, P. R., Gertz, M. & Rajkumar, S. V., Feb 1 2003, In : Blood. 101, 3, p. 827-830 4 p.

Research output: Contribution to journalArticle

47 Scopus citations

Clinical and biologic implications of recurrent genomic aberrations in myeloma

Fonseca, R., Blood, E., Rue, M., Harrington, D., Oken, M. M., Kyle, R. A., Dewald, G. W., Van Ness, B., Van Wier, S. A., Henderson, K. J., Bailey, R. J. & Greipp, P. R., Jun 1 2003, In : Blood. 101, 11, p. 4569-4575 7 p.

Research output: Contribution to journalArticle

494 Scopus citations

Clinicopathological definition of Waldenstrom's macroglobulinemia: Consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia

Owen, R. G., Treon, S. P., Al-Katib, A., Fonseca, R., Greipp, P. R., McMaster, M. L., Morra, E., Pangalis, G. A., San Miguel, J. F., Branagan, A. R. & Dimopoulos, M. A., Apr 2003, In : Seminars in Oncology. 30, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

573 Scopus citations

Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the International Myeloma Working Group

Kyle, R. A., Child, J. A., Anderson, K., Barlogie, B., Bataille, R., Bensinger, W., Bladé, J., Boccadoro, M., Dalton, W., Dimopoulos, M., Djulbegovic, B., Drayson, M., Durie, B., Facon, T., Fonseca, R., Gahrton, G., Greipp, P., Harousseau, J. L., Harrington, D., Hussein, M. & 19 others, Joshua, D., Ludwig, H., Morgan, G., Oken, M., Powles, R., Richardson, P., Roodman, D., San Miguel, J., Shimizu, K., Shustik, C., Sirohi, B., Sonneveld, P., Tricot, G., Turesson, I., Van Ness, B., Vesole, D., Weber, D., Westin, J. & Wheatley, K., Jun 2003, In : British Journal of Haematology. 121, 5, p. 749-757 9 p.

Research output: Contribution to journalArticle

1699 Scopus citations

Expression of VEGF and its receptors by myeloma cells

Kumar, S. K., Witzig, T. E., Timm, M., Haug, J., Wellik, L., Fonseca, R., Greipp, P. R. & Rajkumar, S. V., Oct 2003, In : Leukemia. 17, 10, p. 2025-2031 7 p.

Research output: Contribution to journalArticle

115 Scopus citations

Genetics and cytogenetics of Waldenstrom's macroglobulinemia

Schop, R. F. J. & Fonseca, R., Apr 2003, In : Seminars in Oncology. 30, 2, p. 142-145 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL)

Abraham, R. S., Geyer, S. M., Price-Troska, T. L., Allmer, C., Kyle, R. A., Gertz, M. & Fonseca, R., May 15 2003, In : Blood. 101, 10, p. 3801-3808 8 p.

Research output: Contribution to journalArticle

165 Scopus citations

Many and multiple myeloma(s)

Fonseca, R., Oct 2003, In : Leukemia. 17, 10, p. 1943-1944 2 p.

Research output: Contribution to journalArticle

19 Scopus citations
27 Scopus citations

POEMS syndrome: Definitions and long-term outcome

Dispenzieri, A., Kyle, R. A., Lacy, M., Rajkumar, S. V., Therneau, T. M., Larson, D. R., Greipp, P. R., Witzig, T. E., Basu, R., Suarez, G. A., Fonseca, R., Lust, J. A. & Gertz, M., Apr 1 2003, In : Blood. 101, 7, p. 2496-2506 11 p.

Research output: Contribution to journalArticle

553 Scopus citations

Poor tolerance to high doses of thalidomide in patients with primary systemic amyloidosis

Dispenzieri, A., Lacy, M., Rajkumar, S. V., Geyer, S. M., Witzig, T. E., Fonseca, R., Lust, J. A., Greipp, P. R., Kyle, R. A. & Gertz, M., Dec 2003, In : Amyloid. 10, 4, p. 257-261 5 p.

Research output: Contribution to journalArticle

112 Scopus citations

Prognostic value of angiogenesis in solitary bone plasmacytoma

Kumar, S. K., Fonseca, R., Dispenzieri, A., Lacy, M., Lust, J. A., Wellik, L., Witzig, T. E., Gertz, M., Kyle, R. A., Greipp, P. R. & Rajkumar, S. V., Mar 1 2003, In : Blood. 101, 5, p. 1715-1717 3 p.

Research output: Contribution to journalArticle

79 Scopus citations

Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma

Kumar, S. K., Gertz, M., Dispenzieri, A., Lacy, M., Geyer, S. M., Iturria, N. L., Fonseca, R., Hayman, S. R., Lust, J. A., Kyle, R. A., Greipp, P. R., Witzig, T. E. & Rajkumar, S. V., Jan 1 2003, In : Mayo Clinic Proceedings. 78, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

122 Scopus citations

Review of 1027 patients with newly diagnosed multiple myeloma

Kyle, R. A., Gertz, M., Witzig, T. E., Lust, J. A., Lacy, M., Dispenzieri, A., Fonseca, R., Rajkumar, S. V., Offord, J. R., Larson, D. R., Plevak, M. E., Therneau, T. M. & Greipp, P. R., Jan 1 2003, In : Mayo Clinic Proceedings. 78, 1, p. 21-33 13 p.

Research output: Contribution to journalArticle

1300 Scopus citations

t(4;14)(P16.3;Q32) is strongly associated with a shorter survival in myeloma patients [5]

Winkler, J. M., Greipp, P. R. & Fonseca, R., 2003, In : British Journal of Haematology. 120, 1, p. 170-171 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Thalidomide as initial therapy for early-stage myeloma

Rajkumar, S. V., Gertz, M., Lacy, M., Dispenzieri, A., Fonseca, R., Geyer, S. M., Iturria, N., Kumar, S. K., Lust, J. A., Kyle, R. A., Greipp, P. R. & Witzig, T. E., Apr 1 2003, In : Leukemia. 17, 4, p. 775-779 5 p.

Research output: Contribution to journalArticle

185 Scopus citations

Thalidomide has activity in treating complex regional pain syndrome [1] (multiple letters)

Schwartzman, R. J., Chevlen, E., Bengtson, K., Rajkumar, S. V., Fonseca, R. & Witzig, T. E., Jul 23 2003, In : Archives of Internal Medicine. 163, 12, p. 1487-1488 2 p.

Research output: Contribution to journalArticle

53 Scopus citations

The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma

Fonseca, R., Debes-Marun, C. S., Picken, E. B., Dewald, G. W., Bryant, S. C., Winkler, J. M., Blood, E., Oken, M. M., Santana-Dávila, R., González-Paz, N., Kyle, R. A., Gertz, M., Dispenzieri, A., Lacy, M. & Greipp, P. R., Oct 1 2003, In : Blood. 102, 7, p. 2562-2567 6 p.

Research output: Contribution to journalArticle

229 Scopus citations

Waldenström macroglobulinaemia

Ghobrial, I. M., Gertz, M. & Fonseca, R., Nov 2003, In : Lancet Oncology. 4, 11, p. 679-685 7 p.

Research output: Contribution to journalArticle

121 Scopus citations
2002

Biological and prognostic significance of interphase fluorescence in situ hybridization detection of chromosome 13 abnormalities (Δ13) in multiple myeloma: An Eastern Cooperative Oncology Group study

Fonseca, R., Harrington, D., Oken, M. M., Dewald, G. W., Bailey, R. J., Rajkumar, S. V., Kay, N. E., Blood, E. A., Rajkumar, S. V., Kay, N. E., Van Ness, B. & Greipp, P. R., Feb 1 2002, In : Cancer Research. 62, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

166 Scopus citations

Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis

Rajkumar, S. V., Mesa, R. A., Fonseca, R., Schroeder, G., Plevak, M. F., Dispenzieri, A., Lacy, M., Lust, J. A., Witzig, T. E., Gertz, M., Kyle, R. A., Russell, S. J. & Greipp, P. R., 2002, In : Clinical Cancer Research. 8, 7, p. 2210-2216 7 p.

Research output: Contribution to journalArticle

269 Scopus citations

Bone marrow angiogenesis in multiple myeloma: Effect of therapy

Kumar, S. K., Fonseca, R., Dispenzieri, A., Lacy, M., Lust, J. A., Witzig, T. E., Gertz, M., Kyle, R. A., Greipp, P. R. & Rajkumar, S. V., 2002, In : British Journal of Haematology. 119, 3, p. 665-671 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma

Rajkumar, S. V., Hayman, S., Gertz, M., Dispenzieri, A., Lacy, M., Greipp, P. R., Geyer, S., Iturria, N., Fonseca, R., Lust, J. A., Kyle, R. A. & Witzig, T. E., Nov 1 2002, In : Journal of Clinical Oncology. 20, 21, p. 4319-4323 5 p.

Research output: Contribution to journalArticle

443 Scopus citations

Deletions of 17p13.1 and 13q14 are uncommon in Waldenström macroglobulinemia clonal cells and mostly seen at the time of disease progression

Schop, R. F. J., Jalal, S. M., Van Wier, S. A., Ahmann, G. J., Bailey, R. J., Kyle, R. A., Greipp, P. R., Rajkumar, S. V., Gertz, M., Lust, J. A., Lacy, M., Dispenzieri, A., Witzig, T. E. & Fonseca, R., Jan 1 2002, In : Cancer Genetics and Cytogenetics. 132, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Genomic abnormalities in monoclonal gammopathy of undetermined significance

Fonseca, R., Bailey, R. J., Ahmann, G. J., Rajkumar, S. V., Hoyer, J., Lust, J. A., Kyle, R. A., Gertz, M., Greipp, P. R. & Dewald, G. W., Aug 15 2002, In : Blood. 100, 4, p. 1417-1424 8 p.

Research output: Contribution to journalArticle

280 Scopus citations

Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients

Fonseca, R., Blood, E. A., Oken, M. M., Kyle, R. A., Dewald, G. W., Bailey, R. J., Van Wier, S. A., Henderson, K. J., Hoyer, J., Harrington, D., Kay, N. E., Van Ness, B. & Greipp, P. R., May 15 2002, In : Blood. 99, 10, p. 3735-3741 7 p.

Research output: Contribution to journalArticle

233 Scopus citations
87 Scopus citations

Waldenström macroglobulinemia neoplastic cells lack immunoglobulin heavy chain locus translocations but have frequent 6q deletions

Schop, R. F. J., Michael Kuehl, W., Van Wier, S. A., Ahmann, G. J., Price-Troska, T., Bailey, R. J., Jalal, S. M., Qi, Y., Kyle, R. A., Greipp, P. R. & Fonseca, R., Oct 15 2002, In : Blood. 100, 8, p. 2996-3001 6 p.

Research output: Contribution to journalArticle

156 Scopus citations
2001

A long-term retrospective study of young women with essential thrombocythemia

Tefferi, A., Fonseca, R., Pereira, D. L. & Clark Hoagland, H., 2001, In : Mayo Clinic Proceedings. 76, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

104 Scopus citations

Complete resolution of reflex sympathetic dystrophy with thalidomide treatment

Rajkumar, S. V., Fonseca, R. & Witzig, T. E., Nov 12 2001, In : Archives of Internal Medicine. 161, 20, p. 2502-2503 2 p.

Research output: Contribution to journalArticle

24 Scopus citations

Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy

Fonseca, R., Oken, M. M., Harrington, D., Bailey, R. J., Van Wier, S. A., Henderson, K. J., Kay, N. E., Van Ness, B., Greipp, P. R. & Dewald, G. W., 2001, In : Leukemia. 15, 6, p. 981-986 6 p.

Research output: Contribution to journalArticle

106 Scopus citations

Detection of diagnostically critical, often hidden, anomalies in complex karyotypes of haematological disorders using multicolour fluorescence in situ hybridization

Jalal, S. M., Law, M. E., Stamberg, J., Fonseca, R., Seely, J. R., Myers, W. H. & Hanson, C. A., 2001, In : British Journal of Haematology. 112, 4, p. 975-980 6 p.

Research output: Contribution to journalArticle

20 Scopus citations