Purna C Kashyap, MBBS &ndash; Research Output

2019

A decreased abundance of clostridia characterizes the gut microbiota in eosinophilic esophagitis

Kashyap, P. C., Johnson, S., Geno, D. M., Lekatz, H. R., Lavey, C., Alexander, J. A., Chen, J. & Katzka, D. A., Oct 1 2019, In : Physiological reports. 7, 20, e14261.

Research output: Contribution to journal › Article

Open Access

Eosinophilic Esophagitis

Clostridium

Asthma

Bacteroidetes

Budesonide

2 Citations (Scopus)

An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study

Muñiz Pedrogo, D. A., Chen, J., Hillmann, B., Jeraldo, P., Al-Ghalith, G., Taneja, V., Davis, J. M., Knights, D., Nelson, H., Faubion, W. A., Raffals, L. & Kashyap, P. C., Apr 11 2019, In : Inflammatory bowel diseases. 25, 5, p. 902-913 12 p.

Research output: Contribution to journal › Article

Inflammatory Bowel Diseases

Arthritis

Rheumatoid Arthritis

Cross-Sectional Studies

Joint Diseases

9 Citations (Scopus)

Assessment of a Personalized Approach to Predicting Postprandial Glycemic Responses to Food Among Individuals Without Diabetes

Mendes-Soares, H., Raveh-Sadka, T., Azulay, S., Edens, K., Ben-Shlomo, Y., Cohen, Y., Ofek, T., Bachrach, D., Stevens, J., Colibaseanu, D., Segal, L., Kashyap, P. C. & Nelson, H., Feb 1 2019, In : JAMA network open. 2, 2, p. e188102

Research output: Contribution to journal › Article

Open Access

Food

Microbiota

Blood Glucose

Carbohydrates

Standard of Care

2 Citations (Scopus)

Model of personalized postprandial glycemic response to food developed for an Israeli cohort predicts responses in Midwestern American individuals

Mendes-Soares, H., Raveh-Sadka, T., Azulay, S., Ben-Shlomo, Y., Cohen, Y., Ofek, T., Stevens, J., Bachrach, D., Kashyap, P. C., Segal, L. & Nelson, H., Jul 1 2019, In : American Journal of Clinical Nutrition. 110, 1, p. 63-75 13 p., nzq028.

Research output: Contribution to journal › Article

Open Access

Meals

Food

Microbiota

Aptitude

Age Distribution

Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS

Edogawa, S., Edwinson, A. L., Peters, S. A., Chikkamenahalli, L. L., Sundt, W., Graves, S., Gurunathan, S. V., Breen-Lyles, M., Johnson, S., Dyer, R., Graham, R., Chen, J., Kashyap, P., Farrugia, G. & Grover, M., Jan 1 2019, In : Gut.

Research output: Contribution to journal › Article

Serine Proteases

Microbiota

Permeability

Occludin

Healthy Volunteers

3 Citations (Scopus)

Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders

Saffouri, G. B., Shields-Cutler, R. R., Chen, J., Yang, Y., Lekatz, H. R., Hale, V. L., Cho, J. M., Battaglioli, E. J., Bhattarai, Y., Thompson, K. J., Kalari, K. K., Behera, G., Berry, J. C., Peters, S. A., Patel, R., Schuetz, A. N., Faith, J. J., Camilleri, M., Sonnenburg, J. L., Farrugia, G. & 4 others, Swann, J. R., Grover, M., Knights, D. & Kashyap, P. C., Dec 1 2019, In : Nature communications. 10, 1, 2012.

Research output: Contribution to journal › Article

Open Access

Dysbiosis

Gastrointestinal Diseases

Nutrition

diets

disorders

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Ridlon, J. M., Devendran, S., Alves, J. M., Doden, H., Wolf, P. G., Pereira, G. V., Ly, L., Volland, A., Takei, H., Nittono, H., Murai, T., Kurosawa, T., Chlipala, G. E., Green, S. J., Hernandez, A. G., Fields, C. J., Wright, C. L., Kakiyama, G., Cann, I., Kashyap, P. C. & 2 others, McCracken, V. & Gaskins, H. R., Jan 1 2019, In : Gut Microbes.

Research output: Contribution to journal › Article

Germ-Free Life

Metabolomics

Genomics

Bile Acids and Salts

Life Style

2018

10 Citations (Scopus)

Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea

Battaglioli, E. J., Hale, V. L., Chen, J., Jeraldo, P., Ruiz-Mojica, C., Schmidt, B. A., Rekdal, V. M., Till, L. M., Huq, L., Smits, S. A., Moor, W. J., Jones-Hall, Y., Smyrk, T. C., Khanna, S., Pardi, D. S., Grover, M., Patel, R., Chia, N. D., Nelson, H., Sonnenburg, J. L. & 2 others, Farrugia, G. & Kashyap, P. C., Oct 24 2018, In : Science Translational Medicine. 10, 464, eaam7019.

Research output: Contribution to journal › Article

Dysbiosis

Diarrhea

Amino Acids

Infection

Proline

11 Citations (Scopus)

Enterococcus faecalis sex pheromone cCF10 enhances conjugative plasmid transfer in vivo

Hirt, H., Greenwood-Quaintance, K. E., Karau, M. J., Till, L. M., Kashyap, P. C., Patel, R. & Dunny, G. M., Jan 1 2018, In : mBio. 9, 1, e00037-18.

Research output: Contribution to journal › Article

Sex Attractants

Enterococcus faecalis

Plasmids

Pheromones

Bacteriocins

5 Citations (Scopus)

Gut Microbial Carbohydrate Metabolism Hinders Weight Loss in Overweight Adults Undergoing Lifestyle Intervention With a Volumetric Diet

Muñiz Pedrogo, D. A., Jensen, M. D., Van Dyke, C. T., Murray, J. A., Woods, J. A., Chen, J., Kashyap, P. C. & Nehra, V., Aug 1 2018, In : Mayo Clinic Proceedings. 93, 8, p. 1104-1110 7 p.

Research output: Contribution to journal › Article

Carbohydrate Metabolism

Life Style

Weight Loss

Diet

Obesity

26 Citations (Scopus)

Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion

Bhattarai, Y., Williams, B. B., Battaglioli, E. J., Whitaker, W. R., Till, L., Grover, M., Linden, D. R., Akiba, Y., Kandimalla, K. K., Zachos, N. C., Kaunitz, J. D., Sonnenburg, J. L., Fischbach, M. A., Farrugia, G. & Kashyap, P. C., Jun 13 2018, In : Cell Host and Microbe. 23, 6, p. 775-785.e5

Research output: Contribution to journal › Article

Receptors, Serotonin, 5-HT4

G-Protein-Coupled Receptors

Gastrointestinal Transit

Fluids and Secretions

Tryptophan

6 Citations (Scopus)

Increased Prevalence of Rare Sucrase-isomaltase (SI) Pathogenic Variants in Irritable Bowel Syndrome Patients

Garcia-Etxebarria, K., Zheng, T., Bonfiglio, F., Bujanda, L., Dlugosz, A., Lindberg, G., Schmidt, P. T., Karling, P., Ohlsson, B., Simren, M., Walter, S., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P., Bellini, M., Barbara, G., Jonkers, D. & 10 others, Eswaran, S., Chey, W. D., Kashyap, P. C., Chang, L., Mayer, E. A., Wouters, M. M., Boeckxstaens, G., Camilleri, M., Franke, A. & D'Amato, M., Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journal › Article

Oligo-1,6-Glucosidase

Sucrase

Irritable Bowel Syndrome

Dietary Sucrose

Disaccharidases

5 Citations (Scopus)

Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota

Edogawa, S., Peters, S. A., Jenkins, G. D., Gurunathan, S. V., Sundt, W. J., Johnson, S., Lennon, R. J., Dyer, R. B., Camilleri, M., Kashyap, P. C., Farrugia, G., Chen, J., Singh, R. J. & Grover, M., Dec 1 2018, In : FASEB Journal. 32, 12, p. 6615-6625 11 p.

Research output: Contribution to journal › Article

Microbiota

Non-Steroidal Anti-Inflammatory Agents

Indomethacin

Sex Characteristics

Permeability

49 Citations (Scopus)

US Immigration Westernizes the Human Gut Microbiome

Vangay, P., Johnson, A. J., Ward, T. L., Al-Ghalith, G. A., Shields-Cutler, R. R., Hillmann, B. M., Lucas, S. K., Beura, L. K., Thompson, E. A., Till, L. M., Batres, R., Paw, B., Pergament, S. L., Saenyakul, P., Xiong, M., Kim, A. D., Kim, G., Masopust, D., Martens, E. C., Angkurawaranon, C. & 4 others, McGready, R., Kashyap, P. C., Culhane-Pera, K. A. & Knights, D., Nov 1 2018, In : Cell. 175, 4, p. 962-972.e10

Research output: Contribution to journal › Article

Microbiota

Metabolic Diseases

Emigration and Immigration

Metagenomics

Firearms

2017

Beware! Are bacteria raising your oxidative stress?

Kashyap, P. C., Feb 22 2017, In : Science Translational Medicine. 9, 378

Research output: Contribution to journal › Article

Colonic Neoplasms

Oxidative Stress

Bacteria

Azoxymethane

Porphyromonas

31 Citations (Scopus)

Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease

Khanna, S., Vazquez-Baeza, Y., González, A., Weiss, S., Schmidt, B., Muñiz-Pedrogo, D. A., Rainey, J. F., Kammer, P., Nelson, H., Sadowsky, M., Khoruts, A., Farrugia, S. L., Knight, R., Pardi, D. S. & Kashyap, P. C., May 15 2017, In : Microbiome. 5, 1, p. 55 1 p.

Research output: Contribution to journal › Article

Clostridium Infections

Clostridium difficile

Ecology

Inflammatory Bowel Diseases

Infection

11 Citations (Scopus)

Enterococcus faecalis readily colonizes the entire gastrointestinal tract and forms biofilms in a germ-free mouse model

Barnes, A. M. T., Dale, J. L., Chen, Y., Manias, D. A., Greenwood Quaintance, K. E., Karau, M. K., Kashyap, P. C., Patel, R., Wells, C. L. & Dunny, G. M., Feb 6 2017, (Accepted/In press) In : Virulence. p. 1-15 15 p.

Research output: Contribution to journal › Article

Enterococcus faecalis

Biofilms

Gastrointestinal Tract

Lower Gastrointestinal Tract

Bacteria

23 Citations (Scopus)

Exercise training-induced modification of the gut microbiota persists after microbiota colonization and attenuates the response to chemically-induced colitis in gnotobiotic mice

Allen, J. M., Mailing, L. J., Cohrs, J., Salmonson, C., Fryer, J. D., Nehra, V., Hale, V. L., Kashyap, P. C., White, B. A. & Woods, J. A., Sep 19 2017, (Accepted/In press) In : Gut Microbes. p. 1-16 16 p.

Research output: Contribution to journal › Article

Germ-Free Life

Microbiota

Colitis

Exercise

Tissue Donors

22 Citations (Scopus)

Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT₃ receptor expression via acetate production

Bhattarai, Y., Schmidt, B. A., Linden, D. R., Larson, E. D., Grover, M., Beyder, A., Farrugia, G. & Kashyap, P. C., 2017, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 313, 1, p. G80-G87

Research output: Contribution to journal › Article

Receptors, Serotonin, 5-HT3

Serotonin

Acetates

Intestinal Secretions

Ondansetron

Metabolites and microbial composition of stool of women with fecal incontinence: Study design and methods

Arya, L. A., Richter, H. E., Jelovsek, E., Gantz, M., Cichowski, S., Zyczynski, H., Dyer, K., Siddiqui, N., Carberry, C., Broeckling, C., Morrow, C., Kashyap, P. C. & Meikle, S., 2017, (Accepted/In press) In : Neurourology and Urodynamics.

Research output: Contribution to journal › Article

Fecal Incontinence

Pelvic Floor Disorders

Loperamide

Specimen Handling

House Calls

8 Citations (Scopus)

Mutual reinforcement of pathophysiological host-microbe interactions in intestinal stasis models

Touw, K., Ringus, D. L., Hubert, N., Wang, Y., Leone, V. A., Nadimpalli, A., Theriault, B. R., Huang, Y. E., Tune, J. D., Herring, P. B., Farrugia, G., Kashyap, P. C., Antonopoulos, D. A. & Chang, E. B., Mar 1 2017, In : Physiological Reports. 5, 6, e13182.

Research output: Contribution to journal › Article

Constipation

Loperamide

Microbiota

Dysbiosis

Gastrointestinal Transit

4 Citations (Scopus)

Screening for Clostridium difficile colonization on admission to a hematopoietic stem cell transplant unit may reduce hospital-acquired C difficile infection

Cho, J., Seville, M. T., Khanna, S., Pardi, D. S., Sampathkumar, P. & Kashyap, P. C., Jan 1 2017, (Accepted/In press) In : American Journal of Infection Control.

Research output: Contribution to journal › Article

Clostridium difficile

Hematopoietic Stem Cells

Transplants

Infection

Clostridium Infections

2016

7 Citations (Scopus)

Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction

Chen, J., Toyomasu, Y., Hayashi, Y., Linden, D. R., Szurszewski, J. H., Nelson, H., Farrugia, G., Kashyap, P. C., Chia, N. D. & Ordog, T., Oct 3 2016, In : Genome Medicine. 8, 1, 103.

Research output: Contribution to journal › Article

Microbiota

Weaning

Body Weight

Body Weight Changes

Somatomedins

2 Citations (Scopus)

Correlated gene expression encoding serotonin (5-HT) receptor 4 and 5-HT transporter in proximal colonic segments of mice across different colonization states and sexes

Reigstad, C. S., Linden, D. R., Szurszewski, J. H., Sonnenburg, J. L., Farrugia, G. & Kashyap, P. C., Sep 1 2016, In : Neurogastroenterology and Motility. 28, 9, p. 1443-1448 6 p.

Research output: Contribution to journal › Article

Serotonin Receptors

Serotonin

Gene Expression

Free Association

Irritable Bowel Syndrome

12 Citations (Scopus)

Germ-free mice model for studying host–microbial interactions

Bhattarai, Y. & Kashyap, P. C., May 1 2016, In : Methods in Molecular Biology. 1438, p. 123-135 13 p.

Research output: Contribution to journal › Article

Germ-Free Life

Obesity

Health

24 Citations (Scopus)

Gut microbiome predictors of treatment response and recurrence in primary Clostridium difficile infection

Khanna, S., Montassier, E., Schmidt, B., Patel, R., Knights, D., Pardi, D. S. & Kashyap, P. C., 2016, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journal › Article

Clostridium Infections

Clostridium difficile

Recurrence

Therapeutics

Area Under Curve

35 Citations (Scopus)

High risk of post-infectious irritable bowel syndrome in patients with Clostridium difficile infection

Wadhwa, A., Al Nahhas, M. F., Dierkhising, R. A., Patel, R., Kashyap, P. C., Pardi, D. S., Khanna, S. & Grover, M., Sep 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 6, p. 576-582 7 p.

Research output: Contribution to journal › Article

Clostridium Infections

Clostridium difficile

Irritable Bowel Syndrome

Odds Ratio

Anxiety

13 Citations (Scopus)

Individualized responses of gut microbiota to dietary intervention modeled in humanized mice

Smits, S. A., Marcobal, A., Higginbottom, S., Sonnenburg, J. L. & Kashyap, P. C., Sep 1 2016, In : mSystems. 1, 5, e00098.

Research output: Contribution to journal › Article

Microbiota

Metabolites

intestinal microorganisms

Mouse

metabolite

13 Citations (Scopus)

Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: A feasibility study (with video)

Rajan, E., Gostout, C. J., Wong Kee Song, L. M., Szarka, L., Kashyap, P. C., Smyrk, T. C., Bingener, J., Deters, J. L., Knipschield, M. A., Bernard, C. E. & Farrugia, G., Feb 22 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journal › Article

Interstitial Cells of Cajal

Gastroparesis

Feasibility Studies

Stomach

Biopsy

12 Citations (Scopus)

Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice

Choi, K. M., Gibbons, S. J., Sha, L., Beyder, A., Verhulst, P. J., Cipriani, G., Phillips, J. E., Bauer, A. J., Ordog, T., Camp, J. J., Ge, X., Bharucha, A. E., Linden, D. R., Szurszewski, J. H., Kashyap, P. C. & Farrugia, G., Jul 1 2016, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 2, 4, p. 454-467 14 p.

Research output: Contribution to journal › Article

Interstitial Cells of Cajal

Gastric Emptying

Interleukin-10

Heme Oxygenase-1

Stomach

39 Citations (Scopus)

Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces

Wang, F., Knutson, K., Alcaino, C., Linden, D. R., Gibbons, S. J., Kashyap, P. C., Grover, M., Oeckler, R., Gottlieb, P. A., Li, H. J., Leiter, A. B., Farrugia, G. & Beyder, A., 2016, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journal › Article

Enterochromaffin Cells

Ion Channels

Serotonin

Epithelium

Jejunum

2015

218 Citations (Scopus)

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

Reigstad, C. S., Salmonson, C. E., Rainey, J. F., Szurszewski, J. H., Linden, D. R., Sonnenburg, J. L., Farrugia, G. & Kashyap, P. C., Apr 1 2015, In : FASEB Journal. 29, 4, p. 1395-1403 9 p.

Research output: Contribution to journal › Article

Enterochromaffin Cells

Volatile Fatty Acids

Serotonin

Gastrointestinal Motility

Receptors, Serotonin, 5-HT4

2014

117 Citations (Scopus)

Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine

Williams, B. B., Van Benschoten, A. H., Cimermancic, P., Donia, M. S., Zimmermann, M., Taketani, M., Ishihara, A., Kashyap, P. C., Fraser, J. S. & Fischbach, M. A., Oct 8 2014, In : Cell Host and Microbe. 16, 4, p. 495-503 9 p.

Research output: Contribution to journal › Article

Aromatic-L-Amino-Acid Decarboxylases

Carboxy-Lyases

Neurotransmitter Agents

Tryptophan

Gastrointestinal Microbiome

100 Citations (Scopus)

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism

Tong, M., McHardy, I., Ruegger, P., Goudarzi, M., Kashyap, P. C., Haritunians, T., Li, X., Graeber, T. G., Schwager, E., Huttenhower, C., Fornace, A. J., Sonnenburg, J. L., McGovern, D. P. B., Borneman, J. & Braun, J., Nov 25 2014, In : ISME Journal. 8, 11, p. 2193-2206 14 p.

Research output: Contribution to journal › Article

Crohn disease

Crohn Disease

energy metabolism

Energy Metabolism

polymorphism

2013

142 Citations (Scopus)

A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice

Marcobal, A., Kashyap, P. C., Nelson, T. A., Aronov, P. A., Donia, M. S., Spormann, A., Fischbach, M. A. & Sonnenburg, J. L., Oct 2013, In : ISME Journal. 7, 10, p. 1933-1943 11 p.

Research output: Contribution to journal › Article

Germ-Free Life

metabolome

Metabolomics

Metabolome

metabolomics

183 Citations (Scopus)

Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice

Kashyap, P. C., Marcobal, A., Ursell, L. K., Larauche, M., Duboc, H., Earle, K. A., Sonnenburg, E. D., Ferreyra, J. A., Higginbottom, S. K., Million, M., Tache, Y., Pasricha, P. J., Knight, R., Farrugia, G. & Sonnenburg, J. L., May 2013, In : Gastroenterology. 144, 5, p. 967-977 11 p.

Research output: Contribution to journal › Article

Gastrointestinal Transit

Diet

Microbiota

Polysaccharides

Gastrointestinal Microbiome

127 Citations (Scopus)

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

Kashyap, P. C., Marcobal, A., Ursell, L. K., Smits, S. A., Sonnenburg, E. D., Costello, E. K., Higginbottom, S. K., Domino, S. E., Holmes, S. P., Relman, D. A., Knight, R., Gordon, J. I. & Sonnenburg, J. L., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17059-17064 6 p.

Research output: Contribution to journal › Article

Mucus

Polysaccharides

Carbohydrates

Diet

Germ-Free Life

416 Citations (Scopus)

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

Ng, K. M., Ferreyra, J. A., Higginbottom, S. K., Lynch, J. B., Kashyap, P. C., Gopinath, S., Naidu, N., Choudhury, B., Weimer, B. C., Monack, D. M. & Sonnenburg, J. L., 2013, In : Nature. 502, 7469, p. 96-99 4 p.

Research output: Contribution to journal › Article

Microbiota

N-Acetylneuraminic Acid

Anti-Bacterial Agents

Clostridium difficile

Carbohydrates

120 Citations (Scopus)

Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota

Wieland Brown, L. C., Penaranda, C., Kashyap, P. C., Williams, B. B., Clardy, J., Kronenberg, M., Sonnenburg, J. L., Comstock, L. E., Bluestone, J. A. & Fischbach, M. A., Jul 2013, In : PLoS Biology. 11, 7, e1001610.

Research output: Contribution to journal › Article

Galactosylceramides

sphingolipids

Sphingolipids

intestinal microorganisms

Bacteroides

2 Citations (Scopus)

Role of diet and gut microbiota in management of inflammatory bowel disease in an Asian migrant

Kashyap, P. C., Reigstad, C. S. & Loftus, Jr, E. V., Jul 2013, In : Journal of Allergy and Clinical Immunology. 132, 1

Research output: Contribution to journal › Article

Metagenome

Inflammatory Bowel Diseases

Gastrointestinal Tract

Diet

Gastrointestinal Microbiome

2011

3 Citations (Scopus)

Esophageal papillomas and skin abnormalities

Kashyap, P. C., Sweetser, S. & Farrugia, G., Mar 2011, In : Gastroenterology. 140, 3

Research output: Contribution to journal › Article

Focal Dermal Hypoplasia

Skin Abnormalities

Esophagoscopy

Papilloma

Genetic Predisposition to Disease

32 Citations (Scopus)

Immunoreactivity for Ano1 detects depletion of Kit-positive interstitial cells of Cajal in patients with slow transit constipation

Kashyap, P. C., Gomez-Pinilla, P. J., Pozo, M. J., Cima, R. R., Dozois, E., Larson, D., Ordog, T., Gibbons, S. J. & Farrugia, G., Aug 2011, In : Neurogastroenterology and Motility. 23, 8, p. 760-765 6 p.

Research output: Contribution to journal › Article

Interstitial Cells of Cajal

Constipation

Cell Count

Gastrointestinal Motility

Receptor Protein-Tyrosine Kinases

45 Citations (Scopus)

Oxidative stress: Key player in gastrointestinal complications of diabetes

Kashyap, P. C. & Farrugia, G., Feb 2011, In : Neurogastroenterology and Motility. 23, 2, p. 111-114 4 p.

Research output: Contribution to journal › Article

Diabetes Complications

Oxidative Stress

Oxidants

Gastrointestinal Tract

Thioctic Acid

1 Citation (Scopus)

Percutaneous endoscopic gastrostomy tract salvage using natural orifice transluminal endoscopic surgery technique (with video)

Sweetser, S., Kashyap, P. C. & Baron, T. H., Apr 2011, In : Gastrointestinal Endoscopy. 73, 4, p. 839-840 2 p.

Research output: Contribution to journal › Article

Natural Orifice Endoscopic Surgery

Esophageal Stenosis

Salvage Therapy

Gastrostomy

2010

45 Citations (Scopus)

Carbon monoxide reverses diabetic gastroparesis in NOD mice

Kashyap, P. C., Choi, K. M., Dutta, N., Linden, D. R., Szurszewski, J. H., Gibbons, S. J. & Farrugia, G., Jun 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 298, 6

Research output: Contribution to journal › Article

Gastroparesis

Inbred NOD Mouse

Carbon Monoxide

Gastric Emptying

Heme Oxygenase-1

121 Citations (Scopus)

CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice

Choi, K. M., Kashyap, P. C., Dutta, N., Stoltz, G. J., Ordog, T., Shea Donohue, T., Bauer, A. J., Linden, D. R., Szurszewski, J. H., Gibbons, S. J. & Farrugia, G., Jun 2010, In : Gastroenterology. 138, 7

Research output: Contribution to journal › Article

Gastroparesis

Heme Oxygenase-1

Macrophages

Gastric Emptying

Stomach

121 Citations (Scopus)

Diabetic gastroparesis: What we have learned and had to unlearn in the past 5 years

Kashyap, P. C. & Farrugia, G., Dec 2010, In : Gut. 59, 12, p. 1716-1726 11 p.

Research output: Contribution to journal › Article

Gastroparesis

Nausea

Vomiting

Stomach

Interstitial Cells of Cajal

15 Citations (Scopus)

HMGA1 and HMGA2 rearrangements in mass-forming endometriosis

Medeiros, F., Araujo, A. R., Erickson-Johnson, M. R., Kashyap, P. C., Dal Cin, P., Nucci, M., Wang, X., Bell, D. A. & Oliveira, A. M., Jul 2010, In : Genes Chromosomes and Cancer. 49, 7, p. 630-634 5 p.

Research output: Contribution to journal › Article

Endometriosis

Fluorescence In Situ Hybridization

Cytogenetics

HMGA Proteins

Lung

Nephrogenic systemic fibrosis following acute kidney injury and exposure to gadolinium

Bhaskaran, A., Kashyap, P. C., Kelly, B. & Ghera, P., Jan 1 2010, In : Indian Journal of Medical Sciences. 64, 1, p. 33-36 4 p.

Research output: Contribution to journal › Article

Nephrogenic Fibrosing Dermopathy

Gadolinium

Acute Kidney Injury

Lupus Nephritis

Systemic Scleroderma

2009

7 Citations (Scopus)

The D2/D3 agonist PD128907 (R-(+)-trans-3,4a,10b-tetrahydro-4-Propyl-2H,5H- [1]benzopyrano[4,3-b]-1,4-oxazin-9-ol) inhibits stimulated pyloric relaxation and spontaneous gastric emptying

Kashyap, P. C., Micci, M. A., Pasricha, S. & Pasricha, P. J., Jan 2009, In : Digestive Diseases and Sciences. 54, 1, p. 57-62 6 p.

Research output: Contribution to journal › Article

Gastric Emptying

Dopamine Receptors

Dopamine Antagonists

Dopamine

Stomach