• 30266 Citations
  • 94 Scopus h-Index
19962020
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Research Output 1996 2019

2019

Citron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma

Sahin, I., Kawano, Y., Sklavenitis-Pistofidis, R., Moschetta, M., Mishima, Y., Manier, S., Sacco, A., Carrasco, R., Fonseca, R., Roccaro, A. M., Witzig, T. E. & Ghobrial, I. M., Apr 9 2019, In : Blood Advances. 3, 7, p. 995-1002 8 p.

Research output: Contribution to journalArticle

Open Access
Cytokinesis
Multiple Myeloma
Growth
Neoplasms
Protein-Serine-Threonine Kinases
1 Citation (Scopus)

Incidence of skeletal-related events among multiple myeloma patients in the United States at oncology clinics: Observations from real-world data

Kim, C., Bhatta, S., Cyprien, L., Fonseca, R. & Hernandez, R. K., Feb 1 2019, In : Journal of Bone Oncology. 14, 100215.

Research output: Contribution to journalArticle

Multiple Myeloma
Incidence
History
Proteasome Inhibitors
Electronic Health Records

MYC dysregulation in the progression of multiple myeloma

MMRF CoMMpass Network, Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalLetter

Multiple Myeloma

Review of the patient-centered communication landscape in multiple myeloma and other hematologic malignancies

LeBlanc, T. W., Baile, W. F., Eggly, S., Bylund, C. L., Kurtin, S., Khurana, M., Najdi, R., Blaedel, J., Wolf, J. L. & Fonseca, R., Jan 1 2019, In : Patient Education and Counseling.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Multiple Myeloma
Communication
Publications
Decision Making
2018
1 Citation (Scopus)

Diagnosis and Staging of Multiple Myeloma and Related Disorders

Rajkumar, S. V., Fonseca, R. & San Miguel, J. F., Jan 1 2018, Hematologic Malignancies. 9783319255842 ed. Springer Verlag, p. 17-28 12 p. (Hematologic Malignancies; no. 9783319255842).

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiple Myeloma
Plasma Cell Neoplasms
Therapeutics
Inborn Genetic Diseases
Hypercalcemia
5 Citations (Scopus)

Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients

González-Calle, V., Slack, A., Keane, N., Luft, S., Pearce, K. E., Ketterling, R. P., Jain, T., Chirackal, S., Reeder, C., Mikhael, J. R., Noel, P., Mayo, A., Adams, R. H., Ahmann, G., Braggio, E. D., Stewart, A. K., Bergsagel, P. L., van Wier, S. A. & Fonseca, R., Apr 6 2018, (Accepted/In press) In : Annals of Hematology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Transplants
Survival
Chromosome Aberrations
Stem Cells
3 Citations (Scopus)
Stem Cell Transplantation
Multiple Myeloma
Meta-Analysis
Transplantation
Drug Therapy
3 Citations (Scopus)

Kidney Transplant in the Era of Modern Therapy for Multiple Myeloma

Huskey, J. L., Heilman, R. L., Khamash, H. & Fonseca, R., Dec 1 2018, In : Transplantation. 102, 12, p. 1994-2001 8 p.

Research output: Contribution to journalReview article

Multiple Myeloma
Transplants
Kidney
Kidney Transplantation
Comorbidity

Molecular genetic aspects of plasma cell disorders

Bergsagel, P. L., Stewart, A. K., Russell, S. J. & Fonseca, R., Nov 19 2018, Wintrobe's Clinical Hematology: Fourteenth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 6311-6327 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Plasma Cells
Molecular Biology
3 Citations (Scopus)

Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma

Kumar, S. K., Buadi, F. K., LaPlant, B., Halvorson, A., Leung, N., Kapoor, P., Dingli, D. M., Gertz, M., Go, R. S., Bergsagel, P. L., Lin, Y., Dispenzieri, A., Hwa, Y. L., Fonder, A., Hobbs, M., Fonseca, R., Hayman, S. R., Stewart, A. K., Lust, J. A., Mikhael, J. R. & 5 others, Gonsalves, W., Reeder, C., Skacel, T., Rajkumar, S. V. & Lacy, M., Aug 1 2018, In : Blood Cancer Journal. 8, 8, 70.

Research output: Contribution to journalArticle

Multiple Myeloma
Cyclophosphamide
Dexamethasone
Maximum Tolerated Dose
Proteasome Inhibitors
6 Citations (Scopus)

Pomalidomide-dexamethasone in refractory multiple myeloma: Long-term follow-up of a multi-cohort phase II clinical trial

Ailawadhi, S., Mikhael, J. R., Laplant, B. R., Laumann, K. M., Kumar, S. K., Roy, V., Dingli, D. M., Bergsagel, P. L., Buadi, F. K., Rajkumar, S. V., Fonseca, R., Gertz, M., Kapoor, P., Sher, T., Hayman, S. R., Stewart, A. K., Dispenzieri, A., Kyle, R. A., Gonsalves, W., Reeder, C. B. & 8 others, Lin, Y., Go, R. S., Leung, N., Kourelis, T., Lust, J. A., Russell, S. J., Chanan Khan, A. A. & Lacy, M., Mar 1 2018, In : Leukemia. 32, 3, p. 719-728 10 p.

Research output: Contribution to journalArticle

Phase II Clinical Trials
Multiple Myeloma
Dexamethasone
Appointments and Schedules
Therapeutics
33 Citations (Scopus)

Selective inhibition of nuclear export with oral selinexor for treatment of relapsed or refractory multiple myeloma

Vogl, D. T., Dingli, D. M., Cornell, R. F., Huff, C. A., Jagannath, S., Bhutani, D., Zonder, J., Baz, R., Nooka, A., Richter, J., Cole, C., Vij, R., Jakubowiak, A., Abonour, R., Schiller, G., Parker, T. L., Costa, L. J., Kaminetzky, D., Hoffman, J. E., Yee, A. J. & 12 others, Chari, A., Siegel, D., Fonseca, R., Van Wier, S., Ahmann, G., Lopez, I., Kauffman, M., Shacham, S., Saint-Martin, J. R., Picklesimer, C. D., Choe-Juliak, C. & Stewart, A. K., Jan 1 2018, In : Journal of Clinical Oncology. 36, 9, p. 859-866 8 p.

Research output: Contribution to journalArticle

Cell Nucleus Active Transport
Multiple Myeloma
Rubiaceae
Therapeutics
Dexamethasone
1 Citation (Scopus)

The Importance of Economic Trade-offs in Cancer Drug Pricing

Fonseca, R., Peneva, D., Clancy, Z., Abouzaid, S. & Jena, A. B., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

Economics
Costs and Cost Analysis
Pharmaceutical Preparations
Neoplasms

Treatment With Bortezomib-based Therapy, Followed by Autologous Stem Cell Transplantation, Improves Outcomes in Light Chain Amyloidosis: A Retrospective Study

Jain, T., Kosiorek, H. E., Kung, S. T., Shah, V. S., Dueck, A., Gonzalez-Calle, V., Luft, S., Reeder, C. B., Adams, R., Noel, P., Larsen, J. T., Mikhael, J. R., Bergsagel, P. L., Stewart, A. K. & Fonseca, R., Jan 1 2018, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Amyloidosis
Retrospective Studies
Light
Therapeutics
11 Citations (Scopus)

Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement

Gonsalves, W., Buadi, F. K., Ailawadhi, S., Bergsagel, P. L., Chanan Khan, A. A., Dingli, D. M., Dispenzieri, A., Fonseca, R., Hayman, S. R., Kapoor, P., Kourelis, T. V., Lacy, M., Larsen, J. T., Muchtar, E., Reeder, C. B., Sher, T., Stewart, A. K., Warsame, R., Go, R. S., Kyle, R. A. & 14 others, Leung, N., Lin, Y., Lust, J. A., Russell, S. J., Zeldenrust, S. R., Fonder, A. L., Hwa, Y. L., Hobbs, M. A., Mayo, A. A., Hogan, W., Rajkumar, S. V., Kumar, S. K., Gertz, M. & Roy, V., Jul 9 2018, (Accepted/In press) In : Bone Marrow Transplantation. p. 1-15 15 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Multiple Myeloma
Stem Cells
Transplants
Therapeutics
1 Citation (Scopus)
Costs and Cost Analysis
Pharmaceutical Preparations
Therapeutics
Drug Approval
Pharmaceutical Economics

Waldenström macroglobulinemia

Fonseca, R. & Ansell, S. M., Nov 19 2018, Wintrobe's Clinical Hematology: Fourteenth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 6625-6649 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Waldenstrom Macroglobulinemia
2017
1 Citation (Scopus)

Antibodies Create Killer Bonds in Myeloma

Chesi, M. & Fonseca, R., Mar 13 2017, In : Cancer Cell. 31, 3, p. 305-307 3 p.

Research output: Contribution to journalShort survey

B-Cell Maturation Antigen
Plasma Cells
Multiple Myeloma
B-Lymphocytes
T-Lymphocytes
4 Citations (Scopus)

A phase 2 study of lenalidomide, rituximab, cyclophosphamide, and dexamethasone (LR-CD) for untreated low-grade non-Hodgkin lymphoma requiring therapy

Rosenthal, A., Dueck, A., Ansell, S. M., Gano, K., Conley, C., Nowakowski, G. S., Camoriano, J. K., Leis, J. F., Mikhael, J. R., Stewart, A. K., Inwards, D., Dingli, D. M., Kumar, S. K., Noel, P., Gertz, M., Porrata, L., Russell, S. J., Colgan, J., Fonseca, R., Habermann, T. M. & 6 others, Kapoor, P., Buadi, F., Leung, N., Tiedemann, R., Witzig, T. E. & Reeder, C., May 1 2017, In : American Journal of Hematology. 92, 5, p. 467-472 6 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Cyclophosphamide
Dexamethasone
Lymphoma
B-Cell Lymphoma
42 Citations (Scopus)

Diagnosis and management of Waldenström macroglobulinemia: Mayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) guidelines 2016

Kapoor, P., Ansell, S. M., Fonseca, R., Chanan Khan, A. A., Kyle, R. A., Kumar, S. K., Mikhael, J. R., Witzig, T. E., Mauermann, M. M., Dispenzieri, A., Ailawadhi, S., Stewart, A. K., Lacy, M., Thompson, C. A., Buadi, F. K., Dingli, D. M., Morice, W. G., Go, R. S., Jevremovic, D., Sher, T. & 27 others, King, R. L., Braggio, E. D., Novak, A. J., Roy, V., Ketterling, R. P., Greipp, P. T., Grogan, M., Micallef, I., Bergsagel, P. L., Colgan, J. P., Leung, N., Gonsalves, W., Lin, Y., Inwards, D. J., Hayman, S. R., Nowakowski, G. S., Johnston, P. B., Russell, S. J., Markovic, S. N., Zeldenrust, S. R., Hwa, Y. L., Lust, J. A., Porrata, L. F., Habermann, T. M., Rajkumar, S. V., Gertz, M. & Reeder, C. B., Sep 1 2017, In : JAMA oncology. 3, 9, p. 1257-1265 9 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Guidelines
Stem Cell Transplantation
Therapeutics
Clinical Trials
8 Citations (Scopus)

Hereditary lysozyme amyloidosis variant p.Leu102Ser associates with unique phenotype

Nasr, S. H., Dasari, S., Mills, J. R., Theis, J. D., Zimmermann, M. T., Fonseca, R., Vrana, J. A., Lester, S. J., McLaughlin, B. M., Gillespie, R., Highsmith, W. E. J., Lee, J. J., Dispenzieri, A. & Kurtin, P. J., Feb 1 2017, In : Journal of the American Society of Nephrology. 28, 2, p. 431-438 8 p.

Research output: Contribution to journalArticle

Familial Amyloidosis
Muramidase
Phenotype
Kidney
Amyloid Plaques
5 Citations (Scopus)

Multiple myeloma cells' capacity to decompose H2O2 determines lenalidomide sensitivity

Sebastian, S., Zhu, Y. X., Braggio, E. D., Shi, C. X., Panchabhai, S. C., Van Wier, S. A., Ahmann, G. J., Chesi, M., Bergsagel, P. L., Stewart, A. K. & Fonseca, R., Feb 23 2017, In : Blood. 129, 8, p. 991-1007 17 p.

Research output: Contribution to journalArticle

Thioredoxin-Disulfide Reductase
Multiple Myeloma
Cytotoxicity
Thioredoxins
Cells
1 Citation (Scopus)
Thromboplastin
Thrombosis
Biomarkers
Neoplasms
7 Citations (Scopus)

PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma

Panchabhai, S., Schlam, I., Sebastian, S. & Fonseca, R., Apr 1 2017, In : Leukemia. 31, 4, p. 991-994 4 p.

Research output: Contribution to journalLetter

Multiple Myeloma
Gene Expression
22 Citations (Scopus)

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed lenalidomide-refractory multiple myeloma

Paludo, J., Mikhael, J. R., Laplant, B. R., Halvorson, A. E., Kumar, S. K., Gertz, M., Hayman, S. R., Buadi, F. K., Dispenzieri, A., Lust, J. A., Kapoor, P., Leung, N., Russell, S. J., Dingli, D. M., Go, R. S., Lin, Y., Gonsalves, W., Fonseca, R., Bergsagel, P. L., Roy, V. & 8 others, Sher, T., Chanan Khan, A. A., Ailawadhi, S., Stewart, A. K., Reeder, C. B., Richardson, P. G., Rajkumar, S. V. & Lacy, M., Sep 7 2017, In : Blood. 130, 10, p. 1198-1204 7 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Refractory materials
Dexamethasone
Toxicity
Physical vapor deposition
1 Citation (Scopus)

Precision Medicine in Myeloma: Challenges in Defining an Actionable Approach

González-Calle, V., Keane, N., Braggio, E. D. & Fonseca, R., 2017, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Precision Medicine
Multiple Myeloma
Patient Rights
Pharmaceutical Preparations
Biomarkers

Prevalence of BCL-2/J(H) Translocation in Healthy African Americans

Colon-Otero, G., Van Wier, S. A., Ahmann, G. J., Braggio, E. D., Albertie, M. L., Weis, J. A., Ailawadhi, S., Cerhan, J. R., Vishnu, P., Jorgensen, M. S., Foran, J. M., Thomas, C. S. & Fonseca, R., Jan 1 2017, In : Annals of Hematology. 96, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

African Americans
Follicular Lymphoma
Lymphocytes
Polymerase Chain Reaction
DNA
2 Citations (Scopus)

Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma

van Beers, E. H., van Vliet, M. H., Kuiper, R., de Best, L., Anderson, K. C., Chari, A., Jagannath, S., Jakubowiak, A., Kumar, S. K., Levy, J. B., Auclair, D., Lonial, S., Reece, D., Richardson, P., Siegel, D. S., Stewart, A. K., Trudel, S., Vij, R., Zimmerman, T. M. & Fonseca, R., 2017, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Multiple Myeloma
Centrosome
Testicular Neoplasms
Gene Expression
Antigens

Retos y avances hacia la medicina de precisión en el mieloma múltiple

Translated title of the contribution: Towards precision medicine in myeloma: New evidence and challengesGonzález-Calle, V. & Fonseca, R., Jun 1 2017, In : Medicina (Argentina). 77, 3, p. 222-226 5 p.

Research output: Contribution to journalArticle

Precision Medicine
Multiple Myeloma
Biomarkers
Quality of Life
Clinical Trials
1 Citation (Scopus)

Systolic dysfunction associated with carfilzomib use in patients with multiple myeloma

Jain, T., Narayanasamy, H., Mikhael, J. R., Reeder, C. B., Bergsagel, P. L., Mayo, A., Stewart, A. K., Mookadam, F. & Fonseca, R., Dec 1 2017, In : Blood Cancer Journal. 7, 12, 642.

Research output: Contribution to journalLetter

Multiple Myeloma
carfilzomib
37 Citations (Scopus)

Therapy for Relapsed Multiple Myeloma: Guidelines From the Mayo Stratification for Myeloma and Risk-Adapted Therapy

Dingli, D. M., Ailawadhi, S., Bergsagel, P. L., Buadi, F. K., Dispenzieri, A., Fonseca, R., Gertz, M., Gonsalves, W., Hayman, S. R., Kapoor, P., Kourelis, T., Kumar, S. K., Kyle, R. A., Lacy, M., Leung, N., Lin, Y., Lust, J. A., Mikhael, J. R., Reeder, C. B., Roy, V. & 7 others, Russell, S. J., Sher, T., Stewart, A. K., Warsame, R., Zeldenrust, S. R., Rajkumar, S. V. & Chanan Khan, A. A., Apr 1 2017, In : Mayo Clinic Proceedings. 92, 4, p. 578-598 21 p.

Research output: Contribution to journalReview article

Multiple Myeloma
Guidelines
Recurrence
Patient Care
Therapeutics
66 Citations (Scopus)

Trends in overall survival and costs of multiple myeloma, 2000–2014

Fonseca, R., Abouzaid, S., Bonafede, M., Cai, Q., Parikh, K., Cosler, L. & Richardson, P., Jan 20 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Multiple Myeloma
Costs and Cost Analysis
Survival
United States Social Security Administration
Drug Costs
1 Citation (Scopus)

Use of genetic markers in multiple myeloma

Fonseca, R., Jun 1 2017, In : Clinical Advances in Hematology and Oncology. 15, 6, p. 446-448 3 p.

Research output: Contribution to journalComment/debate

Multiple Myeloma
Genetic Markers
2016

Bone disease in Myeloma: The claws of CRAB

Fonseca, R. & Jain, T., Mar 15 2016, In : Clinical Cancer Research. 22, 6, p. 1301-1303 3 p.

Research output: Contribution to journalArticle

Hoof and Claw
Bone Diseases
Diphosphonates
Biomarkers
Bone and Bones
33 Citations (Scopus)

Carfilzomib and the cardiorenal system in myeloma: An endothelial effect?

Rosenthal, A., Luthi, J., Belohlavek, M., Kortüm, K. M., Mookadam, F., Mayo, A., Fonseca, R., Bergsagel, P. L., Reeder, C. B., Mikhael, J. R. & Stewart, A. K., 2016, In : Blood Cancer Journal. 6, 1, e384.

Research output: Contribution to journalArticle

Creatinine
Clinical Trials
Blood Pressure
Therapeutics
Troponin
50 Citations (Scopus)

Carfilzomib significantly improves the progression-free survival of high-risk patients in multiple myeloma

Avet-Loiseau, H., Fonseca, R., Siegel, D., Dimopoulos, M. A., Špička, I., Masszi, T., Hájek, R., Rosiñol, L., Goranova-Marinova, V., Mihaylov, G., Maisnar, V., Mateos, M. V., Wang, M., Niesvizky, R., Oriol, A., Jakubowiak, A., Minarik, J., Palumbo, A., Bensinger, W., Kukreti, V. & 4 others, Ben-Yehuda, D., Stewart, A. K., Obreja, M. & Moreau, P., Sep 1 2016, In : Blood. 128, 9, p. 1174-1180 7 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Cytogenetics
Disease-Free Survival
Dexamethasone
carfilzomib
10 Citations (Scopus)

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., Ritacca, N. R., McCullough, A. E., Barrett, M., Hunt, K. S., Champion, M. D., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Mc Williams, R. R., Lazaridis, K. N., Ramanathan, R. K., Baker, A., Aldrich, J. & 17 others, Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Valdez, R., Jaroszewski, D. E., Von Hoff, D. D., Craig, D. W., Stewart, A. K., Carpten, J. D. & Bryce, A. H., 2016, In : Scientific Reports. 6, 1, 25.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
DNA Fingerprinting
Patient Preference
Pharmaceutical Preparations

Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib

Bryce, A. H., Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., McCullough, A. E., Hunt, K. S., Ritacca, N. R., Barrett, M., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Stanton, M. L., Cheville, J., Swanson, S., Schneider, D. E., Mc Williams, R. R. & 16 others, Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Von Hoff, D. D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Nov 3 2016, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Erdheim Chester Disease treated successfully with cladribine

Azadeh, N., Tazelaar, H. D., Gotway, M., Mookadam, F. & Fonseca, R., 2016, In : Respiratory Medicine Case Reports. 18, p. 37-40 4 p.

Research output: Contribution to journalArticle

Erdheim-Chester Disease
Cladribine
Mutation
Monocytes
Proto-Oncogene Proteins B-raf
15 Citations (Scopus)

Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome

Barrio, S., Shanafelt, T. D., Ojha, J., Chaffee, K. G., Secreto, C., Kortüm, K. M., Pathangey, S., Van-Dyke, D. L., Slager, S. L., Fonseca, R., Kay, N. E. & Braggio, E. D., Jul 29 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Lymphocytosis
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Mutation
Clonal Evolution
49 Citations (Scopus)

IAP antagonists induce anti-tumor immunity in multiple myeloma

Chesi, M., Mirza, N. N., Garbitt, V. M., Sharik, M. E., Dueck, A., Asmann, Y., Akhmetzyanova, I., Kosiorek, H. E., Calcinotto, A., Riggs, D. L., Keane, N., Ahmann, G. J., Morrison, K. M., Fonseca, R., Lacy, M., Dingli, D. M., Kumar, S. K., Ailawadhi, S., Dispenzieri, A., Buadi, F. & 7 others, Gertz, M., Reeder, C. B., Lin, Y., Chanan Khan, A. A., Stewart, A. K., Fooksman, D. & Bergsagel, P. L., Dec 1 2016, In : Nature Medicine. 22, 12, p. 1411-1420 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Tumors
Immunity
Apoptosis
Neoplasms
5 Citations (Scopus)

Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in patients with newly diagnosed multiple myeloma on the ECOG-ACRIN E4A03 randomized clinical trial: Long-term follow-up

Biran, N., Jacobus, S., Vesole, D. H., Callander, N. S., Fonseca, R., Williams, M. E., Abonour, R., Katz, M. S., Rajkumar, S. V., Greipp, P. R. & Siegel, D. S., Sep 2 2016, In : Blood Cancer Journal. 6, 9, e466.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Multiple Myeloma
Dexamethasone
Randomized Controlled Trials
Transplants
24 Citations (Scopus)

Panel sequencing for clinically oriented variant screening and copy number detection in 142 untreated multiple myeloma patients

Kortuem, K. M., Braggio, E. D., Bruins, L., Barrio, S., Shi, C. S., Zhu, Y. X., Tibes, R., Viswanatha, D., Votruba, P., Ahmann, G., Fonseca, R., Jedlowski, P., Schlam, I., Kumar, S. K., Bergsagel, P. L. & Stewart, A. K., 2016, In : Blood Cancer Journal. 6, 2, e397.

Research output: Contribution to journalArticle

Multiple Myeloma
Mutation
Genes
Costs and Cost Analysis
Pharmaceutical Preparations
2 Citations (Scopus)

Phase II trial of nab-paclitaxel in patients with relapsed or refractory multiple myeloma

Jain, T., Dueck, A., Kosiorek, H. E., Ginos, B. F., Mayo, A., Reeder, C. B., Chesi, M., Mikhael, J. R., Stewart, A. K., Bergsagel, P. L. & Fonseca, R., Dec 1 2016, In : American Journal of Hematology. 91, 12, p. E504-E505

Research output: Contribution to journalLetter

Multiple Myeloma
130-nm albumin-bound paclitaxel
13 Citations (Scopus)

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation

Teoh, P. J., Bi, C., Sintosebastian, C., Tay, L. S., Fonseca, R. & Chng, W. J., 2016, In : Oncotarget. 7, 38, p. 61806-61819 14 p.

Research output: Contribution to journalArticle

Myeloma Proteins
Endoplasmic Reticulum Stress
Multiple Myeloma
Homeostasis
Protein Conformation
2 Citations (Scopus)
Multiple Myeloma
Dexamethasone
Therapeutics
lenalidomide
Bortezomib
16 Citations (Scopus)

Tumor-associated macrophages and extracellular matrix metalloproteinase inducer in prognosis of multiple myeloma

Panchabhai, S., Kelemen, K., Ahmann, G., Sebastian, S., Mantei, J. & Fonseca, R., Apr 1 2016, In : Leukemia. 30, 4, p. 951-954 4 p.

Research output: Contribution to journalLetter

CD147 Antigens
Tissue Array Analysis
Neoplasm Staging
Tumor Biomarkers
Stromal Cells
2015
10 Citations (Scopus)

Carfilzomib: A cause of drug associated thrombotic microangiopathy

Qaqish, I., Schlam, I. M., Chakkera, H. M., Fonseca, R. & Adamski, J., Aug 24 2015, (Accepted/In press) In : Transfusion and Apheresis Science.

Research output: Contribution to journalArticle

Thrombotic Microangiopathies
Plasma Exchange
Multiple Myeloma
Pharmaceutical Preparations
Therapeutics
35 Citations (Scopus)

Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia

Ojha, J., Ayres, J., Secreto, C., Tschumper, R., Rabe, K., Van Dyke, D., Slager, S. L., Shanafelt, T., Fonseca, R., Kay, N. E. & Braggio, E. D., Jan 15 2015, In : Blood. 125, 3, p. 492-498 7 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Genetic Heterogeneity
B-Cell Chronic Lymphocytic Leukemia
Genes
Microarrays
77 Citations (Scopus)

Dinaciclib, a novel CDK inhibitor, demonstrates encouraging single-agent activity in patients with relapsed multiple myeloma

Mayo Phase Consortium, Jan 15 2015, In : Blood. 125, 3, p. 443-448 6 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Multiple Myeloma
CDC2 Protein Kinase
Proteasome Inhibitors
Stabilization